LOCUS       DAVLAQ010000001        83226 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000001 DAVLAQ010000000
VERSION     DAVLAQ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.001"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            58..1950
                     /gene="pepO"
                     /locus_tag="VXB71_000001"
     CDS             58..1950
                     /gene="pepO"
                     /locus_tag="VXB71_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0450186.1"
                     /translation="MTRYQDDFYDAINGKWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2073..2702)
                     /locus_tag="VXB71_000002"
     CDS             complement(2073..2702)
                     /locus_tag="VXB71_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0450187.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(3042..3284)
                     /locus_tag="VXB71_000003"
     CDS             complement(3042..3284)
                     /locus_tag="VXB71_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450188.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            3695..5917
                     /locus_tag="VXB71_000004"
     CDS             3695..5917
                     /locus_tag="VXB71_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0450189.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5947..6390
                     /locus_tag="VXB71_000005"
     CDS             5947..6390
                     /locus_tag="VXB71_000005"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0450190.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6429..6843)
                     /locus_tag="VXB71_000006"
                     /pseudo
     CDS             complement(6429..6843)
                     /locus_tag="VXB71_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7202..7564
                     /locus_tag="VXB71_000007"
     CDS             7202..7564
                     /locus_tag="VXB71_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450191.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            7972..8271
                     /locus_tag="VXB71_000008"
     CDS             7972..8271
                     /locus_tag="VXB71_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450192.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(8366..8803)
                     /locus_tag="VXB71_000009"
     CDS             complement(8366..8803)
                     /locus_tag="VXB71_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450193.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(8934..9569)
                     /locus_tag="VXB71_000010"
     CDS             complement(8934..9569)
                     /locus_tag="VXB71_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0450194.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWENYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(9779..10429)
                     /locus_tag="VXB71_000011"
     CDS             complement(9779..10429)
                     /locus_tag="VXB71_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0450195.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEILE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            10541..11383
                     /locus_tag="VXB71_000012"
     CDS             10541..11383
                     /locus_tag="VXB71_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0450196.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            11459..11896
                     /locus_tag="VXB71_000013"
     CDS             11459..11896
                     /locus_tag="VXB71_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0450197.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            11964..12266
                     /locus_tag="VXB71_000014"
     CDS             11964..12266
                     /locus_tag="VXB71_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450198.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(12357..13430)
                     /locus_tag="VXB71_000015"
     CDS             complement(12357..13430)
                     /locus_tag="VXB71_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0450199.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            13586..14263
                     /locus_tag="VXB71_000016"
     CDS             13586..14263
                     /locus_tag="VXB71_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450200.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            14256..15230
                     /locus_tag="VXB71_000017"
     CDS             14256..15230
                     /locus_tag="VXB71_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0450201.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(15279..17222)
                     /gene="thrS"
                     /locus_tag="VXB71_000018"
     CDS             complement(15279..17222)
                     /gene="thrS"
                     /locus_tag="VXB71_000018"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0450202.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(17280..17603)
                     /locus_tag="VXB71_000019"
     CDS             complement(17280..17603)
                     /locus_tag="VXB71_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0450203.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(18034..18234)
                     /locus_tag="VXB71_000020"
     CDS             complement(18034..18234)
                     /locus_tag="VXB71_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450204.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            18472..19101
                     /locus_tag="VXB71_000021"
     CDS             18472..19101
                     /locus_tag="VXB71_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0450205.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            19242..19511
                     /gene="rpsO"
                     /locus_tag="VXB71_000022"
     CDS             19242..19511
                     /gene="rpsO"
                     /locus_tag="VXB71_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0450206.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            20326..20940
                     /locus_tag="VXB71_000023"
     CDS             20326..20940
                     /locus_tag="VXB71_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0450207.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(21232..21981)
                     /locus_tag="VXB71_000024"
     CDS             complement(21232..21981)
                     /locus_tag="VXB71_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0450208.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            22114..24450
                     /locus_tag="VXB71_000025"
     CDS             22114..24450
                     /locus_tag="VXB71_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV0450209.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLMETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDSIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            24552..25229
                     /locus_tag="VXB71_000026"
     CDS             24552..25229
                     /locus_tag="VXB71_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0450210.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            25216..26013
                     /locus_tag="VXB71_000027"
     CDS             25216..26013
                     /locus_tag="VXB71_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0450211.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            26030..27133
                     /locus_tag="VXB71_000028"
     CDS             26030..27133
                     /locus_tag="VXB71_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0450212.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            27434..28453
                     /gene="galE"
                     /locus_tag="VXB71_000029"
     CDS             27434..28453
                     /gene="galE"
                     /locus_tag="VXB71_000029"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0450213.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            28455..29408
                     /locus_tag="VXB71_000030"
     CDS             28455..29408
                     /locus_tag="VXB71_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0450214.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(29470..29676)
                     /locus_tag="VXB71_000031"
     CDS             complement(29470..29676)
                     /locus_tag="VXB71_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0450215.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            29729..30205
                     /locus_tag="VXB71_000032"
     CDS             29729..30205
                     /locus_tag="VXB71_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0450216.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            30214..30885
                     /locus_tag="VXB71_000033"
     CDS             30214..30885
                     /locus_tag="VXB71_000033"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0450217.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEDLLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            31016..31354
                     /locus_tag="VXB71_000034"
     CDS             31016..31354
                     /locus_tag="VXB71_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0450218.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            31357..31986
                     /locus_tag="VXB71_000035"
     CDS             31357..31986
                     /locus_tag="VXB71_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0450219.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            32226..33377
                     /locus_tag="VXB71_000036"
     CDS             32226..33377
                     /locus_tag="VXB71_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0450220.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            33690..34439
                     /gene="truA"
                     /locus_tag="VXB71_000037"
     CDS             33690..34439
                     /gene="truA"
                     /locus_tag="VXB71_000037"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0450221.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            34429..35202
                     /locus_tag="VXB71_000038"
     CDS             34429..35202
                     /locus_tag="VXB71_000038"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0450222.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            35180..35641
                     /locus_tag="VXB71_000039"
     CDS             35180..35641
                     /locus_tag="VXB71_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0450223.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35868..37209
                     /locus_tag="VXB71_000040"
                     /pseudo
     CDS             35868..37209
                     /locus_tag="VXB71_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(37337..37540)
                     /locus_tag="VXB71_000041"
     CDS             complement(37337..37540)
                     /locus_tag="VXB71_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450224.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(37533..38615)
                     /locus_tag="VXB71_000042"
     CDS             complement(37533..38615)
                     /locus_tag="VXB71_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0450225.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(38741..39523)
                     /locus_tag="VXB71_000043"
     CDS             complement(38741..39523)
                     /locus_tag="VXB71_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0450226.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(39523..40866)
                     /locus_tag="VXB71_000044"
     CDS             complement(39523..40866)
                     /locus_tag="VXB71_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0450227.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(40965..42281)
                     /locus_tag="VXB71_000045"
     CDS             complement(40965..42281)
                     /locus_tag="VXB71_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0450228.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            42474..43700
                     /locus_tag="VXB71_000046"
     CDS             42474..43700
                     /locus_tag="VXB71_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0450229.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            43899..45473
                     /locus_tag="VXB71_000047"
     CDS             43899..45473
                     /locus_tag="VXB71_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0450230.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            45738..46526
                     /gene="codY"
                     /locus_tag="VXB71_000048"
     CDS             45738..46526
                     /gene="codY"
                     /locus_tag="VXB71_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0450231.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            46526..47101
                     /locus_tag="VXB71_000049"
     CDS             46526..47101
                     /locus_tag="VXB71_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0450232.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            47183..47268
                     /locus_tag="VXB71_000050"
     tRNA            47183..47268
                     /locus_tag="VXB71_000050"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47217..47219,aa:Leu,seq:aag)
     gene            47551..48681
                     /gene="ugpC"
                     /locus_tag="VXB71_000051"
     CDS             47551..48681
                     /gene="ugpC"
                     /locus_tag="VXB71_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0450233.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            49182..49940
                     /locus_tag="VXB71_000052"
     CDS             49182..49940
                     /locus_tag="VXB71_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0450234.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            50028..50540
                     /locus_tag="VXB71_000053"
     CDS             50028..50540
                     /locus_tag="VXB71_000053"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0450235.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            50722..51666
                     /locus_tag="VXB71_000054"
     CDS             50722..51666
                     /locus_tag="VXB71_000054"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0450236.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            51675..52352
                     /locus_tag="VXB71_000055"
     CDS             51675..52352
                     /locus_tag="VXB71_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0450237.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            52450..53208
                     /locus_tag="VXB71_000056"
     CDS             52450..53208
                     /locus_tag="VXB71_000056"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0450238.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            53246..54751
                     /gene="lytC"
                     /locus_tag="VXB71_000057"
     CDS             53246..54751
                     /gene="lytC"
                     /locus_tag="VXB71_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0450239.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            55249..55767
                     /locus_tag="VXB71_000058"
     CDS             55249..55767
                     /locus_tag="VXB71_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0450240.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            55897..56403
                     /locus_tag="VXB71_000059"
     CDS             55897..56403
                     /locus_tag="VXB71_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0450241.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            56403..56573
                     /locus_tag="VXB71_000060"
     CDS             56403..56573
                     /locus_tag="VXB71_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450242.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            56605..57837
                     /gene="clpX"
                     /locus_tag="VXB71_000061"
     CDS             56605..57837
                     /gene="clpX"
                     /locus_tag="VXB71_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0450243.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            57846..58433
                     /locus_tag="VXB71_000062"
     CDS             57846..58433
                     /locus_tag="VXB71_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0450244.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHAPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            58444..58824
                     /locus_tag="VXB71_000063"
     CDS             58444..58824
                     /locus_tag="VXB71_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0450245.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            58876..59766
                     /gene="rapZ"
                     /locus_tag="VXB71_000064"
     CDS             58876..59766
                     /gene="rapZ"
                     /locus_tag="VXB71_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0450246.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            59763..60740
                     /locus_tag="VXB71_000065"
     CDS             59763..60740
                     /locus_tag="VXB71_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0450247.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            60737..61648
                     /gene="whiA"
                     /locus_tag="VXB71_000066"
     CDS             60737..61648
                     /gene="whiA"
                     /locus_tag="VXB71_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0450248.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(61682..62650)
                     /locus_tag="VXB71_000067"
     CDS             complement(61682..62650)
                     /locus_tag="VXB71_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0450249.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQTLQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            62786..63643
                     /locus_tag="VXB71_000068"
     CDS             62786..63643
                     /locus_tag="VXB71_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0450250.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            63630..64409
                     /locus_tag="VXB71_000069"
     CDS             63630..64409
                     /locus_tag="VXB71_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0450251.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            64433..65785
                     /locus_tag="VXB71_000070"
     CDS             64433..65785
                     /locus_tag="VXB71_000070"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0450252.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            65859..66233
                     /locus_tag="VXB71_000071"
     CDS             65859..66233
                     /locus_tag="VXB71_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0450253.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            66235..67083
                     /locus_tag="VXB71_000072"
     CDS             66235..67083
                     /locus_tag="VXB71_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0450254.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            67360..68127
                     /locus_tag="VXB71_000073"
     CDS             67360..68127
                     /locus_tag="VXB71_000073"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0450255.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            68139..69323
                     /locus_tag="VXB71_000074"
     CDS             68139..69323
                     /locus_tag="VXB71_000074"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0450256.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            69320..71191
                     /locus_tag="VXB71_000075"
     CDS             69320..71191
                     /locus_tag="VXB71_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0450257.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAQDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(71334..72518)
                     /gene="mntE"
                     /locus_tag="VXB71_000076"
     CDS             complement(71334..72518)
                     /gene="mntE"
                     /locus_tag="VXB71_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0450258.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            72822..75518
                     /locus_tag="VXB71_000077"
     CDS             72822..75518
                     /locus_tag="VXB71_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0450259.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            75531..76322
                     /gene="yghU"
                     /locus_tag="VXB71_000078"
     CDS             75531..76322
                     /gene="yghU"
                     /locus_tag="VXB71_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0450260.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLRTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            76438..76848
                     /locus_tag="VXB71_000079"
     CDS             76438..76848
                     /locus_tag="VXB71_000079"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0450261.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            76860..78455
                     /locus_tag="VXB71_000080"
     CDS             76860..78455
                     /locus_tag="VXB71_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450262.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGRTFEGQVGKDSYLKTFKVQ"
     gene            78634..78798
                     /locus_tag="VXB71_000081"
     CDS             78634..78798
                     /locus_tag="VXB71_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0450263.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKENKDKFLSILTSLAGLALV
                     LVAVWLGWPK"
     gene            78877..79605
                     /gene="yaaA"
                     /locus_tag="VXB71_000082"
     CDS             78877..79605
                     /gene="yaaA"
                     /locus_tag="VXB71_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0450264.1"
                     /translation="MKILIPTAKEMNTDLPSIETTLLRSESQAVLDALALYSASQLES
                     FYKVSAEKAAEECQNIQALKRQTAQHYPALKLFDGLMYRHIKRDKLTEVEQAYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDEAVKQEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(79656..81140)
                     /locus_tag="VXB71_000083"
     CDS             complement(79656..81140)
                     /locus_tag="VXB71_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0450265.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            81356..>83226
                     /locus_tag="VXB71_000084"
     CDS             81356..>83226
                     /locus_tag="VXB71_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0450266.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETK
                     PAVTTTERSAVDSAILPISTAAKVETTSAPASTNEILKPSLSLSDARQNPAIRKEDVD
                     RGYSGFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGLHSFRGIGHSRGG
                     REIHYDVTTVRRGNRLNFTIKYSGPGEFVNNNFILDKGDGFGNPSNATITSSNPRVRE
                     QSKSISQGANYVSHSGYSMTSATSTNTEQTIRFSLPIINPNGDLSVRLKPVTFNVDQG
                     GGGAATSNDPYSNSNYYHRANPLLLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQ
                     TRLVREGEKGQRQITYKVHRFGNETLLGLPISNRVTKEAKPRIMQIGVAKELIDTVKP
                     RVDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGA"
BASE COUNT        24590 a        15397 c        18868 g        24371 t
ORIGIN      
        1 cattccctag tgatttttgt taagataaat gcaaatacaa atgaaagcga gaacaagatg
       61 acacgttatc aagatgattt ttatgatgct atcaatggaa aatggcaaca gacagctgaa
      121 atcccagcag ataagtctca aacaggaggt tttgttgatt tagaccagga aattgaagac
      181 ctgatgctgg cgacaacaga caagtggtta gcaggtgaag aagtgcctga ggatgctatc
      241 ttggaaaact ttgtcaaata ccaccgccta gttcgtgatt ttgacaagag agaagctgac
      301 ggtatcacac ctgtcttacc actccttaaa gaattccaag aattggaaac ttttgcggat
      361 tttacagcta aactagcaga gtttgagctt gcaggaaaac caaacttcct tccttttggt
      421 gtatcgccag actttatgga tgctagaatc aatgttctat gggctagcgc tccaagcaca
      481 atcttgccag atacgaccta ctatgcagaa gaacatcctc agcgcgaaga gctcttgact
      541 ctttggaaag aaagcagcgc aaatctcctc aaggcttatg atttctctga tgaagaaatt
      601 gaagacttgc tagaaaaaag acttgaattg gaccgccgag ttgcggcagt ggtgctctct
      661 aatgaagaaa gttcagaata tgctaaactc tatcatccat attcttacga agatttcaag
      721 aaattcgcgc ctgccctacc tttggatgac ttcttcaaag cagttattgg gcaattacca
      781 gacaaggtta ttgtagacga ggaacgtttc tggcaagcag cagagcaatt ttacagtgag
      841 gaagcctggt ctctccttaa agcaaccttg attttgagtg ttgtcaatct ttcaaccagc
      901 tatttaacag aggatatccg tgttttgtct ggtgcctaca gccgtgccct ttctggagtt
      961 ccagaggcaa aagataaggt caaagcagct tatcatctag cacaggaacc tttcaagcaa
     1021 gccctggggc tttggtacgc ccgtgagaag ttctctccag aagccaaggc ggatgtggag
     1081 aaaaaagtgg caaccatgat tgatgtctat aaggagcgtc tgcttaagaa tgactggctc
     1141 actccagaaa cctgtaaaca ggctatcgtg aagctcaatg tgatcaaacc ttatattggc
     1201 tatccagaag aattgcctgc acgttacaag gataaggtag tgaatgaaac tgccagtctt
     1261 tttgagaatg ctctagcctt tgcgcgtgtg gaaatcaagc acagttggag taagtggaac
     1321 cagcctgtag actataagga atggggcatg cctgctcata tggtcaatgc ctactacaat
     1381 cctcagaaga acctgattgt ctttccagcg gccattttac aggcgccttt ctatgacttg
     1441 catcagtcat cttctgctaa ctacggtggt attggggcag tgattgccca tgaaatttcc
     1501 cacgcctttg atactaacgg ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg
     1561 acagagagcg actatgctgc cttcaaggag aaaacacaaa aagtcattga ccaatttgat
     1621 ggacaggatt cttatggagc aaccattaac ggtaaattga ctgtatcaga aaacgtggct
     1681 gacttgggag gaatcgcagc agcgcttgaa gcagctaaga gagaagcaga cttctcagca
     1741 gaagagttct tctacaactt cggtcgcatc tggcgcatga aaggtcgacc agaatttatg
     1801 aaacttttgg ctagcgtcga tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta
     1861 ccaaacttcg acgatttctt tacaacctat gatgtcaaag aaggagacgg aatgtggcgt
     1921 tcaccagagg agcgcgtgat tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc
     1981 atccaatcac gtgtgaaaac cttgatagga tgccttttgt aatagaaaga tttgctggat
     2041 agtttactta aatttcgatt gtcatcatct tgctagaaaa agggattgaa ggccttttcg
     2101 tgagcgatag tagtagctgg accatgtcct ggatagacat cgtagtttgg tagggtgaag
     2161 agttgggtct ggatactatg aaggagttgc tccatgctac cagtcggaag gtcggtccgt
     2221 ccgatagttt cgcggaatag agcatctccc gtcaagacta ggtgagcatc aggaaagact
     2281 agggaaacac caccgataga gtgccctggg gtcggtagaa ccttaaaacg aaattcctct
     2341 agttggtatt cttcgtgaaa gacaaaggtg tgttctgcag gttttgtgac cacatctgcc
     2401 atatcatcgt ggcgagggag accggagaga ttatcgacag gagtgtagag ccagctggct
     2461 tcgctctctg cgatatagac aggaggattg ccaaacgtct cgcgaaccaa gtccagactc
     2521 atgatatggt cataatgggc gtgggtcaag agaatagcac agatcggttt gttgatcttc
     2581 tcgattgtct gacgaatggc ttcccaatga ctaccaggat cgacgacgat gaggtgcttt
     2641 tcgccttcta gataataggt attttcatag gcaacaggat tcacggtttt atggattttc
     2701 atactaactc caatctcaaa gaatgtacta atactcttcg aaaatctctt caaaccgcgt
     2761 caactttatc tgcaacctca aagcagtgct ttgaacagcc tgcggctagc tttctagttt
     2821 gctctttgat tttcattgag tataaattaa gtatagcaca gttagggaga ataggtaagg
     2881 atttaaaatg aacttaaaaa ccagcatgac tagatgaaga caggctggtt atcaatttat
     2941 caatattgga aaggtgtcaa ttgcccttca taggttgcat aaactccgtc attagcttgt
     3001 ttgatagacg tgatgtttag agtgctaccg tagttggctt ctcatttgtc gctatattca
     3061 ctataagtta tcctactggg caggttctgg tcgttagcat agtattgaac gagtttttta
     3121 tagctttgct ggctgaatag gaacaggcag caaactccta acattaggag agcaaagata
     3181 gaaatagcag ttttttcata ggtattctcc ttataaacta aaggatagaa gaaagtatct
     3241 tgaggatttt tatactcttc aaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat
     3301 atatgtgact gactttgtca gtcttatcta caacctcaaa gcagtgcttt gagcaacctg
     3361 tggctagttt cctagtttgc tctttgattt tcattgagta ttaattccaa aatccagtca
     3421 aggtaccagt gtatgtgata cgagttccac cgtttatctt tcgtatcttc aatggaattg
     3481 gggaaatcag aaagtctttg ggttacaata tggtttccgt tcttctatct ctccttctat
     3541 cacctaagtt taaaatctaa cttcgtagta tattatgggc caataattca gaattatcaa
     3601 gcaattttga attatttttt tcttattctg ttccaatcta gttttcatat tcttaaaaaa
     3661 gtgataaaat ggtaggaaga attggagagt agagatgccg aaagaagtga atttaacagg
     3721 cgaagaagtt gtcgctttaa ccaaagaata tttaacggaa gaggatgttc attttgtcca
     3781 taaggccttg gtctatgctg ttgaatgcca cagtggtcaa tatcgcaaat caggcgagcc
     3841 ttatatcatt caccctatcc aagtggcagg tattttagct aagctaaagc tggatgctgt
     3901 aacagtagct tgtggattct tgcatgatgt ggtggaagat acagatgcga ccttggacga
     3961 tttggaaaga gagtttggtc ctgatgtgcg ggtgattgtt gacggagtta ccaagcttgg
     4021 caaggtcgag tacaaatcga tcgaggagca attagcggaa aatcatcgca agatgctcat
     4081 ggccatgtct gaggacatcc gcgttatttt ggtcaaactg tctgaccgct tgcacaatat
     4141 gcggaccctg aaacatcttc gaaaagacaa gcaggagcgt atttccaaag aaaccatgga
     4201 aatctatgcc ccacttgccc atcgtttggg gatttccagt gtcaaatggg aattagaaga
     4261 cttgtctttc cgttatctca atccaacgga gttttacaag attacccata tgatgaagga
     4321 aaagcgcagg gagcgtgagg ccttggtgga tgaggtagtc acaaaattag aggagtatac
     4381 gacagaacgt cacttgaaag ggaagattta tggtcgtccc aagcatattt actcaatttt
     4441 ccgcaaaatg caggacaaga gaaaacggtt tgaggaaatc tatgatctga ttgctattcg
     4501 ttgtatttta gatacccaaa gtgatgttta tgccatgctt ggttacgtgc atgaattttg
     4561 gaaaccgatg ccaggtcgct tcaaagacta tattgccaac cgcaaggcca atggttatca
     4621 gtctatccat acgactgttt atggaccaaa agggccgatt gaattccaga ttcgaaccaa
     4681 ggaaatgcac gaggtggctg agtacggggt tgcggctcac tgggcttata agaaaggtat
     4741 aaaggggcaa gttaacagca aggaatcagc tattggaatg aactggatca aggagatgat
     4801 ggagctccaa gaccaggctg atgatgctaa ggaatttgtg gactctgtta aggaaaacta
     4861 tttggctgag gagatttacg tttttacccc agatggagct gtccgttccc ttcccaaaga
     4921 ttcaggaccg attgattttg cctacgaaat ccataccaag gtcggtgaaa aagcaactgg
     4981 tgccaaggtc aatggccgca tggttccact gacaaccaag ttaaagacag gggatcaggt
     5041 tgaaattatc gccaacccga actcctttgg acctagccgt gactggctca atatggtcaa
     5101 gactagcaag gcgcgcaata agattcgcca gttctttaaa aaccaagata aggaattgtc
     5161 tgtcaacaag ggtcgtgaga tgctgatggc tcagttccaa gaaaatggct atgtggcaaa
     5221 taaatttatg gacaagcgcc acatggatca agttctgcaa aagaccagtt acaagacaga
     5281 agactccctc tttgcggcca ttggttttgg ggaaatcggt gcgattaccg tctttaaccg
     5341 tctgactgaa aaggaacgcc gtgaggaaga gcgtgccaag gccaaggctg aggcagagga
     5401 gcttgtcaaa ggtggcgagg tcaaggttga aaataaagaa actctcaagg tcaagcatga
     5461 ggggggagtg gttattgaag gtgcttctgg tctcctagtg cggattgcta agtgttgtaa
     5521 ccccgtgcct ggtgacgata ttgttggcta cattaccaag ggtcgtggtg tggctattca
     5581 ccgtgtggac tgtatgaacc tgcgtgccca agaaaactac gagcaacgtc tccttgatgt
     5641 ggaatgggaa gaccagtact ctagctcaaa taaggagtat atggcccata tcgatatcta
     5701 cggtctcaac cgtacaggac tgttgaacga tgtactgcaa gttctttcaa atacaaccaa
     5761 gaatatttca acggtcaatg cccaaccaac caaggatatg aagtttgcta atatccatgt
     5821 gtccttcggt attgccaacc tctctacact gaccacggtt gtcgataaaa ttaagagtgt
     5881 gccagaagtt tactctgtca aacggaccaa cggctagttg tcctagctct tactagaaag
     5941 gctattatga aaatcattat ccaacgggtt aaaaaagccc aagtgagtat agaaggccag
     6001 attcagggaa aaatcaatca gggactttta ttgctggttg gtgttggacc agaggaccaa
     6061 gaggaagatt tggactatgc tgtgagaaaa ctggtcaata tgcggatttt ttcagacgca
     6121 gaaggcaaga tgaacctgtc tgtcaaagat attgaaggag aaatcctctc catttctcag
     6181 tttaccctct ttgcggatac taagaaaggc aatcgtccag cctttacagg ggcagctaaa
     6241 cctgatatgg catcagactt ctatgatgct ttcaatcaaa aattagcgca agaagtgccc
     6301 gttcagacag gtatctttgg agcagatatg caggttgagc tggttaataa cggacctgtt
     6361 accattatcc tagatactaa aaagagataa gaaagaccaa gcccagtcgg cttggtcttt
     6421 ctcatcgatc ataaaatact ccaaaaagaa atcggttctt gatatgcttg ggggaagtct
     6481 cttttcaggc tttggcagat gcgataggaa gggatgagat gtcctaggat gaggagagtt
     6541 ccctgaagga aaagtggaat atcacttaaa gacaccaagg agagaatcat caggctatcc
     6601 cataggaaaa tttgtaaagc aaaacgccag aatctcggtc taatctggga atagagttga
     6661 ctaaagtggt cacaaagttg gtttgaaaga taggtcaata gcacgggatg aaagaaaatg
     6721 agccaaccac tataaatcaa aatccagtcc caagtaagcc ccccttttaa atgtcaaaaa
     6781 taccagcatg attccatcaa tgacaaggag ttgaatggtt ttgatgaaga tgattttttt
     6841 catgctaaaa cctccttttc cttagagaca ctcccctaca ggtattttag aatgtatatt
     6901 gcttagatat tccttatttt attagctttt taaggtatta aagtagttat ataagtttat
     6961 gaagggtatc ctatcctgca cggctaattt tgagttcgaa actgaggagt ttataactca
     7021 aaatttcgat taaatcagca tttaacgata gtatgtttgt cataaaatga taaattttta
     7081 gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt atatacttaa
     7141 tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag agaatgttag
     7201 aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg atgtttacaa
     7261 taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta gagaatacgt
     7321 tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac ctttttcatc
     7381 gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga aagatgtatt
     7441 aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga aacgtataca
     7501 tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta ataatgattc
     7561 ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac ctattacggg
     7621 ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta atattgttta
     7681 gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt ttatgaggaa
     7741 ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga taattaaatc
     7801 atctccatag tttctgagaa taattgagaa actatactct aaatcatagg tttatgtaaa
     7861 gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc accgttgaat
     7921 tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa aatgaataga
     7981 aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta tatagacaag
     8041 gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga tttggaagat
     8101 attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag actggatgtg
     8161 atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc tacgattttt
     8221 ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta atataaggga
     8281 ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat gaaagttaat
     8341 gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat aaaatagtat
     8401 acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg tagtcagctg
     8461 tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat gaaaaacgct
     8521 gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga acccctaaat
     8581 agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga tgtttgagtc
     8641 ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa ccagagagca
     8701 agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt agcaaatcaa
     8761 taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga cctccctctt
     8821 ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga taaaaatagc
     8881 agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt ctattatcta
     8941 acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata aaagatgtat
     9001 ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac gaaattgtaa
     9061 atcaaccaaa agccccactg agttgttagt tttaatgcat tcaaagcatt ggcaatgagg
     9121 gacagtgcaa aggcaatagt tgttacgtag gcaaggagat tcatcttgcc cccatatccg
     9181 atatagttgg tcacaaaggc aaagaggaag gcgatgatgg aaatgatgat ggccgccaat
     9241 tttacctgtt tttggctcat ttggttgggt ctgccttctt gcgaagcttt ccatttcttt
     9301 atagcaaagg tataaatgag gaaggtgacg ggataggtaa tgatggccgc cttatttcca
     9361 aggatataat caatagcacc ggacaaaatg gtattaacaa taccaaagta attttcccat
     9421 ttgcttaatt tccccgtgaa acgagtggac aacatggaaa tcccaacgtt ggttacggaa
     9481 atcaatccaa agggtacaag agctgtccat ggtccccagt ctacaaattt atcgaggcgt
     9541 gagttgaggt aaccagatgc aatcgcaatc caacgaccaa agcaaccccg aagaggtcaa
     9601 actatttaga tgtagcaaaa atttttagtg attttttcat aggttaaact acctttcttt
     9661 ttttcaaata ttctcccatt ttttttcaaa tattctacca ccaaatgaaa gtaaaataaa
     9721 atgatagaaa taaaaccctg aaaataaaac tttcagggtt ggtaggggac ttgagaaatt
     9781 agttgatttt ctcgacatag agttgttttg caatgtccat attcacttgt aaatcctcgt
     9841 cgttactgag gatagtgaag gtattgctga agccatcaaa ctgcttaact tggagctggt
     9901 caccgatgtg aagtgagtgc ttgtccagat aatggagaat gtcaaaacta tcgtgcatcc
     9961 gagtcaggcg gtaggcgcca gcttccttga tatcagctag tgggaggtta ttgatttcaa
    10021 cgaggagttc tcccttggca ggaatagttc ctccgtgggg gcaggtttta gggaaaccta
    10081 gcagtttatc tagtctttcc acgaacaggt cagagacagt gtgttccaag atctcagctt
    10141 cctcgtgaat ctggtcactt gtatagtcta aatgatgaac tagaaaaact tcaatcaagc
    10201 ggtgcttacg atagagctca gagaccagtt tgagaccgag gtcagtcagt agatagccac
    10261 attccttgtc ctttaggatg agattttcac ttttcattcg tttgatcatt tcagttacgg
    10321 cagggggaga gacttgcatg cgagccgcaa tttccttgtt ggtaatctta tgcaggtcta
    10381 tgccaatttc ataaatacat tttagatagt cttctttgtt tggggtcatt cgtttcctct
    10441 tgtctaatat ctttatctag tatatcaaaa aaagctagat ttctctagct gtgacttttt
    10501 atgttatact tattgcaaga gaaaaaacga ggagatggat atgacgaaaa tagctcttct
    10561 ttcagatatt catggaaata ccaccgcctt ggaggctgtt ttggcagatg ctcggcagct
    10621 aggagtggat gaatactggc ttttgggaga tattctcatg ccagggacag ggcgtagaag
    10681 gattttggac ttgttggatc aactaccgat tacggctaga gttttgggaa actgggaaga
    10741 cagtctttgg catggtgtcc gtaaggaatt ggatagtact cgccctagtc aacgctatct
    10801 cttgcgccag tgccagtatg ttttagagga aatttcccta gaagaaattg aagtgctcca
    10861 caatcaacct cttcaaattc atcgtcagtt tggggatttg acagtgggaa ttagccatca
    10921 tctgcctgat aagaactggg ggcgagagtt gattcatact ggcaaacaag aggaatttga
    10981 ccgcttggtg actcatcctc cctgtgatat tgctgtttat ggacacattc accagcagtt
    11041 gcttcgttac gggactggtg ggcaattgat tgtcaatccg ggttcgattg gccaaccttt
    11101 ctttttggac gctcagctac ggaaggactt gcgggcccag tatatgattt tggagtttga
    11161 tgacaagggc ctggtagata tggacttccg acgggtagat tacgatgtgg cagctgaatt
    11221 gcagctggct aaagacctga gacttcccta ttttgaggtt tactatgaaa gtctggtcaa
    11281 tgggatccac catactcatc atcaggaatt tttgagagaa ttggctcaga aagagggttg
    11341 cgatcgggag ttagacgact ggttgaaaag tggtaacgat tgacattaca actaaaaagg
    11401 gtataataat agaaaaagaa gagtagaggc agggtagcct cgtaaaaagg agaagaggat
    11461 gcaaattcca agtagattta ccattgcgac tcatatgctg ataatcattg ccctcgaggg
    11521 gaagaaaagc aaggtgacca gtgattttct ggctgctagt gtcggggtca atcctgtcat
    11581 tatcagaaag atcttgtccc agttgaagaa ggcagagctg atttcagtag cgcgtggaac
    11641 gggcggaaca gatattgtca aggaccttaa ggatattagt cttttagatg tttatcaggc
    11701 ggtcgaatgt cttggtaaga caggtcaact cttcagtttc catgacaatc cgaatccaaa
    11761 ttgccctgta ggagctcata ttcatgatgt tttggatcaa aaattggaga gaattcagtt
    11821 gactatggag gcagaacttg gtcaaaccag tctagaaaaa gtcgtggccg atgcagagag
    11881 tcagatgaag gattaagagg gataaatgcc ctcttttttc tttggataat tatgataaaa
    11941 tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg aattgtatta gcctttatag
    12001 tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta ttatccctca
    12061 tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag aatgttcagt
    12121 tagcttttta tgtatttgcc tttgtcttac ttcctttttt gctttttcta agtggcatct
    12181 ttttaatcta taatggggtc attttgttga agcgagaggg acgttccaag ccccattatc
    12241 tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac ttagaatgca
    12301 catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca agagtattat
    12361 ctatttttcc atgcctggta acgagtatca atcaataact gggtaaggcg acccaaggtt
    12421 tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat gtattcaagc
    12481 gcctttaagg aagccaagtc attgatagag ctaataccag cctcaagaat agtgccaaag
    12541 aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca ttctttaaag
    12601 gttgtgtcta cttgctggct atcactgttg gtcttatcca gttggacgaa gtgcttgtcc
    12661 tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt actctgaacg
    12721 atgatttggt gagcaggaat ttccagcatc ataccgataa tggaaccttg tggaatgaat
    12781 atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc ttgatggaga
    12841 ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg ctcaatttgg
    12901 ctagcagcat agatagcgag atttcctccc ttggaatgcc cagctagaat aaccttttgc
    12961 ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg agcaggaatt
    13021 tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc atctgtccca
    13081 cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc aaattgcttt
    13141 tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt gaagcgcttg
    13201 tgttgagcca atttatctaa taattgaagg cgatttttgc tagtaagcat ggtgggctct
    13261 cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac cagattatca
    13321 aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa gggaaggtcg
    13381 taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat aagagctcct
    13441 ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag cctgtttgca
    13501 ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg aaaaatctgt
    13561 tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag atgatcaggt
    13621 cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg tcctggtaga
    13681 agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg tcctcatgga
    13741 tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca agatttccaa
    13801 ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca tggcaatcaa
    13861 tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt tagctaaggt
    13921 tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc tggaatatgc
    13981 tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag tcttgaattt
    14041 gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca acatcgtagc
    14101 acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg ataataccct
    14161 ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg taggatttat
    14221 cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa caattttttc
    14281 tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttctttg gcatttcttg
    14341 tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac tttttcttct
    14401 tgtgttgctt tgtaaccatc ttatttttca cttgggacat attggtggaa atgcaggtct
    14461 atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa atagctttag
    14521 cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa gcagaaagaa
    14581 aactgacgga tttgctggat tactatacct tgtgggtcca tcagataaag acccccattg
    14641 cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag cagctagaac
    14701 aggaaatttt caaaatcgac tcttatacca acctagtttt acagtacctg cgtttagaaa
    14761 gtttccatga tgatttggtc ttaaagcagg ttcaaattga ggacttggtc aaggaaataa
    14821 ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta catgaccttg
    14881 ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa atcatctcaa
    14941 acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac caagagcttt
    15001 gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta tttgaacgtg
    15061 gcttttcagg atacaatggc cgtttgaccc agcagtcctc tggacttggc ctttatctat
    15121 ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag gtcggaaaag
    15181 gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa aaatagatga
    15241 gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac gcgtgatttg
    15301 ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt ttgtgtttct
    15361 ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc tccaacaatt
    15421 aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat tttttcattg
    15481 cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggctac ttcccaagcg
    15541 tagtccacgt gtttttcgtt agatactggg ataagggtta cttggtgtgg tgccagccat
    15601 gttgggaagg cacccttgta gttctcaatc aagatagctg tgaagcgttc catagttgag
    15661 ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc gatgtatttg
    15721 aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt ttcttctttt
    15781 ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggccgc ttcaccttcg
    15841 gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt ttgggcattt
    15901 tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg aagagagagg
    15961 cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa ctgaagggca
    16021 cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc gttgagtgac
    16081 atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg gtgcatcata
    16141 ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg tttgaaaact
    16201 tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc acccatgtcc
    16261 atggttggga acatgtcttc ttggtaatga tcccagtggc cagaagtctt gtaaagctca
    16321 acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc tttgtttacg
    16381 atgtagcgtt ccaattcacg acggatagtc gcaccatttg gcaaccagaa tggcaaacct
    16441 tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt acggtggtca
    16501 cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt ttcaaaccaa
    16561 gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca gtacgcacca
    16621 gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacgtg aggtccacgg
    16681 cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc ttctgagtgt
    16741 tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc ctcgtcttta
    16801 gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat ttcttcttcg
    16861 atacgaggaa ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc gtagtagaaa
    16921 ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg acgagctgct
    16981 tgggcgaaca agtgagctgc tgagtggcgc aagattggaa gggcatcttc gtgatcaggt
    17041 gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat gagtttgccg
    17101 ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg ggcaatttca
    17161 aaagttgtta cgccagattc gaattcacga acagcgccat ctgggaaagt aatgttaatc
    17221 atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt atcatcagac
    17281 tacttccaag tcctaacgtt caattgcttt tctttatcag agaggaagtt ttccatttcc
    17341 gtcagaatgt ctatatccaa acgttgagaa agttctaata gccaccagat attttctgaa
    17401 agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt tgtcatcacc
    17461 agtcgttgga aatttccaat atcattagat aaagccaagg ggtcttcttc taccgtccac
    17521 ttggaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc ccaactgcgc
    17581 tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga catcctcgaa
    17641 aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg gacacctctg
    17701 attggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag tagtatcagt
    17761 ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg actaagtgac
    17821 ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt gtgaaagttt
    17881 tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca tgcccaccag
    17941 agcaactgtt tcatagatta gcaagtaaat tagtataaac tcaccaaagg ttatgatagt
    18001 aaagtaaaag agcagtccgt taccaactaa ccatcaaagt gagaaacgga aacggtagct
    18061 atagagtaac gatacaatca agattaccag aggtgtaaag aagagaagat tgtttatata
    18121 gagttccttg agtgtaaggg ggtcagaaac aactagtaag aacaactcat aaagtggcca
    18181 ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac gcatgataat
    18241 cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta tagcatgttt
    18301 aaaacaagaa agtaaatttg ttggcaaaga agattttttt ttcactagaa tcatggttag
    18361 ttttcttggt agaaatattt tgataataat taagcaaaac tattgacatt gattattaag
    18421 agtgtcacaa ttgttgtaac taaaataatt acaataagag aggtataaaa aatgaaacta
    18481 gcagttattg cagcaaatgg acaagcgggg aaagcaattg ttgaagaagt agtcaaacga
    18541 ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaatctga gtctattatt
    18601 aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc tgttatttca
    18661 gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat cgaactattt
    18721 aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggagc aggaagtctt
    18781 tatatagatg aaacaaaaac gacacgactt ttagatacgt ctgattttcc tgaagaattt
    18841 aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa aaataatctc
    18901 aactggactt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa aacaggaaac
    18961 tacattctag caggagaaat ttttactact aatgaaaaag gaataagcca gattagttat
    19021 gcagattatg ctattggatt ggtagatgaa cttgaaaaag gtcatcatat aaaagaacgt
    19081 atctctttac ttgaaaaata ataactatga gagtattaat gtttgacaga aaatttaaat
    19141 cttggtaaaa tagggattgt cgtaaagaca aataacttct tcttggttac aggcatgcca
    19201 acctgtcact cggatgaagc caaataaaaa ggagaaacat catggcaatc tcaaaagaga
    19261 aaaaaaatga aatcattgca caatatgcac gtcacgaagg tgatacaggt tcagtagagg
    19321 ttcaagttgc tgtccttact tgggaaatca accaccttaa cgaacacatc aaacaacaca
    19381 aaaaagacca cgctacttac cgtggattga tgaaaaaaat cggtcgccgt cgtaacttgc
    19441 ttgcatactt gcgtaaaaac gacgttaacc gttaccgtga gttgatcaac tctctaggac
    19501 ttcgtcgcta attcaagata caaaggccgt caaaaacaca aagcaaaaat aggaaaattg
    19561 acgaagaaac ttcagtttct aggagatttt atcttttttg ccaagtgctt aggccgtgtt
    19621 caattgagca tatcttgata ataaagctac tctaaattgg gtagctttgt tgcgttgtca
    19681 ccttacctcg ctatactcaa gtataatctt cggttacggt tcctagcact gtaaggtaaa
    19741 ataaactagc ttttctccct tcggggagat ttttttgttt cactgaaagt ttcgtacgat
    19801 cttcacctcg tcccctagtc tataaacgat ttatctagca agaatcatga tgctaagggc
    19861 gtcaaaaatc cgtatgaaaa tagggaaatg acacagtgtt cgatgagcac aaggagtttc
    19921 atctttttca ctaggatttt agcccgggct aaaatcagct ctctgacttc agagggcttt
    19981 tttattgagg ttttatcggt aacaattttg gagactacaa aaacctcaaa tggtatcagc
    20041 taattacacc ataaaggtgc gcagttactc ggcttttcaa gccgagtagc tgtatgcaag
    20101 ccccctagaa gagcccactc tttacaaagt aaagtatagt atgttatact ttacatggaa
    20161 gtagtcactg aattccagtt agaaattact ttgtaactac gttttgagga ggagtaaaat
    20221 gctttcctac gttcgacatt acccactagc gatagctaaa ttaatgtgtc tgtgctctcc
    20281 taaaatctgc tgatttatta ctgactaata caggaggttt tttttatggg acagacaatc
    20341 atatctgcta ttggtgttta tatttccacc agtatcgatt atttaattat tttaattatt
    20401 ttatttgcac agctatcaca gaataaacag aaatggcata tttatgcggg gcaatatcta
    20461 ggcacaggct tacttgtagg ggcgagttta gttgctgctt atgtcgttaa tttcgtgcct
    20521 gaagaatgga tggttggatt gcttggttta atccctatct atttagggat tcgctttgca
    20581 attgttggag aagatgcgga agaagaagag gaagaaatta ttgaaagatt agaacaaagc
    20641 aaggcaaatc aactgttttg gacagttaca ttgctgacaa ttgcgtctgg cggagataat
    20701 ttaggtatct atatacctta ttttgcttcg ttagattggt cacagaccct cgtggccttg
    20761 cttgtgtttg taatcggcat aattatcttt tgcgagatta gtcgggtgtt atcctctatt
    20821 ccgttaatat tcgagacaat tgaaaaatac gagcgaatca ttgtgccctt agtattcatt
    20881 ctacttggac tatacatcat gtatgaaaat ggcacgatag agacttttct gatcgtgtag
    20941 atttttttgt ttcactagga ttttagcccg agctcaaatc agctctctga ttttcagggg
    21001 gctttttcat tgagtataaa tggacaatct taaagttact ctattgtaga gtggcttttg
    21061 atttgattag gagattctta taaatatagt aaaatgaaat aagaatagga caaatcgatc
    21121 aggacagtca aatcgatttc taaaaatgtt ttagaagtag aggtgtacta ttctagttcc
    21181 aatctactat ataaatgaaa accttagctg tttggccaag gttcatttct tctatgcaag
    21241 ttcttctctt ttcttatctg ggttccagat gaagcttgcg ataaagctaa agatgatggt
    21301 taggatagcg aggataatag caaggatgag ggcagggatg cggataaacc accagagtgg
    21361 atttggtttt ttatcattgt gccattgttt cgtttcttcg tccagacgtt ggaattctgt
    21421 ttgaatacga ttggcgactg tttcaatgcc ttcatcattc attttcttga tatctgagat
    21481 atcgattgga tttccaaagt tcatatcgac acgttcacgg ctaatcaagc ccttcaaagt
    21541 catgggaccg gtgtaggtaa ccggcatgat acggaccttg gccattttgg caatcagtgc
    21601 tgcgcccccc ttgacatcgt ttgagtggcg gctaccactt ggaaacatga tgagagagcg
    21661 gtcacttttt ttgagaacgt tgataggata tttgatggct gaggcgctgg gattttcacg
    21721 gtcgatggga aaggcgccac acatacgaat ccaccaacca aagatacggt tggtaaagag
    21781 ttcttttttt gccataaaga tgaactgttt tggcttggtc gcaaaggcca tataaacagg
    21841 atcccaccag gtacggtgag gcgcaactaa aatataattt tcatcttgat taggaatttt
    21901 atcagtatta tgatagtgag cattgccatt gatggaccat aagagcaata caactaatcc
    21961 acgcaaataa gtataaaaca tgcgatctcc ttcgattgtt ttcttgttat tattatacct
    22021 tatcaaagga gggctggcaa acttttccct tgactagata catatttagg atgaaattag
    22081 aattctgtta aaaaaaatga tataatagaa tttatggata aaaataagat tatgggatta
    22141 acccaaagag aagtcaagga aagacaggct gagggtttgg tcaatgactt taccgcatca
    22201 gccagtacca gcacttggca aatcgttaaa cgaaatgtct ttaccctttt taacgctttg
    22261 aactttgcca ttgctttggc tcttgccttt gtgcaggctt ggagcaatct ggtcttcttt
    22321 gctgttatct gctttaacgc tttttctggg attgtgaccg agctacgagc caaacacatg
    22381 gtggacaagc tcaatctcat gaccaaggaa aaggtcaaaa ccatccgtga tggtcaggaa
    22441 gttgctctta atcctgaaga attagtgcta ggagatgtca ttcgtttgtc tgcaggagag
    22501 cagattccta gtgatgcctt ggttttggaa ggctttgcgg aagtcaatga agccatgtta
    22561 acgggagaaa gtgatttggt gcaaaaggaa gttgacggct tacttttgtc aggaagtttc
    22621 ctagccagtg ggtcagtttt atctcaagtt caccatgtcg gtgcagacaa ctatgctgcc
    22681 aaactcatgc ttgaggctaa gaccgttaaa cccatcaact cccgtatcat gaaatcgctg
    22741 gacaagttgg ctggttttac tgggaagatt atcattccct ttggtctggc tctcttgctg
    22801 gaagccttgc ttttaaaagg cctgcctctc aagtcatccg ttgtaaactc gtcgacagct
    22861 cttttgggaa tgttgcctaa gggaattgcc cttttgacca ttacttcgct cttgactgca
    22921 gtgattaagt tgggcttgaa aaaggtcttg gtgcaggaga tgtactctgt tgagaccttg
    22981 gcgcgcgtgg atatgctctg tctggacaag acgggtacca tcacccaagg aaagatgcag
    23041 gtggaggctg ttcttccgtt gatggaaacg tatggtgaag aggctattgc cagcatcttg
    23101 actagctaca tggcccatag tgaggataag aatccaactg cccaagccat tcgccagcgt
    23161 tttgtgggag atgttgctta tcctatgatt tccaatcttc ccttctcgag cgaccgcaag
    23221 tggggggcta tggagttaga aggtttgggg acagttttct taggggcgcc tgagatgttg
    23281 ctggattctg aagtcccaga agccagggag gccttggaga gaggatcacg tgtcttggtc
    23341 ttagctctca gtcaggagaa attagaccat cacaaaccac agaaaccatc tgatattcag
    23401 gctctagcct tgctggaaat cttggactcc attcgagagg gagcagcaga gacgctggac
    23461 tatctccgtt ctcaggaggt aggactcaag attatctctg gtgacaatcc agttacggtg
    23521 tccagcattg cccagaaggc tggttttgcg gactatcaca actatgtaga ttgctcaaaa
    23581 atcaccgatg aggaattgat ggccatggcg gaggagacag ctattttcgg acgtgtttcc
    23641 cctcatcaaa agaaactcat catccaaacg ttgaaaaaag cgggtcatac aacggctatg
    23701 acaggggacg gggttaatga tatcttggcc cttcgtgagg cggattgttc tatcgtgatg
    23761 gcggaggggg atccagcaac ccgtcagatt gccaatctgg ttctcttgaa ctcagacttt
    23821 aatgatgttc ctgagattct cttcgagggt cgtcgcgtgg tcaataacat tgcccacatc
    23881 gccccgattt tcttgataaa gaccatctat tccttcctgt tagcagtcat ctgtattgcc
    23941 agtgctttac taggtcggtc agagtggatt ttgattttcc ccttcattcc gatccagatt
    24001 accatgattg accagtttgt ggaaggtttc ccaccattcg ttctgacttt tgagcgaaat
    24061 atcaaacctg ttgagcagaa tttcctcaga aaatccatgc ttcgtgccct accaagcgct
    24121 ctcatggtcg tctttagcgt cctgtttgtg aaaatatttg ggagtagcca aggttggtct
    24181 gagttagaaa tctcaactct cctctattat ctcttggggt caattggttt cttatccgta
    24241 tttagagcct gcatgccatt taccctatgg cgtgtcctct tgattgtttg gtcagtagga
    24301 ggtttcctag ccacagctct cttcccaaga atccaaaaac tgcttgaaat ttcaacctta
    24361 acaggacaaa cattacctgt ttatggtgtc atgatgttgg tctttaccgt gattttcatc
    24421 ctgaccagtc gctatcaagc cagaaaataa agaaaggctg caatctgtgg attgcagttt
    24481 ttttaggtac aagattgcca gtcgaaatgt ggtataataa gaggtaatag agttttggaa
    24541 agtgagagaa gatgatttca aagagattag aattggtagc ttcctttgtg tcacaggggg
    24601 ctattttact agatgtggga agtgaccatg cttatctgcc tatcgagttg gttgagagag
    24661 gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg tccctatcag tctgcggtta
    24721 aaaatgttga ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc aatggcttgg
    24781 cagcttttga agagactgac caagtgtctg tcattaccat tgctggcatg ggtggtcgtt
    24841 tgattgctag gattttagaa gaaggtttgg ggaagttagc taatgtagag cgtttgatcc
    24901 tccagcccaa taatcgtgaa gacgacttgc gtatctggct acaggatcat ggattccaga
    24961 ttgtagcaga aagcatttta gaagaagctg gaaagtttta tgagattttg gtggtggaag
    25021 caggacaaat gaagctatca gccagtgatg ttcgctttgg tcccttcttg tccaaagaag
    25081 tcagtccagt atttgtccaa aaatggcaaa aagaagctga gaagctagag ttcgccctcg
    25141 gacaaatccc agaaaaaaat ctggaagaac gtcaagttct agtagataag attcaagcta
    25201 tcaaggaggt gctccatgtt agcaagtgaa gtgatccaag cttatgaagc cttttgccct
    25261 caggaatttt ctatggaggg agacagccgt ggtctgcaaa ttggcacttt agacaagggt
    25321 atccaaaggg tcatggttgc cctcgatatt cgtgaagaga cggtggcaga ggctattgaa
    25381 aagggtgtgg acttgattat cgtcaagcac gcgcctatct ttcgtcctat caaggacttg
    25441 cttgccagcc gtccgcaaaa tcagatttac atcgacctga ttaagcatga tatcgcagtt
    25501 tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc tcaatgactg gttttgtcag
    25561 atgctaggaa tcgaggagac gacttatctg caggaaacag gtccagaacg tggaattgga
    25621 cgtattggga atattcagcc tcagacattt tgggaattgg cccaacaggt caagcaagtc
    25681 tttgacctag atagccttcg aatggtgcat tatcaagaga atgatttgca gaagcctatt
    25741 tcaagagtag caatttgtgg tggaagcggg cagtctttct ataaggatgc tttggcaaag
    25801 ggggcagatg tctatatcac tggtgatatc tactaccata ctgctcagga tatgctgtct
    25861 gatggcttgt tagcattgga tccaggtcac tatatcgaag tgctttttgt ggaaaaaatc
    25921 gcagcactcc ttactcaatg gaaagagaaa aaaggctggg aactagagat tttacctagt
    25981 caagcatcga ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa tgaaaaaagt
    26041 tgccattatt ggagcaggaa ttgtgggagc aacagctgcc tactacctct cgagagaaag
    26101 tgacctagag gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg ccgcagcagg
    26161 aattatcagt ccttggtttt ccaaacgccg taataaagcc tggtacaaga tggcgcgctt
    26221 gggggctgat ttttatgtgg atttattagc tgatttagag aaatcaggac aagaaatcga
    26281 cttttaccag cgttcgggag tctttctctt gaaaaaggat gaatccaagt tggaagaact
    26341 ctatcaactg gctctccagc gcagagaaga atctcccctg ataggccagt tagccattct
    26401 ggatcaagca tcagctaatg aattattccc tggcttgcag ggattcgaca acttgctcta
    26461 tgcttctggt ggagcgagag tagatggcca actcttggta actcgtctgc tagaagccag
    26521 tcatgtcaag ttggtcaaag aaaaagtgac tctgacactc ttatcatcag gctaccagat
    26581 tggcgaagag gtgtttgatc aggttatttt ggcaacggga gcttggttgg gggacatgtt
    26641 agaaccttta ggttatgaag tggatgtccg tcctcaaaaa ggacaactac gagattatca
    26701 gcttgcccaa gacatggaag attaccctgt tgtcatgcca gaaggggagt gggatttgat
    26761 tccctttgca ggtgggaaat tatccttggg cgctacccat gaaaatgaca tgggatttga
    26821 tttgacggta gatgaaccct tgctccaaca aatggaggag gcggccttgc ctcattaccc
    26881 agttttagct agagtgactt caagggctga gcgtgtggga atccgtgcct ataccagtga
    26941 tttctctccc ttctttgggc aggtgccaga attggcaggt gtctatgcag ccagtggact
    27001 aggttcatca ggcctcacaa ctggtcctat cattggttac catctagccc aactgatcca
    27061 agacaaggag ttgaccttgg accctctaaa ttacccaatt gaaaactatg tcaaacgagt
    27121 aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact aggtaactag ccgcgggtta
    27181 ctcaaagcac tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
    27241 tgaggttgtg gatagaactg acgaagtcag taaccatacc catggcaagg cgacgttgac
    27301 gtggtttgaa ttggattttc gaagagtata agcattttac tgaaatttta tcaggtagtt
    27361 taggatggca aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat aatctgagaa
    27421 tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt ggtgccggtt ttattggaac
    27481 ccacactgtt attgaattga tccaagcagg ccatcaagtt gttgtggtgg ataatcttgt
    27541 caatagcaat cgtaagagtt tagaagttgt tgaaagaatc acaggagttg agattccttt
    27601 ctatgaggca gatattcgtg acacagctac cctcagagat attttcaagc aggaagaacc
    27661 gactggtgtc attcactttg ctggtttgaa ggctgttggc gaatcaacac gtatccctct
    27721 tgcctactat gacaacaata tcgctggaac tgtcagcctt ttgaaagcca tggaagaaaa
    27781 caactgtaaa aacatcatct tcagttcttc tgcgacagtt tacggggatc cgcacacagt
    27841 gcccatcttg gaagatttcc cactttcagt gaccaaccca tacggtcgta ctaagctcat
    27901 gctagaggaa attttgactg atatttacaa agcagactca gaatggaatg ttgtcttgct
    27961 tcgttacttt aacccaatcg gagcccatga gagtggtgat ttgggagaaa atccaaacgg
    28021 tattccaaac aatctcttgc catatgtgac tcaagtagcc gttggaaaat tagagcaagt
    28081 gcaagtgttt ggagacgatt acgatacgga agatggaaca ggtgttcgtg actatatcca
    28141 cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa aaggttcagg
    28201 actaaacgtt tataaccttg gaactggtaa aggttactca gttcttgaaa ttatccaaaa
    28261 catggaaaaa gcggtgggcc gtcctattcc ttaccgcatc gtagaacgtc gcccaggtga
    28321 tatcgctgcc tgctactcag acccggcaaa agctaaagca gaactcggtt gggaagcaga
    28381 actcgacatc acccaaatgt gtgaagacgc atggcgttgg caaagcaagc atccaaatgg
    28441 atttgaagac taagatgatg atttcaatca tcgtcccttg tttaaacgaa gaggaagtac
    28501 ttcctctttt ttatcaggct ctggaagctt tacttccaga tttggaaaca gaaatcgagt
    28561 atgtctttgt cgatgatgga tcaagtgatg ggaccttgga actcttaaag gcctatcggg
    28621 agcaaaatcc ggcagtccat tatatttctt tctctcgaaa ttttggcaaa gaagcagccc
    28681 tttatgcagg cttgcaatat gcgacaggag atttggtggt ggtgatggat gcagacctcc
    28741 aagatcctcc tagtatgttg tttgagatga aaaatgtact agacaaaaat gtagacttgg
    28801 actgcgttgg gacacggaga actagtcggg agggagaacc cttctttcgc agtttctgtg
    28861 ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg tcgggtgtcc
    28921 gtgattttcg tatgatgaga aggtctgtag tcgatgccat tttaagcttg accgagtcca
    28981 atcgtttttc aaaggggctc ttcgcctggg tgggtttcaa aacctactat ttggactatc
    29041 caaatgtcga aaggcaggct ggcaagacca gttggagttt taggcaactc tttttttact
    29101 ccattgaagg gattgttaat ttttcagatt tccctttgac tatagccttt gtagctggtc
    29161 tcctatcttg ttttctttct ctgctgatga ccttttttgt tgtggttcgg accctcattt
    29221 tgggcaatcc gacatctggt tggacctctc tgatggctgt tattctcttt cttggaggca
    29281 ttcaactctt gaccattggg attctcggta agtatatcag taagatttat ttagagacta
    29341 aaaaaagacc actttatctt atcaaagaaa aaagtgacct tcctgatttt acagaaaaaa
    29401 taaagtgaaa agactataat tttacatgga aatgtgctaa actagaggga gtggattatc
    29461 gccattgatt taggcttcct ggtttccaat cagggcgcga gttgggcaat ttttaacagc
    29521 ctctaagaca tcctgactag gagaaatttc tttttccagt tggtcagggt catcgtaaaa
    29581 acgcacgatt ccattatcgt ggtaatcaaa taaatcagaa taagtttggc aaagtccaca
    29641 ggcgatacat cgttcaggta taagtgtgat tttcatgttc atatttatat tgtaataaga
    29701 aaagtaaaaa aaaaacaagg agtaaggtat ggcaaaagaa ccgtggcaag aagatattta
    29761 tgatcaagaa gaatcaagag cagggcgtcg gcatcgaaac cacggagggg ctgataggat
    29821 ggctaatcgt attttgacga tcctagctag tattttcttt gtaattgtgg tggtgatggt
    29881 catcgttctc atctatctat catcgggggg gagtaatcgc acagcagcct taaaagactt
    29941 tcatgattct gatgcaagtg tagtacaaat ctcatcttca agcagttctc agcctgagca
    30001 gagttcagag ccagaatcta cttctagtag ttcagaagaa gctgctaatc ctgaaggaac
    30061 gattaaagtt ctcgcaggag aaggggaagc agctattgcc gctcgtgcag gaatctccat
    30121 tgctcagtta gaggccttga atcctgggca catggctaca ggatcttggt ttgctaatcc
    30181 aggtgatgtt ataaaaataa aataggagcc gatatgaaaa caattcaaat tgctattgat
    30241 ggtcctgctt ccagcggtaa gagtacggtc gcaaagatta ttgctaagga ttttgggttc
    30301 acctaccttg atacaggagc tatgtatcgt gcagcgacct atatggctct taagaaccaa
    30361 ttaggagttg aagaagtcga agaccttcta gccttgttgg accagcatcc aatcagcttt
    30421 ggacgttcag aaactggaga ccagcttgtt tttgtaggag atgtggatat tacccatcct
    30481 atccgtgaaa atgaagtgac caatcatgtt tctgctattg cagcaattcc tgaagtgcgt
    30541 gagaaactgg tttctctcca acaagaaatt gcccagcaag gcgggattgt catggatggt
    30601 cgcgatattg gaactgttgt attgccacaa gcagaattga aaattttcct agtagcttct
    30661 gttgatgaga gagcagagcg tcgttacaag gaaaatattg ccaagggaat tgaaacagac
    30721 cttgaaaccc taaaaaagga aattgctgcg cgtgactaca aggatagtca tcgtgagact
    30781 tctcctctca aacaagcaga ggatgctgtc taccttgata caactggttt gaacattcaa
    30841 gaagtagttg aaaaaatcaa agcagaagct gaaaaaagaa tgtaaatgta gaaaagccga
    30901 tagattgata tcggtttttt tctaaatttg tcaaaatgct gattttaggg tataatagtt
    30961 gctgttcgag aaattttgat tttcaaagaa tagtgaatga tgataaggag aaaccatgaa
    31021 caatttacca aattgtccaa aatgtaactc agagtatgtc tacgaagacg gtgccctact
    31081 ggtttgccca gagtgtgctc atgagtggaa tcctgctgaa gttgcagaag tagaagaagg
    31141 tcttgtcgct atcgatgcca acggaaataa attgactgat ggtgatacag taactctcat
    31201 caaggacttg aaagtaaaag gtgcgccaaa agatttgaaa caagggacgc gcgtgaaaaa
    31261 tatccgcatc gtagaaggcg atcacaatat cgactgtaag attgatggtt ttggtgccat
    31321 gaaacttaaa tcagagtttg tgaggaagat ttaagcatgt caaaacacta taaacttgta
    31381 ttttatagcc gtatcttctt gtttctagcg gcttttacgg gagtttatct tgaaattact
    31441 aggcatggtg gttttgggat gcttctctat tacacggttc tgtccaacct cttggtaact
    31501 atttttaccc tttatcttct aaaggttatg agccgtgtag gtgaaaattg gcaaaggcca
    31561 agtctcttgc gcttaaaagg tggggtcacc atgagtatca tgattacctg tgtgatttac
    31621 catttcctct tggcgcccat tgcgactaat ttctataccc tagaaaattt cctttgccac
    31681 tatatcgttc ccatctggtt tttagcggat accctctttt ttgacaaaca gggtcaatac
    31741 aagatttggg atccagcagt gtggaccatt ttaccctttc tgtatatgat gtttgctctt
    31801 tttaatggct tggttctaaa actcaatatt ccaaatgcca aggataatcc tttcccttac
    31861 ttctttttga atgtgaacaa gggttggaat gttgtgttta agtggtgtct gattatcttt
    31921 gttgcctata tggtagcagg atttattttc tactttatca agcaaatcaa gagaaagtca
    31981 tcctaatact cttcgaaaat ctcttcaaac cacgttagtt tccatctgca acctcaaaac
    32041 actgttttga acaacctgcg gctagctttc tagtttgctc tttgattttc attgagtatg
    32101 agatacaagg gattcatttt cgaatttaag aaggagtcta caaaccaatg aggcttcttc
    32161 ttttcttgct tatttgataa ctatcaaaaa agtagaagat taagagaaat atagaaagag
    32221 atttcatgaa acaattttta gaacgggcca gcattttggc tctctccctc gttttgatta
    32281 cctccttttc catttcgagt gccctaccag ccatgtttga ctattatcag ggttattcta
    32341 aggaacaaat tgagctcttg gtgagcttgc cttcctttgg aatcatgatg atgttactgc
    32401 taaatggttt cttagaaaaa atatttcctg agcgcttaca gattagtttg ggcttgctga
    32461 ttttatcatt gagcggtaca gctcccttct ggtaccaagc ctatcccttt gtctttggaa
    32521 cacggcttct ctttggtttg ggtcttggga tgatcaatgc caaggccatt tctattatca
    32581 gtgaacgcta ccaaggaaaa aggcgaattc agatgttagg gctacgcgct tctgcagagg
    32641 tcgttggagc ttctctcatt accttggccg tcggtcagtt gttggccttt ggttggacag
    32701 ctatctttct agcctatagt gctggatttt tggtgatgcc cctttatctg ctctttgtcc
    32761 cttatggaaa atcaaagaaa gaagtcaaga aaagagcgaa ggaagcaagt cgtttaactc
    32821 gagaaatgaa aggcttgatt tttaccttag ctatcgaagc ggcagttgta gtttgtacca
    32881 atacagctat taccatccgt attccaagtt tgatggtgga aagaggattg ggggatgccc
    32941 agttatctag ttttgttctt agtatcatgc agttgatcgg gattgtggct ggggtgagtt
    33001 tttctttctt gatttctatc tttaaagaga aactgctcct ctggtctggt attacctttg
    33061 gcttggggca aatcgtgatt gccttgtctt catccttgtg ggtggtagta gcaggaagtg
    33121 ttctggctgg atttgcctat agtgtagtct tgacgacggt ctttcaactt gtctctgaac
    33181 gaattccagc taaactcctc aatcaagcaa cttcatttgc tgtattaggc tgtagtttcg
    33241 gagcctttac gaccccattt gttctaggtg caattggctt actaactcac aatgggatgt
    33301 tggtctttag tatcttagga ggttggttga ttgtaatctc tatctttgtc atgtacctac
    33361 ttcagaagag agcttaggat tgattcctaa gtttttcttt tgatactcaa tgaaaatcaa
    33421 agagcatagt tgattgagtt tggaatagta cgctgtagct gctaaaatat ttctagaaat
    33481 taatttgact tttctaatag agttattcat atcttatttc aatctactat agaaagctag
    33541 ccgcaggttg ctcaaaatag tgttttgagg ttgcagatgg aaactgacgt ggtttgaaga
    33601 gattttcgaa gagtatgaga tttttatacc catacaatat ttgttttagg tccttgttta
    33661 cagactaatt tcttgataaa atagaggtta tgacgagata taaagcaact atttcctatg
    33721 atggttatgc ctttgctggc tttcagcgcc agtctcatgc gcgtagcgtt caggaagaaa
    33781 ttgaaaaaac cttgaccaga ttaaataaag ggcaaaccat tactgttcac ggtgctggta
    33841 ggacagatag tggggttcat gccctgggac aggtcattca ttttgacctg ccttatcaga
    33901 tggatgagga gaaactccgt tttgccttgg atacccagtc tcctgaagat attgatgtga
    33961 tttcgattga gcttgtggca gatgattttc attgccgtta tgccaaacat agcaagacct
    34021 atgagtttat tgtggataga ggacgtccca aaaatcctat gcgccgtcac tatgccaccc
    34081 actttcccta cccactcgat gtggaacgaa tgcagattgc aatcaaaaag ctagagggaa
    34141 cccatgattt taccggtttt acagcctctg ggactagtgt agaggataag gttcgcacca
    34201 tcacagaagc tagtttaata gtcgatgaga caggacaatt tttgaccttt accttttcag
    34261 gaaatggttt cttgtataaa cagattcgca atatggtggg gactcttctc aaaatcggta
    34321 acaaccgcat gccagtagag cagattgatc tcatcttgga gaagaaggac aggcaacttg
    34381 caggtcccac tgcagcacca aatggtttgt atttaaagga gattcgttat gaagaataat
    34441 cgtattttag cactttctgg aaatgatatt tttagtggtg gtggactgtc agctgatttg
    34501 gctacctata ccttgaacgg cttgcatggg tttgtagcag tgacttgttt gacagccttg
    34561 acagaaaaag gatttgaagt ctttccaact gatgatacca tttttcaaca tgaattagat
    34621 agcttacgtg atgtggaatt tgggggaatt aagattggtc ttctccctac tgtcagtgtg
    34681 gctgagaagg ccttggactt tatcaaacaa cgcccaggag tacctgtggt gttggatcct
    34741 gtcttggtct gcaaggaaac gcatgatgta gctgtcagtg agctctgcca agagttgatt
    34801 cgctttttcc cttatgtcag tgtgattacg cctaatctcc cagaagcaga attattatcc
    34861 ggtcaggaaa ttaaaacctt ggaagacatg aaaactgcag cgcagaaatt gcatgattta
    34921 ggagcgccag cagtcattat caagggaggc aatcgtctta gtcaggacaa ggctgtggat
    34981 gtcttttatg atggacagac ctttactatc ctagaaaatc cagttatcca aggccaaaat
    35041 gctggtgcag gttgtacctt tgcctctagc attgccagtc acttgattaa aggtgataaa
    35101 cttttgccag cagtagaaag ctctaaggct ttcgtttatc gtgctattgc acaagcagat
    35161 cagtatggag taagacaata tgaagcaaac aaaaacaact aaaatcgccc ttgtatccct
    35221 attaaccgcc ctttctgtgg ttctaggtta tttcttaaaa atcccaacac ctacaggaat
    35281 tctaactctt ttagatgctg gtgtcttctt tgcggccttt tactttggta gtcgtgaagg
    35341 agcggtagtc ggaggactag caagtttctt gattgacctc ttatcaggct accctcagtg
    35401 gatgttcttt agcttggtca accatggctt gcagggattt ttcgcaggat ttaaaggaaa
    35461 aagtcagtgg ttaggcctta ttttagcaac tattgccatg gtaggaggct acgccttggg
    35521 ttctactttg atgaatggct gggcagcagc cctcccagaa attctaccaa atttcatgca
    35581 aaatatggta gggatgattg taggatttat tcttagtcaa agtatcaaga agattaagta
    35641 atactcttcg aaaatctctt caaaccacgt cagcttccat ctgcaacctc aaaacactgt
    35701 tttgagcagc ctgaggctag ctttctagtt tgcactttga ttttcattga gtataaagag
    35761 gttgagtaaa aagtatttca aataagaaaa acgcatagta tcaggtgttg aatgaactgc
    35821 cccccaaaag ttagacagaa aaaatctaac ttttggggtg ttttattatg aaactaactt
    35881 atgatgataa agttcagatc tatgaactta gaaaacaagg atatagctta gagaagcttt
    35941 caaataaatt tgggataaac aattctaatc ttaggtacat gattaaattg attgatcgtt
    36001 acggaataga gttcgtcaaa aaagggaaaa atcgttacta ttctcctgat ttaaaacaag
    36061 aaatgattca taaagtctga catgaaggct agactaaaga tagagtttct cttgaatacg
    36121 gtctcccaag tcgtacgata cttcttaact ggctagcaca atacaggaaa aacgggtata
    36181 ctattgttga gaaaacaaga gggagagtac ctaaaatggg acgtaagcca aaaaagagac
    36241 ctgaagagag gacagaatta gaacgtcttc aagcagaaaa tgagtacctg agagcggaga
    36301 atgccatcct aaaaaagtta agagaactcc gattgaagga ggaaaaagag aaagacagaa
    36361 attgtttaag aattaatgac tgagttttcg ttagatcttc ttctaaaagc cattaaacta
    36421 gctcgttcga cctactacta tcacttgaaa cagctagaca aaacagataa ggaccaagag
    36481 cttaaagctg aaattcaatc catttttatc gaacacaagg gaaattatgc ttatcgtcga
    36541 attcatttag aactaagaaa tcgtggttat ctggtaaatc ataaaagagt tcaaggcttg
    36601 atgaaagtac tcaatttaca agctaaaatg cgacagaaac gaaaatattc ttctcataaa
    36661 ggagacgttg gtaagaaagc agagaatctc attcaaggcc aatttgaagg ctctaaaaca
    36721 atggaacagt gctacacaga tgtgactgaa tttgccattc cagcaagtac tcaaaagctt
    36781 tacttatcac cagttttaga tggctttaat agcgaaatta tcgcctataa tctttcaact
    36841 tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga gaagcactac
    36901 gagaatacga ttctccatag tgaccaaggc tggcaatatc aacacgattc ttatcatcag
    36961 tttcttgagg gtaagggaat tcaagcatcc atgtcacgca agggaaacag ccaagacaac
    37021 ggtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag
    37081 tcgtttcagt cgcttaagca attggaacaa gctattgtag actatattga ttactacaac
    37141 aataaacgaa ttaaggtaaa actaaaagga cttagtcctg tgcaatacag aactaaatcc
    37201 ttcggataaa ttaattgtct aactgtttgg gggcagtaca ttttaacact tgatactatg
    37261 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
    37321 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
    37381 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
    37441 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
    37501 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
    37561 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
    37621 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
    37681 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
    37741 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
    37801 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
    37861 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
    37921 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
    37981 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
    38041 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
    38101 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
    38161 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
    38221 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
    38281 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
    38341 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
    38401 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
    38461 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
    38521 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
    38581 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
    38641 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
    38701 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
    38761 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
    38821 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
    38881 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
    38941 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
    39001 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
    39061 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
    39121 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
    39181 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
    39241 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
    39301 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
    39361 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
    39421 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
    39481 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
    39541 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
    39601 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
    39661 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
    39721 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
    39781 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
    39841 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
    39901 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
    39961 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
    40021 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
    40081 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
    40141 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
    40201 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
    40261 cccttcggta ttgtagtgag caagttgggc tggtcctttt tccaagtcaa aaccaaaata
    40321 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
    40381 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
    40441 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
    40501 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
    40561 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
    40621 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
    40681 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
    40741 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
    40801 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
    40861 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
    40921 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
    40981 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
    41041 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
    41101 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
    41161 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
    41221 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
    41281 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
    41341 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
    41401 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
    41461 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
    41521 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
    41581 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
    41641 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
    41701 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
    41761 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
    41821 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
    41881 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
    41941 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
    42001 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
    42061 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
    42121 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
    42181 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
    42241 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
    42301 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
    42361 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
    42421 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
    42481 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
    42541 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
    42601 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
    42661 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
    42721 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
    42781 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
    42841 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
    42901 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
    42961 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
    43021 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
    43081 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
    43141 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
    43201 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
    43261 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
    43321 gtcgccctct aacctttagt atattactgc ttgtcaatct tttcttttct ctctcacttt
    43381 ggctctttac agattccgtt ttatttgtag ttgctatgtc tattttgatg acttgctatg
    43441 gagctggttt ttctttgatt ccagcttatc tcagtgatat ttttggaacc aaggaattgg
    43501 ccgctctgca tggttatatt ttaacagctt gggcaatggc tggtttagcg ggacctattt
    43561 tattagcaga gacttataaa atggctcatt cgtacacaca aaccttgttc gtttttctca
    43621 ttttatacag tatcgccttg gctttgtctt attatctagg tcgttcaatc aaaaaagaaa
    43681 gtcaaaaacc gcttacatga ttttctgtag aaatggggct atcttttgct ctggtcttgt
    43741 gttatactag ataggttgca aagaaaacag tacttttctt ttgtggaaaa gaagcaacac
    43801 gattttatat ctagttatat gaaaatacgt cataaaaaga aaagtataaa ctaagcccta
    43861 tagggtggct tcgcaccacc tttagaaaga agaataacgt gaaatttaat gaattaaact
    43921 tgtctgctga tttgctagca gaaattgaaa aagctggttt tgtagaagct agtcctatcc
    43981 aagaacaaac tattcctttg gcccttgaag gcaaggatgt tatcggtcaa gctcagactg
    44041 gtacaggaaa aactgcagcc tttggcttgc ctacccttga aaaaatccgt atagaagaag
    44101 cgactattca agccttggtc atcgctccaa ctcgtgaact agctgtccaa agtcaagaag
    44161 aactcttccg ctttggtcgt agtaagggag tcaaagtccg ttcagtatat ggcggatcaa
    44221 gcattgaaaa acaaattaag gctcttaaat ctggtgccca tatcgtggtg ggaactccag
    44281 gtcgcctctt ggacttgatt aaacgcaagg ccttgaaatt acaagacatt gaaaccctta
    44341 tccttgacga agcggatgaa atgcttaaca tgggcttcct tgaagacatc gaagccatta
    44401 tttcccgtgt acctgagaac cgtcaaactt tgcttttctc agcaactatg ccagatgcca
    44461 tcaaacgtat cggtgttcag tttatgaaag cccctgaaca tgtcaagatt gcggctaagg
    44521 aattgacaac agaattggtt gaccagtact atatccgtgt taaggaacaa gaaaaatttg
    44581 acaccatgac tcgtctcatg gatgtggcac aaccagaact cgctattgta tttggtcgta
    44641 ccaaacgccg tgtggatgaa ttgactcgtg gtttgaaaat tcgtggcttc cgtgcagaag
    44701 gaattcatgg cgacctagac caaaacaaac gtcttcgtgt ccttcgtgac tttaaaaatg
    44761 gcaatcttga tgttttggtt gcgacagacg ttgcagcgcg tggtttggat atttcaggtg
    44821 tgacccatgt ctacaactac gatattccac aagatcctga gagttatgtt caccgtatcg
    44881 gtcgtacagg tcgtgctggt aagtcaggtc aatctattac ttttgttgct ccaaacgaaa
    44941 tgggttacct tcaaatcatt gaaaacttga ctaagaaacg catgaaaggt ctcaaacctg
    45001 caagtgtaga agaatccttc caatcaaaaa aacaggtagc tctcaagaaa atcgaacgtg
    45061 attttgcaga tgaaaccatt cgtgccaact ttgagaaatt tggtaaggat gctcgcaaat
    45121 tggctgctga gtttactcca gaagaattgg caatgtatat cttgagtctg acagtccaag
    45181 acccagatag ccttccagaa gtggagattg cacgtgaaaa accactaccg tttaaaccat
    45241 caggtaatgg tttcggtggt aaagctaagg gaggtcgtgg aggccgtcgt ggggacgacc
    45301 gtcgagagcg tgatcgtcgt ggcaatggtc gccgtgatga gttcaaaaaa ggaagtcgtg
    45361 gcaacgatcg ttttgataag gaaaaacgtt accgtaagga taataaaaaa ccacgcaata
    45421 ctttaagcga aaagcaaaca ggctttgtta ttcgtaacaa aggtgataaa taagaaaaag
    45481 cggttcaaaa tgaatcgctt ttttatataa ggagaccgaa tgtgaaaaag acaaataaaa
    45541 ttattatatt atcttttata atattatgat acacaaaaat aggcgacttg tcaatagaaa
    45601 aggaacaatt taattaaaaa tattctggtt tttaattaaa ttgtaagtca atgcaagtca
    45661 ataaggaatt ttcagataat tattgaaaaa gagacgtttt tatgttataa tgatagcgat
    45721 taaattcgag gtgaaaaatg gcacatttat tagaaaaaac tagaaaaatt acatcaattt
    45781 tgaaacgctc agaggagcag ttgcaggatg agctccctta caacgctatt acgcgtcagt
    45841 tagcggatat tattcattgc aatgcctgca ttatcaatag taagggacgt ctgcttggct
    45901 attttatgcg ttataaaaca aatacagatc gcgtagagca attcttccaa actaagattt
    45961 tcccagatga ctacgttcaa ggggctaata tgatttacga aacagaagca aacttgcctg
    46021 ttgagcatga tatgagtatt ttccctgttg agagtagaga tgattttcca gatggcttga
    46081 cgactattgc accgattcat gtatcgggga ttcgccttgg ttctttgatt atttggcgta
    46141 atgataaaaa attcgaagat gaggacttgg ttcttgttga gattgccagt accgttgttg
    46201 ggattcagct tcttaacttc caacgtgaag aagatgagaa aaatattcgt cgtcgtactg
    46261 ctgtcaccat ggcggtcaat accctttctt actccgaact ccgtgctgtt tcagcaattt
    46321 taggggaatt aaatggaaat gaagggaagt tgactgcgtc agtgattgca gatcgtatcg
    46381 gaatcactcg ctctgtgatt gtcaatgctc ttcgtaaact tgagtctgcg gggattattg
    46441 aaagtcgctc acttggaatg aagggaacct atcttaaggt cttgatttca gatatttttg
    46501 aagaagtgaa gaaaagagat tactaatgac aaaggcttta atttcgattg attatacaga
    46561 agattttgtt gctgatagtg ggaagctgac agcaggtgct ccagctcagg cgatttcgga
    46621 tgccatcagc aaggtaactc gattagcttt tgaacgagga gattatatct tctttactat
    46681 tgatgctcat gaagaaaacg attgtttcca tccggaaagt aagttatttc ctcctcataa
    46741 tctgattggg acgagtggac ggaatttata tggagatttg gggatctttt atcaagagca
    46801 tggttcagac agtcgtgtct tttggatgga taaacgccat tactcagctt tttcagggac
    46861 tgacctagat attcgtttga gagagcgtag agtgtctacc gttatcttaa caggtgtctt
    46921 gacggatatc tgtgtcctac atacagctat agatgcctat aatctaggat atgacatcga
    46981 gattgttaaa ccagctgttg cttccatctg gcctgaaaat catcaatttg ccctaggtca
    47041 tttcaaaaat acactcggag ctaagttagt agatgaaaat ctaaatgaac tttctgagta
    47101 acctggttgg tgaaaatgaa aaaatttgaa aaaaagtgtt gacaagcatc ccaaaagttg
    47161 atatactagt aaagtaatcg atgcggggat ggcggaattg gcagacgcgc aggactaagg
    47221 atcctgtgac cgctttaggt cgtgagggtt caagtccctc tctccgcata ggaaaagagt
    47281 tagctaaagc tagctctttt gtatttctct aaaaaattag aatccagtca aatgtagtgg
    47341 agaatcagcg aaaatatggg aaaactgatc cttgtttctg cttttgtcat agaagaataa
    47401 taaagattat cttcttcaaa ttctccgata ttctctaaag ttttgtgcaa gttgcacaga
    47461 acttttttat ttttttggtc atcttgccat agaaatataa agcgttttca tctataatat
    47521 aattatcaaa agacaaaagg agttcacctc atggtagaat tgaatcttaa aaatatttac
    47581 aaaaaatatc caaacagcga acactattca gttgaagatt tcaacttgaa catcaaagat
    47641 aaagaattta tcgttttcgt aggaccttca ggatgtggta aatcaactac actccgtatg
    47701 attgctggtc ttgaagacat cacagaaggt actgcatcta tcgatggcgt ggttgtcaac
    47761 gacgtagctc caaaagaccg tgatatcgcc atggtattcc aaaactacgc tctttaccca
    47821 cacatgactg tttatgacaa catggctttc ggtttgaaat tgcgtaaata cagcaaagaa
    47881 gacattaaca aacgtgttca agaagcagct gaaatacttg gattgaaaga attcttggaa
    47941 cgtaaaccgg ctgacctttc aggtggtcaa cgtcaacgtg ttgccatggg gcgtgcgatt
    48001 gtccgtgatg cgaaagtatt cttgatggac gaacctttgt caaacttgga tgccaaactt
    48061 cgtgtatcaa tgcgtgctga aatcgctaaa attcaccgtc gtatcggagc tacaactatc
    48121 tatgtaactc acgaccaaac agaagcgatg acacttgcag accgtatcgt tattatgtca
    48181 gctactaaga accctgctgg tacaggtact atcggacgtg tagaacaaat cggtactcct
    48241 caagaagttt acaaaaatcc agttaacaaa ttcgttgcag gattcatcgg aagcccagct
    48301 atgaacttca tcaacgtgaa attggttggt agcgaaattg tttctgacgg tttccgtttg
    48361 aaagtgccag aaggagcatt gaaagttctt cgtgaaaaag gctacgaagg aaaagaattg
    48421 atctttggta tccgtccaga agacgtgaat gcagaacctg ctttccttga aacattccca
    48481 gactgtgttg taaaagcgac tatctctgta tcagaactgc ttggttcaga atctcacctt
    48541 tactgccaag ttggtaaaga cgagtttgtt gcaaaagttg atgctcgtga ctacttgcaa
    48601 acaggtgcaa cagttgagct tggatttgac ttgaacaaag cacacttctt cgatgtagaa
    48661 actgaaaaaa caatctacta agaataaata aaattcaaag cactacaaga aaagatatct
    48721 ctttatcaat tgtagtggag agatatcagt taatctaggg agagaaacaa aatgcttctc
    48781 tcctttttgc tagggaagtc atattataca tctatattgt gatgctcttt atactcttcg
    48841 aaaatctctt caaaccacgt caacgtcgcc ttgccgtacg tatgattact gacttcgtca
    48901 gttttatctg caacctcaaa gctgtacttt gagtagctta cggctagttt cctagtttgc
    48961 tctttgattt ccattgagta ttatttgtgg gtaccatcta caagtgaagc tatatgcgta
    49021 aactacgtga gcaattgaat tcgaactaga gaggtaataa taaatttatg ctatagttat
    49081 ggtgacttgt atgcttttga ttctagttta tcaaataata gattagaatt gtcagataat
    49141 atcattttgt gttataatga agaaaaaaca gaggtgttca aatgtcagaa gcaggtcata
    49201 agtttttagc aaaattgggg aaaaaacgct tacgtccagg tggaaagcgt gccacagatt
    49261 ggttaattgc agaaggagga ttttcaaaag aaaagagaat actagaggtt gcgtgtaata
    49321 ggggaactac agcaattgag ttggcacagc gttttggttg caagataact gctgttgata
    49381 tggatgctca agctttagaa gtggctaaaa aatctgctgg aacggcaggt gttgctcatt
    49441 taatcagttt tgaaagagca aatgcaatga aacttcctta tcaagatgct agttttgata
    49501 ttgttataaa tgaagctatg ctgactatgc aagccgatca agctaagaaa aaatgtgtaa
    49561 tggaatatct aagggtatta aaacctggag gtcttctctt gacacatgat gtgcttctta
    49621 aggaagctaa agagtctatc agacaggaat tatcacaagc aattcatgta aatgtaggtc
    49681 ctttaactca agatggttgg gaacaggtga tgatagaatc aggttattgt gatgtgaaag
    49741 cattgactgg tgaaatgaca ttaatgaaat tatcgggtat gatttatgac gaaggtttgc
    49801 taggaacttt gaaaatttgt gtaaatgctt gtaaaaagga gaatagaaag cagtttttaa
    49861 ctatgtataa aatgtttgct aagaataaac agaaattggg ctttattgcg atggctagtt
    49921 ataaatcgtc aaaacgttag ataattattg aagttaactt ttcctttttt ctttcttaaa
    49981 aaatatgcta taatagagag taaaaaactt tgaaagaaag aaaaaagatg aatttaaaag
    50041 attacattgc aacaattgaa aattatccaa aggaaggcat taccttccgt gatattagtc
    50101 ctttgatggc tgatggaaat gcttatagct acgctgttcg tgaaatcgtt cagtatgcta
    50161 ctgacaagaa agtcgacatg atcgtgggac ctgaagctcg tggatttatc gtgggttgtc
    50221 cagttgcctt tgagttggga attggttttg cgcctgttcg taagccaggt aaattgccac
    50281 gcgaagttat ttctgctgac tatgaaaaag agtacggtgt cgataccttg actatgcacg
    50341 cggatgccat taagccaggt caacgtgttc ttattgtaga tgaccttttg gcgacaggtg
    50401 gaactgttaa ggcaactatc gagatgattg aaaaacttgg tggtgttatg gcaggttgtg
    50461 ccttccttgt tgaattggat gaattgaacg gccgtgaaaa aatcggtgac tacgactaca
    50521 aagttcttat gcattattaa tgaaaacagt ccctagggct gttttctcta cactaggata
    50581 taaaaataga ctataactag ttagagaaaa actataattg aaaactatat cttcttgcag
    50641 tataataaaa ggactaagtg tttgagattt gtcttcaaac acatgcaatt attcctgaga
    50701 gagtacagtt aggagagggt tatgccgatt cgaattgata aaaaattgcc agctgttgag
    50761 attttacgga cagagaatat ctttgtcatg gatgatcaac gtgctgccca ccaagatatc
    50821 cgtcctttga agattttaat tttaaatctc atgccacaga aaatggtcac agagacccag
    50881 ttgttgcgcc acttggctaa tacaccccta caactggata ttgattttct ctatatggag
    50941 agccaccgtt ctaaaacaac tcgttcagag cacatggaga ccttctataa aacttttcct
    51001 gaagtcaagg atgagtattt tgatgggatg atcatcacgg gtgctccagt tgagcattta
    51061 ccatttgagg aagtggacta ttgggaggaa tttagacaga tgcttgagtg gtctaagact
    51121 catgtctatt cgacccttca tatctgttgg ggagctcagg ctgggcttta tctgcgctat
    51181 ggtgtagaaa aataccagat ggacagtaag ctatcaggta tttatcctca ggacacccta
    51241 aaagagggtc accttctatt tagaggcttt gatgatagct atgtatcccc tcattcacgg
    51301 cacacggaga tttctaagga agaggtctta aacaagacta atctcgagat tttatcagaa
    51361 ggacctcagg ttggggtttc tattttggcc agtcgtgatt tacgagaaat ttatagtttt
    51421 ggtcatttgg agtatgaccg tgataccttg gcaaaagagt attttcgaga tcgtgatgca
    51481 ggtttcgacc cacatattcc agaaaattac tttaaagatg atgatgttaa tcaggtacct
    51541 tgtctttgtt ggtcttcatc tgcagccctc tttttcagta attgggtaaa ccatgcggtc
    51601 tatcaggaga cgccttttga ctggagaaag atagaagatg atgcatctgc atatgggtat
    51661 ttataagagg aattatgaca tatttagacg cttttaaatc aggtaccttg gttttaccga
    51721 gtgccctgct cttgcatttt aaggaactct ttccttctag cgacgatttt ctggtttggc
    51781 aatttttcta tttgcaaaat acgacaggct tagaagaaat gtcgccaagc cagattgctg
    51841 aaaggattgg caaggaaatt tcggatgtca accagtccat ttctaatctg acggaaaggg
    51901 gactgctcca gtatcgtact atcgaattaa atggcgaaat tgaattgctc tttgatgcta
    51961 gtttggcctt ggaacgtttg gatgacctgt ttggagcagt tcattcaagt tcagaccagc
    52021 taacaccaca aaaccagctc aaggatttgg tggaaacctt ccagcaggag ttgggacgat
    52081 tgttgacgcc ttttgagatt gaggatttga ccaagacact aaaggaagat ggaaccagtg
    52141 ctgacttgat taaggaggct cttcgtgaag ctgttttgaa tggaaaacca aactggaagt
    52201 acattcaggc gattttgaga aactggcgcc atgaaggaat caagagtgtg gctcaaattg
    52261 aggccaagag agcagaaaga gaagcaagca atcctcagtt gacacaggta tctgcagatt
    52321 tcagaaatgc catggatctc tggaaggatt aatccatgca agtaggcttg aaatccgagt
    52381 aagatttgca agctgtgtat aattgtgata gaataaatag aaaataaatt gaaaaaagag
    52441 gtatgtgaaa tgtcacgtaa accatttatc gctggtaact ggaaaatgaa caaaaatcca
    52501 gaagaagcta aagcattcgt tgaagcagtt gcatcaaaac ttccttcatc agatcttgtt
    52561 gaagcaggta tcgctgctcc agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc
    52621 tcaaacctta aagttgctgc tcaaaactgc tactttgaaa atgcaggtgc tttcactggt
    52681 gaaactagcc cacaagtttt gaaagaaatc ggtactgact acgttgttat cggtcactca
    52741 gaacgccgtg actacttcca tgaaactgac gaagatatca acaaaaaagc aaaagcaatc
    52801 tttgcgaacg gtatgcttcc aatcatctgt tgtggtgaat cacttgaaac ttacgaagct
    52861 ggtaaagctg ctgaattcgt aggtgctcaa gtatctgctg cattggctgg attgactgct
    52921 gaacaagttg ctgcctcagt tatcgcttat gagccaatct gggctatcgg tactggtaaa
    52981 tcagcttcac aagacgatgc acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct
    53041 gactttggtc aagaagtcgc agacaaagtt cgtgttcaat acggtggttc tgttaaacct
    53101 gaaaatgttg cttcatacat ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg
    53161 tcacttgaag ctgaaagctt cttagctttg cttgactttg taaaataatc agtaagtagc
    53221 aaaagctagg tggaacagca ttcagatgtc tgttacattt tttataggag agcaaagatt
    53281 gaaaacaaaa attggattag caagtatctg tttactaggc ttggcaacta gtcatgtcgc
    53341 tgcaaatgaa actgaagtag caaaaacttc gcaggataca acgacagctt caagtagttc
    53401 agagcaaaat cagtcttcta ataaaacgca aacgagcgca gaagtacaga ctaatgctgc
    53461 tgcccactgg gatggggatt attatgtaaa ggatgatggt tctaaagctc aaagtgaatg
    53521 gatttttgac aactactata aggcttggtt ttatattaat tcagatggtc gttactcgca
    53581 gaatgaatgg catggaaatt actacctgaa atcaggtgga tatatggccc aaaacgagtg
    53641 gatctatgac agtaattaca agagttggtt ttatctcaag tcagatgggg cttatgctca
    53701 tcaagaatgg caattgattg gaaataagtg gtactacttc aagaagtggg gttacatggc
    53761 taaaagccaa tggcaaggaa gttatttctt gaatggtcaa ggagctatga tgcaaaatga
    53821 atggctctat gatccagcct attctgctta tttttatcta aaatccgatg gaacttatgc
    53881 taaccaagag tggcaaaaag tgggcggcaa atggtactat ttcaagaagt ggggctatat
    53941 ggctcggaat gagtggcaag gcaactacta tttgactgga agtggtgcta tggcgactga
    54001 cgaagtgatt atggatggtg ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa
    54061 gaaagatttg aatgtcggct gggttcacag agatggtaaa cgctatttct ttaataatag
    54121 agaagaacaa gtgggaaccg aacatgctaa gaaaatcatt gatattagtg agcacaatgg
    54181 tcgtatcaat gattggaaaa aggttattga tgagaacgag gtggatggtg tcattgttcg
    54241 tctaggttat agcggtaaag aagacaagga attggcgcat aacattaagg agttaaaccg
    54301 tctgggaatt ccttatggtg tctatctcta tacctatgct gaaaatgaga ccgatgctga
    54361 gaatgacgct aaacagacca ttgaacttat aaagaaatac aatatgaacc tgtcttaccc
    54421 tatctattat gatgttgaga actgggaata tgtaaataag agcaagagag ctccaagtga
    54481 tacagacact tgggttaaaa tcatcaacaa gtacatggac acgatgaagc aggcgggtta
    54541 tcaaaatgtg tatgtctata gctatcgtag tttattacag acgcgtttaa aacacccaga
    54601 tattttaaaa catgtaaact gggtagcggc ttatacgaat gctttagaat gggaaaaccc
    54661 ttattattca ggagaaaaag gttggcaata tacctcttct gaatacatga aaggaatcca
    54721 agggcgcgta gatgtcagcg tttggtatta agcgatgatt tgaaagaggg atgtgatagt
    54781 agcaccctct ttttctttgt tttatgatag ttcatcctcg agtaaattca agatcttgct
    54841 cggaaatgaa gcttatatag tagattgaat atagacaaat accttgtgat tggtaaaaca
    54901 ttttagaaat tcatttacct ttcctaatcg acttggtttc atcttatttc aatctattat
    54961 agtattgggg aatttcttca aaccacatca gcttggtcag ttctacctgc gacctcaaaa
    55021 cttgtgcttt ggtcaagctg ggtttagttt cctagtttgc tgatggattt ccattgacta
    55081 taagcatcca accctctttt tgtcttctaa agaattctta aattatcagt ctattgcaac
    55141 ttttctcatg tgggtcattt ggcttgcaat tgtctttcct tagtagtata ctgaggtagt
    55201 aatcattaag aagtggttac ataaaaataa tgaatgaggt aaaataaaat ggtagaattg
    55261 aaaaaagaag cagcaaaaga tgtcgcaaca ttaacaaaag cagcgccagt agcattggca
    55321 aaaacaaagg aagttttgaa tcaagcagtt gctgatttgt atgtagctca cgttgctttg
    55381 caccaagtgc actggtatat gcatggtcgt ggtttccttg tatggcatcc aaaaatggat
    55441 gagtacatgg aagctcttga tggtcattta gatgaaatca gcgaacgctt gatcacactt
    55501 ggtggaagcc cattctctac tttgacagag ttccttcaaa acagtgaaat cgaagaagaa
    55561 gctggtgaat accgtaatgt tgaagaaagc ttggaacgtg ttctagctat ttatcgctac
    55621 ctcatcactc ttttccaaaa agcgttggat gtgactgacg aagaaggcga tgatgttaca
    55681 aacgatattt ttgttggtgc taaggctgaa cttgagaaaa cagtttggat gcttgccgca
    55741 gaacttggac aagcacctgg tttgtaagaa acaagacaac atagataaat ctgtaggaaa
    55801 tttcttacag attttttcta ttttgtaagc tattccaaac cagtcttttt ttgagttttt
    55861 tgataaaata gtactatcag tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt
    55921 tgggcccagg atgaagaggg tgtgattggt aaggacaatc gtctgccttg gcatttgcca
    55981 gcagaattgc agcactttaa agaaacaact ctgaatcatg ctatcttgat ggggcgggta
    56041 acctttgatg gaatggggcg tcgcttgctt ccaaaacggg agaccctgat tttgacgcgt
    56101 aatccggaag aaaagataga tggggttgct acttttcagg acgtccagtc tgttcttgac
    56161 tggtatcagg ctcaagaaaa gaatctctac attatcggtg ggaagcaaat ttttcaggct
    56221 tttgaagctt accttgatga agtgattgtc actcacattc atgctcgggt ggaaggagat
    56281 acctatttcc ctgaagagct tgacttgtct ctttttgaga cagtttcaag caaattttac
    56341 gccaaagatg agaagaatcc ttatgatttt accatccaat accgcaagag aaaggaagtt
    56401 taatggaacg gagtttattt ggtctattca cggcttttct gtgtttcatc tgctttctgg
    56461 caggagcaca agcttttcgt aaaaagcgtt acgggctttc tatcctcctt tggttaaatg
    56521 cctttaccaa tctggtcaat agtattcatg ctttttacat gaccttattt tagatagaat
    56581 gacagtatag aatggaagga aatcatgtct acaaatagaa aaaatgatat gatggtttat
    56641 tgctcatttt gtggcaaaaa ccaagaagaa gtacaaaaaa taattgctgg caacaatgct
    56701 tttatttgta atgaatgcgt ggagttagct caggaaatca ttcgagaaga attggttgag
    56761 gaagtcttgg cagacttgtc tgaggtgcca aaaccaattg aactcctcca tatcttgaac
    56821 cactatgtaa ttggtcaaga tcgtgccaag cgtgccttgg cagtggcggt ttataaccac
    56881 tacaaacgca tcaatttcca cgatacacgc gaagagtcag aagatgtgga tttgcagaag
    56941 tcaaacattt tgatgattgg cccaactggt tcagggaaaa ctttccttgc ccagaccttg
    57001 gctaagagct tgaatgtacc ttttgctatt gcggatgcga cagctctgac ggaggctggt
    57061 tatgtgggtg aggatgtgga aaatatactc ctcaaactct tgcaggttgc tgactttaac
    57121 atcgaacgtg cagagcgtgg cattatctat gtggatgaaa ttgacaagat tgccaagaag
    57181 agtgagaatg tgtctatcac acgtgatgtt tctggtgaag gggtgcaaca agcccttctc
    57241 aagattatcg agggaactgt tgctagcgta ccgcctcaag gtggacgcaa acatccacaa
    57301 caagagatga ttcaagtgga tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat
    57361 ggtattgaag aaattgtcaa acaacgtctg ggtgaaaaag tcatcggatt tggtcaaaac
    57421 aataaggcga ttgacgaaaa cagctcatac atgcaagaaa tcatcgctga agacattcaa
    57481 aaatttggta ttatccctga gttgattgga cgcttgcctg tttttgcggc tcttgagcaa
    57541 ttgaccgttg atgacttggt tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa
    57601 taccaaacct tgctttctta tgatgatgtt gagttggaat ttgacgacga agcccttcaa
    57661 gagattgcta ataaagcaat cgaacggaag acaggggcgc gtggacttcg ctccatcatc
    57721 gaagaaacca tgctagatgt tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt
    57781 cgcatcacta aagaaactgt cgatggaacg gataaaccga tcctagaaac agcctagagg
    57841 tgactatgga acttaataca cacaatgctg aaatcttgct cagtgcagct aataagtccc
    57901 actatccgca ggatgaactg ccagagattg ccctagcagg gcgttcaaat gttggtaaat
    57961 ccagctttat caacactatg ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg
    58021 gtaaaaccca gctcctgaac ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc
    58081 ctggttatgg ctatgctcgt gtttctaaaa aggaacgtga aaagtggggg tgcatgattg
    58141 aggagtactt aacgactcgg gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc
    58201 atgccccgtc agcagatgat gtgcagatgt acgaatttct caagtattat gagattccag
    58261 tcatcattgt ggcgaccaag gcggacaaga ttcctcgtgg taaatggaac aagcatgaat
    58321 cagcaatcaa aaagaaatta aactttgacc cgagtgacga tttcatcctc ttttcatctg
    58381 tcagtaaggc agggatggat gaggcttggg atgcaatctt agaaaaattg tgaggaaaag
    58441 aaaatggcaa aaacaattca tacagataag gccccaaagg ctatcggacc ctatgttcaa
    58501 ggaaaaatcg ttggcaacct tttgtttgct agcggtcaag ttcccctatc ccctgaaact
    58561 ggggaaattg taggagagaa tatccaagaa cagacagagc aagtcttgaa aaacatcggt
    58621 gctattttgg cagaagcagg aacagacttt gaccatgttg tcaaaacaac ttgcttcttg
    58681 agcgatatga acgactttgt tccttttaat gaggtttacc aaacggcctt caaagaggaa
    58741 ttcccagctc gttcagctgt ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt
    58801 gaagtcatcg cagagattgg ataagctagt tgaagtttgg tgttgccaaa cttcttttga
    58861 tataaggaga aaaagatgac aaagaaacaa cttcacttgg tgattgtgac agggatgagt
    58921 ggcgcaggga aaactgtagc cattcagtcc ttcgaggatc taggttattt caccattgat
    58981 aatatgccgc cagctctctt gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat
    59041 cctaagttgg ccttggtagt ggatatgcgt agccgttctt tcttttcaga gattcaagct
    59101 gttttggatg agttggaaaa tcaagatggt ttggatttca aaatcctctt tttggatgcg
    59161 gctgataagg aattggtcgc tcgttacaag gaaaccagac ggagtcaccc actagcagca
    59221 gacggtcgta ttttagatgg aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat
    59281 atgagccaaa atgtggtgga tacgactgaa ctcactccac gtgagctgcg taaaaccctt
    59341 gcagagcagt tttcagacca agaacaagcc cagtctttcc gtatcgaagt catgtctttc
    59401 ggatttaaat atggaatccc gattgatgcg gacttggtct ttgatgtccg tttcttgcca
    59461 aatccctatt atctaccaga actgagaaac caaacgggtg tggatgaacc tgtttatgat
    59521 tatgtcatga accatcctga gtcagaagac ttttatcaac atttattggc cttgattgag
    59581 ccgattctgc caagttacca aaaggaaggt aagtccgttt tgaccattgc tatgggatgt
    59641 acgggtggac aacaccgtag tgtggcattt gctaaacgct tggtgcagga cttatccaag
    59701 aattggtctg ttaatgaagg gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt
    59761 tcatgagaaa accaaagata acggtgattg gtggagggac tggaattccc gtcattctaa
    59821 aaagtctgcg ggaaaaagat gtggaaatcg cagctatcgt gacggtggca gatgatggtg
    59881 gttcttcagg tgaactccga aaaaatatgc aacagttgac accgccaggt gatcttcgta
    59941 atgtccttgt ggccatgtcg gatatgccta agttttatga gaaggtcttt cagtatcggt
    60001 tctctgagga tgccggagcc tttgctggcc atccattggg aaatctcatc attgctggct
    60061 tgtcagaaat gcagggttca acctataatg ccatgcagtt attgagcaaa tttttccata
    60121 caacagggaa aatttatcct tccagtgacc atcctttgac ccttcatgca gtctttcagg
    60181 atgggacaga agtggctgga gagagtcata ttgtagacca tcgaggcata attgacaatg
    60241 tctatgtgac caatgcccta aacgatgata cgcctctggc cagccgtcga gtagtgcaga
    60301 ccatccttga aagtgacatg attgtcctag ggccaggttc cctctttacc tctattttgc
    60361 ccaatatcgt gattaaggaa attgggcggg ctcttttgga aactaaggca gaaattgcct
    60421 atgtctgcaa tatcatgacc caacgtgggg agacggaaca ctttacagat agcgaccacg
    60481 tggaagtctt gcatcgtcac cttggtcgcc cttttatcga cactgtcttg gtgaatattg
    60541 aaaaagtgcc tcaggaatac atgaattcca accgttttga tgaatactta gtgcaagtgg
    60601 aacacgattt tgtaggtctt tgtaagcaag tttcgcgcgt gatttcatct aacttccttc
    60661 gtctggaaaa tggcggtgcc ttccacgatg gagatttgat tgtggacgag ttgatgcgca
    60721 ttatacaggt gaaaaaatga gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca
    60781 ccatctgagc cggcatgaat tatctgccat tatcaaaatg tctggtagca tcggtctctc
    60841 gacttcgggc ttgactttgt cagttgtgac agaaaatgcc aaactggccc gtcacctcta
    60901 tgagtccttt ctccatttct atgaaatcaa atctgaaatt cgtcaccacc aacggagcaa
    60961 tcttcgcaag aatcgcgtct ataccgtttt tacagatgaa aaggtgcagg atttgttaag
    61021 tgatttgcac ttggcagact ctttctttgg cctggaaaca ggtattgatg aggcgatttt
    61081 atcggacgag gaagcaggtc gtgcctatct ctgtggcgct ttcttggcaa atgggagcat
    61141 tcgtgaccct gagtcaggca agtaccagtt ggaaatcagt tctgtttatc tggaccacgc
    61201 gcaaggaatt gcctcccttc tccaacagtt tttactggat gccaaggtgc ttgagcgcaa
    61261 gaagggggct gtgacctatc tccagcgagc agaagacatt atggacttct tgatagtaat
    61321 aggagccatg caggcacgtg atgattttga gcgggttaag attttgcgag aaacccgtaa
    61381 cgacctcaat cgggctaata atgccgagac agctaatatc gctcggacag tttctgccag
    61441 catgaagacc attaacaata tcagtaaaat caaagatatc atgggcttag aaaatttgcc
    61501 agtagatttg caggaagtgg cgcaactgag gattcagcac ccagactact ctatccagca
    61561 gttagcagat agtctcagca cccctctgac caaaagtggt gtcaatcaca gactcagaaa
    61621 aatcaataag atagcggatg aattataaaa ccacgaatcc tatgtgactc gtggttcttt
    61681 tttataaact ggtagagtgt tttggttgta ctttttgttc agggtcaatg tagttgatag
    61741 cgttgttgac agcagttgga gcttctccga ggcctgtcgc aatcagatca atttttccgt
    61801 catagtagca gcagtcaccg atagcataga tacctgcttg gctggattcc tgtttgctgt
    61861 tgacgataat cttgtgacgg ttgaggtcga gcccccagtt tttaaggtta ccgacagaag
    61921 atttgaaacc atagttgaca aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt
    61981 tgacttttgt gatttcaagt ttatcaagtg tttttccatt tccaaggagt tggctagggg
    62041 cgaatggtgt cttgatggtt acagatgatt cttgcaaggt ttgaacactg tgttccaagg
    62101 cacggaaatt atctctgcgg tgaacaaggg tagttggtgc gattttttca aaagccaaag
    62161 cccaatccac agccgagtct cccccaccaa gaatcgtcac tttcttacca gcgtattgct
    62221 gaatgttaga aacgtggtag tggatatttt catagtcctc aaccccttca agttccagcg
    62281 gacgtggttt gaaggcaccg ccacccatag cgatgataac tgttttagtc aggtgacttc
    62341 ctttggaagt tgtgatggca aattcttctt cttgtttgtc aatctcaaga accgtttcat
    62401 tgagatgaat aggggtatca aatccattta gctgttcaat caagcggtta gtcaactctt
    62461 ctccagtcag gtttgggaag cctggtacgt ctaggatttc cttttcaggg tagagaatag
    62521 caggttgtcc acctagctgg ggaagagagt cgatgatttg aaccttggct tggcgtaggt
    62581 gggcataaaa ggctgcaaaa agcccgacag gaccaccacc cacaatggta atatcataga
    62641 gttgagacat agtttctcct ttgttttttc tagtcagttt attttatcat atttttgttc
    62701 aatgtaaaat ggactaggat agggaaaaaa atgccagaaa atggtataat aggacgaaag
    62761 tgttttgata gggaggatat cagggatgaa ttttcaacaa ttatccaatc tgcaatattg
    62821 gaccagtttg tttgcaagtc catggacgat agctatcaat ctgattgata ttttgattgt
    62881 tgcttatatt ttataccatt ttacaaaagc tattgcagga accaagatta tgattttggt
    62941 acgtggagtt ttggtgttta ttttagctca aatccttgca aatatgattg gtttgactac
    63001 gatttcttgg ttaatcaatc aaattattac ttatggggtt attgcggcgg ttgttatctt
    63061 ctctccagag attcggactg gtttggaacg tttgggaaga gcgacagatt tcttttccaa
    63121 tgcccctatt agtgctgagg aacagatgat tcgtgccttt gttaagtctg ttgaatacat
    63181 gagtcctcgt aaaatcgggg ccttggttgc tattcagcgt gtacgtacct tgcaggagta
    63241 tatgtcgaca ggaattccct tggatgctaa gatttctgca gaacttctca ttaacatttt
    63301 tattcccaac actcccctac atgacggtgc ggtgattatc aaagaagaac gtatcgctgt
    63361 gacgtctgcc tatctgccct tgacaaaaaa cacagggatt tccaaggaat ttgggaccag
    63421 acaccgggcg gctatcggtt tatcagaagt ctcagatgcc ttgacttttg tcgtatcaga
    63481 ggaaacggga ggaatttcga taacctataa tggaaggttt aagcacaacc taacacttga
    63541 tgaatttgaa acagaattac gtgaaatctt acttccaaaa gaggaagtgg gtcttagttt
    63601 taaagaacga ttgctaggag gatggaaaca tgaaaaaaaa tagtttatat atcatatcct
    63661 cactcttttt tgcttgtgtc ttatttgtct atgctacggc gacgaatttt caaaacagta
    63721 ccagtgctag gcaggtaaaa acggaaacct atactaatac agtaaccaat gtccctattg
    63781 acatacgcta taatagtgat aagtatttta ttagcggttt tgcttcagaa gtatcagtgg
    63841 tcttgactgg tgcaaatcgc ctatcgctag ctagtgaaat gcaagaaagt acacgtaaat
    63901 tcaaggttac tgctgaccta acagatgccg gtgttggaac gattgaagtt cctttgagca
    63961 ttgaagattt acccaatggg ctgaccgctg tggcgactcc gcaaaaaatt acagtcaaga
    64021 ttggtaagaa ggctcagaag gataaggtaa agattgtacc agagattgac cctagtcaaa
    64081 ttgatagtcg ggtacaaatt gaaaatgtca tggtgtcaga taaagaagtg tcgattacga
    64141 gtgaccaaga gacattggat agaattgata agattatcgc tgtcttgcca actagcgaac
    64201 gcataacagg taattacagt ggttcagtac ctttgcaggc aatcgatcgc aatggtgttg
    64261 tcttaccggc agttatcact ccgtttgata caataatgaa ggtgactaca aaaccagtag
    64321 caccaagttc aagcacatca aattcaagta caagcagttc atcggagaca tcttcgtcaa
    64381 cgaaagcaac tagttcaaaa acgaattaaa aatagaaaag gattttataa caatgggtaa
    64441 atattttggg actgatggag tccgtggaga agctaaccta gagctaacac cagaattagc
    64501 ctttaaacta ggacgttttg gaggctatgt tcttagtcaa catgaaacgg aagcgccgaa
    64561 agtctttgta ggacgtgaca cacgtatttc aggggaaatg ctggaatcgg ccttggtggc
    64621 aggtctcctt tcagtaggga ttcacgtata caaacttggt gtccttgcaa caccagcagt
    64681 agcttacttg gttgaaactg aaggagcaag tgccggtgtc atgatttctg ctagccacaa
    64741 cccagccctt gataacggaa tcaagttctt tggcggtgat ggcttcaaac tagatgatga
    64801 aaaagaagca gaaattgaag ccttgctaga tgctgaggaa gacactcttc ctcgtccaag
    64861 tgcagaaggc ttaggaattt tggtagatta tccagaaggc ttgcgtaagt atgaaggata
    64921 ccttgtttca actggaactc ctcttgatgg aatgaaggtt gccttggata cagctaatgg
    64981 agcagcttct accagtgccc gtcaaatctt tgcagacctt ggtgcccaat tgacggttat
    65041 cggggaaaca ccagacggtc ttaacatcaa ccttaatgtt ggttcaacac atccagaagc
    65101 ccttcaagaa gtggtcaaag aaagtgggtc agctattggt ttggcctttg atggagacag
    65161 tgaccgcttg attgctgttg atgagaatgg tgacatcgtc gatggtgaca agattatgta
    65221 catcatcgga aaataccttt ctgaaaaagg acaattggct caaaatacaa ttgtgacaac
    65281 tgttatgtct aaccttggtt tccacaaggc cttgaatcgc gaaggtatta acaaggcagt
    65341 tactgcagtt ggtgaccgct acgttgttga agaaatgaga aaatcaggtt acaaccttgg
    65401 tggtgaacag tctggtcacg ttatcttgat ggattacaat accacaggtg atggtcaatt
    65461 atcagcagtt caattgacta aaatcatgaa ggaaactggt aagagcttat cagagttggc
    65521 ggcagaagta acgatttatc cacaaaaatt agttaatatc cgagtggaaa acgtcatgaa
    65581 ggaaaaggcc atggaagtgc cagctatcaa ggccatcatc gagaagatgg aagaagaaat
    65641 ggcggggaac ggccgtatcc ttgttcgtcc aagtggaaca gaacccctct tgcgtgttat
    65701 ggcagaagcg cctacaacag aagaagtaga ctactatgtt gataccatca cagatgtagt
    65761 tcgtgctgaa attgggattg actaaatcct agaaaactag atgaaaataa aaaattatgg
    65821 tacaatagct tataatattg tagccgatgg agaaagacat gaatcttaaa cgtgaacaag
    65881 aatttgttag tcagtatcat tttgatgcgc gtaattttga atgggaaaat gaaaatggag
    65941 ctcctgaaac caaggtggat gtgaatttcc aattgctcca acatgaccaa gaaaatcaag
    66001 tgacttcctt gattgtcatc ttgagcttta tgattgtatt tgataagttt gtcattagtg
    66061 gaacaatctc acaagtaaac catatcgatg gccgtattgt caatgaacca aatgaattga
    66121 accaagaaga ggtggaaacc ttggctcgtc catgtttgaa catgctcaat cgtttgactt
    66181 acgaagtgac tgaaattgca ttagacttac caggaattaa tttggagttc taatatgaaa
    66241 ttagctgttt tcacagattc ctctgcttat ctcagtgcag agatcttgca aagagaagac
    66301 ttgtttgtct tggatattcc tgtcaatatt gatggtgagg aatatgtcga aggcatcaat
    66361 ctgtctgctg aggaatttta ccaaaaaatg gctcaggctt ctgaattgcc taagaccagt
    66421 caaccaagta ttgccaagtt agatgagatc ttaacttcgc tcaaagaaca aggctataca
    66481 catgccttgg ggcttttcct atcttctgga atttcaggtt tttaccaaaa tatccagtat
    66541 atggtcgatg actatgaggg cttaaccatt gctttcccag acactttgat tacaagtgct
    66601 cccctaggca tcatggttga aagtgtcttt aattggcgtg atcagggcga tgattttgcc
    66661 agcattcagg ataagctagc cattcaaatc agccgtacgt cagcctttat catggtagat
    66721 gacttggatc atttggtaaa aggtggacgc ctttcaaatg gggctgccat tttgggcaat
    66781 ttgcttagca ttaagccaat cctttatttt aacgatcaag gtgtgattga agtttacgaa
    66841 aaagttcgta ctgaaaagaa ggccaccaag cgcttaattg aaattatcaa ggaaacaacg
    66901 gcttcaggtc aataccgggt cattgtcatt catgggaatg ctcctgaaaa ggctgaagaa
    66961 ttgcgtcagc acttgcttga ttttggcttg ggttcggatg tttcacttgc tacatttggt
    67021 agtgtcattg gaacgcacct aggagcagga agtattgctc tgggttatat tccagtgatt
    67081 tagttggcgc ttctaggcta gttaagatgc cttgtatctt agaaattgaa cacggactac
    67141 ctgcctcttg aaaaaagatg cctgtcttgc ctttcgtgga aagtcagtgc cattccctat
    67201 ttttcagagg cagctaaggt cctttgtatc ttgataattg aacacgcctg gaaccctgtg
    67261 tgaaaaagat agttcttcca agaagtagac acttcttgat tggaattcct attttcactt
    67321 tgtgttctta cggactttgt atcttagaca ggagtagaga tgagtattcg agtaattatt
    67381 gccggtttta agggaaagat gggccaggct gcttgtcaga tggtattgac tgatccagac
    67441 ttggacttgg tggcagtttt ggatcctttt gagtctgagt cagaatggca gggtattcct
    67501 gttttcaagg ataaggctga tttagctggt tttgaagcgg atgtctgggt agattttact
    67561 actccagctg ttgcctacga aaatacacgt tttgctcttg aaaatggctt tgctccagta
    67621 gttggaacga ctggtttcac gagtgaagaa attgcagagc taaaagaatt ttctcgtgcc
    67681 caagacttgg gtggcctgat tgcccctaac tttgccttgg gtgctgtctt actcatgcaa
    67741 tttgcgacgc aggctgccaa atatttccca aatgtggaga ttattgagct ccatcatgac
    67801 aagaaaaagg atgctccgag tggaacagcc attaaaacag ctgagttgat ggcagaggtt
    67861 cgagagtcca ttcagcaagg tgcagcagat gaggaagagc tgattgctgg tgctcgtggt
    67921 gctgactttg atggtatgcg catccactca gttcgtttgc caggcttggt agctcatcag
    67981 gaagtcatct ttggcaatca gggagaaggg ttgaccctcc gtcatgactc ctatgatcgc
    68041 atctccttca tgacaggagt caatttggga attaaagaag ttgtcaagcg tcatgagctt
    68101 gtctatggat tagaacactt attatgagat taatgcaaat gccttctgaa tttcagaagg
    68161 ctttaccagt attagaaaaa attaaagaag caggctttga ggcttatttt gttgggggct
    68221 ctgttcgaga tgcccttctc catagcccta tccacgatgt ggatattgcg acgtcttctt
    68281 atccagaaga gaccaagcag atttttccgc gaacagccga tatcggaatc gagcatggaa
    68341 ccgtcttggt cttagatggg gatgaggagt atgaggtaac aacctttcgg acagaggatg
    68401 tctatgtgga ctatcgcaga cccagtgcgg tttcctttgt gcgctcgcta gaagaagacc
    68461 tcaaacgccg tgatttcaca gtcaacgcct ttgccttgga tgagacagga gaaatcgttg
    68521 acttgttcca tggtttagaa gatttggaaa agcaagtctt gcgagcagtt ggagtggcta
    68581 gtgagcgttt caacgaagat gctttacgga ttatgcgtgg tttccgtttt caggctagtc
    68641 ttggttttgc acttgagcca gaaacattta aagctatgaa gaccttgacg ccgcttttgg
    68701 agaaaatttc tgtagagcgt accttcgtcg agtttgataa actcttgctg gctccatttt
    68761 ggagaagggg cttggcttcc atgattgaga gtcaagctta tgactatctc cctgatatgg
    68821 catctagcca ggacaagctc aacagactgt ttgatttgga gactgatttt acttttgaat
    68881 cctctgaaca agcctgggcg gctttactat gggctttgga gattgaaaat gcgcagtcat
    68941 ttttgaaatc ttggaagacc tcacgccagt ttgccaagca agttcaggat ttgctgatta
    69001 ttttggctct gcgtgaaaat ggagaattga gtaagcgtga ttgttatcgc tttgacttgg
    69061 atttactttt acaggctgaa aatcttcgtc aagctcaggg aaaagaagtc aacccacaag
    69121 tcattaaaga aacctaccag agcttgacta ttcatgataa gaaagaaatc caaatcaacg
    69181 gcggtatttt gatcaaggaa tatggctatc agccaggccc agacttggga gagattttaa
    69241 cagagattga gtttgccatt gtcgatggag aattggagaa taatcgtgaa gccatccatg
    69301 cttacctgag ggagaaaaaa tgagtgattt tatcgttgaa aaactaagta aatccgttgg
    69361 tgacaagacc gtttttaggg atatttcctt tattatccat gacttagaca gaattggttt
    69421 aatcggtgtc aatgggactg gcaagaccac ccttttggac gtcctttctg gtgtttctgg
    69481 atttgatggg gatgtcagtc ctttttcagc taaaaatgat taccagattg gttacttgac
    69541 tcaggatcct gattttgatg atagaaagac agttttggat acggttctat ctagtgaact
    69601 caaggaaatc cagctcattc gtgagtatga attgattatg ctcgactata gtgaggacaa
    69661 gcaggcgcgt ttggaacgtg tcatggcaga gatggactct ctccaagctt gggaaattga
    69721 gagtcaggtc aagaccgttc ttagcaaatt gggcattcaa gacttatcta ctcctgttgg
    69781 ggaattgtca ggtggtctga gaagacgggt acagttggca caagtcttac ttggcaacca
    69841 cgaccttttg cttttggatg agccgaccaa ccatctggat attgcgatta ttgagtggct
    69901 gaccctcttt ttgaaaaatt ctaagaagac cgtccttttt atcactcacg atcgttattt
    69961 cttagacgct ttgtcaacac ggattttcga gttggagcga gcaggcttga cagaatatca
    70021 gggcaattac caggactatg ttcgccttaa ggcagaacag gacgagcgcg atgcagctct
    70081 acttcataaa aaagaacaac tctacaaaca agaactggcc tggatgcgca gacaaccgca
    70141 ggcacgtgcg accaagcaac aagctcgtat caatcgtttc catgatctga aaaaggaagt
    70201 ttcaggcagt agtgctgaga cagacttgac tatgaacttt gaaaccagtc ggattgggaa
    70261 gaaagtcatc gagtttcagg atgtttcctt tgcctatgaa aataagccca ttttgcaaaa
    70321 ttttaatctc ttagttcagg ctcaagaccg tattggaatt gttggggaca atggtgttgg
    70381 aaaatcaacc ctacttaacc tgattgcagg aagtcttgag ccgacagcag gacaagttgt
    70441 gattggggaa actgttcgca tcgcctattt ctctcaacaa attgagggtt tggatgaaag
    70501 caagcgtgtg atcaattacc tgcaggaagt ggcagaggag gtcaagacca gtggtggttc
    70561 tacgacttcc atcgctgagt tgctggagca attcctcttc ccacgttcga cgcatgggac
    70621 tttgattgag aaattgtcag ggggtgagaa aaaacgtctt tatctcctca aactgctttt
    70681 ggaaaaacca aatgttcttc ttttagacga gccaaccaat gacctagata ttgcaacttt
    70741 gacagtctta gagaatttct tgcaaggttt tgcaggtccc gttttaacag tcagtcacga
    70801 ccgctatttc ttggataagg tagcgaccaa gattctcgct tttgaggatg gcaagattcg
    70861 tcctttcttt ggtcattaca ccgactatct tgatgaaaaa gcttttgaaa cagatatggc
    70921 caatcaagtg caaaaggccg aaaaggaaaa agtggtcaag gttcgagaag acaagaaacg
    70981 catgacctac caagaaaagc aggagtgggc aagtattgaa ggtgatattg aaaccttgga
    71041 aaaacgtatc gctgctattg aagaggaaat gcaggctaac ggctctgact ttggtaagct
    71101 ggctactctc caaaaagaat tggatgagaa aaatgaagca ctccttgaaa aatacgaacg
    71161 ctatgagtat ctcagtgaat ttgatagtta agactattcg aaaatcaaag tgcaaactat
    71221 gtcggcttca cattgccgac tcaagtacag cctgtgactg gcttcctaat ttgcactttg
    71281 atttttattg agtataaaag aatagaaaaa tcccgtctca tgaaaggatt tctctattct
    71341 tttttggttt cttgatgaaa gatattttgc caggtttcgt ggcgacgcca gatactggta
    71401 tggatgatac catctaactc atagcagatg agtttggttt tttgactgat ggaagtaatt
    71461 tgaatgtcct tgatagcaga atttaactct tttttggtct tataagcctc tttatccatc
    71521 tgctctccat cttggcgaat atagacaaaa tcatcagtca agagttcttc tagttggttt
    71581 ccttggtcaa tcaattgttc acgcataagc aattttttat agacattgtc taaaatttca
    71641 tcctcaggga taggtgctgg ttcgatatgg acatcggtat caaagacgcc aaaacgctcc
    71701 tccagcatag actcgacctg atccgcgatt tcatggcttt caaaaacaga caagtcagga
    71761 ttcatctcta gtgtaatatc caggtagatg ttgctaccgt aggtgcgacc tctttgcgat
    71821 ttgaccttgc tgattttggg aatttccatg atagcctttt ggtagtcctc gagcaggcgg
    71881 tcgtcaaagc catctgaaag actaaaggaa gactcgatga agatatcata ggcagtcttc
    71941 aagataaaga aagtgatgat gatagcaacc agtttatcca caatcggata attaaaacta
    72001 ctagctagga tggcaatggc ggttccaagt gaggtaacag cgtcagaaag attgtcctta
    72061 gcagctgcct tcagcgcctt ggagttggat ttcttactga ggcgagtatt gtagagatag
    72121 accacaaaca taatcgctgc agaaatgatt cctagagttg caccaagagg atcaatgacc
    72181 gtttcttccc gactgagaat cttttgaatg gtatctctta gaacatcgaa accgacatag
    72241 aacatgatga tagaagtgat caagcttgcc aaatcttcaa tcttccaatg accaaaacgg
    72301 tggtcacggt ctgcaggctg gcgcgccatc cgaatcccga ttaagagggc tacatttcca
    72361 atgatgtccg atacgttatt aaaaccatcg gccaccaaac tggatgaatg aaggagatga
    72421 ccagctgcta atttggctgc agacaagatc aaataggtcg aaatactgat aatggctcca
    72481 cgctcagcta acttgagatt tgagatagat tgcttcattc aacttccttt ctagtcacat
    72541 agcattctac cattatactg gttttcaagg aaaaattcaa ataaggcagt ttttactctt
    72601 tgaaaactcc ccaaaatttg gtataatggt actactcaag ggagtagctg gcagaaacct
    72661 gtgatagtgt cgtcattccg aattttatgc tgaaaagtat gctttccggc cctatcttaa
    72721 acagcgagac ttgttatgat taacaggtct ctttttgttt gtcgtgaaaa gatatgacag
    72781 aaagagagtc tgttttgcac acaatgtcaa ggaggagaca catgtcaaaa gaacaaaaac
    72841 gccaagcgtt ttatactcag agccctgaag aggtcttgca ggctgtggat gcgaccgagc
    72901 aaggtttgtc atcaagtgag gcggaaaagc gccttgccga atttgggcac aatgaactcg
    72961 aagaaggcga gaaacgatca atcttggtca aattcatcga gcaatttaag gatttgatga
    73021 ttatcatcct agttgcggca gcaatcttgt cagtcgtgac ttctggtggg gaagatatcg
    73081 cagatgccat tatcatccta gctgtggtta tcatcaacgc tgcctttggt gtttaccaag
    73141 aaggaaaagc tgaagaagct attgaagccc tcaaatccat gtctagtcca gttgcccgcg
    73201 ttcttcgtga tggacacatg gcagagattg actctaaaga attggtacca ggcgatatcg
    73261 ttgcccttga agcaggtgac gtggtaccag cggacctacg tttgatagaa gccaactctc
    73321 ttaaaattga agaagcagcc ttgacaggtg aatctgtacc agtcgaaaaa gacttgtcag
    73381 tcgagcttgc gacagatgct ggtattggtg accgtgtcaa catggccttc caaaactcaa
    73441 acgtaaccta tggtcgtggg atgggtgttg ttgtcaatac aggtatgtac actgaagttg
    73501 gtcatattgc tggtatgctt caagatgcgg atgagactga tacaccactc aaacaaaatt
    73561 tgaacaacct ttctaaggta ttgacctatg ctatcttggt cattgccctt gttacttttg
    73621 tagtgggtgt cttcattcaa gggaaaaatc cacttggtga gttgttgact tctgttgccc
    73681 ttgccgttgc agccattcca gaaggacttc ctgctatcgt taccatcgtt ctttctcttg
    73741 gtactcaagt tttggccaaa cgacattcca tcgttcgtaa gttgccagca gttgaaacac
    73801 ttggttcaac tgaaatcatc gcttctgata agactggtac gctgactatg aacaagatga
    73861 cagtcgaaaa agtcttctac gatgcggttc tacatgactc agctgatgat attgaactag
    73921 gtcttgaaat gccactactt cgttcagttg tcttggccaa tgatacgaaa atcgatgtgg
    73981 aaggtaactt gattggtgac ccaaccgaaa cagcctttat ccaatatgcc ttggacaagg
    74041 gctatgatgt caaaggtttc ttagagaaat atcctcgtgt agctgaattg ccatttgact
    74101 ctgaccgtaa gctcatgtca acagttcacc cattgccaga tggtcgtttc cttgtagcag
    74161 tcaagggtgc gccagaccaa ctcttaaaac gttgtcttct tcgtgataag gctggggata
    74221 ttgctccgat tgatgagaag gttacaaatc tcattcatac aaacaattct gaaatggctc
    74281 atcaagcctt gcgtgtcctt gcaggtgctt ataagattat cgatagtatt ccagaaaatc
    74341 tcacttctga agagcttgaa aatgatttaa tttttactgg tttgattggg atgattgacc
    74401 ctgaacgtcc tgaagccgct gaggctgttc gtgtggctaa ggaagcggga atccgtccaa
    74461 ttatgattac aggtgaccac caagacacag cggaagccat tgccaaacgt ttgggaatca
    74521 ttgacgcaaa cgatacagaa ggtcacgttt taactggtgc tgaactcaat gaactgtcag
    74581 atgaagaatt tgaaaaagtc gttggtcaat actctgttta tgcccgtgtg tctccagaac
    74641 acaaggttcg tatcgtcaag gcttggcaaa aacaaggtaa agtcgttgcc atgacaggtg
    74701 atggtgtcaa tgacgcgcca gctctgaaaa cagccgatat cggtatcggt atgggaatca
    74761 ctggtacaga agtttctaag ggggcttctg acatgattct tgcagatgat aactttgcga
    74821 ctattatcgt cgcagtggaa gaaggacgta aggtcttctc aaacattcaa aagactattc
    74881 agtacctact ttctgctaat actgctgaag tattaaccat cttcctatca accttgtttg
    74941 gttgggatgt cttgcagccg gttcatcttt tgtggatcaa cttggtaacg gataccttcc
    75001 cagctattgc tcttggtgtt gaacctgcgg agcctggtgt catgaatcat aaaccacgtg
    75061 gacgcaaggc aagcttcttc tcaggtggtg ttttgagttc tatcatttat caaggtgtac
    75121 tccaagcagc tcttgttatg agtgtttatg gccttgcgat tgcttaccca gttcatgtgg
    75181 gtgacaatca tgctattcat gcagatgccc taacgatggc ctttgcaacc cttggtttga
    75241 ttcagctctt ccatgcctac aatgtcaagt ctgtctacca atccatcttg acagttggcc
    75301 cattcaagtc taagaccttt aactggtcca tcttggtatc ctttatcctt ctcatggcaa
    75361 caatcgttgt agaaccgctt gaaggaatct tccacgtaac caaactagac ttgtcacaat
    75421 ggggaattgt tatggctgga agcttttcaa tgattatcat cgtcgaaatc gttaagttta
    75481 ttcaacgcaa actcggtttt gacaaaaatg cgatttaagg gaggtttcgg atgtcagcat
    75541 atcaattacc gaccgtatgg caggatgaag ctagtaatca aggagctttt acggggctaa
    75601 acagaccaac agcaggtgcc cgtttcgaac aaaacttgcc aaaaggagaa caagcttttc
    75661 agctttattc actgagaaca ccaaatggtg tgaaggttac tatcttattg gaagaattac
    75721 tagaagctgg ttttaaggaa gcggcttacg acttgtataa gattgctatc atggatgggg
    75781 atcaattcgg atcagacttt gtgaagctca atccaaattc caagattcca gccttattgg
    75841 accagtcagg tactgaagat gtaagagtct ttgagtctgc tcatattctt ctttaccttg
    75901 ctgagaaatt tggagccttt ttaccaagta atcctgtgga aaaggtagaa gttttgaatt
    75961 ggctattctg gcaagcaggt gcagcacctt ttctaggtgg gggatttgga catttcttca
    76021 attatgctcc tgaaaaattg gaatatccta ttaaccgttt tacgatggaa gtgaaacgcc
    76081 agttggattt attggataag gaattggctc agaaacctta tattgcaggc aatgactata
    76141 cgattgcaga tattgctatc tggtcttggt atggacagtt agttcaagga aatctttacc
    76201 aaggttctgc aaaattcttg gatgcctcaa gttatcaaaa tctagtaaaa tgggcagaaa
    76261 aaattgccaa tcgtccagct gttaagcgtg gcttggaagt aacttataca gaaattaaat
    76321 agcaaaaaag tcatcttcgg atggcttttt gctacagttg agggaaaggg tttgcagtta
    76381 tcggcttttg tgctataatt gctataatat agtaaaaagc aagaggagtg tgaggaagtg
    76441 gaaaagaaaa ttgtgaagga tatcttattt ttatctcaag tgtctcagcc ggcaagtcag
    76501 gaggaccttt atcttgccag agatttgcag gatacactct tagcaaatcg tgatacctgt
    76561 gttggtctag ctgccaatat gattggggtg cagaagcgcg tgattatctt taatcttggc
    76621 ttggttcccg tggtcatgtt taacccagtg cttctgtcct ttgaaggatc ttatgaggca
    76681 gaagaaggct gtttgtcctt ggtaggtgtg agatcaacta agcgttatga aaccataagg
    76741 cttgcctatc gtgacagcaa gtggcaggaa cagaccatta ccttgacagg cttcccagct
    76801 cagatttgcc agcatgagct ggatcacttg gaaggacgaa ttatttagga ggaaagcaaa
    76861 tgaaacgaat agtctttgaa cttattttta tcgcaacgac ctggtatatc tttttaccgc
    76921 cccttaacct gaccagctgg gaatttctct tcttcctctg tgggcatttg ttagttgtgg
    76981 caatcttatt tggctttggc aaggggataa accttgtcaa aacggttcat gtgcgccacg
    77041 gtaaggcgga agctgcctta aatcttgagg gtttcaaaat caatcggtta gggaaaattc
    77101 tgttagcttc gattggagga attcttctct tggcagcttt ggtttccttg gtaacttcta
    77161 gcatgtttca ggctaaaaat tatgccaatg tagtcacggt tacggaaaaa gactttactg
    77221 aatttcctaa gagtgacacc agtaaggttc ctatcctaga tagaagtact gctgaaaaaa
    77281 ttggagaccg ctacttgggt tccctaaccg ataaggtgtc gcaatacgta gcggcagata
    77341 cctataccca attgacaatt gatgggaaac cttatcgggt cacaccacta gaatatgcag
    77401 accctatcaa atggtttaac aatcaagcca agggaattgg tgagtatatc aaggtggaca
    77461 tggtaactgg aaatgcggat ttggtggact tgaagacacc aatcaagtat tcagactcgg
    77521 agtattttaa ccgtgatgtc aaacgtcacc tgcgcttgaa gtacccgacc aaaatcttta
    77581 aaactccatc ttttgaggtg gacgatgagg gcaatccttt ctatgtagca acggtttacc
    77641 aaaagcaatt tggacttgct gttcctcgtc ctgcttcagt cattatcttg gatgctacaa
    77701 atggagaaac caaggaatac agcttatcag atgttccaga atgggtggac aggatctatc
    77761 cagcagagga aaccattgag caaattaact acaacggcaa gtacaaggac ggtttcttga
    77821 atgccatgat ttccaagaaa aacgtgaccc agactaccaa gggctataat tacttgtcta
    77881 tcggtaatga catctatctc tacacaggtg tgacgtcggc taatgcggat gagagtaatc
    77941 ttggtttcat ccttgaaaat atgcgaacag gagaaatcac taagtatagc ttggcttctg
    78001 cgacagaaga atcagcccgt gaatcagcag aaggtgctgt tcaggagaaa tcctacaaag
    78061 caaccttccc aatcctcatc aacctcaatg acaagcctct ctacatcatg ggcttaaagg
    78121 acaatgctgg cttggtcaaa gagtacgccc tggtagacgc agtcgagtac caaaatgtta
    78181 tcgttgctac tacagtggaa gagatgctca gcaagtatgc caataaaaac gaccttgaaa
    78241 ttgacaatgc aacgacagaa agcatcaagg gagtagtagc agacctcaaa tcagctgtta
    78301 tcaagggcga caccgtctac ttctttaaag ttgatggcaa gatttacaag gttaaggcct
    78361 cagtatccga tgaccttcct taccttgaaa atggtagaac cttcgaaggt caagtaggaa
    78421 aagacagcta tctcaagacc tttaaagtac agtaatactc tgcgaaaatc tcttcaaacc
    78481 acgtcaactt tatctgcaac ctcaaagctg tgctttgagc aacctgcggc tagtttccta
    78541 gtttgctctt tgattttcat tgagtataaa aaaggtttat ttaagaaata tatgttatag
    78601 taaaataaat taagactaat ggaggacaaa gaaatgggtt tttatttgat ggttgcttca
    78661 atgctactcg gactgctcgc tttgaagata ggtttttctc agttcaagga gaacaaagat
    78721 aaattcttat ctatcttaac aagtttagct gggctagccc ttgttctcgt ggctgtctgg
    78781 ttaggatggc ccaaataaat agaaaaacct cggtcaaacc gaggtttttc agatgaattt
    78841 cttggttgtg gctaaaaaat atgctacact atcaatatga agattttaat ccctacagca
    78901 aaagaaatga atacagactt gccgagtatc gagacaactc ttttaagatc agaaagtcag
    78961 gctgtacttg atgccttggc tctctattct gccagtcaat tggaaagttt ctacaaggta
    79021 tcagctgaga aggctgcgga agaatgtcaa aatatccaag ctttgaaaag gcaaactgct
    79081 caacactacc cagccttgaa gctttttgat gggcttatgt accgtcatat caagagagac
    79141 aaactgaccg aggtagaaca agcctatctt gaaaatcatg tcttcattac ctcggctttg
    79201 tacggagtcg ttccagcctt gtcgcctatg gcacctcacc gtttggattt tttgatgaaa
    79261 ttaaaagtcg ctggtaagac tttgaagagc cattggaagg cagcctatga tgaagctgtg
    79321 aagcaggaag aagtgatttt ctctctcttg tcatcagagt ttgagactgt attttctaag
    79381 gaaatcagag caaagatggt gaccttcaaa ttcatggagg atagaggcgg tcagctgaag
    79441 attcactcaa ctatctccaa gaaagcgcgc ggggcctttc taacagcttt aatagaaaat
    79501 caagtacaaa ctgtggggga agcacgtcgc ttgaactttg ctggatttgt ttaccgagaa
    79561 gatttgtcac aaccacaggg attggttttt gtaaaggaag tatagaaatc agataagaga
    79621 aaagtcagca cgattatgct gacttttttg ataacttata aagtattgga caaatgaatc
    79681 tcatttgata aggtgttaag atgattaacc aaattcatga ttgacagatg atttcggcaa
    79741 ataaacttct tggtaatccc tgaaatatag aaattagaca cgatgatatc gtaatctgtc
    79801 tgatttaaaa tctcaggact tgtttttaat tcatcccaaa tatcgaaggt aaagcggtta
    79861 ttacagtaat aggaaagcat atcaacaaag gtaagggata tagcatggtc aaagttactg
    79921 ataatcaaaa ccttgatagg tggtcgattt tctaacaact gagtagagag gttttcagca
    79981 tgggttaaga tggtgtacat caagtgttcc aactgttcag gatggtcatg ctgtccaatt
    80041 gcctgacggt attgagccag ttcttgacgc gcacttccca taaagtctgg gaagtaaact
    80101 tcaaattttt taatcgtcaa tgctttttgt tcaaataaga ttggggtaga aaagatttcc
    80161 tgtctttcaa agaaagcagt gttgtgtaaa tgccaaatca gctcatcgtg gttagtaaaa
    80221 gtaatcttat attgttttga taggcgttct aatatttgac taagtaattg gtaagagtat
    80281 cttgcttgac tgttatcttc taaagagttg aagaattctt gaggatctag gaaaatatca
    80341 ttctgaagaa aagaaataaa aatttgagcg attgtatctg gagtcatttc aagcccaaaa
    80401 tgtttagaga aataagcaag tgtctcctgg aaatttggaa tgctctttaa aagaggataa
    80461 tattctttgt aaaagtggtt ggggaggtca atgaagtgac catttttaac cctgtggata
    80521 ctgatagcta tcatcagttt gtacattcta taaattgaaa atcgcattgg ataattcgtg
    80581 attttataga agaagtcagc aaactctgtt aaatcttcct caggaaggtc aggaaaaggc
    80641 caatctagga aataatagcg ctcagaaaag tattgggcaa aaaagtaacg aatatcgatc
    80701 tcatttccac gtatctcgga tggagtaaaa gataattcaa tttgaaactg agatgaaaga
    80761 acctttgtaa tatttctgcc cagtcgatag aggttggcac tactaaagta aagattttct
    80821 attgttcgat aaataggtag cccctcattg aagaacatat actctagtaa ttgaaaagat
    80881 tgagaattag caagaaaata ttgataaata tcttctacac tagtgttaac ttctaaatct
    80941 atcatgattc cgttaacaga agattggatg ttaatagatg gaaaggcaat acgtaattca
    81001 tttaaatcac tttttaagat tcgttctgta catcctaatt tttcggctag ttcatgtaat
    81061 ttcatccaat tacgattctg aattagggtt tccattaagc gtaattgtct ttgaactttt
    81121 gtggataaaa ggtttctcat acgggtattt cctccataat tcattatatc tttttttgtc
    81181 taagtagtat aaaaaaatta gagcaagaaa attgtcgtta gtaatcggaa aaattagaat
    81241 aatataagtg gcttttaagt gcaaaaacag aatatattaa ttgttcagaa aatattgatt
    81301 aatgcctcaa atagttgtac attgtaaact ataaaatact atctaggagt ttaaaatgaa
    81361 acattcacat aaaaaatcat ttgactggta tagcatgcaa caacgttatt ctattcgtaa
    81421 gtattacttt ggtgcagtta gtgtcttgct cggtaccgct ttggtattag gtgcagcagc
    81481 tagtgtccaa acagtacaag cggaagaaaa caaacaagaa actaccaata gtatttctgt
    81541 tggtagggga gaagcagcta ctaaaccagc agaggtttct gcgtctaata aagagaaaac
    81601 ctatgcagct ccaactgtag ctaatccagt agaaacgact ccagttaaaa ctggagaagt
    81661 tactaaacca gcagaaaaag ttgaagaagc aaaagacaaa aaagaggaag taacgcatca
    81721 agatgctatt gacaagtcaa aattgttaac ggctctttcg cgtgctaaaa agttagaaag
    81781 caagttatat acagaagcaa gtgctgctaa cttgcaaaca agtatccaag ctggtcaaag
    81841 cttgcttggg aaagcagatg catctgaagc tgaattatca gcagcagagt catctattca
    81901 atcatctatt attggtctag aacttcgttc taactctaac aaaggaactg tatcagaaac
    81961 gcctgtagca aagaaagcta atatagttga agcgaaggaa gagactaaac cagctgtaac
    82021 aacgactgaa cgttcagctg ttgatagcgc tattttgcca attagcacag ctgctaaagt
    82081 agaaacaact tcagctccag catctactaa tgaaatcttg aaaccaagtt tgagcctttc
    82141 tgatgctcgc caaaatccag ctatccgtaa ggaagatgtt gatagagggt atagtggttt
    82201 tagaacagca ggaagtggct ttagagcggc tggaagtggt tttagagcag ctggaccaga
    82261 aaataaacca atcttaaatc caaataatac tattgcattt tctgacatca gtcagggctt
    82321 acattcattt cgtggtatag gacattcacg tggtggtcgt gaaatccatt atgatgtaac
    82381 gacagtacgt agaggtaata gattgaattt cacaattaaa tactctggtc caggtgaatt
    82441 tgttaataat aattttatct tggataaagg ggatggattt ggaaatcctt caaatgcaac
    82501 gatcacaagt tcaaatccaa gagtaaggga gcaatcaaaa tctattagtc agggtgccaa
    82561 ctacgtatct cactcaggat acagtatgac ctctgctact tcaacaaata cggaacaaac
    82621 tatcagattt agtttgccta tcattaatcc aaatggtgat ttgtctgttc gtttgaaacc
    82681 agttactttt aacgtggacc aaggtggtgg tggtgccgct actagcaatg acccatacag
    82741 taactccaac tattatcata gagcaaatcc actcctcttg gatgcaaacc cttatggtgg
    82801 tactaataat aagactgttt cagaagacat tgacttccaa actgtctatc ttccaactag
    82861 taagttacca gaaggtcaaa ctagattagt tcgagaaggt gaaaaaggac aacgtcaaat
    82921 tacctataaa gtacatcgat ttggtaacga aacactttta ggattgccaa ttagtaatag
    82981 agttactaaa gaagctaagc cacgtattat gcaaattggt gtggctaaag agttaatcga
    83041 tacagtaaaa ccacgtgttg atcaaaataa agttggtgat acaaataacc tcactttcta
    83101 tcttgataac gatggaaacg gtgtttatac tgagggcgta gacgaacttg ttcaaaaaat
    83161 tgctattaaa gatggagcca agggtgaaaa aggagaccaa ggtgaacgcg gtctaactgg
    83221 agctaa
//
LOCUS       DAVLAQ010000002        71483 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000002 DAVLAQ010000000
VERSION     DAVLAQ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.002"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(290..1897)
                     /locus_tag="VXB71_000085"
     CDS             complement(290..1897)
                     /locus_tag="VXB71_000085"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0450267.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDTEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2287..2874)
                     /locus_tag="VXB71_000086"
     CDS             complement(2287..2874)
                     /locus_tag="VXB71_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0450268.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3002..3451)
                     /locus_tag="VXB71_000087"
     CDS             complement(3002..3451)
                     /locus_tag="VXB71_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450269.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3456..3845)
                     /locus_tag="VXB71_000088"
     CDS             complement(3456..3845)
                     /locus_tag="VXB71_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0450270.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3873..4499)
                     /locus_tag="VXB71_000089"
     CDS             complement(3873..4499)
                     /locus_tag="VXB71_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0450271.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4513..5076)
                     /locus_tag="VXB71_000090"
     CDS             complement(4513..5076)
                     /locus_tag="VXB71_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0450272.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5241..5475)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5529..6032)
                     /locus_tag="VXB71_000091"
     CDS             complement(5529..6032)
                     /locus_tag="VXB71_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0450273.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6225..7055)
                     /locus_tag="VXB71_000092"
     CDS             complement(6225..7055)
                     /locus_tag="VXB71_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0450274.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7040..8722)
                     /locus_tag="VXB71_000093"
     CDS             complement(7040..8722)
                     /locus_tag="VXB71_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450275.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8824..9081)
                     /locus_tag="VXB71_000094"
     CDS             complement(8824..9081)
                     /locus_tag="VXB71_000094"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450276.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9088..9636)
                     /locus_tag="VXB71_000095"
     CDS             complement(9088..9636)
                     /locus_tag="VXB71_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0450277.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9651..10499)
                     /locus_tag="VXB71_000096"
     CDS             complement(9651..10499)
                     /locus_tag="VXB71_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0450278.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10687..12036
                     /gene="trkA"
                     /locus_tag="VXB71_000097"
     CDS             10687..12036
                     /gene="trkA"
                     /locus_tag="VXB71_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0450279.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12040..13479
                     /locus_tag="VXB71_000098"
     CDS             12040..13479
                     /locus_tag="VXB71_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0450280.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13604..13861)
                     /locus_tag="VXB71_000099"
     CDS             complement(13604..13861)
                     /locus_tag="VXB71_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEV0450281.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            14621..14791
                     /locus_tag="VXB71_000100"
     CDS             14621..14791
                     /locus_tag="VXB71_000100"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0450282.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            15403..15687
                     /locus_tag="VXB71_000101"
     CDS             15403..15687
                     /locus_tag="VXB71_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450283.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            15680..15918
                     /locus_tag="VXB71_000102"
                     /pseudo
     CDS             15680..15918
                     /locus_tag="VXB71_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16014..16232
                     /locus_tag="VXB71_000103"
     CDS             16014..16232
                     /locus_tag="VXB71_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450284.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(16599..18923)
                     /gene="pflB"
                     /locus_tag="VXB71_000104"
     CDS             complement(16599..18923)
                     /gene="pflB"
                     /locus_tag="VXB71_000104"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0450285.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            19317..20378
                     /gene="dinB"
                     /locus_tag="VXB71_000105"
     CDS             19317..20378
                     /gene="dinB"
                     /locus_tag="VXB71_000105"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0450286.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(20525..21370)
                     /locus_tag="VXB71_000106"
     CDS             complement(20525..21370)
                     /locus_tag="VXB71_000106"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0450287.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            21625..22596
                     /locus_tag="VXB71_000107"
     CDS             21625..22596
                     /locus_tag="VXB71_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0450288.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALKLLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPR
                     SIETTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILA
                     EIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKVCARF
                     SPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(22795..24684)
                     /locus_tag="VXB71_000108"
     CDS             complement(22795..24684)
                     /locus_tag="VXB71_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0450289.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNFFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            24822..26387
                     /locus_tag="VXB71_000109"
     CDS             24822..26387
                     /locus_tag="VXB71_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0450290.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            26387..27127
                     /locus_tag="VXB71_000110"
     CDS             26387..27127
                     /locus_tag="VXB71_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0450291.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(27236..27451)
                     /locus_tag="VXB71_000111"
     CDS             complement(27236..27451)
                     /locus_tag="VXB71_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450292.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(28322..29572)
                     /gene="ilvA"
                     /locus_tag="VXB71_000112"
     CDS             complement(28322..29572)
                     /gene="ilvA"
                     /locus_tag="VXB71_000112"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0450293.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(29622..29978)
                     /locus_tag="VXB71_000113"
     CDS             complement(29622..29978)
                     /locus_tag="VXB71_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0450294.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(30216..30452)
                     /locus_tag="VXB71_000114"
     CDS             complement(30216..30452)
                     /locus_tag="VXB71_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450295.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(30559..31581)
                     /gene="ilvC"
                     /locus_tag="VXB71_000115"
     CDS             complement(30559..31581)
                     /gene="ilvC"
                     /locus_tag="VXB71_000115"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0450296.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(31647..32123)
                     /gene="ilvN"
                     /locus_tag="VXB71_000116"
     CDS             complement(31647..32123)
                     /gene="ilvN"
                     /locus_tag="VXB71_000116"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0450297.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(32116..33816)
                     /locus_tag="VXB71_000117"
     CDS             complement(32116..33816)
                     /locus_tag="VXB71_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0450298.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(34016..35683)
                     /locus_tag="VXB71_000118"
     CDS             complement(34016..35683)
                     /locus_tag="VXB71_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0450299.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(35686..36051)
                     /locus_tag="VXB71_000119"
     CDS             complement(35686..36051)
                     /locus_tag="VXB71_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0450300.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(36208..36396)
                     /locus_tag="VXB71_000120"
     CDS             complement(36208..36396)
                     /locus_tag="VXB71_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0450301.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(36512..36997)
                     /locus_tag="VXB71_000121"
     CDS             complement(36512..36997)
                     /locus_tag="VXB71_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV0450302.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(37266..38810)
                     /locus_tag="VXB71_000122"
     CDS             complement(37266..38810)
                     /locus_tag="VXB71_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0450303.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            39023..39325
                     /gene="gatC"
                     /locus_tag="VXB71_000123"
     CDS             39023..39325
                     /gene="gatC"
                     /locus_tag="VXB71_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0450304.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            39325..40791
                     /gene="gatA"
                     /locus_tag="VXB71_000124"
     CDS             39325..40791
                     /gene="gatA"
                     /locus_tag="VXB71_000124"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0450305.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            40791..42233
                     /gene="gatB"
                     /locus_tag="VXB71_000125"
     CDS             40791..42233
                     /gene="gatB"
                     /locus_tag="VXB71_000125"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0450306.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            42362..42922
                     /gene="efp"
                     /locus_tag="VXB71_000126"
     CDS             42362..42922
                     /gene="efp"
                     /locus_tag="VXB71_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0450307.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            42944..43333
                     /locus_tag="VXB71_000127"
     CDS             42944..43333
                     /locus_tag="VXB71_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0450308.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            43326..43748
                     /gene="nusB"
                     /locus_tag="VXB71_000128"
     CDS             43326..43748
                     /gene="nusB"
                     /locus_tag="VXB71_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0450309.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     AVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(43797..44024)
                     /locus_tag="VXB71_000129"
     CDS             complement(43797..44024)
                     /locus_tag="VXB71_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0450310.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(44515..44700)
                     /gene="briC"
                     /locus_tag="VXB71_000130"
     CDS             complement(44515..44700)
                     /gene="briC"
                     /locus_tag="VXB71_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0450311.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(44859..45626)
                     /locus_tag="VXB71_000131"
     CDS             complement(44859..45626)
                     /locus_tag="VXB71_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0450312.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(45623..46489)
                     /locus_tag="VXB71_000132"
     CDS             complement(45623..46489)
                     /locus_tag="VXB71_000132"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0450313.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(46526..47893)
                     /gene="accC"
                     /locus_tag="VXB71_000133"
     CDS             complement(46526..47893)
                     /gene="accC"
                     /locus_tag="VXB71_000133"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0450314.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASRNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(47905..48327)
                     /gene="fabZ"
                     /locus_tag="VXB71_000134"
     CDS             complement(47905..48327)
                     /gene="fabZ"
                     /locus_tag="VXB71_000134"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0450315.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(48324..48809)
                     /locus_tag="VXB71_000135"
     CDS             complement(48324..48809)
                     /locus_tag="VXB71_000135"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0450316.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(48812..50047)
                     /gene="fabF"
                     /locus_tag="VXB71_000136"
     CDS             complement(48812..50047)
                     /gene="fabF"
                     /locus_tag="VXB71_000136"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0450317.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(50069..50800)
                     /gene="fabG"
                     /locus_tag="VXB71_000137"
     CDS             complement(50069..50800)
                     /gene="fabG"
                     /locus_tag="VXB71_000137"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0450318.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(50834..51754)
                     /gene="fabD"
                     /locus_tag="VXB71_000138"
     CDS             complement(50834..51754)
                     /gene="fabD"
                     /locus_tag="VXB71_000138"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0450319.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTSLLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTTHLAHVEDQASLVALLKK"
     gene            complement(51747..52721)
                     /gene="fabK"
                     /locus_tag="VXB71_000139"
     CDS             complement(51747..52721)
                     /gene="fabK"
                     /locus_tag="VXB71_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0450320.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(52840..53064)
                     /locus_tag="VXB71_000140"
     CDS             complement(52840..53064)
                     /locus_tag="VXB71_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0450321.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(53124..54098)
                     /locus_tag="VXB71_000141"
     CDS             complement(53124..54098)
                     /locus_tag="VXB71_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0450322.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(54098..54532)
                     /locus_tag="VXB71_000142"
     CDS             complement(54098..54532)
                     /locus_tag="VXB71_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0450323.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(54626..55411)
                     /locus_tag="VXB71_000143"
     CDS             complement(54626..55411)
                     /locus_tag="VXB71_000143"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0450324.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            55780..57144
                     /locus_tag="VXB71_000144"
     CDS             55780..57144
                     /locus_tag="VXB71_000144"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0450325.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            57147..57518
                     /locus_tag="VXB71_000145"
     CDS             57147..57518
                     /locus_tag="VXB71_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0450326.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            57732..59006
                     /gene="serS"
                     /locus_tag="VXB71_000146"
     CDS             57732..59006
                     /gene="serS"
                     /locus_tag="VXB71_000146"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0450327.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVEAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(59031..59930)
                     /locus_tag="VXB71_000147"
     CDS             complement(59031..59930)
                     /locus_tag="VXB71_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0450328.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(60040..60588)
                     /locus_tag="VXB71_000148"
     CDS             complement(60040..60588)
                     /locus_tag="VXB71_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0450329.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(60806..62128)
                     /locus_tag="VXB71_000149"
     CDS             complement(60806..62128)
                     /locus_tag="VXB71_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0450330.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(62219..62307)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(62471..64807)
                     /locus_tag="VXB71_000150"
     CDS             complement(62471..64807)
                     /locus_tag="VXB71_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0450331.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKGQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQIGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(64911..65459)
                     /locus_tag="VXB71_000151"
     CDS             complement(64911..65459)
                     /locus_tag="VXB71_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0450332.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(65456..65758)
                     /gene="zapA"
                     /locus_tag="VXB71_000152"
     CDS             complement(65456..65758)
                     /gene="zapA"
                     /locus_tag="VXB71_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0450333.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            65845..66726
                     /locus_tag="VXB71_000153"
     CDS             65845..66726
                     /locus_tag="VXB71_000153"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0450334.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            66730..67344
                     /gene="lepB"
                     /locus_tag="VXB71_000154"
     CDS             66730..67344
                     /gene="lepB"
                     /locus_tag="VXB71_000154"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0450335.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            67578..69944
                     /locus_tag="VXB71_000155"
     CDS             67578..69944
                     /locus_tag="VXB71_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0450336.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(69992..71275)
                     /locus_tag="VXB71_000156"
     CDS             complement(69992..71275)
                     /locus_tag="VXB71_000156"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0450337.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        21223 a        16054 c        13400 g        20806 t
ORIGIN      
        1 ataaattaat ttgactttcc ttatagagat gttcacatct tatttcaatt catgatacaa
       61 tccagttcct aaaactttgc tagaaattaa tttggctttc cgaattaatt tgttcagatt
      121 ttatttcatt tcaatatact gataaatcca ttcactagca cagggcaaga gggagtcgct
      181 attgatttca acggtagcag gtacatacag aggactccta cctcagatat actgcaatat
      241 catcgtatgc aaaaaacctc tgagattttt ctcaaaggtt ctgattttgc taattgctgt
      301 tctcaaccgc tgcagtaaca aaggcagtgt agagttcttc tggtcggttt ggacggcttg
      361 acagttcagg gtgatactga caagctacaa agaatttatt ttcaggaatt tccacgattt
      421 ctaccaaacg attgtctgga gaaactcctg aaaagacaaa acctgctgcc tcaaactgct
      481 cacggaaggc attattaaac tcataacggt gacggtgacg gcgttgcacc acttcttgat
      541 tgtgataagc agcagcagcc ttagagccac gtttcaactt agacggataa agtcccaaac
      601 gaagggttcc acccatatcc tcaatatcaa tctgatcacg catgatatca atgatagggt
      661 attttgtttc tggtgcaagc tctgcagaat tggcaccttc aagacctaaa acgtgacgag
      721 caaactcgat acatgtcaac tgcattccca agcagactcc caacattgga acatcatttt
      781 cacgcgcata gcggatggct tggattttcc cttctgtacc acgttgacca aaaccacctg
      841 gtacgatgat cccgtccgca tcagacaaga gttctgctac attctctgct gtcacatcat
      901 tggcattgac ccaattgatt ttaacttctg tatcattgac atagccagag tgtttcaagg
      961 cttcgaccac tgagatatag gcatcttgca actccacata cttaccaaca agggaaatct
     1021 taacttgttt cttgaggttc atgaccttgt ccaccatggc tgaccattct gtcatagccg
     1081 ctgctggtgc gtctaatttc aaatgatcac aaacaatttg gtccatccct tgtgcctgca
     1141 agttcagtgg aatttggtaa aggtgttcaa catccaacga ttcgataacg gcttctggtg
     1201 ccacatcaca gaactgggcc agtttatttt taattccttg accagctggc tcttctgtac
     1261 gaataaccaa catatttggt tggattccca agccacgcaa ttctttgaca gagtgttggg
     1321 ttggtttggt tttcatttca ccagcagcct tgaggtaagg aagcaaggtt gtatggatat
     1381 acatgacatt atccgcaccc acatctgcct tcatctgacg aagagcctct aggaatggca
     1441 aggactcgat atctcctact gttccaccaa cctctgtgat aatgacatca gagtcggtcg
     1501 ttagagcggc acgcttgatt ttttctttca aagcatctgt gatatgagga atgacttgaa
     1561 cagttgcccc aaggtattct ccacggcgtt ctttacgaag aacttcactg taaattttcc
     1621 cagttgtcac gttggaatat ttgttgagat tgatatcgat aaaacgttca tagtgaccca
     1681 agtccaaatc tgtctcagct ccgtcatctg tcacaaaaac ttccccgtgc tggtaaggac
     1741 tcatggttcc cggatcaata ttgatataag ggtcaaactt ttgaatggtt actttgagac
     1801 cacgattttt caagagacgg cctagactcg ctgccacaat ccctttccca atagacgata
     1861 ccacaccacc agttacaaaa atatatttcg tagacataga ttcctctttc taaaatgctc
     1921 aaggtcttgt taactacgag gggatataga aaacaagacc ctactaataa gaataatctg
     1981 ggacgactgc accagattca caactaatac tcttcgaaaa tctcttcaaa ccgcgtcaac
     2041 gtcgccttgc cgtagatatg tgttcctgac tttgtcagtc ttatctacaa cctcaaaaca
     2101 gtgttttgag cagcctacgg ctagtttcct agcttgctct ttgattttca ttgagtataa
     2161 aatacaagaa gataacttct tgaaaaaaca aaaatagctc cctaagaact agggagcccc
     2221 gacctctaaa agaggtgccc aaacaatatg atacctaaaa ataggataat tgtcaatagc
     2281 taactcttat tcctcgctgg tttcagcgtc gtcatctgaa aactcgtcgt cgtcttcgtt
     2341 gagatccaca tcttctccca agtcatctgg agcgatttcg ttgatttctg catcataagc
     2401 ttccacttca tttttttcat catctggatt ttcatcatcg tatgaaagag ctggatctgc
     2461 ttcgtatgca tcttcgtctt ctggatcatc tgcattgtag tcaatggcat ctgaatcacc
     2521 atccataaag gcattgacac gttttttctt agcttttggt gctacttcat cgtcgtcatt
     2581 ttcttcaaga gcgatgattt cttcgtcgat ttcgtccaca ccataccatg aacgaagacc
     2641 ccatttgttg tccccaagtg agatgaagct accgtcaaag ttcaactctg tgtagaacag
     2701 aggcaaagct tcgcggatat cgctgtttga tgttccaagg tagttttgaa tttcgtttac
     2761 aagatcgcta aaatgcatct catgatcgcg accacgaagt tctaatatag cacgcgctac
     2821 ctcaatcata gatagttcac ttttttcttg cccagcaaat acttctaatt ccaaagcgtt
     2881 tctcctcatt tatactacta tcgccagagc gaacagactc tgacctcatt ttatcattta
     2941 ctctttattt tacgataatt ttgcggaata gtcaaaggtt aagggggaga aagtggcagg
     3001 attagactaa ttccaatata aaactccttc ctttttctgt tgctccattt tccacaaatc
     3061 caagcgactt gaaacacctc ctagaagcat gattgtaggt gtagatttcc ttgactctca
     3121 attctttcca tccttttact cgagccaatt caatcaaagc acttagaatc ttttttccaa
     3181 gtcctcgatg ttggtaagcg gaattcccaa tcacaatggg gagattatcc tgagatagtg
     3241 taatatcccc aattggaaac cattctccct tctccttgac ttcaatccaa aaaagctcac
     3301 catgccgatc caaataggaa tacatggctt ccaaggtcgc ttgactgtaa ggaagcttca
     3361 ccccatctac gaggtaaacc aagttcacat cctgatacca agcaaaagct tcctcacaat
     3421 gattgacctt ataataagga acaaaacaca atgcactacc ttttcaacaa aagagttgct
     3481 gcttgattaa aaccatcaca ccagttatac cattttgctt catacccatc ttgagctagg
     3541 atacgatctt ctaaatcaaa aacagagtaa atctttcttt cctcgcaagc ttgcgcatag
     3601 agatgatata gttcatcacc accatctcta tcccactcag cagaaatcgt atcccgatct
     3661 gccaataaag tctgataagc cctgtgatgc ccatctgtaa tcagcaaaca atctccaaag
     3721 gcaagaatac tgattggatc gacttggatt gtttctgccg actggtaaag catctgaata
     3781 tcttgcaact tcttttctga taaatatagt tgagtcggat gaagatctgc tatgttgact
     3841 ttcatttctt tctcctcaag ggaattcgat actcacttct gtttgccttt aaatcgccat
     3901 tggaagcgga gcttgtcata gaagggaaac tcgataaaca ggactcccaa gcccacacag
     3961 agactggcaa ggacgtctga tgggtaatga actcccagat agactcttga taccagcaca
     4021 ctgactaggt agaggccaag gacgatttgt acgatttttc tccagactgg atctttaatc
     4081 cgctgactaa gaataacaat caaagtacct accatcaagg ttacagccag agaatgccca
     4141 cttgggaagg aaaatccctt ctcctccacc agatgtaaga tatctggccg tgggcgctgg
     4201 tagatatttt taaaggtcac gattaaaaga cctgccaaag ccagatttcc cagcatgaag
     4261 aaactttcta tcttccatcg cttacgataa aagacaaaag ctgtaatgac aacccaagtg
     4321 ataatcactg ggatatcaat cagacgtgtg agggctcgaa aaagaatagt caaataatct
     4381 ggtaagtctc ctcgaatggc agtctgaatc gattggtcaa aattgaccag cgtttcaggg
     4441 taaaatttga ccatgtagcc aagaataacg aaaagtaaaa gggcaaaact gcccttcatt
     4501 aaaaatgttt gtttatctct cataatgttt taaggttggt ttcaagagaa catacaacaa
     4561 ccagaatgaa acggaaaaga taacaccttc aatcaagtta aaaggtaata ccatggtcat
     4621 taggtagttg gaaagtccca aaatttttcc aatatcaaag ttagcaaact tagcgtacaa
     4681 aggaacagca taaacatagt tgagaaccaa catggccaag gttaaaccaa tagttccagc
     4741 tagagagcct agtaggaaac gaagggttgt ccgttccttt ttccaaatca aagcaaatac
     4801 gatgacaaaa actcccaaag ctacgatatt catcggcaaa ccaatgtaag tattcactcc
     4861 ttggctgtta agaagcaact tcaagagtga gcgaagcaag agcactccta gagcagcagg
     4921 caaatccatg accaccagac ccacaaggac tggcaagata ctaaattcga tcttgaggaa
     4981 agatgccgct ggtaaaagcg gaaaatcaaa gtacatcagc acaaatgaga tggctgatag
     5041 aattgcaatg gtcgaaagtc gacgtgtgtt tgtcataaca ggttcctcca attttctata
     5101 aaatcagaag aagttggaaa ggattcctct atctattctc actttttata tcccaaaagt
     5161 tccctcttac tctattaaag aaaaacaaag caagtggtta caatccggct ataaatctat
     5221 caaaacagac aaagctattc tttcgtcttc tcccatccag actatactgt cggttgtgga
     5281 atctcaccac atcagcttgc gctcgcggac ttctttaaag ggaaagaaat agagattttt
     5341 cttttagact aggcgacaag ctgtaggcat aacttctggt taggcaaagc ttgtcaacaa
     5401 agtataaaag gaaaagatca tttcctagtt aaagtcaccg ccggtcggga atcacaccct
     5461 gccctgaaga ctcttttatc ataacaaaaa acgcttgcaa gcgcaagcat tttgttcatt
     5521 ttcatttttt atttcaattt atccacttca taggtatgga cgagctcaag acctgcaaag
     5581 ttctgctggc gaagagcctc atagacaatc atgcagacgg tattagacac attgagactg
     5641 cggacatgtt catcattcat gggaatacgg agagccttct caggatgttc tcgcataaaa
     5701 tcttcaggta agcccttgtc ttcacgtcca aagagaaaat aatggtcctc gtcagtcgat
     5761 aaatccacct cagaatagat tttttccgcg aatttcgaaa tcagatagag ttttcccttc
     5821 atctgagata tgaaatcttc taaactctcg taaaaataaa tctctagctt atcccagtaa
     5881 tccaatccag cccgcttcat cttgcggtca tcaataggaa agcccatagg cttgatgatg
     5941 tggaggggag aattggtcgc agcgcaagta cgcgcgatat tgcctgtatt ttgtggaatt
     6001 tgaggttcaa ataatacaat gtgatttgtc atgacttgct tcctttcacc attgcaaaaa
     6061 aatagccaca ctgcccggag tcaagctcag caaacagcgt ggttaaggca tcgttaactt
     6121 acctcacaac aggtttgaag taaatcagcg aaactacttt cttagtataa cactttcaga
     6181 atcattgtca atagaaatga cttgattttt tcaatttttt caagctattt ccaagggttg
     6241 taaaatcgtc cctgattctg caagataagt agtaaactaa ctactaaaaa caaggttgcc
     6301 aagagcaagg taatatagtc tccttttttc aaggcctgat aactatacca tgtgcgtttt
     6361 ttctctttcc caaagcggcg aagctccatg gcagtcgcaa tggtatcaat gcgttctagc
     6421 gagctaaaaa tcaagggcgt aataatgagc agattgcctt tgattcgttg cataagagaa
     6481 gctttcttgg ataattccat cccacgcgcc tcctgagaca tcttgatagt aaagaattct
     6541 tcctgcaaat ctggaatata gcgcaaggtc aggctgacag aataagcaat cttatagggc
     6601 acaccaattt gatttaaact ggaagcaaac tgactaggat gggttgtcat caaaaagata
     6661 atagccagag gaatggtgca aagatactta atggccaaat ttagcagata aaagagctcc
     6721 tggctggtta gagtgtagac accgattccc tgccaaatca cacttctctc tccataaagt
     6781 ccaaccccat actcgggaga aaagagatag accatcaaaa cgtttaaaac ggcaaatacc
     6841 gtcgcaaaaa cggctacaaa ggaaacatct ttaaagcgaa tttctgataa atagaggaga
     6901 aagactgaaa agatggcaat cagcaagagc attctggtat catagctaat catggccgcc
     6961 aatgatacca gaatgaaaaa gagaagtttc ccagctcctg acaagcgatg aatcacagta
     7021 tctctatgct ggtaaccgat taatttagct tgcatccctc tctcctttct ttgtaaaatg
     7081 ccgttaaatc cagtggatcc acatctagtt tcttagccaa gttaaagatg gaggtttctt
     7141 ttagattggc ttttactaac agctcaggat cgctcaacag actggctgga acagtatcgg
     7201 caatcaattc tccatccacc atgacaagga cccggtctga ataatccagc atcaattgca
     7261 tatcatgggt aatcatgaca atggtatgcc ctttttgatg taactcttcg agaaattcca
     7321 taatctcagt atagttcttc tgatcttgac ctgcagtcgg ttcatctagg agaataattt
     7381 cagctcctaa gaccaaaatt gaagcaatgg tgacacgttt tttctgacca aatgacaggg
     7441 cagaaatagg ccaattacgg aattcataaa gtccacagat tttcaaggtt tcatagactc
     7501 tcgtttcaat ttccttctca tccacacctc gcaaacggag ccctagagcc acctcatcaa
     7561 aaatcatatt ggttgaaatc atttgattag gattttgtag cacatagcct actcgttccg
     7621 cccgctctgc aacagaatcg ccttttatat cctgtttttc ccaaagatag cgtccttccg
     7681 tctgaataaa gctacttata gccttggcta gagttgattt ccctgctcca ttttttccga
     7741 caatagcaat cttttcaccc tttttaatat ctaaatgtag ggattttaaa atcggtctat
     7801 catcataaga gaaagacacg tcctctaatt taaagagtga ctgcaattct ggagtttctt
     7861 ttgccagttc attctgcagc tgaacctgac cttttgagat agacatgtta tccagattcg
     7921 ctaactgttc ttccttgact aagtccacac ctaattgacg gagagtcgtt agataaaggg
     7981 gttctcgaat tccattttga gtcaataaat cagtcgcaag caactggtca gggctcccat
     8041 taaaaaggat acgaccatcg cttatcaaga caatccgatc cacagggcga tgcagaacat
     8101 cctccaaacg gtgctcgata atcagagtcg tcgtcccctc ttccttatga atctggtcaa
     8161 tcaattcgat aatatcctga cctgacttgg gatctagatt ggcgagtggc tcatcaaaca
     8221 agagaatcgg actttcatca atcaagacac cagccagact gactcgctgc ttttgtccac
     8281 ctgacaaatc ctgaggacgc tgatccagta aaggaagaag gtccagcttt tcagcccatt
     8341 tataaacacg acctttcatc tcatctaggg ctgtcacatc attttccaga gcaaacgcca
     8401 aatcttctgc cacagacaag ccaataaact gcccatctgt atcctgcaaa actgtgctaa
     8461 ccagatgaga cttatcatag atgctcatat caaaggctac ttgacccttt atcaaaaatt
     8521 ctccatatgt ctgacccttg taaatattgg gaataatccc attcaaacac tgacccaagg
     8581 tagatttacc tgacccagat ggtccaacaa ttaagacttt ctctcccttg taaatggtca
     8641 agtctatccc ttgcaaggtc ggttcttgtt gtgtttcata ccggaaagag aaatccttcc
     8701 actcaattat agcttctttc atcttactct cttcattcgc ttcttagact tctattttat
     8761 cataaatcaa gcccttcttg cagtctcttc tcttaaaatc ttagcgccaa aaagattcct
     8821 atcctagctt acttgcctaa ctaatctata aacatcgaaa aagactagtt gcccagcctt
     8881 ccccatcatt ttatactctt cgaaaatctc ttcaaaccac gtcagcttcg ccttgccgta
     8941 ggtatggtta ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
     9001 ttcgtcagtt ctatccacaa tctcaaaaca ctgttttgag caacctgcgg ctaacttcct
     9061 agtttgctct ttgattttca ttgagtatta gtcctttttc aaacttcctg cacgagtttg
     9121 ggttcctgca taggcaagta agagaagagt tcctgcaata gctacagata caccattggc
     9181 aattcccgca acaatccctt gtgcaaatac tttttctgcc gcttcttgat aaatcacaac
     9241 atctccaagt ggtgccaaga caccccaaac aagggcattt gcaagtagtt gaatgaggtt
     9301 aaaaataaga atatctttcc agtcaaaaac accattgatc actcgaacgt actttctaaa
     9361 aagtcccaca actagaccaa agagtccgct agcgataatc caagtccacc atagaccata
     9421 accagcaaga gagtccttga ttgcatgacc aatcaacccg acaagcaaac cgataatcgg
     9481 tccaaaaata atagaaagta gcgcttgtac cgcatactga agctggatgc ttgtatttgg
     9541 aacaggggtt ggaatgttga tcatcccgat gacgacaaag agggcagcgc caattccgac
     9601 agcaacaact tgtttaattg taaatttgat ttccatacta ttctcctatt ttatccttct
     9661 attttcttta tttcaatggt ccaagatgaa ccgacaccta cattataggc cttggcaaag
     9721 gaaccttggt tgatagccaa acctaaacga tagagagagt tgatgtaaag gatgggttgc
     9781 ccaattctca catctgcaaa tgatttgcca tagacaacct gattttgata gaccagcata
     9841 tcagcatgat agatggtcac ttcaaaacga tcaccaaatt ctggttccag cttgtaaaat
     9901 tcttcccgtg tgatagaggt ccaaagcgaa ccgaaacgca catccagaat atcaatggct
     9961 cccttcacca gatgatcttc tatgatggtc gctacgactg gaagctctac aatctgttcc
    10021 acactgagct ctggccctac ttcctcaaaa gtaatgtgac cactggccag tttagcacca
    10081 gtataggcat agacatcacg accgtggaag gtataagaat gctctgtgtt ttgacgccta
    10141 ttggccacct cagaaatctc acgaatggct acaatgccaa cgtgtttctt gataaaggaa
    10201 agcgtcccat tatctggcgt gacaatgtat tgattttttg cagtcttggc aactacactc
    10261 ttacgtttcg aaccgacacc tggatcgaca accgatacaa acgtcgttcc ctcaggccag
    10321 taatccaccg tctgaaagag acgatagctc ccctcaaaaa tattataagg cgtgatatcg
    10381 tgcgtcaagt gatggatttt taaggttgga gactcttcta aagccactcc aatcatagcc
    10441 gacaccgcac catcaaccag accaaagtct gattgtaata ccagtaaatt attgttcatt
    10501 ttatctcctt gtatatcctt tatcatacca tatttcagag aaagtcgcta atagctattt
    10561 caattggtta gggtatagtt ttaccttata gcgaattttc actaaaagct cttgttatta
    10621 gctagtaggt gcattttttc ttgaaaaagg gtatgatagt tacatcatga aaaagtaggt
    10681 tttattatga aaattatcct tgtcggaggg ggaaaagttg gttttgccct ctgtcgctcc
    10741 ttggttgcag aaaagcatga tgttttgctg attgagcaag acgaagctgt tctcaatcat
    10801 attgtcagtc gctttgatat cattggtatc cttggtaacg gggccgattt tgccattctt
    10861 gagcaagcca gcgtccaaga ttgtgatatc tttatcgccc tgactgagca cgatgaagtc
    10921 aacatgattg cagcagttct agccaagaaa atgggagcta aagaaactat cgttcgggtg
    10981 cggaaccctg aatattctaa ctcttatttc aaggaaaaga atattctcgg tttttctctt
    11041 atcgttaatc ctgagctctt ggctgcccgc gctatcgcga atatcattga cttccccaac
    11101 gccctgtctg tcgaacgctt tgctggtgga cgcgttagcc tcatggaatt tgtcgtcaag
    11161 tccaccagcg gtctttgcca aatgcccatt tctgattttc gtaaaaaatt tggtaatgtc
    11221 attgtctgtg cgatagagag ggatcatcaa attatcattc caagcggtga catgactgta
    11281 caggataaag atagaatctt tgtcactggt aaccgtgtcg atatgatact cttccataat
    11341 tattttaaat cacgcgccgt gaagagcctt ctcatcgttg gagcaggtag aattgcctat
    11401 tatctacttg gtattctcaa agatagtcgt atcgatacaa aagtcattga aatcaatcct
    11461 gaaatcgcca gcttctttag cgagaaattc ccaaatctct acatcgttca aggagatgga
    11521 accgcaaaag atatcctgct ggaagaaagt gctcaacact atgatgccgt tgcgactcta
    11581 acaggagtcg atgaggaaaa tctgattaca tctatgttcc ttgacagggt aggtgtacag
    11641 aaaaatatta ctaaggtcaa tcgtaccagt ctcctcgaga ttatcaatgc gcctgatttt
    11701 tcaagtatca tcacacctaa aagcatcgct gtagatacga ttatgcactt tattcgtggt
    11761 cgagttaatg cccagtattc agaccttcaa gccatgcacc atctagccaa tggccaaatc
    11821 gaaaccctgc aattccatat caaggaagcc aataaaatga ctgccaaacc tctttctcaa
    11881 ctgaaattga aaaaaggggt tcttattgca gccattattc gaaagggcaa gactattttc
    11941 ccaactgggg aggatatgtt ggaagttgga gacaagctcc tagtaacaac cttgttgcca
    12001 aacatcacca agatttatga cttgattgcg aggtaagaaa tgaataaaag tatgattcgt
    12061 tacctccttt caaagttact tttgattgaa gctgttctcc tcttggttcc tgtggctatc
    12121 gctgtctatt accgtgaatc gagccaagtc tttacagccc tcttttcgac catagggatt
    12181 ctcgtattgt taggcggttc agggagttta cagaagccaa aaaatcaacg gatttatgcc
    12241 aaggagggag tcttgatcgt tgccctctgt tggatccttt ggtctttctt tggtggtctc
    12301 ccctttgtct tttctgggca aatccctagc cttattgatg ccttttttga aattagttct
    12361 gggtttacaa ctactggagc aagtattttg aacgacattt cggttctcag ccgttccctc
    12421 ctcttctggc gaagttttac ccacttgatt ggagggatgg gagtgcttgt ttttgcactt
    12481 gctattatgg acaatgccaa aaatagtcac ctagaagtaa tgaaggctga ggttcctggt
    12541 cctgtctttg gtaaggttgt atccaaatta aaaaacactg cccagatcct ctatctcctt
    12601 tacatagccc tcttttccct ctttgtcatc atctattatc tagccggtat gcctctctac
    12661 gatagttttg tcattgctat ggggacagcg ggaactggag gatttaccgt ctataacgat
    12721 ggaattgccc actatggtag ctcactgatt acctatctgg ttagtatagg agttttggtt
    12781 tttggggtaa atttcaatct ctactactac cttatgctcc gtcgggttaa ggccttcttt
    12841 ggagatgaag agcttcgggc ttacttggtc atcgtgctgg tttctacagg cttgattagc
    12901 ctcaatactc tctacctcta cccagggttt tcaaagagct ttgaaatgac cttcttccag
    12961 gtttccaaca tcattacaac aactggtttt ggatatggag atattaccaa ctggcccctc
    13021 ttctcccagt ttatcctcct tttcctcatg gcaatcggtg gctctgctgg atcaactgca
    13081 ggtggactca agattattcg aggcctcatc ctttcaaaaa ttgccaaaaa ccaaattttg
    13141 tcaatcctat cgccccaccg tgttttgacc ctccatgtta ataaaatggt gattgacaaa
    13201 gatacccagc ataagattct caagtacttt gtcatctatg ctatgatttt gctagcgctt
    13261 atctttattg tcagcctaga tagcaatgat tttctggtcg tgaccagcgc tgtctttagc
    13321 tgtttcaata atatcgggcc tattctagga accacttcta gtttctcaat ctttagtccc
    13381 atctcaaaaa ttctcctctc ctttgcaatg attgcagggc gcttggagat ttacccaatc
    13441 ctccttctct ttatgaaaag aacttggtct aagagataaa atacaaaatc cctcttttta
    13501 caattgtgaa agagggattt ttatattaaa aagggggaac gtttttaaat ccaagcctgt
    13561 ctgtaagcaa agttcttact caaataaaag atggaaaaac ttactacaca gcttggtaat
    13621 gctccaatac aaattgtaag gctttacttg gattctttgt taaatgaata tattccattc
    13681 ctctggtagc aactatctga atacctaatc tttctgcatc caccttcatc tctctataat
    13741 aactccgaac ttgtggagcc agaataatta aatcataaac acccataata tcataatgag
    13801 ctccgtacgc tcctgaattc gcaatcactc taacttctgc taattgagcg ccctcgttaa
    13861 ttgcattggc taattacgca cttgttccag accctgcaca aagaaccagt actttcaact
    13921 ccttactttt tattacatct atctcaccag gcattatttc acttgtatcc tcctctaaaa
    13981 taatatcatt tgagcttgca atatctacaa cctgtagtag atatctcgta tttagacaat
    14041 atgaaaacaa gacgacttcc atataggaaa ccgccttctc tctatgttga gtgatttata
    14101 ttaaaataac ttttcttcta gctgcatttt attattataa aaacattcat cataaccctg
    14161 aacttaaata acgattttta ttcaagatac atactcctag aataaacttt atatgaaatt
    14221 ctcatttttg tttttacaat tctccttagt taaatcttgt ttaatatatg ttttacatat
    14281 agtatttagc gccacatagt actgaactct ctccaaaaac ggttattcct ctttgaatag
    14341 ggcgttatca caagaaaagc atctccacgt ttcaacttca tatggctcaa aaacaatcaa
    14401 ttgatgctaa aacctgtacc tagatgtttc ggttcataaa accatgaaac tgtaaaagtg
    14461 aatgaaattg atagcgatag tcaaatcaag aggcatcata actctaaaaa gtcacaatat
    14521 ataagttcat cctcggaaaa atatcattct aattgttgaa atgcctacat gaaaagaaac
    14581 gtcaaatgct catgaaacaa cgaatacagg tatcaaaact atgacaaaac aagtccctaa
    14641 atttactaaa gacactgctc aactttacac ctgtaagtgg ttgttgtata ataaagttac
    14701 aaagatgtac gaccacactg ttgtaaatca tagtgttcgc gaatatatta ctgatagcat
    14761 ttctacaaat acaattgaag agactggata gactttaaac gaaatatgtc agtgttttgg
    14821 cattcctagc cttcatatca tttaaagaat tctatagaca aaatttttcc caatacagac
    14881 actcgtaaca actgcttcat ttttctacca acatatttag gaacaggata agatacaaga
    14941 ggattaatcc atagatcagt tctataccaa tctaagacaa ataagctaaa aaaacgattg
    15001 ataataagca aatagattcc aaattttctc tatctgctca ttttaataaa caatactagt
    15061 gtaactatcc ttccagtcag aaacttgtca aatcacaccg aaaactcttc taaaatttat
    15121 ctcgttaggc aatcaagcaa aaactcgacg atagtacaaa cattatcata cagaattgac
    15181 tgcctaaatt atatacttta gtaaggtttt cggataagaa aaaaggttca ttttacattt
    15241 ctaaacattc ttttctaaga tgaaaaacag aatttttcga ttgtgattta aagcaacaag
    15301 aagattttca gtatcatcct atagatacga gctaattaag aaaaactaca tttttgaata
    15361 taaactacaa taatataaac taaattttat aggaggaaga caatggattg gtacgattat
    15421 atgatacagg catccaaaca atcacaattc aacgcaagcc attggtttcg ctatttgcga
    15481 aaagttattt ttgaagacta ttcttattta acaaaccaag atgtagaaaa gttgctagac
    15541 tccaaagaac taacccgttt tcaaaaaatt agcttgaagt atgcctttca agagcatact
    15601 ccaactcata aatatgtgat ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa
    15661 ttgatggaga aatacaaaca tggataaaat gaaaccggtc ttccaagccc taaataagaa
    15721 attaattcag gaaaatctga ctttaacaat tatggttatg tcttagaata tcatggttta
    15781 cgtaccacac aagatgttga tgctttttat gaccaaaatc agaaaatcaa tgaaattatt
    15841 gctcgtgtag gaaaacagtt taatcttaac atccacgaag agttatggct caacaatcat
    15901 gttgcaaagc aaatatgaac aaacaacctc ccttaagttt atgcgaatcc ttgtactcat
    15961 ttgagaatct gaccgtttta gtagtcccta ttgagtatgt gttaggaatg aagatgatga
    16021 gtatcagaga gcaggatttg caagatattg gtgcaattat taaatacaaa aactttcatt
    16081 caccattcga tacctttaaa tatttaaaag acatgggatt tgatactatt gacctctctg
    16141 ttctattaga aggttttagt tatgcttatg gtatggattg gttagaaaaa ttttttaaag
    16201 aaaatcaaga taaacttcgc gaattttatt aacagtatca aacaagatga ttgtcaatta
    16261 gccagtcatc ttatttttat gatgaaatga aataaaatcg gaacaaatca cttagagaat
    16321 tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa atgaaataag
    16381 aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta gaagtaaagg
    16441 tgtactattc tagtttcaat ctattatatt tcagattcgg tccactattc cttcccaaaa
    16501 acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa ccctcagtcg
    16561 tttgaccgag ggttcctttt cattattcaa aaacttgatt agctcaatgc atccaaggca
    16621 tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt ttgttctgga
    16681 gtgaggtatt tagtatttac acagtatcca gagatacgta cgataacgtc ttcacctgac
    16741 ataatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg ttgtccaccg
    16801 ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc acgagtctta
    16861 ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc ataactaaag
    16921 tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt gttagatggg
    16981 ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc ttcgttgagg
    17041 tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac gttagatgtg
    17101 attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct acgtagacga
    17161 gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc atcttcaccc
    17221 cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc gtcacggatt
    17281 ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc aaatccacag
    17341 ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg aacagcttcg
    17401 tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta agtgtcagtc
    17461 aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag aacttcgtca
    17521 cggattggtt cgatatcaaa tactttgtag tctttgtgaa catcgtcgta accaccattc
    17581 aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg gatgttgtgg
    17641 cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca gctcatttca
    17701 ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga gtgtttgtgg
    17761 ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca aagaactgtc
    17821 aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg gtagtccatc
    17881 ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt gataaaggtt
    17941 gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac tgtacgaagt
    18001 ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt accacgagca
    18061 aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga tgtagcagca
    18121 ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat tgcttctttc
    18181 acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg aacaacttgt
    18241 tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc ttcatcgatt
    18301 tctttgattg cattccagtc atttactttt tcttgcatca agtagtctgc accgtaaaga
    18361 gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg aagaccagtt
    18421 acagtgtgtg cgtgacgagc gcgacgaata tttgaagtgt aggcacggaa aataccgtcg
    18481 ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg ttcgtatcca
    18541 ttttctttca aagtagtttc agccatacgg ataccacctt ttggcatgaa gttcaatttg
    18601 aagagttcat cgttttggat accgaagata acttcatttt ctttgtcgat aaatccagca
    18661 gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc ttcgtagtgt
    18721 gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg tcctgcaagg
    18781 aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga tacacttgct
    18841 ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat atcttgtgct
    18901 tcaacaactg tcttaacaac catattaatg tcctcttttt tctagtaaca gtcatctgtt
    18961 acattcatga gacaagtata ccatatagta accgatttta acaagtgaaa aatccctatt
    19021 tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta tatttttgaa
    19081 aaaataaagt ccttttttct ttttttcaga aaaaagggta taataaaaga aaataagcag
    19141 taacactcaa tggaaatcga aaagcaaact aggaagctag ccgcaggctg ctcaaagcac
    19201 tgctttgagg ttgtaaatag aactgacgaa gtcagctcaa aatactgttt tgaggttgca
    19261 gatggaagct gacgtggttt gaagagattt tcgaaaagta taaaaaggtg ctaggcatgt
    19321 tgatttttcc tttgctaaat gatttgtcaa gaaaaatcat ccatattgac atggatgcct
    19381 tttttgctgc ggtggaaatc aaggataatc ctaaactcag aggaaaacct gtcattattg
    19441 gaagcgaccc tcggcaaaca ggtggacggg gagtcgtttc tacctgtagc tatgaggctc
    19501 gagcttttgg tgtccattct gccatgagtt ccaaggaagc ttatgaacgt tgtccccagg
    19561 ccgtctttat ctcaggaaat tatgagaaat acaaagctgt gggactccag attcgagcta
    19621 tttttaagcg ctatacagat ttgattgaac ccatgagcat tgacgaagcc tatttggatg
    19681 tgacagaaaa taaactcggt atcaagtcag cggtcaaaat tgctcgcctc attcaaaaag
    19741 atatctggca agaactccat ctaactgctt ctgccggtat ttcctataac aagttcttag
    19801 ctaaaatggc gagtgattat caaaaaccac atggtttgac agtgattcta cctgaacagg
    19861 ctgaggattt tctcaaacaa atggatattt ccaaatttca tggagtagga aaaaagacag
    19921 tagaacgtct tcatcaaatg ggcgttttta ctggtgctga tttacttgaa gttcctgagg
    19981 taaccctaat agaccgtttt ggtagactag gctatgatct gtatcgaaag gctcgtggca
    20041 ttcacaactc tccagtcaaa tccaatcgca tccgtaaatc aatcggcaag gagaaaacct
    20101 acgggaagat tctccttgct gaggaagata tcaaaaaaga gctgactctt ctatcagaaa
    20161 aagtcgctct caatctacat caacaagaaa aagctggaaa aattgtcatt ttgaaaatcc
    20221 gctacgagga cttttcaact cttaccaaac gaaaaagtct tgctcaaaaa acacaagatg
    20281 ctagtcagat aagccaaata gccctgcaac tctatgaaga attaagcaag aaagaaagag
    20341 gtgtccgcct attggggatt accatgactg gattttaaag ctcaatgaaa atcaaagagc
    20401 aaactaggag gctagccgca ggctgctcaa aacactgttt tgaggttgca gataaagctg
    20461 acgcggtttg aagagatttt cgaagagtat aaaaccttga agagttgccc cttcaaggtt
    20521 tttcttatac aaataaacgg acaaaactgt aaagtagcaa aacactacca agcacgatac
    20581 ggtatttacc aaaaagggtg aagtcgtgtt ttttcacata gctggtcaag aagcgaatag
    20641 ccaccatgct gaccgcaaaa gctactccca tcgcgaccaa gagcaaaaac aattgcccaa
    20701 agctcaagag ttctccggct ttcacaaatt tgaaaatctt taaggcacta gctccaaaca
    20761 taacaggaat cccaagatag aaggtaaatt ctgtcacaac tgaacgactg gttccattta
    20821 acaaaccacc gacaatcgtt gcacctgaac ggctagtccc tggtaaaaga gcaagaactt
    20881 ggaagagtcc gatatagaaa gcggtcgtat aaggaagctt gtccaactct gttacacttg
    20941 gctcgatagc acgcgcttta ttgcgctttt ccaaatagat gaaggcaacc ccgtagataa
    21001 tcaacatgag agcaactgaa accatgttat ggaagtgggt atcaaaccaa tcatcaaatt
    21061 taaagacacc aagtaaaggt aaagtagcaa tcaagacctt caaccatagt ctccaagtct
    21121 tacgaacttc ctgtttgtcc ttagtcggtt taaaaggatt gagcttgtta aaataaatca
    21181 ccataactgc taaaatagca ccaagctgaa tcacgacatt aaacatggac ataaaggctt
    21241 cattttgatt ttggtattgg atgaattcct ctgctaaaat caagtgacct gtactggaaa
    21301 tcggcaacca ttccgtaatt ccttcaacaa tcccgaagaa gatagatttt aaaatttcaa
    21361 taagatacat agattactcc ctatattata attagcgcag ttagctactg ccaaagccca
    21421 agtggtatac ttggaataag ccactgtgga ttagttcatt tcctccaatc gcttgacgat
    21481 ttccgaaagg atctaaccac agcttttgtt tcaattggta atgagtttga taacgcatag
    21541 acgttttatc tcgtctaagg taacaaggca aaaagttcgt ggataaccaa gtagacttga
    21601 aatactatat ctggaggtac tcccatgctt tatgtgggca ttgatatcgc taaaaataaa
    21661 cacgatgtta cagccttgaa tgttccagga aaaactgttc ttaaaccact cactttttca
    21721 aataataaag ctggttttga actcttagat ctgtctcttc gacagctcaa ccaagactgt
    21781 ctcatcgctc ttaaacttct ttctgatccc aatcgtgaac aatttcaaca cgataatcgg
    21841 caagtagacc taaaaatact ggctagacat attcatcgtc tcaagaaaaa acagtctgat
    21901 tggaaagtac aatacactcg ttgtcttgat atcatctttc ctgagttgga taaaatcgtt
    21961 ggaaagcatt cagaatatac ctaccaactc ttgacgcgct accctaatcc tcagaaaagg
    22021 attgaggcag gatttgataa gctgatagaa attaagcgat tgaccgcttc taaaattcag
    22081 gatatcctct cagtcgcacc tcgttctatc gaaacaacat ctcctgctcg tgaattcgaa
    22141 atcatcgaaa tcatcaaaca ttacaagagg ctcattgaca aggcggaaac atgtgtcaat
    22201 gacttgatgg ctgagttcaa ctcagtcatc acgacggtta ctgggattgg gggtcgttta
    22261 ggggcggtca ttttagccga gattcgaaat attcatgcct ttgataatcc tgctcaatta
    22321 caagctttcg ctggactgga ttcttctatt tatcagtcag gtcagattga tttagctgga
    22381 agaatgatca aacggggttc ccctcatctg cggtgggcac tcatacaagc tgccaaagta
    22441 tgcgctcgct tttcacctgc ttttaaggcc tatcttaaga ctaagttaga acaaggaaaa
    22501 cattacaatg tagccatcat ccaccttgca aaaaaactta tccgaaccct gttttatatc
    22561 ctaaaaaaga gctgccattt gacgaacaaa aagtgatgta atttctgaaa ttaacacagg
    22621 attacctttg aaaaaatgga ctttttcaag ggctttttgc cgtgctctaa aatcatcgcc
    22681 aaatcatcaa attgaaataa gaaatagttt agataaaact attgactttt cttatagttt
    22741 gtctttcttc tatcttccat tatatcatac tttttcagtc tatggtagct ctctttaaaa
    22801 ggctccgata ctgccgccac ctccgcctcc agagaagcca ccgccagaac ttccacttcc
    22861 agaagatacg gagtaggtac ttgctgtatt tgcgacacta gcataatggc tcatttgcgc
    22921 gcttgaatga taaaacatac tgtgccagcc ataagctaca tagagattga tatctggatt
    22981 ttcaacttga atctgatgaa ccttcatcaa atgactaacc ttgtccgcat agccaaataa
    23041 ggttgcatag accaagagac gattccaaac aacaatactt tccaattcag ccttatccag
    23101 tcgtgcaatc tcacgtaaca tattttcaaa actggtccag agatagtaga cctcagctcc
    23161 cgcttcattt agaacaccat cacgattatc tagtcgaagc ttccaataat agaaaacaga
    23221 caaaactaac cctagaaaac caagtattgg caaagggagg taaagatagc catgaacgtc
    23281 taaactgtac aagaacaaac caaatccgat aaataggggc aagatagtca agacacccat
    23341 acccacttgc aaagtctttt ccaaaccagt taaaggacga tagtaatctg ggagccccca
    23401 gaaggaaact cgttttctca ctccttcttg catctggttc aatacctctt caaaagaaga
    23461 tttgagttga agccctcttg cttgaatccg tttttcatca gaaactttgg ctctacgata
    23521 aagactatca gataccttgt aatccgcaaa aaaattggaa agagtggctt cttttttgcc
    23581 tgaaaaggct agatttagac agtctctctc aaatcttgac aaaccatctt ctttcaccaa
    23641 tctcaagcca actgcatctc cttctgaaat aatagagaca ttcccacggt ctatcacatc
    23701 tagcaaggta gcttgaataa gttggtcaaa agtgaatttg ccagccccct tgaccaaggg
    23761 actcacttcc tccaaggagg tcgagtagac tgcttctgat aaaaccatag gctctaattc
    23821 cattggtggt tcatagagac gatgattttt ggcatatttg actgaaggag tggtctttct
    23881 tctataaata aaatagaagc agacactcaa taacaaggag atagaaagta tcgaagggag
    23941 gacccaagta acgagttgtt tactctgatc tttttctcta acaatcgagt cttctatctt
    24001 attaaactct tctaaacgat tccctttcaa gccctgatcc ctagcgctag caaaatcggt
    24061 ccgagaccaa taggcatgca actcaactcc acgcttagcc ggaagattgt ctaaacggat
    24121 agtataatca aggttactct tttcaatcgt tccctctcta aaaagtttcc ctgtatggaa
    24181 aaagagtttc tcagccccct tgtctcccct tacatgaaat tcaaactttt caatagactc
    24241 tgaactatct gtcagaggtt gccaatttaa ttcagcgata tcatcataaa ggaaaagtaa
    24301 attttttaag ttccagacga ggtcaacttc aactatgtcg ccctcctgac ctggattata
    24361 gactctcaca gtataaccat ccgcttcttc tgttacttcg ctagtcacat ctgctagttc
    24421 tgcaccgttt ttcgcagcct gaacctttgg atgagggtca atgtcaaacc cgctaggcat
    24481 cttaccagca cgtccaagtc ccacgatttg gcccttaaag tcctcctcaa actggtaaac
    24541 tatcttctgt ctaaactctg ccgtattatc tgcatgaata tacaaatccc cttgataaga
    24601 gtttatcttg aaatcaatgg caaaaacaga gagtggaaga aggcaaaaca agcctaacac
    24661 cagtaagaaa aaagtttttt tcatcaacta agcccccttt ttatctttct tatcattata
    24721 gcatcttttc gtaagtaaag gcttacttat gttgaaaaat tacgcatttt tcgataaaat
    24781 aggagacagt tattttttaa tagatcagaa taggagaaat catgagaaaa atatacctat
    24841 ctattttcac aagtctcttg ctgatgctag gacttgtcaa tgttgctcaa gccgatgaat
    24901 atttacgcat cgggatggaa gcagcatatg ctccctttaa ctggacccag gatgatgata
    24961 gcaacggagc tgtcaaaatc gatgggacca atcagtatgc caacggatac gatgttcaaa
    25021 tcgccaagaa aatcgctaag gacttaggta aagaaccttt ggttgttaaa accaagtggg
    25081 aaggtctagt ccctgccctt acttctggta agattgacat gattatcgca ggtatgagtc
    25141 caactgcaga acgcaaacaa gaaattgcct tttcgagcag ttactacact agcgaaccag
    25201 ttttgcttgt caaaaaagat tctgcctacg caagtgctaa atctttggat gactttaatg
    25261 gtgcgaaaat cacttctcaa caaggtgtct acctctacga cttgattgca caaatcccag
    25321 gtgctaaaaa agaaacagcc atgggagact tcgctcaaat gcgccaagct cttgaggctg
    25381 gtgtcattga tgcttatgtt tctgaacgtc cagaagcact gactgctgaa gctgcgaact
    25441 ctaagttcaa gatgattcaa gtagaacctg gtttcaaaac tggggaagaa gatacagcta
    25501 tcgctatcgg gcttcgtaaa aatgacaatc gtattagcca aatcaatgcc agcattgaaa
    25561 ccatttcaaa agatgaccaa gttgccttga tggatcgtat gatcaaggaa caacctgccg
    25621 aagctacaac aactgaagag actagcagta gtttctttag ccaagtcgct aaaattcttt
    25681 ctgaaaactg gcaacaactc ttgcgtggtg ctggtatcac tcttttaatc tctatcgtcg
    25741 gaaccatcat aggtctcatt attggacttg ccattggtgt cttccgtact gctcctctct
    25801 ctgaaaacaa agccatttat ggccttcaaa aactagtcgg ctgggttctc aatgtctaca
    25861 ttgaaatttt ccgtggtacg ccaatgattg ttcaatcgat ggttatctac tatggaactg
    25921 cccaagcttt cgggatcaac cttgaccgta cactggctgc tatcttcatc gtttcaatca
    25981 ataccggtgc ctacatgact gaaatcgtcc gtggtggtat cctagcagtt gacaagggac
    26041 aatttgaagc tgcgactgct cttggtatga cccataacca gaccatgcgt aagattgtcc
    26101 tacctcaggt agtccgtaac atcctacctg caactggtaa tgaatttgtc atcaatatca
    26161 aagatacatc tgtattgaac gttatctctg ttgtcgaact ttatttctca ggaaataccg
    26221 tggcaacaca aacctatcaa tacttccaga catttacaat catcgccgtg atttactttg
    26281 tcctcacctt caccgtaaca cgtatcctac gatttatcga gcgccgaatg gacatggata
    26341 cctatactac aggtgctaac caaatgcaaa cggaggattt gaaataatga cacaagcaat
    26401 ccttgaaatt aaacacctca aaaaatccta tggacaaaac gaagtgctaa aagacatttc
    26461 actcactgtc cacaagggag aggtcatctc tatcatcgga agctctggaa gcggaaaatc
    26521 gaccttccta cgctccatta acctacttga aacaccaact gatggacaaa tcctttatca
    26581 tggacaaaac gtcctcgaaa aaggctatga cctcacgcaa taccgtgaaa agttggggat
    26641 ggttttccaa tcctttaacc tctttgaaaa tctcaatgtt cttgaaaaca caatcgtcgc
    26701 tcagacaact gtcctaaaac gcgaacgcac agaagctgaa aagattgcca aagaaaacct
    26761 ggaaaaggtc ggcatgggag aacgctactg gcaagccaaa ccaaaacaac tctcaggtgg
    26821 tcaaaaacaa cgtgtggcca tcgctcgtgc cctctccatg aatccggacg ctattctctt
    26881 tgatgaacca acatcagctc tcgatccaga aatggttgga gaagtcctca aaatcatgca
    26941 ggacctggct caggaaggct tgaccatgat tgtcgtaacc catgaaatgg aatttgcccg
    27001 tgatgtctct caccgtgtta tctttatgga taagggcgtg atcgctgaag aaggtaaacc
    27061 agaagacctc ttcaccaatc ctaaagaaga ccgaacaaaa gagttccttc aacgctatct
    27121 caaataaaaa gaaaaggctg catcaaccgt gcagtctttt tgctgtcctc aaaatgaaaa
    27181 ggcagattct ctatctctac tacttgaagg tcaagaatcc gccgttatcc aaagattaat
    27241 cttcaaattt ttcataattt ttttcataga aatcaattaa gcctagggct gtttcaaatg
    27301 aaatattttt tacttttgca cgaccctgcg ccagagcaat gatagacatt tcacgcgcat
    27361 tcgtttcttt agagatacgg tagcctgtga ttttcttatc acgaacccag ccaacaactg
    27421 attctacttt ttcaaagttt gacttagcca tgtttttctc ctattttctt ctttataata
    27481 tttaattgta tacgttttta ctacttttgt caataaaaaa aacatatatt caacgaaaat
    27541 aattagttca gaattttctt acttcctttt taaatccgat aatatatagg ttttgctagc
    27601 ctctacacca taaatatttg ctaataaaac tactgtatta ttaccctctt aaggtgcgaa
    27661 attattcaag ttcttaaaaa atgcttctct atttccgtaa gatagcttat ttcttcgatt
    27721 taagaactga agatgatagt tctaaccttt agaaatccaa gccttcacta gctcaaaaac
    27781 tcctatcttt cttcctcaat aaatcatctg agagataggt atttcttata tccttcaaat
    27841 tcatcactcc tttggatatt gaggtgctag cctagaagca gacacccgat tatctaaacc
    27901 atccttaata gagatgacaa gacagataag ctcagttaat tacttatata tctttttaat
    27961 atggtatatt tgtcaacaaa aagaaatcaa atcatacctt atactcaatg aaaatcaaag
    28021 agcaaactag gaagctagcc gcaagttgct caaaacactg ttttgaggtt gcagatagag
    28081 ctaacgtggt ttgaagagat tttcgaagag tattaaagac agtgtgacta tgcttgtcaa
    28141 tagataggaa atcaaaatga aggatggaaa tctgagccaa acatcataag tgctataatg
    28201 aacagaagta agaattgcac gataagtttt ctaaaaccat aggaatcgtc ccctttcttc
    28261 atcttcatta tagcatatat acatcagttg tacaaataat atgatatttt tttattagtc
    28321 ctcagacaag catattataa agcgtttcat taccatttaa gttaatataa gctggatcaa
    28381 aaccttccat tctacgaatc aaacctgcat aatcatgctt atctgctaaa gcgatcccaa
    28441 tcaatactgg gcctgttccc ttgctagctc gtttgatata ctcaaaacgt gtgatatcat
    28501 catttggccc caggatatca tttacaaact cacgcaaagc tcctggacgt tgtgggaaat
    28561 tgaccacaaa ataatgtttg ataccatcat aaatcaaggc acgctcttcc atttctggca
    28621 tacggttgat atcattattt cctccagaaa tgatacaaca aatggttttc cccttaatat
    28681 attcagctaa aacctctaaa gaggcgatac tagctgctcc agcaggttct gcgactatcc
    28741 cttgcttaga gtaaaggtca atcaaggttt cagaaatcaa tccctcatcg acacctacca
    28801 aagtttgaat atgttgacga gttgcttcat aggtcaactg acctaccttt tgcacagcaa
    28861 tcccatccgc aaatttatca atttccttga gtttgactgg acctccagcc tcaaaggcag
    28921 ctttcatgga acgcgctcca ttcgcctcta ctccgataac ctcaatctct ggacttgttt
    28981 ccttgatata ggtagaaacc ccggcaatga gaccgccacc accaacagga accaagacag
    29041 catcaaaatc aatcgattct tttcgagctt cttctaaaat ctcataagca actgttcctt
    29101 gacctgcttg aacatgagca tcatcaaaag gatcaataaa ggtacgattt tcagagactg
    29161 taaattcttg agctgctttg gctgaggcat caaaggtatc tccaactagt ttaatagtta
    29221 caaaatcccc accaaaaaag cgaacctgac caatcttttg ttgtggcgta gtaatgggca
    29281 taaagatagt agcaggaatt ttcatttcat tacaagtata ggctactccc tgcgcatgat
    29341 ttcccgcaga agcgcaaact accccacgtt cacgttcttc cttgctgagc tgggaaatgg
    29401 cataataggc accacgaatt ttaaaggagc gaacacgctg ggcattttct tttttcaaat
    29461 aaatcttagc accatacttc tccgataaat aatgatcgta atccagtgga gtattcacaa
    29521 ccacaccgtt caagaccttg tgagccttga ttatatcttt tgaacttaac atataaaacc
    29581 tctttttcta taaaaaacag tcactaatga ctgtttttta gttattcatc tccgaaaatt
    29641 tcagtaacac tttcatggta tttatgagcc atacgaatcg aaaactcttt aggaagttca
    29701 taacgatttg tggaaatcca atcatataac cattctacca aactttcttc actatcatta
    29761 cgatggaaga taaaatagtt taaaatttct ttatattcta catcattcaa atccaacgtg
    29821 tctacaaatt gactacgagg aacaaaatta gaatctaatt ttcttagttg atctgtcaat
    29881 tctcccaatt gtaaatccaa ctgaaaaaat agtttttgca gttgcctatc agtttcatca
    29941 catcctgtct tgatagaaaa caaattggta atattcatat gatttcaacc cctaaataag
    30001 tacatctaat atcccacgaa tagctgaagc taaagttttc gcagtccagt catttaaacc
    30061 cgattctttc aatccagatg caataatttg ctctatttga tataaaccgc catctatcgt
    30121 ctcatttatt ctgcgaagag gaccttcaat ataggataaa gcttctccga atctaacagc
    30181 tgatttaggt cctaatgatt taccaactat atttgttaat attttttatt tctcaaaatc
    30241 catttcgcta tataacgagc agatttagtc gcaccagctc tctcaaacgg agaatgaatt
    30301 tcaagacctt cttctctagc tatttgtgcc aatttgaaga attgttcaaa ggtcatatgc
    30361 aacctaccat cttcaaaatt agcatcatca taaatgttaa ttacagcatt ttcatcatac
    30421 gaccaatctg ctttattttg gtctgctagc actattaccg acggtgtaat tacattatac
    30481 aactagaacc aataataacg atgcaatttt tctcataatc tttttcataa aatcatctcc
    30541 agcgctatat atttctaatt agttatagat tttgaatgca tcatcgtcgt ttttaccaac
    30601 gaatggcatt gctttacgca attctgcacc aactttttca atttcaaggt tagctgcttg
    30661 ttcacggtaa gcagtcaatt ttggacgtcc agctttatag tcatttacaa agtcatttgc
    30721 aaatttacca ttttggatgt ctgccaagac agccttcata ttttctttaa cttgttcagt
    30781 gattacacgt ggacctgata catagtcacc gtattcagca gtgtttgaaa tagattgacg
    30841 cattttcttg aatccacctt cgtagatcaa gtcaacgatc aatttcattt cgtgaagaac
    30901 ttcaaagtaa gccaattctg gagcgtaacc tgcttctgtc aagacttcga aacctgcttc
    30961 gataagggca gtcaaaccac cacaaagtac agcttgttca ccaaacaaat cttcttcagt
    31021 ttcttctttg taagttgttt caagaagacc tacacgagcc gctccaacac ctttacacca
    31081 gtccatagca atgtttttag catttcctgt tgcatcttgg tatactgcat aaagagctgg
    31141 aacaccaaat ccttcttcgt aagtacgacg taccaagtgt cctggtcctt taggagcaca
    31201 catgaagaca tctacatccg caggaacttt gataaattca aagtggatgt tgaaaccatg
    31261 ggcaaatcca actgcgtttc cagcttccaa gtttggagcg atttctgctt cgtacaattc
    31321 ttgttgaatt tcgtctggcg ccaagatcat gataacatca gccaacttag tagcttctgc
    31381 tactgtgtaa gtatcaaatc catcttcttt tgctttatca aaagatttac ctggacgtac
    31441 accgataata acgtcacgac ctgaatcacg caagttttga gcatgcgcat gcccttgtga
    31501 accataaccg ataacggcga tttttttacc gtcaagtgct gctactttaa catctttttc
    31561 atattccatt tgaactgtca tagcttttct ctcttttcta ttatttattg ccttttaagc
    31621 tggtttaaca aatttaagtt ggatttttaa tcgcgggtaa atccagttgc acccgttcga
    31681 gcaatattgc gaataccgta tgggcgaatg actcgcaata gggcttcgct cttttctgca
    31741 tttcccgtca tctgaatggt aatcgagctt ggcgctacgt ctaccactgt tgcacggaaa
    31801 ggttgaataa tcgctaaaat ctcagctctc ttctcagctg gcgctgacat cttaaccaaa
    31861 atcacctcgc gctccaaatg aggcttgtct gtaatatctc gaatgcgaat cacatcaatc
    31921 tgacgattga gctgtttgat gatttgctcc acttcatcat gagaagcaac atcaataata
    31981 atagtgatac gcgatacatt cggatcttct gttgctccaa cagagatgct ttcaatatta
    32041 acctgacgac gagataggac acctgtaaag cgattgagga ctcctgaacg attttgtagt
    32101 tttgctgtta acattctacg catggaactg cacccccaac atctcatgat tactcttacc
    32161 agccggtacc attggtaaca cctgttcctt acgagaaata tctacctcaa ttagcatagg
    32221 aacatcctca gtgatgactt caaggtcttg agccaaggtc tcaggattgt caaacttata
    32281 gtttttaata ccataagcct gcgccatcaa ttggaaatca ggaagggtat caaagaccga
    32341 ctctgatgtt ctgccttcat agaaggattc ctgccactgg cgaaccattc cgagtgaatg
    32401 attgttcagc ataaccacct tgattggcac cttgtaaata ttcaaaatag ccaactcctg
    32461 gttggtcatt tggaaaccac catccccaac aaacaagact acttccttat ctgggttagc
    32521 aattttagca ccgattgctg ctggaattcc aaagcccatt gttcccaaac cacctgaagt
    32581 cactaactga cgttcatttt ggtagggata atactgagct gtccacattt ggtgttgacc
    32641 aacgtctgtt accacaatgg catctccatt cgtcaattca ccaattcgtt caataactgc
    32701 ttgcggttga accacacgct ctttcttgtc atacgaacga acacgattct tgtctttagt
    32761 gactttctca atccactttt cagtattgtt gtgaactgtt ggttctgcta gcaacatttg
    32821 caaggccttc ttagcatctc caactacagg aatgtctgca ctgataatct tgccaatctc
    32881 agctgggtca atatcaatgt gggcaacctt agcattctta gcgaaagtct taggattccc
    32941 cgtcaaacgg tcatcgaaac gagaaccaat actaatcata aagtccgctt ccgtcatggc
    33001 aatatttgct gcgaatgacc cgtgcatgcc tcccattcca agaaagagtg ggtgactcgt
    33061 tgcaatcgtt ccttgtccca aaagactggt taccactgga atttgatagc gttctgcaaa
    33121 ttcatttagt tccgtagcag cctcagcata actaattcca ccaccagcta acaagactgg
    33181 ctttttagcc ttggacaatt gcttcaagat tttcttgatt tgcatatcat tcggctcaag
    33241 agtcggctga taacttggta aattcacttc tggtgaataa atgaagtctg tttctaaagc
    33301 agatatgtct tttggtaggt caattacaac tggccctgga cggcctgtag ttgcgatatg
    33361 gacagcttcc gtaatgatac gcggaatatc agctgtctca cgaacttggt aattgtactt
    33421 agtgattggc atggtaattc ctacgatgtc tgcctcctga aaggcatcct tcccaatccc
    33481 tgctcgcgcc acctgacctg taaagaccaa aaggggaacg ctatcgctca tagcatccgc
    33541 aatccctgta atggcatttg ttgctcctgg tccactagtg acgacggcaa cacccaactt
    33601 tccagttgat ttggcatagc cttcagcttc atgcaaacaa ccttgctcat ggcgccctag
    33661 aatgtggcga atgcctttaa aattatatat cgcatcataa aaaggcaaaa ccgcaccacc
    33721 aggataacca aagatggtat caactcctaa atcacgaagt gtttccaaaa ctaggtccga
    33781 ccccgtctta ggagattcta aactgatttt ctccattatt cccctttctt tcctcttaaa
    33841 aataacttgt tactatcata ccattttttc aaaatttttc aagataaaag aagaaatttt
    33901 ctgaattttc tattttaacg tttatttatg aatgttattt ttgtttttat taaaaagata
    33961 ccgatttcat ttactaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
    34021 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
    34081 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
    34141 caccgacata gaaggttacg atttcactgt cttcatccaa catatgtttc aaggtttcag
    34201 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctaaat
    34261 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
    34321 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
    34381 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
    34441 ctaccgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
    34501 tgtttggcaa gaagatgatg ttacgggcat taacctgttc aacagccttg ataaagtctt
    34561 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
    34621 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
    34681 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
    34741 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
    34801 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
    34861 ctccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
    34921 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
    34981 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
    35041 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
    35101 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
    35161 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
    35221 cttcaacagt gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
    35281 aaactgtcaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
    35341 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
    35401 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
    35461 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
    35521 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
    35581 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
    35641 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
    35701 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
    35761 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
    35821 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
    35881 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
    35941 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
    36001 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
    36061 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
    36121 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
    36181 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
    36241 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
    36301 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
    36361 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
    36421 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
    36481 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
    36541 ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
    36601 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
    36661 attttcttac aacaatatct gaatccaaat acagtacacg agactcgctt acatactttg
    36721 gaataaaata cctaaaaaaa gccgcatatg aaagtccctc aaaggggaga cgataacctt
    36781 tcagaatact actgtcaatc tgaacattca caatctcact attcaaagtc tctagtcttt
    36841 tttccatcaa ttggaaccat tctcgcggaa ggtcatcatt aaaaacataa aacttaagat
    36901 tataatgatg aacacaaaga gattttattg ttgtttcaac tttatccata taagcattat
    36961 ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatcttatt tctttttatt
    37021 cccatcatat tattcccatc atatgtttct acgtaaccat tattttcgcc tattcgttcg
    37081 taaaaccata ccagtggaga ttttagatga agtcccatta cggtttacaa tttttacatt
    37141 acgacacgga gttttacaaa tcgatttcat ttgccaaacg tagttagtga ggcagttagc
    37201 tagttcgcca aatagcgact agcgtccaac aatttggaac tttagctcca attgttggta
    37261 ctgagtcaca tcttctcctc taactctacg tctggatact tgtccgcaaa ccagcggagg
    37321 gcaaagtcat tttcaaagag aaagactggt tggtcaaaac ggtctttggc taagatattg
    37381 cgacttgacg acatccgttc atccaagtcc tcaggcttga tccaacgaac ggtcttttta
    37441 cccattgggc tcatgaccac ttccgcattg tattcgcctt ccatacggtg tttaaagact
    37501 tcaaactgga gttgaccaac agctcccagc atgtactcac ctgtttggta attcttataa
    37561 agctgaacgg ctccttcttg caccaattgc tcaatcccct tgtggaagga tttttgcttc
    37621 ataacattct tggcagaaac tttcatgaaa atttcaggag taaaggttgg cagtggttca
    37681 aattcaaact tgttttttcc aaccgtcaag gtatccccaa cctgataagt accggtatcg
    37741 taaaccccga taatatcacc tgccacggca ttgatcacat tctcacgact ttccgccata
    37801 aactgggtaa cattagatag tttagccccc ttaccagtac gagggagatt gacactcatg
    37861 ccgcgctcaa attcgcctga tacgatacgg acaaaggcaa tacggtcacg gtgacgagga
    37921 tccatgttgg cttggatttt aaagacaaag cctgagaaat ccttgtcata aggatccaca
    37981 atttcaccgt ctgttttctt gtgaccatgt ggttctggag caaacttgag gaagatttca
    38041 aggaaggtct gcacaccaaa gtttgtcagg gctgaaccga aaaagacagg cgtcaattct
    38101 ccagccagaa tagcttcctc tgaaaactca ttcccagctt catttaaaag ctcaatgtca
    38161 tccttgactt gctcgtagaa aggattgcta ccaaagagtt tgtccccgtc ttctagactg
    38221 gcaaaacgct catccccttt gtaaagctct aaacgttggt tatagaggtc atacaagccc
    38281 tcaaaggctt tccccatccc gataggccag ttcatagggt agctagcaat gcccaagatt
    38341 tcttccaatt cttgcaagag atccaaaggc tcacgaccgt cacggtccag cttgttcata
    38401 aaggtaaaaa ctggaatgcc acgatgtttc acaacctcaa acaatttctt ggtttgagcc
    38461 tcgatcccct tggcagagtc cacgaccatg accgcagcat ccaccgccat caaggtacga
    38521 taggtatctt ctgagaagtc ctcgtgccct ggcgtgtcta agatattcac gcgcttgccg
    38581 tcgtagtcaa attgcataac agatgaagta acagaaatcc cacgttgctt ctcgatatcc
    38641 atccagtcag atttagcaaa agtccctgtt ttcttccctt ttaccgtacc agcctcacga
    38701 atctcacccc caaagtagag taactgctca gtgatggttg ttttccccgc gtccgggtgg
    38761 gagataatgg caaaggtacg acgtttctta atttcttctt gaatattcat aagttctctt
    38821 tctttgattc tctatttttc ttgtttcaat agctgagaat gatttttaca ttggatttta
    38881 ccattccttt caatactcca ttatatcgga ttttagcatt tttttcaatt tctatctctt
    38941 ttcacttccc cctcccttat ttataggaaa atatggtaaa atagaacaga ctaaaaatca
    39001 tcatttcacg aaaggatgca agatgaaaat tacgcaagaa gaggtaacac acgttgccaa
    39061 tctttcaaaa ttaagattct ctgaagaaga aactgctgcc tttgcgacca ccttgtctaa
    39121 gattgttgac atggttgaat tgctgggcga agttgacaca actggtgtcg cacctactac
    39181 gactatggct gaccgcaaga ctgtactccg ccctgatgtg gccgaagaag gaacagaccg
    39241 tgatcgcttg tttaaaaacg tacctgaaca agacaactac tatatcaagg tgccagctat
    39301 cctagacgat ggaggagatg cctgatgact tttaacaata aaactattga agagttgcac
    39361 aatctccttg tctctaagga aatttctgca acagaattga cccaagcaac acttgaaaat
    39421 atcaagtctc gtgaggaagc cctcaattca tttgtcacca tcgctgagga gcaagctctt
    39481 gttcaagcta aagccattga tgaagctgga attgatgctg acaatgtcct ttcaggaatt
    39541 ccacttgctg ttaaggataa catctctaca gacggtattc tcacaactgc tgcctcaaaa
    39601 atgctctaca actatgagcc aatctttgat gcgacagctg ttgccaatgc aaaaaccaag
    39661 ggcatgattg tcgttggaaa gaccaacatg gacgaatttg ctatgggtgg ttcaggtgaa
    39721 acttcacact acggagcaac taaaaacgct tggaaccaca gcaaggttcc tggtgggtca
    39781 tcaagtggtt ctgccgcagc tgtagcctca ggacaagttc gcttgtcact tggttctgat
    39841 actggtggtt ccatccgcca acctgctgcc ttcaacggaa tcgttggtct caaaccaacc
    39901 tacggaacag tttcacgttt cggtctcatt gcctttggta gctcattaga ccagattgga
    39961 ccttttgctc ctactgttaa ggaaaatgcc ctcttgctca acgctattgc cagcgaagat
    40021 gctaaagact ctacttctgc tcctgtccgc atcgccgact ttacttcaaa aatcggccaa
    40081 gacatcaagg gtatgaaaat cgctttgcct aaggaatacc taggcgaagg aattgatcca
    40141 gaggttaagg aaacaatctt aaacgcggcc aaacactttg aaaaattggg tgctatcgtc
    40201 gaagaagtca gccttcctca ctctaaatac ggtgttgccg tttattacat catcgcttca
    40261 tcagaagctt catcaaactt gcaacgcttc gacggtatcc gttacggcta tcgcgcagaa
    40321 gatgcaacca accttgatga aatctatgta aacagccgaa gccaaggttt tggtgaagag
    40381 gtaaaacgtc gtatcatgct gggtactttc agtctttcat caggttacta tgatgcctac
    40441 tacaaaaagg ctggtcaagt ccgtaccctc atcattcaag atttcgaaaa agtcttcgcg
    40501 gattacgatt tgattttggg tccaactgct ccaagtgttg cctatgactt ggattctctc
    40561 aaccatgacc cagttgccat gtacttagcc gacctattga ccatacctgt aaacttggca
    40621 ggactgcctg gaatttcgat tcctgctgga ttctctcaag gtctacctgt cggactccaa
    40681 ttgattggtc ccaagtactc tgaggaaacc atttaccaag ctgctgctgc ttttgaagca
    40741 acaacagact accacaaaca acaacccgtg atttttggag gtgacaacta atgaactttg
    40801 aaacagtcat cggacttgaa gtccacgtag agctcaacac caattcaaaa atcttctcac
    40861 ctacttctgc ccactttgga aatgaccaaa atgccaacac taacgtgatt gactggtctt
    40921 tcccaggagt tctaccagtt ctcaataaag gggttgttga tgccggtatc aaggctgctc
    40981 ttgccctcaa catggacatc cacaaaaaga tgcactttga ccgcaagaac tacttctatc
    41041 ctgataaccc caaagcctac caaatttctc agtttgatga accaatcgga tataatggct
    41101 ggattgaagt caaactagaa gacggtacga ccaagaaaat cggtatcgaa cgtgcccacc
    41161 tagaggaaga cgctggtaaa aacacccatg gtacagatgg ctactcttat gttgacctca
    41221 accgccaagg ggttcccttg attgagattg tatctgaggc agatatgcgt tctcctgaag
    41281 aagcctatgc ttatctgaca gccctcaagg aagttatcca gtacgctggc atttctgacg
    41341 ttaagatgga ggaaggttcg atgcgtgtgg atgccaacat ctcccttcgt ccttatggtc
    41401 aagagaaatt cggtaccaag actgaattga agaacctcaa ctccttctca aacgttcgta
    41461 aaggtcttga atacgaagtc caacgccagg ctgaaattct tcgctcaggt ggtcaaatcc
    41521 gccaagaaac acgccgttac gatgaagcga ataaagcaac catcctcatg cgtgtcaagg
    41581 aaggggctgc tgactaccgc tacttcccag aaccagacct acccctcttt gaaatttctg
    41641 acgagtggat tgaggaaatg cggactgagt tgccagagtt tccaaaagaa cgtcgtgcgc
    41701 gttatgtatc tgaccttggt ttatcagact acgatgctag tcagttgact gctaataaag
    41761 tcacttctga cttctttgaa aaagctgttg ccctaggtgg tgatgccaaa caagtctcta
    41821 actggctcca aggggaagtc gctcagttct tgaatgctga aggtaaaaca ctggaacaaa
    41881 tcgaattgac accagaaaac ttggttgaaa tgattgccat catcgaagac ggtactattt
    41941 catctaagat tgccaagaaa gtctttgtcc atctagctaa aaatggcggt ggcgcgcgtg
    42001 aatacgtgga aaaagcaggt atggttcaaa tttcagatcc agctatcttg atcccaatca
    42061 tccaccaagt ctttgccgat aacgaagctg ctgttgccga cttcaagtca ggcaaacgta
    42121 acgccgacaa agcctttaca ggattcctta tgaaggcaac caaaggccaa gccaacccac
    42181 aagttgccct taaactactt gcacaggaat tggcgaagtt gaaagaaaac tagacagaac
    42241 aaaaccagcc ctaaggttgg ttttttcttc tctaccaact cccaataact attttggctt
    42301 tatttccaga gtattttatg gtaaaatgaa gagtaataat atttattaaa gaggtaaaaa
    42361 catgattgaa gcaagtaaat taaaagctgg tatgaccttt gaaacagctg acggcaaatt
    42421 gattcgcgtt ttggaagcta gtcaccacaa accaggtaaa ggaaacacga tcatgcgtat
    42481 gaaattgcgt gatgtccgta ctggttctac atttgacaca agctaccgtc cagaggaaaa
    42541 atttgaacaa gctattatcg agactgtccc agctcaatac ttgtacaaaa tggatgacac
    42601 agcatacttc atgaatacag aaacttatga ccaatacgaa atccctgtag tcaatgttga
    42661 aaacgaattg ctttacatcc ttgaaaactc tgatgtgaaa atccaattct acggaactga
    42721 agtgatcggt gtcaccgttc ctactactgt tgagttgaca gttgctgaaa ctcaaccatc
    42781 tatcaaaggt gctactgtta caggttctgg taaaccagca acgatggaaa ctggacttgt
    42841 cgtaaacgtt ccagacttca tcgaagcagg acaaaaactc gttatcaaca ctgcagaagg
    42901 aacttacgtt tctcgtgcct aatctctaga aagaggtcat tctatgggaa ttgaagaaca
    42961 acttggcgaa atcgttatcg ccccacgtgt acttgaaaaa atcattgcta tcgctactgc
    43021 aaaggtagag ggtgttcact ctttttcaaa cagatcagtg tctgataccc tttcaaaact
    43081 ttcactcggc cgtggcattt atcttaaaaa cgtggacgaa gaactcacag cagatatcta
    43141 tctctacctt gagtacggag taaaagttcc taaggtagcg gttgctatcc agaaagctgt
    43201 caaagatgcc gtccgtaata tggctgatgt agaactcgct gctatcaata ttcacgttgc
    43261 aggtatcgtc ccagataaaa caccaaaacc agaattgaaa gatctatttg acgaggactt
    43321 cctcaatgac tagtccacta ttagaatcta gacgccaact ccgtaaatgc gcttttcaag
    43381 ctctcatgag ccttgagttc ggtacggatg tcgaaactgc ttgtcgtttc gcctatactc
    43441 atgatcgtga agatacggct gtacaacttc cagccttttt gatagacctc gtttctggtg
    43501 ttcaagctaa aaaggaagaa ctagataagc aaatcactca gcatttaaaa gcaggttgga
    43561 ccattgaacg cttaacgctc gtggagagaa acctccttcg cttgggagtc tttgaaatca
    43621 cttcatttga cactcctcag ctggttgctg ttaatgaagc tatcgagctt gcaaaggact
    43681 tctccgatca aaaatctgcc cgttttatca atggactgct cagccagttt gtaacagaag
    43741 aacaataaaa agaaaaagtg tttgatatct atcaaacact ttttctttgc ctcccactat
    43801 ctaaaaaaat gataatagat ataattgtaa acaaaaatcc agataggttt tgcatgattg
    43861 agaaagttaa aaaaactatg gcagagaatc gttaatctca gattgtcggt agaacgataa
    43921 acaagggcaa aaaagaaacc aatcagacta taatataata aactaattgg atctctgtga
    43981 gatagtatca aatgactaag cccaaagata aggcctgata agatgacatc taaataatac
    44041 ttggactagg gaaagaaggt attcataaaa taccctctat caagagtctc ctcaaaaaca
    44101 ggaccgatga ttacaggcag gacaaaagat aagatagtcg ataaaaaggt tggttgtcca
    44161 tttgaaagaa ccacggtaaa atactcatca tgaatattcc tatgattaat caaatgagca
    44221 tagcgtgccc aaaaattacc gagaatctga taaaccacat aagttgcaaa taaggagaag
    44281 acaaatgacc agttccagct ctttttcttt tttaacctcc aaattaatag aaaaggaaac
    44341 ttcccactaa tcccactgtt aaaataagag aatagacatc agctcctaac cctaaaatga
    44401 tcgtcacata caatccaatt gtttgtggta aataggtaga tagtaaaata ataagcaaaa
    44461 atattccaaa ttgtcttagt ttctttgtgt ttctcatcgt acttttttga aagattaccc
    44521 tgttcggaag ccgtacttcc aagcatctat ataagaatta agtgcccctt gcctcatata
    44581 gggagcaaat tctctataat ataaccatct actatatcca tcttcccaaa cagcaagacc
    44641 acctgaagtt tgctccaagt cctcagttga aataactgta aatgtttctg tacctgtcat
    44701 tgcaagtacc ttcttaaaat agattgttgt aggctcacat ttatagtata tttctttttt
    44761 tgtctatttt atagtctatc tcctcaactg gcaatttttc gacctgaatt gcatttttcc
    44821 ataaaaaatg agacctttct agtctcattt agtcattctt agtattttct aaatcgttga
    44881 tagcgttctt ccagcaactc ttctagcggt ttttgtgaaa gtctagccag ctccgtttgg
    44941 agttcttttt tgacactctt aattagttct ttactagaaa gtcctacttc agaaatcacc
    45001 ttatccacca cgtccatttc taacagttca tgcgaagtga ttttcatcag ttctgctgct
    45061 tccatggcgc gagtaccgtc cttccataaa atggaagcaa agccttctgg actgagaatg
    45121 gcatagatag aattttccag catccagaca cggtccgcga cagctagagc cagagccccg
    45181 cctgaaccac cttcaccgat aataatggcg ataataggaa ctttcaggtc actcatttcc
    45241 atgagattgc gagcgatagc ttccccttga ccacgttctt ccgctccgac accaggataa
    45301 gcacctgctg tattgataaa ggtcacaact ggacggccaa atttctcagc ctgtttcatc
    45361 aaccgcagtg cctttcggta gccttctgga tgtggttggc caaaattccg tttgaggttg
    45421 tcttgcaaac tcttgccttt ttggatacca accactgtta cagcttggtc tccaagccaa
    45481 ccaataccac caacaactgc accatcatca cgaaaagaac ggtcaccatg taattggata
    45541 aattcatcaa aaatgcctgt cgcaaagtcc aaggttgtca agcgactctg ctcacgcgct
    45601 tctctgacta tttttgcaat attcatctag gactccctcc atgcaatctg actaggctag
    45661 caatcgtatc tggtaagtct cttcttttga caatagcatc cacaaagcca tgttctaata
    45721 ggaattctgc cttttggaaa tcctcaggca agctttcacg aaccgtattt tcaatcacac
    45781 gacgcccagc aaaaccaacc aagctctgtg gttcagccag aatgatatcg ccttccatag
    45841 cgaaagaagc tgtcacacca ccagtcgttg gatctgtcaa aatggtcagg taaaagagac
    45901 cagcatttga atggcgttta accgctgcag agatcttagc catctgcatg agactcatga
    45961 ttccttcctg catacgggct ccaccagagg ctgtgaatag gacaactggc aatttttcga
    46021 cagtcgcata ctcaaacaaa cgagtgattt tttcacctac aaccgtaccc atagaagcca
    46081 tgataaaatt agaatccata atcccaagag ccacagtctg acctttaata agagcagttc
    46141 ctgtcacaac ggcttcatgc agacctgttt tttcacgcat agatgccagt ttcttttggt
    46201 aaccagggaa atgcaaggga tccttgcttt caatccctgt aaacaattct ttgaaggttc
    46261 ccatatcaat cgtcaaagcc aagcgttctt gggcagaaat acgaaaggta tagctacagt
    46321 gcggacagat acgttcactt cccagatcct tctgatagat ggtatgctta cagcctggac
    46381 actgggaaaa taattcatct ggaacctctg gcttagcttg aggtttttcc ctaaccgaac
    46441 gattgggatt gattcgaata tacttatctt ttttactaaa tagagccatt gattcccctt
    46501 ttcggtttaa actcttaaag tcattttatt ctttttcttg atatttaggt aagaaggttt
    46561 ccatcaagaa ggaagtatca taatccccag caatgacatt gcgatctgaa atgagatcaa
    46621 gctggaaatc tgcattggtc tgcactcctt caatctctaa ttcatagagg gcacgttgca
    46681 ttttcatcaa ggcgtcaaaa cgattttcgc cgtgtactat gattttggca atcatactat
    46741 cataataagg cggaatggta taacctggat aaactgctga atccacgcgc aagccaactc
    46801 caccacttgg cagatagaga ttagtaatct tacctggact tggagcaaag ttaaaggctg
    46861 ggttttctgc attgatacga cactcgatgg catgaccgcg taggacaata tcttcttgct
    46921 taacagacaa aggctgacct gccgcaatgc aaatctgttc cttaacgata tcaacacctg
    46981 aaacaaactc tgttactgga tgttctacct gaacacgagt attcatctcc atgaaataga
    47041 aatttctact tgcttcatca agaagaaatt caatggttcc tgcattctca tagccaacaa
    47101 actctgccgc tcgaacagca gcagcaccta tttcatgacg cagcgttttt ccgattgcaa
    47161 tcgagggact ttcttccaaa accttttggt tattcctttg aagagaacaa tcccgttcac
    47221 ccaagtgaat cacatgtcca tgctcatcac ctaggatttg aacctcaatg tgccgagctg
    47281 gatagataac ccgttctatg tacatggcac cattgccata attggccttg gcctcactag
    47341 aggcagtttc aaaggcagaa acgaggtcat ctggtttttc aaccttacga atccctttac
    47401 cacctccacc tgctgaagcc ttgagcataa caggatagcc aattttttca gcaacaatca
    47461 aagcttcttc agagttatgc acttctccat ctgaacctgg tataacaggc acacctgctt
    47521 taatcatctg agcacgcgca ttgatcttat cccccatcat atccataaca tgaccagatg
    47581 gaccgataaa cttgatacct acttcttcac acatggtcgc aaatttggaa ttttcactga
    47641 gaaatccaaa accagggtga atagcttctg cctcagtcaa gactgcagct gatagaactg
    47701 cattaatatt gagataagac tctgttgcct tgccaggacc aatacaaact gcttcatctg
    47761 ccaaaagcgt atgaagagct tccttatcag cagttgaata aaccgctacc gtcgcaatcc
    47821 ccaattcacg tgccgcacgg ataatacgaa ccgcaatttc accacgattg gcaattaaaa
    47881 tttttcgaaa catggagaac ctccttagtt cccaattgca aaagtaagga taccactggc
    47941 tgcaagcttg ccatccactt cagcctttgc ttcaaccaca gctatggtgc cacgacgttt
    48001 tacaaaagtc gctgtcataa ccaattggtc gcctggtaca acttgcttct tgaacttaac
    48061 cttgtccata ccagcgtaaa agaccagttt tcctttattt tcaggttttg ataactccaa
    48121 cacaccagca gtttgcgcca aggcttccat aatcagaaca cctggcataa ctgggtattg
    48181 aggaaagtgg ccgttaaaga aaggttcgtt aatggtcaca tttttgatag caacaatggt
    48241 atcctcgctc acttccaaga cacggtccac tagaagcata ggataacggt ggggaagagc
    48301 ttctttgatt ccttgaatat cgatcatttg atacgtacca atcctttacc aaactcaacc
    48361 atttcttcgt tagagacgag aatttccgtt accacaccat ccttaggagc tgggatttca
    48421 ttcatgactt tcatggcttc gataattacc aatgtttgac cttttttgac actatcacca
    48481 actgtaacga aggcaggttt atctggtcca gcagccaagt aaaccactcc aacaagtgga
    48541 ctctctacaa gatttccctc agtagccaca cttgcttcag ctggagctgg aacttcttct
    48601 gctacagtct ctgctggagc agatgtagga gctactggac tcggtgttgc tagaacgggt
    48661 gctggagcga cttgagttgc aacttcaggc acaggtcttg cttcattctt gctaaactgc
    48721 aactcatccg tcccattttt ataagaaaat tctctcaaac ttgactggtc aaattgagtc
    48781 atcaagtctt taatatcgtt taaattcata cttatctatt ctcccaacgt ttgaaagcaa
    48841 gaactgcatt gtggcctcca aaaccaaaag tatttgaaat agcgtatgga atttctttct
    48901 ccaaaccttg tccataaacg acattagctt cgatataatc tgatacttca cttgtcccag
    48961 ctgtcattgg tacaaagtta tgacgcatag cttcgatggt gacgatagct tctactgcac
    49021 ccgcagcccc cagcaaatgt cctgtaaaag acttggttga tgatacaggt acttccttac
    49081 caagaacagc tacgatagca ccactttctc ctttttcatt ggcaggagtt gacgttccgt
    49141 gagcattaac ataggctact tgctctggag aaatctcagc ttcttccaag gctagtttga
    49201 tggccttgat agctccctga ccttctggat gtggagaagt catgtggtag gcatcacaag
    49261 tatttccgta accaaccact tcagccagga tagtagctcc acgtttttca gcgtgttcaa
    49321 gactttctag aaccaacatc cctgaacctt cacccataac aaacccattg cgatccttat
    49381 caaatgggat cgaagcacga gttggatcct ctgtagtaga gagagctgtt aaggcttgga
    49441 aaccagcgat ggcaaaaggt gtgatagaag cttctgttcc tcccaccaac atcacatctt
    49501 ggaaaccaaa cttaatggag cggaaggcat ccccaatcgc atcatttgat gaagagcagg
    49561 cagtattgat agatttacaa acaccgtttg caccaaaacg catggctaca ttcccagaag
    49621 ccatatttgg taaagctttt ggaagagtca ttggtttgac acgtttgggt cctttttcat
    49681 gaaggcgaag tacctgatct tcaatttcct tgattccacc aataccagat gcaacgataa
    49741 caccaaaacg atccctatta agagcctcta catcaagatt ggcatggttt acagcctctt
    49801 gggctgcata caaggcatat aaagaatagt tatcaaaacg gttggtatct ttttttacaa
    49861 agtatttatc gaacggaaaa tcttggattt ctgccgcatt atgcacatca aagtcactat
    49921 gatcaaattt tgtaatgcca ccaatgccga ttttcccagt tgctaaacta ttccaaaatt
    49981 cttctggtgt atttccgatt ggagatgtta ctccataacc tgttaccact actcgattta
    50041 gtttcattct tttcacctct agctttcgct acatacttaa gccaccatca atggcaatca
    50101 cttgaccagt tagataatct tggcctgcta aaaatactgt caaatctgca acctgctctg
    50161 cctgcccaaa ttctttcatc ggaatctgag ctagtgtagc ttccttaatc ttatctgata
    50221 agatagctgt catatcagac tcaatcattc ctggagcaat cacattgact cgtatattcc
    50281 gactagcgac ctcgcgtgcc acagacttgg taaagccaat caagccagcc ttagaagcag
    50341 catagttagc ttgaccaata ttccccatca aaccaacaac actagacata ttaatgatag
    50401 caccttctct ggctttcatc atcggtttca agactgattg tgtcatatta aaggcaccag
    50461 tcagattgac cttgagcact ttttcaaaat ctgcttctgt catcttgagc ataagagtat
    50521 cttgggtaat ccctgcattg ttgaccaaaa catctactga acccagttct gcaatagctt
    50581 gatcaatcat acgcttagcg tctgcaaaat ctgatacatc tcctgaaatg ggaaccacct
    50641 tgataccata gtttgaaaac tcagcgagca attcttctga gattgcccca cgactgttta
    50701 agacaatgtt ggctcctgct tgagcaaact tgtgggcgat ggcaagacca attccacgac
    50761 tcgaacctgt aataaagata tttttatgtt ctagtttcat ttttttcctt tcaaaacttc
    50821 tacttatttt agtctatttt tttaaaagtg ctactaaact cgcttgatct tccacatgag
    50881 ctaagtgagt agtttgatca atttttttaa caaaacctga caagactttc cccggtccaa
    50941 tctcgataaa gttgcttatg cctgcttctt gcatgacccc aatactttca tagaaacgaa
    51001 cgggttcctt gacctgacgc gtcaagagct gagcaatgtc ctctttttgc atcacagcag
    51061 cttctgtatt gccgactagg ggacaagtaa aatctgaaaa acttacctga gccagagttt
    51121 cagctagttt ctggctagca ggttcaagga gagaggtgtg aaagggacct gacaccttaa
    51181 gaggaatcaa gcgtttggca cctgcttctt gcaaaagttc aaccgctcga tcaactgcaa
    51241 ccacttctcc agcaatgacg atttgtgcag gtgtgttata gttggctgga gtaaccactc
    51301 caagttcaga agctttttga caggcttctt caatgacctc tactggcgta ttgagaactg
    51361 ctaccatctt gccagagtca gcaggagccg cttcttccat ataggctcca cgcttagcta
    51421 ccaaggcaac cgcatcttca aaatccaagg cgccgcttgc caccaaggca gagtattctc
    51481 caagagacaa accagcaacc atatcaggct gatagccctt ttcttgcaat aaacggtaga
    51541 tagcaaccga agtcgctaga atggctggtt gcgtatagcg ggtctgattg agtttgtctt
    51601 cttccgtatc gatgagataa cgcaaatcat aacctagcac ctgactcgct cgatcaatcg
    51661 tttctttaac aatcggatac tgatcataga aatcccgtcc catccctaga tactgggcac
    51721 cttgaccagc aaataaaaag gctgttttag tcatttctta caactcctgt ccagcgagag
    51781 gcttcttctt gaattttctt agcggctccg taatacaaat cttttaggat ttcttcagct
    51841 gtttcttctt tagaaacaag ccctgcgatt tgacctgcca tgacagagcc accctccaca
    51901 tcaccgtgaa caactgcttt ggctagggca cctgctccca tttgttcaaa gatttctaaa
    51961 tcaggatctt cctgcttaaa ggcatctttt tcagccagtt caaaatctct agtcaactga
    52021 tttttaatag cacgaacagc atgaccaaag tgctgagctg aaatcgtagt gtcaatatcc
    52081 cttgctttta aaattttctc cttgtagttt ggatgggcat tcgactcttt tgcaactaca
    52141 aaccgtgtcc ccacctgtac agcctctgca cctagcataa agccagccgc agcaccttca
    52201 ccatccgcaa ttcctcctgc agcaataaca ggaatagata cagctgtggc tacctgtcgc
    52261 accaaggtca tggttgttaa tttaccgata tgccccccag cttccattcc ttctgcaata
    52321 acagcgtctg caccgatttt ttccatgcgt ttagctaaag cgacactagg aacgacagga
    52381 ataacgatta tcccagcttc atggaaacgt tccatatact tgcttggatt tcctgctcct
    52441 gttgtgacaa ctttaacacc ttcttcaata acgagatcca cgatatcttc cacaaaggga
    52501 gataagagca tgatgttgac cccaaagggt ttatcagtca atgatttgat tttatcaata
    52561 ttggccttga caacttcttt cggggcattt cccccaccga taattcctaa tcctccagcc
    52621 ttggaaacag cccctgccaa atcaccatca gcaacccagg ccatccctcc ttggaaaata
    52681 ggatagtcaa tcttcaataa ttctgtaata cgcgttttca tagtgcctcc aaccttcctt
    52741 gcttacgtaa tagttcgatt tcaccataat ttgacagtca aactattacc taaacaagag
    52801 ggagtgggtt tctccctact ccttctacta atattctgct tattttgctt gctcttcaac
    52861 gtaagcaacc aagtcaccaa ctgttttcaa gtcattttct gcttcgattt ggatatcaaa
    52921 agcatcttcg atttctgaga ttacttggaa caagtccaat gaatctgcgt ccaaatcatc
    52981 aaaagttgat tcaagtgtta cttctgatgc gtcttttcca agttcttcaa cgataatttc
    53041 ttgtactttt tcaaatactg ccatgatagg actcctttaa aataaatagt ttttttataa
    53101 caatgtgttc accacatgat tacctaaatt gtaagaatga gcgtgcccca ggtcaaacct
    53161 ccaccgaagc ctgatagaag aacagtctgg ctaccatcta aagggatgag accttgttct
    53221 acacactctg aaagtaaaat cgggatactg gctgcactgg tattgccata ttccatcata
    53281 ttggctggaa gtttggctcg gtcaacacca atttttctag ccatcttatc caaaatacgg
    53341 tcattggctt gatgaagtag cagataatcc aagtctgtca cctctatagg agattcatca
    53401 atagtctgct tgatagactt ggctacatct cgaatggcaa aatcaaagac tgtgcgtcca
    53461 tccatcttca aaaacgaatc tgcactttct tgatctgaaa atggagaatg caaacctgaa
    53521 tgcccataag ttaaacactc gctgcgactt ccatcgctat tgagactctc agctaagaaa
    53581 tgctcttgct cgctagcttc taacaagaca ccaccagcac catctccaaa caacacagct
    53641 gttgatcgat ccgaccaatc gactgcctta gagagggttt cactaccaat caccaagcct
    53701 ttttgaaagc gaccagaagc gataaacttt tcagcagttg aaagagcaaa tacaaatcca
    53761 ctgcaagccg cggttaagtc aaaagcaaag gctttattag caccaatatt agcttgaaca
    53821 cgagcagctg tagagggcat catcgaatct ggagtaatgg tagctaggat gataaaatcc
    53881 agttcttctc ctgttattcc agcttttgcc atcagtttct tagcaacctc tgtagccaaa
    53941 tcactggtag attctgttct tgaaatatgc ctttgtcgta ttcccgttcg acttgaaatc
    54001 cactcatcat tggtatccat aatctgagcc aagtcgtgat ttgtaaccac ttgctctggc
    54061 acataatgag caacctgact tatttttgca aaagccatta tttcaaatcc tccaaaaatt
    54121 ggtaaagatt agtcaagcct ttacccatga cagcaatttc ttcctcgctc atgccatcaa
    54181 taattttttc taccatggcc ttgtggaagc gtttatgcag tctatgaatc aagcgaccct
    54241 tctttgtcaa atgcagatgc accacacgac gatcctgttc tgaccgaact cgctcaatgt
    54301 agcccttacg ctctaaattg ttcaaacttg tcgtaacagt tccaagagtt accattaact
    54361 cttttgacac ttgacttgga gtcacatctg gagccttacc gatgacatca attgtatgca
    54421 tttctttgat ggagatatcc ttaaaacgac tacctctcaa gttcacttcc tcaattacaa
    54481 ggacattgtt aaatatagat gttaaatatt cattgattcg ttggtagtcc atttttcata
    54541 tccctccttc ttcaaaaaac ttttacaatc aaaacatttg acagaaagaa ttatatcaaa
    54601 attcaaagaa tgatgcaagt attttttatt ttcctgtaaa tttaggtctt cttctctccg
    54661 aatgagctcg cactccttct ttgaaatcct ctgtttgagc taaggatttc tgtaggttca
    54721 gttctaaagt agcgtaaccc tgccagtctt taaattggct ctcccaaacc aacttcttaa
    54781 tggcagcata ggaattactt gaagcacgtc ttaatttttt aagaagctgt tctctcgtct
    54841 tttcaagttt ttcagcttca gaaacgcggt aaaccaaccc ccattctagg gctttttctg
    54901 ccgttaaagc ctctcctgtc atagctaatt gagcagcacg cgtcacaccg atactgcggc
    54961 tcaagagatg aattccccct gcatctggag ccaaaccaac accaacaaag gcttggataa
    55021 acttagcctt atccgtcgcc aaacagaaat ctgccgcaac agccatattc gctgcggcac
    55081 ctgcaacagc accgtcaact tccattaaaa caggtttggc tatttgcttg attttataag
    55141 aaatcgtatt gaccaactct gcgatttttg tcaatgatgg aatatcatcc tcatccactg
    55201 cccgcttcat ctctaccaaa tctcccccaa ctgagaagac ctttccattg gcattgatta
    55261 agataaaatg cacagctgga ttttcttctg ccaaagtcag agcttctaaa atctcctcac
    55321 acatgggaat atgaaaacca tttgcgacct caggacggtt caaggtaagg attgccaagt
    55381 cctcttcaag ctgataaata atgtgttcca tcagggctcc tttttatttt ataagcagtt
    55441 tatactcttc gaaaatctct tcaaaccgcg tcagcttcca tctgcaacct caaaacagta
    55501 ttttgagctg acttcgtcag tcttatttac aacctcaaag cagtgctttg agcagtctgc
    55561 ggctagcttc ctagtttgct ctttgatttc attgagtgtt aaattatttc actgtcaaag
    55621 tatatctttt ttaggagcag aaagcaagaa aaaatcgact gaaagtgtct cagccgataa
    55681 gaaaggctcg ctttaggcta gaaagcatct tattttcttc attgaaaaaa gcctttcttt
    55741 ctgctataat cgtataaaat acttacttta ggagttctta tgaaagttgt taaatttgga
    55801 ggtagttctc ttgcctctgc tagtcaatta gaaaaagttt taaacatcgt caaaagcgat
    55861 tcagagcgtc gttttgtagt cgtttctgcg cctggtaaac gcaatgctga agatactaag
    55921 gttacggatg ccctgattaa atactaccgc gactatgttg cgggtaacga tattagcaag
    55981 agccaaagct ggattatcga ccgctatgct gctatggtta gtgaattggg actaaaacca
    56041 gctgtgctag aaaaaatttc taaaagcatt cacgccttgg ccactcttcc tattgaagaa
    56101 aatgaatttc tctacgatac tttcctagca gccggtgaaa ataacaatgc caaattgatt
    56161 gctgcctact ttaaccaaaa tggtatcgat gcacgctata tgcaccctag agaagctggg
    56221 attgtggtca caagtgaacc tggtcacgct cgcatcattc catcaagtta tgacaagatt
    56281 gaagaattga caaacaccaa tgaagtcctt gtcattcctg gtttctttgg tgtcactaag
    56341 gaaaatcaaa tctgtacttt ctcacgtgga ggttctgata ttacaggttc tatcattgct
    56401 gctggtgtca aagccgacct ctatgaaaac tttacggacg ttgatggtat ctttgcagcc
    56461 caccctggta ttatccacca accacactcg attcctgagt tgacctaccg tgaaatgcgc
    56521 gagttggcct atgcaggctt ctcagtcctt catgacgagg ctcttcttcc tgcctaccgt
    56581 ggaaaaattc ctctggttat caagaatacc aacaaccctg accatccagg tactcgtatc
    56641 gttctaaaac acagtaatga tgaatttcca gttgtgggaa ttgctggtga ctcaggcttt
    56701 gtcagcatta acatgtcgaa atacctcatg aaccgtgagg ttggatttgg ccgcaaggtt
    56761 ctgcaaatcc tggaagaact taacatcggt tgggaacata tgccaacagg tatcgacgat
    56821 ctttctatca ttctccgttc tcgccaacta actcccatca aggaagaaga aatcctgcgt
    56881 cagttggttc aaaaggctaa agtagatcat gcagaaatcg aacacgacct ttctatcatt
    56941 atgattgttg gtgaaaaaat gaagagccac atcggagtga ctgctactgc gacacgcgct
    57001 ctatctgaaa acaaaatcaa catccagatg atgtctcaag gttctagtga agtttctatt
    57061 atgtttgttg tcaataaaga ccaagagaaa gcagcaatta aagccctcta caatgccttt
    57121 tttggagaaa gtaaggaaga ctaagcatgg cccaatcact taacaaaaca gtactcctca
    57181 gtacgacagg cacttcctac ctctctatcg ctgggaaagt tgggaaattc cttgtcggag
    57241 atcaggcttt ggaattttac ccagatgtca atgtcgaaca atttatccag attccttgga
    57301 gccatatcaa tcagattgga gccaatgtca ctggacgcaa aatcagccgc cacttcgaag
    57361 tctttacaga caaaggaaaa ttcctctttg cttcaaaaga ctcaggtgcc attctcaaaa
    57421 ttgcacgcga aaaactaggc aatgacaagg tcgtcaaact tccgaccctg attcagacaa
    57481 ttagccaaaa atttaaaaat ctatttgcaa aaaagtagaa actttagtat aatcatagca
    57541 acggataagt aggttatctt cttctttcag aaagtctgcg ggtactgcga gcagataggg
    57601 gggataggtg aaattctacc gttagtaaca attacataca caatcaagtg cacacctgtg
    57661 aagttggatg gaaccgtggc cctgccactc caacgttttg tcaggcgtgc ttttttcata
    57721 aaggagttct tatgttagat atcaaacgta ttcgtacaga ttttgaagct gtcgcagaaa
    57781 aattagctac acgtggtgta gaggctgctg tcttgaatga aatgaaagaa atcgatgcta
    57841 aacgtcgtaa catcttggtc aaggttgaaa ctctcaaagc agaacgtaac acagtttctg
    57901 ctgagattgc ccaagctaag cgcaacaagg aaaatacaga tgacaagatt gctgccatgc
    57961 aaaatctatc tgctgaggtt aaagccttgg atgctgaatt ggcagaaatc gatgctaaat
    58021 tgacagaatt tacaacgact cttccaaata tcccagctga cagcgttcct gttgggactg
    58081 acgaagacga caatgtggaa gttcgccgtt ggggtactcc acgcgagttt gacttcgaac
    58141 ctaaagctca ctgggatctc ggtgaagacc ttggtatcct tgactgggaa cgcggtggta
    58201 aggtaacagg cgctcgcttc ctcttctata aaggcctcgg tgctcgtttg gaacgtgcta
    58261 tctacaactt tatgttggat gaacatggaa aagaaggcta tactgaagtc atcacacctt
    58321 acatagtcaa ccatgattct atgtttggta ctggtcagta tccaaaattt aaggaagata
    58381 cttttgaact cagcgatacc aactttgtct tgattccaac tgctgaagtt cctctgacaa
    58441 actactaccg tgatgaaatc ttagacggca aagatcttcc aatctacttc actgccatga
    58501 gtccgtcatt ccgttctgag gctggttctg ccggtcgtga tacgcgtggc ttgatccgtt
    58561 tgcaccaatt ccacaaggtt gaaatggtca aatttgccaa accagaagaa tcttacgaag
    58621 aattggaaaa aatgacagcc aacgctgaaa acattcttca aaaactcaac cttccatacc
    58681 gtgtcgttgc tctctctact ggagatatgg gcttctcagc tgcgaagact tacgacttgg
    58741 aagtgtggat tccagcacaa aacaattacc gtgaaatctc aagctgttca aacacagaag
    58801 atttccaagc ccgtcgtgcc caaatccgtt accgtgatga agcagatggc aaggtgaaac
    58861 tccttcatac cttgaacggt tctggacttg cagttggacg tacagtggct gcaattcttg
    58921 aaaattacca aaatgaagat ggttctgtga ccatcccaga agcacttcgt ccatacatgg
    58981 gtggagctga agtcatcaaa ccataaaaaa taaggtttag ctatttctag ctagaccttt
    59041 tttcgtaacc aaatcagata agcacctagt acaaagaata aaatagttag gcatataatg
    59101 gtttcagcca ataccaggta atccagaaat ggaagtttca aaattccctg agccatcttg
    59161 agcgaggtcg ctgtgataat ggttgggaag gtgagggctg agaaggctgg ttgaaaacct
    59221 tgttttaaaa tgttgggcag acgagttaaa acaaagaaaa agaaggattg agaagccaaa
    59281 atcatgacaa tcaagaccca agtcggcagg ctggttcctc ctactcgaac tagagaagcc
    59341 aagagtagag agaaaggagc acagtagatt ccttcttgtc caagcaaggc tagtgggagt
    59401 ggatgtttct ttaaatcgct ataaataagg ggatagagat agaaggtcaa gagaaaacca
    59461 aaactcaagg tcgcataggc aatttcgata atacctacca gaggataggt caaggcagcc
    59521 actgctatcc ccacatagag aaccgtccaa cttggagtgg catgaaccct ccgccctgaa
    59581 caagcaaact tgatggtaaa accagcaatc aaggtcaaat ccaagagaaa tgaaaaccac
    59641 caaatccctt gtgctaccaa aggaagataa gagaatacgc gaaagacata ggtcgataaa
    59701 atcatcccag ccataggaaa ggttgccatt cctgacaaaa gagggggctt ggtcaattct
    59761 tgcttggttt ctttccaatt aaagagatgc agaattagaa agtaaatcca taaaaccaaa
    59821 ccagtcagac taaaaagatg ggatagaacc ggcaacgtat ctaaaataag atttccagct
    59881 cctgccaaac ctagcaaaca acctgaaaat actaagggga gttttttcat cctaacctcc
    59941 aataatcatg ttagtttcag tataacataa aagcgcttaa atgaggattt aaaaaaacga
    60001 agtccgctta tttcagactt cattttactc agatatgaat taggcataag gttgcaattc
    60061 tggattaatt ggtgtattag ctaagttgtt ggcatagtta cagaggattg ctaggctgac
    60121 accaaaaacc acatccaagg cattttgttg agtgtagcca gcttctaaaa actcagacaa
    60181 ggcttcatct cctacacgac ccttggtatt gataactgcc aaggtaaact tagctagggt
    60241 atccaattta ggatctgttt caattggagt acgattgcga agagcttgaa tcaagtcatc
    60301 attcatctgg atttgtttga tggaaaaggc tgtgtgacct gcgacacaga aggcacaacc
    60361 attggtcacg gctgccgtga tttgcaccac ttcacgctca acgggtgtca ggctgttgcg
    60421 acggtggata gatgagacaa tttggtaggc ttctaaaaca gtcggggcat tggccaagag
    60481 accgattagg ttgggaatat agccattgtt gtctttttct actgtttcaa gaatttcttt
    60541 cacttctgct ggtgctgact ctactgtatg gatagtaaat gttgtcataa gatacctctt
    60601 ttcttattat tgacactaat attattggaa aatcttataa aatcctgatt cctaagttta
    60661 tctaagataa agctttattc tctcataaga ttttcgttgt tatattagtt tatcacactt
    60721 ccaatcactt gcataatata tattatatat caggctgata aaaattattt ataggcaaaa
    60781 aaatcacacg agctgtgtga ttccattatt tgtcaaaata ctttttagtt tcagcaataa
    60841 cgactggcga caagaccaag agggcaatca agtttggcag agccatcaag gcgttaacga
    60901 tatctgcgat aatccagacc atatccaact cgataaatcc tcctaacaag accatgagca
    60961 caaaaaacac acggtagagc cagataaagc gagccccaaa gaggaactca aaacagcgtt
    61021 ctccgtaata gttccaacct agaatcgttg taaaggtaaa aagtacaagg aagatggtca
    61081 agagggcagg cccaaagtgt gaaaagactg ttgagaaagc tgactgagtc aaggcaaccc
    61141 cattcaagtc accactccaa actccagtta ccaagatggt caaaccagtt agagtacaaa
    61201 tgatgagggt atcaataaag gttcctgtca tggaaatcaa accttgctct actggttcat
    61261 ttgtcttggc agctgcagct gcaataggag cagaacccag accagattcg tttgagaaca
    61321 caccacgcgc cacaccattt tgaatagcca tccgaacgct agcaccagca aatccaccta
    61381 ccgcagcaag gggactaaaa gctgaggtaa agactaaagc gattgtgcca gggatttttc
    61441 cgatattaaa gaaaataact gtaagagttc ctaagatata aatgagggcc ataaaaggaa
    61501 caacagtagt tgaaacctta gaaatagact tgagtccacc aaagactgca atcgctacaa
    61561 agacagacaa gacgagagct gtgatggctg gcgaaatcgt cgttgtattt tggatagatt
    61621 ctgtaatcga gttgacttgg gtgaaggttc cgattcccaa gagagcaacc aatactcctg
    61681 ctactgcaaa caaaacagca agtggtcgcc acttttctcc catccctaga aggatatagt
    61741 gcatgggacc tcccgctact gcaccatggt cgtccttggt gcggtatttg atggccaaga
    61801 gtccttccgc atacttggta gccattccaa agaaagccgc catccacatc caaaatagag
    61861 ctcctggtcc accaaccttg atagccgtcg caactcctat gatatttcct gttccaacag
    61921 ttgatgccaa ggctgtacac agagctgcaa aactggatac atcaccatgt cccttatcct
    61981 ggataaaaat aagctgaaag gccttgggca gacgcaaaac ctgcaagagt cctagccgca
    62041 tggttaggta aatccctgtt ccgaccaata aaatcaagag gggcggtccc caagcaaaag
    62101 catcgattga tttaagcaat tctaacattt tcttctccta tcgtttcaac cccaaaagaa
    62161 agagcacatg caagatacat gtactctgga atgcttagat aaatgctaaa aagcggtcta
    62221 tcctagctct gtccttttac ctgagagttt gagcagttgc ctgccttgcc ccttcggtgc
    62281 ctttacggtc tctccagagt tccgtccatt tacagtcatg gaaaatcaaa cgattcccca
    62341 cttctattaa acttcattcg gtgttggtat ttaattgatt ctaattttac aaaaaatgtt
    62401 ggcttttgtc aatgtgttta ttagtaaaaa ttagttcaac agtttttact ttataaagtc
    62461 cagaatactg ctatccttta aaagtgacaa tagtcgcacc actgcctcca gcattttgtg
    62521 gggcatagcc gaaactcttg acatgtttgt ttctttgcaa gtatttggta actccttcac
    62581 ggatgactcc tgttccgata ccatggatga tatcaacttg agccatattg ttaagcaagg
    62641 cttggtcgat gaaggtatct agctcattca tggcttcttc atagcgcttg cctcgaagat
    62701 ccagtctagc ttgaggtcct cgcccagaag ttcgtttcac aacattgacc tgtttcttct
    62761 tgactggttt ttcttgctgg gcttgaacaa gatcaaactc tttctcttcc aaggtcatct
    62821 taatcaagcc aatttgggct tcccagcggc cgtccttgag ttgactggtc aaggtaccac
    62881 gctgaccata actgagaacc acgatatcat ctcccacctt tggagctcgt tttttcttgg
    62941 ccttttgaag gaccttgttt ttagacaagt ccactttttc aggagccaat tttttcaact
    63001 tggccttggc ttcaatgatt tcgtggggct tgagttggga tttactgtgg agatttttga
    63061 gaatctggtc actttcactt agggccatat ccacaatctc agcagcctgt tcacgcgcct
    63121 tgttaagctc ggtttccttt tcacgattaa gctcgttgta gagttttttt agcgcacggt
    63181 tcatcttgag attttcttgc tccacctcac ggatattgtc caagcgtttg cggctttcca
    63241 gcgtctgctc ttctaattgc tcaatgatac gattgacgtc attgtcctga tcgatctgct
    63301 gactggcatc tcctacgata acttcagata ggcctagacg tttggcaatt tcaaaggcat
    63361 tacttcggcc aggaacaccc tgcataaagc gataggtcgg gcgaagagtt gcagtatcaa
    63421 actccatact ggcattttgc acaaaggctg tctcaatacc gtaggccttg agttctggat
    63481 agtgggtcgt cgccatggtc ttgatttgac gcaggcgaag gtcctccaga atagccatgg
    63541 caagggctgc tccctcttgg ggatcagtac cagcccccaa ctcatccaaa agtaagagtg
    63601 aatgttggtt gaccttgcca agaatatcca cgatattggt catatggcta gagaaggtag
    63661 acaagctctg ctcaatagac tgctcatctc caatatcagc aaagatttct tcaaaaatac
    63721 caacacgact tcccttgtct gctaaaatcg gcaatcctga ctgggccatg acctgtgtca
    63781 agcccagagt tttaagcatg atggtcttcc cacctgtatt gggacctgta atgacaatag
    63841 ctgttaaatc ttgaccaaaa tagacatcat ttgcgacggc atttttgacc aaaggatggc
    63901 agacatggag cagttgaatc tcttgatttt ctgacagctg aggcacgact gcttgtcttt
    63961 cttgaataaa tcgaaccttg gcacgaatca agtccagatg accgataatc caagcgtcat
    64021 tagcaatctc agccgcatga gggcggacac gctcagaaat ttcttggaga atgcgaagca
    64081 tttcatagcg ctcatctgct cgcagactag caatttcttc gctcagtttg actacctcac
    64141 gtggttcgat atagacggtg tttccactag cagaaatatc atgaacgaca cctgcaatct
    64201 tattgcggta ggtgtttttg actggtaaaa cctgacggcc atttctgcta gcaacaattc
    64261 cttccgtcaa catctgccct ttttgcttga gcaagtcttg taaaacatcg cgtacctgac
    64321 tctcgctatc atgtattttt cgacggattc gcgccaattc ttcactggca aaattttcaa
    64381 tgaaacccgc atcattaaag gcctgaagat ttccttgtaa ttgcggaaaa tcatgtaatt
    64441 tctcaaacca aagggctaat tcttccaagc tgacattttc cagattggcg taaaaacttt
    64501 gaagttctcg gctggcaaga agcacgcgtt tcaagagtag gaactcctcg atattgagat
    64561 ccgctcccat ctccaacctc ttgcagactc ctgcaatttc cttagttgag agaatagtaa
    64621 aatgcggttg ctcgacgaaa agagcctgca tttctttcat ctcagcaaaa gcctgtttga
    64681 ttttatctgc tttggcagtc ggagccagct gtctcaattg ctccaagccc tgctcggtca
    64741 acaaatgagg ctcaaacaag gccttgacct tatcgaactc taatgtttct aatattttct
    64801 tattcatctt tatttccttg tctttgaatg tctaggtgtg gtagcttttt acattctgat
    64861 agattcgagt caaatctgta aacaaagggc taggaaaact cctgcccttt ttatccgatt
    64921 aaatttgtca cccagatttg tttgagccaa ctggttgtta tcggtatgct ctggatgatg
    64981 tgttttgcga cgatactctt ttcaagagga ttttgtataa ctgccatagg gatggtcgcc
    65041 aagattgtca aggccatttg caagacaaat aaggtcacca acatggacaa gatacctgct
    65101 gaaacttgga acaacttacc acccagtttt ttgctaggaa tcaagtgtaa gagaagacca
    65161 agcaaacgac caatgctata gacaatccca aatacaagca agtagccgat acctgcataa
    65221 aagaccttat ccagctgaaa gagttgatcc gatgggaaaa agaaagtccc ctgaccttcc
    65281 tgcgaatttg cataagggag caataaatgg aattgctctc caagcccctt ataaaactgg
    65341 ccagccataa aagccgatgc catggctgaa atcaggtaat aaacctgtaa gagcaggcct
    65401 ctccgatagc cgatataaaa tccccaaacc aagaccaata gaagaaggaa tgaaatcata
    65461 aggaatcctc aatcttgctc tgttcttgct tacaagtcac aagcttgtga cggagttctt
    65521 ctagctcttg ctccttatcg tcaaattcaa tctcacggct gagctgagtt gataaacagt
    65581 tgactgccaa caaaagagcg attgtttcat catctgcgct aggcatttgt tctttaattg
    65641 cttggtattt ttctgtcgca accttagcga tttcctccat aaaaaggtta tcatgttcgc
    65701 ttgtcaaggt taacgttttt ttcccgaatg taaatttgaa tcgatttaga tttgccataa
    65761 aattcacctc acgatattat accaaaattc gctaattttg tcagttttta caaattttac
    65821 tgcttttgtg gtacaataga aactatggca agtatcacac tcacaccaag cgaaaaggat
    65881 attcaggctt ttcttgaaca ctatcaaacc agtctggctc ctagcaagaa tccctatatc
    65941 cgctactttt tgaaactacc tcaagcaacg gtttctatct atacttctgg aaaaatcttg
    66001 cttcagggtg aaggggctga aaaatacgcc agtttctttg gctatcaagc tgtagagcaa
    66061 accagcggac aaaatcttcc tttaattggg acagatgagg tgggaaatgg ttcctacttt
    66121 ggtgggcttg cagttgtggc tgcctttgtc acacctgacc agcacgactt tttacgaaaa
    66181 ctcggtgtgg gggattctaa gactctgacc gaccaaaaga tccgtcagat tgctcctatt
    66241 ctcaaggaaa aaattcagca ccaggcactc cttctctcac ccagcaagta caacgaggtc
    66301 atcggagacc gctacaatgc tgtttcggtt aaggttgccc tccataatca ggctatctat
    66361 ctcctccttc aaaaaggtgt tcagcctgag aaaattgtga ttgatgcctt taccagtgct
    66421 aaaaattatg acaagtactt ggcacaagag gccaatcgtt tcagcaatcc tatcagctta
    66481 gaagaaaagg ctgagggcaa atacttggct gtcgcagttt cttctgtcat tgcgcgtgat
    66541 ctctttctgg aaaatcttga aaatctggga cgagaactgg gttatcagct cccaagtgga
    66601 gctggaacag cttctgacaa ggtggctagc cagattttgc aagcctatgg tatgcaggga
    66661 ctcagcttct gcgccaaatt gcactttaaa aacactgaaa aagcgaaaaa acgcttagaa
    66721 aggtaagtta tgaattcatt taaaaatttc ttaaaagagt ggggattgtt cctcctaatt
    66781 ctgtcattac tagctttaag tcgtatcttt ttttggagca atgttcgcgt agaaggacat
    66841 tccatggatc cgaccctagc ggatggcgaa attctcttcg ttgtaaaaca ccttcctatt
    66901 gaccgttttg atatcgtggt ggcccatgag gaagatggca ataaggacat cgtcaagcgc
    66961 gtgattggaa tgcctggcga caccattcgt tacgaaaatg ataaactcta catcaatgac
    67021 aaagaaacgg acgagcctta tctagcagac tatatcaaac gcttcaagga tgacaaactc
    67081 caaagcactt actcaggcaa gggctttgaa ggaaataaag gaactttctt tagaagtatc
    67141 gctcaaaaag cccaagcctt cacagttgat gtcaactaca acaccaactt tagctttact
    67201 gttccagaag gagaatacct tctcctcgga gatgaccgct tggtttcgag cgacagccgc
    67261 cacgtaggta ccttcaaagc aaaagatatc acaggggaag ctaaattccg cttctggcca
    67321 atcacccgta tcggaacatt ttaagaaacc taagaggccg agaatcacca atctcagcct
    67381 cttcttctat cgtgagaagt gattgtttat tgacaaatac tcaatgaaaa tcaaagaaca
    67441 aactaggaag ctagccgtag gctgcttaaa acagtgtttt gaggttgcag atggaagctg
    67501 acgtggtttg aagatatttt cgaagagtat aaaataaaaa caatcccaac tctcacctat
    67561 tcatgcaaag gaattttatg gaagtttatt tttcaggaac cattgaacgg attatttttg
    67621 aaaatcccag caatttttat cgcatcctcc tcctagaaat cgacgatacg gacgcagagg
    67681 attttgatga ctttgaaatc attgtcacag gaaccatggc tgatgtaatt gagggcgaag
    67741 actatacttt ttgggggcaa attgtccagc actccaagta tggagaacaa ctgcaaatca
    67801 gtcgttatga tcgcgcaaaa ccaactagta agggcttggt caagtacttt tcaagtagcc
    67861 atttcaaggg gattggtctc aagacagctc agaaaatcgt ggatacctat ggcgaaaata
    67921 ccattgacga aattttgcaa cacccagaaa agttagaagg catcgcagga ctctctgcca
    67981 aaaatcgcga ggctttcgtc tccactctcc gtctcaacta cggtacggag atggttttgg
    68041 ccaaactagc caactacggc attcccaaca aactagcctt tcagattcaa gacttttaca
    68101 aggaagaaac ccttgatgtg gttgaaaatt atccctacca actggttgag gatatcaagg
    68161 gtttgggctt taccattgct gaccaactag ctgaggaact aggcatcgaa agtcaggctc
    68221 ctgaacgctt ccgcgccggt ctagttcaca gtctttttca ggcctgtatg gaaacaggag
    68281 acacctatgt tgaagcacgg gatttgctgg aacaaaccct tactctcctt gagtcttccc
    68341 gtcccgtgga actagacccc agccaagttg cccaagagct ctcctacctg atcgaagaag
    68401 acaaggttca gcagattgat accaagatct ttgacaacag cctctttttc gctgaggaag
    68461 gcatccgcag tcacttggtt cgtatccttg aaaaaggaaa acagaagagt catgatttag
    68521 aaaccattca aaaacatatc actactatcg aggaagagct gggaattgag tatgataaca
    68581 ttcaaaaaca ggctatctgt gacgctatcc agaacaaggt ctttatcctg acaggtgggc
    68641 ctggtactgg taagacaact gttatcaatg gaatcatcgc tgtttatgcc cttttagaag
    68701 gacttgactt caggaagaaa aacaatctgc ccattcttct tgctgctcca actggacgag
    68761 ccgctcgccg catgaatgaa ttgacaggtt tgcctagcgc gaccatacac cgccacttgg
    68821 gaatgacagg tgacgatgat accagtcatc tggaagatta cctagatgct gactttatca
    68881 tcgtggatga attctctatg gtggatactt ggctggccaa tcaactcttc tccaatatct
    68941 cttctaacag taagatcctc atcgtgggtg acagtgatca gctaccttct gtcagtcctg
    69001 gacaggttct agcggatctg cttcatattc ctttgattcc tcagactcgc ttggaaaaaa
    69061 tttatcgaca aagcgaagaa tcaaccatcg tcaccctagc tagtcagatt cgacagggca
    69121 tcttgccagc tgatttcacc caaaaaaaag ctgaccgttc ctactttgaa attgctagtg
    69181 gccatattcc tgccactatt gaaaaaatct taggtgccgc cctcagaaat agtattcctg
    69241 cccgtgatat ccaagttctg gctcctatgt accgagggac ggcagggatt gatgctatca
    69301 atcagctcat gcaagacctg ctcaatcccc cacaaaaaga tcaactcagt tttgaagctc
    69361 ctcagtgcca ctatcgtaag ggagacaagg tcattcattt ggttaacgat gctgaaatca
    69421 atgtctttaa tggggattta ggagctatca cagacctgat tcctggtaaa tacaccgaat
    69481 cgaaacaaga cgagattgtc attgattttg atggtaatga agtctcttac ccccgtaacg
    69541 aatggtacaa gattcgcttg gcctatgcca tgagtattca taagtctcag ggaagtgagt
    69601 tcccagttgt catcctaccg attactagtg ctagccgacg tatgctggag cgaaatctca
    69661 tctacacagc cattacacgt gccaaaagca aactcatctt actaggcgaa ttacaagcct
    69721 tcgactatgc tacccaacac atcggaactg cccgaaaaac ctatctgatt gaacgcttca
    69781 gtgatctact ggagaatgtt gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa
    69841 gtgcctctga acaatcctac atcctaaccg aagaaaactg ggacagcatt ccagccatga
    69901 ttgggattac agacacagac ctcaaagaga tttttggaaa atagtgcatc agaaaaacca
    69961 ccaattcagg tgggttttct gtttattaag attattttac tgttgctgtg cttgtgatca
    70021 attcaacagc ttttttgata gtgatatcat gtttcaacat gtcagctgaa agcaagtttt
    70081 gaacttgtgc aacttccatg ttgtagtctg ctgccaattg ctcaacttct ttttggattt
    70141 cttcttctga agcatcaaat ccttcagctt tggcaactgc ttcgataaca aggttagtct
    70201 tagtacgtga ctcagcttct gcttggtatt ggttgtgaag gtcttcttga gtagttccag
    70261 tgatttggaa gtacatgtca gggttgatcc cttgacgttg caaattccca aggaattcat
    70321 ttactgaacg gtgaacttct tcatggatca tttcttctgg aagttctacg atttcagcat
    70381 tttctacagc tgtatcaatt gctgcacctt caactgcatc tttgtaagct tcttctttag
    70441 cagcagccaa ttctttgcgg tatttttctt tcaagtcagc aagtgtttca acttcttcat
    70501 caatgtcttt tgcaagttca tcgtcaagag ctggaacttc tttagctttt acttcgtgga
    70561 tagttgtcac gaatttagct tctttacctg caaggtcttc tgcttggtag tcttctggga
    70621 atgttacgat aacatcaacg gtttcgccag ctgagtgacc taccaattgg tcttcgaaac
    70681 cagggatgaa ttgacctgaa ccaagtccaa gtgagaagtt ttcacctttt ccaccgtcaa
    70741 attcaacacc gtcgatagaa ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag
    70801 cagcttcctt gataaccaat tcagccaggt tgttgcgttc gcgttcgata cgctcttcga
    70861 catcagcgtc agttacttct ttttctacat caactgatac ttcaaggttt ttgtagtcac
    70921 ccaattttac ttcaggtttt gtaacgactt cagcagtgat aacccagtct tgaccttttt
    70981 ccattgaagt tacgtcaatt tttggttggg caaccacttc aagaccagct tcttttacag
    71041 ctgcttcata agcgtttggc aaaagagcgt tcataacgtc ttggtaaagt gattcttcac
    71101 caaatttttg gtcgaagata ggacgtggaa ggtgaccttt acggaaacct ggaacattaa
    71161 gagatttctt cactgacttg aagacacggt ccaattctgg tttgatttgg tcttgagaga
    71221 tagtgaaagt caagacacca cggtttgttt ctttgttttc aaatgataca gacattctgt
    71281 catttctcct taaaattttt taaatacagt ctattataac attttctata aataaaatct
    71341 agactaatgc agccaattat agacaacaag cctttttcct aactaaaaca ctcataaagt
    71401 atagacaatt ttagactact ttggatatct tttggttagt cattttccaa aactaattta
    71461 tctaattttt cagttatata gta
//
LOCUS       DAVLAQ010000003        68032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000003 DAVLAQ010000000
VERSION     DAVLAQ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.003"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            524..1387
                     /locus_tag="VXB71_000157"
     CDS             524..1387
                     /locus_tag="VXB71_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0450338.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            1673..1873
                     /locus_tag="VXB71_000158"
     CDS             1673..1873
                     /locus_tag="VXB71_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0450339.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            1940..2605
                     /locus_tag="VXB71_000159"
     CDS             1940..2605
                     /locus_tag="VXB71_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0450340.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2677..3903
                     /locus_tag="VXB71_000160"
     CDS             2677..3903
                     /locus_tag="VXB71_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0450341.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4256..4330)
                     /locus_tag="VXB71_000161"
                     /pseudo
     CDS             complement(4256..4330)
                     /locus_tag="VXB71_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4401..5057
                     /locus_tag="VXB71_000162"
     CDS             4401..5057
                     /locus_tag="VXB71_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0450342.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            5047..5256
                     /locus_tag="VXB71_000163"
     CDS             5047..5256
                     /locus_tag="VXB71_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0450343.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSRVVTGKVGNLPQIK"
     gene            5474..6304
                     /locus_tag="VXB71_000164"
     CDS             5474..6304
                     /locus_tag="VXB71_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0450344.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            6458..7312
                     /locus_tag="VXB71_000165"
     CDS             6458..7312
                     /locus_tag="VXB71_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0450345.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            7412..8785
                     /locus_tag="VXB71_000166"
     CDS             7412..8785
                     /locus_tag="VXB71_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0450346.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            8778..9839
                     /locus_tag="VXB71_000167"
     CDS             8778..9839
                     /locus_tag="VXB71_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0450347.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            9841..10533
                     /locus_tag="VXB71_000168"
     CDS             9841..10533
                     /locus_tag="VXB71_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450348.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(10562..11131)
                     /locus_tag="VXB71_000169"
     CDS             complement(10562..11131)
                     /locus_tag="VXB71_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0450349.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11266..11880
                     /locus_tag="VXB71_000170"
     CDS             11266..11880
                     /locus_tag="VXB71_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0450350.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            11882..13528
                     /locus_tag="VXB71_000171"
     CDS             11882..13528
                     /locus_tag="VXB71_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0450351.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            13540..14826
                     /locus_tag="VXB71_000172"
     CDS             13540..14826
                     /locus_tag="VXB71_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450352.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            14878..15411
                     /locus_tag="VXB71_000173"
     CDS             14878..15411
                     /locus_tag="VXB71_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450353.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            15489..15959
                     /gene="nrdI"
                     /locus_tag="VXB71_000174"
     CDS             15489..15959
                     /gene="nrdI"
                     /locus_tag="VXB71_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0450354.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16252..17514)
                     /locus_tag="VXB71_000175"
     CDS             complement(16252..17514)
                     /locus_tag="VXB71_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0450355.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMATLPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(17824..18282)
                     /locus_tag="VXB71_000176"
     CDS             complement(17824..18282)
                     /locus_tag="VXB71_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0450356.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18279..18719)
                     /locus_tag="VXB71_000177"
     CDS             complement(18279..18719)
                     /locus_tag="VXB71_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450357.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19075..21024
                     /gene="mutL"
                     /locus_tag="VXB71_000178"
     CDS             19075..21024
                     /gene="mutL"
                     /locus_tag="VXB71_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0450358.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21349..21816)
                     /locus_tag="VXB71_000179"
     CDS             complement(21349..21816)
                     /locus_tag="VXB71_000179"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0450359.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(21817..23022)
                     /locus_tag="VXB71_000180"
     CDS             complement(21817..23022)
                     /locus_tag="VXB71_000180"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0450360.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23042..23677)
                     /gene="ribE"
                     /locus_tag="VXB71_000181"
     CDS             complement(23042..23677)
                     /gene="ribE"
                     /locus_tag="VXB71_000181"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0450361.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(23662..24762)
                     /gene="ribD"
                     /locus_tag="VXB71_000182"
     CDS             complement(23662..24762)
                     /gene="ribD"
                     /locus_tag="VXB71_000182"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0450362.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(24897..25011)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25168..25761
                     /gene="ruvA"
                     /locus_tag="VXB71_000183"
     CDS             25168..25761
                     /gene="ruvA"
                     /locus_tag="VXB71_000183"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0450363.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTARQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            25771..26334
                     /locus_tag="VXB71_000184"
     CDS             25771..26334
                     /locus_tag="VXB71_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0450364.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26331..27008
                     /locus_tag="VXB71_000185"
     CDS             26331..27008
                     /locus_tag="VXB71_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0450365.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27145..28176)
                     /locus_tag="VXB71_000186"
     CDS             complement(27145..28176)
                     /locus_tag="VXB71_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0450366.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(28431..29114)
                     /locus_tag="VXB71_000187"
     CDS             complement(28431..29114)
                     /locus_tag="VXB71_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0450367.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILTSMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29126..30070)
                     /locus_tag="VXB71_000188"
     CDS             complement(29126..30070)
                     /locus_tag="VXB71_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0450368.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30202..33033
                     /gene="uvrA"
                     /locus_tag="VXB71_000189"
     CDS             30202..33033
                     /gene="uvrA"
                     /locus_tag="VXB71_000189"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0450369.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            33026..34087
                     /locus_tag="VXB71_000190"
     CDS             33026..34087
                     /locus_tag="VXB71_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0450370.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34219..34617
                     /gene="spx"
                     /locus_tag="VXB71_000191"
     CDS             34219..34617
                     /gene="spx"
                     /locus_tag="VXB71_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0450371.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            34683..35252
                     /locus_tag="VXB71_000192"
     CDS             34683..35252
                     /locus_tag="VXB71_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0450372.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35339..35605
                     /locus_tag="VXB71_000193"
     CDS             35339..35605
                     /locus_tag="VXB71_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0450373.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            35609..36028
                     /gene="ruvX"
                     /locus_tag="VXB71_000194"
     CDS             35609..36028
                     /gene="ruvX"
                     /locus_tag="VXB71_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0450374.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            36044..36349
                     /locus_tag="VXB71_000195"
     CDS             36044..36349
                     /locus_tag="VXB71_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0450375.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            36607..37857
                     /locus_tag="VXB71_000196"
     CDS             36607..37857
                     /locus_tag="VXB71_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0450376.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            37854..38396
                     /locus_tag="VXB71_000197"
     CDS             37854..38396
                     /locus_tag="VXB71_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0450377.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            38542..40074
                     /gene="cls"
                     /locus_tag="VXB71_000198"
     CDS             38542..40074
                     /gene="cls"
                     /locus_tag="VXB71_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0450378.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            40332..41870
                     /locus_tag="VXB71_000199"
     CDS             40332..41870
                     /locus_tag="VXB71_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0450379.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            41990..44197
                     /gene="nrdD"
                     /locus_tag="VXB71_000200"
     CDS             41990..44197
                     /gene="nrdD"
                     /locus_tag="VXB71_000200"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0450380.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44209..44349
                     /locus_tag="VXB71_000201"
     CDS             44209..44349
                     /locus_tag="VXB71_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450381.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            44393..44899
                     /locus_tag="VXB71_000202"
     CDS             44393..44899
                     /locus_tag="VXB71_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450382.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            44892..45482
                     /gene="nrdG"
                     /locus_tag="VXB71_000203"
     CDS             44892..45482
                     /gene="nrdG"
                     /locus_tag="VXB71_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0450383.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            45490..46107
                     /locus_tag="VXB71_000204"
     CDS             45490..46107
                     /locus_tag="VXB71_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0450384.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            46373..46681
                     /gene="rpsJ"
                     /locus_tag="VXB71_000205"
     CDS             46373..46681
                     /gene="rpsJ"
                     /locus_tag="VXB71_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0450385.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            46898..47524
                     /gene="rplC"
                     /locus_tag="VXB71_000206"
     CDS             46898..47524
                     /gene="rplC"
                     /locus_tag="VXB71_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0450386.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            47549..48172
                     /gene="rplD"
                     /locus_tag="VXB71_000207"
     CDS             47549..48172
                     /gene="rplD"
                     /locus_tag="VXB71_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0450387.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48172..48468
                     /locus_tag="VXB71_000208"
     CDS             48172..48468
                     /locus_tag="VXB71_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0450388.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            48486..49319
                     /gene="rplB"
                     /locus_tag="VXB71_000209"
     CDS             48486..49319
                     /gene="rplB"
                     /locus_tag="VXB71_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0450389.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            49423..49704
                     /gene="rpsS"
                     /locus_tag="VXB71_000210"
     CDS             49423..49704
                     /gene="rpsS"
                     /locus_tag="VXB71_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0450390.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            49716..50060
                     /gene="rplV"
                     /locus_tag="VXB71_000211"
     CDS             49716..50060
                     /gene="rplV"
                     /locus_tag="VXB71_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0450391.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            50073..50726
                     /gene="rpsC"
                     /locus_tag="VXB71_000212"
     CDS             50073..50726
                     /gene="rpsC"
                     /locus_tag="VXB71_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0450392.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            50730..51143
                     /gene="rplP"
                     /locus_tag="VXB71_000213"
     CDS             50730..51143
                     /gene="rplP"
                     /locus_tag="VXB71_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0450393.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            51153..51359
                     /locus_tag="VXB71_000214"
     CDS             51153..51359
                     /locus_tag="VXB71_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0450394.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            51384..51644
                     /gene="rpsQ"
                     /locus_tag="VXB71_000215"
     CDS             51384..51644
                     /gene="rpsQ"
                     /locus_tag="VXB71_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0450395.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            51670..52038
                     /gene="rplN"
                     /locus_tag="VXB71_000216"
     CDS             51670..52038
                     /gene="rplN"
                     /locus_tag="VXB71_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0450396.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            52116..52421
                     /gene="rplX"
                     /locus_tag="VXB71_000217"
     CDS             52116..52421
                     /gene="rplX"
                     /locus_tag="VXB71_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0450397.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            52445..52987
                     /gene="rplE"
                     /locus_tag="VXB71_000218"
     CDS             52445..52987
                     /gene="rplE"
                     /locus_tag="VXB71_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0450398.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            53005..53274
                     /gene="rpsN"
                     /locus_tag="VXB71_000219"
     CDS             53005..53274
                     /gene="rpsN"
                     /locus_tag="VXB71_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0450399.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            53559..53957
                     /gene="rpsH"
                     /locus_tag="VXB71_000220"
     CDS             53559..53957
                     /gene="rpsH"
                     /locus_tag="VXB71_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0450400.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            54149..54685
                     /gene="rplF"
                     /locus_tag="VXB71_000221"
     CDS             54149..54685
                     /gene="rplF"
                     /locus_tag="VXB71_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0450401.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            54769..55125
                     /gene="rplR"
                     /locus_tag="VXB71_000222"
     CDS             54769..55125
                     /gene="rplR"
                     /locus_tag="VXB71_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0450402.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            55143..55637
                     /gene="rpsE"
                     /locus_tag="VXB71_000223"
     CDS             55143..55637
                     /gene="rpsE"
                     /locus_tag="VXB71_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0450403.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            55609..55833
                     /gene="rpmD"
                     /locus_tag="VXB71_000224"
     CDS             55609..55833
                     /gene="rpmD"
                     /locus_tag="VXB71_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0450404.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            55978..56418
                     /gene="rplO"
                     /locus_tag="VXB71_000225"
     CDS             55978..56418
                     /gene="rplO"
                     /locus_tag="VXB71_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0450405.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            56431..57741
                     /gene="secY"
                     /locus_tag="VXB71_000226"
     CDS             56431..57741
                     /gene="secY"
                     /locus_tag="VXB71_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0450406.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            57892..58530
                     /locus_tag="VXB71_000227"
     CDS             57892..58530
                     /locus_tag="VXB71_000227"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0450407.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            58647..58865
                     /gene="infA"
                     /locus_tag="VXB71_000228"
     CDS             58647..58865
                     /gene="infA"
                     /locus_tag="VXB71_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0450408.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            58890..59006
                     /gene="rpmJ"
                     /locus_tag="VXB71_000229"
     CDS             58890..59006
                     /gene="rpmJ"
                     /locus_tag="VXB71_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0450409.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            59024..59389
                     /gene="rpsM"
                     /locus_tag="VXB71_000230"
     CDS             59024..59389
                     /gene="rpsM"
                     /locus_tag="VXB71_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0450410.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            59407..59790
                     /gene="rpsK"
                     /locus_tag="VXB71_000231"
     CDS             59407..59790
                     /gene="rpsK"
                     /locus_tag="VXB71_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0450411.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            59833..60768
                     /locus_tag="VXB71_000232"
     CDS             59833..60768
                     /locus_tag="VXB71_000232"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0450412.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            60780..61166
                     /gene="rplQ"
                     /locus_tag="VXB71_000233"
     CDS             60780..61166
                     /gene="rplQ"
                     /locus_tag="VXB71_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0450413.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            61431..61697
                     /locus_tag="VXB71_000234"
     CDS             61431..61697
                     /locus_tag="VXB71_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0450414.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            61707..63044
                     /locus_tag="VXB71_000235"
     CDS             61707..63044
                     /locus_tag="VXB71_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0450415.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            63288..63980
                     /locus_tag="VXB71_000236"
     CDS             63288..63980
                     /locus_tag="VXB71_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0450416.1"
                     /translation="MVKVRLYLIRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(64083..65719)
                     /locus_tag="VXB71_000237"
                     /pseudo
     CDS             complement(64083..65719)
                     /locus_tag="VXB71_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(65709..66737)
                     /locus_tag="VXB71_000238"
     CDS             complement(65709..66737)
                     /locus_tag="VXB71_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450417.1"
                     /translation="MNITIPKGSLFTLLGPSGCGKTTLLRMIAGFNSIKDGEFYFDDT
                     KINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLKQKKVPKEELIQQTNKYLELMQI
                     AQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEPLSNLEAKLRLDMRQAIREIQH
                     EVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNI
                     IPANLEKRSDGAYIVFSDGYALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISD
                     SVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKDNRIRLRINTQKLNIFSADGSQNL
                     IKGVNHGM"
     gene            complement(66812..67918)
                     /locus_tag="VXB71_000239"
                     /pseudo
     CDS             complement(66812..67918)
                     /locus_tag="VXB71_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        20298 a        12740 c        14906 g        20088 t
ORIGIN      
        1 taatttttga aaagaatttt gaactattta caaaacaaag tgatctaatt gttgcaaata
       61 gatgggatag gggccttgaa gcttataaag ataaagttta cacaaggggg atctggataa
      121 gagattaact attgatatta aaaaggcaat aatttataaa atttgtacaa aaaaatgtta
      181 aattttcaca ttttcatagt atactgttta atagaaagta ggttctttgt aaccgctcca
      241 ttataaaatc ctttcactct tccggtatac tattaggaaa aacataactg gaggatattt
      301 tgagctcaca cctcatcgtt ccagtggctg ttccccaagc tcgtgtactg cccaaaaaag
      361 ttagacattc tatttagaac gaggattgag ttctgtattg tacaaggctc ggtcctttta
      421 gagtcagctt aaggctggct tttttatttt ttctaactat cagaatattt tgacaaatga
      481 acacaaataa tgatataata tgcaaaagct aggaggtggt aggatgattg aaaaaatgga
      541 attgggggaa ttttacaagg aattacgttt ggcgagaaag ctcaagcagt cagatgtggc
      601 ttgtgacggg ctaacagctt ctcagttgtc caagtttgag ctagggcagt ccatgttgtc
      661 tgctgataag ctcatattag ccatccaagg gatcaatgtg acctttgatg agtttgggca
      721 caagctcaac aactatcaag aatctccaca tatgcagatt ggtagaaagg ttgtggatcg
      781 ctttgctcat caagatatag ctggcttaga gcaactgttg gaggaagtcg agcaagaaca
      841 gatggcagag acttatcgtc gtttgaatgc tattgtaatc aaagatgcca tccactcact
      901 agataaaagc tacccactag cagaggagga tagcgagttt ttgaccacct atctctatgc
      961 tatcgagtct tggacctggt ttgaactcta tctcttttgc aatactctgc ccttcttgag
     1021 caatcaagat ctgatctttt tatcaacctc cttactcgaa aaatccaaag aatttaaaga
     1081 gttagtacac aatcgattgt atatgaagca aggactctta aatatcatct cagagctcat
     1141 ggagcgcaaa cttttttctt atatcccaat ctttgaagcc gagctggaga gtatgctccg
     1201 tccatacgat gtttttgaga aagtgttgtg gcagttttta aagaagatga gcattttcct
     1261 tcaaactaag ggaagcaatc aaaaagagat tgaacacttt atccaatctc tgcaagtatt
     1321 agaaaatcca caattaatag ccctttttga attgcgtttg cagcaataca aaaagcttat
     1381 cgattagtta gaaatggcaa aataataata atctcagcaa cgattttcaa taatgttaaa
     1441 atttgtttct tcatatttct ccactcctca ttagtagtaa ctttattata ccagagaagt
     1501 aatcaaattc accaaaatcg caaatctgaa atttctataa gaaaaaatat caaatatgcg
     1561 attttctaaa ataagccaat tttcgtgtta tactgtactt gtaaagcact tgaagcaaat
     1621 cctaggtcgc agaagtggtt tacaaatgaa gataattgaa ggagtgtaaa agatgttaaa
     1681 tttacaattt gcagaaacaa tggaattgac agaagctgag ttggagatag tttatggagg
     1741 ggaatttggg aataatgctg ttatcccagc cggtgcttgg ggagggttcg ggacaccttg
     1801 gtcaatcact aatttctgga agaaaaattt taacgataga cctgactttg attctgaccg
     1861 ccgtcgttat taatatccaa agcccttgcc ttttcttggg taggggctgt ctttatttca
     1921 tagtatagga ggaaatagaa tgaaaaagat aatctcacac cgctacttta ttatagtttt
     1981 tctactagtt attgctgacc agaagttcag tgttctagtt ttacgcagcg accttgttac
     2041 tgggctatct gactttgcct attatctgtc ggatatgatg ttgaattttc ttgtggtttt
     2101 atttgctctt attgctatga tttggtcggg gaaatggcag aaaatcaata gtagaaagtt
     2161 taaaggatcc tatcttttct attccttcct agctctgctt gcttttgttg tttggaattt
     2221 cgttaccttt tttcttttcc cacctactcg aaatgaaatt tcttatcaac atgctgctcc
     2281 gacttttaca ggggctacag catttttgat gtattttttc tatcctgtga ttgcaggtcc
     2341 catttttgaa gagataatcc atcggggatt ggtgatgaca gctctggaaa aaggaaagaa
     2401 atgggggcta gatgtacttg gctctgctat tttatttggg gtctcgcaca ttagtaatca
     2461 cggttgggtc ttgacagact ttgtcttcta tatgggtgga ggtcttatat ttgcagtctt
     2521 atttagaatg acaaagtcaa tttattggcc tattggactg catatagtct acaatggtat
     2581 tggtcagctt ttgatgttac tgtaattttg gttgttagta gtatcgcggt ctattcttgg
     2641 ggaaagattc ccatttgaac ttaagaagga gttgtaatga aagtatttct tcaaaataga
     2701 gattttaggc aattaactat caaccagtgg atttcaacgc ttggggatac gattttttat
     2761 ctggccttcc tgaattatgt ggcagatgcg tcttttgccc ctttggcgat tttacttatc
     2821 acgatttcag aaacccttcc ccaagttcta caaatctttc tgggagtttt ggcggatttt
     2881 caacatcatc gtgtcttgaa atacacagtc attagtttta caaaattttt gctttactct
     2941 atagtgtccc tatcgctttc agggcagtct ttttccttgt tgctagtaac ctttatttgt
     3001 atgattaacc tcttgtctga cacattgagt tatttttcag gcgccatgct cactccgatt
     3061 ttcattagaa ttattgggca agatcatctg gcagaagcta ttggatttaa acagtcaact
     3121 gttagtttag tgaaaacaat cagtaatatc ctaggaggag tcttactagg tattctatcc
     3181 atccagttta tttccttact gaacgctctt acctttttaa tcgcattttt aggtatcctc
     3241 ttcataaaaa ctgacctctt gaaagtagaa aaaacgatta gctatcaaga aggactctct
     3301 gtaaaatcct tttgccagca tttgctccaa tcatcgaaat tgatatggaa tatgaataag
     3361 gtgctcttgg ttttgtttat tatctctact agtcaagcag tgataaatgt tacagttcct
     3421 gtctctactc tatttttgag gaatcaaccc tttttgaatt tacaaacagg tcaatctctt
     3481 gccttgctat ccacttttga actgtcagcc ctgattgtcg gaagccttgt aagtggctat
     3541 ctgcaacata ccatttccat aaaaacagct ctctatgcct cacttgtcat ccagttgctt
     3601 cttctagtag gatttgccac agttcgtttt gactggattc tcatctttag taccttggat
     3661 gcctttttcg caggtgttct ctctcctaga ttgcaagaac tcgtctttaa acaaatacct
     3721 gaggagtcaa tgggagcagt tcaatcttct atcagtgcca ttacggttgt tttacctagc
     3781 ttatttacaa tatctttggt aaccattgct actagctttg gaactctggc agttagcttt
     3841 gttttattgc tatttcttct agttgccttt gttatgcttc tgaatattcg tgaaagtatt
     3901 tagtggagaa tttctataat atatgtttga gactggattg ccagtctttt tatgatggtc
     3961 aaaatcaaca gactttttct cttttctgaa tgtgttatag tagactgaat ctaaaatagt
     4021 acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgttct
     4081 catcttattt caatctgcta tataatagtc catgctgtgg ctggattctt ttcagcctac
     4141 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta tatgtgttac
     4201 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact tcatcagttc
     4261 tatctgcaac ctcaaaacag tgttttgagc aacctgcggc tagtttccta gtttgctctt
     4321 tgattttcat tgagtattat taagacaata tgaggagaaa gatgaaagaa aaaggatttt
     4381 aggagggggc gcaggcagcc atgccaacgg ctcttggcta tgtcagtatc ggcctggcct
     4441 gtggaattat cggtgcgccc tatgtgacac ctgttgagat gggcttgatg agtctctttg
     4501 tttatgctgg gagtgcccag tttgccatgt tggcactgat tgtggttcaa gctcctgtgg
     4561 cagctattgc tatgacggtt tttctaatca atttgcgtct ctttttgttg agcttacacg
     4621 catcgactta tttccgtcat accagtcttt ggcacaatat cggtatgtct agtatcttga
     4681 cagatgagac ctatggcgtt ttgatgggcg aattagccca tacagataag gtcaatccga
     4741 tgtggatgca cgggaacaat ctcaacagct atgtggcttg gtttgtggga acagtggtcg
     4801 gaacggctct aggtgacctg ttgccaaatc cagaaatctt tggtttagat tttgccctgg
     4861 ttgggatgtt tatcgggatt tttgcttcgc aattccagat gatgcaaaga cggatttctg
     4921 tccgcaatct gctcattatc ttagcagttg ttgcagtgtc cttcttttta cttttgacag
     4981 tggtgtctca gtcactagct gttctgtttg cgacgctact tggttgtagc atggggatgg
     5041 ttttagatgg tcagtaagta tcttttatta gcagttattt tctctggtct tgtgacctgg
     5101 attccccgta tgattccctt catcttggtc aagtataagg gcctgcctac gattgttgag
     5161 cgttttttga agtttttgcc tgtttccatt atctttgcct tgattctttc aagagtagtg
     5221 acaggtaagg ttgggaacct tcctcaaatc aaatgactgg acttcttagc agtctttcca
     5281 acagcttggg tagcttttcg ctaccgcaat ctagtcggta cggttctctt tggagtagtc
     5341 ttgattgccg tcttgcgttt ggtcttttaa ataagtcata aagaaaactt atcacagaga
     5401 tagatatcat ataatggcgt aattactttt tttctgataa gattataagg tattctattt
     5461 tggaggaaat gacatgaaaa aaatcgttaa atactcatct cttgcagccc ttgctcttgt
     5521 tgctgcaggt gtgcttgcgg cttgctcagg tggtgctaag aaagaaggac aagcagctag
     5581 caagaaagaa atcatcgttg caaccaatgg atcaccaagg ccatttatct atgaagaaaa
     5641 tggcgaattg actggttacg agattgaagt cgttcgcgct atctttaaag attctgacaa
     5701 atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc tttgctggtc ttgacgctga
     5761 ccgttacaat atggctgtca acaatcttag ctacactaaa gaacgtgcgg agaaatacct
     5821 ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc gtgaagaaag atgactctag
     5881 tatcaagtct ctcgatgata tcggtggaaa atcgacggaa gtcgttcaag ccactacatc
     5941 agctaagcag ttagaagcat acaacgctga acacacggac aacccaacta tccttaacta
     6001 tactaaggca gatttccaac aaatcatggt acgtttgagc gatggacaat ttgactataa
     6061 gatttttgat aaaatcggtg ttgaaacagt gatcaagaac caaggtttgg acaacttgaa
     6121 agttatcgaa cttccaagcg accaacaacc gtacgtttac ccacttcttg ctcagggtca
     6181 agatgagttg aaatcgtttg tagacaaacg catcaaagaa ctttataaag atggaactct
     6241 tgaaaaattg tctaaacaat tcttcggaga cacttatcta ccggcagaag ctgatattaa
     6301 ataatttctt gaaatcatcc attctgagta agatgggtgg tttctcagtt tttagggata
     6361 tagttttaaa ctatatatct gactatctaa taacaatttg tgaaatcaaa caaattgtga
     6421 gatactagta cggtattatt tttaaggaga aagaatcatg aaaatcaaaa aatggcttgg
     6481 tctagcagcc cttgctacag tcgcaggttt ggctcttgca gcttgcggaa actcagaaaa
     6541 gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt aaccgtagcg gttctgaaga
     6601 aaaacgttgg gacaaaatcc aagaattggt taaaaaagac ggaattacct tggaatttac
     6661 agagttcaca gactactcac aaccaaacaa agcaactgct gatggcgaag tagatttgaa
     6721 cgctttccaa cactataact tcttgaataa ctggaacaaa gaaaacggaa aagatcttgt
     6781 agcgattgca gatacttaca tctctccaat ccgcctttac tcaggtttga atggaagtgc
     6841 caacaagtac actaaagtag aagacatccc agcaaacgga gaaatcgctg taccaaatga
     6901 cgctacaaac gaaagccgtg cgctttactt gcttcaatca gctggcttga ttaaattgga
     6961 tgtttctgga actgctcttg caacagttgc caacatcaaa gaaaatccaa agaacttgaa
     7021 aatcactgaa ttggacgcta gccaaacagc tcgttcattg tcatcagttg acgctgccgt
     7081 tgtaaacaat accttcgtta cagaagcaaa attggactac aagaaagcac ttttcaaaga
     7141 acaagctgat gaaaactcaa aacaatggta caacatcatt gttgcgaaaa aagattggga
     7201 aacatcacct aaggctgatg ctatcaagaa agtaatcgca gcttaccaca cagatgacgt
     7261 gaaaaaagtt atcgaagaat catcagatgg tttggatcaa ccagtttggt aataagaaac
     7321 agggaggtgg gagagaaaat tccacctctt gcttttgtat agagtataga ttgtaaagaa
     7381 gactattcgt tcatagaaag gtagagagaa tatggttttt cctagcgaac aagaacagat
     7441 tgaaaaattt gaaaaggatc atgtagtcca acattatttt gaggttttgc gtaccttgat
     7501 ttctaagaaa tcagtctttg cccagcaggt tggactcaag gaagtcgcaa attatctggg
     7561 tgagattttc aagcgtgttg gagctgaagt ggagattgat gagagctata cagcgccctt
     7621 tgtcatggca catttcaaga gttcgcgtcc agatgccaag accttgattt tctataacca
     7681 ctatgacact gtgccagcgg atggggatca ggtctggaca gaggatcctt ttacgctttc
     7741 ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac gacaagggtc atatcacagc
     7801 tcgcttgagt gctttgagaa aatatatgca gcaccatgat gatttacctg tcaatatcag
     7861 ctttatcatg gagggagcgg aggaatcggc ttcaacagac ctagataagt atttggaaaa
     7921 gcatgcagac aaactccgtg gggcggattt gttggtctgg gaacaaggga ccaaaaatgc
     7981 cttggagcag ctggaaattt ctggtggcaa taaggggatt gtgacctttg atgccaaggt
     8041 aaaaagcgct gatgtggata tccactcgag ttatggtggt gttgtggaat cagctccttg
     8101 gtatctcctc caagccttac agtctcttcg tgctgcggat ggccgtatct tggttgaagg
     8161 cttgtacgaa gaagtacaag agcccaatga acgagaaatg gccttgctag aaacttatgg
     8221 tcaacgaaac ccagaggaag ttagtcggat ttatggattg gagttgcctc tcttacagga
     8281 ggagcggatg gcctttctaa aacgtttctt tttcgagcca gcgcttaata tcgaaggaat
     8341 ccagtctggt tatcaaggtc agggtgttaa gactatttta cctgcagaag ccagtgccaa
     8401 gctagaggtt cgtctggttc cgggcctaga accgcatgat gttctggaaa aaattcggaa
     8461 acagctagac aaaaatggct ttgataaggt agaattatac tataccttgg gagagatgag
     8521 ctatcgaagc gatatgagcg caccagccat tctcaatgtg atcgagttgg ccaagaaatt
     8581 ctatccacag ggcgtttcag tcttgccgac gacagcgggg acaggaccta tgcatacggt
     8641 ctttgatgcc ctagaggtac caatggttgc attcggtcta ggaaatgcca atagccgaga
     8701 ccacggtgga gatgaaaatg tgcgaatcgc tgattatcac acccatatcg aattagtaga
     8761 ggagctgatt agaagctatg agtagagata ttatcaagtt agatcagatc gatgtgactt
     8821 ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt gaccattcac atccaagaag
     8881 gggatatcta cggaatcgtt ggatattctg gagcaggaaa atcaaccctt gtacgggtga
     8941 ttaatctctt gcaaaaacca tctgcaggga aaattaccat tgacgacgat gtgatttttg
     9001 acggcaaggt gaccttgacg gcagagcagt tgcgtcgtaa acgtcaagat atcggaatga
     9061 ttttccagca ttttaacctg atgagccaaa agacagcaga ggagaatgta gcctttgccc
     9121 ttaaacactc tgaactcagc aaggaagaaa agaaggctaa agtagctaag ttgttggact
     9181 tggttggttt ggcagatcgt gctgaaaact acccttcaca actatctgga gggcaaaaac
     9241 agcgtgtggc aattgcgcgt gccttggcca atgatccaaa aatcttgatt tcagacgagt
     9301 caacttctgc ccttgatccg aagacaacca agcagatttt ggccttgttg caagatttga
     9361 accaaaaatt aggcttgact gttgtcttga ttacgcatga aatgcagatt gtcaaagaca
     9421 ttgccaaccg tgtggcggtt atgcaggatg ggcatttgat tgaagagggt agtgtgcttg
     9481 aaatcttctc agaccctaaa caacctttga ctcaagactt tatctcaaca gctacaggta
     9541 ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt ggaacacttg tctgaaaaca
     9601 gtctcttggt gcaactcaag tacgctggat cttcaacaga cgagccactt ttgaatgaat
     9661 tgtacaagca ttatcaagta atggctaata ttctctatgg gaatatcgaa atcctcgatg
     9721 gtactcctgt tggagaattg gtggtggtct tgtcaggtga aaaagcagcg ttggcaggtg
     9781 cccaagaagc cattcgtcaa gcaggcgtac agttaaaagt attgaaggga ggacagtaag
     9841 atggaatcat tgattcaaac ctatttgcca aatgtctata agatgggttg gtctggtcag
     9901 gcaggctggg gaacagctat ctacctaacc ctctatatga cagttctttc cttcattatc
     9961 ggaggcttct tggggctagt ggcaggtctc tttctcgtct tgacagcgcc aggtggtgtc
    10021 ttggagaata aagtcgtatt ctggatttta gacaaaatta cctcaatttt tcgtgcgatt
    10081 ccctttatca tcctcttggc aatcttgtca ccactttctc acttgattgt taaaacaagt
    10141 atcgggccaa atgcagccct tgtcccactt tcttttgcag tctttgcctt ctttgcccgt
    10201 caggtgcagg ttgtcttggc tgaattggat ggcggtgtca ttgaggcggc tcaagcgagc
    10261 ggagcgactt tctgggacat cgtgggtgtt tacctatcag aaggtcttcc agatttgatc
    10321 cgtgtgacga ctgtgacctt gatttccctt gttggggaaa cagctatggc cggtgcggtt
    10381 ggagctggtg gtatcggtaa cgtagccatc gcttatggat ttaaccgcta caatcacgat
    10441 gtgaccatct tggcaaccat tattatcatt ttgattatct ttgcaatcca attcttggga
    10501 gatttcttga ctaagaaatt gagtcataaa taaaaagagc cgcgtggctc tttttaactg
    10561 atcagatttt ctgtgcaaat tttttactca aggcttgtcc aatcaaggca cccactaggg
    10621 ctccgatgac aatacttgcg ataaatagaa ggacagttcc agggtttgga gcgaccatga
    10681 tacggtcgat atattcttgg gattttcctc ttgccagaag agtagccata taggctttgg
    10741 gcgcaatcca cataagcaag attggtcctg ttgtactaaa ggcgaaaata atgaaagaaa
    10801 ggaagttctt tgttttgtcc ttgtattttc ctaaatgagc tacttcatct gctaggaggc
    10861 cacagataat tccaggaagg aaggaaccag caccgtgttt agttcccaag aaaaagaggg
    10921 caatgacaag gccgatagtg gtaatggctc caaagcgcgg aacttttgcg actaggatca
    10981 tatagacgct accgccgaca agggcagtaa aggcaggcgc ataaaacatg tttccagttt
    11041 ggtcaaagag attgcccaaa aggacaccaa tccccatgca gaggaagtaa agaactgcaa
    11101 aaagcagtgt agttaagata gatttcttca tgaattgtct cctgataatt ttttcacaat
    11161 tctcattgta ccacggtttg gtgggattgt aaatggatac tagaagtttt tgaaaacgct
    11221 tgaaatatga tataatggtt tcatagttat ttttagggga atatcatggg tagattttta
    11281 gactttgtct ttaatcgttt ctttttaggg atgattgcga cagccttctt ttggctatta
    11341 actttagcag gagggattat ccttggtcta gcgccggcta gtgccacctt gatgagctta
    11401 tatgcagaac atggttatag ctttcgggaa tacagtttga aggaggcttg gtctctttac
    11461 aagcaaaatt ttgtctcaag caacctgatt ttctatagct ttttaggtgt gggtctagtt
    11521 ttgacctatg gtttgtatct cttggtgcaa ttgcctcatc agaccattgt tcatttgatt
    11581 gcgacccttt tgaatgtcct agtagttgcc ctgatctttt tggcttatac agtatcttta
    11641 aaattacaag tttattttgc cttgtcctat cgaaatagtc tcaaattatc cttgattggc
    11701 atctttatga gtctagcagc tgtggccaag attctccttg ggactgtgct acttgtagca
    11761 attggttact atatgcctgc cctgctattt tttgtaggaa ttgggatgtg gcatttcttt
    11821 atcagtgata tgttggaacc tgtctatgaa atcatccatg aaaaattggc gacaaaatag
    11881 aatgaagcag ttttggctac atacgcttct aagaacctat agttcagtga tgatcattat
    11941 cattgcgagt tttgcaatct tactctctta cgctgactgg gattcacgtg aaaaggaagc
    12001 ccagagagta gcccagcgtg taactgctag aacagtgagt gaaattgaat attaccatag
    12061 agagtcaacc cagatagctc aggctttagt tgaaaaccaa gctcgtattg agggaatcta
    12121 taaatacttt agtcttagca tgccagacta tttttactgg caattagagc ggaaagcttc
    12181 gccttatata tcagtctctc tgtatgaaaa tgttgatgac ctctatgttc gaaatgattt
    12241 tgtaactgga gtggccattg cttttcaaga ttacaaggaa gtctatgttt ctactaaaga
    12301 caaacgtagt ggagaaaaaa tcagggctga ggatttcaaa ccagcaggaa atagttttgc
    12361 cattccggtg tcagatccag tgtcagatca agatttagga gtgatttaca tctccttgga
    12421 tcctgctgtt ttataccatg ccattgataa tactagaggt catactccga tggcagtaac
    12481 agtgacctca ccttttgata cggagatttt tcatattggt gagacagttg ataaggagag
    12541 tgaaaattgg ctagttggct taacttctca tggatatcag gttcaggtgg cagttcctaa
    12601 aaactttgtt ttacaaggaa cagtgactag ctctgctttg attgtgggtt tgagccttct
    12661 ctttattgtc attctttatc tgactttgag gcagactttt gctaattacc aaaagcaggt
    12721 agtggattta gtagaatcca ttcaagtcat tgctcaaggc gaagaggggc gtcggattga
    12781 catttccgag aaagatcagg aattactcct aatcgcggag acgaccaatg atatgttgga
    12841 tcgattggaa aagaatatcc atgatattta ccagttagag cttagtcaaa aagatgccaa
    12901 tatgcgagcc ttgcaggcgc aaatcaatcc tcattttatg tataatacgc tggagttctt
    12961 gcgcatgtat gcagttatgc agagtcaaga tgagttggca gatatcattt atgaattcag
    13021 tagtctcttg cgtaacaata tttccgacga aagagagacc ctcctcaaac aggaattaga
    13081 attttgccgt aaatacagct atctctgcat ggttcgctat cccaagtcca ttgcctatgg
    13141 tttcaagata gatccagagt tagagaatat gaagattccc aagtttacct tgcaaccgct
    13201 ggtagaaaac tatttcgcgc atggtgttga ccacaggcgg acagataatg tgattagcat
    13261 caaggctctt aaacaggatg gttttgtgga aattttggtg gtcgataatg gtagaggaat
    13321 gtcggctgaa aagttggcaa atatccgaga aaaattaagt cagagatatt ttgaacacca
    13381 agccagctac agtgatcaaa ggcagtctat cgggattgtc aatgtacacg agcgttttgt
    13441 gctctatttt ggagaccgct atgccattac tatagagtct gcagagcaag ccggtgttca
    13501 gtatcgtatt acaattcaag atgagtagaa agggagaaaa tgtataaagt attattagta
    13561 gatgatgagt acatggtgac agaaggtctg aagcgtttga ttccctttga taagtgggat
    13621 atggaggttg tcgcaacagc cagtcatgcc gatgaagctc tagaatatgt tcaggaaaat
    13681 cctgtcgatg tcatcatttc cgatgtcaat atgccagaca aaacagggct tgatatgatt
    13741 cgggagatga aagagatctt accagatgct gcctatatcc tgctctcagg ttatcaggag
    13801 tttgattatg taaaaagagc aatgaacctt agtgtggtgg actatttggt caagcctgtt
    13861 gataaggtag agctgggaaa tctgctggag aagattgcag gtcagctcgg cgagagaggg
    13921 aagaaaagtc agactcttag tcaagaatta gacgaggctg gatttgttag ttatttaggg
    13981 gataaggaga attggtggat aggtctatcc aaggaaaaac aaggttcctt caccattccc
    14041 tactatgtct tgggccaaga ctggcagatt ttcatttctg gccaacctct agatggttta
    14101 gtcgttacac cttttgaagc tccttatcaa gaacactttg aacgctggaa gctgaatgct
    14161 gagaaaaccc tcttttacgg ttctgtaaat ttgcagcagt ctgagagtct ctttgcctat
    14221 tacgaaccga tttatagggt tatcattcag ggaaatctca atcaaatcgt agaagagtta
    14281 aatctcttgg agaaggtagt tcttgaaaat acgccgcgtg ttccgattac taaacagctt
    14341 tttattcagt ttgtcatgga tgttttccat ttatttgaac atctcaaagc tgatgacctg
    14401 acagacatcg tcaaaaccat tcatgctatt caatccttcg atgaattggt ttcttatatc
    14461 aaggaaactc tgatcagctt tttcggtcaa taccgtatga atgaaaatgt ggtcagtgtg
    14521 ctggaagtca ttggtcgtga ttaccaaaaa gagctttccc tcaaggatat cagtaaggct
    14581 ctctttatca atcctgttta tctagggcag ttgattaagc gtgaaaccga ttcgactttt
    14641 gcagagttac taaacaaaca acgtattaag gctgcccaac aacttttgct ttcaactagt
    14701 gacagcatcg aagatatttg ttatgctgtt ggttacagta accttggata tttctataaa
    14761 gttttccgaa aattgtgcgg aaaatcgcca aaagcctacc gaaaacaggt agaaactata
    14821 ctataagatt tgtattcctt tacaaaaggt gctataatat tatcaggagg ttctatcatg
    14881 aaaaagaaac caatttatct atgggtcttg ctaatcttgt ctgcccttat ttcagttccg
    14941 tctctgtttg gaattgtgag tcccttgcct agtaaagaag cccttcgtgc tgctcagaaa
    15001 caagttgcag gggtcaatgc tcagcaatta gaagaccagc ttaattatac ctatagagta
    15061 gcagaagcat ctcattctat ttttaatgtt gctttgattg tgctatctac tattttagtg
    15121 gtcgtagcga ttgtcttcct tgttcgtaaa aatttgcaat atgcaaacta tacttacgtt
    15181 ggctatgttt tgttagctat tattggttcg atttatggct atgttggttt acaagacgct
    15241 gtgcagttgg ttcaagatga gagcatgcgt ttgacagtga gtattggttc aaaagctgtt
    15301 agcattttct atatcgtcat caatgttctc ttcctagccc ttgtcttcta taagatgtgg
    15361 cgacaacaga aagccttggc agaagaagag gaaacagaag agcttaccta agtattgaca
    15421 aaaaagaact atcaagatac aatcttggta gttgtttttt gattatagat aaaatcatgg
    15481 aggtacatat gaagacaatt tctttagttt atattagttt gagtggcaac actgaaagtt
    15541 ttgtgacgcg cttgaaagac tatctcttgt cccagtacaa agggattgag gttcaaaaga
    15601 ttcatatcaa ggatttggtc aaggaaggca aaaatttcta tgaaatggac catccctatg
    15661 tcgctttttt gccgacctat ctcgaaggtg ggaatggcgt ggataacgga gatgttgaga
    15721 ttttgacgac accggtggga gattttattg cctatggtaa caatgctagt aagtgttttg
    15781 gtgtggttgg gtcaggaaat cgtaacttta ataaccaata ctgcctaaca gccaagcaat
    15841 acagtcaacg ctttggcttc cctgtattgg ctgactttga aatgcgaggc atgctggaag
    15901 atatcaaaca tgtcgcagct attatcgcag atttgtatga gttggaaaag gagaattaat
    15961 actcaatgaa aatcaaagag caaactagga agctagtcgc aggttgctca aagcacagct
    16021 ttgaggttgc agatagagct gacgtggttt gaagagattc tcgaatagta taaagttctt
    16081 ataagatgtg gttgaagttg ttcaactgtt ttttgagtat aaacagtctt taagaacgta
    16141 aaaaagcata agttcaggtc ttcaaaacct tgttcttatg ctttttatca tagaaatatt
    16201 tgctgaattt tctcttgaaa tgaaacctta tcttcatctc gcgcttgtcc cttaccctgc
    16261 ttttccgatt gcgagtgcgt agataaagaa gatggcgaag ccaaagagga aaatcaatcc
    16321 cgcaatggca aggtgtttga gccaagaagg aagatttttg ttttcacgtg ttaccaaggc
    16381 gtaattcaaa agagcaaaga aaggtgttgt caggaaagag ccaatcatgg caaagcggag
    16441 catggttgaa acctgaccag cgaagaactt gataatgacg ataccgatga tagcagtgat
    16501 ggtcatccag atgttcaaag atttacgatt gtcctctttt tgactgatta gcagtcggag
    16561 agattcctga ttaacgcgag aatagccatc gataacagtt ataactgttc caaagataca
    16621 gaggaaggca ataaaggtaa tcaagtaacg ggaccattcg ccaagaacag aggcatacat
    16681 gcccacgaat tgagagatgt atttggctga agcagcttca accgcctgcc ctgtaggata
    16741 ctgaatcagt gctcccagtg ccacaaagaa gacggctagg atagctgttc caatataacc
    16801 agtgttaaag tcaaacagag cgtcttctgt gttaaagttg acggtctttc tcttttcagc
    16861 tgaccaaagt gaattgatgg ctgaaatttc aataggagcc ggcatccatc ctaggaggga
    16921 gacgatgaag ggcagagttg ccatttgcca aggtgtcttc tcgacaaaat cagaactgta
    16981 ttctggatgc ttgaccgccg caatgataac tgcaagaaca gtcgcaatgg ttaaggcaga
    17041 cataatccat ttgaccatgc cgtctaaaag tttgtagcct ccaaagagta gcatagccca
    17101 aatgattgca acgagaatga gggaccactg agtaatgcta agtccaatca ttgggaaggc
    17161 actggcgatg atagctgagc acagaatggc aacaccagcc gtgttgacca tagccgaaaa
    17221 gacattgaga ataaagaaaa tccagagata gagttttcct ttttcggcat aaccttcaac
    17281 caaagtcttt ccagtatcag ctgtgtattc agcaccaaaa cggaaaaatg gatatttaaa
    17341 gacattggct aagatgacca agagaagtag agaccaaccg taagaaccgc cagcttgagt
    17401 tgaggataca atgtgggaac ctccaacagc ggcagttgcc attaggattc caggtcccat
    17461 tgcttttagc ttgcttgccc aggttgattg atttaaggaa atagcttgcg acatgataaa
    17521 tactcctttt tgaattttca gaataatctg tatatgcaat ctatattcta caaaaaattt
    17581 tggaaaaatg caagaatatt ttgaaaaaag atagaaaatt tacaaagaaa atctgaaata
    17641 actgttatga tatagcagat tgaaactaga atagtacact tttgcttcta aaacattgtt
    17701 agaaatcgat ttgactgtcc tgattgattt atcctgttct tatttcattt cactatagta
    17761 aggtgcagca ggataaagca aaaccgagaa gtttctttct cggttttgct tattatgagg
    17821 ttcctatttt ctatgctcca agagttgatt gatgtgatct acttttttag cctctctttt
    17881 atagagaata gcccagatga tgagatagac aatcgcaaac tcgataatga gctggaggta
    17941 gaaaatccag tggaagggga accaaccagc aagagttgct agtgggacaa agccagccag
    18001 cataaggaag aaatgagtca gagtggcacg aagcatgctc cagtcacggc tgaataagcg
    18061 gttgccaaag ttgaagagca taccgatggc tgcccagata agtgtgcagt agagcaagac
    18121 cagggcaccg tgaacctgat gctgatccat cacttggccg atgagagagt agggatttag
    18181 tggtgcgtag gtatttggtg cataaatgag tgaaaagagg atggagagga tgaggccgat
    18241 aagaacaccg gcagctgcat cgtgaaatac ttgttttttc atagttctaa tttctccttg
    18301 atggttttta gataacggcg tgaagagtag gtgaagcttt cgtttttcaa gaaaatttct
    18361 accagaccgt ttggcgtgag cttgaggtga gagatggaat cgatattgat gatttctgat
    18421 tgggaaattt ggataaaatt gcttggcaag agtttaagaa cctgatagag tcgcaaatca
    18481 atgctgtagg tctgactcgc ggtttctgct agaaccttcc gattctcgat atagaagcgc
    18541 tgaatcttgc caatctcaac tagatagacc tgatcatcga tttttccttt gattttttct
    18601 ctttggtcca gattttctgc gaactcgatg actttctgga ctttttcggt ttcttgaggt
    18661 gcttggacaa tcagcttttc ctcctcgtaa gtctcactaa tctgtagttc tactttcata
    18721 aatttctctc cttgtttttc atacaaaatt aatctcactt cttgtacacc tttattaata
    18781 ctcttcaaaa atctcttcaa accacgtcag cgtcgtcttg ccgtaggata gttgttgact
    18841 ttgtcagttt tatctacaac ctcaaaacag tgttttgagc tgtctgcgtc tagctttcta
    18901 gtttgctctt tgatttttat tgagtatacc actattttac tccctctggc aagggacttt
    18961 gtctatgtgg agggattggg ctcctatgtg gtggagtttt tctgttcttt ctgaaatatg
    19021 gtataatagc actaattaat ttctaggaaa atagatacag aaaggggctg aaagatgtct
    19081 catattattg aattgccaga gatgctggca aaccaaatcg cagctgggga ggtcattgaa
    19141 cgtcctgcca gtgtggttaa agagttggta gaaaatgcca ttgacgcggg ctctagtcag
    19201 attatcattg agattgagga agctggtctc aagaaggttc aaatcacgga taacggtcat
    19261 ggaattgccc acgatgaggt ggagttggcc ctgcgtcgcc atgcgaccag taagataaaa
    19321 aatcaagcag atctctttcg gattcggacg cttggttttc gtggtgaagc cttgccttct
    19381 attgcgtctg ttagtgtctt gactctgtta acggcggtgg atggtgctag tcatggaacc
    19441 aagttagtcg cgcgtggggg tgaagttgag gaagtcatcc cagcgactag tcctgtggga
    19501 accaaggttt gtgtggagga tctctttttc aacacgcctg cccgtctcaa gtatatgaag
    19561 agccagcaag cggagttgtc tcatatcatt gatattgtca accgtctggg cttggcccat
    19621 cctgagattt cttttagctt gattagtgat ggcaaggaaa tgacgcggac agcagggact
    19681 ggtcaattgc gccaagcaat cgcagggatt tacggtttgg tcagtgccaa gaagatgatt
    19741 gaaattgaga actctgacct agatttcgaa atttcaggtt ttgtgtcttt acctgagttg
    19801 actcgggcta accgcaatta tatcagcctc ttcatcaatg gccgttatat caagaacttc
    19861 ctgctcaatc gtgctatttt ggatggtttc ggaagcaagc ttatggttgg acgttttcca
    19921 ctggctgtca ttcacatcca tatcgaccct tatctagcgg atgtcaatgt gcatccaact
    19981 aagcaagagg tgcggatttc caaggaaaaa gaactgatga ccctggtttc agaagctatt
    20041 gcaaatagtc tcaaggaaca aaccttgatt ccagatgcct tggaaaatct tgccaaatcg
    20101 accgtgcgca atcgtgagaa ggtggagcaa actattctcc cactcaaaga aaatacgctc
    20161 tactatgaga aaactgagcc gtcaagacct agtcaaactg aagtagctga ttatcaggta
    20221 gaattgactg atgaagggca ggatttgacc ctgtttgcca aggaaacctt ggaccgattg
    20281 accaagccag caaaactgca ttttgcagag agaaagcctg ctaactacga ccagctagac
    20341 catccagagt tagatcttgc tagcatcgat aaggcttatg acaaactgga gcgagaagaa
    20401 gcatccagct tcccagagtt ggagtttttc ggacaaatgc acgggactta tctctttgcc
    20461 caagggcgag atggacttta catcatagat cagcacgctg ctcaggaacg ggtcaagtac
    20521 gaggagtacc gtgaaagcat tggcaatgtt gaccagagtc agcagcaact cctagtgccc
    20581 tatatctttg aatttcctgc ggatgatgcc ctgcgtctca aggaaagaat gcctctctta
    20641 gaggaagtgg gcgtctttct agcagagtac ggagaaaatc aatttattct acgtgaacat
    20701 cctatttgga tggcagaaga agagattgaa tcaggcatct atgagatgtg cgacatgctc
    20761 cttttgacca aggaagtttc tatcaagaaa taccgagcag agctggctat catgatgtct
    20821 tgcaagcgat ctatcaaggc caatcatcgt attgatgatc attcagctag acaactcctc
    20881 tatcagcttt ctcaatgtga caatccctat aactgtcctc acggacgtcc tgttttggtg
    20941 cattttacca agtcggatat ggaaaagatg ttccgacgta ttcaggaaaa tcacaccagt
    21001 ctccgtgagt tggggaaata ttaaaagtat aaaaaagtct gggaaaaatt ttcaaaatca
    21061 gaaaaacgca taaaatcagg tgttcaaaaa ccttgatttt atgcgtttta tcatggaaat
    21121 agttacttca tgttttccta attcttttcg aaactctttt taaaccacgt cagttttatc
    21181 agtaatctca aaacagtgtt ttgagctaat tttgccagtt ttgtctgtaa catcgaagtt
    21241 gtgttttacc actctgcgac tggtttccta gtttgctcta tgattttcac agagtattaa
    21301 attgcgattt tgccaagttt ctttattcgt ctaaaagtag agtctgttct atgcgtctaa
    21361 tgtacgaatt aggttgacca tttcaatagc tccttgtgca cactcagaac ccttatttcc
    21421 tgctttggta ccagctcgtt ctatggcttg ttcaattgta tctgtcgtta gcacaccaaa
    21481 cataacagga atttcgctat ttaaactgat ttgggcgatt cccttagata cctcgctaca
    21541 tacataatca taatgacttg tattccctct aatgacagct cccaagcaga taattgcatc
    21601 atatttttta ctttttgcca tttttgatgc aatcagtggt atttcaaaag ctcctggaac
    21661 ccaggctacc tctatatctt tctcgtttac attctctctt ttgagattat ctagtgctcc
    21721 agataataat tttgaagtta taaattcatt aaatctcgct acaacaatac ctattttaat
    21781 attgtttgct actaaattac cttcataagt gttcatttat ttttcctcca tatttaaaat
    21841 gtgacccatt cgatttttct ttgtttctaa ataaaaacta tcgtaaggat tggcttctat
    21901 ttcgattgat attctactgg aaatggtaat tccatatttt tctaactgtt caaccttgtc
    21961 aggattattt gtcagtaaat gaagtgactg aagtcccaga tctttaagca tttgtgctcc
    22021 aatatgatat tctcttaaat caccttcaaa gcctaatgca agattggcat caagcgtatc
    22081 catgccttga tcttgtaaat gataggcttt taatttattg ataagtccaa ttcctcgtcc
    22141 ctcctgtcgc aagtaaagta agacacccga accattctca acaatcattt tcatagcttt
    22201 atcgaattgc tgtccacaat cgcaacgtaa agagcctaaa acatctcctg ttaaacattc
    22261 ggagtggacc cgacataata cattggcttc atcctctatg tttcccataa taagagcaag
    22321 atgatgttcc ccatttagtt tatctatata gctaattgct ttgaaattac cgtatctagt
    22381 aggcatattg acagttgaaa ctcgttctat cagctgatca tatacttttc tatattcttg
    22441 taattctttg atggtaatta gtggaatgtt gtgtttcttc gagaactgaa ttaaatcatc
    22501 tgttctcatc attttgccat catgattcat tatttcacaa cataggccac actcttttag
    22561 tccagctaat tttaataaat caacagttgc ttctgtgtgt ccatttcttt ctagaacacc
    22621 accttttttt gcaattaaag gaaacatgtg tcctggcctg cgaaaatcag agggtgttat
    22681 atcttcagct acacacatac gtgcggtcag tcctctttcc tcggcagaaa tacctgtggt
    22741 cgtttcttta taatcaattg aaactgtaaa agcagtctta tgattatctg tattgttttc
    22801 aaccataggt gaaagcatta attgattagc taaactttcg ctcataggca tacaaattaa
    22861 tcctttggca taagtagcca taaaattaac attttctgtt gtagctgctt gtgcagaaca
    22921 aattaagtct ccttcatttt ctctatcctt gtcgtctata acaagaacaa gtcgtccctt
    22981 ctgcaatgct tctaatgttt cttgtatttt tcgatattcc attgactgat tatcctttct
    23041 gctaaaatcc attttgatat aatagttcct tagatatttc tgattttgga gagttatcca
    23101 tcagtttttg cacatattta cctaagatat cattttcaag atttactgta ctcccgactt
    23161 gtttactttt aagaatggtt tgtttcaagg tatgagggat aacagatact gaaaagttta
    23221 ctttggagac tttagcgaca gtcagactaa tgccgtcaat tgtaatagat cctttttcaa
    23281 ctattaaatc taaaatttct ttttgtgtgt tgatttgata ccatacagca ttatcatctt
    23341 tttttattga cgagattttt cctgtaccat caatgtgtcc tgtaacgacg tgacccccaa
    23401 gtcgaccgtt gatagataag gctctttcta gattcacctc acttccatgt tttaatagag
    23461 taagagctgt tcgactccat gtttcattca ttacatcaac tgtaaaggat tgatgattga
    23521 aatgagtaac tgtaagacag ataccattta ctgctatact atcgcctaaa tggatatccg
    23581 ttaatatttt tgaggcttta attgatagtt tacaattacg agagtctttc tgtattcttt
    23641 caacttttcc gatttcttca attattcctg tgaacatgga taaatcactt cactttctat
    23701 gagatagtca tttcctattt gagaaaaagc ataaggtttc aatctaatag cgtcatttgg
    23761 caaagaaatg ccttcacctc cgacaggaaa cttggcactg cctccaaaaa tttttggtgc
    23821 aatatatatt ttcagctcat caacaatttg ttgttccaaa gcactccaat tcattagact
    23881 gcccccttct agaactaggc tatcaatctg catgtttcct agatgttgca ttaaactcga
    23941 taagtctata tgattgcctt ttttctttat ggaaagtatt tcacagccat gattttgata
    24001 tagcttcatt ttatttttgt cttcagagga agtggcaatg taagttttaa tatcatttgc
    24061 tgtttttacg attttagagg taagaggagt tcgtaaatgt gtatcgcata tgatacggat
    24121 aggatttttc ccttcctcca atctacatgt cagcaaagga tcgtcttgaa taacagtatt
    24181 gactcccacc ataattgcac taacatggtg tcgtaactga tgcacatgct ttcttgcttc
    24241 ttcttcagta atccatttgg attgatttgt tttagtggct atttttccat ccattgacat
    24301 tgcatatttc ataaaaacat agggtacatg ctgggtaata tactttctaa aactttttat
    24361 taagttaaga cactcatttt ctaaaattcc aacagtaact tgaagattat tttcctcaag
    24421 tatctttact ccttttccag atacaatagg attacagtct aggcttccaa tgactactct
    24481 tgtaatacca ctatcgatta tagcatctat acagggaggt gttttcccga agtgacaaca
    24541 gggttcaagt gttacataaa gcgtcgctcc gacaggggat tctctacagt ttttaagagc
    24601 atttctctca gcatgtgggc caccaaaaaa ctcatgataa ccttgtccga tgatgtgatt
    24661 atcttttaca ataactgcgc cgaccatagg attgggattg acgtaaccag cccctttttg
    24721 tgccagtttt attgctaatt tcatatattt tgaatcgctc atctcactac ctccaaaaaa
    24781 aatatacctt gaatagggga ctactcaagg catacaaaag aaaacttatg cgattaacaa
    24841 aaatactctg aaatgacaag taatcatttc agagcacgca aaaagcacaa atatactttt
    24901 atcttctttc atccagacta tactgtcggc tttggaattt caccaaatca tgcctttcgg
    24961 ctcgtgggct ataccaccgg tagggaatta caccctgccc tgaagatagt tattcaatta
    25021 cagatgatta tagtacttaa ttttgaatat gtcaacagat aaataccgat tgtttttgat
    25081 atactgtatt tgtgataatc gattctcgct cctcggataa agaaaatatg atatactaga
    25141 taaacgaaat aagagagaag gaatactatg tacgcatatt taaaaggaat cattaccaaa
    25201 attactgcca aatacattgt tcttgaaacc aatggtattg gttatatcct gcatgtggcc
    25261 aatccttatg cctattcagg tcaggttaat caggaggatc agatttatgt gcatcaggtt
    25321 gtgcgtgagg acgcccattt gctttatgga tttcgctcag aggatgagaa aaagctcttt
    25381 cttagtctga tttcggtctc tgggattggt cctgtatcag ctcttgctat tatcgctgct
    25441 gatgacaatg ctggcttggt tcaagccatt gaaaccaaga acatcaccta cttgaccaag
    25501 ttccctaaaa ttggcaagaa aacagcccgg cagatggtgc tggacttgga aggcaaggta
    25561 gtagttgcag gagatgacct tcctgccaag gtcgcagtgc aagcaagtgc tgaaaaccaa
    25621 gaattggaag aagctatgga agccatgttg gctctgggct acaaggcaac agagctcaag
    25681 aaaatcaaga aattctttga aggaacgaca gatacagctg agaactatat caagtcggcc
    25741 cttaaaatgt tggtcaaata ggagcagaga atgacaaaac gttgttcgtg ggtcaagatg
    25801 acaaacccgc tctacatcgc ctatcatgat gaggagtggg gtcagcccct ccatgatgac
    25861 caagcattgt ttgagttgtt gtgtatggaa acctatcagg caggcctgtc ttgggaaacg
    25921 gtactcaaca aacgccaagc tttccgagaa gcctttcata gctatcaaat tcactcagtc
    25981 gcagagatga ctgagactga attggaagcc atgctggaga atccagctat cattcgaaat
    26041 agagccaagc tttttgctac acgcgctaac gcccaagtcc ttctacagtt acaggcagag
    26101 tacggctctt ttgatgccta tctttggtct tttgttgagg ggaaaattgt cgttaacgat
    26161 gttcctgatt atcgccaagc gccagctaaa acacccttat ctgagaaatt agccaaagat
    26221 ctcaaaaaac gaggcttcaa gttcacaggc ccagtcgccg tattgtcttt tctacaggct
    26281 gcagggctag ttgatgacca cgagaatgat tgtgagtgga aaggtcttaa atgatgtcta
    26341 acaaaaataa gggaattctg atttttgcga ttctctatac agtcctcttt gtgtttgatg
    26401 gcgttaaatt gctggcttct ttaatgccat ctgtcattgc aaattatctt gtttatgtag
    26461 ttttagcttt atatggctcc ttcttgttca aggatagatt gatccaacaa tggaaggaga
    26521 ttagaaagac taaaagaaaa ttcttctttg gcgtcttaac aggatggctc tttctcattc
    26581 tgatgactgt tgtctttgaa tttgtatcag agatgttgaa gcagtttgtg agactagatg
    26641 gacaaggtct aaatcagtct aatattcaaa gtacctttca agaacaacca ctactgatag
    26701 ctgtttttgc ttgtgtcatt ggacctctgg tagaagaatt atttttccgt caggtcttat
    26761 tgcattactt gcaggaacgg ttgccaggtt tactaagcat tattctggta ggacttgttt
    26821 ttgctctgac tcatatgcac agtttggccc tatcagagtg gattggtgca gttggttact
    26881 taggtggagg ccttgccttt tctattattt atgtgaaaga aaaagagaat atctactatc
    26941 ccctacttgt tcacatgtta agcaacagcc tctccttaat cattttagct atcagtatag
    27001 taaaatgaaa tgagaacagg acaaatcgat ttctaacaat gttttagaag tagaggtgta
    27061 ctattctagt ttcaatatac tgtaatatgt gatgaaaatg ccagtaatga taccgagaaa
    27121 aaagctgaga aacttttccc agctttattt gttatagtca aagagaatga cttgttcctg
    27181 tgcatctaca tgagcatgga ccccaaaggg tacaattgct cttggagttg cgtggccgac
    27241 attcagatta tagacaatcg ggatattgct gtcaatgata tccaatagtg cctctttata
    27301 gtcgtcatgg aaagtttcat ccataggttt tccgaccaag agtccattga tgaccgcgaa
    27361 tatgccagtg tcctttaaag ttagcaacat ctttttgaag tcttctggct taggcttttc
    27421 ttcgcttgtt tcgagcaaga ggattttccc ttcccagtct gacaagtcag ggaaaagttt
    27481 gtatttttgg cagagttccg tgctatctgc gtatcgagag ttgtcaaaga tatcgtagag
    27541 ggattcgagg caaccaccga ggattttccc ctcgaactgg gcacttcctt gcaacaagtc
    27601 aaaacctgta tttgtatgac tgacacgagg tgttcccagg gccgtgggac taaaatcagt
    27661 tcgttcctca taccaaacgt cactagggcg gatttctgaa attcttcccg tctcaatcaa
    27721 ttctttaaag tagtgaaggc tataggctag catttctttg tctaattcac aaatgtctgc
    27781 taaaaaggat tgaccataaa aagtcttgat tcctaattta tgcaacatga ggtggttcat
    27841 ggttgtatcc gagaagccaa gaaaaatttt ttgtttgata accttttgga gttggtcatt
    27901 ttcaaaaaga taaggtagca agcgataggt atcgtctcca ccgatggcac ataggatcat
    27961 gtcgatgcta tcatcagaaa aggcatgaat caaatcctct gcacgagctt caggatggtc
    28021 cttgataaag tctaatcctt ttaacgaatg gggcaaaaag atgggattga gtcccagatc
    28081 cttgagacgt tggataccca agtccacttc gtgtttgaca aaatcctctc cgataatgcc
    28141 actagataaa ctaacaatac caatagtaga aaccatatct catcctccta gaaatagatt
    28201 gagcctattt tatcacaaaa tataagagaa agctatgtgg gatttcagaa gaatactttt
    28261 aatactcttc gaaaatctct tcaaaccacg tcagttttat ttgcaacctc aaagctgtgc
    28321 tttgagcaac ctgcagctag cttcctagtt tgctctttga ttttcattga gtataactca
    28381 aaaaagtaag tgaaaaagca accgcacctg cagttgcttt tatcgttttc ttattcttga
    28441 tagcgtgttg gtcctgcact tgcactacgg atattcaagc gtttcttgag atagaagcga
    28501 agggctagga gggctactcc aataatagct agtggcaatg gatccagtac tgggttaagg
    28561 ctagctggta ggaagcttgt tgcaaagaag acaagcaacc aaaggaacat agaagttagg
    28621 ataactagta cagatttcca gaaaggtgga cgttgactgc gatccatatc tggtccatag
    28681 tattggtaaa caaagtagta catcaagtag aaggcaaatc caccaaccag tccaactaat
    28741 agaagagtaa tcaatccata gccgaaagct tgatctgccg caaagaaggt tgtgagggcg
    28801 ctgacaaggg caaagaggct agtgatgaaa agagctgagt ccataatcat cagttttgga
    28861 tcatcatttt cttttggatg ctctttttcg tactgctctt tgacagtgaa gctatgagcc
    28921 caatgagttg gtgcgccgta tagggaacgg gcagttgtac ctttagattg ctcctcaagg
    28981 atttggggaa tgacttcctc aaaaatagtc tggatttcag cgtctgtttt cccatctttg
    29041 atgaattgtt gggtagcaat gtggacaaac tcttggtttt tcttagttaa tttttgtaga
    29101 tcaatttgag acataggaac tcctcttaga accatttttt atggatgaga tagagagtga
    29161 gcgagacact catagcaaag gcgataaaga cgattaacca gaaggcattt ggctctccgt
    29221 ttaggggaat ttcattatcc ttaaagttca tcccgtaggc agaaaagacc atggttggga
    29281 tggacatgac gatggtcaca agggccaagg ttttcatgat gttgttctgg ttgttagaaa
    29341 tgatagaggc aaaggtctct gtcatagaat gcaagacgtt tccataaata tctgccatct
    29401 cgatggcctg ttgggtttca atcagggtgt cttcaagcag gtcttcgtcc tcaaggtatt
    29461 tcttgatatt gctggttgaa ctggtcaatt tcttaatcac gcgctcattt gttttgaggg
    29521 aggccttgaa atagacgata gttttttcca attccatgag ctcaatcaat tcttcattac
    29581 gagttgattg atgcagttga ctttcgattt gttcactctt gcggtcgatt gaacgaaggg
    29641 ctgttaggta aagctctgca ttgcgataaa gaatttgaaa gataaaacgt gaacgcatga
    29701 aggtatagaa attacgcaat cgacggttga taaagacatc aaggacaggt agtggttcca
    29761 aacacgtagt gataatggtt tcctcagtga tgataatacc aagcgggatg gttacgtagt
    29821 aggtgcggtt atttctttcc tccgtgaccg gcacgtctac gataatcagg gtatactcgt
    29881 cttcaatggt aatacgagac atttcttccg catcgagcgg tgctcgaagg tcggcaatat
    29941 caatatcgaa ggtgttggcg atttcgagtg attcattttg agtcggattg acgagattga
    30001 tccaagtacc cggttcaagc gtatcgatct ctttaaattc agttgttgta gagagaaaaa
    30061 cttgtttcat atcccttatc ctttctcatt tttcagattt tttcacactg tactattata
    30121 ctacaaaatc ggccttttgg gtaatagaat ctcacttttt ttggtataat ggtaagcaat
    30181 aatggactag aaagaacaaa gatgcaagat aaaattgtca ttcatggggc gcgtgcccat
    30241 aatttaaaaa atattgatgt ggagattccg cgagacaagt tggttgtcgt gactggcttg
    30301 tcaggttcag ggaagtccag tctggctttt gatactctct atgcggaggg acaacgtcgc
    30361 tatgtagaga gtttgtctgc ctacgctcgt cagttcttgg gaaatatgga aaaaccagat
    30421 gtagatgcca ttgatggtct cagcccagct atttccatcg accagaaaac gactagtaaa
    30481 aatcctcgct cgacggtggg aacgacgact gaaatcaatg actatctgcg tctcctctac
    30541 gcacgtgtgg ggacgcctta ctgtatcaac ggacatggag ctatcaatgc ttcttctgtg
    30601 gagcaaatcg ttgataaggt tttggagtta cctgaacgcc agcgcttgca gatcttggct
    30661 cctgtcatcc gcaagaaaaa aggccaacat aagagtgtta tcgagaaggt tcagaaagac
    30721 gggtatgttc gtgttcgtgt ggatggggaa gtctatgatg tgaccgaagt gccagagttg
    30781 tctaagagca agcaacacaa tatcgatgtc gtggttgacc gtattgttat caaggagggc
    30841 attcgtagcc gtctctttga ttccattgaa gctgcccttc gtatcgcaga aggttatgtg
    30901 attatcgaca ccatggacga ctctgagttg ttgttctctg agcattatgc ctgtccagtt
    30961 tgtggattta ctgtcccaga gttagaacct cgtctcttct ctttcaatgc tccctttggc
    31021 tcttgtagtg agtgtgacgg cttggggatt aagctggagg tggatactga tttggtagtg
    31081 ccagatgcca gcaaaacctt acatgaggga gcgctggcac cttggaatcc tatctcatcc
    31141 aactactatc caaacatgtt agagcaggcc atgaaagtct ttggagtggc tatggataag
    31201 ccttttgagg acctgtcaga agaagataag aacttgattc tctacggctc agatggtaag
    31261 gaattccatt tccattatga aaatgaattt ggtggtgtgc gcgatatcga cattccgttt
    31321 gagggagtta tcaataatat caaacgtcgt taccatgaaa ccaatagcga ttacactcgc
    31381 actcagatgc gtctctacat gaatgagctg acctgcggaa cctgtcaagg ctatcgtctc
    31441 aatgaccagg ccttgtctgt ccgtgtgggc ggccagcaag ggccacatat tggagaaatc
    31501 tcagacctgt ctatcgctga ccacttggac ttggtgagcc agttaacttt gtctgaaaat
    31561 gaagccatca ttgctcgtcc cattctcaag gaaatcaagg atcgtttgac cttccttaat
    31621 aatgtgggtc ttaactatct aaccctgtca cgttcagcag gaaccctttc aggtggggaa
    31681 agtcagcgca ttcgtttggc aacccagatt ggttccaacc tatcaggtgt cctctatatc
    31741 ctagacgagc cgtcaatcgg tcttcaccag agggacaatg accgcctgat tgccagtctg
    31801 aaaaagatgc gtgacttggg caatactctt atcgtggtgg aacacgacga agataccatg
    31861 cgtgaagctg attatctgat tgacgttggt cctggtgccg gtgtttttgg tggtgagatt
    31921 gttgcagcag gtacacctaa gcaagtggct cgcaacagca agtctatcac aggtcagtac
    31981 ttgtcaggca aacgtgtcat cccagtacca gaagagcgcc gtgtcggaaa tggtcgtttt
    32041 attgaagtga caggagcgcg tgagaacaac ttgcaaaatg tcacggctcg ctttccacta
    32101 ggaaaattta tcgcagtgac aggtgtgtcg ggttcaggga aatcgactct aatcaacagc
    32161 attctcaaaa aagccattgc ccagaagctc aaccgtaatt cagacaaacc tggtaagttt
    32221 aagactatta cagggattga gcatgtcgac cgtttgattg atattgacca gagccctatc
    32281 ggacggacgc cgaggtctaa cccagctacc tatacaggag tttttgacga tatacgtgac
    32341 ctttttgctc agacaaatga agccaagatt cgaggctaca agaaggggcg cttcagtttc
    32401 aacgtcaagg gaggtcgctg tgaagcttgc tcaggtgacg ggattatcaa gattgagatg
    32461 cacttcttgc cagatgttta tgtggcttgt gaagtttgcc acggaacccg ctataacagt
    32521 gaaaccctag aagttcacta caaggaaaag aatatttcgc aggtcttgga tatgacggtc
    32581 aacgatgcgg tagaattttt ccaacacatt ccgaaaattc aacgcaaact ccagaccatc
    32641 aaggatgtag gtctaggcta tgtgaccttg ggacagccag ctaccaccct ttctggggga
    32701 gaagcccaac gtatgaagtt agctagcgaa ctccacaaac gctcgacagg aaaatctttc
    32761 tacattctgg atgagccgac gacagggctt catacagagg acattgctcg cctgctcaag
    32821 gttttagctc gctttgtaga cgccggcaat acagtcctcg tcatcgagca caatctggat
    32881 gttatcaaga cggcagacca tatcattgac ttgggacctg agggcggtgt cggtggtgga
    32941 accatcatcg taacaggaac tccagaagaa gtagctgcca acgaagccag ctatacagga
    33001 cactatttga aaggaaagtt acatcatgaa taaacgcgta caagcatttc tagctaaaat
    33061 gcaagaaaaa gaactagatg gtatcatcat caacaatctt aaaaacgtct attatttgac
    33121 tggtttttgg ggctcaaacg gaacagtctt tatcagccgt gaccgtcagg tcttagtgac
    33181 agactctcgc tatatcatcg cagctaagca agaaaccagt ggttttgaga ttgtggctga
    33241 tcgtgatgaa ttggctgtca ttgcaggaat tgttaaggac atgaacttga ctcgtatcgg
    33301 ttttgaagat gagatttcag tgtcttatta ccaccgtatg caggcagctt ttgcaggttt
    33361 gaacttgctt ccacaaactc agtttgtgga aggtcttcgt atgattaagg atgaggcaga
    33421 gattgcagcg attcgcaagg cttgttctat ctcagaccaa gctttccgcg atgcgcttga
    33481 ctttatcaaa ccaggaaaaa ctgaaattga gattgccaac ttccttgatt tccgcatgcg
    33541 tgagttggga gcatctggct tatcttttga tacgatccta gctagcggta tcaattcttc
    33601 taaaccccat gcccatccaa tgcacaaacc agtggagttg ggagaagcca ttaccatgga
    33661 cttcggctgt ctctatgacc actatgtcag tgatatgacc cggactatct atctagggca
    33721 tgttagcgat gagcaggcag agatttacaa tacggttcta aaagctaacc aagccttgat
    33781 tgaccaagct aaggcaggct taggtttccg tgactttgac aaaatccctc gtgatattat
    33841 cattgaggca ggttatggtg actactttac tcacggcatt ggccacggta ttggtctgga
    33901 tatccatgag gaaccctact ttagtcagac ttctacagaa actattaaga caggtatggc
    33961 cttgaccgat gaaccaggta tctatatcga aggcaaatat ggcgttcgta tcgaggatga
    34021 tatcctgatt acagagacag gttgtgaatt attgacccta gctccaaaag agttgatagt
    34081 catttagttg tttgtcaaga aaaaagtacg aaaatgacga aaaaagtcaa aaaaaattaa
    34141 aaataggtcg caagtcggat gttttttatg gtataataga ctaaactgat agtaacatgt
    34201 agcgaaaggg gtaggtacat gattaaaatt tatacagtct caagttgtac tagttgtaaa
    34261 aaagcaaaaa cctggctcaa tgcccaccag ttaagttata aagaacaaaa ccttggtaaa
    34321 gaaggaatta cgagagaaga attactggat attctaacca aaacagataa cggaatagcc
    34381 agcatcgttt cgtctaaaaa tcgctatgcc aaagcccttg gagtggatat tgaagatttg
    34441 agtgtcaatg aagttctcaa tctgattatg gaaacaccga gaattttaaa gagcccaatc
    34501 cttgtagatg aaaaacgcct gcaagttggc tacaaggaag acgatattcg tgccttccta
    34561 ccacgctctg tccgtaatgt agaaaatgca gaagcacgtt tgcgtgcagc tctataaaca
    34621 tcaaggctgg gagcacttcc cagtcttatt ctattttaat ttcaaaaaga aagaagaaag
    34681 aaatgaaaaa aatagttctt gttagtctag ctttcctttt tgtcctggtt ggttgcggac
    34741 agaaaaaaga aactggacca gctacaaaaa cagaaaaaga tacgcttcag tcggcattgc
    34801 cagttattga aaatgctgag aagaatacag ttgtaactaa gactttggtc ttgcccaagt
    34861 cagatgatgg tagccagcag acacaaacaa ttacttacaa agacaagact tttttgagtc
    34921 tagctatcca acaaaaacgt ccagtctctg atgagttgaa gacttatatt gaccaacatg
    34981 gagtggagga aactcaaaaa gctcttcttg aagcggagga gaaggataag tctatcattg
    35041 aagctcgtaa attggcaggt ttcaaacttg aaacaaaact attgagcgca acggaacttc
    35101 aaacaacgac tagttttgat tttcaagttc tggatgtcaa gaaggcttcc cagttggaac
    35161 atctgaagaa tattggtttg gaaaatcttt tgaaaaatga accaagcaaa tatatttcag
    35221 atagattggc aaatggcgcg acagaacaat agaaaatcca aataaataga ctgcctgaat
    35281 tgtagaaggt aaggaattat gctataatgg tactattcta aggaaagagg gtgttagaat
    35341 gggatttact gaagaaacag tacgttttaa attggacgat tccaataaaa aagaaattag
    35401 cgaaactttg acagatgttt atgcttcgtt gaacgataag ggttacaacc caattaacca
    35461 aatcgtaggt tacgtattga gtggagaccc tgcctacgtt cctcgttata ataatgcacg
    35521 aaatcaaatc cgtaagtatg agcgtgatga aatcgttgag gaattggttc gctactacct
    35581 caaaggacaa ggagtcgatc tataacctat gagaattatg ggattggacg tcggttcaaa
    35641 aacggtaggg gtggcgatta gcgatccgct tggttttaca gctcaagggc ttgaaatcat
    35701 ccagataaat gaagaacaag gccaatttgg ttttgaccgc gttaaggaat tggttgatac
    35761 ttacaaggtg gaacgatttg tagtgggctt gcctaaaaac atgaacaata caagtggacc
    35821 gcgcgtagaa gctagtcaag cctacggagc aaagctagaa gagttttttg gtttaccagt
    35881 agactatcag gatgaacgct tgacaacagt ggctgctgag cgcatgttga ttgaacaagc
    35941 agatatcagt cgcaataagc gcaagaaagt cattgataag ttagcagctc agctgatttt
    36001 acaaaattat ttagatagaa aattttaata taaaggagag gctatgtcac acgatcataa
    36061 ccacgaccac gaagaacgtg aactaatcac actagtagat gagcaaggaa atgaaacctt
    36121 gtttgaaatc cttttgacaa ttgatggaaa agaagaattt ggtaaaaact atgttcttct
    36181 agtaccagtt aacgcagaag aagacgaaga cggacaagtt gaaatccaag cttactcatt
    36241 cattgaaaat gaagatggaa cagaaggcga attgcaacca atcccagaag actcagaaga
    36301 cgaatggaac atgattgaag aagtcttcaa cagctttatg gaggagtgat acagtctggg
    36361 agactgtatc agcccaactc cagaaatggg gaagagttgg aacgtccagt gaacattttt
    36421 accccaactc ttagaaattg agaagagttg gaacatctag tggatgtttt tagcccatat
    36481 tcacattcat agtagctagt tattagctaa ccaggtaaga ggtcgggacg aaaatcctgg
    36541 ccttgttttt attagtaacc atactttaat gcgataattg attggacttt tgtcaaggag
    36601 atgtgtatgt ttgaagtaga agaatggctc catagtcgga ttggtttgaa ttttcgatca
    36661 ggtttgggcc gaatgcagca agcggtggat ttgttaggaa atcctgagca gtcttaccct
    36721 attatccacg taacagggac taatgggaaa ggatctacca ttgcttttat gagggaatta
    36781 tttatggggc atggcaaaaa agttgcgacc tttacctccc ctcatatcgt ctctatcaat
    36841 gaccgaatct gcattaatgg gcaacctata gcagacgcag actttatccg tttgactgat
    36901 caggtcaagg agatggagaa aacgcttctg caaactcctg cccagttgtc cttttttgaa
    36961 ttgctgacct tagttgcttt tctttatttt agggagcaag aggtggattt ggttttatta
    37021 gaagtgggaa ttggtggctt acttgacacg accaatgtgg taactggaga gcttgctgtc
    37081 atcacctcca ttgggcttga ccatcaagaa accttgggtg atagtctaga agcaattgca
    37141 gagcagaaag ctggtatttt caaggctggt aaaaaggcag tgattgcgaa attgcctcca
    37201 gaagctagac ttgtctgtca gaaaaaagcc gaatctttag ctgttgacct ttatcaggca
    37261 ggtcaagatt tttcagtgct gaatggtgat ttttcaagct ctttactaaa tctttcacag
    37321 ctgaacatag gcttagaagg agcctatcag caggagaatg cggccttggc gttgcaaact
    37381 tttcttcttt ttatgggaga aagaaaggaa gctattgatg aacaggctgt aagaaaggcc
    37441 ttggaacaga cccattgggc tggtcgcttg gagcgtattc gcccacagat ttacttggat
    37501 ggtgctcata acctccctgc cttgactcgc ttggttgagt ttatcaaaga aaaagagcag
    37561 gaaggctatc gacctcaaat cctctttgga tccttgaaac gtaaggatta tcaagggatg
    37621 ttgggttatc tgactgaaaa tttacctcaa gtggaactca aaatgaccgg ctttgactat
    37681 caagggtctt tggacgagac agatgtaaca ggttaccatg taattccctc ttaccgagaa
    37741 tttatcagca gtttcgaaga aagggcagac gctcaagact tgctgttcgt tacagggtct
    37801 ctctatttta tctcagaagt acggggctac ctgctggacc gtgagcagat aaattgaccc
    37861 ccttttttga acttgttata ctaggggaat tgctggttag agaaaatttc tctaaattgg
    37921 tagcagaaag gaaattcatc atgaaattaa aaagattcac actttctctt gcttctctag
    37981 caagttttag tctcttagta gcttgttcac aaagagctca acaggttcaa cagcctgttg
    38041 ctcagcaggt ccaacagcct gctcaacaga ataccaatac tgcaaatgca ggaggtaacc
    38101 aaaatcaagc ggctccagta caaaaccaac ctgttgctca accgaccgat attgatggga
    38161 cttatactgg tcaggatgac ggagaccgta tcactttagt ggtaactgga acgactggta
    38221 catggactga gctcgaatct gacggggatc agaaagtcaa acaggttaca tttgattcag
    38281 caaatcaacg catgattatt ggcgatgatg tcaaaattta cactgtaaac ggtaatcaaa
    38341 tcgtcgtaga tgatatggat agagacccat cggaccaaat cgttttaact aaataagact
    38401 atgcaagtag aaagggctgg atttttcagc ctttttactt ttacctagaa aataatcata
    38461 aatacttgcc ttctaccgaa tacctgcgtt atactagtat caattacttg tttttagcat
    38521 tcaaactatc aaggagggga tatgaaatat aggaaatttc aattattgat gtccaagtat
    38581 ggctttagtc tttcgattat gctacttgaa ctttgtcttg tttttggtct ctttctttat
    38641 ttaggacgca tggctcccat tttatggatt actgtcctca ttctactgag tatcatcaca
    38701 atcatttcga tagtcaaccg taatacgact cctgagaata aggtaacctg gttgttagta
    38761 gcctttgtgc cagtatttgg tcccttgctc tatctgatgt ttggtgaaag gcgattgtcc
    38821 aaaaaagaaa tcaaacaact gaagaagcta ggctctatgc atttccaaga agcaaatagc
    38881 cagctactaa aagagaaatt aaaagaaagt gacaaggcag cttatggagt catcaagtcc
    38941 ttattgagta tggataccaa tgctgacatc tatgatcaaa ctgcctctac attttttcct
    39001 aacggagaag ctatgtggaa aaagatggta gaagatctta aaaaggctga gaaatttatt
    39061 ttcttggaat attacattat agaagaaggt ttgatgtgga atcgcatact agatatacta
    39121 gagcaaaagg tagctcaggg tgtagaggtt aagatgctct atgatgatat cggctgtatg
    39181 gctactttaa caggagatta tgcacatcga cttcgtcagc tgggcatcga ggcccataaa
    39241 ttcaataaag ttattcctcg tttgacagtg gcttataata acagagatca tagaaaaata
    39301 ttgattgttg atggtcagat agcctatact ggtggggtca atctggcaga tgagtacatt
    39361 aaccacgtcg agagatttgg ttattggaag gatagtggaa ttcgcttaga cggactagca
    39421 gtaaaagccc tgacacgctt atttttgacc acttggtaca ttaatcgagg agaaattagt
    39481 gattttgatc aatatcattt agaaaatcat tctatcccga gtgacggttt aaccattcca
    39541 tacggaagtg gacccaagcc aatttttcga gcgcaggtag ggaaaaaagt ttatcagagt
    39601 ttaatcaatc aagcaacaga atcggtctat attacgacac cttatttgat tatagattat
    39661 gatttaacag agacaatcaa aaatgcagct atgagagggg tcgatgttcg aattatcacc
    39721 ccttacatac cagataagaa gttcattcag ttagtcacga gaggagctta tcccgacctt
    39781 ctttctgctg gtgttcggat ttatgagtat agtccaggtt ttattcatag taagcagatg
    39841 ttggtagacg aagattttgc ggtggtgggg acaatcaatc tcgactaccg gagcttggta
    39901 caccattatg aaaatgcagt cttactctat aaaactcctt ctataaggga aatcgcccga
    39961 gattttcgaa atatatttgc agattctcag gaagtctatc ctcattctat caaaacgagc
    40021 tggtatcaaa agcttgtaaa agaaatcgcc cagctattcg cccctatctt ataagaaatc
    40081 tagaacttag gatacaaacc agacctattt ttcttgtctt ttactaatag aaagaaagag
    40141 gaggggaatt catgctaact aaggaagaag tgaatgatat gattgagttc aaacagacac
    40201 atttataccg ctttcgggaa attgaaacct ttgtgaaact atgcaaaaaa tcactcaaac
    40261 agccatcgca agctgacaat cctaggactt tttgatatac taagacagat aaattgaaca
    40321 ggagaaacga tatgagtgtg tatggtagag tagaagaagt tcataaggag aatcgtgaac
    40381 ctctagaata ccaaatcgaa caagaatcgc atcatcgtga atcaagtcgt cttcctttgg
    40441 tgaaaatttt actatggagt acgcttgtaa cggggataac tctaggagta ccgctattac
    40501 tcgacttaat gagtgcacaa gaagtgcagg atttttatgc aggttggggg cttcatcaga
    40561 cagggaagat ttacagcgac tattatggaa gtcaaggttt gctttattat ttgctgactt
    40621 acgtgagtca gggcggattt ttctttgcca tctttgagtg gttagccttg gtagcaggag
    40681 gatttttcct ttttagatca gcggacacct tgacagagca aggagaccaa gctggacatc
    40741 tggtgactat tttttacatg ctagttacag gtcttgcttt tggtggaggc tatgcgactc
    40801 ttttagcgct tcctttctta ttcgcagcct ttagtttagt tgcggcttac ctaagcaatc
    40861 caagccatga taagggattt gtacggattg ggctagcttt ggcaggcgga tttttctttg
    40921 ctcccttatc atcgctcctg tttattgctg tagtgagttt aggcttgttg gtctttaacc
    40981 ttgggcatag acgctttgcg catgggtttt atcagtttct tgcagtggct ttaggttttt
    41041 cacttgtctt ttatccaact gcctactata gtgctgcaac aggaagtttt ggggatgcga
    41101 ttagtggtat tcgttatcct attgacagta ttcgctttga ttttacttct aaaattttag
    41161 agaatatgtt tttttatggc ttgttgtccc ttggtttggg atttgtggtt tgtatctttt
    41221 taggtctctt tcaatccaaa ccctttaaac tatacgtcat ttcggttcct gcaagtcttg
    41281 tggtaatttt aggtttgatt ttacttttct tttcacaaga gcctctgcac gcttcttatt
    41341 tgatggtcgt cttccctgtt ttcctacttt tattggtaac caatattaag agtcaacaga
    41401 gggggcgtag tgctagaaga agccgaagag aaacgccagt tagcctatgg agtcgtttct
    41461 tcaaaggaaa tctatatctg ctagtttttg ggtttgtcta tcttttgtct gttccttttt
    41521 tgatgaagtt tgtcctttat ccagtacctt atcaagaacg taatcgtctt gctgatttgg
    41581 taaaagagga gacaaatacg gaagatgcta tctatgcatg ggatgatact gcgactcttt
    41641 atcgtaagag tgagcgcttg tcgccatcgg cgattttgtc cccgttgcac tatacagcaa
    41701 ctgaggaaaa tcgtaataag ttacttaatg acttgaaaga aaaacaacct aaggtgattg
    41761 tggtaaatga caaggtggta gtctggtctg aagtggaaac acttttaaaa gaaaattacc
    41821 aacaagtaaa gactgattac tcagagttta aagtctataa aattaaataa ccaaatcaat
    41881 atcttgtgta tttttaaaaa ttttaggatt tttaacacaa gatattgatt tttcttttta
    41941 gagtggtata atacttttta gaaagaacat tttagaaaag agcatgcgta tgattgcact
    42001 agaagaaaaa attacaattt tgccaactct cttcgtcgag aaacgagatg ggagacgtgt
    42061 tgtatttgat gtggacaaga ttgacaaggc tctccacaag gcggctgaca aggttatgga
    42121 tgtgacaccc ctggttgaaa aacgcctcaa tgatctgact gagcgaatta ttacagaaat
    42181 tcatagtcgc tttccacagg gaattaagat ttacgaaatt caaaatatcg tagaacatga
    42241 actccttgaa gccaaagaat atgcgctggc tgaggagtat attacttatc ggacacagag
    42301 ggattttgag cgctcaaaag cgacggatat caactttagt attcataaac ttctcaacaa
    42361 agaccagaca gttgtcaatg aaaatgctaa taaagacagt gatgtcttta acactcagcg
    42421 tgatttgaca gcagggattg ttgggaaatc aatcggactg caaatgcttc ctaagcacgt
    42481 agccaatgcc caccaaaagg gggatatcca ctatcacgat ttggactaca gtccctatac
    42541 ccctatgacc aactgctgtt tgattgattt taagggtatg ttggaaaatg gttttaagat
    42601 tggaaatgca gaggtagaga gtcccaagtc tatccagact gcgacagcac agatttctca
    42661 aatcattgcc aacgttgctt ctagccagta cggtggctgt tcagctgacc gtatcgatga
    42721 aattttggcg ccttatgcag agaagaatta tcaaaaacat ctcaaagatg cagaagagtg
    42781 ggtattgcct gaaaaacggg aagattacgc ttggaagaaa acgcaaaagg acatctacga
    42841 tgccatgcaa tctcttgagt atgaaatcaa tactctcttc acttcaaatg gacaaacacc
    42901 ttttacttcg ttaggttttg gtctgggaac cagtcgtttt gaacgagaaa ttcaaaaagc
    42961 tattttaaac attcgcatca agggtcttgg ttcagaacac cgtacggcta tctttcctaa
    43021 acttattttc actctgaaaa gaggccttaa tttagaggaa ggaactccca actacgacat
    43081 caagcagttg gctcttgagt gtgcaaccaa acggatgtat ccagatgttt tatcttacga
    43141 taagattgtt gacttgacag gatccttcaa ggtgcctatg ggttgccgtt ctttcctcca
    43201 aggatggaag gatgaaaatg gtgtagaagt caattcaggt cgcatgaatc tgggtgttgt
    43261 gacggttaat ctgcctcgta ttgctcttga gtctgaaggt gatatgaata agttctggga
    43321 aatcttcaac gagcgaatga atatcgcaga agatgctctt gtttaccgtg tcgaacgcac
    43381 taaagaggcg acaccagcaa atgctcctat tctttatcag tacggtgctt ttggccatcg
    43441 tctaggtaaa gaagaaagtg ttgaccagct ctttaagaat cgtcgtgcta ccgtttcgct
    43501 gggctatatc ggcttgtatg aagtagcgac agttttcttt ggtaacagct gggaaagtaa
    43561 tccagatgct aaggaattca cgctagacat cattcacgat atgaaacgcc gtgtagaaga
    43621 gtggtcagac caatatggct accatttctc tatctactca acaccatccg aaagtctgac
    43681 agaccgtttc tgtcgactag atatagacaa gtttggctct attcctgata tcacagacaa
    43741 ggaatactac accaactctt tccactacga tgttcgtaaa aatccaacac cgtttgaaaa
    43801 attggacttt gagaaagtct atccagaagc aggtgcgtca ggtggtttca tccattattg
    43861 tgagtatcca gtccttcagc aaaatccaaa ggccttggaa gctgtctggg attatgctta
    43921 tgaccgtgta ggctatctag gcaccaatac tccgattgac cgttgctaca agtgtgactt
    43981 tgaaggggat tttgaaccaa ctgagagagg gtttgcttgt ccaaactgtg gcaatagcga
    44041 ccctaaaaca gtagatgtgg tgaagcgaac ttgtggctac ctaggtaatc ctcaagcaag
    44101 accgatggtc aacggccgtc acaaggaaat cgctgcgcgt gtcaaacata tgaatggttc
    44161 aacgattaaa atagctgggc atcaagtaac aaattagaaa gaaatgaaat gggaaaatat
    44221 caactagacg ataaggggcg cgcacaagtg acccgttatc acgagaaaca ctctaaaggt
    44281 ggagctggta agaaagaacg cttgcttagc ttcagagaac aatttttaaa caagaacaag
    44341 aaaaaataaa agtgagagcc agctctcgct tttctcatag tgggaggtaa ggatggaatt
    44401 acgcagacca agattagcgg ataagaaagc tgttttagat atgatgacag agtttgaaaa
    44461 atttcagtcg cctcacgacg gcggtttctg ggatacagag aactttgtgt atgaagactg
    44521 gttagaaagc aatcaggaac aggaaatggg gattaatctg cctgaaggat gggttcctgc
    44581 aattcagtta gtggcttttt ctgagaaagg tcaagcagtt ggatttctta atctccggtt
    44641 gcgcctcagt aactttctac tagaagaagg tggccacatt ggctactcca ttcgtccatc
    44701 tgaaagaggc aagggttatg caaaagagac tctccgtcag ggcttgcaag ttgctaagga
    44761 aaagaacatc aagaaagctc tggtgacctg tagcgtgaat aatcctgcta gcagagcagt
    44821 cattctagca aatggtggaa tatttgagga tgctcgcaat ggagtcgagc gttattggat
    44881 agaggtagcg aatgaataat ccaaaaccac aagaatggaa aagcgaggaa cttagtcaag
    44941 gtcgtatcat tgactacaag gcctttaact ttgtggacgg cgaaggcgtg cgtaactctc
    45001 tctatgtatc aggctgtatg tttcactgcg agggatgtta taatgttgca acttggtctt
    45061 ttaatgctgg cattccctat acagcagaat tagaagagca gatcatggca gatcttgctc
    45121 agccctatgt tcaaggtttg actttgttgg gaggggagcc ttttcttaat actgggattc
    45181 tcttgccact tgttaagcgg attcggaagg aattgccaga caaggacatc tggtcctgga
    45241 ccggctacac ttgggaagaa atgatgttgg aaactccaga taaactggaa ttcttgtcac
    45301 tgattgacat tcttgtcgat ggaagatatg atcgaactaa gagaaatctt atgctccagt
    45361 ttcgaggttc atctaaccaa cgaattatcg atgtgcaaaa atcgctcaaa agtgggcaag
    45421 tagtgatttg ggacaagctc aatgacggaa aagaaagcta tgaacaggtg aagagagaat
    45481 gaagaaaaaa tgaagaaaaa agacttagta gaccaactag tctcagagat cgagacgggg
    45541 aaagtcagga cactgggaat atacggtcat ggagcttcag gtaaatcaac ctttgcacag
    45601 gaattgtacc aagctttaga ttctactaca gtaaatttgc tagaaacaga tccctatatc
    45661 acctccggac gctatttggt agtacccaag gacgcgccga atcaaaaggt gacagccagt
    45721 ctgccagtgg cgcatgaact ggagagtttg cagagagata tccttgcctt gcaggcgggt
    45781 atggatgtct tgacaattga agaaccttgg aaggctagtg aggtcttgtc tggagccaaa
    45841 ccaattttga ttgtcgaagg gatgtctgtt ggttttctac ccaaggaact ctttgaaaaa
    45901 accatctgtt tctacacgga tgaggagacc gaattaaagc gacgccttgc tagagatacg
    45961 actgtgagaa atcgctatgc atcctttata ttggctagcc atcagatgag acgggagcag
    46021 tatctgcgat actataaaga aactgagtct aaggcggata tcttagtgga ccaatcagaa
    46081 gataaatttg atgtcaagag gacttaactt atgtatagaa gaaatataga agaaaatccc
    46141 taattttaga aagaaaaagt aggaaaacag tttcatccca aaaaaacgaa aaaacctaac
    46201 aaatcccttg caatcgcagg ggatttgtgt tattctatta tggtgctgta aattacagcc
    46261 ttagttttga tgcaagaggt tgcgacacgc tcggttgcat tgccacgcaa caccgcgtcg
    46321 gttttcttgt ggagctagcc tattatctta aatagacgaa aaggagaaaa agatggcaaa
    46381 caaaaaaatc cgtatccgtt tgaaagctta cgaacaccgt acgcttgaca cagcggctgc
    46441 aaaaatcgta gaatcagcta ctcgtacagg tgcacaagtt gcgggtccaa tcccacttcc
    46501 aactgaacgt agcctctaca caatcattcg tgcgactcac aaatacaaag actctcgcga
    46561 acaatttgaa atgcgtacac acaaacgttt gatcgatatc gttaacccaa ctcaaaaaac
    46621 agttgatgcc ttgatgaaat tggatcttcc aagtggtgta aacgtagaaa tcaaacttta
    46681 atctaaaata taaaagagca gaggctggtg tttcaatcta attgaacacg ggctaaactc
    46741 ggtgtgaaaa agataaactt cctcgcgtct gctagacact gtgtcagttt cctattttca
    46801 ctttgagttt gacgcccttt gtatcttaga cttgagcata aaaaacgctc gttaaaaact
    46861 ttttgaataa aaaatataga aaaggaacta ttttctcatg acaaaaggaa tcttagggaa
    46921 aaaagtggga atgactcaaa tcttcactga agctggcgaa ttgatccctg taacagttat
    46981 tgaagcaact ccaaacgttg ttcttcaagt taaaactgtt gaaacagacg gatacaacgc
    47041 tatccaagtt ggtttcgatg acaaacgcga agtattgagc aacaaacctg ctaaaggaca
    47101 tgtagcgaaa gctaacacgg ctcctaagcg cttcattcgt gaattcaaaa acgttgaagg
    47161 cttggaagtt ggtgctgaaa ttacagttga aacattcgca gctggagacg ttgttgacgt
    47221 aactggtact tctaaaggta aaggtttcca aggtgttatc aaacgccacg gacaatcacg
    47281 tggaccaatg gctcacggtt ctcgttacca ccgtcgtcca ggttctatgg gacctgttgc
    47341 acctaaccgc gtattcaaag gtaaaaacct tgcagggcgt atgggtggcg accgcgtaac
    47401 aattcaaaac cttgaagttg tacaagttgt tccagaaaag aacgttatcc ttatcaaagg
    47461 taacgtacca ggtgctaaga aatctcttat cactatcaaa tcagcagtta aagctggtaa
    47521 ataataaaga aaggggaaat cagtcacaat ggcaaacgta acattatttg accaaactgg
    47581 taaagaagct ggccaagttg ttcttagcga tgcagtattt ggtatcgaac caaatgaatc
    47641 agttgtgttt gatgtaatca tcagccaacg cgcaagcctt cgtcaaggaa cacacgctgt
    47701 taaaaaccgc tctgcagtat caggtggtgg acgcaaacca tggcgtcaaa aaggaactgg
    47761 acgtgctcgt caaggttcta tccgctcacc acaatggcgt ggtggtggtg ttgtcttcgg
    47821 accaactcca cgttcatacg gctacaaact tccacaaaaa gttcgtcgcc tagctcttaa
    47881 atcagtttac tctgaaaaag ttgctgaaaa caaattcgta gctgtagacg ctctttcatt
    47941 tacagctcca aaaactgctg aatttgcaaa agttcttgca gcattgagca tcgattctaa
    48001 agttcttgtt atccttgaag aaggaaatga attcgcagct ctttcagctc gtaaccttcc
    48061 aaacgtgaaa gttgcaactg ctacaactgc aagtgttctt gacatcgcaa atagcgacaa
    48121 acttcttgtc acacaagcag ctatctctaa aatcgaggag gttcttgcat aatgaatttg
    48181 tatgatgtta tcaaaaaacc tgtcatcact gaaagctcaa tggctcaact tgaagcaggg
    48241 aaatatgtat ttgaagttga cactcgtgca cacaaacttt tgatcaagca agctgttgaa
    48301 gctgctttcg aaggtgttaa agttgccaat gttaacacaa tcaacgtaaa accaaaagct
    48361 aaacgtgttg gacgttacac tggttttact aacaaaacta aaaaagctat catcacactt
    48421 acagctgatt ctaaagcaat cgagttgttt gctgctgaag ctgaataatc taaggaggaa
    48481 atatcgtggg aattcgtgtt tataaaccaa caacaaacgg tcgccgtaat atgacttctt
    48541 tggatttcgc tgaaatcaca acaagcactc ctgaaaaatc attgcttgtt gcattgaaga
    48601 gcaaggctgg tcgtaacaac aacggtcgta tcacagttcg tcaccaaggt ggtggacaca
    48661 aacgttttta ccgtttggtt gacttcaaac gtaataaaga caacgttgaa gcagttgtta
    48721 aaacaatcga gtacgatcca aaccgttctg caaacatcgc tcttgtacac tacactgacg
    48781 gtgtgaaagc atacatcatc gctccaaaag gtcttgaagt aggtcaacgt atcgtttcag
    48841 gtccagaagc agatatcaaa gtcggaaacg ctcttccact tgctaacatc ccagttggta
    48901 ctttgattca caacatcgag ttgaaaccag gtcgtggtgg tgaattggta cgtgctgctg
    48961 gtgcatctgc tcaagtattg ggttctgaag gtaaatatgt tcttgttcgt cttcaatcag
    49021 gtgaagttcg tatgattctt ggaacttgcc gtgctacagt tggtgttgtc ggaaacgaac
    49081 aacatggact tgtaaacctt ggtaaagcag gacgtagccg ttggaaaggt atccgcccaa
    49141 cagttcgtgg ttctgtaatg aaccctaacg atcacccaca cggtggtggt gaaggtaaag
    49201 caccagttgg tcgtaaagca ccatctactc catggggcaa acctgctctt ggtcttaaaa
    49261 ctcgtaacaa gaaagcgaaa tctgacaaac ttatcgttcg tcgtcgcaac gagaaataat
    49321 attaaactag tcgcttaagc aactagtaaa tccgccagct cggtagcgct ccataggagt
    49381 gcaagccgct gtggtacaac atttaaagga gaaaatataa aaatgggacg cagtcttaaa
    49441 aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc taacgacgaa
    49501 aagaaaaaag ttattaaaac ttggtcacgt cgttcaacga tcttcccaag tttcattggt
    49561 tacactattg cagtttatga cggacgtaaa cacgtacctg tttacatcca agaagacatg
    49621 gtaggccaca aacttggtga atttgcacca actcgtactt acaaaggtca cgctgcagac
    49681 gacaagaaaa cacgtagaaa ataaggagaa cataaatggc agaaattact tcagctaaag
    49741 caatggctcg tacagtacgt gtttcacctc gtaaatcacg tcttgttctt gataacatcc
    49801 gtggtaaaag cgtagccgat gcaatcgcaa tcttgacatt cactccaaac aaagctgctg
    49861 aaatcatctt gaaagttttg aactcagctg tagctaacgc tgaaaacaac tttggtttgg
    49921 ataaagctaa tttggtagta tctgaagcat tcgcaaacga aggaccaact atgaaacgtt
    49981 tccgtccacg tgcgaaaggt tcagcttcac caatcaacaa acgtacagct cacatcactg
    50041 tagctgttgc agaaaaataa ggaggtaaaa tcgtgggtca aaaagtacat ccaattggta
    50101 tgcgtgtcgg catcatccgt gattgggatg ccaaatggta tgctgaaaaa gaatacgcgg
    50161 attaccttca tgaagatctt gcaatccgta aattcgttca aaaagaactt gctgacgcag
    50221 cagtttcaac tattgaaatc gaacgcgcag taaacaaagt taacgtttca cttcacactg
    50281 ctaaaccagg tatggttatc ggtaaaggtg gtgctaacgt tgatgcactc cgtgcaaaac
    50341 ttaacaaatt gactggaaaa caagtacaca tcaacatcat cgaaatcaaa caacctgatt
    50401 tggatgctca ccttgtaggt gaaggaattg ctcgtcaatt ggagcaacgt gttgctttcc
    50461 gtcgtgcaca aaaacaagca atccaacgtg caatgcgtgc tggagctaaa ggaatcaaaa
    50521 ctcaagtatc aggtcgtttg aacggtgcag atatcgcccg tgctgaagga tactctgaag
    50581 gaactgttcc gcttcacaca cttcgtgcag atatcgatta cgcttgggaa gaagcagata
    50641 ctacatacgg taaacttggt gttaaagtat ggatctaccg tggtgaagtt cttccagctc
    50701 gtaaaaacac taaaggaggt aaataaccaa tgttagtacc taaacgtgtt aaacaccgtc
    50761 gtgagttccg tggaaaaatg cgcggtgaag caaaaggtgg aaaagaagta gcattcggtg
    50821 aatacggtct tcaagctaca actagccact ggatcactaa ccgccaaatc gaagctgctc
    50881 gtatcgccat gactcgttac atgaaacgtg gtggtaaagt ttggattaaa atcttcccac
    50941 acaaatcata cactgctaaa gctatcggtg tgcgtatggg atctggtaaa ggggcacctg
    51001 aaggttgggt agcaccagtt aaacgtggta aagtgatgtt cgaaatcgct ggtgtatctg
    51061 aagagattgc acgtgaagcg cttcgacttg ctagccacaa attgccagtt aaatgtaaat
    51121 tcgtaaaacg tgaagcagaa taaggagaag gcatgaaact taatgaagta aaagaatttg
    51181 ttaaagaact tcgtggtctt tctcaagaag aactcgcgaa gcgcgaaaac gaattgaaaa
    51241 aagaattgtt tgaacttcgt ttccaagctg ctactggtca attggaacaa acagctcgct
    51301 tgaaagaagt taaaaaacaa atcgctcgta tcaaaacagt tcaatctgaa gcgaaataat
    51361 agactaggga aggagaaatt tcaatggaac gcaataatcg taaagttctt gttggacgtg
    51421 ttgtatctga caaaatggac aagacaatca cagttgtagt tgaaacaaaa cgtaaccacc
    51481 cagtctatgg taaacgtatt aactactcta aaaaatacaa agctcatgat gaaaacaatg
    51541 ttgccaaaga aggcgatatc gtacgtatca tggaaactcg cccgctttca gctacaaaac
    51601 gtttccgtct tgtagaagtt gttgaagaag cggtcatcat ctaatcaaac ctgaaaggag
    51661 aaaactgaaa tgattcaaac agaaactcgt ttgaaagtcg cagacaacag cggtgctcgc
    51721 gaaatcttga ctatcaaagt tcttggtggt tcaggacgta aatttgcaaa catcggtgat
    51781 gttatcgtgg catctgtaaa acaagctact cctggtggtg cggttaaaaa aggtgacgtt
    51841 gttaaagcag ttatcgttcg tactaaatca ggtgctcgtc gtgctgatgg ttcatacatc
    51901 aaatttgacg aaaacgcagc agttatcatc cgtgaagaca aaactcctcg cggaacacgt
    51961 atctttggcc cagttgcacg tgaattgcgt gaaggtggct tcatgaagat cgtgtcactt
    52021 gctccagaag tactttaatt tttaggaaca aactagtccc ctagcttcaa gctagggtgc
    52081 ccttatgggc gtaagaaaaa tcaaggagaa acctaatgtt tgtaaaaaaa ggcgacaaag
    52141 ttcgcgtaat cgctggtaaa gataagggaa cagaagctgt tgtccttact gcccttccaa
    52201 aagtaaacaa agttatcgtt gaaggtgtta acattgttaa gaaacaccaa cgtccaacta
    52261 acgagcttcc tcaaggtggt atcatcgaga aagaagcagc tatccacgta tcaaacgttc
    52321 aagttttgga caaaaatggt gtagctggtc gtgttggtta caaatttgta gacggtaaaa
    52381 aagttcgcta caacaaaaaa tcaggcgaag tgcttgatta atcacgaagg aaaggagaag
    52441 tataatggca aatcgtttaa aagaaaaata tcttaatgaa gtagttcctg ctttgacaga
    52501 acaattcaac tactcatcag tgatggctgt gcctaaagta gataagattg ttttgaacat
    52561 gggtgttggt gaagctgtat caaacgctaa aagccttgaa aaagctgctg aagaattggc
    52621 acttatctca ggtcaaaaac cacttatcac taaagctaaa aaatcaatcg ccggcttccg
    52681 tcttcgtgaa ggtgttgcga tcggtgcaaa agttaccctt cgtggtgaac gtatgtacga
    52741 attcttggat aaattggtat cagtttcact tccacgtgta cgtgacttcc acggtgttcc
    52801 aacaaaatca tttgatggac gcgggaacta cacacttggt gtgaaagaac aattaatctt
    52861 cccagaaatc aacttcgatg acgttgacaa aactcgtggt cttgacatcg ttatcgtaac
    52921 aactgctaac actgacgaag agtcacgtgc attgcttaca ggccttggaa tgccttttgc
    52981 aaaataatat aggaggtaaa tctaatggct aaaaaatcaa tggtagctag agaggctaaa
    53041 cgccaaaaaa ttgttgaccg ttatgctgaa aaacgtgctg cattaaaggc ggcaggggac
    53101 tacgaaggtt tatctaaatt acctcgcaac gcttcaccga ctcgtttaca taatcgttgt
    53161 agagttacgg ggcgcccaca ttcagtttac cgcaaatttg gtctgagtcg tatcgctttt
    53221 cgcgaacttg cgcataaagg tcaaattcct ggtgtaacaa aagcatcttg gtaatttaag
    53281 atatcaaggg cgtcaaaact ccaagtaaaa ataggaaact tgacgaagaa actaaagttt
    53341 ctaggaaagt ttatcttttt cacacagagt ttagcccggg ttcaattggg cttgccaatt
    53401 tgaacacgag ctacagcttt ggcaaaaaag accaatttgc tttggagcat tgcttctgca
    53461 ttaaattgtc tatttttgct cgtgctgtta cgctctttgt atcatgtatt aactagcaag
    53521 tgcaacttgc aaactactag taagaggaga aaaacaaaat ggttatgact gacccaatcg
    53581 cagacttcct aactcgtatt cgtaatgcta accaagctaa acacgaagta cttgaagtac
    53641 ctgcatcaaa catcaaaaaa gggattgctg aaatccttaa acgcgaaggt tttgtaaaaa
    53701 acgttgaaat catcgaagat gacaaacaag gcgtcatccg tgtatttctt aaatacggac
    53761 caaatggtga aaaagttatc actaacttga aacgtgtttc taaaccagga cttcgtgtct
    53821 acaaaaaacg tgaagacctt ccaaaagttc ttaacggact tggaattgcc atcctttcaa
    53881 cttctgaagg tttgcttact gataaagaag cacgccaaaa gaatgttggt ggtgaggtta
    53941 tcgcttacgt ttggtaaaat caagatacaa agctcgtaaa gaacaaagca aaattaggaa
    54001 gttggagaag tttgtttaca aacaagccaa cttatctatt ttgcacagtt cttagagcgt
    54061 gttcagttca gctcttgaac taaataagta tctgaacccc gtgaaaactg gccgttttgg
    54121 cctgacaatt taacaggaga aaataaacat gtcacgtatt ggtaataaag ttatcgtgtt
    54181 gcctgctggt gttgaactcg ctaacaatga caacgttgta actgtaaaag gacctaaagg
    54241 agaacttact cgtgagttct caaaagatat tgaaatccgt gtggaaggta ctgaagtaac
    54301 tcttcaccgt ccaaacgatt caaaagaaat gaaaactatc cacggaacta ctcgtgccct
    54361 tttgaacaac atggttgttg gtgtatcaga aggattcaag aaagaacttg aaatgcgtgg
    54421 ggttggttac cgtgcacagc ttcaaggatc taaacttgtt ttggctgttg gtaaatctca
    54481 tccagacgaa gttgaagctc cagaaggaat tacttttgaa cttccaaacc caacaacaat
    54541 cgttgttagc ggaatttcaa aagaagtagt tggtcaaaca gctgcttacg tacgtagcct
    54601 tcgttcacca gaaccatata aaggtaaagg tatccgttac gttggtgaat tcgttcgccg
    54661 taaagaaggt aaaacaggta aataatgttg agtggttgat catcaaccac caacctattt
    54721 tccaactttg tgcatagcac acgatttaaa actaaagagg tgaaaactgt gatttcaaaa
    54781 ccagataaaa acaaactccg ccaaaaacgc caccgtcgcg ttcgcggaaa actctctgga
    54841 actgctgatc gcccacgttt gaacgtattc cgttctaata caggcatcta cgctcaagtg
    54901 attgatgacg tagcgggtgt aacgctcgca agtgcttcaa ctcttgataa agaagtttca
    54961 aaaggaacta aaactgaaca agccgttgct gtcggtaaac tcgttgcaga acgtgcaaac
    55021 gctaaaggta tttcagaagt ggtgttcgac cgcggtggat atctatatca cggacgtgtg
    55081 aaagctttgg ctgatgcagc tcgtgaaaac ggattgaaat tctaatagga ggacactaga
    55141 aaatggcatt taaagacaat gcagttgaat tagaagaacg cgtagttgct gtcaaccgtg
    55201 ttacaaaagt tgttaaaggt ggacgtcgtc ttcgtttcgc agctcttgtt gttgttggtg
    55261 accacaatgg tcgcgtagga tttggtactg gtaaagctca agaagttcca gaagcaatcc
    55321 gtaaagcagt agatgatgct aagaaaaact tgatcgaagt tcctatggtt ggaacaacaa
    55381 tcccacacga agttctttca gaattcggtg gagctaaagt attgttgaaa cctgctgtag
    55441 aaggttctgg agttgccgct ggtggtgcag ttcgtgccgt tgtggaattg gcaggtgtgg
    55501 cagatattac atctaaatca cttggttcta acactccaat caacattgtt cgtgcaactg
    55561 ttgaaggttt gaaacaattg aaacgcgctg aagaaattgc tgcccttcgt ggtatttcag
    55621 tttctgattt ggcataagaa aggggataaa atggctcaaa ttaaaattac tttgactaag
    55681 tctccaatcg gacgcattcc atcacaacgt aaaactgttg tagcacttgg acttggcaaa
    55741 ttgaacagct ctgttattaa agaagataac gctgctatcc gtggtatgat tacagcagta
    55801 tctcacttag taacagttga agaagtaaac taatgaagtt ttaggggatg tgcactgtac
    55861 catcccctaa aactagatat agtcatctat gatgacatcg tataggcgag ttgatggggg
    55921 agacaacctt ttctccctta tcggcgctag cattttacaa aagaggagaa aataaaaatg
    55981 aaacttcatg aattgaaacc tgcagaaggt tctcgtaaag tacgtaaccg cgttggtcgt
    56041 ggtacttcat caggtaacgg taaaacatct ggtcgtggtc aaaaaggtca aaaagctcgt
    56101 agcggtggcg gagttcgcct tggttttgaa ggtggacaaa ctccattgtt ccgtcgtctt
    56161 ccaaaacgtg gattcactaa catcaacgct aaagaatacg caattgtgaa ccttgaccaa
    56221 ttgaacgtct ttgaagatgg tgctgaagta actccagttg ttcttatcga agcaggaatt
    56281 gttaaagctg aaaagtcagg tattaaaatt cttggtaacg gtgagttgac taagaaattg
    56341 actgtgaaag cagctaaatt ctctaaatca gctgaagaag ctatcactgc taaaggtggt
    56401 tcagtagaag tcatctaaga gaggtgacct atgtttttta aattattaag agaagctctt
    56461 aaagtcaagc aggttcgatc aaaaatttta tttacaattt ttatcgtttt ggtctttcgt
    56521 atcggaacta gcattacagt tcctggtgtg aatgccaata gcttgaatgc tttaagtgga
    56581 ttatccttct taaacatgtt gagcttggtg tcggggaatg ccctaaaaaa cttttcgatt
    56641 tttgccctag gagttagtcc ctatatcacc gcttctattg ttgtccaact cttgcaaatg
    56701 gatattttac ccaagtttgt agagtggggt aaacaagggg aagtaggtcg aagaaaattg
    56761 aatcaagcta ctcgttatat tgctctagtt ctcgcttttg tgcaatctat cgggattaca
    56821 gctggtttta ataccttggc tggagctcaa ttgattaaaa ctgctttaac tccacaagtt
    56881 tttctgacga ttggtatcat cttaacagct ggtagtatga ttgtcacttg gttgggtgag
    56941 caaattacag ataagggata cggaaacggt gtttccatga ttatctttgc cgggattgtt
    57001 tcctcaattc cagagatgat tcagggcatc tatgtggact actttgtgaa cgtcccaagt
    57061 agccgtatca cttcatctat cattttcgta atcattttga ttattactgt attgttgatt
    57121 atttacttta caacttatgt tcaacaagca gaatacaaaa ttccaatcca atatactaag
    57181 gttgcacaag gtgctccatc tagctcttac cttccgttaa aggtaaaccc tgctggagtt
    57241 atccctgtta tctttgccag ttcgattact gcagcgcctg cggctattct tcagtttttg
    57301 agtgccacag gtcatgattg ggcttgggta agggtagcac aagagatgtt ggcaactact
    57361 tctccaactg gtattgccat gtatgctttg ttgattattc tctttacatt cttctatacg
    57421 tttgtacaga ttaatcctga aaaagcagca gagagcctac aaaagagtgg tgcctatatc
    57481 catggagttc gtcctggtaa aggtacagaa gaatatatgt ctaaacttct tcgtcgtctt
    57541 gcaactgttg gttccctctt ccttggtgtg atttccattt taccgattgc agctaaagat
    57601 gtatttggtc tttctgatgt tgttgccttt ggtggaacaa gtctcttgat cattatctct
    57661 acaggtatcg aaggaatcaa gcaattggaa ggttacctat tgaaacgtaa gtatgttggt
    57721 ttcatggaca gaacagaata aaagtattta ctgaatcagt aaatactgag ggagtggagg
    57781 tttaaactct gacatttgta agagttggat ctcccctctt ctattttgtt tttaaatagg
    57841 ggtgaaaaga ctttttgctt ctatttaaaa ataaaataag gagatcaaat catgaatctt
    57901 ttgattatgg gcttacctgg tgcaggtaag ggaactcaag cagcaaaaat cgtagaacaa
    57961 ttccatgttg cacatatctc aacaggtgat atgttccgcg ctgcaatggc aaatcaaact
    58021 gaaatgggtg ttcttgctaa gtcatatatt gacaagggtg aattggttcc tgacgaagtt
    58081 acaaatggaa tcgtaaaaga acgcctttca caagatgata ttaaagaaac aggattctta
    58141 ttggatggtt acccacgtac aattgaacaa gctcatgcct tggacaaaac attggctgaa
    58201 cttggcattg aactagaagg tattatcaat attgaagtga accctgacag cctcttggaa
    58261 cgtttgagtg gccgtatcat ccaccgcgta actggagaaa ctttccacaa ggtctttaac
    58321 ccaccagttg actataaaga agaagattac taccaacgtg aagatgataa gcctgagaca
    58381 gtaaaacgtc gtttggatgt taatattgct caaggagaac caatcattgc tcactaccgt
    58441 gccaaaggtt tggttcatga catcgaaggt aatcaagata tcaatgatgt cttctcagat
    58501 attgaaaaag tattgacaaa tttgaaataa agcgtttttc gcacttgcaa aaatccgcta
    58561 caaatgttat actgagatag tctgacttat aattgttgtc tctgtgtcta gaggcatcga
    58621 atcgaaattt atggaggtgc ttttgcgtgg caaaagacga tgtgattgaa gttgaaggca
    58681 aagtagttga tacaatgccg aatgcaatgt ttacggttga acttgaaaat ggacatcaga
    58741 ttttagcaac agtttctggt aaaattcgta aaaactatat tcgtatttta gcgggagatc
    58801 gtgttactgt cgaaatgagt ccatatgact tgacacgtgg acgtatcact taccgcttta
    58861 aataatcgaa aaacttggag ggataagaaa tgaaagtaag accatcggtc aaaccaattt
    58921 gcgaatactg taaagttatt cgtcgtaatg gtcgtgttat ggtaatttgc ccagcaaatc
    58981 caaaacacaa acaacgtcaa ggataagata gaaaggagaa aacatggctc gtattgctgg
    59041 agttgatatt ccaaatgaca aacgcgtagt aatctcattg acttatgttt atggtatcgg
    59101 acttgcaaca tctaagaaaa ttttggctgc tgctggaatc tcagaagatg ttcgtgtacg
    59161 tgatcttaca tcagatcaag aagatgctat ccgtcgtgaa gtggatgcaa tcaaagttga
    59221 aggtgacctt cgtcgtgaag taaacttgaa catcaaacgt ttgatggaaa tcggttcata
    59281 ccgtggtatc cgtcaccgtc gtggacttcc tgtccgtgga caaaacacta aaaacaacgc
    59341 tcgcactcgt aaaggtaaag ctgttgcgat tgctggtaag aaaaaataat ataggaggta
    59401 aaagtcttgg ctaaaccaac acgtaaacgt cgtgtgaaaa agaatatcga atctggtatt
    59461 gctcatattc acgctacatt taataacact attgttatga ttactgatgt gcatggtaat
    59521 gcaattgctt ggtcatcagc tggtgctctt ggtttcaaag gttctcgtaa atctacacca
    59581 ttcgctgctc aaatggcttc tgaagctgct gctaaatctg cacaagaaca cggtcttaaa
    59641 tcagttgaag ttactgtaaa aggtccaggt tctggtcgtg agtcagctat tcgtgcgctt
    59701 gctgccgctg gtcttgaagt aacagcaatt cgtgatgtga ctccagtgcc acacaatggt
    59761 gctcgtcctc caaaacgtcg ccgtgtataa tcatcgcatt acactgcttt tcgtttaaga
    59821 gggagtaact aaatgatcga gtttgaaaaa ccaaatataa caaaaattga tgaaaataaa
    59881 gattatggca agtttgtaat cgaaccactt gaacgtggct acggtacaac tcttggtaac
    59941 tctcttcgtc gtgtacttct agcttctcta ccaggagcag ctgtgacatc tatcaacatt
    60001 gatggtgtgt tacatgagtt tgacacagtt ccaggtgttc gtgaagacgt gatgcaaatc
    60061 attctgaaca ttaaaggaat tgcagtgaaa tcgtacgttg aagacgaaaa aatcatcgaa
    60121 ctggatgttg aaggtcctgc tgaagtaaca gctggtgaca ttttgacaga tagcgatatt
    60181 gaaattgtaa atccagatca ttatctcttt acaatcggtg aaggttcttc tctaaaagcg
    60241 actatgactg ttaacagtgg tcgtggatat gtacctgctg atgaaaataa aaaggataat
    60301 gcaccagttg gaacacttgc tgtagattct atttatacac cagttacaaa agtcaactat
    60361 caagtggaac ctgctcgtgt aggtagcaat gatggtttcg acaaattaac ccttgaaatc
    60421 ttgacaaatg gaacaattat tccagaagat gctttagggc tttcagcacg tattttgaca
    60481 gaacatcttg atttgtttac aaatcttact gagattgcta agtcaactga agtgatgaaa
    60541 gaagctgata ctgaatctga cgaccgtatt ttagatcgta cgattgagga actggacttg
    60601 tctgtgcgtt catacaactg tttaaaacgt gccggtatca atactgtgca tgatttgaca
    60661 gaaaaatctg aagcagagat gatgaaagta cgaaatcttg gacgcaagag tttggaagaa
    60721 gtgaaactca aactcattga tttgggtctt ggattaaaag ataaataaag gaggaataca
    60781 tggcttaccg taaactagga cgcactagct cacaacgtaa agcaatgctt cgcgatttga
    60841 caactgacct tttgatcaac gaatcaatcg tgacaactga agctcgtgct aaagaaatcc
    60901 gtaaaactgt tgaaaaaatg attactctag gtaaacgtgg tgatttgcat gcacgtcgtc
    60961 aagcagctgc tttcgtacgt aatgaaatcg catctgaaaa ctatgatgaa gcaactgata
    61021 agtacacttc tactacagca cttcaaaaat tgttctcaga aatcgcacct cgttatgctg
    61081 aacgtaacgg tggatacact cgtatcctta aaactgaacc acgtcgtggt gatgcagcgc
    61141 caatggcgat catcgaatta gtataaaatc atcaattttg ttgagtgtta tgatgatgga
    61201 gtcttgtgct cttagtctag ctctggtcta ccgctaggat ttcggtccta gcgggaacac
    61261 tcatcataag ttgggatagt agacgcttgt ttacgaaatt gtttttttct taagaacaac
    61321 ttcgtaagca ggcgtttttg agtattttcg ttagaattat gctatactat ttgaaaagaa
    61381 tcctgtttaa tgttaaggtt tcttatttta agaagaattg gagtttactt atgaaagcca
    61441 ttataactgt tgttggtaaa gataaatctg gaattgttgc aggtgtttct ggtaaaattg
    61501 cagaattagg attgaatatt gacgatatct ctcaaactgt cttggatgaa tattttacga
    61561 tgatggctgt tgtatctagt gatgaaaagc aagattttac ctatcttcgt aatgaatttg
    61621 aagcttttgg gcaaactttg aatgtaaaaa tcaatattca gagtgcagcg attttcgaag
    61681 ctatgtataa tatctaggag gttatcatgg atattagaca agttactgaa accatcgcca
    61741 tgattgagga gcaaaatttc gatatcagaa ccattaccat ggggatttct cttttggatt
    61801 gtatcgatcc agatatcaat cgtgctgcgg agaaaatcta tcaaaaaatt acgacaaagg
    61861 cggctaattt agtagctgtt ggtgatgaaa ttgcggctga gttgggaatt cctatcgtta
    61921 ataagcgtgt atcggtgaca cctatttctc tgattggggc agcgacagat gcgacggact
    61981 acgtggttct ggcaaaagcg cttgataagg ctgcgaaaga gattggtgtg gactttattg
    62041 gtggtttttc tgccttagta caaaaaggtt atcaaaaggg agatgagatt ctcatcaatt
    62101 ccattcctcg cgctttgact gagacggata aggtctgctc gtcagtcaat atcggctcaa
    62161 ccaagtctgg tattaatatg acggctgtgg cagatatggg acgaattatc aaggaaacgg
    62221 caaatctttc agatatggga gcggccaagt tggttgtatt cgctaatgct gttgaggaca
    62281 atccatttat ggcgggtgcc tttcatggtg ttggggaagc agatgttatc atcaatgtcg
    62341 gagtttctgg tcctggtgtg gtgaaacgtg ctttggaaaa agttcgtgga cagagctttg
    62401 atgtagtagc cgaaacagtt aagaaaactg cctttaaaat cactcgtatc ggtcaattgg
    62461 ttggtcaaat ggccagtgag agactgggtg tggagtttgg tattgtggac ttgagtttgg
    62521 caccaacccc tgcggttgga gactctgtgg cacgtgtcct tgaggaaatg gggctagaaa
    62581 cagttggcac gcatggaacg acagctgcct tggccctctt gaacgaccaa gttaaaaagg
    62641 gtggagtgat ggcctgtaat caggtcggtg gtctatctgg tgcctttatc cctgtttctg
    62701 aggatgaagg aatgattgct gcagtgcaaa atggctctct taatttagaa aaactagaag
    62761 ctatgacggc tatctgttct gttggattgg atatgattgc catcccagaa gatacgcctg
    62821 ctgaaactat tgcggctatg attgcggatg aagcagcaat cggtgttatc aacatgaaaa
    62881 caacagctgt tcgtatcatt cccaaaggaa gagaaggcga tatgattgag tttggtggtc
    62941 tattaggaac tgcacccgtt atgaaggtta atggggcttc gtctgtcgac ttcatctctc
    63001 gcggtggaca aatcccagca ccaattcata gttttaaaaa ttaagaaaat aggagaaatt
    63061 ttaagttcta tttaagatta gatgtgtata ctataatcat taaataaaga cctcctaata
    63121 ttatttgaaa cagataacac tgaattagtt tgaatttgat tttcatctaa tatctttatt
    63181 taatgaactc ctaaactttt tcataataat ctccttcaaa agtcgcctgt atgggtggct
    63241 tttattttat cattcatgat ataatagaag caaacggagg acggaaaatg gtaaaagtac
    63301 gattgtattt gatacgtcat ggcaagacca tgtttaacac gattggtcgc gcgcaaggtt
    63361 ggagcgatac tcccttaact gctgaaggtg aacgagggat tcaagagtta ggaattggtt
    63421 tgcgagaatc tgatctacag tttgagcgcg cttattcgag tgattctggt cgtaccattc
    63481 agaccatggg aattatcctt gaagaacttg gcttgcaggg gaaaatccct tatcgcatgg
    63541 acaagcgtat cagagaatgg tgtttcggta gttttgatgg agcctatgat ggcgatcttt
    63601 tcatgggcat tattcctcgt atctttaatg tggaccacgt tcaccaattg tcttatgctg
    63661 aactggctga gggcttggta gaggtcgata cagctggttg ggctgaaggc tgggaaaaac
    63721 tcagtggccg aatcaaggaa ggctttgaaa tgattgcaaa agaaatggaa gatcaaggtg
    63781 gaggtaacgc ccttgttgtc agccatggaa tgactattgg aaccattgtt tatctgatta
    63841 atggcatgca tccgcatggt ctagataatg gtagcgtgac gattcttgaa tatgaggacg
    63901 gtcagtttag ggttgaagtt gtcggtgacc gtagttaccg agagctagga cgtgagaaga
    63961 tggaagaagg ctctatttaa tcagtctaga cttgcttgcc atgagctagg gatttgataa
    64021 gaatatcaag ataagaaaaa acagccgagg gtactccttt cggctgtttt tgatgtggaa
    64081 aactaaagtg taatgctatt gcttttagag attttcataa acaagagcaa ggaacctact
    64141 gttagaacag tcaggatagt tgacaaggct gcggctacac cgtaatttcc tctgagaacc
    64201 tctgtataaa tagctacagt cattgttctt gttttgacat tgtagaggag gatagaagta
    64261 gagagttctg aaatcagtgt gacccaagat aggatggctc cagaaataat atccgatagc
    64321 atcattggag ttgtaatctt agcaaagata ttgagacgac tacttcctaa gctttcagca
    64381 gcttcttcaa tacttggtgc tatttgttgt aagctagcaa cagatgagcg aatagtataa
    64441 ggtaattttc tggcagatag agacataatc aagatgaaag cagtccctgt aatcataaga
    64501 aatccacttc caaatagacc agagaaatga aggcaatccc tagaacggtt cctggtacaa
    64561 tataaggtac catactgagg ctgtcaatta agtttgtaaa caaattccgt tttctaacgg
    64621 ctaggtagga gataaatgtc gcaaatagaa caactagaac taaggcaatc aaagggatac
    64681 gaatggtatt gaaaatagca gatcccatac gatggaaagc taccttgtaa ctgtttggag
    64741 aataaccttt aacagatacc atacctgatg tttttaggaa agaggtataa attaagtaga
    64801 tttgaggtaa aacagagata aagataattc cgtagactgt tgcataaatg gcagctattt
    64861 ttccttttgt agttttttta ggctcaattg gatggagcag attcatgctg aaactgtagc
    64921 ggtttgcaat gtgtttttgg ataaggaaaa ttgccaaggc aatgataatc gccataattg
    64981 caaaagcaga atttcctcca acctcgctaa taaattgggt ataaatcagg acagggaaag
    65041 tccgatatcc ttcgccaatc aacataggcg ttccaaagtc tgagaatgct ctcataaata
    65101 caagcaagga gctgctagta aggttggaac taggagaggt aaaacaaccg ttacgatacg
    65161 cttaaatccg aaggaccccc atgctttcag ctgcttcaag tagagaattg tcaatactgt
    65221 tcattgttcc agcaacatat agaaatacca gtgggaatag ttgcagtgta aagacaagta
    65281 caattccttt gaatccataa atatcgatag ctggaagatg aagggcattt gtcaaaaatt
    65341 tagtgatgac cccatttcgt cctagcaaga gaacccagga gtaggctcct acgaaaggag
    65401 ctgacatgga agcaatgata atcaatattt gtagaaattt ctcccccttg aagtcataca
    65461 tagagaagag ataagctaat agggttccta caactaagga agtgacagta gcggtaatgg
    65521 aaaccttgaa actgttgact agtgtctcag agtagtagac tttactaaag aaagtgacaa
    65581 aattagctag tgagaattat ccttcatgta taagtgctta cttgagcacg gtaatgatag
    65641 gataaacgag aaagacaaga taggtaagaa agatgaagaa agaggaggct gtccaaatat
    65701 ttagtttttt acattccatg gttgactcct tttatcaggt tttgggaacc atctgcagaa
    65761 aagatgttta atttttgcgt attgattcgt agacgaatac gattgtcttt ttgtagatct
    65821 tcttcaaaag ttgattcttc actaacttga atttttgagg caaaacctgt ctcaatgaaa
    65881 tactccgtat ttagtccaag atagacgcta tcgctaatag ttccttcaat atctccagat
    65941 tcatctttga taaactcttc gggacgaatg cttacatgaa tagcttgctc ctcaacctga
    66001 tcaagagctg gcattcgaag ggcatagcca tctgaaaaga cgatataagc gccgtcgctc
    66061 cgtttttcaa gattggcagg gataatattt gtgcgtccga taaaggttgc cacaaactca
    66121 ttagctggtt tatgatagag ttcttttggt cggccgattt gttggatcac cccatctttc
    66181 ataacagcaa tttgatctga aatagccatg gcttcttctt ggtcgtgggt tacataaaca
    66241 gttgtaattc ccacttcgtg ttggatttct cggatggctt gacgcatatc caagcgaagt
    66301 ttggcctcca gattactaag tggctcgtcc atgaggagaa cacttggatt aaccgctaag
    66361 gcgcatgcca aggtgacacg ttgttgttgt ccaccactga gtttatcggg ctttcgatcc
    66421 gcatattgag caatttgcat gagttcaaga tacttgttgg tctgttgaat caattcttct
    66481 tttggaacct tcttttgctt aagaccaaaa gcaacgttgt ctcggacagt caaatgtggg
    66541 aaaatagcgt agttttggaa aaccatcccg atattgcgtt tgctgggttc catattattg
    66601 atttttgtat catcgaagta aaattctcca tctttgatac tgttgaaacc tgcaatcata
    66661 cgaagaaggg tcgttttccc acatcctgaa ggtccaagaa gggtaaagag acttcctttt
    66721 ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt ggtagatttt ttggcgttaa
    66781 taattttgat ctcactcata gtgaaccttt tttactgttt agattggata tctgtaaaga
    66841 cttcgttgta tttcttaacg atatctgatt tattcttgat gacataatca taatcttcag
    66901 tgagtgtttt gattttgtca attggtttca tgttttcgct tgttttagca tttttacgaa
    66961 caggacggtt agtagtggtt gtaccaagtg tatcttgtac ttcttgagag ataataaaat
    67021 cgataaattt cttgtcattt tccatatttt tagctttttt aacgatagca gcactagcag
    67081 gtaggaagac ggttccttct tttggataga ctactttaat gttagctccg tcatttaaga
    67141 gtttaactgc tggatcctca taagagagac caacagccat ttctccatca acgactgctt
    67201 tatagacacc agatgaactt gaaccgattt tatagtgtat tgaaactaga atagtacacc
    67261 tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgattaattt gtcctgttct
    67321 tatttcattt cactatgcca tcaataagtg tgaaaagatc ttttacataa gaccaagcct
    67381 tatcatcttt gtaaccacct tgagcttgta gcatatttgt taattgagca aaggcgctag
    67441 aagagtttgc tgggtcagca gttgcgattt ttccttttag ttcaggtttg agaaggtcgc
    67501 tatatccttc gatgttcatg cctttagtta aatcagggtt gacgattaaa acactaccat
    67561 ctagtgtata aggagtagag aagccagttg tgttttgata ttctttgata acattatcat
    67621 tttcttttga aatatagttt tcaaagagtt ctccgtgggt agcatattgt gtataagaac
    67681 caccaaagat aacatcagct acaggaactt ctttttctga ctctagtttt ttgaaaagtt
    67741 ctccagtacc agcttgaatc agttctattt tgataccata tttttcttca aaggcaggaa
    67801 tagttgctcc aattaagcct tctgagtttg gtgaataaac gactagcgaa ccaccgtctc
    67861 ctttatcaga tgaactgtca tcggcagatt cattagaaga acaagcagca taatacatct
    67921 atttcttttt catgatggat atctccgttg tgttatttaa gtttatttta aaacaatgta
    67981 agcgttttta aaacctacaa ttctattcta tagtgtattg aatctataac ag
//
LOCUS       DAVLAQ010000004        59475 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000004 DAVLAQ010000000
VERSION     DAVLAQ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.004"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(68..1048)
                     /gene="dusB"
                     /locus_tag="VXB71_000240"
     CDS             complement(68..1048)
                     /gene="dusB"
                     /locus_tag="VXB71_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0450418.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1035..1907)
                     /gene="hslO"
                     /locus_tag="VXB71_000241"
     CDS             complement(1035..1907)
                     /gene="hslO"
                     /locus_tag="VXB71_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0450419.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2072..3499
                     /locus_tag="VXB71_000242"
     CDS             2072..3499
                     /locus_tag="VXB71_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0450420.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3658..5166
                     /gene="glpK"
                     /locus_tag="VXB71_000243"
     CDS             3658..5166
                     /gene="glpK"
                     /locus_tag="VXB71_000243"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0450421.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNFVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5208..7034
                     /gene="glpO"
                     /locus_tag="VXB71_000244"
     CDS             5208..7034
                     /gene="glpO"
                     /locus_tag="VXB71_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0450422.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7104..7808
                     /locus_tag="VXB71_000245"
     CDS             7104..7808
                     /locus_tag="VXB71_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0450423.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8105..8308
                     /locus_tag="VXB71_000246"
     CDS             8105..8308
                     /locus_tag="VXB71_000246"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450424.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8395..9003)
                     /locus_tag="VXB71_000247"
     CDS             complement(8395..9003)
                     /locus_tag="VXB71_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450425.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10137..11414
                     /gene="ltrA"
                     /locus_tag="VXB71_000248"
     CDS             10137..11414
                     /gene="ltrA"
                     /locus_tag="VXB71_000248"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0450426.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGISTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVVSEAAAKRMMYSVSRFIEKRLGLKANMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            11870..13048
                     /locus_tag="VXB71_000249"
     CDS             11870..13048
                     /locus_tag="VXB71_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0450427.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13362..13493
                     /locus_tag="VXB71_000250"
     CDS             13362..13493
                     /locus_tag="VXB71_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0450428.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13514..15064
                     /gene="dltA"
                     /locus_tag="VXB71_000251"
     CDS             13514..15064
                     /gene="dltA"
                     /locus_tag="VXB71_000251"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0450429.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNAHIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFENLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15061..16305
                     /gene="dltB"
                     /locus_tag="VXB71_000252"
     CDS             15061..16305
                     /gene="dltB"
                     /locus_tag="VXB71_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0450430.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16319..16558
                     /gene="dltC"
                     /locus_tag="VXB71_000253"
     CDS             16319..16558
                     /gene="dltC"
                     /locus_tag="VXB71_000253"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0450431.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16551..17819
                     /gene="dltD"
                     /locus_tag="VXB71_000254"
     CDS             16551..17819
                     /gene="dltD"
                     /locus_tag="VXB71_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0450432.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLQQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            17974..18414
                     /gene="adcR"
                     /locus_tag="VXB71_000255"
     CDS             17974..18414
                     /gene="adcR"
                     /locus_tag="VXB71_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0450433.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18414..19118
                     /locus_tag="VXB71_000256"
     CDS             18414..19118
                     /locus_tag="VXB71_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0450434.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19111..19917
                     /locus_tag="VXB71_000257"
     CDS             19111..19917
                     /locus_tag="VXB71_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0450435.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            19927..21432
                     /gene="adcA"
                     /locus_tag="VXB71_000258"
     CDS             19927..21432
                     /gene="adcA"
                     /locus_tag="VXB71_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0450436.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYTEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22603..23376)
                     /locus_tag="VXB71_000259"
     CDS             complement(22603..23376)
                     /locus_tag="VXB71_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0450437.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23552..24955
                     /locus_tag="VXB71_000260"
     CDS             23552..24955
                     /locus_tag="VXB71_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0450438.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25070..25708
                     /locus_tag="VXB71_000261"
     CDS             25070..25708
                     /locus_tag="VXB71_000261"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0450439.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25720..26160
                     /locus_tag="VXB71_000262"
     CDS             25720..26160
                     /locus_tag="VXB71_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0450440.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26153..26584
                     /locus_tag="VXB71_000263"
     CDS             26153..26584
                     /locus_tag="VXB71_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0450441.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26575..27045
                     /locus_tag="VXB71_000264"
     CDS             26575..27045
                     /locus_tag="VXB71_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0450442.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27070..27843
                     /locus_tag="VXB71_000265"
     CDS             27070..27843
                     /locus_tag="VXB71_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0450443.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27840..28640
                     /locus_tag="VXB71_000266"
     CDS             27840..28640
                     /locus_tag="VXB71_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0450444.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28699..30993
                     /locus_tag="VXB71_000267"
     CDS             28699..30993
                     /locus_tag="VXB71_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0450445.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31003..34119
                     /locus_tag="VXB71_000268"
     CDS             31003..34119
                     /locus_tag="VXB71_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0450446.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34176..35942
                     /locus_tag="VXB71_000269"
     CDS             34176..35942
                     /locus_tag="VXB71_000269"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0450447.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36088..37239
                     /locus_tag="VXB71_000270"
     CDS             36088..37239
                     /locus_tag="VXB71_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0450448.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37384..38268
                     /locus_tag="VXB71_000271"
     CDS             37384..38268
                     /locus_tag="VXB71_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0450449.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(38386..38463)
                     /locus_tag="VXB71_000272"
                     /pseudo
     CDS             complement(38386..38463)
                     /locus_tag="VXB71_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            38667..38918
                     /locus_tag="VXB71_000273"
     CDS             38667..38918
                     /locus_tag="VXB71_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0450450.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            38906..39196
                     /locus_tag="VXB71_000274"
     CDS             38906..39196
                     /locus_tag="VXB71_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450451.1"
                     /translation="MGALGYYEGFVPYVSNQYQNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(39601..40932)
                     /locus_tag="VXB71_000275"
     CDS             complement(39601..40932)
                     /locus_tag="VXB71_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0450452.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(40954..42465)
                     /locus_tag="VXB71_000276"
     CDS             complement(40954..42465)
                     /locus_tag="VXB71_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0450453.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42676..43623)
                     /gene="arcC"
                     /locus_tag="VXB71_000277"
     CDS             complement(42676..43623)
                     /gene="arcC"
                     /locus_tag="VXB71_000277"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0450454.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(43788..44804)
                     /gene="argF"
                     /locus_tag="VXB71_000278"
     CDS             complement(43788..44804)
                     /gene="argF"
                     /locus_tag="VXB71_000278"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0450455.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(44862..46091)
                     /gene="arcA"
                     /locus_tag="VXB71_000279"
     CDS             complement(44862..46091)
                     /gene="arcA"
                     /locus_tag="VXB71_000279"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0450456.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            46847..48526
                     /locus_tag="VXB71_000280"
     CDS             46847..48526
                     /locus_tag="VXB71_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0450457.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLYFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48566..50650)
                     /locus_tag="VXB71_000281"
     CDS             complement(48566..50650)
                     /locus_tag="VXB71_000281"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0450458.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            50821..52101
                     /locus_tag="VXB71_000282"
     CDS             50821..52101
                     /locus_tag="VXB71_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0450459.1"
                     /translation="MIYPKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52192..54837
                     /locus_tag="VXB71_000283"
     CDS             52192..54837
                     /locus_tag="VXB71_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0450460.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            54921..55790
                     /locus_tag="VXB71_000284"
     CDS             54921..55790
                     /locus_tag="VXB71_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0450461.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            55784..57664
                     /locus_tag="VXB71_000285"
     CDS             55784..57664
                     /locus_tag="VXB71_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0450462.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58042..58404
                     /locus_tag="VXB71_000286"
     CDS             58042..58404
                     /locus_tag="VXB71_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450463.1"
                     /translation="MPKTKTLAELADVILWGFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(58474..59185)
                     /locus_tag="VXB71_000287"
                     /pseudo
     CDS             complement(58474..59185)
                     /locus_tag="VXB71_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(59130..59312)
                     /locus_tag="VXB71_000288"
     CDS             complement(59130..59312)
                     /locus_tag="VXB71_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0450464.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
BASE COUNT        17923 a        10894 c        13046 g        17612 t
ORIGIN      
        1 tttttttgat gaggaaagaa tggcggcact caagagactc tttaagagag ttacgggttt
       61 taaactatta agccttctcc aattgcaaga gagcttcaat ctctgccagg gtgctagctt
      121 gcgaaatggc tccacggagt ttggcagcgc cagatgttcc acggaggtag tgaggagcga
      181 ggccacggaa ttcacgaact gcgacgtttt ctcctttgag gttaatcaat cgtttcaagt
      241 gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc aggtaggatt tctcctgttt
      301 caaagtaatg gttgatttgg ttgaagaggt aaggatttcc catggcagct cggccaatca
      361 tgactgcgtc agcaccaact tcttcgatgc gttgcttggc ttcttggaca gtacggatat
      421 caccgttggc gatgaatgga atcttggtta gagcttgggc aaccttgtac agggtctcaa
      481 ggtctgcgtg gccagtatac atttgttcac gggtacggcc atgcatggcg agggcagaaa
      541 cacctgcagc ctcagcagcg agggcatttt ctactgccag agatgggtcc gcccagccgg
      601 tacgcatttt gacagtaagt gggatatcaa ggacagactg gaccttgttg atgatagagt
      661 agatcttgtc aggatccttg agccacatag ctccagcttc gttcttcacg attttgttga
      721 cagggcagcc catgttgata tcgacgatat cggtcttggt gttttcttgg atgaattctg
      781 ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg gatagagaca gggttttcgc
      841 cctcatcgat atgaagcatg tgcagggttt tttcgttgtt gtattggatt cccttgtcag
      901 agaccatttc cattacaacg agtccagctc cgagctcttt tgcgatggta cgaaaggctg
      961 agttggtcac gccagccata ggcgctaaaa cggtacgatt gggaatctca acattgccaa
     1021 tcataaaagg tgtattaaga tttgtcacga atgagttcct ccaggtcctt ttcatcaaag
     1081 ttgtaagtag tttggcagaa ttgacaagtg atttctaccc cgtggtcttc ctctttcatt
     1141 tcctgtaagt ctgagcttgg aaggctggca agagcgttca taaagcgttc atggctacag
     1201 tcacattgga aacggatttc ttcttcagaa agacgcttgt aggcttcgtc cccgtagata
     1261 gccttgagga gggcttcgat atggtcgtcg ctttcgagaa gagtagagat agctggcatt
     1321 tcttggatgc gtttttcaaa gcgagcaatc tcttctttct tggctcctgg caagacttga
     1381 actaggaaac cacctgcaac cttgaccttg tcttcctcgt ccaaaaggac attgaggccg
     1441 accgctgaag gcgtttgttg gctttcagta aggtaaaagg caaggtcttc accgatttct
     1501 ccagagatga ggggagttat agagttgtaa ggatttccag caccgtagtc tgtgataacg
     1561 aggaattgac catttccaac aaaaggtccg actaggactt caccagtcgc agtctttttg
     1621 atgtcaacac caggattttg aacatagcct ttgacgttcc ccttggtatc agcgacggtg
     1681 ataatagcac ctagagagct agagcccaac accttaactg taagtttggt atttcctttt
     1741 tcattggctg cgagaatctg gctggcgata agagttcgac caagcgctac agttgagcta
     1801 gcttgggttt gatgtttttc ttgagcagtg cggacggttt ccgtgctatc aaggacaaaa
     1861 gcacgaaagg ctccgctttc tgatatagtt ttaataattt tatccatagc tactatttta
     1921 gcataaaaat gcccaaaggg ggagccgtgt gtttactgat tttcaggata atggaccagg
     1981 aaatcagcat gaaaataaaa agagaaacag attattttag catttgtaag atttatgcta
     2041 tgcttaaggt agaaaatgaa aggggtaaca aatgtattta ggagatttga tggagaaagc
     2101 cgagtgtggt caattttcaa tcctttcctt tctattacaa gagtctcaga cgaccgtcaa
     2161 ggctgtaatg gaagaaacag gattttcaaa agcaacccta accaaatatg tcaccctgct
     2221 caatgacaag gctttggata gtggcttaga gctggctatt cactcagaag atgaaaatct
     2281 gcgtctgtct atcggtgcag ctaccaaggg gagagatatt cggagcttgt ttttggagag
     2341 tgctgttaaa taccagattt tggtttatct tctctaccac caacagtttt tagcccatca
     2401 gctggctcaa gaattggtga ttagcgaggc tacgcttggt cgtcacttgg ctggtttaaa
     2461 tcagattttg tcagaatttg atttatccat ccaaaatgga cgttggcgag gtccagagca
     2521 tcagattcgc tatttctatt tctgtctttt ccgaaaggtc tggtcgagtc aggaatggga
     2581 aggtcacatg cagaaaccag agagaaaaca ggagattgcc aatttagagg aaatctgcgg
     2641 tgcaagtttg tctgtggggc agaaattgga cttggttctc tgggctcaca tcagtcaaca
     2701 acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa gagaaaatgc gagggtattt
     2761 tgacaatatt ttctaccttc gtttgctgag aaaggttccg tccttttttg ctgggcaaca
     2821 tattccacta ggagttgagg atggtgagat gatgatattc ttctcttttc tcctatctca
     2881 tcgcattctt cctcttcata ctatggagta tattcttggt tttggagggc agttggcaga
     2941 tttactgacg caattgattc aagaaatgaa gaaggaggaa ctattggggg attatacaga
     3001 ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa gtctatctct ataagggcta
     3061 tattttacag gatcgctaca agtaccagtt agagaatcgt catccatatt tactgatgga
     3121 acatgatttt aaagagacag cagaggagat ttttcatgct ctacctgctt ttcaacaggg
     3181 gacagattta gataagaaga ttctctggga atggctccag ttaatcgaat atatggctga
     3241 aaacggtggc cagcatatgc ggattggtct ggatttgaca tctggttttc ttgtcttttc
     3301 aaggatggca gccattttga aacggtattt ggaatacaat cgttttatta ccattgaagc
     3361 ctatgaccct agtcggcatt atgatttgct ggttaccaat aacccgattc ataagaagga
     3421 acagacacca gtctattatt taaaaaatga cttggatatg gaggatttgg tagcgattcg
     3481 ccagttatta ttcacttaaa aggcttggtt aatccaggtc ttttttgtga aattcacaca
     3541 atctcctcac atttttttaa aaattaaaaa aagttgataa acaagaaagc gctttatttt
     3601 gtatactagt aagtgtaaag aggaaacacc tcaagatctt tatcaggagg acagtacatg
     3661 tcacaagaaa aatacatcat ggccattgac cagggaacta caagttctcg tgccatcatt
     3721 ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag agtttaccca gattttccct
     3781 caggcaggtt gggttgagca caatgccaat gaaatttgga actttgttca gtcagttatt
     3841 gcgggtgctt tcatcgaaag tggtgtcaag ccaaatcaaa tcgaggcaat cgggattacc
     3901 aaccaacgtg aaacaacggt tgtctgggat aagaaaacag gacttcctat ctacaatgct
     3961 atcgtttggc agtcacgcca gacagcacct ttggctgagc aactaaaaag ccaaggttat
     4021 gtggaaaaat tccatgaaaa gactggtttg attattgatg cttacttctc tgctaccaag
     4081 gttcgttgga ttttggatca tgtagaaggt gctcaagagc gagcagaaaa aggggaattg
     4141 ctctttggta ctatcgatac ttggttggtt tggaaattga ctgacggtgc ggctcacgtg
     4201 actgactact caaatgcagc tcgtaccatg ctttataaca ttaaagaact caaatgggat
     4261 gatgagattt tggaaatcct taacattccg aaggctatac ttccagaagt tcgttctaac
     4321 tccgaaatct acggcaagac agctccattc catttctacg gtggagaggt gccaatctca
     4381 ggtatggctg gggaccaaca agcagccctc tttggacagt tggcttttga gccaggtatg
     4441 gttaagaata cttatggaac aggctctttc atcatcatga atactgggga agagatgcag
     4501 ttgtctgaaa acaacctctt gacaaccatt ggttacggaa tcaacggtaa ggtttattat
     4561 gccttggaag gttctatctt catcgcagga agtgctattc agtggcttcg tgacggtctt
     4621 cgcatggttg aaaattcacc agaatctgaa aaatacgctc gtgattctca caacaacgat
     4681 gaagtttatg tcgttccagc ctttacaggt ctaggcgctc catactggaa ccaaaatgct
     4741 cgtggttccg tctttggttt gactcgtgga acaagcaaag aagactttat caaggcgact
     4801 ttgcaatcta ttgcttatca agtgcgtgat atcatcgaca ccatgcaagt ggatactcag
     4861 accgccattc aagtactgaa ggtggatggt ggtgcagcca tgaacaactt cctcatgcag
     4921 ttccaggcgg atattttagg cattgacatt gcacgtgcta aaaacttgga aacaacagct
     4981 ctaggagcgg ccttcctagc aggtttgtca gtagggtact ggaaagactt ggacgagttg
     5041 aaactcttga acgagacagg agaactcttt gagccatcta tgaacgaatc tcgcaaggaa
     5101 caactctaca agggctggaa gaaggctgtg aaagcaactc aagtctttgc ggaagtagac
     5161 gactaatact ggcagaataa agcgatttat ttagaaagtg tgtaaatatg gaattttcaa
     5221 aaaaaacacg tgaattgtca attaaaaaaa tgcaggaacg caccctggac ctcttgatta
     5281 tcggtggagg aatcacagga gctggtgtag ccttgcaggc ggcagctagc ggtcttgaga
     5341 ctggtttgat tgaaatgcaa gactttgcag aaggaacatc tagtcgttca acaaaattgg
     5401 ttcacggagg tcttcgctac ctcaaacaat tcgacgtaga agtggtctca gatacggttt
     5461 ctgaacgtgc agtggttcaa caaatcgctc cacacattcc aaaaccagat ccaatgctct
     5521 taccagttta cgatgaagat ggagcaacct ttagcctctt ccgtcttaaa gtagccatgg
     5581 acttgtacga cctcttggca ggtgttagca acacaccaac tgcgaacaag gttttgagca
     5641 agaaagaagt cttggaacgc cagccaaact tgaagaagga aggcttggta ggaggtggag
     5701 tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat tgaaaacatc aaacgtgcca
     5761 accaagacgg tgccctcatt gccaaccacg tgaaggcaga aggcttcctc tttgacgaaa
     5821 gtggcaagat tacaggtgtt gtagctcgtg atctcttgac agatcaagta tttgaaatca
     5881 aggcccgtct ggttattaat acaacaggtc cttggagtga taaagtacgt aatttgtcta
     5941 ataagggaac gcaattctca caaatgcgcc caactaaggg agttcacttg gtagtggatt
     6001 caagcaaaat caaggtttca cagccagttt acttcgacac aggtttgggt gacggtcgta
     6061 tggtctttgt tctcccacgt gaaaacaaga cttactttgg tacaactgat acagactaca
     6121 caggtgattt ggagcatcca aaagtaactc aagaagatgt agattatcta cttggcattg
     6181 tcaacaaccg ctttccagaa tccaacatca ccattgatga tatcgaaagc agctgggcag
     6241 gtcttcgtcc attgattgca gggaacagtg cctctgacta taatggtgga aataacggta
     6301 ccatcagtga tgaaagcttt gacaacttga ttgcgactgt tgaatcttat ctctccaaag
     6361 aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct tgaaagtagc acatctgaga
     6421 aatatttgga tccatctgca gtttctcgtg ggtctagctt ggaccgtgat gacaatggtc
     6481 ttttgactct tgctggcggt aaaatcacag actaccgtaa gatggctgaa ggagctatgg
     6541 agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag ctttaaattg atcaattcta
     6601 aaacttaccc tgtttcaggt ggagaattga acccagcaaa tgtggattca gaaatcgaag
     6661 cctttgcgca acttggagta tcacgtggtt tggatagcaa ggaagctcac tatctggcaa
     6721 atctttacgg ttcaaatgca ccgaaggtct ttgcacttgc tcacagcttg gaacaagcgc
     6781 caggactcag cttggcagat accttgtccc ttcactatgc aatgcgcaac gagttggctc
     6841 ttagcccagt tgacttcctt cttcgtcgta ccaaccatat gctctttatg cgtgatagct
     6901 tggatagcat cgttgagcca gttttggatg aaatgggacg attctatgac tggacagaag
     6961 aagaaaaagc aacttaccgt gctgatgtcg aagcagctct cgctaacaac gatttagcag
     7021 aattaaaaaa ttaagaaaaa ataaaagagg tggagggcag cattccttgt cgcccgtccc
     7081 ttctttttaa tggagacaga aagatgatga atgaattatt tggagaattt ctagggactt
     7141 taatcctgat tcttctagga aatggtgttg ttgcaggtgt ggttcttcct aaaaccaaga
     7201 gcaatagctc aggttggatt gtgattacta tgggttgggg gattgcagtt gcggttgcag
     7261 tctttgtatc tggcaagctc agtccagctc atttaaatcc agctgtgaca gttggtgtag
     7321 ctttaaaagg tgacttgcct tgggcttccg ttttgcctta tatcttagcc cagttcgcag
     7381 gggccatgtt gggtcagatt ttggtttggt tgcaattcaa acctcactat gaggcagaag
     7441 aaaatgcagg caatatcctg gcaaccttca gtactggacc agccatcaag gatactgtat
     7501 caaacttgat tagcgaaatc cttggaacct ttgttttggt gttgacaatc tttgctttgg
     7561 gtctttacga ttttcaggca ggtatcggaa cctttgcagt gggaactttg attgtcggta
     7621 tcggtctatc actaggtggg acaacaggtt atgccttgaa cccagctcgt gaccttggac
     7681 ctcgtatcat gcacagcatc ttgccaattc caaacaaggg agacggagac tggtcttacg
     7741 cttggattcc tgttgtaggc cctgttatcg gagcagcctt ggcagtgctt gtattctcac
     7801 ttttctagtt tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
     7861 ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattttcatt gagtattaga
     7921 aaacaattat gttgatagag cttgggcaag agcccaattt cagcaaaaaa tgaagtaaat
     7981 cttctcataa taaaacgcat catatcaagc acgaaaattc cacgaggtca actacagtca
     8041 gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc aaaaagcaag cacctgcaag
     8101 caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa ttagacccaa aaatcgttga
     8161 tatgctagta gaatttcaca agtcacaagg cactttggaa actcccgagg cgcaagcaga
     8221 aatcgcccaa aaacgtgaag aaatcgagca aaggagagct gagcttgagg ataaaaaaca
     8281 agagcttttg aaccgcttga acaaatagag tttcgcaagt attatgctta caaattactt
     8341 gagcaattaa ctaaaatata aaccctgcct agatataaag gcagggttta tattttagaa
     8401 attcacgtag gttgttacgg tttttacata cccagtatag tttgagtttc tatagtattc
     8461 agtgataaac ttccattttc tttgagcaac atggatataa gtacttgtta tgtagtatgg
     8521 atatgggctt tgtgaatcca agtaagactg ataagcttgt ataccaaaat atgctccacc
     8581 aattattgca ccccatggac cccccaataa agcacctatc ctaccaatca tataactgat
     8641 tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat gtattgtgtt
     8701 gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt cgatttcatt
     8761 cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac gtcgttcaat
     8821 agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta aaatatttac
     8881 ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac cagatacaac
     8941 tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg aaatgctaga
     9001 catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag acataacgga
     9061 aactcttttg tatttttgat ttttttcaac ttttattata caataaaacc aaataaaaag
     9121 aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt ttgatcgtta
     9181 tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat ttagacacag
     9241 aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca ttcgcttggg
     9301 tctgctctac aataaaaaat aaatagacgt attttcaaaa aaaaaaaaat gaatatttat
     9361 attagcaaaa tgacgattta aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat
     9421 ctgaggtgta agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc
     9481 ctgactatcg tgaggtagcg gattaaaacg gtctggggat agaccgtttt aagtctgacg
     9541 caggaaataa gaatcgtcag aggaagggat agcgaaatcg tggctctacg aacaggaacg
     9601 tgatagtaag gcgtatatag cggataagga ggcttcaaac tctaaagtcc aaaaaggtag
     9661 tcgtaaccta tatgtgtaaa tcacgagagt aattgaattc ggactaaggt ttgtgtgaaa
     9721 aagataaatc tttctagagt ctaaagactc tgcgtcagat ttcctatttt cactgtaacc
     9781 ttttaacgtc ctcatatctt gtataaacga ggaaagatgt acgacttatc ccgtgaggtt
     9841 tcatgagcgc tgaaagcgta gtaacaacga atcatgagaa gtcagccgag cccatagtag
     9901 tgaggaaact tctgtagtgg aagtggagcg aaggggtgaa tactcaaaca gtctggggag
     9961 agactgtttg aggtctgtcg ctagaaagag aaaacgacag atcgaagtaa tcctacttca
    10021 cttgtgtctg taaaatgagt ggtctgatag aactggactt tgacacgtaa tgactagatg
    10081 aaggttcacc aatataagat gtccctcagg caccaaaaca agaaaggaat acgcacatgt
    10141 caaaactgct agataagata ttatcacgcg aaaatatgct ggaagcctac aatcaagtaa
    10201 aatccaataa aggctcagct gggattgatg gaatgactat cgaagagatg gataattatc
    10261 tcagacaaaa ctggcgcttg actaaggaac tgataaaaca gagaaaatat aagcctcaac
    10321 cagttcttaa agttgagata cctaaaccag acggaggcat ccgtcaacta ggaatctcaa
    10381 cagttatgga tagaatgatt caacaggcca ttgtccaagt catgagcccc atttgtgaac
    10441 cccatttctc agatacgagt tatggtttca gaccaaatag gtcatgtgaa aaagccatca
    10501 tgaagctctt agaatactta aatgacggct atgagtggat agtggatata gacctagaga
    10561 aatttttcga tacagttcct caagatagat tgatgtcctt agtacataac attatcgaag
    10621 acggagatac ggaatccttg attcgtaagt atcttcattc aggtgttatc attaatggtc
    10681 aacgttataa aacactagtt ggtacaccac agggaggaaa tttatctcct ctcttatcca
    10741 atatcatgct taatgaattg gacaaggaat tagaaaagag gggacttcga tttgtgcgct
    10801 acgcagatga ttgtgtgatt acggtcgtaa gcgaggcagc cgctaagcgt atgatgtatt
    10861 cagtcagtcg ttttattgaa aaacggctag gtttgaaagc aaacatgacc aagactaaga
    10921 ttaccagacc aagagagttg aaatatctag gttttgggtt ctggaaatca tcagatggtt
    10981 ggaaaagtcg tccacatcaa gatagtgttc ggagatttaa gcttaaattg aagaaactaa
    11041 cacagaggaa atggagtata gacctaacaa gacgtattga gcaactgaat ttgtctattc
    11101 gaggatggat aaactatttc tcattgggaa atatgaaaag tatagtcgcc agcatagatg
    11161 agcgcttgcg tactcgccta cgagtgatta tctggaagca atggaagaag aaatcgagac
    11221 gattatgggg attgcttaag ttaggggttc ctaaatggat agcagataag gtatctggct
    11281 ggggcgacca ttatcaatta gtagctcaga agtcggtact taaacgtgct atatcaaaac
    11341 cagtcctgga aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt
    11401 taaaagttag ttgaaccgct gtatgccgaa cggcacgtac ggtggtgtga gaggggctag
    11461 agattatccc ctactcgatt aactcccctg aaatttattt taattatgca aatttcacgt
    11521 atttttgatg ctgagacgac gatcctggga acttttcaga tatttttttg actatctaaa
    11581 tctatcatta gaaaagctta gagcgccaaa ggatttgagc gtttttctga tttttaagac
    11641 tttttccagt ctctttttcg attgaagatg taattattct actaactaac taacttctta
    11701 gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata aaggcaatag
    11761 tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat gctaaaatat
    11821 taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca tgtctaattc
    11881 atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt tctttagagt
    11941 aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat cactagttcc
    12001 tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg ttactaaaag
    12061 gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat tattggcgat
    12121 actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct atctatttgt
    12181 tgttgcaatt tccatactag atggttttgc agcacctgtt tcctatgcta ttgtgccacg
    12241 ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg aagctgttca
    12301 attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt tacctaccac
    12361 gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc ttcctaacgc
    12421 tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag gttggaagtt
    12481 agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg aaattttttc
    12541 aaatacgatt tgggtttctt ccattatact tgtttttgta acggagttat taaataaaac
    12601 ggaaagttac tggggatatt ctaatacagc atactctatt ggtattataa ttagtggctt
    12661 aattgctttt aggctatctg aaaagttcct tgctgctaaa tgggaaagta ttctttttcc
    12721 tcttgtagct atggcaatag tgacactgac tattctatat tttccaaacg cacagatgtt
    12781 tttattattt tcagctttag ttggtatgtt atcgcaacta aaagaagttc ctgaaagtgt
    12841 atttcttcag gaaacagtag aggaaaatca tttagttaat gtctattccg ttcttgaagt
    12901 gatttctaca ttagcatttt cagtatttgt tttgctaatg agctatatta ctgagagttt
    12961 tggtattagc atcagttttt ggctatcagc catttgtctg atgatagaag ctattttaat
    13021 ttatatcaga cgagattatt ttaaatgaga gagtggttaa aaagtcttta aaaatcagaa
    13081 aagcgcatag tatcaggtgt tgaaaaaact tgatattgtg tgttttatta tgggaagatt
    13141 tacttcattg tctcctgaaa tggagttttg aagcaggatc actctatttg aaaatataca
    13201 tagaaaaact gtataatcct taaaataagc tgaaatctat tggaaacata cggtaaacaa
    13261 ttgaaaagat actatataaa gtggtacaat ggtagaaaaa taagctagta agaatcactc
    13321 ttattttagc gaaaaattac agaaatgaat ggtttttctt gatgaaacag agaaaagaat
    13381 tgtacctctt tcttggtcgg acagccttgt attttcttat ctttctaggg ctgctttact
    13441 tctttagcta tcttggtcag ggtcaaggaa gctttatcta taatgaattt taacttgaag
    13501 gagaatccct attgtgtcaa ataaaccaat agcagatatg attgaaacca ttgagcattt
    13561 tgctcagaca cagcctagct atcctgtcta taatgttttg gggcaggaac acacttatgg
    13621 cgatttaaag gctgattcgg atagtttggc tgcagtcatt gaccaactag gcttgcctga
    13681 gaagtctcct gtggttgttt ttggtggcca agaatatgaa atgttggcaa cctttgtagc
    13741 gctgactaag tcaggtcatg cctacattcc aattgatagc cattcggcct tggagcgagt
    13801 ttcagctatt ttagaagtag cagagccaag cttgattatt gccatttcag cctttccctt
    13861 ggagcaggtt tctacaccaa tgataaatct agctcaggtt caagaagcct ttgcccaagg
    13921 gaataactat gaaatcacgc atccagtcaa gggagatgat aattactaca ttatctttac
    13981 ttctggtacg actggtaagc ctaagggagt gcagatttca catgataatc tcctcagctt
    14041 tacaaactgg atgattacgg ataaggaatt tgcgacaccg agtcgtccgc aaatgctggc
    14101 acagccacct tattcttttg acttgtctgt catgtattgg gcaccgacct tggcacttgg
    14161 tggtacgctt ttcactcttc cttcagtcat cactcaggac tttaagcaac tctttgcggc
    14221 tatcttttca ttgccaatcg ctatctggac atcaacacca tcctttgcag atatggccat
    14281 gttgtctgaa tacttcaaca gtgagaaaat gcctggaatc actcatttct actttgatgg
    14341 tgaagaattg acggtcaaaa cagctcaaaa actgcgcgag cgtttcccaa atgcccatat
    14401 catcaatgct tacggcccaa cagaagcgac agtagctctg tcagcagttg ccgtgacaga
    14461 cgagatgtta gcgactctca aacgcctacc aatcggctat accaaggctg attctccaac
    14521 ctttatcatt gacgaggaag gaaataaact gccaaatggt gagcagggag aaatcattgt
    14581 ttctgggcca gctgtttcaa aaggttatat gaacaatcct gaaaaaacag cagaagcctt
    14641 ctttgagttt gaaaatctgc cagcctatca cacaggcgat gtgggaacca tgacagatga
    14701 gggcttgctt ctctacggcg gacgcatgga cttccagatt aagttcaacg gttaccgcat
    14761 tgagttagaa gatgtctctc aaaacctcaa caagtctcgc tttatcgaat ctgctgtcgc
    14821 agtaccgcgc tataacaagg accacaaggt acaaaatcta ttggcttatg tcatcttaaa
    14881 agacggtgtt cgtgagcagt ttgagcgaga tatcgatatt accaaggcca tcaaggaaga
    14941 cctgacagac atcatgatgt cctacatgat gccatctaaa ttcctttacc gagacagttt
    15001 gccactaact ccaaatggaa agattgacat caaaggattg attaacgagg tgaataagag
    15061 atgatggagt tttttcaaca gcttcctcat ttagagccat atggtaatcc tcagtatttt
    15121 gtttatgtga ttgctgcaac cttgcccatc tttataggcc tctttttcaa gaaacgcttt
    15181 gcctggtatg aagtgttggt aagtctcttc tttattgtca ccatgttggt gggtggaaag
    15241 accaatcaac tagctgcctt gggtatttac ctttgctggg aaatattgct cctgcttttc
    15301 tacaagcatt atcgaaaaag caaggatggc aagtgggtct tctacttagt tagttttctg
    15361 tccctacttc cgattatctt tgtcaaggtg caaccagcta tcaatggaac gcagtctttg
    15421 cttgggttct tgggaatttc ttacctgacc tttcgttcgg ttgggattat catcgagctg
    15481 agagatggag tgattaagga ttttaccctc tgggaattcc tccgtttcct tctcttcatg
    15541 ccaactttct cgagtggtcc aatcgatcgc tttaagcgat ttaatgaaaa ttatcagacc
    15601 attcctgagc gagatgagtt gatggatatg ctggatgaat ctgtccgcta tatcatgcgg
    15661 ggctttttgt ataagtttat cctagctcat gttttaggag agaccttact acctcctctg
    15721 aagaatttag ccttgcagtc aggtggcttc tttaatctct atgccttggc agttatgtat
    15781 acttttggtc tggagctctt ctttgacttt gcaggttatt ctatgtttgc tttggccatc
    15841 tcaaacttga tgggaatccg tagccctatc aactttaaca agcccttttt atcaagggat
    15901 ttaaaggagt tttggaatcg ctggcatatg agtctgtcct tctggttccg tgactttgtc
    15961 tttatgcgaa tggtgatggt gttaaccaga aagaaagtct ttaaaaatcg taatgtaacc
    16021 tcaagcatgg cctacattgt aaatatgctg attatgggat tttggcatgg cgtgacctgg
    16081 tactatatcg cctatggact ctttcatgga ctaggtttgg tcatcaatga tgcctgggtt
    16141 cgcaagaaaa aaacgctcaa taaggaacgg aaaaaagcag ggaaggctgc cctacctgag
    16201 aatcgctgga ttcagttgct tggcatggtt gtcactttcc atgttgtcat gttgtcattc
    16261 ttaatctttt ctggattctt gaataatcta tggtttaaaa aataaaagga aataaaatat
    16321 ggatatcaaa tcagaagtta tcgaaattat tgatgagttg tttatggaag atgtttctga
    16381 catgatggat gaagatcttt ttgatgcagg tgtcttggat agtatgggaa cggttgagtt
    16441 gattgtggag attgagaacc gttttgacat tcgtgtccct gtaacagagt ttggtcgtga
    16501 cgactggaat acagctaata aaattatagc tggtattgtg gagctacaaa atgcttaaac
    16561 gcttatggat gatcttcgga ccggtcttga tcgctggttt gttggttttt ctgctcattt
    16621 tcttttatcc tactgagatg catcataatc taggagctga aaagcgttca gcagtggcta
    16681 ctactatcga tagttttaag gagcgaagtc aaaaagtcag agcactatct gatccaaatg
    16741 tgcgttttgt tcccttcttt ggctctagtg aatggcttcg ttttgacggt gctcatcctg
    16801 cggtattagc tgagaaatac aatcgttcct accgtcctta tcttttagga caggggggag
    16861 ctgcatcgct taaccaatat tttggaatgc aacagatgtt acaacagctg gagaataaac
    16921 aagttgtgta tgttatctca cctcagtggt tcagtaaaaa tggctatgat ccagcagcct
    16981 tccagcagta ttttaatgga gaccagttga ctagttttct gaaacatcaa tctggggatc
    17041 aggctagtca atatgcagcg actcgcttac tgcaacagtt cccaaacgta gctatgaagg
    17101 acctggttca gaagttggca agtaaagaag aattgtcgac agcagacaat gaaatgattg
    17161 aattattggc tcgttttaat gaacgccagg cctccttttt tggtcagttt tcggttagag
    17221 gctatgttaa ctacgataag catgtagcta agtatttaaa aatcttgcca gaccagtttt
    17281 cttatcaagc aatagaagat gttgtcaaag cagatgctga aaaaaatact tccaataatg
    17341 agatgggaat ggaaaattat ttctataatg agcagatcaa gaaggatttg aagaaattaa
    17401 aggattctca gaaaagcttt acctatctca agtcgccaga gtataatgac ttgcagttgg
    17461 ttttaacaca gttttctaaa tctaaggtaa acccgatttt tatcattcca cctgttaata
    17521 aaaaatggat ggactatgct ggtctacgag aggatatgta ccaacaaacg gtgcagaaga
    17581 ttcgctacca gttagaaagt caaggtttta ccaatatagc agatttttct aaggacggcg
    17641 gggagccttt ctttatgaag gacaccattc accttggttg gttgggttgg ttggcttttg
    17701 acaaggcagt tgatcctttc ctatccaatc ccacaccagc tccgacttac catctgaatg
    17761 agcgcttttt cagcaaagat tgggcgactt atgatggaga tgtcaaagaa tttcaataga
    17821 taatataata tagaagagtt caagaatgaa actagttttc acgttttttc ttgactcttt
    17881 ttttgcttgt gatataatta actggtaaac aaaatgtcaa agaatagtat ttttctctta
    17941 aaaaagagaa gtctaaaagg aaaggagtca gatatgagac agctagcaaa ggatatcaat
    18001 gcttttttga atgaggtgat tttgcaggcg gaaaatcagc atgaaatcct aataggtcat
    18061 tgcactagcg aggtggccct gaccaatact caggagcata tccttatgct cttgtcagag
    18121 gaatctttaa caaattcaga attggctcgt cgtctcaatg tcagtcaggc ggcagttacc
    18181 aaggccatta agtctttggt caaggaaggg atgttggaaa catctaaaga ttctaaagat
    18241 gcgcgtgtga ttttttatca gttgactgac ttggctcgtc caatcgctga ggagcaccac
    18301 catcaccatg agcatacact tttaacctat gaacaagtgg cgactcagtt tactccaaat
    18361 gaacaaaaag tgattcagcg gtttttgact gctttagtag gagaaatcaa ataatgagat
    18421 atattacggt agaggatttg tccttctatt atgataagga gcctgttctt gaacatatca
    18481 attattgtgt tgatagtggg gaatttgtta ccttgactgg ggaaaatgga gcggctaaga
    18541 cgacgctcat caaggctagt cttggaattc tgcaaccacg cattggaaag gtggctattt
    18601 caaagacaaa tacgcaaggt aagaaattga gaatagccta tcttcctcaa caaattgcca
    18661 gttttaatgc tggttttcca agtacggtct atgaatttgt caagtcgggt cgctatccga
    18721 gaaaaggctg gttccgtcgt ttgaatgctc atgatgagga gcatatcaag gctagtctgg
    18781 actcagttgg catgtgggaa catcgagaca aacgcttggg gtctctatct gggggacaaa
    18841 agcagcgagc ggtaattgcg cgtatgtttg cttctgaccc tgatgtgttt atcctagacg
    18901 agccgacaac ggggatggat gcaggaagta aaaatgaatt ttacgaactc atgcaccaca
    18961 gcgcccatca tcatggcaag gctgttttga tgattaccca tgaccctgaa gaagttaagg
    19021 attatgcgga tcgcaatatt catctagtcc gtaaccaaga ctcgccatgg cgttgtttca
    19081 atgttcatga gaatggccag gaggtgggcc atgcttagtt tattatctta cgactttata
    19141 cagcgcgcct ttttggcggt tattgctatg agtcttttct caccggtatt gggaaccttc
    19201 ctcatcttgc gtcgtcagag tttgatgagt gataccctta gccacgtctc actttcaggt
    19261 gtagcctttg gtctggtttt ggggatttct ccaactgttt ctactattgc cattgtcttg
    19321 attgcggcgg tctttctgga gtatctccgt acggtttaca agagctttat ggaaatcggg
    19381 acagctatcc tcatgtcaac aggtctggct gtttctctga ttgtcatgag caagggtaaa
    19441 agctcgagtt caatgagttt ggaccaatat ctctttggtt cgatcgtgac tatcagtgaa
    19501 gaacaggtca tttccctctt tgtcattgcg gtggttgttt tgattttgac ctttctcttt
    19561 cttcgtccta tgtatatctt aacttttgac gaagatacgg cctttgtgga tggcttgcca
    19621 gttcgtacca tgtccattct ttttaacatg gtgacagggg tggctattgc ccttatgatt
    19681 cctgcagcag gagctcttct ggtatcgacc attatggtct tgccagctag tattgccctg
    19741 cgtctgggga aaaactttaa atcggttatg ctgcttgcca gtgcgattgg ctttttggga
    19801 atggtagcag gactttacat ttcctactat gcagaaacac ctgcaagtgc aagtattacc
    19861 attatttttg taactgtctt tatactaatc agtttagtaa gacgttttat caaataggag
    19921 acgaacgtga aaaaaattag cttattacta gccagtctat gtgccttgtt tttagtggct
    19981 tgttccaatc aaaaacaggc agatggtaaa ctcaatatcg tgacaacctt ttaccctgtc
    20041 tatgaattta ccaagcaagt cgcaggagat acggctaatg tagaactcct aatcggtgct
    20101 gggacagaac ctcatgaata cgaaccatct gccaaggcag ttgccaaaat ccaagatgca
    20161 gataccttcg tttatgaaaa tgaaaacatg gaaacatggg tacctaaatt gctagatacc
    20221 ttggataaga aaaaagtgaa aaccatcaag gcgacaggcg atatgttgct cttgccaggt
    20281 ggcgaggaag aagagggaga ccatgaccat ggagaagaag gtcatcacca tgagtttgac
    20341 ccccatgttt ggttatcacc agttcgtgcc attaaactag tagagcacat ccgcgacagc
    20401 ttgtcagcag attatcctga taaaaaagag acctttgaga agaatgcagc tgcctatatc
    20461 gaaaaattgc aagccttgga taaggcttac acagaaggct tgtctcaagc aaaacaaaag
    20521 agctttgtga ctcaacacgc agcctttaac tatcttgcct tggactatgg actcaaacaa
    20581 gtcgcaatct caggcctttc tccagatgca gagccatcag ctgctcgctt ggcagaattg
    20641 acagagtatg tcaagaaaaa taaaatcgcc tatatctatt ttgaagaaaa tgcctcacaa
    20701 gcccttgcta acacactttc aaaagaagca ggtgtcaaaa ctgatgtcct caatccttta
    20761 gaaagtctga cagaagagga caccaaggct ggagaaaact acatttccgt gatggagaaa
    20821 aacctcaagg ctttgaaaca aacaacagac caagaaggcc cagcaatcga acctgaaaag
    20881 gcagaggata ccaagacagt ccaaaatggt tacttcgagg atgcagctgt caaggaccgc
    20941 accttgagtg actatgcagg taactggcaa tcagtttatc ctttccttga agacggcacg
    21001 tttgaccaag tctttgacta caaggctaag ttgactggta agatgaccca ggctgagtac
    21061 aaggcttact atacaaaagg ctatcagaca gatgtgacta agattaacat tactgataat
    21121 actatggaat ttgttcaagg tggacaaagc aagaaataca cttacaagta tgtcggtaag
    21181 aaaattttga cttacaagaa aggcaatcgt ggcgtgcgtt tcctctttga agccacagat
    21241 gctgacgctg gacaattcaa atatgttcag tttagtgacc acaatgttgc cccagttaag
    21301 gcagaacatt tccatatctt ttttggaggt acaagccaag aagctctatt tgaagaaatg
    21361 gataattggc caacctacta cccagataac ctatctggcc aagaaatcgc ccaagaaatg
    21421 ttggcgcatt gatgagaaat cgactagttc ataagagcta gtcggttttt tgatactaga
    21481 tggctaactt cattatagac ctttcagaac taagggaacc tgaaaaaata aataaaactc
    21541 ttgaaatatc tggacttata tgctagaatg tagttagtgt ataaggttca ttagaacacc
    21601 aaagccccta actagtgcca tagttaaggg cttttttgac gtatcttagc gatttaatgg
    21661 gtgtttatag gctagtcagt cggtctactt cttaccatct agccatttgc agacgaaata
    21721 caagataatt ccagctataa catctgctat aatagtaaga gcaagctctg gtataaggct
    21781 cattagtttc acctcctctc acgaacccat aggaacgtaa tcggtaaccg atgacaaaag
    21841 tattatatca cactaaattt agatcatcaa cctcacttaa tgcttgaact attgtagatt
    21901 atatgctaaa atgtagttaa ttgataaggt tcattagaac accaaagccc ctaactatgg
    21961 ccgtagttaa gggctttttt gacgtatctt agcgatttaa cgggtgttta taggctagtc
    22021 actcggtcta cttcttacta tctagccatc tgcagacgaa atacaagata attccagcta
    22081 taacatccgc tataatagta agagcgagct ctatgataag gctcattagt ttcacctcct
    22141 ctcacgaacc cataggaacg taatcggtaa ccgatgacaa aaatagtata ccacaataca
    22201 tttagatcat caaggtcact taattcttga aatatagggt ttaggcgaca aagtctttaa
    22261 aatcagaaaa acgcataata tcaggtgtgc aaaaacttga tactatgcgt tttattgtgg
    22321 gaaggtttac tccattttct cctgaaattg agtttttgtc cagcctctgt ttttagggtt
    22381 gctgagaaaa taatgtcatg tggtgaatat ttgtaaatca gtcagcagac agaacgaata
    22441 ctcttcgaaa atctcttcac atcatgtcag cttcgtcttt ccgtatatat gtgactgact
    22501 tcatcagttc tatctacaac ctcaaaacag tgtttcgagc tgactttatc agttttcaaa
    22561 tctgtacttt gagcaagctg agactagctt cctatttgat tttcattgaa tatcagaaac
    22621 ccattctcca tcaaataatt cgactgcgtc taataatttt tgatctggca cggtgtctga
    22681 aataaaggtt gtgtatttgg agaggggatt aattttaaaa aatccagtct tgtaaaattt
    22741 agaactatca atcagtaaga tggtttcatg ggctttgtca ataatattct tttttgaaat
    22801 agcttggctg agagaagctt cataaacata ttggtcatca atacctcttg ctgaacaaaa
    22861 tgctaaatcg atattaaaat gatctaataa agaattttcc ttatcatagt tgaccacgga
    22921 acaggattga tgtttgacct cgccagatgt gataaagatt ttggagctat ctttaacagt
    22981 ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa ataatcaaat tatcaagttc
    23041 agaaagatag ggacaaagtt cgtagacagt agtactggaa tccagataaa cacacatacc
    23101 agaccgaata aagtctttag cgagactagc gattagtctt ttttgcctag tactttctcc
    23161 ttcccgtatt tgatgagaaa gttcaattgt gttcatagag gacagggtca cgtatccgtg
    23221 ctttcttttg ataagacctt gattttctaa gaaaattaaa tcacgacgta aggtacttgt
    23281 gctggagaaa gtgatttctg ccagctcttt tacggcaatt ctttttttct ttttaataat
    23341 ttcaatcaat tcaagtacac gttcatcttt tatcataagc tcctcctaat ttatcatttc
    23401 aactatatta tagcacaaat tggaggaatt tgaattattt ttatgaatat tgggttaaca
    23461 tttgaacatt attcaagtaa gcgttcacat attgaaaaaa taaaatgtgg ggattataat
    23521 aaagttaatc aaggacgaag agagaagaaa aatggaagcg gttttagcaa tagatttagg
    23581 tgcgacttct ggaagagcaa tcgttggtta cctttctgaa aataaactag taatggaaga
    23641 aataaatcgc ttttctaatc tacctattag agtaaaaggg catttatctt gggatattga
    23701 ctttctacta gctaaaattc ttgaaagtat ccgcttggct aatactagtt acaagatttt
    23761 atctatcggt attgacacat ggggagttga ttttggactg attgataatg aaggtaagct
    23821 gttatcacaa cctgttcatt atcgtgatga aagaacaaag ggagtgttaa aggaaatatc
    23881 tgaaatgact gaattagaaa aactgtattc agagacagga aatcagatta tggagataaa
    23941 taccttgttt caactcttta aggcacgtca agaatctcct gactctttct ataagaccaa
    24001 taagattctt ttaatgccag atttgtttaa ttatctcttg acaggtaagt ttgctacaga
    24061 aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg agtcaaaatt ggaatcagaa
    24121 tatcttaaaa ctatttgaat tggattcatc tttacttcct gaaattgttt cagagggaaa
    24181 tgttcttgga aggataaaaa aggagtatgg tttaggcgat attcctgttg tgaatgtttg
    24241 tagtcatgat acagcaagtg cgattgtctc agtacctaag acagaaggta gtttatttat
    24301 ttcatcaggt acttggtctt tggttggagt ggaacttact tcaccgattc ttactaccga
    24361 atccttcagt tatggattta caaatgaagt cggtaaagat ggagagatta catttctgaa
    24421 gaattgtaca gggttgtgga tcatagagga actaagacgt tcatttgaac gaagagggaa
    24481 agcctattct tttgatgata ttaggacaat ggtggagaaa gaaaaagaaa atcttcctct
    24541 gattgatact gaatcaactg aatttgcaac agaatctgat atgcacaaga ctttgacaga
    24601 atatctagct tatcatcatg aaactagaga gtggacagat ggacaactat ttaagattgt
    24661 ttatgaaagc ctagctgaaa cgtataggaa agcgatagag ttactagaag aactaactca
    24721 taaggtttat aagaggatat atgtgattgg aggaggtgct agagccagtt actttaacca
    24781 aatgattgct gatagaactg gtaaagaggt tcttacaggt tcgactgagg gtacagctgt
    24841 ggggaatatt gttgtgcagc tcatagctat gggacaatta aaagggatgg aagaagctca
    24901 ccatgttatt gaggagtttc tacaattaga gagttattac tcccaaaaga attaaaaaga
    24961 ttgagagttt gtaaatttgc ctccctcccc cttcttaagt tttgtacaag aaggggggat
    25021 aattggtgaa ttgaaaaata tttagtgttt tgatatgagg aggacaagaa tgtcagatgt
    25081 aaaacaagaa ttaattaagt atggcaagaa gctagtagaa acagatttga cgaaaggaac
    25141 aggtgggaat ctcagtgttt tcgatcgtga aaaacaattg atggcaatta ccccgtcggg
    25201 tattgatttc tttgaaatca aagaatccga tattgtagtg atggatatta atggaaatgt
    25261 tgtagaggga gaacgcttgc catctagcga atggtatatg catttgattc aatatcaaac
    25321 tcgtgatgat atcgatgcaa ttatccatgc tcatacaact tatgcaacag tattagcttg
    25381 tctcagagaa ccacttccgg ctagtcatta tatgattgca gtggcaggga aagatgttcg
    25441 ggtagctgag tatgcaacat atggtacgaa agaattggct gtgaatgcag ctaaagcaat
    25501 ggaaggtcgt agagcagttt tactagcgaa tcatggaatt ttagcaggtg cacaaaattt
    25561 attgaatgca tttaatattg ttgaagaagt tgaatattgt gcaaaaattt attgtttagc
    25621 taagaatttt ggagagccag tagttcttcc tgatgaggag atggatttaa tggcagaaaa
    25681 atttaaaaca tacggtcaga gaaaataggg aggatattaa tgttaaaaca tataccgaaa
    25741 aatatttctc cagatttatt gaagacttta atggaaatgg gacatggaga tgaaatagta
    25801 ttagctgacg cgaattatcc ttctgcctca tgtgcaaata agctaattcg ttgtgatggc
    25861 gtaaatattc cagaattatt agattccatt ctgtatttaa tgccattaga tagttacgtc
    25921 gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg atattcctaa gatatggggt
    25981 acctatagac agatgattga aggtcatggt acagatctta aaacgattac ttatcttaga
    26041 agagaagact tttatgaacg tagtaagaaa gcttatgcta ttgttgctac aggagaaact
    26101 tcactttatg ctaatattat ccttaagaaa ggagtagttg ttgaaagaga aaatgtttaa
    26161 tagaggaatt ttagttgcca gtcatggtaa ttttgctagc ggagctctca tgaccgcaga
    26221 aatgtttgtt ggtgagacaa caaatgatag agttaggaca ttaggtttga tgcctggaga
    26281 gaatattgta gagtttgaac attattttaa aaatcaagta aatgaactgt tagactcaaa
    26341 tcaagaggtt atcgttttga ctgacttgat tggaggaagt cctaataatg tggctttgtc
    26401 acggttttta aatttggatt cagttgatat tgtaacaggg tttaatatcc ctctcctagt
    26461 ggaattaata tcaagttatg attcaaaaat caatttagaa gaaattgttc aaaatgctca
    26521 aaatagtttg tttaatgtta aacaacaact taacgtagag gaggaagagg atttatgtct
    26581 atagagtttg ttcgtattga tgaccgtctg gtacatggtc aagttgtcac tacgtggcta
    26641 aaaaagtatg atattgagca agttatcatt gttaatgatc gcatctcaga agataaaaca
    26701 cgacaatcta ttttaaagat ttctgcaccg gtaggtttaa aaattgtttt ctttagtgta
    26761 aaacggtttg tggaagtttt aaactctgtg ccaataaaaa agagaacaat gctgatatat
    26821 acaaatccaa aagatgtgta tgattctatt gaaggaaatt taaaattgga gtacctcaat
    26881 gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa cgggaggtgt agctctaggt
    26941 gaagaagaca aatattattt taagaaaata gttgataagg gaacgagagt tgaaattcaa
    27001 atggttccta atgataaagt tacaatgttg gaaaaatttt tataaaaata atttaaggag
    27061 gtacagtata tgctattcac acaagcatta ctggtgacat tagttgggat tattgccact
    27121 attgactata atggaccgtt atttatgatt caccgtccgt tagttacaag tgcaatggtt
    27181 ggcttagtct taggagattt cacccaaggt gttcttattg gttcagctct tgaattaact
    27241 tggctcggtg taacaggtat tggaggttac actccaccag atactatttc aggtgcgatt
    27301 attggtactg catttggtat tttgtctggt caaggagaaa ctgctggtat cgctatagca
    27361 gttccaattg cagttgctac tcaacagttg gatgttcttg caaaaacttt agatgtttat
    27421 tttgtgaaaa aagctgataa tgatgctaaa aacggagatt attcaaagat cggtttttat
    27481 cattattcaa gtttggtttt aatcacttta tttaaaattg taccaatttt cctagctatt
    27541 atgcttggag gggaatatgt ggcagacttg tttgctaagg ttccaccaat cgttatgcag
    27601 ggacttaact ctgcaggtgc tttactacct tcaattggtt ttggtatgct tttaaatatg
    27661 atgctcaaga aaaatatgtg ggtattcttg ttgattggat tcatttgttc tgtgtatgga
    27721 ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg tagcatactt ctacgatatg
    27781 attggaagta aaccacaaga aacaacttca agtagtgatg ttgaggagga tcttgatcta
    27841 tgatgaataa taaagtaact aaagttgaac ttaaaaaagt tttcaaacga agttttatgt
    27901 atggttcttc atggaactat gagagaatgc agaacctagg ttttctatat acaattcttc
    27961 cagtattgaa aaaactatac ccagacaaag attcagcttc tcctgcaatg aaacgtcacc
    28021 ttgagttttt caatactcat caaacagcgg caccatttat tcttggagtt acttccgcta
    28081 tggaagaaca agaaggaaat gaaggtgcag cttcaattac tggtattaaa gttggcttga
    28141 tggggccact ggctggtcta ggagatagtt tgttctggct gacactagtt cctatctgtt
    28201 ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt aggtatcttt atcgccttaa
    28261 tattgtttaa tattattaat attcctgtta aatatttcgg tttgaaatat gggtatacta
    28321 agggttctag tcttatccaa gaaaataata caaaaggaac attgaatcgc gttacgagta
    28381 tggcgacagc attagggcta gtactagtgg gtggtttgat tccatcaatg gttggtatta
    28441 attttggatt agaatttaag cagggggaac ttgttatttc tgttcaagaa atgattacaa
    28501 aattaattcc aggatttatc cctatggctt tgactttatt aatgtgtaaa ttaattagaa
    28561 aaggaaagaa tccggttgta ctaatcttta gtgttatggc tattggagtt atcctagttg
    28621 ttttaggaat tttgaagtag tagaaagtgt ggaggtggta tttgggatat cacctccatt
    28681 ttggaagaga ggtaaagagt gaaattatgg tataagaaag ctgccgcaaa ttggaatgaa
    28741 gccttgccga ttgggaacgg tcatttaggt ggtatgattt atggttcagc tacaaaagaa
    28801 tgtattcaac taaacgatga gactatttgg tatagaggaa agtcagatag aaataatcca
    28861 gactcactat tgcatcttaa aaaaattcgg gaatatcttt tagatggaga aattcagaaa
    28921 gccgaagaat tgataaagtt aacaatgttt gctaccccaa gagatcaaag ccactatgaa
    28981 ttacttgggg aactttgcat tgagcatata gatattcagt cttgtgctct ttcattgtat
    29041 gaaagagagc tagatttaga tacagctatt tctaatgttg tgtttgagcc taatagttgt
    29101 aatttacaaa taaaaagaga atattttacg agttttaata agaatatttt atgttgccgt
    29161 atagtgtcat cagttcaaaa cacattaaat ttaaacatta atttgggtag aaataaacgg
    29221 tttaatgacg aagtatctaa actggattca agtacaattt taatgtcggc ctctgctgga
    29281 ggtagaaaag gtgttcagtt taaagtagta tgtcattcta aggttacgga tggtgaagta
    29341 agtgtattgg gagagacaat agttattcgg aatgctacag aggtatttct ttatctcaaa
    29401 tcaatgacgg attattgggg aaatatagat atttcttctc ttcagggaga atttagtagt
    29461 attgattact ttacagaaaa agatgaacat gtaaaaaaat atcaggagca atttaataga
    29521 gttgatttta aactagacta tagtaaaggt tgtcttagca ttccaacgaa tctacttctt
    29581 gaaaacacta aaaagtatag taactacttg actaacttgt tatttcatta tggaagatat
    29641 ctgttaatat cgtctagtca accgaatggt ttacctgcca atcttcaagg aatatggtgt
    29701 gatgaattaa atccaatttg gggttctaaa tatacgatta atattaatac tcaaatgaat
    29761 tattggatgg taggtccatg tgatttacca gaagtagaat atccattatt tgatatgctc
    29821 gaaagaatga gagaaccggg aagactaacc gctaagaaaa tgtatggagc tagaggtttt
    29881 acagcacatc ataatacgga tggttttggc gatacggctc cccaatctca tgccatgggg
    29941 gctgcaattt gggtattaac tattccatgg ttatgtactc atatttggga acactattta
    30001 tatttccaag atgagcgtat tcttacggaa cattttgaaa tgataaaaga agcatttctt
    30061 ttctttgaag attatttatt tgaggtggat ggctacttga tgacaggtcc aagtgtctca
    30121 ccggaaaata aatatcgctt aaaaaatggt attgaaggaa atgcttgtct atcatctaca
    30181 attgataatc aaattctaag atatttttgt gattcatgca ttggcattgc aaaacaatta
    30241 ggagacaatt cggattttat tagtcgtgtg aaggagttaa aaaagaaatt acctagaaca
    30301 aaaataggta gtaatgggca aatacaagaa tggctagagg attatgaaga agtagagcct
    30361 ggtcatagac acatttcacc tctatttggg ctttatcctt ataatgagat tgatattcat
    30421 aaaactccgg aattagcaga agcagctaaa atcactatca ataggagatt atcaaacgct
    30481 aactttttat cttcacagga tagggagcaa gcgattaata attggttagt aagtggtttg
    30541 catgctagta cacaaacagg ttggagtgct gcatggctga ttcatttttt tgcgagacta
    30601 tatcaaggtg aacctgctta taaccagatt aatggtttgt taaataatgc gactcttggc
    30661 aatttatttc ttgaccatcc accatttcaa attgatggta atttaggttt ggtgagtgga
    30721 atttgtgaat tattagtaca gagccatcat aattggttat cactaattcc agctttacct
    30781 tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa gaggaggata taaggtatcg
    30841 tttgcttgga aaaatgggga tataacattc ctaaaattgg aaggaggaaa caaagatcaa
    30901 aaagtaagag taagaatata tggcaaaaat actgatgtac aaaatattga attggtattt
    30961 aattcagaaa aaattattga gttaaatttt taggtataag tcatgaataa agaaaaaata
    31021 aaaagaaaat taatcacaat attgtttgta tgtattggga tgttatgttt tggattgtta
    31081 gcaggagtta aggctgataa tcgtgttcaa atgagaacga cgattaataa tgaatcgcca
    31141 ttgttgcttt ctccgttgta tggcaatgat aatggtaacg gattatggtg ggggaacaca
    31201 ttgaagggag catgggaagc tattcctgaa gatgtaaagc catatgcagc gattgaactt
    31261 catcctgcaa aagtctgtaa accaacaagt tgtattccac gagatacgaa agaattgaga
    31321 gaatggtatg tcaagatgtt ggaggaagct caaagtctaa acattccagt tttcttggtt
    31381 attatgtcgg ctggagagcg taatacagtt cctccagagt ggttagatga acaattccaa
    31441 aagtatagtg tgttaaaagg tgttttaaat attgagaatt attggattta caataaccag
    31501 ttagctccgc atagtgctaa atatttggaa gtttgtgcca aatatggagc gcattttatc
    31561 tggcatgatc atgaaaaatg gttctgggaa actattatga atgatccgac attctttgaa
    31621 gcgagtcaaa aatatcataa aaatttggtg ttggcaacta aaaatacgcc aataagagat
    31681 gatgcgggta cagattctat cgttagtgga ttttggttga gtggcttatg tgataactgg
    31741 ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt atacaaacac atttgaaact
    31801 ggaagagcta gggatatgag atcctatgca tcggaaccag aatcaatgat tgctatggaa
    31861 atgatgaatg tatatactgg gggaggcaca gtttataatt ttgaatgtgc cgcgtataca
    31921 tttatgacaa atgatgtacc aactccagca tttactaaag gtattattcc tttctttaga
    31981 catgctatac aaaatccagc tccaagtaag gaagaagttg taaatagaac aaaagctgta
    32041 ttttggaatg gagaaggtag gattagttca ttaaacggat tttatcaagg actttattcg
    32101 aatgatgaaa caatgccttt atataataat gggagatatc atattcttcc tgtaatacat
    32161 gagaaaattg ataaggaaaa gatttcatct atattcccta atgcaaaaat tttgactaaa
    32221 aatagtgagg aattgtctag taaagtcaac tatttaaact cgctttatcc aaaactttat
    32281 gaaggagatg ggtatgctca gcgtgtaggt aattcctggt atatttataa tagtaatgct
    32341 aatatcaata aaaatcagca agtaatgttg cctatgtata ctaataatac aaagtcgtta
    32401 tcgttagatt tgacgccaca tacttacgct gttgttaaag aaaatccaaa taatttacat
    32461 attttattga acaattacag gacagataag acagctatgt gggcattatc aggaaatttt
    32521 gatgcatcaa aaagttggaa gaaagaagaa ttagagttag cgaactggat aagcaaaaat
    32581 tattccatca atcctgtaga taatgacttt aggacaacaa cacttacatt aaaagggcat
    32641 actggtcata aacctcagat aaatataagt ggcgataaaa atcattatac ttatacagaa
    32701 aattgggatg agaataccca tgtttatacc attacggtta atcataatgg aatggtagag
    32761 atgtctataa atactgaagg gacaggccca gtcccttttc caacaccaga taaatttaat
    32821 gatggtaatt tgaatatagc atatgcaaaa ccaacaacac aaagttctgt agattacaat
    32881 ggagacccta atagagctgt ggatggtaac agaaatggta attttaactc tggttcggta
    32941 acacacacta gggcagataa tccctcttgg tgggaagtcg atttgaaaaa aatggataaa
    33001 gttgggcttg ttaaaattta taatcgcaca gatgctgaga ctcaacgtct atctaatttt
    33061 gatgtgattc tatatgacaa taatagaaac gaagttgcta agaaacatgt taataatttg
    33121 tcgggtgaat ctgttagtct agatttcaaa gaaaaaggag caaggtatat taaagttaaa
    33181 ttactaacga gtggagtgcc tttgagttta gcagaagtag aggtttttag agaatcagat
    33241 ggtaagcaat ctgaagagga tatagataaa ataacagaag ataaagtagt ctctacaaat
    33301 aaggtagcta ctcaaagttc aaccaattat gagggtgtag ctgctttagc agttgatggt
    33361 aataaagatg gagattacgg acatcattcg gtgactcata ctaaggcaga ttctaacgct
    33421 tggtggcagg tcgatctggg agaagagttt acggtttcta aagttgatat ttataataga
    33481 acagatgccg aacctcagcg tttatctaat tttgatgtta tttttctatc ttcatcagga
    33541 gaagaagttt ttagaagaca ttttgataaa gtagttgatg gtttgttatc tttaaaagta
    33601 ccttctgtag gggctaagct agtcaaaata gaattaaaat cagcagctat tccgttaagt
    33661 ttagcggaag ttgaagtcta tggttcaaag agaactccga agaaactttc taatattgca
    33721 ttaaccaaag aaactcgaca gagttcaacg gattacaatg gtttttctcg tctagcagtt
    33781 gatggaaata aaaacggaga ttatggtcat cattcagtga ctcataccaa aggagattct
    33841 ccttcatggt gggagataga tttagcacaa accgaagaat tagaaaagtt aattatttat
    33901 aatagaacag atgctgaaat tcagagatta tcaaattttg atattattat atatgattca
    33961 aataatcatg aagtttttaa acaacatatt gacagtttag aaagcaataa tctatccata
    34021 gacttaaaag ggctgaaggg aaaaaaggtt agaatttctt tgagaaacgc aggaattcct
    34081 ttaagtttgg cagaggtaga ggtttatact tataagtaat tttaaaaatt atcatcggta
    34141 gtatgaaaga aacagaaaaa taagaggaaa atagtatgat tcaacatcca cgtattggta
    34201 ttcgtccgac tattgatggt cgtcgtcaag gtgtacgcga atcacttgaa gtacaaacaa
    34261 tgaacatggc taaaagtgtg gcagatttga tttcaagcac attgaaatat ccagatgggg
    34321 aacctgtgga atgtgtgatt tctccatcta ccattggtcg tgttccagag gctgcagctt
    34381 cccatgagtt gtttaaaaaa tcaaatgttt gcgcaacaat tacagttaca ccatgctggt
    34441 gttatggtag tgaaactatg gatatgtctc cagatattcc tcatgctatt tggggattta
    34501 atgggacaga acgcccagga gctgtctatc ttgcagctgt actagcttca catgctcaaa
    34561 aagggattcc agcctttggg atttatggta gagatgttca ggaagctaat gatacagata
    34621 ttccagaaga tgtcaaagaa aaacttttac gttatgcgcg tgcagctctt gcaactggct
    34681 tgatgagaga cactgcttac ctatcaatgg gtagtgtttc gatggggatt ggtggttcta
    34741 ttgtaaatcc ggatttcttc caagaatact taggaatgcg aaatgaatcg gtagatatga
    34801 cggagttcac acgccgtatg gaccgtggta tttacgaccc tgaagagttt gaacgtgcta
    34861 tggtttgggt aaaagaacat atcaaagaag gagttgaccg aaatcgtgag gatttgattc
    34921 tttctaaaga agagaaagaa aaacaatggg aatttgttat taagatgttc atgattggac
    34981 gtgacttaat ggttggtaac ccaagacttg ctgaacttgg ttttgaggaa gaagcagttg
    35041 gtcaccatgc tttagtagct ggtttccaag gtcaacgtca gtggacagac cattttccaa
    35101 atggagattt tatggaaact ttcctcaata ctcagtttga ctggaatggt attcgaaaac
    35161 catttgtatt tgcgacagag aatgattcac taaatggtgt gtctatgctc tttaattatc
    35221 tactaacaaa tactccacaa atctttgctg atgtgcgtac ttattggagt ccagaggctg
    35281 ttgaacgtgt aacaggatat actttagagg gtcgtgctgc agctggcttc ttacatctaa
    35341 tcaactctgg ttcttgtaca ttggatggta caggtcaagc tactcgagat ggcaaacctg
    35401 ttatgaaacc attctgggag ttggatgaaa gtgaagtaca ggctatgctt gaaaatacag
    35461 acttcccacc agcaaaccgc gagtacttcc gtggaggagg attctcaact cgtttcttga
    35521 cgaaggggga tatgccagta acaatggtac gtctcaatct tctaaaaggg gttggtccag
    35581 tgctacaaat tgcagaaggt tacacacttg aacttcctga agatgttcac catactttag
    35641 ataatcgtac agattcagga tggccaacta cttggtttgc tccacgtttg acaggaaaag
    35701 gtgctttcaa gtctgtctat gacgtcatga ataattgggg agctaatcac ggagccataa
    35761 catatggaca cattggagca gacttgatta ccttggcttc tatgttgaga attcctgtca
    35821 atatgcataa tgtacctgag gaagatatct ttagacctaa aaattggtcc ttatttggaa
    35881 cagaagatct agaatcagca gactatcgtg catgtcagtt gttgggacca ctacataaat
    35941 aaaacttgtt tatataggag gtgaacttac gtccctccta tccttttaaa aagatttgtt
    36001 aaacaattca caaataattg aaaacgaata caaaaagtaa tataatgatg ttaaatagat
    36061 agcgcggagg cgcaggagga aaattatatg gctatatttt atgttccggc agtcaacctt
    36121 attggaaaag gtgttgtaaa tgaagtgggt ccttatatca aggaacttgg ctataaaaag
    36181 gcacttttgg tgacagataa gtacatcgaa ggcagtgata ttttacctaa gactttaaaa
    36241 ccactggata cagaaggaat cgaatatgtc atctttagcg atgtagagcc aaaccctact
    36301 tgtaaaaatg tcacagatgg ggtagctgct ttgcaagaac atggctgtga ctttatcatc
    36361 agtcttggcg ggggttctcc acaggatgca gctagttgta tttctatcat ggctacaaat
    36421 ggtggaaaac cacaggatta tgaagggctt cataagtctg ctaaaaaagg tttgccagtt
    36481 gtggctatca atacaacggc aggtacatca gcagaaatta ccattaacta tgtgattact
    36541 gatgaagaac gcaaggttaa gatggtaatg gttgacaaga atagccttgc cttgatttct
    36601 gtcaatgacc ctgaactcat gctttccaaa cctaaaggcc tgactgctgc tactggtatg
    36661 gatgctctga ctcatgctgt tgaagctttg gtaacacctg gtgcttatga tgtaaccaag
    36721 aaactgtcta ttggtgctat tgagcttatc aaggaatatc ttcctcgtgc tgtagaaaat
    36781 ggacatgata ttgaagcgcg tgaaggtatg gtcaatgcca tcttccttgg tggtatgagc
    36841 tttaataatg ctggtcttgg ctatgttcac tcaatggctc accaactcgg tgcagtatat
    36901 aatttgccac atggcgtgtg ctgtgccatg ttgctaccag ttatagaacg tgaaaatgct
    36961 aaacgtgtac cagaagcttt ccgcaatgtt gccaaagcct tgggacttca tgtagaaggt
    37021 aaatcagatc aagaatgtgc cgattatgcg attgctgaga ttgagaagct ttctgagaca
    37081 gtaggtattc ctaagaaact gactgaactt ggtattgaag aaaaagattt cgactttgaa
    37141 tacctttcta agaatgcctt gattgatgcc tgcgcaccag gaaatccatt tatgccaacc
    37201 ttagaagaaa cgattgcctt ttataaagag ttattttagc aagagattgg acgacaatag
    37261 gacaattcac ctctaattat tgacatttca ggaaaaatcg cagtaaaaac ggcacagcct
    37321 tctttaaatg tgctataata ctagaaaaat acttgtggag gttccattat ggcaatattt
    37381 ttcatgattt ttctgattgt ttgtgtgctc ctattggtga tagtcacact gagtacagtt
    37441 tatgtggttc gtcagcagtc ggtggcgatt attgaacgct ttgggaaata ccaaaaggtt
    37501 gctaatagcg gtattcatat tcgcttgcct tttgggattg actcgattgc agcacggatt
    37561 cagttgcgct tgttgcaaag tgatattgtg gttgagacta agaccaagga caatgtgttc
    37621 gttatgatga atgtagcgac tcagtaccgt gtcaacgagc agagcgtgac agatgcttac
    37681 tataaactca tacgtccaga atctcagatt aaatcttata tcgaagatgc tcttcgctct
    37741 tctgttccaa aattaacctt ggatgaattg tttgagaaaa aagatgagat tgcccttgag
    37801 gttcaacacc aagtagcaga agaaatgacc acttacggct acattatcgt gaaaaccttg
    37861 attaccaagg tcgaaccaga tgcagaagtt aagcaatcta tgaatgaaat caatgcggcg
    37921 caacgtaagc gggtcgcagc acaagaattg gcggaagctg acaagattaa aattgtcact
    37981 gcagctgaag ccgaagcaga aaaagaccgc cttcatggtg tggggattgc ccaacaacgt
    38041 aaggcgattg tggatggatt ggcagagtct atcaccgaac tcaaggaagc caatgttggc
    38101 atgacagaag aacaaatcat gtctatcctc ttgaccaacc agtatttgga taccttgaat
    38161 acctttgcct ctaaaggaaa tcaaaccatc tttttaccaa atactccaaa tggtgtggat
    38221 gatatccgta cacaaatctt gtcagccctt cgcgctgaga agaaataata gactaatact
    38281 cttcgaaaat ctcttcaaac tacgtcagcg tcgtcttgcc gtatagatgt tactgacttc
    38341 gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag tcttatctac
    38401 tacctcaaaa cggtgttttg agcaacctgt agctagtttc ctagtttgct ctttgatttt
    38461 cattgagtat aaagagcttg gcaacaggct ctttttgtat tgcgtttatt aagaaaaaca
    38521 aaaaacatcg atatacattt aactaaaaat tattgtatgt tatctccctt aattaggaat
    38581 gataagggaa taactagaaa gatttgtgaa tacaaactat ttctgatata caaaatatac
    38641 agtaataatg aatgatggga gatgggatga aagaatttca atttgagaga aagcagcgtt
    38701 tttctttgag gaaatatgca ataggagctt gttcggtctt gctaggaacg agtttatttt
    38761 ttgctggtat gggtgctcag cctgtacagg atacagaaac gagttcagca ctaatttcaa
    38821 gtcattattt ggatgagcag gatttatctg aaaagctgaa atctgagttg caatggtttg
    38881 aattagaaaa caagcttttg aacttatggg agcattaggt tactatgaag gatttgttcc
    38941 ttatgtttca aatcaatacc aaaaccaagc tgaagaagaa tacaaaccgc tatctgataa
    39001 atatattttc gaaaaaatct taggaaaaac atatgcagcc ttcaaaaaag atcaaattaa
    39061 tgagcgtgtc gagaaattag gtaagttaaa acctattaca ataaattaca acggaaaatc
    39121 agaagtaatt gatagtaaag aaaaattaca agagcttatg aataaagccg ttaaagacga
    39181 agtggctcaa atatagtaaa atgaaataag aacaggacaa atcgatcagg acagtcaaat
    39241 cgatttctaa aaatgtttta gaagtagagg tgtactattc tagtttcaat atactataaa
    39301 atcaggcaat accacggcta aaaagtttga gtttatcgaa ataccagtgc aaaaactgaa
    39361 aaaagcaatt tataaagctc atctcaaaga ttcagatgac tttagaccag aaacatccac
    39421 accaaatctt tttgaaagct gtttgaagct ttgtccttgc tttcttagtt catagatctg
    39481 aactttatct tcataactca atttcataat aaaacacccc aaaagttaga tttattctgt
    39541 ctaacttttg gggtgcagtt cattaatcgg tcgatttttt ttgtagaaac agttgcctga
    39601 ttaagttgca agtcgataga cggcttcggc ataaatatcc atagcacggt acaaatcttc
    39661 tagaacggca cattcatttg cctgatgttc tgtctgcttc gctcctggga ataaggcgcc
    39721 gaaggctaca caatttggca tggtgcgagc aaaagtggca ccaccggatg aaatagcagg
    39781 actgttatcg ccagtctttt cttggtagat ttgcatcagt gtgctaacga gtttactgtc
    39841 ttttgcgacg tatagaggcg ctagatagtc aaactcttcg tagcggagtt ggtagttttg
    39901 tgcacatctt gtaagcaact ctactagttc ttccttgtca gctaagacag gagtccgaat
    39961 gtcaatacgg atttcagaac gttcatgatt gatcatgaga cctgcgacat taaaggatag
    40021 gtgaccagaa ggttcatctg ctatatcacc aaagatttgt cttcctgtgc cgtcttgacc
    40081 tgcttgtgtt gcaagaaaac tgagagcagg gtgttcttgg agaggagcaa gaatggtagc
    40141 tagtcggatg acagcattga taccttgact agcatcctta gcatgctttg gcactccgag
    40201 aaccgttacg gtttgttcag tggtttggta atcataacca gcttctttga gaccgttaca
    40261 aacctgttca tagaggagac cttggtagtt ggccttgtct ggtacaacgt taaaggcgcc
    40321 tcctacttca agctctagtt gatccgatcc cgggccatga agtttgacct gtagaagccc
    40381 tttttcagca taggtcagag gaaaagatga gtcaggtgca aagcccatac tggcctgttc
    40441 ttcgatggta ttgtagcgtg ccatgcagcg ccagagggtt tcctcatcgg taccaaagat
    40501 aaagcgtacg cgctttttga actgaatacc ttggtccagc aagcttttta ctgcatagag
    40561 agctgcgagc gaagggcctt tatcatcttg gacaccacgt ccgaataccc agccgtcttt
    40621 gatagttgct tcaaatggcg gtgtctgcca atctgcttca tcacctgatg gaacaacatc
    40681 caaatgacag agaatggcca gaagctctgc tccctgaccg atttctgcat atccgtaata
    40741 acctttaggg tcaagatagg tagtgaaacc tatgtctcga caaatctcta aagttttttc
    40801 taggacatct tggattgctt gtccaaaagg tgttccattt tctccttcat tgagtactga
    40861 aggataggaa atcaaggttt ttaatgatat aagaaattca tctttaactt gatttgttat
    40921 atctattttc atggaatcac ctcactcact attttatagg aatggaagga aggttccaag
    40981 gagaagaagg gcgatggtca ctacaataat agcgactacg agtttgccca tgaatttcca
    41041 ccaagtacca atgttgatac gtccaagtgc aagagctccc atcacaatac cagatgttgg
    41101 tgcaatcaag ttcaagacac ctgaagcaga ttggtaagca gtgataatca agctaggacg
    41161 gacatttaca aattctccaa gtggagccat gatacccata gttgcgctgg caagaccaga
    41221 tgaagatggg atcaagaatg acataggtag atagaagata taagttacaa cgataaagac
    41281 ttgtgaagat agaccgctca agccttcttt accccagttg aggattgtat cggtaatcat
    41341 accgtcgttc atgataactt gaataccacg agcaatcgct acgatcaagg caacactgag
    41401 caagtcagca gcaccattca tgaaggaaga gataatctta tcttctttaa gaccataaat
    41461 aacaccaatc aggataccca taaaggcaaa gagcatggcg ccttctggga agtaccaagt
    41521 acctagtgca gaagtagatg aaccgacaat attaccaata actggaagac cagtcaacca
    41581 agcattaaag tcatcaaaaa tggtaacgcc aaggtctgtc catggaatga agctcaatac
    41641 catcaagatg aatgtcaaca caaataagaa gagaactgat ttttgtttgc tgctaagtgt
    41701 agattctaca gatgaagatt cttctacgtt aaagtgtttc aaatcttctt tgcgagtact
    41761 ataaaccagt gacttagtcg gatctttttg aatcttatcc gcataacggt aaacaaacca
    41821 agtactaaga gcagtcaagg taacccagaa aatcagacga agtacgatac cgtcccctgt
    41881 accaactccc gcagtcgctg aagcaatacc tgtcgcaaat ggattcagag tagatgccaa
    41941 acagccgatt tgagaaccga gcaaaataat tgcaacacca gtcaggctat caaaaccaac
    42001 ggccatcata actggcacaa ggagtggata gaaggccatt gtttcttccc ccataccata
    42061 agttgtacca ccgagggcaa acaaaggcat cagtaccaaa attaacattt tttcgcggcc
    42121 cttatacttc ttcacgatag aggcaatccc tacgtcaaga gcaccagttt tgttgacaat
    42181 gccaaggaaa ccaccaacca taaggatgaa gaaggctaca tcaatcgctg cgctcgtttc
    42241 tttaatgagc gaaccttcct ctggatgagt acctagcata gcccgaatcg gtgccatgag
    42301 gacatcccaa atcccttgtg gattttgagg ctgagcctcg taaatacctt ctataaaggc
    42361 ccccgcaggg ataaaccaag ttagcactgc cataatagca atgattatca ataatacggt
    42421 gtaagatgaa ggcatcttaa accctttttt agctttttca ctcatttgtt tttcctcctg
    42481 atgtctaaca aagtgtaaaa aaccaactac tttcttaaat aaacatttaa gaaaacgctt
    42541 tctatttata tttgttttac catattaaag tctaaaaaac taatatcttt tgaaatattg
    42601 tacatgtttt caagaataat ttctaatttg atataaagat actagaaata gaatacatct
    42661 tattagtaaa acaacttatc ctttttcaat aattgttccg ctttcagatt caatcaaggc
    42721 gcctagattt tcaagggaag taataactgc ttttccttct ggacgaccat tgacaaaagc
    42781 gatagctgct tctacttttg gaagcatgct acctggtgca aactgatctt gtttgatata
    42841 ttcttccagc tgggcaacat tcacatgttc caatttttcc tggtttggct tgttgtagtt
    42901 aacaaataca taatctacac ctgtcaaaac gatgaagagg tctgcatcaa ccaattctgc
    42961 caaacgttgg gaagcgaagt ctttatcaat aaccgcttcg acaccagtca aatgtccatt
    43021 gttttctttg acgacgggaa taccgccacc acctgcagct acgacgactt gaccattatt
    43081 taaaagagta cggatggttt caatttcttt gatgtcaaca ggttttggtg aggcaacgac
    43141 cttacgccag ccacggccag catcttcctt gaaagtcgct ccgctctttt cggcttctgc
    43201 ttttgcttct tcttctgaat agaaaggacc gattggttta ctcaagttaa caaaagctgg
    43261 atcattttta tctacgacaa cttgcgttac aacagaggca acattttttt cgatgccttc
    43321 atccaagaga gcattttgca aagcattttt caaccagaaa ccgatgctac cttctgtcat
    43381 agcgacaagt gagtcgagtg ggaaggcagg gttcttttca gagtctgatg ccaaatgttg
    43441 gagcaagaga ttcccaactt gaggtccatt accgtgagtg ataatcagat catctccatt
    43501 tttaatcaat tttacaagat gcttagctgt ttcaactaaa gcttcttgtt gagcctttgc
    43561 tgatgggtca gaagaaagaa tcgcatttcc tcccaaagct actacaattt tacgatttgc
    43621 cataaattct cctttatcac actcaataga atgcgtttag atttcaattt aatgattttt
    43681 cacatatttt ataagaaata atagattacc attatataaa agaggaccgg actaaagcta
    43741 ttagtcgcag ccctcatagc tgttggtaga cggtttatta tctaaaatta tactttagga
    43801 atataaaggt taccaagtgt agcagccata acagctttga tagtgtgcat acggttttct
    43861 gcttgatcga agtggcgagc gtacttgctg cggaagactt cgtctgttac ttccatttct
    43921 tctacaccaa atttttcagc aacgtcttta ccataaacag tgtgagtatc gtggaatgct
    43981 ggcaagcagt gtaggaagat caagttttca ttgcctgctt ttttaactaa gtccatattg
    44041 acttggtaag gtttaagaag agctacacgt tctgcgaatt tgtcttcttc acccattgat
    44101 acccaaacgt ctgtgtaaag aacgtctgca tctttaactg cttcatcagc atcttcagtg
    44161 atgagaacat gtgcgccact ttctttagca aatccttctg ccaattcaac gatttctttt
    44221 tctgggaaga gttcttttgg tgagaagatg tgaacattga caccaaggat agcacctgtt
    44281 acgagcaagc tgttggcaac attgttacgt ccatcaccac agtataccaa tgtcaagcct
    44341 tccaagcgac cgaagttttc ttgaacagtc aagtagtcag cgagcatttg agttgggtgc
    44401 cattcgtcag ttagaccgtt ccatactgga acgcctgaga attctgccaa ttcttcaacc
    44461 atacgttggc tgaatccgcg gaattcaatc ccgtcaaaca tacgtcccaa tactttagca
    44521 gtatcttcag tagattcttt tttacccaac tgaatatcat ttgctccgag gtattctggg
    44581 tgagcaccaa ggtcgatagc cgcagttgta aaggctgcac gagtacgagt agatgttttt
    44641 tcaaatagga gagcgatatt cttgccagca aggtagtggt gttgaatatt gcgttttttc
    44701 aaatctttca agtgagctga aagaccaata aggtattcta actctgcacg ggtaaagtct
    44761 ttttctgcta agaagctgcg tccttggaat actgaatttg tcattttatt atttcctctt
    44821 tctatttttt acattttcta ttgacgaata ccgaacagcg attacacttc ttcacgttca
    44881 aatggcatag acatacaacg aggtccacca cggccccgaa ccaattcact tccgcgaatc
    44941 ttaatcaagc gaagcccgta ttcttccaaa atcttattgg tcacggtatt gcggtcataa
    45001 acaactacca caccaggtgc gatggtcaaa gtgttagaac cgtcgttcca ttgttcacgc
    45061 gcagctgcta cgatattgcc accaccgcaa cgaatcaaat gaactttttc tacaccaagg
    45121 ttttgagcaa gaagttcagc taagtcacct ttctcttcaa caattttaag tttttcgttt
    45181 tcgtaagtaa ctgagtaaac gtgaaggtcg ccttcgattt ctgggtgaat agtgaacttg
    45241 tcatagtcta ccatagtgaa gacagtatcc aagtgcatga atttacggtt gttagcaaat
    45301 tcaaaggcca aaactttctt gaagccaaca tttttcttga agatgttgac caaaagtttt
    45361 tcgatagaag ctgcgtctgt acgttgagag atacctactg caaggacgtc tttagaaaga
    45421 actagctcgt ctccaccttc gatacgcgta tcttcttcac ggttgtagac caaatccact
    45481 tttccgccat agattgggtg gtatttgaag atatacttac cgtagagtgt ttcacggtta
    45541 cgagtgtctg caaacatgtg gttaagcgat acggcgtttc caattgttgc aaatgggtcg
    45601 cgagtgaaat agaggtttgg catcgggtca attgcaaatg gataatctga ttcaactaag
    45661 tcagttagat ctttagcttc gtcaggaatt tctggcaatt caactttttg aatcccagcc
    45721 attgtttttt caaccaattc ttggttgtcc ttgatgccgt gaagcaattc acgaatagca
    45781 accttagttt gacgatcacg gatgttggct tcgtctaagt attcctcgat aaattgatcg
    45841 cggatttctg gagaggtcaa tgattcagca gcgagttgtt ctaggtagag aacctcaatt
    45901 ccttcatcgc gaagagcttg ggcaaatgca tcatgttctt tttgagcatc ttccaagaaa
    45961 ggaatatcat caaaaagaag cctttcaaga tagtccggca acaagttttc taactccttg
    46021 cctggacggt gcaacataac ttttttcagt ttcccaattt ctgagaagac ctgaattgga
    46081 tgtgaagaca tgtattttcc tccttaaaaa ttttgacttg gcaccatttt gggtaccgct
    46141 tacatgtatg ttataacgca attcctaggt aatgtcaatg gctataattt ctcggaaaat
    46201 aatataaatt atgatattta gcacaatttt atgttattat acacaacata ggatggaata
    46261 catatataca aatgcataaa cttctattaa agaggatata aaattttttt aaaaaatttt
    46321 tcaaaaaata cacaaataac caaaaagtgt ccaattatca tctggttatc acttggatct
    46381 gtataaagag aaatgtttgt gtgaaaggat aaaaagatgc aacattcttt tgaagataga
    46441 ttttggagaa gcatttcttg ttcaattgta caaattatag aatcttttct gagtatttag
    46501 gaagagataa ttatcttatt gaccctcttt ttattttttg ttatagtcga cgaggtgata
    46561 gtttagaata atcacttatt cacaatctgt ggaaaagtct ggagagtgaa tggtcttcac
    46621 acaatgacct gaaagaagcc tgagaataat tatggagagt agcattctga gaggtgttag
    46681 cagaaccata tgacagagct gtttgaagag ggaatattga ggagaaaaat cctgagccta
    46741 ccagttggag ttggaaagag ctggctgtta gatcatggtt tattatccac aacctgtgga
    46801 taaccttgtg aacaagagaa gttgcaaaag aaggagatat ataacgatga agaaaatcaa
    46861 accgcatgga ccgttaccaa gtcagactca gctagcttat ctgggagatg aactagcagc
    46921 ctttatccat tttggaccta atacttttta taatcaggaa tggggaacag gtcaggagga
    46981 tcctgagcgc tttaacccga gtcagttgga tgcgcgtgag tgggttcgtg tgctcaagga
    47041 aacgggcttc aaaaagttga ttttggtggt caagcaccac gatggctttg tcctttatcc
    47101 gacagctcac acagattatt cggttaaggt cagtccttgg aggagaggaa agggcgactt
    47161 gctccttgaa gtatcccaag ctgccacaga gtttgatatg gatatggggg tctacctgtc
    47221 accgtgggat gcccatagtc ccctctatca tgtggaccga gaagcggact acaatgccta
    47281 ttatctggct cagttgaagg aaatcttatc aaatcctaac tatgggaatg ctggtaagtt
    47341 cgctgaggtt tggatggatg gtgctagagg ggaaggggcc cagcaggtca attatgaatt
    47401 tgaaaaatgg tttgaaacca ttcgtgactt gcagggcgat tgtttgattt tttcaacaga
    47461 aggcaccagt atccgctgga ttggcaatga acgagggtat gcaggtgatc cactgtggca
    47521 aaaggtgaat cctgataaac taggaacaga agcagagctg gactatcttc agcacgggga
    47581 tccctcgggc acgatttttt caatcggaga ggcagatgtt tccatccgtc caggctggtt
    47641 ctaccatgag gatcaggatc ctaagtctct cgaggagttg gtcgaaatct actttcactc
    47701 agtagggcga ggaactccac tcttgcttaa tattccgccg aatcaagctg ggctctttga
    47761 tgcaaaggat attgaacgac tttatgaatt tgcgacctat cgcaatgagc tctataaaga
    47821 agatttggct ctgggagctg aggtatctgg tccagctctt tccgcagact ttgcttgtcg
    47881 ccatttgaca gacggccttg agaccagctc ttgggcaaac gatgcagact tgcccatcca
    47941 gttagaactc gacttaggtt ctcctaaaac ttttgatgta attgagttaa gagaagattt
    48001 gaagctaggg caacgaatcg ctgcttttca tgtgcaagta gaggtggatg gtgtctggca
    48061 ggaatttggc aggggcttca cagttggtca taagcgcctc ttgcgaggtc cgctagtaga
    48121 ggcacagaag gtgcgcgtga tgattaccga ggcacaatct attcctgtat tgaccaagat
    48181 ttccctttat aaaactcctg gattatcaaa aaaagaagtt gttcaggaac tagcatttgc
    48241 agaaaaaagc ctagctgtgg caaagggaga aaatgcctat tttacagtta agcgcagaga
    48301 atgtagtggt cctttagaag ctaagatttc gattcaaccg gggacaggtg tccatggtgt
    48361 cgcctatcag gatgagattc aagtccttgc gtttcaagct ggtgagactg aaaaaagtct
    48421 gacgctacca accttgtatt tcgcaggaga taaaaccttg tatttctatc tgaacctaac
    48481 ggtggatggt cagcttgtgg atcaacttca agtccaagtt tcataaaaga agaacctttg
    48541 cgcgatgcaa aggttctttt ggttattagt gacttggtaa ccagctgagg gtgaaagtta
    48601 gttgttcagc ttttaagagg tcttggtgtt gaatagttga tacgagtatt ttgtccagtc
    48661 ggcattcttt gacaaagtta aaatggttgt ggttttgttt agtatggata tccagccatt
    48721 tatcttcttt agctaggtag actcgtagat ggtcaaagag agggattccg aggtcatagc
    48781 ttggttttcc tggacaggtt ggataaaatc cgagagctga ccagatgtac caagcagaga
    48841 gactaccatt gtcttcatct ccaggatagg cttcccaact tgggtgaaaa gctttctgac
    48901 ggagcgtctt gataagaagg gcagtgtagt cagggtaatc gctgtagcgg aagagataag
    48961 gaatgtggaa actaggctgg ttggaaatgg ctatttgtcc aaaaggagca gtagccatct
    49021 cgctcatttc gtgaatttcg taaccatagc ctgttgtttc aaagagggga gcatcttgac
    49081 aggctttcaa aagatagttg ctaaaggttt cttttccacc catcagttgg attaagccag
    49141 ggatgtcgtg gagaacgcct aaagtagctt gaatggcaga gcattcagcg tagtctcgcc
    49201 cccaactata aggagagaag tcagggtgaa agtttccttg attgtctcgt gctcgcatgt
    49261 aacctgtctc agcgtcaaat agctggcggt aattttgtga agcagccttg taggtttcag
    49321 cgatttctat gttctctagt tttttggcac agctggcgat acaaaagtca ctataggcat
    49381 agtctagagt atggctaaca ctttcatggt ggtcggtaga gaggtaacct agttcttggt
    49441 attgggctag tccgtggcgg ccattgatgc cgagagggtc ggctttgctg gctgtttcga
    49501 gcatggcttg gaagagttct ccttctaggt caggggccat gtccttgcag gcgctatctg
    49561 cgataatacc gtctaaaagt gtacctggca tcataccccg ttcatctgga gccagccatt
    49621 ttggaaggaa accagtatcg cggtagctat tgaggaaacc ttctaaaaag cgttgatagt
    49681 gctccggtat gataagggca aagaggggga aggtggtgcg gaaggtatcc cagaaaccat
    49741 tgttgctaaa gaggacacca ggcttgacag taccagtagc cagatccatg tggatggctt
    49801 gccctgactc atcaacctca taaaaagtct gtgggaagag gaagagtctg tagaggcagt
    49861 ggtcaaagaa ggttcggtca gcctctcctg tctctataat gtcaaaacga tggaggagat
    49921 tttcccaatc cgcttgggca cttgatttac agctatcaaa atcttcttga ggtagattga
    49981 ttagagcttg agaaggagag atgaaagaag tggctagttg catctcggtt tgactactta
    50041 ctaagtcaat tcgccagtct ccagcttctt ggctgatagc aagaatatcc gtgttcattt
    50101 gcagggcagt gaacatcgtt agcgaatttt tgttagtttc agttttacct tcttgtcgca
    50161 gggcaagagt ccgcttatct acttgctcta ctgtcagttc atctgctgcg tgaagataga
    50221 gggagagggc tttgccttgc ttttgattca aacgaataga agcaccatag caagttggtg
    50281 tgagctgggt ttcaatctga taacgcagag aaaagagctt caaatagtga ggctggaagc
    50341 aagctttatc tatatcataa gaagactggc ggtgaaagag gctgtctccc cccagttgac
    50401 tggtgacagg tgtcagaagg agccaagagt agtccccaat ccaaggactg ggctggtgag
    50461 ttaatcgaat cccctgaaag ataggcagat gcggatcaaa aaaccaagat ccatcctggt
    50521 cactggtctg gggcacaaag taattcatcc caaaaggcac gcctgtgtat ggcagggtat
    50581 ttccccaaga gaaggcatgc ttgctagcag taccaaagcg ggtatcgatg gtttcaagta
    50641 gtggtttcat agtctttcct ttagctgttt ttctacatta tatcagaaaa agagggcctt
    50701 tagaaaagga gtttcaaaaa taactatttt gtagaaaaat gactatcatt tgtgtatgta
    50761 ttttctgtct caaaagctat atactgaaca tgaaacttgt ttgaaagagg gaattgcacg
    50821 atgatttatc cgaaagaaat tgttagagaa tggctagatg aagtagcaga gcgggctaag
    50881 gaccatccag agtgggtgga tgttttcgag cgttgctaca ccgatacctt ggacaatacg
    50941 gttgaaatct tagaagatgg ttcaactttt gtcttgactg gggatattcc tgctatgtgg
    51001 cttcgggatt cgacagccca actcagaccc tacctgcatg tagctaaaag agatgccctc
    51061 ctgcgtcaga ccattgcagg tttggtcaaa cgtcagatga ccttggtact caaggatcct
    51121 tatgccaatt ccttcaacat agaggaaaac tggaaggggc accacgagac cgaccacacc
    51181 gaccttaatg gctggatttg ggaacgcaag tatgaggtgg actcgctttg ctatcctttg
    51241 cagttggctt atctcctctg gaaagaaact ggcgagacta gtcagtttga tgagactttt
    51301 gtcgcagcga ctaaggaaat tctccatcta tggacagttg aacaagacca caagaactct
    51361 ccttatcgtt ttgtccgaga tacggaccgt aaggaagaca ccttggtaaa tgatggcttt
    51421 ggacctgact ttgcagtgac aggtatgact tggtcagcct ttcgtccgag tgatgactgt
    51481 tgccagtata gttacttgat tccgtcaaat atgtttgctg tagtagtctt gggttatgtg
    51541 caagaaatct tcgcagcatt aaacctagct gatagccaga gtgttattgc tgatgccaag
    51601 cgtcttcagg atgaaatcca agaaggaatc gaaaactacg cttacaccac caacagcaag
    51661 ggcgaaaaga tttacgcttt tgaagtagat ggcctaggaa atgccagcat catggatgat
    51721 ccaaatgtac caagtctact agctgcgccc tatctgggct actgttcgat cgatgatgaa
    51781 gtgtatcaag ccactcgccg taccattctg agctctgaaa atccatactt ctaccaagga
    51841 gaatacgcta gcggtctcgg aagttctcat accttctatc gctatatctg gccaatcgcc
    51901 ctttctatcc aaggattgac aacaagagat aaggcagaga aaaaattctt gctggatcag
    51961 ctggttgcct gcgatggtgg tacaggtgtc atgcacgaaa gcttccacgt agatgatccg
    52021 accctctact ctcgtgaatg gttctcctgg gctaacatga tgttctgtga gttggtcttg
    52081 gattacttgg atattcgcta aggggctcgc tttagctcaa ccgattctta tcagaatcac
    52141 aagtttacat ttaaaacgtt aaaatttaaa tttagaatga ggttttactt catggaaaat
    52201 gttgttgtac atattatctc acatagtcac tgggaccgtg agtggtactt gccttttgaa
    52261 agccatcgta tgcagttggt ggaattgttt gacaatctct ttgatctctt tgaaaatgac
    52321 cctgagttca agagtttcca cttggatgga caaactattg tccttgatga ctacttacaa
    52381 attcgccctg aaaatcgcga caaggtccaa cgctacattg acgagggcaa acttaaaatt
    52441 ggtccctttt acatcttgca ggatgactac ttgatctcca gtgaagccaa tgtccgcaat
    52501 accttgattg gtcaacaaga agctgccaaa tggggtaaat caacccagat tggctacttt
    52561 ccagatacct ttggaaatat gggacaagcg cctcaaattc ttcaaaaatc aggcattcac
    52621 gtggcggcct ttggtcgtgg tgtgaagccg attggatttg acaaccaagt ccttgaagat
    52681 gagcagttta catcccagtt ttcagaaatg tactggcagg gtgtggatgg tagtcgtgtt
    52741 ttaggtattc tctttgccaa ctggtacagt aatgggaatg aaatcccagt tgacaaagat
    52801 gaggccttga ccttctggaa acaaaaattg tcagatgtgc gtgcctacgc ttcgaccaac
    52861 caatggttga tgatgaacgg ctgtgaccac cagcctgtac agaaaaatct gagcgaagcc
    52921 attcgtgtgg caaatgaact cttcccggat gtaatctttg ttcatagttc ttttgatgaa
    52981 tatgttcaag ctgtagaagg tgcgcttcct gaacacttat caactgttac aggcgagttg
    53041 accagtcagg aaacagatgg ctggtacaca cttgccaaca cttcttcatc ccgcatttac
    53101 ctaaaacaag ccttccaaga aaatagcaac ctcctagagc aagtggtaga acccttgact
    53161 attatcactg gtggacacaa ccacaaggac cagttgacct atgcttggaa aacacttttg
    53221 cagaatgcgc cacatgatag tatctgtggc tgtagcgtgg acgaagttca ccgcgagatg
    53281 gaaacgcgtt ttgccaaggt caaccaagta ggaaactttg ttaaaagtaa tttgctcaac
    53341 gagtggaagg gtaaaattgc tacggataag gctcaaagtg actatctctt tactgtcatt
    53401 aacacaggct tgcatgataa ggtcgatact gtcagcacag tgattgatgt ggcgacttgt
    53461 gatttcaagg aattgcaccc aacagaaggc tacaaaaaga tggctgctct tatcttgcca
    53521 agttaccgtg tggaggactt ggatggtcgt cctgtagagg ttacaatcga agacctcgga
    53581 gctaattttg aatacgattt accaaaagat aagttccgcc aagctcgtat tgctcgacaa
    53641 gtgcgcgtga ccattccagt tcacctagca ccgctttctt ggacaacctt ccaattgctg
    53701 gaaggagaac aagaacaccg tgagggtatt taccaaaacg gagtgattga tacaccattc
    53761 gtaacggtga gtgtggatga caacatcaca gtctatgata agacaactca cgaagcctat
    53821 gaagatttta tccgcttcga agaccggggt gacatcggaa acgagtatat ctatttccaa
    53881 ccaaaaggaa cagagccaat ctttgcagag cttaagggcc acgaggtctt ggaaaacaca
    53941 gatcgctatg ctaaaatctt gctcaaacat gaattgaccg tgcctgtcag tgcggatgaa
    54001 aagctagaag aagagcaaca aggtatcatc gagtttatga agcgtgaggc tggacggtca
    54061 gaagaattga caaacattcc tctggaaact gagttgattg tctttgttga caatccacaa
    54121 atccgcttca agactcgctt tactaacact gccaaggatc accgtatccg tctcttggtc
    54181 aagactcata acacgcgtcc aagcaatgat tctgaaagta tctatgaggt ggtgacacga
    54241 ccaaacaaac cagctgcttc atgggaaaat cctgaaaatc ctcaacacca acaagctttt
    54301 gtcagtctgt atgacgatga aaaaggggtg actgtatcca acaagggatt gaatgaatac
    54361 gaaatccttg gggataacac cattgccgtg accattttgc gtgcatcagg tgagctaggt
    54421 gactggggct acttcccaac gccagaagca caatgcttgc gtgagtttga agtcgaattt
    54481 gcgattgaat gccaccaagc ccaagaacgc ttctcagcct atcgtcgtgc caaagccttg
    54541 cagacaccgt ttaccagcct tcagcttgct agacaggaag gaagcgtggt tgcgactggt
    54601 agcctcttga gccattctgt tctcagcata ccgcaagttt gtccaacagc ctttaaagtg
    54661 gcggaaaatg aagaaggcta tgtcctccgt tactataata tgagtcaaga aaatgtgcgc
    54721 atatcagaac atcaacaaac cattcttgac ttacttgagc gaccatatcc agttcattca
    54781 ggactattgg ctccacaaga gattcgtaca gaattcatca aaaaagaaga aatttaattt
    54841 caaaaagtaa acatcaaaag aaaggagggg cgaaaaagta agaactaact gctgattcgc
    54901 ccctttttat ggtaaaaaca atgaccattg caacgattga tatcggaggg actgggatta
    54961 agtttgccag tctgactcct gatgggaaaa tactggataa gacaagtatt tcaacgcctg
    55021 aaaacttgga ggatttacta gcgtggctag atcaacgctt gtcagaacag gattacagtg
    55081 ggattgctat gagcgttcca ggtgcggtca atcaagagac aggtgtgatt gatggcttca
    55141 gtgcggtgcc ctacatccat ggcttttctt ggtatgaggc gcttagctct tatcagctac
    55201 ctgtccattt agaaaatgat gccaactgcg ttggactcag tgaactacta gctcatccag
    55261 agcttgaaaa tgcagcctgt gtcgtgattg ggacagggat tggcggagcc atgattatca
    55321 atggtagact ttatcgaggt cgccacggtc tgggtggaga atttggctac atgacaaccc
    55381 ttgcccctgc tgaaaaactt aataactggt cgcaactagc atcaactggg aatatggtac
    55441 gatacgtgat tgaaaaatct ggtcatactg attgggacgg tcgcaagatt taccaagagg
    55501 ccgcagctgg taatgctctt tgtcaagaag ccattgagcg catgaaccgc aatctgacgc
    55561 aaggcttgct caatatccag tatctgatcg atccagatgt catcagtctg ggtggctcta
    55621 tcagtcaaaa tccagatttt atccaaggtg ttaagaaggc tgttgaagac tttgtcgatg
    55681 cctacgaaga atacacggtc gcaccagtta tccaggcctg cacctatcac gcagatgcca
    55741 atctctacgg tgcccttgtc aactggctac aggaggaaaa gcaatggtaa gatttacagg
    55801 acttagtccc aaacaaacgc aagctattga ggttttaaaa ggtcacattt ctctaccaga
    55861 tgtggaagtg gctgtcactc agtctgacca agcctctatc tctatcgagg gtgaggaagg
    55921 tcactatcaa ttgacctacc gcaaacctca ccaactttat cgtgccttat ccttgttggt
    55981 aacagttcta gcagaagctg ataaagtaga gattgaggaa caagcagctt acgaagattt
    56041 ggcttacatg gttgactgtt ctcgaaatgc ggtgctgaat gtggcttctg ccaagcagat
    56101 gattgaggtc ttggctctca tgggctactc aacctttgag ctttacatgg aagacactta
    56161 ccagattgaa ggacagcctt actttggcta tttccgtgga gcttattcag cagaggagtt
    56221 gcaggaaatc gaagcctatg ctcaacagtt tgacatgacc tttgtaccat gcatccagac
    56281 cttggcccac ttgtcggcct ttgtcaaatg gggtgtcaag gaagtgcagg agctccgtga
    56341 tgtagaggac attcttctca ttggcgaaga aaaggtttat gacctgattg atggcatgtt
    56401 tgccacgttg tctaaactga agactcgcaa ggtcaatatc gggatggacg aagcccactt
    56461 ggttggtttg ggacgctacc tgattttgaa cggtgttgtg gatcgtagtc tcctcatgtg
    56521 ccaacacttg gagcgcgtgc tggatattgc tgacaaatat ggtttccact gccagatgtg
    56581 gagtgatatg ttcttcaaac tcatgtcagc ggatggccag tacgatcgtg atgtggaaat
    56641 tccagaggaa actcgtgtct acctagaccg tctcaaagac cgtgtgactc tggtttactg
    56701 ggattattat caggatagcg aggaaaaata caaccgtaat ttccgcaatc atcacaagat
    56761 tagccatgac cttgcatttg cagggggagc ttggaagtgg attggcttta cacctcacaa
    56821 ccattttagc cgtctagtgg ctatcgaggc taataaagcc tgccgtgcca atcagattaa
    56881 agaagtcatc gtaatgggtt ggggagacaa tggtggtgaa actgcccagt tctctatcct
    56941 accaagcttg caaatctggg cagaactcag ctatcgcaat gacctagata gtttgtctgc
    57001 gcatttcaag accaatactg gtctaacggt tgaggatttt atgcagattg accttgccaa
    57061 cctcttacca gacctaccag gtaatctcag tggcatcaat cccaaccgct atgtctttta
    57121 tcaggatgtt ctctgtccga tacttgaccg acacatgaca cctgaacagg acaagccaca
    57181 cttcgctcag gcggcgggaa ctattgctga cattaaagaa aaagctggaa actatgctta
    57241 tctctttgaa actcaggccc agttgaatgc tattttaagt agcaaagtag atgtgggacg
    57301 acgcattcgt caggcctacc aagcggatga taaagaaagt ttacaacaaa tcgccagaca
    57361 agaattacca gaacttagaa gccaaattga agacttccat gccctcttta gtcaccaatg
    57421 gttgaaagaa aacaaggtct ttggtttgga tacagttgac atccgtatgg gcggactctt
    57481 gcaacgcatc aaacgagcag aaagccgtat cgaggtttat ctggctggcc agcttgaccg
    57541 catcgacgag ctggaagttg aaatcctacc atttactgac ttctacgcag acaaggattt
    57601 cgcagcaact acagctaacc agtggcatac cattgcgaca gcttcgacga tttatacgac
    57661 ttaatactct tcgaaaatct cttcaaacca cgtcagcttc catctacaac ctcaaaacag
    57721 tgttttgagc agcctgcagc tagcttccta gtttgctctt tgattttcat tgagtataaa
    57781 aacaagaaca ccttgcttgg cgcagggtgt ttcgcgtgaa acagaagaat tatctggttt
    57841 caaatgctac agttagacaa acttatgata aaatagcaga aagtgaatgt ttcctaagag
    57901 caattctatc gatgagcaat tggaggtatt atgctacact taaaattagt aaaacaagaa
    57961 atagaagctg aaaagccagc atctgtagaa gcttggatca tttccgtcaa atttaaaaaa
    58021 ggttgctacc gacatatata gattccaaaa acaaaaacgt tagcggaact agcagatgtg
    58081 attttatggg gttttgattt tgcaaatgat catgctcacg catttttcat ggataatgtt
    58141 gagtggagtc atgcagattc ttactttctt agctttgtta gtgacgatgt tgaagaacgt
    58201 tacacagaaa atgtctatct ggatagccta agtgtcaaac aaaaatttaa gtttattttc
    58261 gacttcggtg atgaatggcg ttttgaatgc caagtactga gagaaatcga gacagaggac
    58321 gaagaagctt atctcgtacg ttcggttgga acgtcgccag aacaatatcc agattatgat
    58381 ggttttgact atgaagaatg gtaaaattga aatctaaaaa acaattggaa tcagtctgtg
    58441 taggcttagt atttcaatag acttcctgca aaactagaat cctaattcat gattgataat
    58501 accagcactc aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga
    58561 aaacatttta aacgttttta ctttggcaaa gatgttctca accttgcttc tctccttaga
    58621 tagcgcatgg ttacaggctt tatcttcaac tgttagcggc ttgagtttgc tggatttacg
    58681 tggagtttgt gcttgaggat atatcttcat gagcccttga taatcactgt cagccaagat
    58741 tttaccagaa tgattcgcta attgtttttt tagggcgatt gatttgtact tccgtcgcat
    58801 caatcattac cgtgtcctca gaactgagag gagttcttga aatcgtaaca ccactttgaa
    58861 caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtga ataccaaaat
    58921 cagccgcaat ttcttcataa gtgcggtatt ctcgcacata ttgaagagtg gccataagaa
    58981 ggtcttctag gcttaattta ggttttcgtc caccttttgc gtgtttaagt tgataatctg
    59041 tttttaacac agctaacatc tctttaaaag tggtacgctg aacaccaaca agacgcttaa
    59101 atcgtgtatc agttaattgt ttacttgctt cataatttcg cagggagtct attgactctt
    59161 tggtaggtgt caatgttttt ttcatctata ccgagaatta ttttcccgcc atttgtattt
    59221 gcaaatgctg agtaggtttc ccagaaagac tctggaagat tgtttttagc ttttttgtat
    59281 tctaaatcaa ccccttcaaa ttttaagtcc atatttttcc tttacatctg ttttttgtgg
    59341 ttctggtatt tgttcaagtt gagtgataat atagcgaatt gaatttcgag agtttttact
    59401 cagttaattt cttttttaac ccgctttaat ttctttttta acacgtgtta aaaaagaaat
    59461 taaagcgggt taatt
//
LOCUS       DAVLAQ010000005        57132 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000005 DAVLAQ010000000
VERSION     DAVLAQ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.005"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            49..1296
                     /locus_tag="VXB71_000289"
     CDS             49..1296
                     /locus_tag="VXB71_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0450465.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            1374..2663
                     /locus_tag="VXB71_000290"
     CDS             1374..2663
                     /locus_tag="VXB71_000290"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0450466.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETISMAAYFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            2918..3232
                     /locus_tag="VXB71_000291"
     CDS             2918..3232
                     /locus_tag="VXB71_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450467.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     FQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            3242..3448
                     /locus_tag="VXB71_000292"
     CDS             3242..3448
                     /locus_tag="VXB71_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0450468.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            3448..3645
                     /locus_tag="VXB71_000293"
     CDS             3448..3645
                     /locus_tag="VXB71_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450469.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNLYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            3648..4370
                     /locus_tag="VXB71_000294"
     CDS             3648..4370
                     /locus_tag="VXB71_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0450470.1"
                     /translation="MKKKRRLLFLMSIVLGMFVGMFKARVESHEIILDVKALMPWISA
                     ICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITG
                     VAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFAT
                     PKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            4382..5023
                     /locus_tag="VXB71_000295"
     CDS             4382..5023
                     /locus_tag="VXB71_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0450471.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVAFAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            5041..5271
                     /locus_tag="VXB71_000296"
     CDS             5041..5271
                     /locus_tag="VXB71_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450472.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            5307..5387
                     /locus_tag="VXB71_000297"
                     /pseudo
     CDS             5307..5387
                     /locus_tag="VXB71_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5668..7431
                     /gene="aspS"
                     /locus_tag="VXB71_000298"
     CDS             5668..7431
                     /gene="aspS"
                     /locus_tag="VXB71_000298"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0450473.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            7409..8350
                     /locus_tag="VXB71_000299"
     CDS             7409..8350
                     /locus_tag="VXB71_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0450474.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(8515..8595)
                     /locus_tag="VXB71_000300"
                     /pseudo
     CDS             complement(8515..8595)
                     /locus_tag="VXB71_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(8731..9717)
                     /locus_tag="VXB71_000301"
     CDS             complement(8731..9717)
                     /locus_tag="VXB71_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0450475.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(9727..10527)
                     /locus_tag="VXB71_000302"
     CDS             complement(9727..10527)
                     /locus_tag="VXB71_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0450476.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(10780..11622)
                     /locus_tag="VXB71_000303"
     CDS             complement(10780..11622)
                     /locus_tag="VXB71_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0450477.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(11624..12916)
                     /locus_tag="VXB71_000304"
     CDS             complement(11624..12916)
                     /locus_tag="VXB71_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0450478.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(13027..14298)
                     /locus_tag="VXB71_000305"
     CDS             complement(13027..14298)
                     /locus_tag="VXB71_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0450479.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            14848..16365
                     /gene="malQ"
                     /locus_tag="VXB71_000306"
     CDS             14848..16365
                     /gene="malQ"
                     /locus_tag="VXB71_000306"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0450480.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            16391..18649
                     /locus_tag="VXB71_000307"
     CDS             16391..18649
                     /locus_tag="VXB71_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEV0450481.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(19693..20265)
                     /locus_tag="VXB71_000308"
     CDS             complement(19693..20265)
                     /locus_tag="VXB71_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450482.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(20887..21735)
                     /locus_tag="VXB71_000309"
     CDS             complement(20887..21735)
                     /locus_tag="VXB71_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0450483.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            21887..22165
                     /locus_tag="VXB71_000310"
     CDS             21887..22165
                     /locus_tag="VXB71_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450484.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22167..24230
                     /locus_tag="VXB71_000311"
     CDS             22167..24230
                     /locus_tag="VXB71_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0450485.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTKELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(24308..25564)
                     /locus_tag="VXB71_000312"
     CDS             complement(24308..25564)
                     /locus_tag="VXB71_000312"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0450486.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            25706..28171
                     /locus_tag="VXB71_000313"
     CDS             25706..28171
                     /locus_tag="VXB71_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0450487.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            28236..29147
                     /locus_tag="VXB71_000314"
     CDS             28236..29147
                     /locus_tag="VXB71_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0450488.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            29377..30075
                     /gene="dapD"
                     /locus_tag="VXB71_000315"
     CDS             29377..30075
                     /gene="dapD"
                     /locus_tag="VXB71_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0450489.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            30143..31273
                     /locus_tag="VXB71_000316"
     CDS             30143..31273
                     /locus_tag="VXB71_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0450490.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            31285..31824
                     /locus_tag="VXB71_000317"
     CDS             31285..31824
                     /locus_tag="VXB71_000317"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0450491.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            31808..32485
                     /locus_tag="VXB71_000318"
     CDS             31808..32485
                     /locus_tag="VXB71_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0450492.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(32557..33456)
                     /gene="galU"
                     /locus_tag="VXB71_000319"
     CDS             complement(32557..33456)
                     /gene="galU"
                     /locus_tag="VXB71_000319"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0450493.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(33478..34494)
                     /locus_tag="VXB71_000320"
     CDS             complement(33478..34494)
                     /locus_tag="VXB71_000320"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0450494.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            34706..35146
                     /locus_tag="VXB71_000321"
     CDS             34706..35146
                     /locus_tag="VXB71_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0450495.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(35269..35685)
                     /locus_tag="VXB71_000322"
     CDS             complement(35269..35685)
                     /locus_tag="VXB71_000322"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0450496.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(35753..36403)
                     /gene="phoU"
                     /locus_tag="VXB71_000323"
     CDS             complement(35753..36403)
                     /gene="phoU"
                     /locus_tag="VXB71_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0450497.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(36418..37170)
                     /gene="pstB"
                     /locus_tag="VXB71_000324"
     CDS             complement(36418..37170)
                     /gene="pstB"
                     /locus_tag="VXB71_000324"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0450498.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(37172..37987)
                     /gene="pstA"
                     /locus_tag="VXB71_000325"
     CDS             complement(37172..37987)
                     /gene="pstA"
                     /locus_tag="VXB71_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0450499.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(37980..38843)
                     /gene="pstC"
                     /locus_tag="VXB71_000326"
     CDS             complement(37980..38843)
                     /gene="pstC"
                     /locus_tag="VXB71_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0450500.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(38961..39836)
                     /locus_tag="VXB71_000327"
     CDS             complement(38961..39836)
                     /locus_tag="VXB71_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0450501.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(40003..41334)
                     /locus_tag="VXB71_000328"
     CDS             complement(40003..41334)
                     /locus_tag="VXB71_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0450502.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(41335..42042)
                     /locus_tag="VXB71_000329"
     CDS             complement(41335..42042)
                     /locus_tag="VXB71_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450503.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(42126..42602)
                     /locus_tag="VXB71_000330"
     CDS             complement(42126..42602)
                     /locus_tag="VXB71_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0450504.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            42609..43136
                     /locus_tag="VXB71_000331"
                     /pseudo
     CDS             42609..43136
                     /locus_tag="VXB71_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(43451..45142)
                     /locus_tag="VXB71_000332"
     CDS             complement(43451..45142)
                     /locus_tag="VXB71_000332"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0450505.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            45278..45724
                     /gene="argR"
                     /locus_tag="VXB71_000333"
     CDS             45278..45724
                     /gene="argR"
                     /locus_tag="VXB71_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0450506.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            45775..48309
                     /gene="mutS"
                     /locus_tag="VXB71_000334"
     CDS             45775..48309
                     /gene="mutS"
                     /locus_tag="VXB71_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0450507.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            48456..50150
                     /gene="patA"
                     /locus_tag="VXB71_000335"
     CDS             48456..50150
                     /gene="patA"
                     /locus_tag="VXB71_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0450508.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(50480..50743)
                     /locus_tag="VXB71_000336"
                     /pseudo
     CDS             complement(50480..50743)
                     /locus_tag="VXB71_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            50941..52707
                     /gene="patB"
                     /locus_tag="VXB71_000337"
     CDS             50941..52707
                     /gene="patB"
                     /locus_tag="VXB71_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0450509.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            52846..53535
                     /locus_tag="VXB71_000338"
     CDS             52846..53535
                     /locus_tag="VXB71_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0450510.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            53539..53718
                     /locus_tag="VXB71_000339"
     CDS             53539..53718
                     /locus_tag="VXB71_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450511.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            53705..55054
                     /locus_tag="VXB71_000340"
     CDS             53705..55054
                     /locus_tag="VXB71_000340"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0450512.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            55178..56638
                     /locus_tag="VXB71_000341"
     CDS             55178..56638
                     /locus_tag="VXB71_000341"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0450513.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            56652..57083
                     /locus_tag="VXB71_000342"
     CDS             56652..57083
                     /locus_tag="VXB71_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0450514.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT        16685 a        10862 c        12424 g        17161 t
ORIGIN      
        1 ctaaagctat tcttgatgta gaacttagaa caagaaggga gattatctat gaaactattg
       61 tttagaaatc cagcttatag aattttgact ttatcacgct tcttcaatgc ttttggtgct
      121 tcgattttca acctggtctt tatcgtctat gcatcgacct tgtcacaagc atcttttgct
      181 gttgctatgg cgaatattgt catgattctt ccgaccctct ttacagtttt tgtagggatt
      241 cgggcagatt acacgaggga caaggtcaaa tggatggtct atagcggttt gtttcaggcg
      301 gttctatttt tcctagcagc cctagttgtt cagcaagcta gtctctttgc cttttctagc
      361 ctgtgtttga tcaatgtcat tagtgatgtc atcagtgatt ttgcaggtgg cttgcgcatg
      421 cctcttatta aggaaaaagt agctgaagat gatctgatgg aggcttattc tttttcacag
      481 ttcatcacct atatttcagc tattggtggt caagctttcg gagtctggct cttagctcta
      541 tcggtcaaca atttttctct cgttgcggga atcaatgcct gctttttcct agtatcagcc
      601 actatcctct ttttaggaaa aagcaaattg agcctgtcaa tgtcatctgc tgatggtgaa
      661 aacttaaaaa atgagaagct ttctatcaaa gaccagttcc taacaattta ccgaaattta
      721 cgtctcgttt ttcttaaaag tgggcagaaa aactttggtt ttatgctctt tgctgtcttg
      781 cttattaatt ccttgggtgg cgctttgggt ggaatttata atatcttctt tttgagccat
      841 tctctcttga atttttctta tacagaggca ctatttatca atcaattctg tgttttagta
      901 gcaatcatca tcagtagcct tacgggcaat gattattttg ggaagcagtc cttgcctaga
      961 ttgatgatgt gggcgaccgt aggacttagt ctagttggtt tggctaattt attcaatcaa
     1021 gtcgtgcttg gtttgctatt tctcttcttt accctgtatg tgtctggtaa agttcaacca
     1081 aagattagtg ccatgctcat gaaaaatcta gctccagagg ttctagctcg tactagtaat
     1141 tttttaggtc tattgtttac cttatccata cctgtgggaa cagcttgttt ttcactagta
     1201 gccgtatgga atatacagtt gacttggatg ctatttgttg gtctttcctt gctagctatt
     1261 tttttgacaa ttcttaatct caaaaatgat atctaaatcc taattttttt cttactgttt
     1321 taatcccttt atttgtggta aaataagact attaagttta aagaggattc cctatgaaat
     1381 tacaaaaacc aaaaggaacg caggatattt tacctgctga atctgctaag tggcagtacg
     1441 ttgagggctt tgcccgtgag attttcaagc gctataacta tgcagaagtg cgcacgccta
     1501 tttttgagca ttacgaggtt atcagtcgct ctgtcggaga tacaacggat atcgtaacca
     1561 aggaaatgta cgatttttat gacaagggtg accgtcatat taccctccgt ccagaaggaa
     1621 ctgcgcccgt tgtccgttcc tatgtggaaa ataaactctt cgccccagaa gtgcaaaagc
     1681 caagcaagtt ctactatatg ggacctatgt tccgttatga gcgtccacag gcagggcgct
     1741 tgcgccaatt ccaccagatt ggtgttgagt gttttggctc tagcaatcca gctaccgatg
     1801 tggaaacaat ctctatggca gcctattttt tgaaggaaat cggtattcaa ggtgtcaaat
     1861 tgcacctcaa cactcttgga aatcctgaga gccgtgcagc ctaccgccaa gccttgattg
     1921 actatttgac accgctcaag gagaccttgt ctaaggatag ccaacgtcgc ttggaggaaa
     1981 atcctcttcg tgtcttggac tctaaggaaa aagaagacaa ggtggcagta gagaatgcgc
     2041 cgtctatctt ggactttctt gatgaagaaa gccaaactca ttttgatgct gtgcgtcaga
     2101 tgttggaaaa tcttggagta gattacatca tcgataccaa tatggtgcgt ggtctggact
     2161 actacaacca caccattttc gagtttatca cagagattga gggcaatgac ttgacagtct
     2221 gtgcgggtgg tcgctacgat ggtttggttg cttactttgg aggccctgaa actgctggat
     2281 ttggttttgg gcttggtgta gagcgcctgc ttctcatcct tgaaaaacaa ggcgtggccc
     2341 tccctatcga aaacgcccta gatgtctata tcgcagtctt gggtgatgga gcaaatgtca
     2401 aagccctaga actagtccaa gctcttcgcc aacaaggttt caaagcagag cgtgattacc
     2461 tcaaccgtaa gctcaaagct cagttcaagt cagcagatgt ctttgcggct aagaccctca
     2521 tcaccctagg agagagcgaa gtcgaaagcg gacaagtgac ggtcaagaac aaccaaaccc
     2581 gagaagaagt gcaagtgtca cttgagacaa tcagccaaaa cttctcagaa atctttgaaa
     2641 aactaggatt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
     2701 ctcaaaacat ggttttgagg ttgtagatga agctgacgtg gtttgaagag attttagaag
     2761 agtattaatg atagataaag tggtcaggaa cttactcctg acctttttcc tttgcaaaat
     2821 gacaaaaatc ataaactttt tgacaactat acttgtcaaa aagaaaaaga tgtgttacga
     2881 tgtaagcaag ttaagagaaa agaagaaagg agctatgatg tgggtactag gatttatact
     2941 atttatgatt ttcttttatt ctaataattc taaaaaaatc aagaaactag agaataaaat
     3001 caaaaaactt gagcgaaaag agaaaggaaa cgcagaaatg tcgagattat ttcaagaaat
     3061 gattggaaag gaaccaatta taacgggagt gtatattggg ccagataact gggaagttgt
     3121 ggatgttgat gaggaatggg taaagctacg acgtgtagat aatacgggaa aagaaaaatt
     3181 caagttgcaa cgcattgagg atatccaaac cgttgaattt gacggagagt aggtgtgtaa
     3241 catgcaactt aaaaatcgtc taaaagagct tagagctcgc gatggtctca atcaaaccga
     3301 cctagccaaa ctggcagggg tttccagaca gaccattagc ctactagaac gggatgagta
     3361 caccccatcc attatcattg ccctgaaaat atctcaaatt ttcaacgaaa cagtcgaatc
     3421 ggtatttcgt ttggaggagg acgagtgatg aacaagtata aagtgattta ttatgtagtg
     3481 gtcatagctt tattagtcag tgtatttcta ctgattggga tggacctaag ctggtttaat
     3541 ctctatcaaa gcgaccaatt tgtttgggtc tactttgctc tcatcccagt aattgaatgg
     3601 attgaaaaga aatccaaaaa tctagcaagt gaaaaaggag aatgaatatg aaaaagaaac
     3661 gtagattgtt atttttgatg tctattgtct tgggcatgtt tgtagggatg tttaaggcac
     3721 gtgtcgaatc ccacgaaatt attttagatg taaaagcctt gatgccatgg atatcagcta
     3781 tttgtttact gataggtttc attagtatgt ttttgacttt caatttctta aagaaaagca
     3841 gaaaatttca ttccttgtat caagaggaaa tggatgacga tctgaatgaa acctattatg
     3901 tgcaaatgta tcggaatctt gagtttggaa ccattgcttt taatattaca ggtgtagcga
     3961 ttccattggc tatttttatt tcattaagtg aggtgattat attgcataca aaccctcaaa
     4021 catttttcct ttctttctta ctctttgtgg tattcttagt cgctcaaaaa tctcttttta
     4081 aaaccattgc gattgttcgt cagtttgatt tggaattttt cgctacacca aaggatgtct
     4141 tgaactatat aaattcttat gatgaagggg agcgtcaggc taatttggaa cagagttttc
     4201 gaattttatt ccaattacac caatatgtct taccagcctt atatattttt cttattatca
     4261 tttctttctt gacaggagag attcagttac tagctttctt gcttgtagga gccatccatg
     4321 tttatatcaa tgtgatgcag ttacctatgg taaaacgtta tttcaaataa aggagttatc
     4381 tatgaaatta cttaaaaacc ttggctggat tcttctagcc cttctatcct ttttatttat
     4441 ctatggcttt attcaggggc tcgcgactgc gtcgcttgct ttaggcgctt caccctatgc
     4501 tgttactcta ctctatgtgg cctttgctgg agtatatgtg tacggcattt acaaatggta
     4561 tcagaaggct cctgttcata ttgagaagag cggctttaat cgatttattt ggcttcctgt
     4621 cttggtttgg ttcttatctc tggtcgttca attcttcttg ccagatgatc cttcagtaaa
     4681 tcagcaaata gcgacagact tgaccttgtc tcaaccactt ttctcattct ttgctgtggt
     4741 tatttttgct cctttgacgg aagagattgt ttttagaggg atgttagcac gctatctctt
     4801 tcctaagcag gacaatagta aacgaaccct gatttttctt ctggtatcta gtcttctatt
     4861 tgccttgatt cattttccag gtgatgtgca acaatttttt gtctatttta gccttggttt
     4921 tagtttgggt ttggcttaca ttagcagaaa aggtctggtc tacagtattt ctcttcacgc
     4981 tttgaataat ttagtcggct ttttgatgat tctcatgcta taatagagtc aggaggtcac
     5041 atgaaacgag taattttatt agcagtgatt caggcagtcg ttctattttt catcattgga
     5101 gcgctagctt atgccttcaa aggcgatttc ttctataact atctagcagt tgtctttgct
     5161 cctattgcag gtgtactgcg ttttgggacg gcttacataa cggaaattgt cttgcctcga
     5221 aaggcagccg aaatcgctga aaagcgtaaa gcaggcaaaa attcaaaata aaagagtccg
     5281 gtgaagttca tcggattttt gtattatact caatgaaaat caaagagcaa actaggaagc
     5341 tagccgcagg ttgctcaaaa cactgttttg aggttgtgga tgaaactgac aaagtcagct
     5401 caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa catggttttg
     5461 aggttgtaga tgaaactgac gaagtcagta accataccta cggtaaggcg acgctgacgt
     5521 ggtttgaaga gattttcgaa gagtattagc gctaattttt agggctttca cctgactttt
     5581 aaagactggc aaacttttct gatgattttc atgaagagcc tgcgctttta tggtaaaata
     5641 gtaacagaat aaaagaggag agaaataatg aaacgtagta tgtatgctgg tcgtgttcgt
     5701 gaggaacaca tcggacaaga aataaccttg aaaggatggg ttggccgtcg tcgtgacctt
     5761 ggtggtttga tctttatcga tcttcgtgac cgtgaaggaa tcatgcagtt ggttatcaac
     5821 cctgaaaaag tatctgcaga ggttatggca acagctgaaa gccttcgtag cgaatttgtt
     5881 attgaggtga ctggtcaggt cgctgcgcgt gagcaagcca atgataagtt gccaactggt
     5941 gcggttgagt taaacgtgac agctcttatt gtgcttaaca cagctaagac aacaccattt
     6001 gagattaagg atggcattga ggcaaatgac gatacacgtt tgcgttaccg ttaccttgac
     6061 cttcgtcgtc cagaaatgtt ggaaaatctt aaacttcgtg ccaaggtgac ccactctatc
     6121 cgcaactact tggatgagtt ggagtttatc gacgtggaga caccattcct ttctaagtca
     6181 acgcctgaag gggcgcgtga ttatttagtg ccgtctcgtg ttaataaggg gcatttttac
     6241 gctcttcctc aaagtccaca aatcacgaaa cagctcttga tgaatgctgg ttttgaccgt
     6301 tactaccaaa tcgttaaatg tttccgtgac gaggacttgc gtggagaccg ccagcctgaa
     6361 tttactcagg tcgacttgga aacgtccttc cttactgagc aagaaatcca agatattaca
     6421 gaaggcttga tcgcgcgcgt gatgaaggaa acaaaaggca tcgaagtaac gctaccgttc
     6481 cctcgtatga aatacgatga tgctatggct ctttacggtt ctgacaagcc agatactcgt
     6541 tttgacatgt tgcttcagga cttgacagaa gtggtcaaag gtgtagactt taaagtcttt
     6601 tcagaagcac ctgctgtaaa agcgattgtg gtcaaaggag ctgcggacaa ctattcacgt
     6661 aaagacatcg acaagatgac ggaagtagcc aaacagtatg gtgccaaagg tcttgcttgg
     6721 gtcaaggtgg ttgatggaga attaaacgga ccagttgcca agttcttgac tggtatccaa
     6781 gaagaattga caacagcgct tgctcttgaa gataaggact tggttctctt tgtggcggat
     6841 acgcttgaag tggctaatgc aacactgggt gcccttcgtg gacgtattgc taaagagctt
     6901 ggcttgattg ataatgataa gttcaacttc ctttgggtgg ttgactggcc gatgtttgaa
     6961 tggtctgaag aagaaggccg ctacatgagc gcccaccatc cattcacact tccacaggaa
     7021 gagactgctc acgaattaga aggtgatttg gctaaggttc gtgccattgc ttacgatatc
     7081 gtcttgaacg gttatgagct tggtggtggt agccttcgta tcaaccaaaa agaccttcaa
     7141 gaacgcatgt tcaaggctct tggtttctca actgaagaag ccaatgacca gtttggtttc
     7201 cttcttgaag ccatggacta tggtttccca ccacacggtg gtttggctat cgggcttgac
     7261 cgttttgtca tgttgcttgc tggagaagaa aatatccgtg aagtcattgc ctttcctaag
     7321 aacaacaagg caactgaccc aatgacacaa gctccatcaa cagtcgctct caaacaacta
     7381 gaggaactca gcttacaagt agaagaagat gaaacaaaca aaacgaatta agcggtggcg
     7441 ctattatctg cgccgctttg cttatcagat aaaaatttta cgtgtcttac aaagtatctc
     7501 tcgagaaaag tatgatgaga agatttcggc ctctctggtc tatggttttt tatcagcagt
     7561 agcagttaat ttctttttcc aaccagggca tgtgtattcg agtggtgcaa caggtctggc
     7621 acagattatc tctgccttga gtaatcactg gtttggtttt catattccga tttcgctaag
     7681 cttctacgcc attaacttcc ctttgatggt cttagcttgg tatcagattg gccataagtt
     7741 caccgtcttt acctttatca cggtatctat gagttccttc tttatccagt ttgtccctgt
     7801 ggcaaccttg acggaggatc ccattatcaa ttcccttttt gggggtgttg ttatgggttt
     7861 ggggattggt tttgctcttc gaaacaatat ctccagtggt gggacggata tcgtcagcct
     7921 gactattcgc aagaaaacgg gtaagaatgt cggtagtatt tctttcttgg taaatggaac
     7981 tatcatgctg atagcaggtt tgacctttgg ttggaaatac gctctttatt ctatgattac
     8041 catctttgtc tctagccgtg tgacagacgc agtctttact aagcaaaagc gtatgcaggc
     8101 catgattgtg acaaatcatc cagagaaggt aattgaaaaa atccataaaa aattgcaccg
     8161 cggagcaacc atgatccacg atgcagaagg aacctataat cacgagagaa aggcagtttt
     8221 aatcactgtc attacacgtg cagagtttaa tgaatttaaa cagattatga cacaagtgga
     8281 tccaagctcc tttgtctctg tctcggaaaa tgttcatatt ctaggaagat ttgttgagat
     8341 agataattag tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
     8401 cgtatatatg ttactgactt cgtcagttct atctgcaacc tcaaaaccat gttttgagct
     8461 gacttcgtca gttctatctg caacctcaaa accatgtttt gagctgactt cgtcagttct
     8521 atccacaacc tcaaaacagt gttttgagca acctgcggct agcttcctag tttgcacttt
     8581 gattttcatt gagtataaaa agatcttggg aaaagactca atttcagtag aaaaggaagt
     8641 aaatcttccc acaataaaac gcatagtatc aagttttttc aatacctgat agtatgcgtt
     8701 tttgctttta acgactcttt gcccagtctc ttatttttcg ataattttgt gggcgatcaa
     8761 ttgacggtaa caaatttgtt tattgttttt attatcatta ataatctgga gaatagtttc
     8821 aagggaaaca cgaccaagct ctaaactatt gatatcgaca taggctgcca agttgagctt
     8881 gggattaacc gagtcaaagc tgagaacagg gacatccagc tggtgtttgg caatatagtt
     8941 acaaacacct tcagctagga ggctatcggt tgtgatgata gcatcaattt gtggatcgtg
     9001 cttgaataat cgcttgctaa atttatagcc cttttcttcc agaaactcgt cggcaaagta
     9061 gatgcgattg ttgtcagtgg taagtttgta atgtttaagc gcctgttcat agcctgttaa
     9121 acggtctttg gtcacgaaga gctttttact tcctccgata aaggcaatgc gtttgcagcc
     9181 ttttttgatg aaatattcag tcgcatcaaa accagcttga acattgtcgt tgtcgacaag
     9241 tgggatgaaa ggagatagag atttacctag gataaggaag gggaactgtt cttctgcgac
     9301 gagttttacg agagggtctt cttcttgggc atagagaaag attagcccat ctacacgctt
     9361 gccgtagacc atttgtgaaa tagcgttgag acgctccttc tcatctttcc ctgttgctat
     9421 ctgaatggca tagtggtttt cagatgcgac ttgagagatg ccacgtagaa ccgatggaaa
     9481 gaaaggattc tggtagaagg cgtctgagtc atcaggaaga actaatccga taacctgagt
     9541 atagctgctt accaagctac gagcgttgag gtttgggtgg tagttgagtt ccttcatagc
     9601 cttgcgaacg cgtttttttg tttcgtcgct aatggttgat ttattttgaa taacacgggt
     9661 tacggttgaa ggcgaaacac cagcagcctt ggccacgtct ttaatcgtaa cgggcataaa
     9721 aatctcctat ttatggtaat ttggatcacg gaaatgtgtt ttataaaaga tagtgaccag
     9781 atacagaaca aaaagaatat tttgtacagt aatcagggtt gtcatatttt ggccaaataa
     9841 tcccaaaata agtgtaatca gagtcggcaa tcctaaacag ttcaagataa agtgatagca
     9901 ctctttaaag gttctaaatg aaaagaggcg tgatttctta gtgatataaa ggagaagact
     9961 agctcctaga gagacgataa agaaattcaa accaaagagg aagctcgcac cgagaactag
    10021 gaagaggctg atatagacac gattttgttg gtaccagtct ttagaaattg cttgggtcaa
    10081 gctgtctttg cttttgaaac tctcagtctg aatggctcgg taagagatgc gggtcagttc
    10141 cttgctttcc ttgctgatga ctagctcatt tgtatcgaaa tgcagttgca agttcttagg
    10201 taattccttg atttgacttg gaccaatcac aacagaagag gcttgactaa ctgttccagt
    10261 ataagttaat gtgccatcga caattgtagc atgttcagag agatcctgga caacctcatt
    10321 tgtcagaggt tcatagacat tatcgataaa agtttctagc ggataggtct cctgggagct
    10381 gttttggata gcaatgggta ccatagacaa gctgataagg aagatactgg taaagagaag
    10441 ttgaaaccag ttgagcccga aacgtttgga caggggctta cgaaacccca aaatacttga
    10501 aaaaaaggaa aatggatatg gaagcatagg tatctttcta aaaggtgttt tctatataag
    10561 tattattata tagagaaatg cgctttattt caagtctagg agaaaaattg cttgctacaa
    10621 ggatattatt tacagtgaca attgctaata atcaatgaaa atcaaagtgc aaactagcca
    10681 caggttgctc aaagcacaac tttgaggttg gagataaagc tgacgtggtt tgaagagatt
    10741 ttcgaagagt ataaaatgaa aaagggtggc ggggataaat tatcccttgt cgccaccact
    10801 tgtaagtcct gaaacaaagt tcttttgtag gaagaagaag agaatacaga ttggaagggc
    10861 gatgaggata gcacctgctg agaagtaggc aatcttcaag tttttcgcat tgttaacgaa
    10921 ggtttggaga cctacggcaa cagtaaagta ttctttctca cgaagcaaga aactagagag
    10981 gatgtagtcc ccgaaaggtc ccatgaaggc ccagagagct tgtacggcaa ccattgggcg
    11041 aacaagtgga agaacaattt gccagaagcg gcggaagtgt cctgcaccgt ctagttttgc
    11101 agattcgtct aaagacattg gcactgtatc gaagtagcct ttcatgagcc aagcattcat
    11161 cgggatacca ccaccaacgt agaggaagat gaggaaccag ttgtggttaa gggcgttcaa
    11221 cataagcgcc ataacgaaga aggctgtcaa agcggccata gttggcacca tttggatgat
    11281 caagaagaag accaaacttt gtttacgagc caagaagttg taacggctgt aagcataacc
    11341 agcaagtacg atgatacttg tttgaacagc catggtaatt aaggcgataa tcaaagtgtt
    11401 gaggtaccaa gtaccgtaca aggtttcagt gaagaggcct ttaaagttat caaaattgag
    11461 gtcgatatta gtatctagtt taaaggctga gacgttacct gctttaaagg ctgacataat
    11521 ggtaatcaac agtggataga taattacaat tgatagacca atcaggtaaa ggtaagtaag
    11581 gctttgagtc agtctacgtt tgagtttaat tgagttattc atcttagacg tcctccatat
    11641 caaatgcgtg tagtttcttg aatgcgatca tagagattga gatgacaatg atagagataa
    11701 tcaaggtaac agctgccgcc attgagtatt gaggagatgt acctgttgtc aaacggtaga
    11761 tccatgagat caagatatcg gttgaaccag ctccacctcc gacactacca ggtcctccac
    11821 cattgaagag gtacatgata gagaagttgt taaagttgaa ggtgtattgg ctaatcaaag
    11881 taggtgccgc aacagccaaa atcattggga aagtgatgtt gcggaatttt tgccaagcgt
    11941 tggcaccgtc aatataagct gcttcgtaaa ggtcgttagg aatagattgc aagataccca
    12001 aggtcagaac gtagatgtat gggaatccga gccaaccttg catcataatc aaggcaatct
    12061 tagtccaagt tgggtctgtt ttccaaggaa taagagctcc atcaaggaaa ggaaggaatt
    12121 tagccaagat tggcaatact tgagtgttga tagcaccgac actatcgtta aacatgtttg
    12181 agaatgtcaa gatagtgatg aaggctggga cagcccaagg aagaaggaaa ataacaccaa
    12241 agatacgttt tcctttgata aatggttggt tggcaatgat agctgtgaag ataccaatta
    12301 cgatttgtaa agtagaagct gccaaagccc aaatgatagt ccaagaaaga acagaaccaa
    12361 aggcagaacg gaaggtactc aagctccaaa tgtttgtaaa gttggtcaaa ccaacccagt
    12421 ccaacaactt gtttggtggc aagtgttgga agtcgtagtt ggtaaaggcg atcatcaagg
    12481 ttacgataac tgggaagata atcgcgaagg tcatggcaac ataagatgga atgatcaaga
    12541 ggtaagggaa gccattttca taaatccctt tgatcatgtc tttgagtgtg cgtggaactg
    12601 gaattccatt gttaatgcgt tttgcaatcg tatgtgcatc tttgatattt gagaaataaa
    12661 agagtacata aacgattaca aagattagat ggaaggcacc acgaatcagc ataaagaggg
    12721 aattatcacg acctggtttg tcaccaagag tgatgaggtt gctcaattca ggggttgcaa
    12781 gtgctaggaa gtaaaggaca aatacgatgg ttacaccaag gaagataaaa cctttggctt
    12841 tttgtttatt gtaaatctgt cctaacccag gaatgataga cagcagggct gctttactag
    12901 gttgttgctt ttccatatta actcctttca taggatacta cttttttata agaaagctaa
    12961 attatttgtg tctctattga taaattcaaa gggggatttg atttccaccc cccttgaaca
    13021 aattttttat tcaccaaatt tttgtttgat tgtttctttg atcaatgtta cagcatcgtt
    13081 agcagctgtt ttagcatctt tttgaccact tacagcatca aagagcatat ttttcgctgg
    13141 atcccaaact gcagacattt gagagatgtt tggcagtggt tgagtgttct tgaactgttt
    13201 gataacagct gttgtcaact catcgttttt accttcagcg tatgaacgag cctcagtatt
    13261 agctgggatt tcgttagtct tatcatataa tactttttgt tgttcagttg caacaaggaa
    13321 gtctacaaat ttttgagaag cttcaaggtt cttaacggct tgaggaatga cccaagcttt
    13381 accaccaccg aatgcagcat attcttttcc atttggaaga gttgggatag ttgcaactcc
    13441 gtagtttact ttagcatctt taaaggcttg agctttccaa ggtccgtcga tgatagcagc
    13501 tgttttacct tcttggaatt gagtttggat taagtttcca gcaccttctg tatcttgcat
    13561 acctttaggc catttttcgt accaagattt agcgtagttg atacctacga tagaaccgtc
    13621 gtttgcaaga ccgatgtctt tagcgtcttt accgttttgg ccaaagacgt aagcaccgtt
    13681 accggcaaga agtccatatg tatagtagaa gtttgtccag tcagctagga aggcagtagt
    13741 tttaccatct tcaccagcga atgcgtattt gctatcttta gcaaggtttt ccaagtcagc
    13801 aaatgttttt ggagcatctt tcaccaagtc tttgttgtag tacataacaa gtgactcgat
    13861 aacggcagga gcaccgtaaa ctttaccatt agcagctgtt acaagagatt tagttgtgtc
    13921 gtctgtttta gcaccatcgc tcaatttcac ttctgaaagt tgtccgtcag aaccaaggct
    13981 acctacacgg tcgtatggag ccatcataac atcagggaca ttaccagatt ggttgtcaag
    14041 agaaagttta tcaagacctc ctagagcatc accagtttta agagtgactt ttactccagc
    14101 ttctttttca taagctttag caacctcttc aatatagctc ttatatccct cgtctacata
    14161 tacagtgagt tctttgactt cagatgaacc agaatcagca ggcttatcag cagttttgct
    14221 tccgcaagct accaaaagca agctagcaag tgtaacagtt ccaagcaccg cagtgctctt
    14281 cataaattta gatgacatag tgtattcctc ccaaagaata gcaagtttta ttgataagga
    14341 aacgcaaacg ttttccttta tgagcttagt atagcacaaa tagaaaacgg ttgcaagtat
    14401 tttttgtaaa aattttaaaa aatttttaag cttgatttga tagcataatt ttgcatttta
    14461 atagaagaaa agtatgaaat agataagaat acagtatttt taataaaaat atatggaatc
    14521 tgtctaaaga gggaaaccag gaggggctac ctccctggtt ctaatcccta tctattttct
    14581 atggacgttt gtgctttgtt acatataaat tcaagctccc taaggaggtt ttgtactttg
    14641 tagactgtct cgtgagagtc aaaccttagg attagatagt tttaagttat ctttgctaaa
    14701 atgagttagt ctccttaaaa ataatcaaaa aagtttttta aaaacgcttg caattatgct
    14761 tgaaaaggag tatacttata agtaacgcaa acgtttgcgt ctgcaaaata cgcaacgttc
    14821 cattatttta acacacgagg tgctattatg aaaaaacgtc aaagtggtgt gttgatgcac
    14881 atctcttctc ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc ttacgacttc
    14941 gttgatttct tggtccgtac aaaacaacgt tactggcaaa tccttccatt aggagcaact
    15001 agttacgggg attctcctta ccaatctttc tcagccttcg caggaaacac tcattttatc
    15061 gatttagata tcttggtgga gcaaggtttg ttggaagcaa gtgaccttga aggagttgac
    15121 tttggtagcg atgcgtctga agttgactat gctaaaatct actatgcacg tcgtcctctt
    15181 ttagaaaaag cggtgaaacg tttctttgaa gtcggagatg ttaaagattt tgagaaattt
    15241 gctcaagaca accaatcatg gcttgagctc tttgctgagt atatggctat caaagagtat
    15301 tttgacaatc ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg taaagcttca
    15361 gcacttgaaa gctatcgtga gcaattggca gacaagttgg tttaccaccg tgtgactcaa
    15421 tacttcttct tccaacaatg gttgaaattg aaagcttacg ctaacgacaa ccacatcgaa
    15481 atcgttgggg acatgccaat ctacgtagcg gaagattcaa gtgatatgtg ggcaaatcca
    15541 catctcttca aaacagatgt caatggtaag gctacttgta tcgcaggatg cccaccagat
    15601 gagttttctg taactggtca gctttggggt aacccaatct atgactggga agcaatggac
    15661 aaagacggct acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat ctacgatatc
    15721 gttcgtatcg accacttccg tggcttcgaa tcttactggg aaatccctgc tggttccgat
    15781 acagcagcac ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc agccgttaag
    15841 gaagaacttg gtgagctaaa catcatcgca gaagaccttg gcttcatgac agatgaagtg
    15901 atcgaattgc gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt tgccttcaac
    15961 ccagaagacg aaagcattga tagcccacac ttggcacctg ctaactcagt tatgtacaca
    16021 ggaacacacg ataacaatac ggttcttggt tggtaccgta atgagattga tgatgcgact
    16081 cgtgagtaca tggctcgtta cacgaaccgt aaagaatacg aaacagtggt acacgctatg
    16141 cttcgtacag tattttcatc agttagcttt atggcaattg caactatgca agatttacta
    16201 gaattggatg aggcagctcg tatgaacttc ccatctaccc ttggtggaaa ctggtcttgg
    16261 cgtatgactg aagatcaatt gacaccagct gtcgaggaag gtttgcttga cttgacaaca
    16321 atttatcgcc gaattaatga aaatttggta gatttaaaga aataagacaa taatcaggag
    16381 acaactaaac atgttatcac tacaagaatt tgtacaaaat cgttacaata aaaccattgc
    16441 agaatgtagc aatgaagagc tttaccttgc tcttcttaac tacagcaagc ttgcaagcag
    16501 ccaaaaacca gtcaacactg gtaagaaaaa agtttactac atctcagctg agttcttgat
    16561 tggtaaactc ttgtcaaaca acttgattaa ccttggtctt tacgacgatg ttaaaaaaga
    16621 acttgcagct gcaggtaaag acttgatcga agttgaagaa gttgaattgg aaccatctct
    16681 tggtaatggt ggtttgggac gtttggctgc ctgctttatc gactcaattg ctactcttgg
    16741 tttgaatggt gacggtgttg gtcttaacta ccactttggt cttttccaac aagttcttaa
    16801 aaacaaccaa caagaaacaa ttccaaatgc atggttgaca gagcaaaact ggttggttcg
    16861 ctcaagccgt agctaccaag taccatttgc agactttact ttgacatcaa ctctttacga
    16921 tattgatgtt actggttatg aaacagcgac taaaaaccgc ttgcgtttgt ttgacttgga
    16981 ttcagttgat tcttctatta ttaaagatgg tatcaacttt gacaagacag atatcgctcg
    17041 caacttaact ctcttccttt acccagatga tagtgaccgt caaggtgaat tgctccgtat
    17101 cttccaacaa tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg aagcaatcga
    17161 aaaaggaagc aacttgcatg accttgctga ctacgcagtt gtccaaatca acgatactca
    17221 cccatcaatg gtgattcctg aattgattcg tcttttgact gcacgtggta tcgatcttga
    17281 cgaagcaatc tcaattgttc gtagcatgac tgcctacact aaccacacaa tccttgctga
    17341 agcgcttgaa aaatggcctc ttgaattctt gcaagaagtg gttcctcact tggtaccaat
    17401 catcgaagaa ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg ttcaaatcat
    17461 cgatgagagc ggacgtgttc acatggctca catggatatc cactacggat acagtgttaa
    17521 cggggttgca gcactccata ctgaaatctt gaaaaattct gagttgaaag ccttctacga
    17581 cctttaccca gaaaagttca acaacaaaac aaacggtatc actttccgtc gttggcttat
    17641 gcatgctaac ccaagattgt ctcactactt ggatgagatt cttggagatg gttggcacca
    17701 tgaagcagat gagcttgaaa aactgttgtc ttatgaagac aaagcagctg tcaaagaaaa
    17761 attggaaagc atcaaggctc acaacaaacg taaattggct cgtcacttga aagaacacca
    17821 aggtgtggaa atcaatccaa attctatctt tgatatccaa atcaaacgtc ttcacgagta
    17881 caaacgccaa caaatgaacg ctttgtacgt gatccacaaa taccttgaca tcaaagctgg
    17941 taacatccct gctcgtccaa tcacaatctt ctttggtggt aaagcagctc cagcctacac
    18001 aatcgctcaa gacattatcc atttaatcct ttgcatgtca gaagttattg ctaacgatcc
    18061 agcagtagct ccacacttgc aagtagttat ggttgaaaac tacaacgtta ctgcagcaag
    18121 tttccttatc ccagcatgtg atatctcaga acaaatttca cttgcttcta aagaagcttc
    18181 aggtactggt aacatgaaat tcatgttgaa cggagctttg acacttggta ctatggacgg
    18241 tgctaacgtg gaaatcgctg agttggttgg agaagaaaac atctacatct tcggtgaaga
    18301 ttcagaaact gttatcgacc tttacgcaaa agcagcttac aaatcaagcg aattctacgc
    18361 tcgtgaagct atcaaaccat tggttgactt catcgttagt gatgcagttc ttgcagctgg
    18421 aaacaaagag cgcttggaac gtctttacaa tgaattgatc aacaaagact ggttcatgac
    18481 tcttcttgac ttggaagact acatcaaagt caaagagcaa atgcttgctg actacgaaga
    18541 ccgtgacgca tggttggata aagtcatcgt taacatttct aaagcaggat tcttctcatc
    18601 tgaccgtaca atcgctcagt ataatgaaga catctggcac ttgaactaat actcttcgaa
    18661 aatctcttca aaccacgtca gctttatctg caacctcaaa gcggtgcttt gagcaacctg
    18721 cggctagctt cctagtttgc tctttgattt tcattgagta taagatacaa atttatacta
    18781 atacattttg taaaaaagcg agtttcgatt gaaattcgct tttttaaatg ctgtggattt
    18841 gggtcaatct tgtctaaaaa tagggaaatc ctagatacag tgaaggcttt aaatgctggt
    18901 ttttactgtc ttcagcctta tattttttcg tagttggtta cctcatatct cttgtattcg
    18961 cttacataaa gtattataat ataattgtag gaaagaaggt gtttttatga tatacacact
    19021 taaattggtg ttgtttatta cctttcttgt aataagcttg ttacctgata agatttttgg
    19081 aaaaaataaa aaaatttgga aaatagtttt tgcaatattg acggcagtgg cagcattgtc
    19141 atttatgtac taagttattt taagaatgta gggaaataaa ccctacattt ttttagtttt
    19201 ttctgttttc taaattctat ttatccaaga gcttcaacat ttcttgcttc ttcgcttcaa
    19261 gttctgcacg cttttcttcg atttcggcat gttttttctc gagttcagaa caacttgcat
    19321 cattgctaaa ttcttttcgc catcaggaga tagggtgagt ctacatgtct attactcacc
    19381 caaagcagtc ctacaaagca ggaattttct gttacttttt tggaaatagt aacgtttata
    19441 cagctttgac acttcgtatc aaagcgccaa acacactccg agggatttac agaaagcaga
    19501 aaaggaatga tctggtataa gatcattcct tttctctctt tttctttaag taattatata
    19561 caatgtacga cgaagtcgtc attgcaatgc tgatccacca cctaaaggga actttaaaca
    19621 acattgataa gataaagaat ataaacaacg aaaatacgtt atacccaatt aattttattg
    19681 tatatctcat gattaaaagt taatccttcc gttgttagga atggcatcat ttttatccca
    19741 taattgtgct aaataagtcc ccggtgataa taaattcata gcgaattcta aagcaacatc
    19801 atttacaaac caactaccta gatatctaga aattgctgaa cgaatagcac tttttgctgc
    19861 atgttttcct tttactttaa ttagatttgc aaggcctgca gtagttcctc ctaatgctaa
    19921 agctattgca gtatctaata gagcacccat ttgattaact gtaatacctt gccaagctgc
    19981 tctaaatgga gagtatgtag gtgggattgt ataatcgcct tgtaattgtc ggttaattac
    20041 ttctttgatc cattgttgtg agacgtctgg atgaaaagat tggatttcgt ttgcaagtgt
    20101 attgatttgt tcttctgtta gagaagtgac aggttgaagt tccatatttg tttcaatttg
    20161 tgatacttgt tcagaagcgt atacagctga aacacttgga atcgctgata caattaacac
    20221 aattgacgtc aaaaaaaccg aaataaattt cattaatttg ttcatgagct tttctccttt
    20281 ttatttgtat ctgcttacat tttatcatat actgttatta tagtcaaaaa aatatgctat
    20341 tatgttaaaa aaatattttt caaaatataa atggacggat ttattttgga ttttatttgt
    20401 tattttgacc tgcctctata ttggtaacca tgatttgttt actctcaatc atcaagaatt
    20461 ctcttttcgt ggtagcgttt ggggtctggt actggcctta tatcacttat tgttcattga
    20521 taagtttgta atttcgaatc gaaaataaag attagaacta tgattgactg gctactttta
    20581 atattgattt tggaggaaga ttttgtctct attatttatt attttaaatt tatctatttt
    20641 gtacaagatt tattctttga gacgggagaa atcgaaatac ttgatttata cggcctatat
    20701 catatttggg gtaaatgtag tatatggtat tcaatggtta ttaagagaac tgatttcaac
    20761 tatttcccct taatgtgtat ggaaactata acaaaacgca taagattaag gtttgtgtac
    20821 ctgttcttat gcgtttttat aatattgaag attttcggta agttttatac ctttgggaag
    20881 tctagtttag aatgctttcc caaccaaaat ctctgcttcg atggtaatct ctgtcagttg
    20941 gctccagtca atcttgctct ggtcaacgtg aaagaggaga ggagtcatac tgagtagggc
    21001 ttggagttgt tctgctgtga tagtcttagt cagagaggca gtttgactag ataggatggt
    21061 aaagtgttcc tggaaatgct ccttgatatc ttggttagaa tactccttgt ttgtcagctg
    21121 gtcctgtact ctttgacgga tttctttgag gtgattttca gttgggataa cctttatcaa
    21181 gataccgtct ttggataaaa cgcgacgaaa ttctccatag ttggcaggtg agaagatatc
    21241 aagcagaata tccatgttag cgtcttttat aggaagtcgt gccaagtcgc caacaaacca
    21301 attgactgcc cagttgggtt cacttttagc agcgatttgg actgaatctt tggagatgtc
    21361 aaaggcatag aaagtttttt cagagtgact ttcttgtagt ttgcgagaat agaatccttc
    21421 accacaaccg atatccaaaa ttgttgtggt agtttttgag cttgcaagca agtcagatac
    21481 agcatctaag atagcttggt aaaagccggc ttctaggatt tgttgacggt tttgaaaatt
    21541 ttccttgtta tagttagcag attgcttgat ttgaggtgct agattgacat agccaaattt
    21601 cgccaagtca aaagaatgac ggttgcagca cttgaaatta gtctctaaca gagtcagatt
    21661 ttcttgacag ataggacagg caaaggcagt cgcagaagca aaacgctgaa gtttgggctt
    21721 gagatttgta ttcatagttt aagtgtatca aaagaggcaa atgaaagcaa ctttaggaat
    21781 aagtagatgg gagattcagt agaaataaaa ctaattctcc aatttataga atgaaattgc
    21841 ttttatatct aaattgctat ataataatga taaggaggaa ataagtatgt taaaagaagt
    21901 attaaccgtt gcaaaagttg cgaaaaaatc ttcattattt ttgggtggtg tcgcatttgg
    21961 tacccttggt ttgaaaatct tagcaagtaa ggaagctaaa aaaggttatt ctaaagcttt
    22021 ggctaaggct tacaagttga aagacgagct agatgcatct gtttctgttg tgaagcaaca
    22081 tggagacgat gtcttgcaag atgccaaata tttgtacgag caagagaaaa aagaagagca
    22141 attagatagc cttataggtg aataatatgt cttttaaagt gctacataga ggataccaac
    22201 atatccgact atcatcttct ttttcactta ccttggatat tcaagactat cttcgttcct
    22261 tggcgagaga tgaaaagggg attgagtcta tccagtttta catggatcaa cagcacttta
    22321 ctctacgcat aaaagaaggc ttttctgtat tagataatgc agaagccttt ttaaaaagaa
    22381 ttgataaagg gaaagtttct gagttgatga ctcttcccat tcgtagagaa gagagtgctt
    22441 attctattgt ttcaggtgca gcggttaagc gtgtactttt tcgtagtttt gtgccgtatc
    22501 ctattcgcta tatatggact tgttatcagg ctttgggtta tattagagaa gcctatcaaa
    22561 cactagcgcg taaggaacta acgatggaag tcttggactg ttcggctatt ttattgtctt
    22621 tgtttatgaa ccaatccaag acagctagca atatcatgtt tatgcttgat ttggggaatc
    22681 atttagatca gtggtccttg aaaaaaactg caacagattt agaacagagt cttcttgcaa
    22741 aagagagcga tgtattccta gtacagggcg atacggttgt tagtatcaag agttccgatg
    22801 ttcaaatagg agatgtcttg atcttatctc aaggaaatga aattctgttt gatggacaag
    22861 tagtttcagg tttaggtatg gtcaacgaaa gttccttgac aggagagagt tttccagttg
    22921 aaaaaagaga gtctgatttg gtttgtgcaa atacagtatt agaaactgga gagttacgca
    22981 ttcgtgtaac agataatcag atgaacagcc gtattttaca gctgattgag ttgatgaaga
    23041 aatctgaaga aaacaagaaa acgaaacaac gctatttcat caagatggcg gataaagtcg
    23101 tcaaatataa tttcttgggg gctgggctga cttacctatt gacaggttct ttttctaagg
    23161 ctatttcttt cctattggtc gatttctcct gcgctttgaa aatctctact cctgtagctt
    23221 atttgacagt tatcaaggaa gggttgaacc gtgaaatggt gattaaggat ggagatgttc
    23281 tggagaaata tctggaagtt gatactttct tgtttgataa gacaggaaca atcacaacta
    23341 gttatcctat agttgaaaag gtgttacctt ttggagacta tagtgaggaa gatattctca
    23401 gaatcagtgc ctgtcttgag gaacacattt atcatcctat tgctaatgcc atcgtcaagc
    23461 aagctgagat agagggaatt gaacatgagg aaatgcatgg gaaactccaa tatatcgcaa
    23521 gcaaggggat caaatctcat atagatggcc aaccagttct tattgggaat tatgtcttga
    23581 tgcaggatga gcagattcat atcagttcag aacaaaatgc tttaattgaa gagtacaaga
    23641 gtcactacaa tctcttattc ttggcttatc aaaatgaatt gattggaatg ttctgcattc
    23701 atactccttt gagaaaagaa gcaaaaacag ccttggataa acttaaggca caggggaaaa
    23761 aattgattct ggcaacaggg gacaccttgg ttaggacaaa ggaattagtc aaagatttgc
    23821 cctttgatca ggtctataca gacttgaaac ctgatgggaa atttgagtta gtagagaaac
    23881 tgcagaaagc aggtcacact attttgatgg ttggagatgg attgaatgac tcagcggctt
    23941 taactctatc agatatcggt gtggtgatga atgagagtgc agatatttct aagcagatga
    24001 gtgatatctt attgttagat aatcgtttgg atttcttcca agagttggat tcgttatcat
    24061 catctttgca aacactcatc aagaaaaata ttcaagatac cgttgtcgta aatagtagtt
    24121 tgattggctt cggcttattt aattggctca gtccttcaaa tctctctatc ttacataatc
    24181 taacaacctt gcgcattgtc ctgcgtagcc tgtctattaa aaatagatag atgagagtta
    24241 ttaacagcaa aaaggagtta cctttctcga ggttaactcc tttgtttata gataaatgtt
    24301 gaatagttta gtaagtcaat acaaagtatt ttttcttccc acgacggata acagtcagtt
    24361 cattctctaa cttatcagcg tcactcaaga catagtcaag ctcttggatg cggtcgccgt
    24421 ttacgtagat ggctccgttt tggacgtctt cacgggcttg gcgttttgag ttaactatac
    24481 cagatgagac gagcagttcc acgatattgt tgttttcgtc tgcctgtact tggtagtttg
    24541 gcacaccacg aagtccttgt ttgagctctt tgacagaaag gtttttgatg tttcctgcaa
    24601 agagttgctc agtgatgtta agtgcttctt tgtaggcttc ttctccgtga acaagtgtaa
    24661 caacttcacg agccaagact ttttgagcca agcgttcgtg tggcgctgct tcaaattgtt
    24721 tacgaatatc ttcaatctca tcaagtgaca agaaagtaaa gattttcaag aagcgaacag
    24781 cgtcagcgtc catcacgttc atccagaatt ggtacatttc gtatggagaa gtcttttcgg
    24841 gattgagcca gacggcattt ccttctgatt taccaaattt cttaccagtt gcatctgtga
    24901 ttagtggaac agtgataacg tgaccagtct tgtccgcctt acgacgaagc aattcggtac
    24961 cagctgtcat atttccccac tggtcagaac caccgatttg aagagtgaca ttatggtctt
    25021 ggttaaggac gaagaagtca tacccttgca tgatttggta agcgaactca gtgtaagaaa
    25081 ttcctgtttc gatccgtttt ttaacagatt ccttactcat catgtagttg accgtgaagt
    25141 attttccaat atcacggagg aagtcaatga agctgatgct gccaaaccag tcgtagttgt
    25201 tgaccatgac agccttgttt tcgccatttt caaagtcaag aaaacgagaa agttgtcctt
    25261 ggatagactt gacccagcca tctactgtgt cttttgtttg gagactacgt tcagcatctt
    25321 tgaaggacgg atctccgatg agacctgtag caccgccaac gagcgcataa ggtttgtgac
    25381 ctgctagttg caagcgacga cttgtcaaga ttgcgacaag gtggcctagg tgaaggctgt
    25441 cagcagttgg atcgtagcca gtataataag aaacttgacc ttcttctagg gctttacgca
    25501 aagcttcttc atcagtcgtt tgaaatatca aaccacgctc ttttagctca tcaaaaatgt
    25561 gcatgtgttt tttctccttt ttaaaattat tgtttctacc tattgtatca caaacttggg
    25621 caatagccta gcagaatagg gaagaaagtg gctattttat tgaaaatttc ccttttgtgg
    25681 tataatagat aaagtgagga aatccatgca aaatcaatta aatgaattaa aacgaaaaat
    25741 gctggaattt ttccagcaaa aacaaaaaaa taaaaaatca gctagacctg gcaagaaagg
    25801 ttcaagtacc aaaaaatcta aaaccttaga taagtcagcc attttcccag ctattttact
    25861 gagtataaaa gccttattta acttactctt tgtactcggt tttctaggag gaatgttggg
    25921 agctgggatt gctttggggt acggagtggc cttatttgac aaggttcggg tgcctcagac
    25981 agaagaattg gtgaatcagg tcaaggacat ctcttctatt tcagagatta cctattcgga
    26041 cgggacggtg attgcttcca tagagagtga tttgttgcgc acttctatct catctgagca
    26101 aatttcggaa aatctgaaga aggctatcat tgcgacagaa gatgaacact ttaaagaaca
    26161 taagggtgta gtacccaagg cggtgattcg tgcgaccttg gggaaatttg taggtttggg
    26221 ttcctctagt gggggttcaa ccttgaccca gcaactaatt aaacagcagg tggttgggga
    26281 tgcgccgacc ttggctcgta aggcggcaga gattgtggat gctcttgcct tggaacgcgc
    26341 catgaataaa gatgagattt taacgaccta tctcaatgtg gctccctttg gccgaaataa
    26401 taagggacag aatattgcag gggctcggca agcagctgag ggaattttcg gtgtagatgc
    26461 cagtcagttg actgttcctc aagcagcatt tttagcagga cttccacaga gtcccattac
    26521 ttactctcct tatgaaaata ctggggagtt gaagagtgat gaagacctag aaattggctt
    26581 aagacgggct aaggcagttc tttacagtat gtatcgtaca ggtgcattaa gcaaagacga
    26641 gtattctcag tacaaggatt atgaccttaa acaggacttt ttaccatcgg gcacggttac
    26701 aggaatttca cgagactatt tatactttac aactttggca gaagctcaag aacgtatgta
    26761 tgactatcta gctcagagag acaatgtctc cgctaaggag ttgaaaaatg aggcaactca
    26821 gaagttttat cgagatttgg cagccaagga aattgaaaat ggtggttata agattactac
    26881 taccatagat cagaaaattc attctgccat gcaaagtgcg gttgctgatt atggctatct
    26941 tttagacgat ggaacaggtc gtgtagaagt agggaatgtc ttgatggaca accaaacagg
    27001 tgctattcta ggctttgtag gtggtcgtaa ttatcaagaa aatcaaaata atcatgcctt
    27061 tgataccaaa cgttcgccag cttctactac caagcccttg ctggcctacg gtattgctat
    27121 tgaccagggc ttgatgggaa gtgaaacgat tctatctaac tatccaacaa actttgctaa
    27181 tggcaatccg attatgtatg ctaatagcaa gggaacagga atgatgacct tgggagaagc
    27241 tctgaactat tcatggaata tccctgctta ctggacctat cgtatgctcc gtgaaaaggg
    27301 tgttgatgtc aagggttata tggaaaagat gggttacgag attcctgagt acggtattga
    27361 gagcttgcca atgggtggtg gtattgaagt cacagttgcc cagcatacca atggctatca
    27421 gaccttagct aataatggag tttatcatca gaagcatgtg atttcaaaga ttgaagcagc
    27481 agatggtaga gtggtgtatg agtatcagga taaaccggtt caagtctatt caaaagctac
    27541 tgcgacgatt atgcagggat tgctacgaga agttctatcc tctcgtgtga caacaacctt
    27601 caagtctaac ctgacttctt taaatcctac tctggctaat gcagattgga ttgggaagac
    27661 tggtacaacc aaccaagacg aaaatatgtg gctcatgctt tcgacaccta gattaaccct
    27721 aggtggctgg attgggcatg atgataatca ttcattgtca cgtagagcag gttattctaa
    27781 taactctaat tacatggctc atctggtaaa tgcgattcag caagcttccc caagcatttg
    27841 ggggaacgag cgctttgctt tagatcctag tgtagtgaaa tcggaagtct tgaaatcaac
    27901 aggtcaaaaa ccagggaagg tttctgttga aggaaaagag gtagaagtca caggttcgac
    27961 tgttaccagc tattgggcta ataagtcagg agcgccagcg acaagttatc gctttgctat
    28021 tggcggaagt gatgcggatt atcagaatgc ttggtctagt attgtgggga gtctaccaac
    28081 tccatccagc tccagcagtt caagtagtag ttctagcgat agcagtaact caagtactac
    28141 acgaccttct tcttcaaggg cgagacgata attctctaaa tgaagtggcc aatcaatgga
    28201 ttgccacttt tttcttttcg tgttacaata agggtatgaa tcagtatcag aaaaagattg
    28261 ttaacggaaa aatttattcg ctcctatccg gcttaatatg gggaatctgt ggaattttag
    28321 gagagtactt ctttactcat tatcaggtgt cttcgggctg gattacctct atgcgtttga
    28381 cactggcagg gagtcttgta ctcatttggt ctgcaataca attaaaatcg caagtgctag
    28441 atatttggcg agacaagaaa aattacctgc cctttttagc ctatgctatt ttggggattt
    28501 tttcagttca gtattttttc tatctctgtg tagaatactc aaatgctacg acagcaacta
    28561 ttttacagtt tattagccct gtctttatcc tcttttacaa tcgcttggtt tatcaaaaac
    28621 gagcgtcaaa aagcgctgtt ttctatgttt tggttgccat gctgggtgtt tgcttgatgg
    28681 cgacaaaggg agacctctct cagttatcca tgacgccgct agctcttata acaggtttgc
    28741 tgagtgccat gggtgttatg tttaatgtta tcttgcccca accttttgct aagcgttatg
    28801 gttttgttcc tacggttggg tgggggatga ttttggcagg tttgtttagc aatgtcctct
    28861 cgccggttta tcagctttcc tttactcttg atatttggag tatcttgatt tgcctcatta
    28921 tcgctttctt tggaacggct tttgcttttt tcatttccat gaaggctgtg tccttggttt
    28981 ctcctttggt ggttgccgtt atcagtgcca gtgaacctct ctcttctgct ctcttgagtg
    29041 ttttgttctt aggattagta gtggattggt ccctccttct agctatagcc ttgattattt
    29101 tacccatgat atttttgtct atagaagaag cgaaagaaag tagataaaaa gtcttttctt
    29161 aattctaaaa gtgtgctata ctagaatagt caataaaaca cggggagata gttgtgaaga
    29221 gtgtttttag gttgtatcgg taggggcttg cttttaccga cagcacgttt tatctcacat
    29281 ccctaaaaaa tcatacctaa aaacagacaa aaaggtttca aatttgaggc cttttttggt
    29341 agaataggta tcattataac gaaccaggag gcacctatga ctgctacaaa aatgaacgct
    29401 caagaaatta tccaatttat cgccaatgct gaaaagaaaa ccagtgtcaa agtaaccttt
    29461 gaggggcaac tcgcaactgc tgtgcctagc tctgttgtca aactaggaaa tgtcctattc
    29521 ggagactgga aggacgtggc tccgcttctt gaaggtttgg tagaaaatca agattatgtt
    29581 gtcgagcaag atgctcgtaa ttctgcagtt cctttgctag ataagcgtgc tatcaacgct
    29641 cgtatcgagc caggtgctat tatccgtgac caggtggaaa ttggtgacaa tgctgttatc
    29701 atgatgggag ctgttatcaa tatcggtgct gaaatcggtg ctggaaccat gattgacatg
    29761 ggtgccatcc ttggtggccg tgccatcgtt ggaaaaaata gccacgttgg tgcaggtgca
    29821 gttttggcag gtgtgattga gccagctagt gctgaaccag tccgtgtcgg agacaatgtt
    29881 ctcatcgggg ctaatgcagt ggttatcgaa ggagtccaaa tcggtagtgg ttcagttgtc
    29941 gcagcaggag ctattgttac ccaagatgtc ccagaaaacg tggtagtagc aggtgttcca
    30001 gctcgtatta tcaaagaaat tgatgcccaa actcaacaaa aaacagcgct agaggatgcg
    30061 cttcgtacct tgtaattgta aaagtaaaaa agaggcggaa ccctttttcc agcctctttc
    30121 tgctatatcg gaggacagat agatgttaga tttgattcag actagacgag atttacacca
    30181 gattccagag attggcttgg aggagttcaa gactcaggct tatttgctgg atgtgattga
    30241 gaaattgact acgggcaagg attttgttca aattcgtact tggcggacag ggattttggt
    30301 ctacctgcag ggaagtcagc cggagcgaac cattggttgg cggacagata ttgatggcct
    30361 gcctatcgtc gaacaaacag gtctaccttt tgcttctcaa caccaaggtc gcatgcatgc
    30421 ctgtggccat gattttcata tgaccattgc cttaggctgt cttgagcgcg cccttgagga
    30481 gcaacccaag aataatctgc tctttctatt tcagcctgct gaagaaaatg aagctggtgg
    30541 tatgctcatg tatgaggacg atgcttttgg agattggttg ccagatcaat tttatggcct
    30601 ccatgtccgt ccagatttga aagtcggcca gattgcgact aatactcata cactctttgc
    30661 aggaacttgc gaggtgaaga tccgtttcaa aggcaaaggt ggccacgcag cttttcctca
    30721 tgaagccaat gacgccttgg tggcggctag ttactttgtg acccaagtgc agtcagttgt
    30781 tagccgcaat gtcaacccaa tcgagggagc agtggtgacc ttcggcgttt ttcaagctgg
    30841 aaccaccaac aatgtcatca cagacacagc ttttttacat ggaactattc gtgccttgac
    30901 acaggacatg agtctcttgg tgcaaaagag ggtaaaaaca gttgcagaag gggttgcagc
    30961 tgcctttgat atggaagtcg aagtggaact caaacaaggt ggatacctac ctgttgagaa
    31021 caatccagcc ttggcgcgtg aactgatgga cttctttgac gaaaaagacg gaatcgagtt
    31081 gattgatatc gaacctgcta tgacaggcga ggactttggt tatctccttt caaaggttga
    31141 tggcgtgatg ttttggctag gtatcgatag tccctacgct cttcatcacc ctcaaatgag
    31201 tcctaaggaa gaagtcttag ctattggggt ggctgcggtg tctagtttcc tgaaaaagaa
    31261 ggcagcagaa tagagggctt gtctatgaaa tcggaattac gcaagcaagt cttgcatgaa
    31321 atgaaggcta tatctcaaga gcaaaaacag gctatagacc aagctttaac cgagcgaatt
    31381 ttacaacacc ccttttatca agaagccaag gtcatcgcaa cctacctctc tttttctcat
    31441 gagtttcaaa cgcgggaact gattgagcag gcgctgaagg acggcaagaa ggttttaata
    31501 cccaaaactt atcccaaggg gcgcatggac tttgtagtct atgatccgca gcagttggta
    31561 aaaactgcct ttgccttact ggagccacag ggagatttgg aagtggtgga tgcatctcag
    31621 attgatttga ttcatgttcc tggcctggct tttacgacgg atggatatcg gattggatat
    31681 ggtggaggtt attatgaccg ctatctggaa catttttctg gtcatacttt gagtacggtt
    31741 catccttgtc aaattcagga ctttatacct gaaaaccatg atattcctgt tcaggaggta
    31801 ttaattgatg aaggaaatct ttgatagacg ttaccctgtg acgagtttct tcctcttagt
    31861 gacggccttg gtatttttac taatgttggt cactgcaggc ggaaactttg acagggcaga
    31921 tacattattt cgatttggag ccatgtatgg gccagctatt cgcctctttc ccgagcaggt
    31981 ttggcgtctc ttgtctgcca tttttgttca tattgggtgg gaacatttca ttgttaatat
    32041 gctttcactt tattatcttg gaaggcaggt agaggagatt ttcggttcta agcagttttt
    32101 ctttctctat cttttatcag gaatgatggg caatctcttt gtttttgtat ttagtcctaa
    32161 atccttagca gcaggcgcct ctacctctct ttatgggcta tttgccgcga ttattgttct
    32221 tcgctatgca actcgcaatc cttatatcca acagctaggg caatcctatc tgacactttt
    32281 tgtggttaac attattggaa gtgttctgat tccaggaatc agcctagcag gccatatcgg
    32341 tggtgcagtt ggtggcgcat ttctagcagt tatctttcca gttagaggag aaaaacggat
    32401 gtataacacc agccagagat taggagcggt agtcttgttc gtaggactcg ccattttgct
    32461 tttctacaag ggaatgggaa tgtgacgaag ttgaaagaaa atttgtgtaa tgaaaaaaga
    32521 taaggcattt tttgaacctt atctttttat tttattttat tccttctcag tcaattcttt
    32581 tccaagttgg atgaggtaat tcttcaaatc atctttgact tgtgggtgtt tgagggcgta
    32641 gtcgatggat gttttcatga agccaaactt gtctccgaca tcgtaacgag ccccattgaa
    32701 ctcacgagca aatacacgtt gtgttttatt gagggtgtcg attgcatctg tcagctgaat
    32761 ttcatttcct gcacctggag cttggttttc gaggatttgg aaaatttcag gcgtgaggag
    32821 gtagcgtccg ataatagcaa ggtcgctagg agcgtcctct ggagctggtt tttcaacaaa
    32881 ggtttcaaca ctgtaaagac catcttttcc ttcgccttgc ggagcaataa ccccgtaagc
    32941 agatacttcg tcatgaggga ctggcatgac agcgatagta gacgcgtggg tacgctcgta
    33001 gtcatccatg agttgtttgg taagtggaac agccttttcg tctgtgatat ccatcaagtc
    33061 atcaccaagc ataacgacaa aaggttcatt tccgacgaaa gccttggctt gcaaaacagc
    33121 atctccgaga ccgcgtggat gagtttggcg gataaaatgc agccgcatgt cagttgtttt
    33181 atcaactagc ttcaaaagat ctgttttccc tttttctttg aggttatatt ccaattcgaa
    33241 gtttgaatcg aagtggtcct caatagaacg ttttgattta ccagtgacaa ctagaatatc
    33301 ttcaatacct gatttgagag cctcttccac gataaactgg atagttggtt tgtctacgat
    33361 tggcaacatt tctttggcaa gggccttggt tgctggtaaa aatcgagttc ctagtccagc
    33421 agcagggata actgcctttc taacttttga tgtcataaaa atcctttcta tagagggtta
    33481 agaccactca ttttctgctt taaattcatt gttcatgatg tcataaatgg catctttgat
    33541 attggttccg tgataaataa cttggtaaat agcctgtgta atgggcatat agactccaag
    33601 ttcttgggct agttcatagg ctgctcgagt cgttgaaatt ccttcgatta ccatgcccat
    33661 attagcttct atatcagcta gggattctcc tcgtccgaga gcatctccag ctctccagtt
    33721 acgagagtgg atggaagttc ccgttacgat caaatctccc acaccagata agccgctata
    33781 ggtcaatgga ctggccccga gtgctacccc taggcgggtg atttctgcta aacctcgagc
    33841 gatgatggct gccttagcat tatcaccaaa tccaagacca tgtaaagctc cagcaccgac
    33901 agcaataata tttttaagag caccagcagt ttcaaccccg ataacatccg tattggtata
    33961 aagtcggaag tagtgattac taaatagctc ctgaacgtat tgagctgttt gtaaatcttt
    34021 agaagcagca gttattaaag ttaggtcacg cacaatggtc tcttctgcat gactaggccc
    34081 tgaaacaacg acgatatcac tacggagatg ttcaggaatt tcttcttcaa gaatggttga
    34141 taatcgttta tggctatcag gttctaatcc ctttgatgcg tgcatgatga taaccttatg
    34201 gtccaaggtt tgtgcaactt gctgggcaac aagtcgtgtc acttttgttg ggacaacaaa
    34261 caaaatcgca tccacatttt tcaatgtttc tgctaagtcg gtgtaggcaa tgatattttc
    34321 gtctagaacg acatctttaa agtagtgctt attagtatgg tgtgtattaa tttcattgat
    34381 ttgctcggga agatttcccc aaatacgtac ctcgtgtcca ttgtcattta agacttgtga
    34441 aagggcggtt ccccaagaac caggccccaa gacggcgacg gtttgttttt ccatgatttc
    34501 ctccttgata gatttctttc tcttattcta tcatattcta ggggattttg cacttgcatt
    34561 actggggtat ggtggaaaaa tacacaaaga ccgagatgaa gggataaact cttagtcttt
    34621 agttaaagtg agaagaaatc tgatagatag tttgattcag tatatgctta taatagaggt
    34681 aaacaactca ggaagttctt gtaggttgcg agagtttggc gaaaaaatta aaagattacg
    34741 tttggctaaa aaaatcagtc gttcagaatt ttgtggtgat gagtctgaat taagtatccg
    34801 tcaattaatt agaattgaaa atggagaatc cagaccaaca ctaacaaagt taaaatatat
    34861 tgctgaacgt ttggaggttg aagattacaa gttgatgcca agttatatag agttggataa
    34921 ggaataccta gaattgaagt atttcttgat gaggactcct acatacgaag atgaaactat
    34981 cgcccaaaag aaagagagtg tttttgataa gatttttgaa gagtattatg ataggctacc
    35041 tgaggaagaa agatttatca tcccaaatta ttcatatcta gcactagcga actacacagt
    35101 tcaaaaatta ccagaaaagc tagttgaaat actgtccttc tggtgatttt gcttaatttc
    35161 tgatgttcga gacatgattg aggagatttg tcttgatttt ttcctaaaaa agggcagact
    35221 cctcccttgg tttgatgctc gatttttaaa ataaggtgac ttattctgtt aggcagtttt
    35281 cccctgccct ctagctctat atggaacagg gagtatcaga tttatctggc agattgtatc
    35341 aaataaggct tgaaactgtt ttgaataggc gtatagactt gagaatttga gaatatgtcg
    35401 tctagcagta gagacatatt ttccggcaat atgaaggaag agacgtcgaa aacgcttgat
    35461 agtcaaggcc tttacttcat caccagctag ctgctttaaa aagaggtaga gattataagc
    35521 cagacagccc atcatcatac gtacttcatt cttaatcatg gtcgaactat ctgtcttatc
    35581 cccaaagaat cctgctttcc tttctttgat aaagttttca gcattccctc gttcacgata
    35641 gaattgaaac agctcctcac tatctacact gcttaaattg gtcaaatgaa cttttttaca
    35701 accataaaaa agagcactta atcgtactct tctcttttaa ggattagttg aattaattca
    35761 aatccactag ttctcctgtt tctaggtaga ctaggcgttc acaaatgtta gcaatgtaat
    35821 cagcgaagcg ttccagatgc cctatgatat aaaggtattg agttccattg ggaattgagg
    35881 tttcttggtc tttcataagt ccaatgattt cctttgataa ggcataataa tattggtcaa
    35941 tctgttcatc tttttgagca atactaatag cttttgaggc ttggtgcaaa ggaaaggcaa
    36001 ccaataaatc ggctagcatg ctgagggata atttacccat ttggtgtaac tgttcttcgt
    36061 caggggctag ttgattttct tttagttgca aaacagcttt ggcaatgcct gccatatggt
    36121 ctcccatacg ttcaaggtct gaacaagaag acatgatgct aatcacaaat cgaaggtcag
    36181 acacttgtgg ctgctgcaag gccaacaaac gggcacaggt caattcgata gcgctttgac
    36241 cttggtttat agcatgatcc ttattgataa ttagctctgc catctccttg tctttggagg
    36301 ctaaggccag taaggctttt gaagctgttt caaggacaag ttgccctagt cctaaaaagg
    36361 attgttctaa ttcatgcaat tctaagtcaa attgatttct cataggtttt tccttcctta
    36421 tccgaaccgt cctgaaatat agtcttctgt gcgctgatct tttggattgg taaacacgtc
    36481 aacggtatct ccaaattcgc aaatttctcc tgttaagaaa aaagcagttt tatctgaaat
    36541 acgtgaagct tgttgcatgt tatgggtaac aatgataatc gtataatcct tttttagttg
    36601 ctgaatgagg tcttcaattt ttaaagtgga gatagggtct aaggctgaag tcggctcatc
    36661 cattaacaga atatcaggtt ctactgctaa agctcgcgca atgcaaaggc gttgctgctg
    36721 accgccagat aaggacatgg cactcttttt aagatcatct ttgacttctt cccaaatggc
    36781 tgcccctttt aaagatttct ccactaaggc atctaattgt tttttgtctc gaataccatg
    36841 tgtccttggg ccataagcca cgttatcata gatagacatg gcaaagggat taggctgttg
    36901 aaaaaccatc cctacacgct tacgtagctg attaaggttg aatttgctac tataaatatc
    36961 ttgctcatct aagaggactt ggccttcaat atggcaagaa ggaaccaaat cgttcatccg
    37021 gttaagggtt tttagaaaag ttgatttgcc acaaccagat gggcctatca aggcagtaat
    37081 ctgtctttct ggtaattgaa tcgaaatatt ttttaaggct tgaaaatccc cgtaaaataa
    37141 gtctaggtgt ctgactgaaa atgttcccat actaggaagc tcctttcaca agttttcgag
    37201 ataataagct tgatagagta tttatcatta aaacagtaat aatcaaaatc acaccggtag
    37261 cataggcttc attgacatgt agcccctcac ttgacagcat atacatatgc agggctagag
    37321 aacgacctga agacatgaga ctacttggcg tattggtaga ggtacctaat gtatacatga
    37381 gggcagctgt ctcaccaacg atacggccaa tagctagtat cactccagct aaaatacctg
    37441 gcatggcaac tggtagaaca attctaaaaa cagtccgtaa cttacctgcc ccaagtccat
    37501 aacttgcttg acgcatgcta tcactaacag ataaaagggc ttcttctgtt gagcgaataa
    37561 tgactggcaa caccatgatg actgaggtta agattcctga taacagagag tattgaaaac
    37621 ctaagaagac tacaaagaag agcatgccaa acagaccaaa aacaatggaa ggaatcccag
    37681 acaaggtatc tgaggccaat cgcatgattt taacacaaag ggaatctttt tttgtatatt
    37741 ccacaagata aaaaccagca aaaatcccta tgggcaaggc taaaagaaga gcaccaaaga
    37801 ccagaataac ggtggaaata atcgctggca taagggaaat gttctcagaa gtataagtcc
    37861 aagaaaagag ggatagactt agatgaggta aacctttgat gaggataaaa ccaatgatta
    37921 aaaagagaga gccaaaggtt aaagctgaaa aacaataaac gagaagtttt agcaggtatt
    37981 tactcataag atgattttcc tttcaagtag gcaaagtagg cattaatcaa gagaataagg
    38041 aaaaagagaa ctgctgaggt tgcaataagg gcttccctat gctgacctga tgcgtaagcc
    38101 atttccagaa caatattggt tgttaaggtt ctggttcctg aaaagagtcc acttggaata
    38161 atcggctggt tgcctgccac caaaataact gccatggttt cacctactgc gcgaccgatg
    38221 cctaaaataa ctgctgataa aataccagat ctcgcagctg gcaagatgac actaaaaata
    38281 ctccgttcat gactagctcc tagagccaag ctaccagaat aatacgtttt gggaactgtt
    38341 cggatagcag attctgacaa actgataatg gttggcaaaa tcattattcc taatagtaac
    38401 gaagcggtta ggacactcat gccatttcct aaaaagcttc taatccaagg caccaataat
    38461 tgtaggccga aaaaaccata aacaatagat ggaatggccg ccatcaagtt gatagctgat
    38521 tttaagaagc catagacggg ctttggacaa taataaacca taaacaccga tgtcaagatg
    38581 cctgttggca ccccaatcac aatcgctcct aaggtaatta ataaggaacc aacgatcatt
    38641 ggtaaaatac catagcttgc cggaatgttc gttggcgacc aatcactgcc taataaaaaa
    38701 cgggcaaagc cgtagttagc catgaaaggt aagccattac taaaaataaa gaaacagatt
    38761 agcaaaatag ctacaacagc tactgttgca ctcatgaaaa aaattgccct aaaaactgct
    38821 tctttgaagg cttgttttat cacatcttgt cctttctagt gaagaaagta agggagatac
    38881 gacacctccc tacttgcctt ctttatctta ttgtacgatg aaacgtctgc atctctttag
    38941 agatttatgg agcaaacatt ttatttaatc ttgtcccagg tggttaattt gccactaaaa
    39001 acgtctgcaa gttcagccat actgacttgg cttgccttat tgtcattatt gaccacaaca
    39061 gcaataccgt ctaaagcaat agcatcatgg gtgagactct taccttcttc aggagttaat
    39121 tccctagaaa ccataccaat atcagcggtt ttctccttaa cagcggtaat acctgctgaa
    39181 gacccattag aggtaatatc aatcgtaact tctggatttt cttttttata agcttctgct
    39241 aatttttcca ttaaagaaga tactgaagtg gaacctacaa cagacaactt gcctgataag
    39301 tgttggcttg tatattctgt ggtttcagtt ttagcttcaa taaatttatt atctgtgacc
    39361 acttgttgac cttgtttgga gtggataaag ctgataaaat cttgacctag cttggaaaga
    39421 ttagaagacc aaacaatgtt gaagggacgt tgaagagggt attcaccatc taaaactgtg
    39481 tctcgactag ccttgacacc atcaatctct aaagccttga cagatttcgt taaagatccc
    39541 aaggagatgt agccgatagc attagcattc ccttgaactg ctgagagaac accttctgta
    39601 ctattttgaa tcacagctgt tttggcagtg ttgtcaattt ttttatcacc gtcttttttg
    39661 agaatccctg tgatttctgt gaaggcaccc cgtgttccag agccattttc tcgtgaaatc
    39721 acctcaatcg ttcctgaagc tgactgtttg gaagcagctg actgattgcc acaggcaaca
    39781 agcccaaatc ctgataagcc aatggctgca agagtaagca tttttttgaa tttcataata
    39841 atcaccttta tctctatgta tttttcttgt gtaggcttac tacatttata gtctaacaag
    39901 tctttgtaaa ggtttatccc tgattcatgt aaagattgtg taaagaatca aaaaaagcca
    39961 cttttgaaaa atggctgctc ctaaaaatag ctttaaaaat tattagtcct gtgcgaaaga
    40021 ttggttagga agaaaaatcg tgaagcaact gcctctgcca agctgactcg tcaccgtgac
    40081 ttggccacct aataattgac tgagttcttt gacaatggca aggccaagac cagtgccacc
    40141 agtttgtctg cttcgacctt tattaactcg gtaaaaacgt tcaaaaatac gatcctgctc
    40201 taattgacta ataccaatcc ctgtatctga tacagaaatc ttaatgcctt cgttcacctt
    40261 ttgggtcttg acctcaattt ttcccccttg ttcagtgtaa cggatggcat tggataaaag
    40321 attgagtaag atttgggaaa gtaattgact atctgatacg agggtgacat catctggcac
    40381 ctgcaccttt agctgtaaat ccttcttctt gagctgaggt tgcaagcttt gagtcaaatc
    40441 ctgtacaaat tcagccaaag aaagggtcgt ccattgtata ggcatttgtt gagccttaga
    40501 taaggtaaga agatgctcaa caatatgctc aagacgcaaa ctttctttgt aaataatgtc
    40561 tagaaagtca tccttgagcg cttcttcttc agctgacatc cccttaatgg tttcagcaaa
    40621 gcccttaatt gaagtaactg gtgtcctcaa ttcatgggag gcatttgaga caaaggctaa
    40681 atttaacttt tcataagttc taatcgttgt taaatcatat agcaagacga gcacagcttc
    40741 cacagattgg gtggggctaa aaacgggaac tgctgtcact tctaaaatca agtcaccctc
    40801 atgaaaccca cttacttctt gttttaacct tgttttttga tcaaaggctt ggtgaactaa
    40861 attccgaata tccatccgtt tgaggtcatc aagtgaactt atgtcgccgt ccacatcggg
    40921 aaaataatga ggcagagagc gactggataa taacatctga ccttgagcgg aaactaaaaa
    40981 cgtccccatg gttaggtgcg acagaagaac ctccattgtt tcggctaggt ccttgtattg
    41041 ctgatcctgt tgggagactt tggtttttag gccagacaca tactgagcca aagactttaa
    41101 gtcttcttgc cctttttcta aaaagtattc actactggtc aagagaggtt ggtgcaaggt
    41161 ctcaaaagca acttcccatt tccaaaggca aaagagccag tagccacctt gtcccaaaga
    41221 aagggctaga agaaagagac cgatgccttt actgatccaa gttaatgcca tccctgcaat
    41281 cagaatgagg ctaacactta gattgactag ccaaaattga aggtagcgtt tcatctataa
    41341 ctccttgaac ttataaccat aaccccgaat ggttcgaata aattgagggg ctttaggatt
    41401 gtcttcaatt ttttccctca acttaccaat atgaacgtcc accaaacgtg tttcctgccc
    41461 aaagtcatac ccccagatac gttccaaaag acgctctcta gtcagtgtca tgttgggatg
    41521 tttcataaga tagagcaaga gttcaaattc ttttggggtc aaactcagta acttattcgc
    41581 cttgtagact tcatgacgct cagggtatac tttcaaggtc ccaaatagcc aagaatcgtc
    41641 agcgatatta tctgaatcat ctccttcttg ttctccttta gttcgcctga ggacagcctt
    41701 gacacgcgcc agcaattctc tagggctaaa aggcttggtc aggtagtcat cagcccctaa
    41761 ttccaaggcc aaaaccttat caaattcatc acttttcgca gaaaccatca taattggagt
    41821 tttgacgcct ttggctctca gccgcttaca aacttccatg ccatctaatt gtggtaacat
    41881 gatatcaagc aagataaaat caaagggttc tgtttctgcc aaagctaagg ccttccgtcc
    41941 atttgttacc aattgagtag aaaagccttc cttacttaaa tggtagtcaa gcaatttcag
    42001 aatgtgttct tcatcatcca ctaataagac ttgttttgtc atctattatc tcctattggt
    42061 aacattataa cacaattatc agaaatccta acattgctaa atcagattaa atttgcttat
    42121 caagactagt atctggtcaa acgctcaatc atctccttgt gctctggata ggtcgccagt
    42181 agatctaccc tttcaaataa ttcaaaatcc tcaaattcaa aaccaggagc aacaagacaa
    42241 gaaaccagag cataatcctt atcaactgtt gatccccaaa tagtgccctt aggaacacag
    42301 tagtgaagtt gttgcccttt ggatatgtcc aggcctaaag tgactgcttc gtagtgacca
    42361 tctgctgtaa tcatgtgaac agtaagtggg gatcctgcat gaaaatacca gatttcatct
    42421 gctgtcaatc ggtgaaaatg tgaaggattc gtttcttcta ataagaaata aatactggta
    42481 taaagcgccc ttcccttacc agcaaggttt atagtgtctg aagctttttt tgtttgtcta
    42541 aaatagccac cttcaacatg gggagctaac tctagagttc ttatcaagtc ttctttatcc
    42601 atcggggcca atgggttgaa gtaactcttg ttcaaagtgg ttttacgatt tcaagaactc
    42661 ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtacaaatc aatcgcccta
    42721 aaaaaagaat tagcgaatga ttctggtaaa aagaaatttc acgctatgaa ggctcaagcg
    42781 attgtcacaa gtcaagggag aattgtttct attgccatga tatgaagttg ttcaaaatga
    42841 gttgcagaaa tatcggacaa gctggtaaaa tcttggctga cagtgattat caagggctca
    42901 tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag ccgctaacag
    42961 ctgaagataa agcctataac catgcgctat ctaaggaaag aagcaaggtt gagaacatct
    43021 ttgccaaagt aaaaacgttt aaaatatttt caacaaccta tcgaaatcat cgtaaacgct
    43081 tcggattacg aatgaatttg attgctggta ttatcaatca tgaactagga ttctagtttt
    43141 gcaggaagtc tattatttgg ttaggtgaat tagtgaagtg tttaggcaag tgtctctggt
    43201 tacgacgtca tggcctctaa atcgattata tttaggggtc atgactagtg aagcagttag
    43261 ctagttcgca tataagcggc tagcgtctaa caattaggaa ctttagttcc aataacttta
    43321 agattacgac gttttaggac ataaatcgat catatttatg tcctaaaact agtgaagcgc
    43381 ctagccaaag tccgaatagg atttggcgtt agttacttag attgctttgc aatcaagtaa
    43441 ctttggcgat ttacatcttc tctggcgctt ctactccaag caagcgaagg gcttctttga
    43501 gaacgactgc ggttgcgtag ctgagggcta gacggctgtc gcgttctggg ctttcatcca
    43561 agatacgtgt atgtgcatag tatttgttaa aggattgagc caggctaatt gcaaatttag
    43621 caatgataga aggttcaaag ttatctgccg cacggttgat aatacgtggg aagtcttgaa
    43681 tgagtttaat gatttcccag ctttcagtat cattcaagct atagttgcca gctgtttctg
    43741 gtttgaaatc ggctttgcgt aagatagatt ggatacgagc gtaggcatat tgaacgtaag
    43801 gtccagtttc accctcgaag gataccatag cttctaggtc gaagtcgtat ccatttgtac
    43861 ggtcagtttt gaggtcatag aatttaatgg ctccaacccc aacagcatgt gctacttggt
    43921 ctttgttttc tagttcagga tttttagcct cgatttggac cttggcacgg ctaacagcct
    43981 ctgcaacagt aggctctagc aagatgacat tccctttacg agtagagagc ttcttccctt
    44041 cttttgtaac cagaccaaaa ggaacgtggg taatgtcgtc actccaatcg tagcccatct
    44101 cttgcaagac agctttgagt tgtttaaagt gggcagattg ctcttgacca acgacgtaga
    44161 tagatttagc aaattggtat tcatttttac ggtagagggc tgcagccaag tcacgtgtga
    44221 tatagagagt tgcaccatca gacttcttga tgagggctgg atgttcaatt ccatatttct
    44281 caagattcac aacttgggca ccttctgatt caagaagtag tcctttttca gaaagaatgt
    44341 ctacaactgc atccatctta tcattgtaga aggcttctcc gttatagctg tcaaattcaa
    44401 ccttcaattc attgtaaagg cggttaaatt ccactaaact ttcatcgcgg aaccattgcc
    44461 aaagagcgag agcttcctca tctccatttt caagtttacg gaaccattcg cgcgcttctt
    44521 catccaagct agggtcattt tcagcttcag cgttgatgcg gacatagagt ttaaggagtt
    44581 catcgattgg atgagctttt acagcttctt cgtcgcccca ttttttgtag gcaacaatca
    44641 acatcccaaa ttgtttaccc cagtctccca aatggttgac cttgaccgtt tgataaccga
    44701 ttttttggaa aatatgtgac aagctatctc cgataacagt tgaacgcagg tggccaatag
    44761 aaaatggttt agcgatattc ggactagaca tgtcgataac aacattttct tgtttgccaa
    44821 tattttggtc agcatagtgt tctttttcag tggtaacagc ttgcaatact tgagcagaaa
    44881 tggcagattt atcaaggaaa aagttaacgt aaggtcctgt tgcgacaact ttttcaaagg
    44941 cttggctgtt cattttttca gccagttcag ccgcaatcat ttgtggtgct ttacgttcga
    45001 ctttggcaag agaaaaagca gggaaagcaa tgtctcccat ttctgagttt ttaggggttt
    45061 ccagtaactt taaaatagcc tcttggtcca ggctatcaat gatgctagat aattcgctag
    45121 caatcaattc ttttgtattc attaagagct cctttttgga cttttctact attttatcac
    45181 aattttaaag aaagaagaaa aaatttttga aatctcctgt ttttttggta taatatggtt
    45241 ataaatatag ttataaatat gcacgcaaga ggattttatg agaaaaagag atcgtcatca
    45301 gttaataaaa aaaatgatta ctgaggagaa attaagtaca caaaaagaaa ttcaagatcg
    45361 gttggaggcg cacaatgttt gtgtgacgca gacaaccttg tctcgtgatt tgcgcgaaat
    45421 cggcttgacc aaggtcaaga aaaatgatat ggtgtattat gtactagtaa atgagacaga
    45481 aaagattgat ttggtggaat ttttgtctca tcatttagaa ggtgttgcaa gagcagagtt
    45541 taccttggtg cttcatacca aattgggaga agcctctgtt ttggcaaata ttgtagatgt
    45601 aaacaaggat gaatggattt taggaacagt tgctggtgcc aataccttat tggttatttg
    45661 tcgagatcag cacgttgcca aactcatgga agatcgtttg ctagatttga tgaaagataa
    45721 gtaaggtctt gggagttgct ctcaagactt atttttgaaa aggagagaca gaaaatggcg
    45781 atagaaaagc tatcacccgg catgcaacag tatgtggata ttaaaaagca atatccagat
    45841 gcttttttgc tctttcggat gggtgatttt tatgaattat tttatgagga tgcggtcaat
    45901 gctgcgcaga ttctggaaat ttccttaacg agtcgcaaca agaatgccga caatccgatc
    45961 cctatggcgg gtgttcccta tcattctgcc caacagtata tcgatgtctt gattgagcag
    46021 ggttataagg tggctatcgc agagcagatg gaagatccta aacaagcagt tggggttgtt
    46081 aaacgagagg ttgttcaggt cattacgcca gggacagtgg tcgatagcag taagccggac
    46141 agtcagaata attttttggt ttccatagac cgcgaaggca atcaatttgg cctagcttat
    46201 atggatttgg tgacgggtga cttttatgtg acaggtcttt tggatttcac gctggtttgt
    46261 ggggaaatcc gtaacctcaa ggctcgagaa gtggtgttgg gttatgactt gtctgaggaa
    46321 gaagaacaaa tcctcagccg ccagatgaat ctggtactct cttatgaaaa agaaagcttt
    46381 gaagaccttc atttattgga tttgcgattg gcaacggtgg agcaaacggc atctagtaag
    46441 ctgctccagt atgttcatcg gactcagatg agggaattga accacctcaa acctgttatc
    46501 cgctacgaaa ttaaggattt cttgcagatg gattatgcga ccaaggctag tctggatttg
    46561 gttgagaatg ctcgctcagg taagaaacaa ggcagtcttt tctggctttt ggatgaaacc
    46621 aaaacggcta tggggatgcg tctcttgcgt tcttggattc atcgcccctt gattgataag
    46681 gaacgaatcg tccaacgtca agaagtagtg caggtctttc tcgaccattt ctttgagcgt
    46741 agtgacttga cagacagtct caagggtgtt tatgacattg agcgcttggc tagtcgtgtt
    46801 tcttttggta aaaccaatcc aaaggatctc ttgcagttgg cgactacctt gtctagtgtg
    46861 ccacggattc gtgcgatttt agaagggatg gagcaaccta ctctagccta tctcatcgca
    46921 caactggatg caatccctga gttggagagt ttgattagcg cagcgattgc tcctgaagct
    46981 cctcatgtga ttacagatgg gggaattatc cggactggat ttgatgagac tttagacaag
    47041 tatcgttgcg ttctcagaga agggactagc tggattgctg agattgaggc taaggagcga
    47101 gaaaactctg gtatcagcac gctcaagatt gactacaata aaaaggatgg ctactatttt
    47161 catgtgacca attcgcaact gggaaatgtg ccagcccact ttttccgcaa ggcgacgctg
    47221 aaaaactcag aacgctttgg aaccgaagaa ttagcccgta tcgagggaga tatgcttgag
    47281 gcgcgtgaga agtcagccaa cctcgaatac gaaatattta tgcgcattcg tgaagaggtc
    47341 ggcaagtaca tccagcgttt acaagctcta gcccaaggaa ttgcgacggt tgatgtctta
    47401 cagagtctgg cggttgtggc tgaaacccag catttgattc gacctgagtt tggtgacgat
    47461 tcacaaattg atatccggaa agggcgccat gctgtcgttg aaaaggttat gggggctcag
    47521 acctatattc caaatacgat tcagatggca gaagatacca gtattcaact ggttacaggg
    47581 ccaaacatga gtgggaagtc tacctatatg cgtcagttag ccatgacggc ggttatggcc
    47641 cagctgggtt cctatgttcc tgctgaaagc gcccatttac cgatttttga tgcgattttt
    47701 acccgtatcg gagcagcaga tgacttggtt tcgggtcagt caacctttat ggtggagatg
    47761 atggaggcca ataatgccat ttcgcatgcg accaagaact ctctcattct ctttgatgaa
    47821 ttgggacgtg gaactgcaac ttatgacggg atggctcttg ctcagtccat catcgaatat
    47881 atccatgagc acatcggagc taagaccctc tttgcgaccc actaccatga gttgactagt
    47941 ctggagtcta gtttacaaca cttggtcaat gtccacgtgg caactttgga gcaggatggg
    48001 caggtcacct tccttcacaa gattgaaccg ggaccagctg ataaatccta cggtatccat
    48061 gttgccaaga ttgctggctt gccagcagac cttttagcaa gggcggataa gattttgact
    48121 cagctagaga atcaaggaac agagagtcct cctcccatga gacaaactag tgctgtcact
    48181 gaacagattt cactctttga tagggcagaa gagcatccta tcctagcaga attagctaaa
    48241 ctggatgtgt ataatatgac acctatgcag gttatgaatg tcttagtaga gttaaaacag
    48301 aaactataaa accaagactc actagttaat ctagctgtat caaggagact tctttgacaa
    48361 ttctccactt ttttgctaga ataacatcac acaaacagaa tgaaaaggag ctgacgcatt
    48421 gtcgctccct tttgtctatt ttttaaggag aaagtatgct gattcagaaa ataaaaacct
    48481 acaagtggca ggccctggct tcgctcctga tgacaggctt gatggttgct agttcacttc
    48541 tgcaaccgcg ttatctgcag gaagtcttag gcgccctcct tgctgggaaa tatgaagcta
    48601 tttatagtat cggggcttgg ttgattggtg tggccgtagt cggtctagtt gctggtggac
    48661 tcaatgttgt cctcgcagcc tatattgccc aaggagtttc atccgacctt cgggaggatg
    48721 ccttccgtaa aattcaaacc ttttcttatg ctgatattga acaatttaat gcgggaaatc
    48781 tagtcgttcg aatgacaaat gatatcaacc agattcagaa cgttgtcatg atgaccttcc
    48841 agattctttt cagacttccc ctcttgttca tcggttcgtt tatcctagcg gttcaaacct
    48901 taccttctct gtggtgggtg attgttctca tggtagtctt gatttttggt ttgactgctg
    48961 tcatgatggg aatgatgggg cctcgttttg ccaagtttca aacccttctt gagcgcatca
    49021 atgccattgc caaggaaaat ttacgtggcg ttcgtgtggt caagtccttt gtccaagaaa
    49081 aagagcaatt tgctaagttt acagaggtct cagacgagct tcttggtcaa aacctttaca
    49141 ttggttatgc cttttcagta gtggaaccct ttatgatgtt ggttggttac ggggcggtct
    49201 tcctctctat ttggctggtc gcgggaatgg ttcagtcgga tccgtctgtt gttggttcca
    49261 tcgcttcttt tgttaattac ctaagccaga ttatctttac cattgttatg gttggatttt
    49321 tgggaaattc tgtcagccgt gccatgattt ccatgcgtcg tattcgagaa attcttgacg
    49381 cagagccagc tatgaccttc aaggatatcc cagatgaaga gttggttgga agccttagct
    49441 ttgaaaatgt gacctttacc tatccaatgg acaaggaacc gatgctgaaa gatgtgagct
    49501 ttactattga acctggtcaa atggttggtg tagttggagc gactggtgca ggaaagtcaa
    49561 ccttggctca attgattcca cgtctctttg atccacagga aggggctatc aaaatcggag
    49621 gtaaggatat tcgagaagtg agtgaaggaa ccctgcgtaa aacagtttcc atcgttctcc
    49681 aacgtgccat tctttttagt ggaacgattg cagataactt gagacagggg aagggaaatg
    49741 ctactctatt tgaaatggag cgcgcagcca atattgccca ggctagtgaa ttcattcatc
    49801 gtatggagaa aacctttgaa agtccagttg aagaacgggg aaccaatttc tctggtggac
    49861 aaaaacaaag gatgtcgatt gcgcgtggga ttgtcagcaa tccacgtatt ctgatttttg
    49921 atgattcgac ctcagccttg gatgccaaat cagagcgctt ggtgcaagaa gctttgaata
    49981 aggacttgaa ggggacgaca accattatta ttgctcaaaa aattagctcg gttgtccatg
    50041 cagacaagat cttggttcta aatcaaggac gattgattgg tcaaggcacg catgcagact
    50101 tggttgccaa caatgccgtt taccgtgaaa tctatgaaac acagaaatga aagacaaact
    50161 ataagaaaag tcaatagttt tatctaaact atttcttatt tcaatttgat gatttggcga
    50221 tgattttaga gcacggcaaa aagctattga aaaagtccat tttttcaaag gtaatcctgt
    50281 gttaatttca gaaattacat cactttttgt tcgtcaaatg gcagctcttt tttaggatat
    50341 aaaacagggt tcggataagt ttttttgcaa ggtggatgat ggctacattg taatgttttc
    50401 cttgttctaa cttagtctta agataggcct taaaagcagg tgaaaagcga gggcatgctt
    50461 tggcagcttg tatgagtacc taccgcagat gaggggaacc ccgtttgacc attctttctg
    50521 ctaaatcaat ctgacctgac tgataaatag aagaatccag tccagcgaaa gcttgtaatt
    50581 gagcaggatt atcaaaggca tgaatatttc gaatctcggc taaaatgacc gcccctaaac
    50641 gacccccaat cccagtaacc gtcgtgatga ccgagttgaa ctcagccatc aagtcattga
    50701 cacatttttt cgccttgtca atgagcctct tgtaatgttt gatgttttca ttacaagaga
    50761 taaaacgttt atgcgttatc aaactcatta ccaattgaaa caaaaagctg tggttagatc
    50821 ctttcggaaa ttgtcaagcg attggaggaa atgaactaat ccacagcggc ttattccaag
    50881 tataccactt gggctttggc agtagctaac tgcgctaaat ataatataag gaggagtaaa
    50941 atgaagacag ttcaattttt ttggcattat tttaaggtct acaagttctc atttgtagtt
    51001 gtcatcctga tgattgttct ggcgactttt gcccaagccc tctttccagt cttttctgga
    51061 caagcggtga cgcagctagc caatttagtt caagcttatc aaaatggcaa tccagaactt
    51121 gtatggcaaa gcctatcagg aatcatggtc aatcttggcc tgctggtttt ggttctattt
    51181 atctctagtg taatatacat gtgtctcatg acgcgcgtga ttgcagaatc gaccaacgag
    51241 atgcgcaaag gcctctttgg taagcttgct cagttgacgg tttctttctt tgaccgtcga
    51301 caagatggcg atatcctgtc tcattttacc agtgatttgg ataatatcct ccaagccttt
    51361 aacgaaagct tgattcaggt catgagcaat attgttttat acattggtct gattcttgtc
    51421 atgttttcga gaaatgtgac gctggctctc atcaccattg ccagcactcc attggctttc
    51481 cttatgctga ttttcatcgt gaaaatggca cgtaaataca ccaacctcca gcagaaagag
    51541 gtagggaagc tcaacgccta tatggatgag agcatctcag gccaaaaagc cgtgattgtg
    51601 caaggaattc aagaggatat gatggcagga tttcttgaac aaaatgagcg cgtgcgcaag
    51661 gcaaccttta aaggaagaat gttctcagga attcttttcc ctgtcatgaa tgggatgagc
    51721 ctgattaata cagccatcgt catctttgct ggttcggctg tacttttgaa tgataagtct
    51781 attgaaacaa gtacagccct aggtttgatt gttatgtttg cacaattttc acagcagtac
    51841 taccagccta ttatccaagt tgcagcgagt tggggaagcc ttcagttggc ctttactgga
    51901 gctgaacgaa ttcaggaaat gtttgatgca gaggaggaaa tccgacctga aaaggctcca
    51961 accttcacta agttgcaaga aagtgttgaa atcagtcata tcgatttttc atacttgcct
    52021 gataaaccta ttttgaaaga tgtcagcatt tctgccccta aaggccagat gacagcagtt
    52081 gttgggccta caggttcagg aaaaacgact attatgaacc tcatcaatcg cttttatgat
    52141 gttgatgctg gtggtattta ttttgatggt aaagacattc gtggctatga cttagatagt
    52201 cttagaagca aggtgggaat tgtattgcaa gattcggtct tgtttagcgg aacgattcga
    52261 gacaatatcc gatttggtgt gccagatgct aatcaggaaa tggttgaggt agcagcaaaa
    52321 gcaacccaca ttcacgacta tatcgaaagt ttgcctgata agtacgatac tcttattgat
    52381 gatgaccaga gcatcttttc aacagggcag aagcaattga tttcaatcgc tcgaaccctg
    52441 atgacagatc cagaagttct cattctcgat gaagcaactt caaacgtaga tacggtgacg
    52501 gaaagcaaga ttcagcatgc catggaggtg gttgtagcag gtagaactag tttcgtcatt
    52561 gcccaccgct tgaaaaccat tctcaatgca gatcagatta ttgtccttaa agatggagaa
    52621 gtcattgaac gtggtaacca ccatgaactt ttgaagctag gtggctttta ttcagaactc
    52681 tatcacaatc aatttgtttt cgaataagaa agaagttgtc ctatgtgggc agctttttct
    52741 tgtccataaa aaatgtttat cacagcctta aaaaaaacat attagacgaa agtcattttg
    52801 agtgatatga taggactatc gttagtattc gaaaggagag gcatcatggc tagaacggtt
    52861 gtaggagttg ctgcaaatct atgtcccgta gacgcagaag gcaaaatcat tcattcatct
    52921 gtatcttgta gattcgcaga gatcattcgt caagtcggtg gtctcccttt agtcattcct
    52981 gttggtgatg agtcagttgt acgtgattat gtggaaatga ttgacaaact cattttgaca
    53041 ggaggccaaa atgttcatcc tcagttttat ggagagaaaa agaccgtcga aagcgatgat
    53101 tacaatctgg tccgtgacga atttgaattg gcactcttga aggaagcgct tcgtcagaat
    53161 aaaccaatta tggcaatctg tcgcggtgtc caacttgtca atgttgcctt tggtggaacc
    53221 ctcaatcaag aaatcgaagg tcactggcaa ggactacctt tcgggacatc tcactctatt
    53281 gaaacagtag aaggaagcgt ggtggctaag ctatttggga aagaaagtca ggtcaactca
    53341 gtccatcgtc aaagcattaa agatttggca cctaatttcc gtgtaactgc tattgattca
    53401 agagaccaaa ctattgaagc gattgagtct atcgacgagc accgcattat cggtttacag
    53461 tggcatccag agtttctggt taatgaagaa gatggcaatt tagaattatt tgagtattta
    53521 ttgaatgaac tgtaacgatt ggaacatctg gtcgttcttt cttttatttt ttcaaaattt
    53581 ttagaatgtg gcattttacg caaacgtttg aattctgata aaaattggag aaattcgaca
    53641 aaaaaacttg aaaaaaacga aggtaagcgt tatgatagaa aagaagaaat attggaggaa
    53701 gaacatgtca catattaaat ttgattattc aaaagtttta gacaaatttg ttgcaccaca
    53761 tgaagtggaa tacatgcaat cacaagtaac agcagcagat gaattgatcc gtaaaggaac
    53821 tggtgctggt agcgacttct tgggatggtt ggaccttcct gaaaaatacg accgcgaaga
    53881 atttgaccgc atcttgaaag ctgctgagca aatcaagtca gacagcgatg ttttggttgt
    53941 gatcggtatt ggtggatctt accttggtgc aaaagcagca atcgacttct tgaatcacca
    54001 ttttgctaac ttgcaaacaa aagaagaacg caaagctcca caaatccttt acgcaggaaa
    54061 ctcaatctca tctacttacc ttgctgactt ggtagagtat gttgcagaca aagacttctc
    54121 agtaaacgta atttctaaat caggtacaac aactgaacca gcgattgctt tccgtgtctt
    54181 taaagaactc ttggttaaga aatacggtca agaagaagct aacaaacgta tctatgcaac
    54241 aactgaccgc caaaagggtg ctgttaaggt tgaagcagac gctaacggtt ggggaacatt
    54301 tgttgttcca gatgatatcg gtggacgctt ctcagtattg acagccgttg gtttgcttcc
    54361 aatcgcagca tcaggagctg acatcaaagc tcttatggaa ggtgcgaatg cagctcgcaa
    54421 agactacact tcagacaaaa tctctgaaaa cgaagcttac caatacgcag tcgttcgtaa
    54481 catcctttat cgtaaaggct atgcaactga gatcttggta aactatgagc catcacttca
    54541 atacttctca gaatggtgga aacaattggc tggtgaatca gaaggaaaag accaaaaagg
    54601 tatctaccca acttcagcca acttctcaac tgacttgcac tcacttggtc aatttatcca
    54661 agaaggaact cgtatcatgt ttgaaacagt tgtccgtgtt gacaaacctc gtaaaaacgt
    54721 gcttattcct actttggaag aagaccttga cggacttggt taccttcaag gaaaagacgt
    54781 tgactttgta aacaaaaaag caactgacgg tgttcttctt gcccacacag atggtgatgt
    54841 accaaacatg tatgtgactc ttccagagca agacgctttc actcttggtt acactatcta
    54901 cttcttcgaa ttggcaattg ccctttcagg ttacttgaat gctatcaacc catttgacca
    54961 accaggtgtt gaagcttata aacgtaacat gtttgccctt cttggaaaac caggatttga
    55021 agaattgagc aaagaactta acgcacgtct ataatagaag aaaagagtgg tttgcccact
    55081 ctttttactc tctttatcca tagaaattgg actcagccaa gacttgtgat ataatataga
    55141 aagcaaaaag gcagacgcct agataatagg agaaactatg tcaaaagata tccgcgtacg
    55201 ttacgcacca agtccaacag gactactaca catcggaaat gcccgtacag cattgtttaa
    55261 ctacttgtat gcgcgccatc atggtggaac atttctcatc cgtatcgaag atactgaccg
    55321 taaacgccat gtcgaggatg gtgaacgttc acaacttgaa aaccttcgct ggttaggcat
    55381 ggattgggat gaaagtccag aatcacatga gaattatcgc cagtctgagc gtttggactt
    55441 gtatcaaaaa tacattgacc aactattagc tgaaggaaaa gcctataaat cttacgttac
    55501 agaagaagag ttggcagctg aacgtgaacg tcaagaagta gctggcgaaa caccacgcta
    55561 catcaatgaa taccttggta tgagtgaaga agaaaaagcg gcttatatcg cagaacgtga
    55621 agcagctggt atcataccaa cagttcgttt ggctgtcaat gagtcaggta tctacaagtg
    55681 gcatgatatg gtcaaaggtg atatcgaatt tgaaggtggc aatatcggcg gtgactgggt
    55741 tatccaaaag aaagacggtt acccaactta caactttgcc gttgttatcg atgaccacga
    55801 tatgcaaatc tctcatgtta tccgtggaga tgaccatatt gctaatacac caaaacagct
    55861 tatggtctat gaagctcttg gttgggaagc tccagagttt ggtcacatga ccttgattat
    55921 caactctgag actggtaaga agttatctaa acgtgatact aatacacttc aatttatcga
    55981 agattaccga aagaaaggtt accttccaga agcagtcttt aactttattg ctcttcttgg
    56041 ttggaaccca ggtggtgaag atgagatttt ctctcgtgaa gaactcatta aactttttga
    56101 tgaaaaccgc ctcagcaagt caccagcagc ctttgatcag aaaaaattag actggatgag
    56161 caatgattat atcaagaatg cagaccttga aaccatcttt gaaatggcaa aaccattctt
    56221 agaggaagca ggccgtttga ctgacaaggc tgaaaaatta gttgagctct ataaaccaca
    56281 aatgaaatca gtagatgaga ttatcccatt gacagatctt ttcttctcag atttcccaga
    56341 attgacagaa gcagagcgcg aagtcatgac gggtgaaaca gttccaacag ttcttgaagc
    56401 attcaaagca aaacttgaag cgatgacaga tgatgaattt gtgacagaaa atatcttccc
    56461 acaaattaaa gcagtccaaa aagaaacagg tattaaaggg aaaaatcttt tcatgcctat
    56521 tcgtatcgca gtttcaggcg aaatgcatgg gccagaatta ccagatacaa ttttcttgct
    56581 tggacgtgaa aaatcaattc agcatatcga aaacattcta aaagaaatct ctaaataaag
    56641 aggatacaat aatggacatc tgggaaaaga tgtacgaaga agcacagaaa ctatacaatc
    56701 cacatgaagt atcagacttt gtttatgcca atcatgttgt agctgcagta gaagcaggag
    56761 atggacaaat atttacagga ttctgtatgg agggaacctg tggtgttttc catctctgcg
    56821 cagaacgggc gaccctcttc aatatgtacc aattttcagg acaaactaag gttaagaaag
    56881 tattagcctt tcgagacaaa ccaccttatg gtggaagttc agccatgcct tgcggtgctt
    56941 gtagagaatt ccttttagag cttaatgctg aaaataaaga tgcagaattc atgatggact
    57001 ataatataag aaaaacagtt aaagtcgcag aactaatccc ttattggtgg ggagaagaac
    57061 gtgcttctaa gtttaatgag tgatagaaga gtcagtataa ttctggctct ttttactata
    57121 agttgaaaaa at
//
LOCUS       DAVLAQ010000006        55895 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000006 DAVLAQ010000000
VERSION     DAVLAQ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.006"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            313..2292
                     /locus_tag="VXB71_000343"
     CDS             313..2292
                     /locus_tag="VXB71_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0450515.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKTSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            2359..3855
                     /locus_tag="VXB71_000344"
     CDS             2359..3855
                     /locus_tag="VXB71_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450516.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            3855..4781
                     /locus_tag="VXB71_000345"
     CDS             3855..4781
                     /locus_tag="VXB71_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450517.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            4790..5857
                     /locus_tag="VXB71_000346"
     CDS             4790..5857
                     /locus_tag="VXB71_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450518.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            5868..6794
                     /locus_tag="VXB71_000347"
     CDS             5868..6794
                     /locus_tag="VXB71_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450519.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            7361..8221
                     /locus_tag="VXB71_000348"
     CDS             7361..8221
                     /locus_tag="VXB71_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0450520.1"
                     /translation="MSQFITHQSLYATREGFVDELAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELVRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            8233..9126
                     /locus_tag="VXB71_000349"
     CDS             8233..9126
                     /locus_tag="VXB71_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450521.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLTGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            9139..9942
                     /locus_tag="VXB71_000350"
     CDS             9139..9942
                     /locus_tag="VXB71_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0450522.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(9975..10685)
                     /gene="treR"
                     /locus_tag="VXB71_000351"
     CDS             complement(9975..10685)
                     /gene="treR"
                     /locus_tag="VXB71_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0450523.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            10870..12837
                     /gene="treP"
                     /locus_tag="VXB71_000352"
     CDS             10870..12837
                     /gene="treP"
                     /locus_tag="VXB71_000352"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0450524.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            13015..14640
                     /gene="treC"
                     /locus_tag="VXB71_000353"
     CDS             13015..14640
                     /gene="treC"
                     /locus_tag="VXB71_000353"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0450525.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            14896..15144
                     /locus_tag="VXB71_000354"
     CDS             14896..15144
                     /locus_tag="VXB71_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0450526.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            15351..16145
                     /gene="racE"
                     /locus_tag="VXB71_000355"
     CDS             15351..16145
                     /gene="racE"
                     /locus_tag="VXB71_000355"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0450527.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            16142..17113
                     /locus_tag="VXB71_000356"
     CDS             16142..17113
                     /locus_tag="VXB71_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0450528.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            17089..17610
                     /locus_tag="VXB71_000357"
     CDS             17089..17610
                     /locus_tag="VXB71_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0450529.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            17607..18068
                     /locus_tag="VXB71_000358"
     CDS             17607..18068
                     /locus_tag="VXB71_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0450530.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            18059..18799
                     /gene="xerD"
                     /locus_tag="VXB71_000359"
     CDS             18059..18799
                     /gene="xerD"
                     /locus_tag="VXB71_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0450531.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            18799..19527
                     /locus_tag="VXB71_000360"
     CDS             18799..19527
                     /locus_tag="VXB71_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0450532.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            19546..20115
                     /locus_tag="VXB71_000361"
     CDS             19546..20115
                     /locus_tag="VXB71_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0450533.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            20102..20824
                     /locus_tag="VXB71_000362"
     CDS             20102..20824
                     /locus_tag="VXB71_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0450534.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            20824..21066
                     /gene="yidD"
                     /locus_tag="VXB71_000363"
     CDS             20824..21066
                     /gene="yidD"
                     /locus_tag="VXB71_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0450535.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(21291..22256)
                     /locus_tag="VXB71_000364"
     CDS             complement(21291..22256)
                     /locus_tag="VXB71_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0450536.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(22352..23104)
                     /locus_tag="VXB71_000365"
     CDS             complement(22352..23104)
                     /locus_tag="VXB71_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0450537.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(23101..24057)
                     /locus_tag="VXB71_000366"
     CDS             complement(23101..24057)
                     /locus_tag="VXB71_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0450538.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(24047..25006)
                     /locus_tag="VXB71_000367"
     CDS             complement(24047..25006)
                     /locus_tag="VXB71_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450539.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(25429..26130)
                     /gene="galE"
                     /locus_tag="VXB71_000368"
     CDS             complement(25429..26130)
                     /gene="galE"
                     /locus_tag="VXB71_000368"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0450540.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            26531..27595
                     /gene="pepA"
                     /locus_tag="VXB71_000369"
     CDS             26531..27595
                     /gene="pepA"
                     /locus_tag="VXB71_000369"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0450541.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            27617..27913
                     /locus_tag="VXB71_000370"
     CDS             27617..27913
                     /locus_tag="VXB71_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0450542.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            28595..29038
                     /locus_tag="VXB71_000371"
     CDS             28595..29038
                     /locus_tag="VXB71_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0450543.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            29042..29806
                     /locus_tag="VXB71_000372"
     CDS             29042..29806
                     /locus_tag="VXB71_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0450544.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVIPKVEDLTNRGKF"
     gene            29821..30549
                     /locus_tag="VXB71_000373"
     CDS             29821..30549
                     /locus_tag="VXB71_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450545.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIENGEFMVLVGPSGSGKTTMI
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLTTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            30542..32062
                     /locus_tag="VXB71_000374"
     CDS             30542..32062
                     /locus_tag="VXB71_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0450546.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            32407..33213
                     /locus_tag="VXB71_000375"
     CDS             32407..33213
                     /locus_tag="VXB71_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0450547.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(33379..33915)
                     /locus_tag="VXB71_000376"
     CDS             complement(33379..33915)
                     /locus_tag="VXB71_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0450548.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            34048..34938
                     /locus_tag="VXB71_000377"
     CDS             34048..34938
                     /locus_tag="VXB71_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0450549.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            35182..35535
                     /locus_tag="VXB71_000378"
     CDS             35182..35535
                     /locus_tag="VXB71_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0450550.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            35536..36573
                     /locus_tag="VXB71_000379"
     CDS             35536..36573
                     /locus_tag="VXB71_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0450551.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIIIE"
     gene            complement(36620..37627)
                     /gene="galR"
                     /locus_tag="VXB71_000380"
     CDS             complement(36620..37627)
                     /gene="galR"
                     /locus_tag="VXB71_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0450552.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            37792..38970
                     /locus_tag="VXB71_000381"
     CDS             37792..38970
                     /locus_tag="VXB71_000381"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0450553.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            38989..40470
                     /locus_tag="VXB71_000382"
     CDS             38989..40470
                     /locus_tag="VXB71_000382"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0450554.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            40540..40944
                     /locus_tag="VXB71_000383"
     CDS             40540..40944
                     /locus_tag="VXB71_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0450555.1"
                     /translation="MKDFHFDAISAFESYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            41125..41889
                     /locus_tag="VXB71_000384"
     CDS             41125..41889
                     /locus_tag="VXB71_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV0450556.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            41886..42347
                     /locus_tag="VXB71_000385"
     CDS             41886..42347
                     /locus_tag="VXB71_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0450557.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(42398..43660)
                     /locus_tag="VXB71_000386"
     CDS             complement(42398..43660)
                     /locus_tag="VXB71_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0450558.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGNGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(43660..44241)
                     /locus_tag="VXB71_000387"
     CDS             complement(43660..44241)
                     /locus_tag="VXB71_000387"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0450559.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(44641..44736)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(45119..45358)
                     /locus_tag="VXB71_000388"
     CDS             complement(45119..45358)
                     /locus_tag="VXB71_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0450560.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(45403..45501)
                     /locus_tag="VXB71_000389"
     CDS             complement(45403..45501)
                     /locus_tag="VXB71_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0450561.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            complement(45513..46340)
                     /gene="xth"
                     /locus_tag="VXB71_000390"
     CDS             complement(45513..46340)
                     /gene="xth"
                     /locus_tag="VXB71_000390"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0450562.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            46474..46930
                     /locus_tag="VXB71_000391"
                     /pseudo
     CDS             46474..46930
                     /locus_tag="VXB71_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            46927..47457
                     /locus_tag="VXB71_000392"
     CDS             46927..47457
                     /locus_tag="VXB71_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0450563.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            47585..49330
                     /locus_tag="VXB71_000393"
     CDS             47585..49330
                     /locus_tag="VXB71_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450564.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            49320..51071
                     /locus_tag="VXB71_000394"
     CDS             49320..51071
                     /locus_tag="VXB71_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450565.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            51244..51936
                     /locus_tag="VXB71_000395"
     CDS             51244..51936
                     /locus_tag="VXB71_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0450566.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            51979..53205
                     /locus_tag="VXB71_000396"
     CDS             51979..53205
                     /locus_tag="VXB71_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0450567.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            54369..>55895
                     /gene="pfbA"
                     /locus_tag="VXB71_000397"
     CDS             54369..>55895
                     /gene="pfbA"
                     /locus_tag="VXB71_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0450568.1"
                     /translation="MKYFVPNEVFSIRKLKVGTCSVLLAISILGSQGILSDEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNS
                     NNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     E"
BASE COUNT        16305 a        10484 c        12651 g        16455 t
ORIGIN      
        1 aaactgaatc ttgaatacta gaatgatact tctacaatat tgttataatt taatttgaat
       61 tccaaaatca cattgttccg tccgtatttc attttactgt atgtcttcct aaactccaaa
      121 gtttctgcgt caaatttcct attttcactg tagtctttga cacttcgaac gacaatttga
      181 atcatatatt caaaaaaaaa tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt
      241 tgtttgattt ttaatggata atgtgatata atggttgtca atctataatt cacataaaca
      301 gaggagtaga aaatgaaaaa aaatcgtgta tttgctacag caggtcttgt tttattagca
      361 gcaggtgtac ttgcagcatg cagttcttca aaaacatctg attcatcagc ccctaaagct
      421 tatggctatg tttatacagc agacccagaa accttggact acctgatttc aagtaaaaat
      481 agtacaacag tagtgacttc aaatgggatt gatggtttat tcactaacga taattacggt
      541 aatcttgctc ctgcagttgc agaggattgg gaagtctcta aggatggttt gacctacact
      601 tataagattc gtaaaggggt taaatggttt acctctgatg gagaagaata tgcagaggtg
      661 acggctaaag atttcgtgaa cggtttaaaa cacgcagcag ataaaaaatc agaagctatg
      721 tatttagctg aaaattcggt taaaggcttg gcagattatc tatcaggaac ttcaacagat
      781 ttttcaacag ttggtgtcaa ggcggttgat gattatacgt tacaatacac tttgaaccag
      841 cctgaaccgt tctggaactc taagttgacc tattctattt tctggcctct gaatgaagaa
      901 ttcgaaacat caaaaggaag cgattttgct aaaccaacag atccgacatc cttgctttat
      961 aatggtccat tcttgttgaa agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat
     1021 gagcaatatt gggataaaga aaatgtccac ctagatacta tcaatctagc ttactatgat
     1081 ggatcagatc aggagtcgct agagcgtaac ttcactagtg gagcttatag ttatgcccgt
     1141 ctttacccta ccagctccaa ctattctaag gttgcagaag aatacaagga caatatctat
     1201 tacacacaat caggctctgg gattgctggt ctgggtgtga atattgatcg ccaaagttac
     1261 aactatactt ctaaaactac agattcagag aaagtagcta ctaagaaggc attgcttaac
     1321 aaagatttcc gtcaagcctt gaattttgct cttgatcgct cagcttactc agctcaaatc
     1381 aatggtaaag atggagcagc tttagcagtt cgtaatttat ttgtaaaacc agactttgtt
     1441 tcagctggtg agaagacctt tggtgattta gtcgctgctc aacttcctgc ttatggtgat
     1501 gagtggaaag gtgtgaattt agctgatggg caggatggtt tattcaatgc tgacaaggcc
     1561 aaggcagagt ttgcgaaagc taagaaagct ttagaagcag acggcgttca gtttcctatt
     1621 catctggacg ttccagtaga ccaagcatca aaaaactata tatctcgtat tcagtccttt
     1681 aaacaatctg tagaaacagt tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg
     1741 acaagtgatg aattccttaa tattacttac tatgctgcca atgcttcatc tgaggattgg
     1801 gatgtatcgg gaggagtttc atgggggcca gactatcaag acccatctac ttacctggat
     1861 attttaaaaa caactagcag tgaaactaca aaaacatatt taggatttga taatccaaat
     1921 agcccttcag tagttcaagt tggtttgaaa gaatacgata aattagttga tgaagctgcc
     1981 aaagagacaa gcgacttgaa tgtccgttat gaaaaatatg cagcggctca agcatggttg
     2041 acagatagtt cactctttat tcctgctatg gcttcttctg gtgcagcacc agtgctttca
     2101 cgaattgttc catttactgg agcttctgcg caaacaggct ctaaggggtc agatgtttac
     2161 ttcaaatatt tgaaattaca agataaagcg gtgactaagg aagagtatga aaaagctcgt
     2221 gaaaaatggt tgaaagaaaa agctgaatca aatgagaaag ctcaaaaaga attggcaagt
     2281 catgtgaagt aaataatttc taatagaact ttctctccat gaggagaagg ttcttttggg
     2341 atttttaaag gaaataatat gaaaaaatat atttttatgc gtgttttgcg gtcattggtt
     2401 tcgattttct tagtaacgac tttgacctac acgattatct ataccttggt tcctcgaaaa
     2461 ttgattttca agcaggatcc taactataat aaaattgcga caacggctga taaacgtgat
     2521 aactatgaaa atactgtgtt tgagcgtatg ggctacattg agtattacga tactaaagag
     2581 ttgcaagaaa aggcaagtag catggattct tctgtaacag tagaagcaaa tgcgaccaat
     2641 aaagctattt atgaaaagta catcaatcaa ttaggtcatg gttggacttt gggagaattt
     2701 actgaaagtg gtcaattcta tgctactcgt gaaattccaa tttttgaacg tgtttttcac
     2761 ttctatgcta acttgattga cattgaccat acaaataaaa tccaagaccc tgaaaatcca
     2821 gacttgaaac gctaccttcg ttttgaaaac gatccagcta tcggatggtc attggtcggt
     2881 tcaggaacta aacataaata tctcttgtac tttaacagtc agttcccatt tgttcatcaa
     2941 aactttgtga acttgaattt aggtgactct tacccaacct atgctaatac accagttctt
     3001 caggttatta ctcaaggtca aggacaaacc aaaactgccc aagttcagtt cccaacaggt
     3061 aagaaaacgt cttctgtaaa tatttactca agaacctaca agtcacctag tcaggctgac
     3121 tctcgtgaag tagctagcta tgggaaagat gatccttata cagcgactga aagtaattac
     3181 caatatccat ctatgattgt cagctctgct attactggtt tgattggttt ggttcttgcc
     3241 tatgctcttg ccgtgccact tggttcagcc atggctcgtt tcaagaacac ttggattgat
     3301 agcctctcaa caggggcttt gaccttcttg cttgctcttc caacgattgc cttggtttac
     3361 atcgttcgat tgattggatc atctatttcc cttccagatt cattccctat cttgggagct
     3421 ggagattggc gttcttacgt tttaccagca gtcatccttg gtttgttggg tgctcctggt
     3481 acagccattt ggattcgtcg ttacatgatt gacttgcaat ctcaagactt tgttcgtttc
     3541 gctcgtgcaa aaggtttgtc tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc
     3601 atggttccgc tggtttcagg aattcctggt gccattattg gggttatcgg tggtgcaacc
     3661 cttactgaaa cagtcttcgc cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa
     3721 gcatctaata actctatggt cgttggtctt gtcttcatct ttacatgtat ttctatcttc
     3781 tcacgtcttt tgggagatat ttggatgact attattgacc cacgtattaa attgactgag
     3841 aaaggaggca aataatgtct acaatcgata aagaaaaatt tcagtttgta aaacgtgacg
     3901 attttgcctc tgaaactatt gatgcgccag catattctta ctggaaatca gtgtttaaac
     3961 aatttatgaa gaaaaaatca actgtagtca tgttgggaat cttggtagcc atcattttga
     4021 taagtttcat ctacccaatg ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg
     4081 actttagtgt tcgttatatc aagccaaatg cggagcattg gttcggtact gacagtaacg
     4141 gtaaatcgct ctttgacggt gtctggttcg gagctcgtaa ctccatcctc atttctgtga
     4201 ttgcgacagt gattaacttg gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa
     4261 aatcagttga ccgtgtcatg atggaagttt acaacgtcat ctcaaacatc ccacctcttt
     4321 tgattgttat tgtcttgact tactcaatcg gagctggatt ctggaatctg atttttgcca
     4381 tgagcgtaac aacatggatt ggtattgcct tcatgatccg tgtgcaaatc ttgcgctatc
     4441 gtgacttgga atacaacttg gcgtcacgta ctttgggaac accaaccttg aagattgttg
     4501 ccaaaaatat catgcctcaa ttggtatctg ttattgtgac aaccatgact caaatgcttc
     4561 caagctttat ctcatacgaa gccttcttgt ctttcttcgg tcttggatta ccgattacag
     4621 tgccaagttt gggtcgtttg atttcggatt attcacaaaa cgtaacaacc aatgcttact
     4681 tgttctggat tccattgaca acccttgtct tggtatcctt gtcccttttc gtagttggtc
     4741 aaaacttagc ggatgctagt gatccacgta cacatagata ggagtagaaa tgacaaaaga
     4801 aaaaaatgta attttgactg ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt
     4861 attgacagcc attcgcggcg tttcccttga actagtcgaa ggagaagtat tagccttggt
     4921 aggtgagtca ggatcaggta aatctgtttt gacaaagacc ttcacaggta tgctcgaaga
     4981 aaatggtcgc attgcccaag gtagtattga ctaccgtggt caggacttga cagctttatc
     5041 ttctcacaag gattgggaac aaattcgtgg tgctaagatt gcgactatct tccaggaccc
     5101 aatgactagt ttggacccca ttaaaacaat tggtagtcag attacagaag ttattgtaaa
     5161 acaccaagga aaaacagcta aagaagcgaa agaattggcc attgactaca tgaataaggt
     5221 tggcattcca gacgcagata gacgttttaa tgaataccca ttccaatatt ctggaggaat
     5281 gcgtcaacgt atcgttattg cgattgccct tgcctgccga cctgatgtct tgatctgtga
     5341 tgagccaaca actgccttgg atgtaactat tcaagctcag attattgatt tgctaaaatc
     5401 tttacaaaac gagtatcatt tcacaacaat ctttattacc cacgaccttg gtgtggtggc
     5461 aagtattgcg gataaggtag cggttatgta tgcaggagaa atcgttgagt atggaacggt
     5521 tgaggaagtc ttctatgacc ctcgccatcc atatacatgg agtctcttgt ctagcttgcc
     5581 tcagcttgct gatgataaag gggatcttta ctcaatccca ggaacacctc cgtcacttta
     5641 tactgacctg aaaggggatg cttttgcttt gcgttctgac tacgcaatgc agattgactt
     5701 cgaacaaaaa gctcctcaat tctcagtatc aaagacacat tgggctaaaa cttggcttct
     5761 tcatgaggat gctccaaaag tagaaaaacc agctgtgatt gcaaatctcc atgataagat
     5821 ccgtgaaaaa atgggatttg cccatctggc tgactaggag gaaggaaatg tctgaaaaat
     5881 tagtagaaat caaagattta gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg
     5941 ttaaaaatgc taacttcttt atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg
     6001 gtagtgggaa aacaactatt ggtcgtgcta tcatcggtct aaatgataca agtaatggag
     6061 atatcatttt tgatggtcaa aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat
     6121 tgattcgtcg aatccagatg attttccaag accctgccgc aagtttgaat gaacgtgcga
     6181 ctgttgatta tattatttct gaaggtcttt acaatcaccg tttatttaag gatgaagaag
     6241 aacgtaaaga gaaagttcaa aatattatcc gtgaagtagg tcttcttgct gagcacttga
     6301 ctcgttaccc tcatgaattc tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct
     6361 tggtcatgca accagacttt gttattgcag atgagccaat ttcagccttg gacgtttctg
     6421 tacgtgccca agtcttgaac ttgctcaaaa aattccaaaa agagctcggc ctgacctatc
     6481 tcttcatcgc ccatgacttg tcggttgttc gctttatttc agatcgtatc gcagttattt
     6541 acaagggtgt tattgtagag gttgcagaaa cagaagaatt gtttaacaat ccaattcacc
     6601 catatactca agccttgctt tcagcggtac caatcccaga tccaatcttg gaacgtaaga
     6661 aggtcttgaa ggtttacgac ccaagtcaac acgactatga gactgataag ccatctatgg
     6721 tagaaatccg tccaggtcac tatgtttggg cgaaccaagc cgaattggca cgttatcaaa
     6781 aaggactaaa ctagtaatgg ttttataatt tccatgtcaa tttttatgga aattataaaa
     6841 ctttttttgt tggactgatt tgaaaaactt tgaaagcttc ctgaaagaat ttttgaaaaa
     6901 ttttaaaaat tatgaaatgt tattgacagg tgatgaaaaa ggtggtagga caggaagcat
     6961 caaaaaagaa agcagaaaaa gaaatgaata agagacaagc cgtaactatg aatcaaaact
     7021 tttactttag ctactttaga tagtgtttgt agacatgtca ccatggatgc aaacagttca
     7081 agcaatttgt ttgtatctat gtggctaaga tttttgattg tggtccatat agatgaatat
     7141 ctaaatggac tagctaagtt gtaacttgtt aggttatttc aagtatccgt ttagatagta
     7201 tctaggcggt tttttgtttt atcttttctg agaaggagtt tcattatgaa agttgttcga
     7261 aaatcactag ccccctcttg gtagtggggc tcctcttgac ttctctgatc agtttgcatc
     7321 agttgaaggc agataagaaa aagatgtctt tcgtatcggt atttcgcaat ttattaccca
     7381 ccagtcctta tacgctacta gagaaggatt tgtggatgag ctggccaaac aaggctatgt
     7441 tgagggggaa aatattgaga ttgatttgca aaatgcacag ggagaacaaa gaaatctaaa
     7501 aacgatttcc cagcaactag cagaatccag cgatgtcgtt ctagccatcg caaggccttc
     7561 tgctcagagc ttggccaata cgacgcaaac gacaccagtt atcttttcag ctgtaacaga
     7621 cccagtcagt gccaagttgg ttgagtcaag agaacatcct gggggcaatg taactgggac
     7681 aagcgatcag tcatcagatg ccatttcaac ccaaatcaat ttgataaaga aagtgttgcc
     7741 aaaggctaaa acgattggaa tcctctatac tcagagcgag cccaattcgg ttgttcaaaa
     7801 ggatgaagct aagcgacttc tgaaagaaaa aggctttacc gttgttgaaa aaacaatctt
     7861 ggacagtaat aacgtcaagg cggcagcaga gagtttgatg gcagaggtgg atatggtttt
     7921 tgtcccaact gataatatca tttcgttaac catggaaaca gttaagcagg tttctattaa
     7981 acacaaggtt ccagtattcg gtggttcaac agaaatgatt gctgttggtg gcttgtataa
     8041 ctacggaacc aattatgaag aattggtacg tcagacagct cgcatgctga ttcgtgtttt
     8101 aaaaggtgag aaaccagaaa atatagcagt tgagttgcct gaaaaactgg aattgcatac
     8161 caatcaagaa atggcagatg cattgggaat tgatattagt aagttagaag gcaaggaata
     8221 aggaggatta agatgaattt tgtgttatct agtttatcag aaggtttgtt gtggtcgatt
     8281 gtggcgattg gggtctactt gactttccgt attttggata ttgcggatat gactgctgag
     8341 ggagcctttc ctctgggggc agcagtcgtt gtatcacaga tacaggcagg ggcaaatcct
     8401 tggcttgcga ctttacttgc tttgctgaca ggtatggtag caggtcttgt atcaggaatg
     8461 ctccacacca agatgaaaat cccagctctc ttgacaggga ttgtgacctt gacagggctc
     8521 tattcaatca atattaaaat catgggcagt gtacccaatc tttccttggg agattctgca
     8581 accgtcttta aacagttggc gagcttgggt ctgacaaatg aaggaactgt tttctcactt
     8641 agtttggcct gttttttact tgtttgtttg gtcttgaccc ttttgatgaa aacagagatt
     8701 ggcctggtct tgcgttcgac tggggataat atcccgatga gtgaggccaa tggagtcaat
     8761 gtagacacca tgaagattgt tggttacatg atttcaaacg gtttgattgc tctatgtggt
     8821 tccttgtttg cccaaaatga tggattttca gatgtgactt ctgggacagg aaccattgtt
     8881 gttggtttga gctcggtgat tattgcggaa gtcttgatac acgacttgac cattggaggc
     8941 cgcttattat ccatcggaat cggtgctatt gtttaccgtt tgattatttt aaatatctat
     9001 gaaattccaa atctagatca aaacttggta cgtctcttta atgcaatctt gctcgctttg
     9061 gttttatttg caccagaatt gcaaaagaga ttaaagattc gtggtctgaa attgagaaat
     9121 gaataggagg agaaagttat gacaagtttg ttaacacttg aaaatattca caagacattt
     9181 gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat tagatttaga ggttgaagag
     9241 ggagatttta tctctgtgat tggtggaaat ggagcaggaa aatccacttt gatgaatatc
     9301 ttggctggca atctatcggt ggacgaaggg gaccttctac tggcagggaa atccattaaa
     9361 aatctgagtg tcagaaagag agccaaggat attgcccgtg tttttcaaga tcctaagatg
     9421 ggaacagctt ctcgtttgac gattgaggag aatatggcta ttgccttgag acgcgggcag
     9481 aagagagggc ttggttgggg cgtgaaggag aaggatagaa tccagttcca agaggccttg
     9541 aaggagttga atattggtct tgaaaaccgc ttaaaagtag atactcaata tctctcagga
     9601 ggacaaagac aggctttgac tctagtcatg acagatctga tgaaaccaaa acttttactt
     9661 ttggatgaac atactgcggc acttgacccg aaaaccagtc aaatggtgat ggacttgacg
     9721 caaaagattg tggagcacca tcagtggacg actttgatga ttacccatga tatgaatcat
     9781 gcgattgagt acggcaatcg tctcattatg ctctatcaag gcaagatagt ggtggatgtc
     9841 aagggagaag agaaaaagca tctgacagtt gaagacctta tgcatctctt ccagaaaaat
     9901 agtggccaaa gtctggtcag tgatgaatta gttttgggat aaagaaaaag gctgagatct
     9961 ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta caaatctaaa tttctctaac
    10021 ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt ggagatagac ttttgattta
    10081 atcgaaacga cataagggtc tttgccaatg tccatgagaa tcttgtctcg gtcgcttgag
    10141 tggtcaatgg tgatttcctt ctgagcataa tcaataagga gtttgaggcc attttctata
    10201 taagaataga tagactgctc agcaatttgg cgagtgagat ttggaattag ttccatatcc
    10261 agatagtccg tatccagaac ggataccaga tcatccacca cacgctggcg gaccaccttc
    10321 caaaccatcc gaaactctgg gaaaccggtt atcagtgagg attttttatc aataataatc
    10381 ttgtccagac tgaccacgtt ggttttagag cgcagtccaa gttctttaac tagttcttgg
    10441 tagctggtta ggttggatac agggaaattg acggtttctt ctttgacgac ttgagaacct
    10501 tgctctctta tctttttgat caatccttcc tcttggagga gagacagggc ctttcggacg
    10561 gtatcacgac tcacttgata ttgctccata aggtcgtgct cgctaggaag gaaatctccg
    10621 acagcgtaag tctcgttttg aatggtttct tggatttgct taaataattg ttggtatttc
    10681 ttcattttgc ctgctttaat aggtttttag tctagtttaa tgaacacctg tatctatttt
    10741 accatacaag tgctagaaaa tttacaaaaa aacacccttt ttataccaaa caagttgcag
    10801 acaagtttgg tatcgtttac aatatactta tcaaatcaaa cttgctttga caagtataag
    10861 gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc tgcttcaggc aattggaggc
    10921 aaagaaaatg tgactgccgt aactcactgt gcgacacgga tgcgctttgt tttaggagat
    10981 gataagaagg ctaatgttaa agctatcgag tcaattccag ctgttaaagg aacttttaca
    11041 aatgcaggtc aatttcaggt aatcattgga aatgacgtgc ccatctttta taatgatttt
    11101 acagccgttt caggtattga gggtgtttcc aaagaagcag ccaagtctgc agctaagagt
    11161 aatcaaaacg tggtccaacg tgttatgacc actctggcgg agatttttac tccgattatt
    11221 ccagccttga tagtcggagg attgatcctc ggtttccgta atgtcttgga aggtgtccat
    11281 tggtcgatgt tggatggcaa gaccatcaca gaatcctctc agttttgggc aggtgtcaat
    11341 cacttcctct ggttgcctgg tgaagctatc ttccagttct taccagtagg gattacttgg
    11401 tctgtttctc gtaagatggg aaccagccaa attttgggaa ttgttctcgg aatctgtttg
    11461 gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa cgccagcagc tgatatcgcg
    11521 gcaaactggg tttggaattt tggctatttt actgttaatc gtatcggtta ccaagcccaa
    11581 gttatcccag ccttgcttgc aggtttgagt ctgtcttatc ttgaaatctt ctggcgcaag
    11641 catatcccag aagtcatttc tatgattttt gtacctttct tgtcattgat tccagccttg
    11701 attttggctc atactgtttt gggaccaatc ggttggacaa ttggacaagg actttcatca
    11761 gttgtcttgg caggtttaac tggtccagtt aaagggctct tcggtgcaat ttttggtgcc
    11821 ctctacgctc catttgtcat cacaggtctg caccatatga ccaatgccat tgatacacaa
    11881 ttgattgcgg atgctggtgg cactgcccta tggccaatga ttgctctttc taatattgct
    11941 caaggctcag ccgtgtttgc ctattatttc atgcatcgcc atgatgagcg tgaggctcag
    12001 gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta cagaaccagc tctttttggg
    12061 gttaacgtaa aatatattta tccatttgtt gctgggatga ctggttcagc ccttgcaggc
    12121 atgttatccg ttacttttaa tgtaactgcg gcttctattg gtatcggtgg tttgccaggt
    12181 attctctcta ttcaacctca atacatgctg ccatttgcag gaactatgct agttgcgatt
    12241 gttgttccaa tgctcttgac tttcttcttc cgcaaggctg gtctctttac aaaaacagag
    12301 ggcgatacga acttgcaggc agaattcgtt gctcaagaag aagcagaatt tgtgaaccat
    12361 gaaccagtag aacttacttc ggtagaaatt atcagcccac taactggcca agtgaaagaa
    12421 ttgagtcaag cgacggatcc tatttttgca tcaggtgtca tggggcaagg tctggtcatt
    12481 gaaccaagcc aaggtgagtt gacctctcca gttaatggga cagtgacggt tcttttccct
    12541 accaagcatg ccatcggcat tgtctctgac gagggagttg aattgctcat ccacatcggt
    12601 atggatacag taggtcttga tggcaaaggt tttgaaagtc ttgtagtcca aggagatcac
    12661 gttacagttg gtcagcaact gattcgtttt gatatggatg tcattaaggc tgcaggtctg
    12721 gtgacagaaa ctcctgttat catcaccaac caagatgctt atacagcgac tattcccgga
    12781 acttatccga caacgattca agctggagca tctctcatgg tcgctacacg aatctaatac
    12841 tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaac agtgttttga
    12901 gcaacctgtg gctagcttcc tagtttgctc tttgattttc attgagtata attgaaatag
    12961 cacaaatagg gacggaagac tgcttcctcc cttttatcag aaaaggagaa acagatgaca
    13021 cttgataaag gaaaagtagt ctatcaaatc tatccaaaat cttacaaaga caccactgaa
    13081 aacggtattg gggatttccg tgggattatc gaaaaaattc cctatttagc caaactaggc
    13141 gtggatatgg tctggctcaa tccattctat ccaagccctc aacgggataa tggttacgat
    13201 atttcagatt atatggcagt ggatcctctt tttggtgata tggctgattt tgaggaaatg
    13261 gtgtgtgtcg gtaaagagca caagattgac tttatgctgg acatggtact taatcattgt
    13321 tcgacagagc atgaatggtt tcagaaagcc ctagctggtg ataagtatta tcaagacttt
    13381 ttcttcatcc aagaccaacc aacagattgg cagtctaagt ttggtggttc tgcatgggcg
    13441 cctttcgggg atactgggaa atactatctt cacctatttg atgagaccca ggctgacctt
    13501 aactggcgca attccaatgt ccgtaaggag cttttcaagg ttgttaattt ctggcgcgac
    13561 aagggtgtca aaggtttccg atttgatgtg atcaatttga tcggtaagga cgaggtttca
    13621 gtggactgtc ctgaaaatga agggaagcca gcttatacag acaaacccat cgttcataac
    13681 tatttgcgta tgatgaacca agccactttt ggatctgacg atagctttat gacagttggg
    13741 gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt cgtcgcctga tcgtcaggaa
    13801 ttatccatga cctttaattt tcatcacctc aaggtggact ataaggatgg acaaaagtgg
    13861 accttggctc cctttgattt tgaagagttg aagagtcttt accatagttg gggtaaggaa
    13921 atgagtgata aagacggttg gagtgccctc ttttggaaca atcacgatca accacgtgcc
    13981 ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag gagccaccat gctagcagcc
    14041 agcattcacc tgtcacgtgg gacaccttat atctacatgg gtgaggaaat cgggatgatt
    14101 gacccagact atgattctat ggctgattat gtggatgtcg aatcgcttaa tgcctatcag
    14161 atgctcttag aagaaggaaa gagtcagcaa gaagccttcc agattattca agctaagtcg
    14221 cgtgataatt cacgtattcc catgcagtgg gatacttctg aaaatgcagg attttcaaca
    14281 ggcactccat ggttgaaagt cggtaaatcc tataaagata tcaatgtaga aaatgaaatc
    14341 aaaggtctga ttttcacctt ctatcaagac ttgattcgac tgcgtaagga aatgccaatc
    14401 atttcagaag gaaattacaa accagccttt gaagatagca aacaagtcta cgcttttgaa
    14461 cgccagtttg aggatcaaaa gttactagtg ctcaataact tttatgccaa agaagtggaa
    14521 atcgacttgc cagcagtcta ccaaaatgga cagattttga tttcaaacta tgaagatgca
    14581 gaagtgtctg agaaaattct actcaaaccc tatcaaacac tggctattta tgtaaattaa
    14641 tactcttcga aaatctcttc aaaccgtgtc agttttatct gtaacctcaa agcggtgctt
    14701 tgagcaacct gtggctagct tcctagtttg ctctttgatt ttcattgagt ataaacttag
    14761 caaggagacc tctttttcag aaaagcaggg ttctttttgc tgtctattcc atccttgaaa
    14821 gtgtagaaca aactggtcag ggtggctagt ttgtggtata atgaaaggga ttcaaaaaga
    14881 aacaggagaa aaatgatgga tttactttta gcaattgtat tgattgtgct agcttttcta
    14941 ggaggagctc ttggaggaat gtacttggtt cgtaagcaaa tcgaaaaaga atttgctgac
    15001 aacccacgtt tgaatgctga agcagttcgt actcttttga gtgcaaatgg tcaaaaacca
    15061 agcgaagcta aggtacaaca agtttaccac caaatcatcc gccaacaaaa ggcagccctt
    15121 gctaacaata aaaagaaaaa ataaataagg aaaagtctgg gatgaaagtt ccagacttct
    15181 cactatgttg gttatggttt agggatgaga ctttttcctt gcattctatt gatatttgat
    15241 tatgattaag agagaggtag ttgacattct atcaagctgt cggtcagttc gttcagtaca
    15301 aggaatcata atgaacgatc aatcagaaaa aagactagaa agaagactgt atggataatc
    15361 gaccaattgg ttttttggat tcgggtgtcg ggggcttgac cgttgtgcgc gagctcatgc
    15421 gccagcttcc ccatgaagaa atcgtctata ttggagattc ggcgcgggcg ccctatggcc
    15481 cccgtcctgc tgagcaaatt cgtgaatata cttggcagct ggtcaacttt ctcttgacca
    15541 aggatgtcaa aatgattgtc attgcttgta acactgcgac tgcggtcgtc tgggaagaaa
    15601 tcaaggctca actagatatt cctgtcttgg gtgtaatttt gccaggagct tcggcagcca
    15661 tcaagtccag tcaaggtggg aaaatcggag tgattggaac gcccatgacg gtacaatcag
    15721 acatataccg tcagaaaatc catgatctgg atcccgactt acaggtggag agcttggcct
    15781 gtcccaagtt tgctcccttg gttgagtcag gtgccctgtc aaccagtgtt accaagaagg
    15841 tggtctatga aaccctgcgt cccttggttg gaaaggtgga tagcctgatt ttgggctgta
    15901 ctcattatcc actccttcgc cctattatcc aaaatgtgat ggggccaaag gttcagctca
    15961 tcgatagtgg ggcagagtgc gtacgggata tctcagtctt actcaattat tttgaaatca
    16021 atcgtggtcg cgatgctgga ccactccatc accgttttta cacaacagcc agtagccaaa
    16081 gttttgcaca aattggtgaa gaatggctgg aaaaagagat tcatgtggag catgtagaat
    16141 tatgacaaat aaaatttatg aatataagga tgaccaggac tggtatgttg ggtcttatag
    16201 tatttttggt ggcgttaaca gtttgagcga ctataagaca gattttcctc tgtttgaatt
    16261 ctccaaaata tttggagatg aagagtatgg tttcccgctt tcagttactg ttttacgcta
    16321 tggttctacc taccgtttgt tctcctttgt ggtagacatg cttaatcaag aaatgggacg
    16381 aaacttggaa gttattcaac gtcatggggc cctgctcttg gttgaaaatg ggcaactctt
    16441 gtatgtagaa ttgcctaaag aaggggtcaa tgttcatgat ttctttgaga caagcaaggt
    16501 cagagaaacc ttgttgattg cgactcgtaa cgaaggtaaa accaaggaat tccgagctat
    16561 ctttgataag ttaggctacg atgtggaaaa tcttaatgac taccctgacc tgcctgaagt
    16621 agcagaaaca ggtatgacct ttgaagaaaa tgcccgcctt aaggcagaaa ccatttctca
    16681 attaacgggc aagatggttt tggcagatga ttctggtctc aaagtcgatg tccttggtgg
    16741 cttaccaggc gtctggtcag ctcgtttcgc aggtgtggga gcaactgacc gtgaaaataa
    16801 tgccaaactc ttgcacgaat tggccatggt ctttgaactc aaggaccgct cggctcagtt
    16861 ccacacaacc ctagtcgtag ccagcccaaa taaggaaagt ttagttgttg aagcagactg
    16921 gtcaggttat attaactttg aacctaaggg tgaaaatggc tttggctatg atcccctctt
    16981 ccttgtagga gagacaggtg agtcatcagc tgaattaacc ctagaagaaa aaaatagtca
    17041 atctcaccgt gccttagccg ttaagaaact tttggaggta tttccatcat ggcaaagcaa
    17101 accatcattg taatgagcga ttcccatggc gatagcttga ttgtggaaga agtccgtgat
    17161 cgctatgtgg gcaaagtcga tgccgttttt cataacggcg attctgaact acgtccggat
    17221 tctccacttt gggagggcat ccgcgttgtt aaagggaaca tggacttcta cgccggctac
    17281 ccagaacgtc tggtgactga gcttggttcg accaagatta tccaaactca tggtcacttg
    17341 tttgacatca atttcaactt tcaaaagttg gactactggg ctcaggagga agaggccgct
    17401 atctgcctct atggtcactt gcatgtgcca agtgcttggt tggaaggcaa gatcctcttt
    17461 ctaaatccag gttctatcag tcaaccacga ggtaccatca gagaatgtct ctatgctcgt
    17521 gtggagattg atgatagtta cttcaaagtg gactttttga cacgagatca cgaggtgtat
    17581 ccaggtttgt ccaaggagtt tagccgatga ttgccaagga gtttgagact ttcttgttgg
    17641 ggcaggagga aacttttttg acccctgcta aaaatctagc tgtgttgatt gatacccaca
    17701 atgcggatca tgcgaccctc ttgctcagtc agatgaccta tacccgtgtt cccgttgtga
    17761 cagatgaaaa acagtttgtt gggacgattg gactcagaga tattatggct tatcagatgg
    17821 agcatgactt gagccaagaa atcatggcgg atacggatat cgttcatatg acaaaaacgg
    17881 acgtagcggt tgtttcgcct gatttcacca ttacggaggt cttgcacaag ctagtagatg
    17941 agtccttctt accggtcgtg gatgcagagg gtattttcca agggattatt acgcgcaagt
    18001 ccatcctcaa ggccgttaat gccctcttgc atgactttag taaggaatat gagattcgat
    18061 gccaatgaga gacaggattt cagccttttt agaggaaaag cagggcttgt ctgtcaattc
    18121 caagcagtcc tataagtatg atttggagca atttttagac atggtaggtg agcggatttc
    18181 tgagaccagt ctcaagattt accaagccca gctagccaat ctaaaaatca gcgcccagaa
    18241 gcgaaagatt tcggcctgta accaatttct atactttctc tatcaaaaag gagaggtgga
    18301 cagcttttac cgcttggaat tagccaaaca agctgaaaag aagacggaaa agccagagat
    18361 tctataccta gactcttttt ggcaggaaag cgaccatcca gagggccgct tgctagcgct
    18421 cttaatccta gaaatggggc tcttgcccag tgagatttta gccatcaagg ttgcggacat
    18481 caatctggat tttcaggtgc tgcgaatcag caaggcttcc caacagagga ttgtcaccat
    18541 tcccacggcc ttgctttcag aattggaacc cttgatgggg cagacctatc tttttgaaag
    18601 aggagagaaa ccctattctc gtcagtgggc ctttcgtcag ttagaatctt ttgtcaagga
    18661 gaaaggtttt ccatccttat cagctcaagt cttacgtgaa cagtttattc taagacaaat
    18721 agaaaacaag gtcgatttgt acgaaattgc aaaaaaatta ggattaaaaa cagtcctgac
    18781 cttagaaaaa tatagataat ggatattaaa ttaaaagatt ttgaaggacc cctggacttg
    18841 ctcttgcatc tggtttctaa gtaccagatg gatatctacg atgtgcccat tacggaagtc
    18901 atcgaacagt atctagccta tgtctcaacc ctgcaggcca tgcgtctgga agtgacgggt
    18961 gagtacatgg tcatggctag tcagctcatg ctgattaaga gtcgtaaact ccttccgaag
    19021 gtagcagaag tgacagactt gggggatgac ctggagcagg acctcctctc tcaaatcgaa
    19081 gaatatcgca agttcaagct cttgggtgag cacttggaag ccaagcacca agaacgggcc
    19141 cagtattatt ccaaagcgcc gacagagttg atttacgaag atgcggagct tgtgcatgac
    19201 aagacgacca ttgacctctt tttggctttt tcaaatatcc tagccaagaa aaaagaggag
    19261 tttgcacaaa atcacacgac gatcttgcgg gatgagtata agattgagga catgatgatt
    19321 atcgtgaaag agtccttgat tggacgagat caattgcgct tgcaggattt gttcaaggaa
    19381 gcccagaatg tccaagaggt catcaccctc tttttggcaa ccctagagtt aatcaaaacc
    19441 caggagctga tcctcgtgca agaggagagt tttggagata tctatctcat ggaaaagaag
    19501 gaagaaagtc aagtgcctca aagctagact tgatagagag gaaagatgag tactttagca
    19561 aaaatagaag cgctcttgtt tgtagcgggt gaagatggga ttcgggtccg ccagttagct
    19621 gaactcctct ctctgccacc gacaggcatc cagcaaagtt taggaaaatt agcccagaag
    19681 tatgaaaagg acccagattc cagtttggct ttgattgaga caagtggtgc ttatagattg
    19741 gtgaccaagc ctcaatttgc agagattttg aaggaatact ctaaggcgcc tatcaaccag
    19801 agcttgtctc gggctgccct tgagaccttg tccattattg cctacaaaca gccgattacg
    19861 cggatagaaa ttgatgccat ccgtggagtt aactcgagtg gagccttggc aaagttgcag
    19921 gcttttgacc tgataaagga agacgggaaa aaggaagtat tggggcgccc caacctctat
    19981 gtgactacgg attatttcct agattacatg gggataaacc atttagaaga attaccagtg
    20041 attgatgagc ttgagattca agcccaagaa agccaattat ttggtgaaag gatagaagaa
    20101 gatgagaatc aataagtata ttgcccacgc aggtgtggcc agtaggagaa aagcagaaga
    20161 gctgattaag caaggcttgg tgacggttaa cggccaagtg gtgcgtgaac tagcaaccac
    20221 tatcaagtca ggcgacaagg tcgaagttga aggtcaacct atctacaacg aagaaaaggt
    20281 ctactatctg cttaacaaac cacgcggtgt gatttccagt gtgacagatg ataagggtcg
    20341 caagacggtt gtcgacctct tgcccaatgt caaagagcgt atttaccctg tgggtcgttt
    20401 ggactgggat acatcaggtg tcttgatttt gaccaatgat ggggacttta cagacgagat
    20461 gattcaccct cgtaatgaga ttgacaaggt ttatgtcgcg cgtgttaaag gtgtggccaa
    20521 taaggacaat ctccgcccct tgacccgtgg tcttgagatt gatggtaaga aaaccaagcc
    20581 agctgtttat gaaattctca aagtggaccc agtcaaaaat cgctctgtgg tgcagttgac
    20641 catccatgaa gggcgtaacc atcaggttaa aaagatgttt gaagctgttg gtctccaagt
    20701 agataagttg tctcggactc gtttcggaca cctagacttg acaggactcc gtccaggaga
    20761 atcccgtcgt cttaataaaa aagaaatcag ccaactacac accatggctg taactaagaa
    20821 ataatgaaac gaattttaat agcgcctgtg cgcttttacc aacgttttat ctcaccagtc
    20881 tttccaccct cttgtcgctt tgagctgact tgttccaact acatgattca ggctattgaa
    20941 aaacatggtt ttaagggggt attgatgggc ttggctcgga ttttacgttg tcatccctgg
    21001 tcgaaaacag gtaaggaccc cgttccagac cacttttccc ttaaacgaaa tcaagaaggg
    21061 gaatgaggtg gggtaaatag atttcaaaat gataaaaacg catcctatca ggtttgagta
    21121 aacttgatag gatgcgtttt agaatgtcaa aattttatac tcttcgaaaa tctcttcaaa
    21181 ccgcgtcagc tttcatctgc aacctcaaaa cagtgttttg agcaacctgc ggctagtttc
    21241 ctagtttgct ctttgatttt cattgagtat taaattgagt ttgaagtggc ttatttcaaa
    21301 gctttttgta tgtcttcaat catgagtttt gttgattcaa gtccgcctcc gcttagatac
    21361 cagaggtctg gtgttagttg gataatctta ccatttttag cagcaggtgt ttcagcgata
    21421 agggcatttt ctaggacacc gtcgttgcta gagttgtccc caccgatggc aagggtacgg
    21481 ttgatgacaa agaggatgtc agggttgatt tctttgacac tttcaaagct gacttcttgt
    21541 ccgtggcgtg agtcttcaaa ttttgtatca gttggtttga atttcaaggt ttggtacaag
    21601 aaagagaaac gagatttggc accaaaggct gccatttttc cttcattaag gaggatcgca
    21661 agggcttttt tgtcagagct ttcattttta gtagcgactt cttggatgct cttgtctagc
    21721 ttggccaatt cttccttggc tttctgtgta ccagtttcgc cgaaggcact tgctaaggat
    21781 tcgatattag ccttggtaga agtccagtag tcgtccttgc ttgcttggaa gagaacggtt
    21841 ggggcgattt ctttgaattt gtctacgaat ttttgtgtac gtggtgaagc gataatcaaa
    21901 tcaggctcaa gggcggcgat agcttctaaa tcaggttctt tcatagaacc aacatttttg
    21961 acagttccca ctaggtcttt tagataagtc ggaacagttt ttgtaggcat tccgacgata
    22021 tttttttcaa atcctaaagc gcgaatagta tccgcagcgc cgaggtcaaa ggtcacaatc
    22081 ttttcaggaa ctttggaaag tttgacctcg gccagtgaac ttttaatggt tacctctgtt
    22141 ggagcagagc tactggtctc tgtctgacta gtgcttgagt ttgtactaca tgcaccaagt
    22201 aggagcaaga agctggccac tagggcagtg aaataaagtt taagggatgt tttcataatt
    22261 tctcctcttt aaaatgtgat aacgatttag ggagtctctt gatcttattg actaagagac
    22321 tgaaggttct ctaacttgag cttttatgtt actagctata gatacagatc tttttgtcat
    22381 tgatatcagc tagcgtgatg ggaatctcat aaagttgact gagcaggtca gcctgcatga
    22441 tttgatcggt tcttcccttg ctaaagacct ggccgtcctt gaaggcgaca atttcatctg
    22501 catactgact ggctatgttg atatcgtgga ggacgatgat aatggtcttg ccgagttcct
    22561 ccaccagtcg tcgaagaatc tgcatcatgc tgacgctttg cttgatatcg agattgttga
    22621 gtggttcgtc cagcaagata aagtccgtat cctgggccag taccatagcg ataaagacgc
    22681 gctggagttg cccccctgac aggctattga tgtagcggtc ttttaagttg gtcagttcca
    22741 aatagttcag agtttctcgg attttttccc agtcttctga tctaagtcga cctcggctgt
    22801 agggaaaacg tccaaaactg accagttctt caacagtcaa tttggcttgg taattgattt
    22861 tctgttttag gatggttagt tcttgggcca gttcttgcga attccagctc tcgatttcac
    22921 gtcctttgat actgagaact ccctgatctt tcttggttag tctgctcatg atggagagga
    22981 gagtcgattt tccagcacca tttggaccaa taaaggctgt cagtttttga ggactgactt
    23041 caagcgaaat gccttgcaaa atatcctgtt tttgaatgga tttgtcaatg ttttccagtt
    23101 tcactgacga gccctcctat atagtaagat aaagaataag aagccaccca cactctcaat
    23161 gatcatactg atacgaattt ccagtgcaaa gactcgttca atcaaggctt gccccaaggt
    23221 taagctaata aatccaacca gaatggccac tataaagagt aacttgtgct gatagtcttt
    23281 gacaatcagg taggtgaggt tggccagcat aaagccgaag aaggccatag gtcctaccaa
    23341 ggcagtggcc gttgaggtca aaagcacgat tccccagagg agctctttct gttctttttc
    23401 aacatcgagt cccaatatct gagccgtttc tctttgcagg tgcaagacat ctagaacgac
    23461 tgcttttcga aagaaaaaga ttgtcaaagc gaggatgatc agagaaccga tggctaggat
    23521 ggaagtgttg agatgttgaa aggaggcaaa aagactattt tgcagtttat cgtattcgtt
    23581 tggatccatt aggacttgaa ggaaggtgct gatatttcga aagagacttc tgagcgctag
    23641 acagatcagc aggatgaaga ccaggtcttg cttcatcagt gtcttcaagt aaccttgtaa
    23701 ggcgagaaag aagagggact ggacaagaag taagactagg aattctaaga taggggattt
    23761 gccaagttga agaaacttgc tttcaaaaac cagtagtagg gtttgtagta ggacgtagaa
    23821 ggattcaatt cccaaaatac taggcgtcag gaagcgattt tccgtcaggg tttgaaaact
    23881 aatggtcgaa atcccagtcg cgatggctac caagagataa acgatgatct tttgggaacg
    23941 caacttccaa gcaaaggctg acaagtgagt gatgggccaa aagtagagaa gacaagctcc
    24001 gatggcaaga ataatgagaa tccagaagag cttggtatgt ttgcttttag tctgcatctt
    24061 ttcgtccccc tctccagaga agtaggataa agacgagact accgatgatt cctagcaaga
    24121 gactgacaga caactcatag ggcctaatca gaactcggga taggatatcg caagccagaa
    24181 ctagattggc accaaccagt gcgaccatga gtttggtttg acttagatta tctccatagc
    24241 gcttgcgaac aagattggga acgataactc cgagaaatgg taggccaccc acggtaatca
    24301 tggtgacgct tgtcgttagc gccaccagaa agagggccag tttttcaagt agggagtagg
    24361 aaatccccaa actctcgctg gtttctttcc ctagattcat gatggtgaag gtttgggata
    24421 atttccaaac ggttatcagg atgatgaggc ctaagaagag ccactcatac tgatgggtct
    24481 gaatcatgga gaaggagccc tgggtccagg cagtcatact ctgaaccaga ttgaaacgat
    24541 aggcgataac ttctgtgact gagccgataa tcccgctata gatgatccca atcagaggca
    24601 acatccacct ttcctttaca gtaaaaatgg tcataaaggc taggaagaag agggtgaata
    24661 cgatggatga aacaaaagcg aagagcatct tttgggtcag actagccgat ggaaagacaa
    24721 aaaggctcag caccattccc agtttggcgg cttcagtcgt tccaactgta ctcggtgcag
    24781 caaactgatt ttgggtaata gtctgcatga gaaggcctgc catactcata ctagaggcag
    24841 tcaggagaat actgatagtt cttgggagac gggactcttg aaagaggagc caggtctgct
    24901 ggtcgaaatc aaatagcttt ccccatgaaa aatcactggt cccaatgcta atagagagaa
    24961 agactaggag tagaagtaag ccaattaaat aatgagaaag tttcataccc cgtcctttca
    25021 tgtagatttg gtatcgaaag atatctgcgg atataaatgt aacattattt ttctaatctg
    25081 tcaataaaat ttctgacaat ttaataaata caacaaggag agagcaacaa gactttctcc
    25141 tttgttatcc tattctaaaa tgtttttacc ttaatctgat aaaataatat cttcgaggga
    25201 gtagctagcc gtccaatcaa gatattgttt agcttttgaa gcatctgcta ggacactggc
    25261 tgggtcacta gcacgtcgag caacaatctc gtgtgggatt ttttaattta gtaattcttc
    25321 agcagtttta aagatttctt tgatagtata gcctttttta gttcctaagt taaagatttg
    25381 agaagaactg tcttcttgaa ataggtagtt cattccttta acatgagcct atgcaaggtc
    25441 caagacataa atgtaatctc gaatacatga accgtcacgt gtatcgtagt catctccaaa
    25501 tatttttaag ctatcatttt gtcccaatgc ggtcttgttg atatttggaa tgatgtgagt
    25561 tggatttttc acacgcagac cgtttgaagc atccatttca gccccagcaa cattaaagta
    25621 acggaaaata acatatttcc agtcgtagcg attggccatc cagtaaatca ttcgttcgcc
    25681 catcagtttt gtctctgcat aagggttgac agggtcgagc agggtatctt cagtcaccgg
    25741 cttgtcaata cagttatttc catagagaga agcagtcgaa gagaacatga ttttttgaat
    25801 gccaacttca gataagactt tgagaacttg gttcatacca gcaacgttgg cagtgaagta
    25861 tttacttgga ttttcaatac tttcgctcac aacaatttca cctgcacaat ggaggacagc
    25921 atcaatctga ttttcttcta agtaagcctt taaggcgcta gcatcataaa catccagttc
    25981 tttaaagcta gcacgactat ccacagccgc tcgatttcct gtggagagat tatcgaggac
    26041 atgcacctta tagccagcat ttaaaagagc tttaacggta tgggagccaa tgtagctagt
    26101 cccacctgta acaagaattg ttttggtcat gattttttcc ttttctagtt ttgtactata
    26161 gtaaattgaa ataagatatg aacaactcta ttaggaaagt caaattaatt tctagaaatg
    26221 tttcagcagc tacagcgtac tattccaaac tcaaccaact atatatttaa agaaagaaga
    26281 aagggaagtc aactattttc tgtaaatttc atgaaaaatc caaacaactt tgatggtgta
    26341 ttgttttttt gtttggaaat aaatattcga gttaattttg gaatgtttac tagattttgc
    26401 actacatgca agagaatact atccttttct aagatagagc aggactaaga tactaactta
    26461 gaaatccacc ttcccactat ccttctccta taaaaagtgg taaaatggat gaaagaaaga
    26521 aggaactgaa atgacaacat tattttcaaa aattaaagaa gtaacagaac ttgctgcagt
    26581 ctcaggtcat gaagcgcctg tccgtgctta tcttcgtgaa aagttgacac cgcatgtgga
    26641 tgaagtggtg acagatggct tgggtggtat ttttggtatc aaacattcag aagctgtgga
    26701 tgcaccgcgc gtcttggtcg cttctcatat ggacgaagtt ggttttatgg tcagcgaaat
    26761 caagccagat ggtaccttcc gtgtcgtaga aatcggtggc tggaacccca tggtggttag
    26821 cagccaacgt ttcaaactct tgactcgtga tggtcatgaa attcctgtga tttcaggttc
    26881 tgttcctccg catttgactc gtggaaaggg gggaccaacc atgccagcca ttgccgatat
    26941 cgtttttgat ggtggttttg cggacaaggc tgaggcagaa agttttggca tccgtcctgg
    27001 tgataccatc gtaccagata gttctgcaat tttgacagcc aatgaaaaaa atatcatctc
    27061 aaaagcttgg gataaccgct acggtgtcct catggtaagc gagctagctg aagctttatc
    27121 aggtcaaaaa ctcggcaatg aactctatct gggttctaac gtccaagaag aagttggtct
    27181 gcgtggcgct catacctcta caaccaagtt tgacccagaa gtcttcctcg cagttgattg
    27241 ctcaccagca ggtgatgtct acggtggtca aggcaagatt ggagatggaa ccttgattcg
    27301 tttctatgat ccaggtcact tgcttctccc agggatgaag gatttccttt tgacaacggc
    27361 tgaagaagct ggtatcaagt accaatacta ctgtggtaaa ggcggaacag atgcaggtgc
    27421 agctcatctg aaaaatggtg gtgtcccatc aacaactatc ggtgtctgcg ctcgttatat
    27481 ccattctcac caaaccctct atgcaatgga tgacttccta gaagcgcaag ctttcttaca
    27541 agccttggtg aagaaattgg atcgttcaac ggttgatttg attaaacatt attaaaccat
    27601 aagggaggtg gtagggatgg tagaaccaaa cctagaaagc cttataaaag atctttacaa
    27661 tcatgctcga catgatttga gtgaagattt agttgctgct ctcctagaga ctactaaaaa
    27721 actgcctact acaaatgagc aattgcaggc agttcgtctc tcaagcctgg tcaatcgtga
    27781 attgctccta aatcccaaac atccagcacc tgagttgctc aacttggctc gctttgtcaa
    27841 aagagaagaa gccaagtaca gaggaactgc gacttctgcg cttatgtatg aggaactttt
    27901 taaaatgctt tgattccatt gtggatcaaa gcatttttta taagacctat ctcgtgagcg
    27961 ttcaaatagt agtaacaagg aatcatgaga agtcagccga gaccatagta gtgaagaaac
    28021 ttctgtaatg gaagtggagt gaagtgagga atcatcaaac ggtaggggat aggctgtttg
    28081 aagggtgcta cgaaaaagat agggtaaggt gaaattatag cggaatgaaa taagatatga
    28141 acaaattgat tagggaaatc aaatgaattt atagaaatct tttagcagtc atggcgtcct
    28201 attctagttt caaaatgcta taaatacgaa caaattgatt gggaaattca aatcgctttc
    28261 tatcaatgtt ttagaagata cagtgcccta gtccaacttc aatatactat aaaagaacag
    28321 atggaagcaa ttatgattta cttctatctt taaaataaat gatctgatag gaaaaatgtg
    28381 tcccctcata aaaaatagga tagtacggat ggaaggcttt tgtagactgg aggacgaagg
    28441 aatttagaaa ctctcgttaa aagttagttg agccggagta tggtggtgtg aataattatc
    28501 aaaaattatt tccaaatcga aatagttgac agttagaacg atgagtgtta caattatttt
    28561 attcatttcg atatcgaaat aaattggagg tgttatgaaa gatagtcatt tgctagccca
    28621 tcatattcgt ttgttgaatg ggcggatttt tcaaaagtta ctgagtcaag atcctgaggc
    28681 tctttatagg ggtgaacagg gcaagatttt agcggtttta tggaatagtg aaactggctg
    28741 cgcaactgcg acagatatcg cgcttgcgac tgggcttgcg aataatacgc tgacgactat
    28801 gataaaaaag ctagaggaac aaaagcttgt aattgttagt ccgtgtggaa aagacaagcg
    28861 taagaagtat ttagttttaa cggagttagg caagttccag aaagaagtgg ggcatcgtgt
    28921 cagtcagaaa ttggatacta tcttttacaa aggattttca gaggaagaaa ttcaccaatt
    28981 tgaaggtttt caagaaagaa ttttggcaaa tctgaaagag aaggaaaatg aggtttagaa
    29041 tatgtcacaa caagtgaaaa atgctcacaa cctatacatc catgccattc aagacggacg
    29101 agttgctgag gctcaagccc agtctgtagg ggatacctat atccaacatt cgacaggtgt
    29161 tcctgacggg aaagaaggat ttgcagcctt ctttgcagat ttctttgagc gtcatccaga
    29221 gcgtcagatt aagattgtcc gcaccattga ggatggcaat ctggtctttg ttcatgttca
    29281 tcaatatctg aatggtggag aagctcaatg ggtgacgacg gatactttcc gtgcggatga
    29341 gaatggtcgt attgttgagc attgggatgt cattgactac tatcgaacac ctgaaaatga
    29401 ccaactagat caaatttttg gagattttga aatcaaggat ttggacaaga aagcagaaaa
    29461 taaaaagctg gttcgccgtt tcttgacaga aactttccaa aatggggagc tagagcagtg
    29521 gagtgattat gtggcagacg atttgattca gcataatcat gagattggac aaggaagtgc
    29581 tgcttataaa aactatgtgg ctgaatatag tgtcactttt gactttgttt tccaactctt
    29641 aggacaagga aactatgtgg ttagctatgg tcagactcag attgatggcg ttgcttatgc
    29701 ccagtacgat atcttccgtt tagagaacgg gaaaattgtg gagcattggg ataataagga
    29761 agtcatacct aaggtagaag acttgactaa tcgagggaag ttttaaattg aggacaaaga
    29821 atgattgaat acaaaaatgt agcactgcgc tacacagaaa aagatgtctt gagagatgtc
    29881 aatttacaga ttgagaatgg ggagttcatg gttttagttg ggccttctgg gtcaggtaag
    29941 acgaccatga ttaagatgat taaccgtctc ttggaaccaa ctgatggaaa tatttatatg
    30001 gatggcaagc gcatcaaaga ctatgatgag cgtgaacttc gtcttactac tggatatgtt
    30061 ttacaggcta ttgctctctt tcccaatcta acagttgagg aaaatattgc tctcattcct
    30121 gaaatgaagg gttggactaa ggaagaaatt gctcaaaaaa cagaagagct tttggcaaaa
    30181 gttggattac cagtagctga gtatgggcat cgacttccaa gtgagctatc tggtggagaa
    30241 cagcaacggg tcggtattgt ccgagctatg attggtcagc ccaagatttt cctcatggat
    30301 gaaccctttt cggccttgga tgctatttcg agaaaacagt tgcaggttct gacaaaagaa
    30361 ttgcataaag agtttgggat gacaacgatt tttgtaaccc atgatacgga tgaagccttg
    30421 aagttggcgg accgtattgc tgtcttgcag gatggagaaa ttcgccaggt agcgaatccc
    30481 gagacaattt taaaagtgcc tgcaacagac tttgtagcag acttgtttgg aggtagtgtt
    30541 catgactaat ttaattgcaa cttttcagga tcgttttagt gattggttga cagccctatc
    30601 tcaacatttg cagttgtcac ttttgacctt gttactagct attttgcttg cgattccctt
    30661 ggctgtttat cttcgctatc atgagaagtt ggcggattgg gtcttacaga ttgcagggat
    30721 tttccagacc atcccgtctc tggccttgtt gggactcttt attcccttga tgggaattgg
    30781 gactttaccg gcattgacag ctctagtgat ttatgcgatt tttccgattt tacaaaatac
    30841 tattactggg ctgaagggaa ttgatccgag tcttcaagag gctgggattg cctttgggat
    30901 gaccagatgg gagcgtctca agaagtttga aattccactt gccatgcctg ttatcatgtc
    30961 tggaattcgg acggcagcgg tcttgattat cggtacggct accttggcga ccttgattgg
    31021 ggcaggggga ctgggttcct ttatcctgtt gggaattgac cgtaataatg ccagtttgat
    31081 tttgattggg gccctttctt ctgcagtgct agctattgcc tttaacttcc tactaaaagt
    31141 aatggaaaaa gcgaaattgc ggacgatttt ctctggtttt gccttggtgg ctttattact
    31201 gggtctgtct tatagtccag cccttttggc tcaaaaagag aaggaaaact tgattattgc
    31261 tgggaaaata ggcccagaac cagaaatttt ggctaatatg tataaattgc tgattgaaga
    31321 aaataccagc atgactgcga ctgttaaacc gaattttggg acgacaagtt tcctttatga
    31381 agctctgaaa aaaggtgata ttgacattta tcctgaattt accggtacgg tgactgaaag
    31441 tttgcttcaa ccatcaccca aggtgagtca tgagccagag caggtttatc aagtggcgcg
    31501 tgatggcatt gccaagcagg atcatctagc ctatctcaaa cctatgtctt atcaaaatac
    31561 ctatgctgta gctgttccga aaaagattgc tcaagaatat ggcttgaaga ccatttcgga
    31621 tttgaaaaaa gtggaagggc agctgaaggc aggctttacg cttgagttta acgaccgtga
    31681 agatggaaat aagggcttgc aatcaatgta tggtctcaat ctcaatgtgg cgactatgca
    31741 gccagctctt cgttatcagg caattcagtc aggggatatt caaatcacgg atgcctattc
    31801 gactgatgcg gaattggagc gttatgattt acaggtcttg gaagatgaca agcaactctt
    31861 cccaccttat caaggggctc cactcatgaa agaagctctt ctcaagaaac acccagagtt
    31921 ggaaagagtt cttaatacat tggctggtaa gattacagaa agccagatga gccagctcaa
    31981 ctaccaagtc ggtgttgaag gcaagtcagc aaagcaagta gccaaggagt ttctccaaga
    32041 acaaggtttg ttgaagaaat gatgggacag agactttaaa catactgaac tcaacttcct
    32101 taaacgacta gataaaagaa tgctcagaca atttcgtctg ggcttttttg atgtgagaat
    32161 gactgaatgt cacttaaaat ggaaagaaag agaaaatttt catgattttc taaaatttta
    32221 ctgtaaagac agttgactat tcataaaata ggtgtataat attttgtgaa ctacttaaca
    32281 aataagaggt ttcagctcat gtcgactaag gttagaaatc ttgtgtatag gcagttcatt
    32341 atctaataga gcgttgcgtc cgaaagtcta tccagacacg gctctttaaa aacaaaagga
    32401 gaaatgatgc atacttattt gcaaaagaaa attgaaaata tcaaaacaac cctaggtgaa
    32461 atgtcaggtg gttaccgtcg tatggttgcg gctatggctg atttaggatt ttcaggaact
    32521 atgaaggcta tctgggatga cctctttgcc catcgtagtt ttgcccagtg gatttatttg
    32581 ctggttttag gaagttttcc tctctggctg gagttggttt acgaacatcg tattgttgac
    32641 tggattggga tgatttgtag cttgacaggg attatctgtg taatctttgt atcggaaggt
    32701 cgagcaagta attatctttt tggcttgatt aactctgtta tttaccttat tttggcccta
    32761 cagaaaggct tttatggtga ggtgctgacg acactttact tcacagtcat gcagccaatt
    32821 ggacttctag tttggattta tcaggcacag tttaagaagg aaaagcagga gtttgtcgcg
    32881 cgtaaactgg acggcaaggg ctggacaaag tatctttcca ttagtgtgct ttggtggttg
    32941 gcctttggct tcatttatca gtctattggt gccaatcgtc cctatcgtga ttcaatcaca
    33001 gatgcaacca atggggtagg gcaaatcctc atgacagctg tttaccgtga acagtggata
    33061 ttctgggcgg ctaccaatgt tttttcaatc tatctctggt ggggagaaag cctgcaaatt
    33121 caagggaaat atctaattta tctcattaac agtctagttg gttggtatca atggagcaag
    33181 gcagctaagc agaatactga tttacttaac taggaaaaga tgtttgaaag tgctgttttg
    33241 agatttcgat taaaacagat atagttgata atcaaggatt tatagtatga aaaagaggat
    33301 cggcgggtcc tcttttgttg ttgaaaagat aaaaaactca gtaacctaga aataagacaa
    33361 ctgagcttta ctctatattc aatttttagg aatgagaagg tctagataaa attggacaac
    33421 ttcctggcct gtgaaatctt gacctttttt gagccaccag gtcaatgtct cgataaagtt
    33481 ggacacgacc aagtgttgga ggtaagaagt aggcatatta gggtgggctt cttttaaatt
    33541 atcagctagc acggaataga catggtgttc tagctcttta tggagttgac ggaggaagta
    33601 gtcatttttg gaaaatagca gactggtgat atggtcttgg tttttatgaa aatggagaaa
    33661 gaggtgggcg aggtagtcct cggttgaaat ggcttgctct ctttcaaaaa gatgatggaa
    33721 gaggtagcgg cagagctggt ccagaagaag ctccttactt tcatagtgac agtaaaaggt
    33781 ggatcttccc acatctgcga gatcaatgat atcctgaaca gtagtggcct cgtagccctt
    33841 agcattcaaa agttgtataa aagcttgata gatggctttt ttggttttgc tgatacggcg
    33901 gtcaatgtta gtcatatgga cacttaaggc aaattgttca gaactgaata aagctgacgt
    33961 tttgcttcta tcctttcttt gagttttagt ggataatgat aatgaacaag gtgttcataa
    34021 atctattata acaaaggaat gagaaatatg aaggcaaaat atgctgtttg ggtggctttt
    34081 ttcttaaatt tgacttatgc cattgttgag tttattgcag gtggagtatt tggttctagc
    34141 gctgttcttg ctgactctgt gcatgacttg ggagatgcga ttgcaattgg aatatcagct
    34201 tttctagaaa caatctccaa tcgtgaagaa gacaatcagt acaccttggg ctataagcgg
    34261 tttagcctgc taggagcctt ggtaacagct gtgattctcg taacgggctc tgttctagtc
    34321 attttggaaa atgtcacgaa gattttgcat ccgcaaccag tcaatgatga ggggattctc
    34381 tggttaggaa ttattgcgat tactatcaat ctgttagcga gtctggtggt tggtaaggga
    34441 aagacaaaga atgagtctat tctgagtttg cattttctgg aagatacgct agggtgggta
    34501 gctgttatcc tgatggcgat tgttcttcga tttacggact ggtatatcct agatcctctt
    34561 ttgtcccttg tcatttcttt ctttattctt tcaaaagccc ttccacgttt ttggtctaca
    34621 ctcaagattt tcttggatgc tgtgccagaa ggtcttgata tcaagcaagt aaagagtggc
    34681 ctggagcgat tggacaatgt ggccagcctt aatcagctta atctctggac tatggatgct
    34741 ttggaaaaaa atgccattgt ccatgtttgt ctaaaagaaa tggaacatat ggaaacttgt
    34801 aaagagtcta ttcgaatttt cctaaaagat tgtggttttc aaaatattac cattgaaatt
    34861 gatgctgacc tagaaactca ccaaacccat aagcgaaagg tgtgtgactt ggaacggagt
    34921 tatgagcatc aacattagaa aaaagtgaaa aatacttggg tactatctta tttggaatag
    34981 agtaatttct ttattattta aatatttcaa aaattggtaa gagaagagca ttgtataaac
    35041 tccggatata tgattgttaa tgataaaaat ttttcgatta gatacaaaat gcttgacttg
    35101 gagtcaactc aaagttatat aataagataa gtgagttaga atagcgtgaa ttcagtgaat
    35161 gaaatgagag gaggttagcg tgtgaatatt aaatctgcca gtgatttgtt gggaatttca
    35221 gcggatacga ttcggtatta tgaacgggtt ggtcttgtgc caccgattac tcgtactgct
    35281 actgggattc gtgattttca agatcaggat atcgaagcgc tggaatttat taagtgtttt
    35341 cgttcggcgg gtgtctctgt agatagttta gttgactata tgtcgctcta ccaaaaggga
    35401 gatgaaacga gagaggagag gcttggtatt ttagaagagg aaaagcaaaa attagaggag
    35461 cgcttgtctc agctacagac agctttaaat cgtttaaatc tcaaaattaa actttataag
    35521 gaaggaaaat tttaaatgaa atcagcagta tatacaaagg caggtcaggt tggacttgct
    35581 agcattgaac gtccgcaaat aatagaagcg gatgatgtga ttattcgtgt ggttcgtgcg
    35641 tgcgtttgtg gttcagattt atggaggtac cgtaatccag aaacgaaagc tggacataaa
    35701 aatagtggac acgaagcgat tgggattgtt gaagaagctg gggaagccat tacgacggtg
    35761 aaaccaggtg attttgtgat tgtccctttt acacatggat gtggtgagtg tgatgcctgt
    35821 cttgctggat ttgacggttc ttgcgacaat catattggca ataatttggg gggtgatttt
    35881 caggcagaat atattcgctt ccactatgca aactgggcgc tggttaaaat ccctggtcaa
    35941 ccttctgatt atacagaagg gatgctcaag tcccttttga ctcttgcaga tgtcatgccg
    36001 acaggctatc atgcagcgcg tgttgcaaat gttcaaaaag gggacaaggt tgttgttatc
    36061 ggtgatgggg ctgttggtca atgtgctgtc atcgcggcta agatgcgtgg agcatcacaa
    36121 attatcctta tgagccgtca tgaagaccgt caaaagatgg ctatggagtc aggtgcgaca
    36181 gctgttgttg cagaacgtgg tcaagaagga attaccaagg tgcgtgaaat cctcggtgga
    36241 ggagcagatg cagcacttga atgtgttggt acggaggctg ctatagaaca ggcgctaggt
    36301 gttcttcata atggagggcg tatgggcttt gtaggagtcc cacactataa taatcgtgct
    36361 cttggttcga catttatgca aaatatctct gtagcaggtg gggcagcttc tgctacaaca
    36421 tacgataagc aatttttact aaaagccgtc cttgatggtg atatcaatcc aggtcgcgtc
    36481 tttacttcaa gttataaact ggaagatatc gaccaagcct acaaagatat ggatgaacgt
    36541 aagaccatta agtctatgat tataatcgaa taaaaaacga ataggagttc taaaactcct
    36601 attcgttttt tatgttatcc tattcttgat ttagggtact ttctcttaat gtcagtctgg
    36661 ttcccagcat ggtcaggcta gggattttcc gaccgtggag gacttccttg ttaagaatat
    36721 ccatacctgc tcggcccatt tcttcagtat aaactgtaat actagagagg ggaggataga
    36781 cctgtttggt cagactagtg tcgttaaagg aaatgaggct gacgcgatct ggcaggttga
    36841 ttccagcttc ttggagggca cggagggcac cgatagctaa actatcgctg gctgcgaaaa
    36901 atgctggcgg aagttggtct cccaagctct gaatggcctc cttcatcaag tcatagccag
    36961 actgggcagt aaagtttcct tgaaagatca gttcatcatg atagattcct tttgcttgac
    37021 tgtagtttct gaaattttcc agccgcttat cctcaatgat ttcttcttgg tctgttgttt
    37081 cttcaaggcc tgttagaatc ccgatacggt ccattccttg actgaggaaa taatcgacaa
    37141 cctgtttcat agcagtgtaa aaatccgtga taatacaggt atgtcccagg gaaagtgtat
    37201 cgctgtctag aaatacaaga ggcttttggt attcttcaaa ggcagaaatc tgagctcgac
    37261 taaactttcc gatgcagaga atcccaatca cttcctcgct tagggtaaaa gggtggtcat
    37321 taaaatagcg caagatatcg tagtccaact cttgggctct tttttctatt cctaggcgaa
    37381 tctggtagta gtagaggtcg tctagctccc cttgttcgct gacccattga ataatggcaa
    37441 tcttttgctt gggtttgtgg gactcgcctg tcttgaggtg cttggtgtag cccagctctt
    37501 cagcaacggt taaaatacgg tgtctggttt cttctgtaac agataggctc tggtcgcggt
    37561 tgaggacacg ggatacggtc gcgattgaga cagaggctag ctgtgcaatg tcttttaagg
    37621 tagccataaa tcctccttga ttaggttagt atatcatatt tttcttcttt ttactgatat
    37681 tttagtaaaa ttttagtaaa aaggattgac cttgggaaat tccttggata caatagaaag
    37741 aaaacgatta cacgttaaga tggcttaacg gacagtcaaa ggagaattca tatggcacaa
    37801 catcttacta ctgaagtcct tcgcaaagac tttcttgctg tttttggtca agaagcagac
    37861 caaaccttct tttcaccagg ccgtattaat ttgattggtg aacacacaga ctacaacggt
    37921 gggcacgttt ttcctgctgc tatttccttg ggaacttacg gtgcagctcg taagcgtgac
    37981 gaccaagtct tgcgtttcta ctcagctaac tttgaggaca agggcattat cgaagtgcct
    38041 ctcgctgacc tcaagtttga aaaagagcac aactggacca attatccaaa aggggttctt
    38101 catttcttgc aagaagctgg gcacgtgatt gacaaaggtt ttgattttta tgtttatggg
    38161 aatatcccaa atggtgctgg cttgtcttct tcagcatcct tggagctctt gacaggagtc
    38221 gtggcagagc atctctttga tttaaaacta gaccgtttgg atttggttaa aatcggaaaa
    38281 caaacagaaa acaactttat cggagtcaac tctggtatca tggaccagtt tgctattggt
    38341 atgggggctg accaacgtgc tatttactta gataccaata ctttagaata cgacttggtg
    38401 ccacttgatt tgaaggacaa tgtcgttgtt atcatgaaca ccaacaaacg ccgtgaattg
    38461 gcggactcta aatacaatga acgtcgtgct gagtgtgaaa aagcagtgga agaattgcaa
    38521 gttgccttgg atattcagac cctgggtgaa ttggacgagt gggccgttga ccaatatagc
    38581 tatttgatta aagatgaaaa tcgtttgaaa cgtgctcgcc atgctgtgct tgaaaaccaa
    38641 cgtaccctta aagctcaagc agcccttcaa gcaggtgatt tggaaacatt tggtcgtttg
    38701 atgaatgcgt cacacgtttc tctggagcat gattatgaag taactggttt ggaattggat
    38761 actcttgttc acacagcttg ggcacaagaa ggagttctcg gtgctcgtat gacaggggct
    38821 ggttttggtg gctgtgccat tgccttggtt caaaaagata ctgttgaggc ctttaaggaa
    38881 gctgtaggca aacactacga ggaagtagtt ggatacgctc caagcttcta tatcgctgaa
    38941 gttgcaggtg gcactcgcgt ccttgactag tcaaaaggag gctctatagt gatcttagta
    39001 gataaatttg taacacatgt catttctgaa agttcatttg aggaaatgga tcgaatctac
    39061 ctgaccaacc gtgttttggc acgagtggga gaaggtgttt tggaagttga gaccaatctg
    39121 gataaattga ttgacctcaa ggaccagcta gttgaggaag ccgttcgatt agagatgatt
    39181 gaggatagtc agactgcgcg tgaaatcctt ggtactgaac tgatggactt ggtgactcct
    39241 tatccgagtc aggtcaatcg tgacttctgg gaagcctatg tccactctcc tgagcaagcg
    39301 atagaggatt tttatcaact cagtcagaaa aatgattaca tcaaactcaa ggccattgct
    39361 aaaaatatcg cttatcgtgt tccatctgat tatggagaac ttgaaattac catcaatctc
    39421 tctaagcctg aaaaggatcc gaaagagatt gcggtagcca agttggtgca agctagtaat
    39481 tatcctcagt gtcaactttg tttagagaat gagggttacc atggtcgggt caaccaccca
    39541 gctcgcagca accaccggat tatccgtttt gaaatggttg gtcaggaatg ggggttccag
    39601 tattcgccct atgcttactt taatgagcat tgtatctttt tagatggcca gcatcgtccc
    39661 atggccatta gtcgtcagag ttttgaacgt ctgttggcta tcgtagagca gtttccagga
    39721 tattttgctg gatctaatgc cgacctgccg attgtggggg gctctattct aactcatgat
    39781 cattatcagg gaggccgtca cgtatttcct atggaattgg ctcccttgca aaagaccttc
    39841 cgatttgctg gttttgagca ggtcaaggct ggaattatca agtggccaat gtctgtccta
    39901 cgcttgactt cggattccaa agaggatttg attaacttag ctgataagat tttccaggaa
    39961 tggcgtcagt attcagattc tagtgtgcag attttagcag agacagacgg gacaccgcat
    40021 cacaccatca caccaatagc gcgtaagcgt gatggacagt ttgagttgga cttggtcttg
    40081 cgagacaatc agacttcagc agagcatcct gatggcatct atcatcccca caaggatgtc
    40141 caacatatca agaaggaaaa tatcggcttg attgaggtca tgggcttggc aatcttgcca
    40201 ccacgtctga aagaagaagt agagcaagtc gctagctatc ttgtaggaga agctgttaca
    40261 gttgccgatt atcatcagga gtgggcagac caactcaaat cccaacatcc agacctaacg
    40321 gataaagaaa aagcccttgc aatcgtcaag gactctgtgg gtgctatctt tgtgcgtgta
    40381 cttgaggatg caggagtcta caagcagaca gaacaagggc agacagcctt tatgcgcttt
    40441 gtggaacagg tcggaatttt actagactag gagctttctc cttgcacagt cctataaaaa
    40501 gtagtatcat agtgtcgttt gaaatatcag gaggaaacga tgaaagactt tcattttgac
    40561 gctatatctg cctttgaaag ttacgaaatt gaaaaaatga gagatggtca cgttgtggtg
    40621 acgaccaaag tagtgaactc atcgctcaac tactatggca atgcccatgg tggctatcta
    40681 ttcacgctat gtgaccaaat cagtggtttg gtggttatct cgctgggact tgatggggtg
    40741 acactccaat cctctatcaa ctaccttaag gcaggaaaac tcgacgatgt attgaccatt
    40801 aaaggagaat gtgtccatca aggtcgtaca acctgtgtga tggatgtgga tatcaccaat
    40861 caagagggca gaaatgtctg taaggcaacc tttaccatgt ttgtcacagg ccaaaggtct
    40921 gaggaaagac gggtaagtat ataaagaaag gtgagtggga taaatttatc tcactcattt
    40981 ttaatttatg agatatgtta gaaggaaata taaaagagag tgatgaaata caaatgtaat
    41041 aggtacatat atgtggtata ctagttatag tagattttaa ttgcttatat cgagtgagtt
    41101 ctcatattag tgaggaattt ttaaatggaa ttacacttta atttagaatt agtagaaacc
    41161 tataaaagta atagccaaaa ggcacgtatc ttaacggagg attgggttta tcgtcagtct
    41221 tattgcccta attgtgggaa caatccctta aatcattttg aaaataatcg gcctgtagca
    41281 gatttttact gtaatcattg tagtgaggag tttgaactaa agagcaaaaa aggaaatttt
    41341 tcatcaacaa tcaatgatgg tgcttatgca acgatgatga agcgtgtgca ggcagataat
    41401 aatcctaatt tctttttttt aacttacaca aaaaattttg aggtaaataa ctttcttgtc
    41461 cttccgaagc aatttgttac accgaaatcg attattcaaa gaaaaccact tgcaccaact
    41521 gctagacgag caggttggat tggttgtaac attgatttat cacaagtacc ttctaaagga
    41581 aggatatttc ttgtgcaaga tggacaagtt agagatccag aaaaagttac aaaagaattt
    41641 aagcaaggtt tatttttaag gaagagctct ctgtcatcaa gaggttggac aatagaaatt
    41701 ctaaattgta tagataagat agagggttca gaatttaccc ttgaagatat gtatcgtttt
    41761 gaaagtgacc taaaaaatat ctttgttaag aacaatcata tcaaagaaaa gattaggcaa
    41821 cagcttcaaa tattaagaga caaagaaata atagaattta aaggtagagg aaagtatcgg
    41881 aaattatgaa aacgaaacaa cttgttgcat cagaagaggt gtatgatttc ttaaaagtca
    41941 tctggcctga ttatgaaact gaaagccgtt acgataacct aagtttaatc gtctgtacct
    42001 tatcagatcc cgattgtgtg agatggttat ctgaaaatat gaaatttggt gacgaaaaac
    42061 aactagcttt gatgaaggaa aaatatgggt gggaagtagg agataaattg ccagagtggc
    42121 tacatagctc ctatcataga ttattgttaa taggtgaatt attggaaagc aatctaaaac
    42181 tgaaaaagta tacagtagaa attacagaaa ctttatcacg tttagtaagt atagaggctg
    42241 aaaatccaga tgaagccgaa cgacttgtaa gagaaaagta taagagttgt gaaattgttc
    42301 ttgatgcaga tgattttcag gactatgaca ctagcatata tgaataggta gatgttttta
    42361 ttttgtcaca caaaaaagag gctcgcacct ctttttctta tttcttttta tgatttaata
    42421 cggcattgag gacaatagcg agtaggctgg ctacgacgat tccgtttgag aagaacattt
    42481 ggaaggctgt cggcatgctg acaaagagat tactgttgtt gagaccgaca cctgcagcga
    42541 ttgaaacagc tgcgataagg aagttgtgtt cattgttagc aaagtcaact cgggcgagga
    42601 tttgcatccc ttgaatagat acaaaaccaa acatcaccag catggcaccg ccgaggacgg
    42661 agcttggaat gatttgggca agggcaccaa acttaggaag cagtccaagg agaaccagga
    42721 aaccagctgc gtagtagatt ggcaggcgtt ttttgatgcc tgacaattta accaaaccaa
    42781 cgttttgtga aaatccggtg taagggaagg tgttaaagat tcctccgaga agtaccgcca
    42841 aaccttctgc gcggtaaccg ttgcgaaggc gcgtgctgtc gattggatct tttgtgatat
    42901 cagacaaggc tagataaaca ccagttgact caaccataga caccgttgcg atgatacaca
    42961 tcatgacaat agatgagatt tcaaaggttg gcatcccaaa gtagagtgga gttgggacat
    43021 ggacaagtgg agctaccgca acaggagaga agtccaccaa gcccatagta gcagcaatgg
    43081 cagttccaac aaccagacca atcaaaatag agatagactt gataaatcct ttggtaaaga
    43141 tgttgatcaa gaggataatc agaacagtaa tagctgcaag caagagactt tgaccagttg
    43201 gctctggaac gttatttccc atatttccaa tagcgacagg gatcaaggtt aaaccaatcg
    43261 tggtaataac agatcctgtt acgatagatg ggaagagatt ggctactttt gagaagatgc
    43321 ctgaaacaag aaccacgtaa atcccagatg cgataagggc accaaacata gcgccattac
    43381 catggctttg cccaatcata atcaagggag cgaccgactg gaatgcaact ccaagaacga
    43441 ctgggagtcc aatcccaaag tatttgttga gttggagttg gaggaaggtt gccaccccac
    43501 acatgaagat atctgtagaa atcaggtagg tcaactgctc agctgaatag ccaagggctg
    43561 tcgcaatcat gatgggaacc aggatagatc ctgagtacat ggctagtaag tgctgcaagc
    43621 ccagaacggc tgcttgcgag tgtttttctt gagtttgcat tagagatctg cctccttaaa
    43681 tacgacctga ccattttcaa aacgatccaa gcgagcaagt gataggacag ggtagcctgc
    43741 tttttcaagc aaatcacgac catcttggaa ggatttctca atcacgatac cgatagcttg
    43801 gactgtggca ccggcctgtt cgatgatttg aatcaagcct ttagcagctt ggccattagc
    43861 aaggaaatcg tcgataatca aaaccttgtc ctctggtgag aggaattttc cagcgataga
    43921 aacagtgctg gtcacctgct tggtaaagga gtagacttga gcagttaaga tgccttcgtt
    43981 catggtgatg ttcttagctt ttttggcgaa aatcatggga acgtttaagg cttcagctgt
    44041 aaaaacggct ggggcaatac ccgacgcttc aatggttacg accttggtaa tgccagtagc
    44101 agcaaatttt tccgcaaaaa ccttaccaat ctctcgcatc aagctaaagt caacttggtg
    44161 ggttaaaaag gaatctacct tgaggatgtt atcacccaag atatgcccat ccttgaggat
    44221 gcgctcttct aataatttca taagacctcc taaagtctaa aagttaattt acttgttgtt
    44281 taaatatttc tatagtgatc ccttttgcta atactatata tttgataaaa ctattacgag
    44341 cgaagcgagt cttatcaaat atttcccgtt gtagtggtat catagacaat aatcttgtta
    44401 ttgtctatga cgggattttt gagagtaaaa tagttcgggg aactatttta gcctaagcct
    44461 agaaatgaaa gagctagggg ctcaaaaatt agggatgaaa ttccctggat tcctgaaatt
    44521 attcacagga taatttcacc tcccgtccgc actaattaag ggaaatatta aaaatattca
    44581 aaaaagacct acttaatctc taagtaagtc ccctaaatag acatggcaaa aacggccata
    44641 tctcactgct gacttactta ttgttaggtg ttccggcacc ttgtagaaac gtcgtgccaa
    44701 ttcacgacat aaacaagtaa aacgatattc aattttaaat aggcttgagc caatgttttt
    44761 attttacact aaataacttt agaaatcaac tattttgtta gtgttttggt ttaaaaagcg
    44821 aacaaaaata agagagggtg aacaaaaact ccattgtaag ctaacattta tactaaatga
    44881 aaatcaaaga gcaaactagg aagctatcca caacctcaaa acactgtttt gaggttgtgg
    44941 atagaattga cagagtcagt atcatatacc tacggtaagg cgacgttgac gtggcttgaa
    45001 gagattttcg aagagtatta gaagattttt ccatcataaa aggcatacta tcaagttttt
    45061 agacacctga caatatgcct ttttctaact ttaaagactt ttcccaattt ttattattct
    45121 actcgctaaa tcttaaaaaa tagccatctg gatccaaaac tgcaaattta tgaggataga
    45181 tatagggatc actgacacga aactttcttt tggtcaagag acgataaata ggatagtttg
    45241 cctccatcac tttttgatag agttttggaa catcctttat gccaaaggag agattgactc
    45301 cacgaccaaa ggggtaggtc agttcagcta gttgatcctt tgttccctcc tctaacatta
    45361 gttgacactc ttcaagagaa agagaaagtt ttcttctgga cgttagtatt caatcctaaa
    45421 acccagtaaa ccacagtaga aggaccggga ctgttcgata ttcgatacaa gaaactcggg
    45481 aatgaccgca ttgtagtcca tatagaaaat ccttacaagt caatttccaa gacaatcggt
    45541 gtatggtctt ggcgagcacc tgagtcaatc atatcagatt tagtgacctt gtcagcgata
    45601 cggttacttg tgagccagta gtcgattctc cagcctgtat tgttgatttt agaagttttg
    45661 ctgcgttgtg cccaccaagt gtagcgttca ggaacatcgc catgaacatg gcggaaggtg
    45721 tctgtaaatc cagttgccaa aaggttggta aatccagcac gttcctcgtc agtaaatcca
    45781 ggtgaacggc ggttgctagc aggatttgca aggtcgattt cattgtgggc tacgttgtag
    45841 tcaccggtcg caaggactgg tttttctttg tctagttcag ccaaatactc agcatattta
    45901 acatcccaga cttggcgttc ttccaagcgt ttgagaccgt caccagcgtt tggagtgtaa
    45961 acttgggtta cgaaaaatgc atcaaattct agagtgatga tacggccttc caagtccatg
    46021 gtagaagggg caccgatttc tggaaaactg atcgtaggcg taagttcttt cttataaagg
    46081 aacatggttc cagcatagcc tttacgggca ggctcttggg aagagcgcca tgtgttttcg
    46141 tagcctggga agagttcttc taaaatttcc acgtgtttct ttgtaggtcc tttggcagaa
    46201 agcttggttt cttggatagc aatgatatca gcattttcag cgaccaaggt ttgtaggact
    46261 tcttgggaca atttggcacg agctgagtca ctagttaggg cagcgtttag ggaatcaata
    46321 ttccatgaga taagtttcat aaagttacct ttttcattca gattatagat tttattatac
    46381 caaaaaaaga tctatttccc caacgtatgg tttgaaaaat tactctcttt cgtttataat
    46441 taagaatgat tttatgaaag ggagtgaaaa tatatgaaat tctactctta tgactatgta
    46501 ctcagccaaa tcggtcagca aaatggtatc atggttggct ttgggattgt tctattagct
    46561 gtgacagttt tttttgcttt caaggcatac catgataaaa agggaaccga atttcgtgag
    46621 ttggtcatga tttcagctct ggccttattt agctctgctt ttggtcagca tcacgactta
    46681 tcaaaacaat caagtttcta acaataaatt tcaaacttca cttcatttca tcgaggttgt
    46741 ttccaaagat ttgggagtag acaagtcaga agtctatgtt aatacttcca caaacacaga
    46801 tggcgcactt atcaaggtgg gagatcgcta ttatcgtgcc ctaaacggaa gtgagccaga
    46861 caagtacctg ttagagaaag tcgaattgta taagacagac gcaattgaac tggtggatgt
    46921 gaacaaatga cacttaatta tatcgaaatt ttaatcaaac tggtcttgac tctcaaatgg
    46981 ctcaacaaca atgttcactt tgtgaaacgt ttgattgatg gtaagccaac tctccttatc
    47041 aaaaatggga atattgaccc agaagcctgt cgttcagttg gtttgtctgc atcggatgta
    47101 gccctcaaac ttcgtagcca agggattttc cagatgaagc aagtcaaacg agctgtgcaa
    47161 gagcaaaatg ggcaacttat cgttgtgcaa atgggagatg aaaatcctaa gtatccagtt
    47221 gtgactgacg gtgtgattca agtagatgtc ttggaatcga ttggtcgtag cgaagagtgg
    47281 ttgcttgata acctcagtaa acaagggcat gacaatgtag ccaatatctt tattgctgaa
    47341 tatgacaagg gtgctgttac agtcgtaact tatgaaaaag aaaaacctgg ggtcttgtac
    47401 tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtatgtagg ttactgactt
    47461 cgtcagttct atctacaacc tcaaagcagt gctttgagca gcctgcggct agtttcctag
    47521 tttgctcttt gattttcatt gagtattggc ctcaggtttc catttgcaat cagaaaggga
    47581 ttttatgtcc attattcaaa aactttggtg gtttttcaag ttagaaaaac gccgttatct
    47641 agtcggaatt gtggccctgg tcttggtttc cgtcctcaat ctcattcctc ctatggttat
    47701 ggggcgggtt attgatgcca tcacatcggg gcaattaacc cagcaggacc tccttcttag
    47761 cctattttac ttgctacttg cagcctttgg tatgtactat ttgcgctatg tgtggcgtat
    47821 gtatatcctt gggacctctt attgcttggg acagatcatg cggtctcgct tgtttaagca
    47881 tttcacaaaa atgtcgtcag ccttttatca aacctatcgg acgggtgatc tgatggcaca
    47941 cgcaaccaat gatatcaatg ccttgactcg tttagcaggt ggcggtgtca tgtctgcggt
    48001 ggatgcctct atcacggctc tggtgacttt gttgaccatg ctctttagca tctcatggca
    48061 gatgactctt gttgccattc tccccctacc tttcatggcc tatgcgacta gtcgcctagg
    48121 gagaaagact cataaggcct ttggcgaatc ccaagctgct ttttctgaac tcaataacaa
    48181 ggtacaggag tccgtatcag gtatcaaagt gaccaagtct ttcggttatc aggcagacga
    48241 gttgaagtct tttcaggcag tcaatgaatt aaccttccaa aagaacctgc aaaccatgaa
    48301 atatgatagt ctctttgacc ctatggttct cttgtttgtt ggttcgtcct atgttttaac
    48361 gcttttggtt ggctccttgg tggttcagga agggcagatt acagttggga atctagtcac
    48421 ctttatcagc tatttggata tgctggtctg gcctcttatg gccatcggct tcctctttaa
    48481 tactactcag cgagggaagg tttcttacca gcggattgaa aatcttttgt ctcaggaatc
    48541 tcctgtacaa gacccggagt ttcctctgga tggtattgaa aatgggcgtt tggagtatgc
    48601 cattgacagc tttgcttttg aaaatgagga aacactgacg gatattcact ttagtttggc
    48661 aaaagggcaa acactgggct tggttgggca gacaggctct gggaaaacgt ccttaatcaa
    48721 gctcctcttg cgtgaatacg atgtggataa gggcgccatt tatctaaacg gtcacgatat
    48781 tcgggactat cgtctgacag accttcgcag tctcatgggc tatgttcctc aggaccagtt
    48841 tctttttgcg acttcaatcc tagacaatat ccgctttggc aatcctaact tgcccctttc
    48901 agcggtcgag gaagctacta agctagcccg agtttaccaa gatattgtag acatgcctca
    48961 aggatttgat acgctgattg gtgaaaaagg agtcagtctt tctggtggtc aaaagcaacg
    49021 gttggctatg agtcgggcta tgattttaga ccctgatatc ttgattttgg atgattcctt
    49081 atccgccgta gatgccaaga cagagtatgc gattatcgac aacctcaagg agacgcgaaa
    49141 ggacaagaca accattatca ctgcccatcg cctgagtgca gttgtccatg cagatttgat
    49201 tttagtcctg caaaatggtc aaattatcga acgaggcagg cacgaagact tgctagcttt
    49261 ggatggctgg tatgcccaaa cctaccagtc tcagcagctg gaaatgaagg gagaagaaga
    49321 tgcagaataa acaagaacaa tggactgtat tgaagcgctt gatgtcctat ctcaagcctt
    49381 atggactcct tacctttttg gcactcagtt ttctcctagc gacgacggtc attaaaagtg
    49441 tcattcccct tgtggcttcc cactttatcg accagtatct cagcaatctt aaccaactag
    49501 ccgtgaccgt tttgctggtc tactatggtc tctacatcct acaaactgta gttcagtatg
    49561 tcggcaatct tctctttgcg cgcgtgtctt acagtattgt tagggatatt cgtcgggatg
    49621 cctttgccaa tatggagaaa ctgggcatgt cttactttga caagacgcca gcaggttcta
    49681 tcgtttctcg tttgaccaac gataccgaga cgattagtga tatgttttct gggattttat
    49741 ccagctttat ctcagcagtt tttatctttc tgacaaccct ttataccatg ttggtgctgg
    49801 attttcgttt gacggcttta gtcttgctct ttctcccctt gattttcctt ttggtcaatc
    49861 tctatcgaaa aaagtcagtg aaaatcatcg agaaaaccag aagtctcttg tcagatatca
    49921 atagtaagct ggcagagaat atcgagggaa tcaggattat tcaggctttt aatcaagaga
    49981 agcgcctgca ggcagaattt gatgaaatca accaagagca cttggcctat gccaaccgtt
    50041 ctgtagcctt ggatgccctc tttttgagac ctgccatgag tttgttgaaa cttctaggtt
    50101 atgctgtctt gatgacctat tttggctatc gtggtctttc tatcgggata acggccggga
    50161 ccatgtatgc ttttatccag tacatcaacc gcctctttga ccctttgatt gaggtgacgc
    50221 aaaacttttc aacactgcaa acgtctatgg tttctgcagg ccgtgtcttt gccttaatcg
    50281 atgagaggac ctatgagccc cttcaagaaa atgggcaagc caaagtcaaa gaaggcaata
    50341 tccgttttga acatgtgtgt ttctcgtatg acggtaaaca tccgattctg gatgacattt
    50401 ctttctctgt taataagggt gaaaccattg cctttgtagg tcatacaggt tcagggaaat
    50461 cgtctattat caatgtcctc atgcgctttt atgaattcca gtcagggaga gttctcttgg
    50521 atgatgtgga tatcagggat ttcagtcaag aagagctgag aaaaaacatc ggtttggttt
    50581 tacaggaacc cttcctctat catggaacta ttaagtccaa tatcgccatg taccaagaaa
    50641 tcagtgatga gcaggttcag gctgcggcag cctttgtgga tgcagattcc tttattcaag
    50701 aacttcctca ggggtacgac tcccctgttt ccgagcgtgg ttcgagcttc tctactgggc
    50761 agcgccagct tcttgccttt gctagaacag tcgccagcca gcctaaaatc ctgattttgg
    50821 atgaagcgac agccaatatt gactctgaaa cagaaagttt ggttcaagct tctctggcga
    50881 agatgagaca gggccgaaca actattgcta tcgctcaccg cctttctact attcaagacg
    50941 ccaactgcat ctatgtcttg gataagggac gcattatcga gagtggaacc catgaggaac
    51001 tcttgactct gggaggaacc tatcacaaga tgtatagttt gcaggcaggg gccatggcct
    51061 atactctttg aaaatctctt taaaccatgt cagctttatc tgcaatctca aagctgtact
    51121 ttgattttca ttgagtacta gaaggaaatc cttcaaatta cagatttctt tcaccgcctt
    51181 ttccattttg tggtataatg aaaaatgttg acaaatagta taataaaaac aaaggagaac
    51241 agcatgctga aatgggaaga cttgcctgtg gaaatgaaat caagcgaggt tgagtcttac
    51301 taccagcttg tctctaaaag gaagggttcg ctgattttca agcgttgctt ggactgggtt
    51361 ttggccttgg tcttactggt tctaacttct cccatctttc tcatcttgag catttggatc
    51421 aagttggata gcaaggggcc agtgatttac aagcaagagc gtgtgaccca gtacaaccgt
    51481 cggttcaaga tttggaagtt ccgtaccatg gtgacggatg cggataaaaa aggaagtctg
    51541 gtgacttctg ctaacgatag ccgtattacc aaggttggaa atttcatccg acgtgtccgt
    51601 ttggacgaac tgcctcagtt ggtcaatgtc cttaaaggtg agatgtcctt tgtcggtaca
    51661 cgacctgaag tgccacgtta tacagagcag tatagccctg aaatgatggc aaccttgctc
    51721 ttgcaagcag gaattacctc tccagccagc atcaactaca aggatgagga caccatcatc
    51781 agtcaaatga cggagaaagg tctgtcagtt gatcaggcct atgtggagca tgttcttcct
    51841 gaaaagatgc gctataacct cgcctatctc cgagagttta gtttctttgg ggacatcaaa
    51901 atcatgtttc aaaccgtgtt tgaggtacta aaataaagta gtcataagaa aatgagtaca
    51961 gataaaagga gcaaatcaat gccaaattac aatattccat tttcaccgcc tgatatcaca
    52021 gaagcagaaa ttgctgaagt agcggatacc ctgcgttctg gttggatcac aacaggtcct
    52081 aaaacaaaag aactggagcg ccgcttgtct ctttacacac agacacctaa gactgtttgt
    52141 ctcaactctg cgacagccgc tctggagttg attttacgcg ttttggaagt gggacctggt
    52201 gatgaagtca tcgttccagc catgacctat acggcttcat gtagtgtcat tacgcacgtg
    52261 ggagcaaccc ctgtcatggt ggatatccaa gcagatacgt ttgagatgga ctatgacctg
    52321 cttgagcaag ctatcactga gaaaactaag gtgattatcc cagtagagct cgcagggatt
    52381 gtttgcgatt atgaccgttt gttccaagtc gtggagaaaa aacgtgactt ctttaccgct
    52441 tcaagcaagt ggcaaaaggc ctttaaccgt attgtcattg tctctgatag tgcccacgct
    52501 ttgggatcta cttataaagg acaaccttct ggttctatcg ctgattttac ttccttctca
    52561 ttccatgctg ttaagaactt tacaacggca gaaggtggaa gtgcgacttg gaaagccaat
    52621 ccagtgattg atgacgaaga gatgtacaag gaattccaaa tcctttccct tcacgggcaa
    52681 actaaggatg ctcttgccaa gatgcaactg gggtcatggg aatacgatat cgttacacca
    52741 gcctataagt gcaacatgac cgatatcatg gcttcacttg gtttggtaca attggaccgc
    52801 tatccaagtt tgttgcaacg ccgtaaggac attgtggacc gctatgatag tggttttgca
    52861 ggttctcgca tccatccttt ggcacacaag actgaaactg tcgaatcttc acgccacctc
    52921 tacatcaccc gtgtagaagg agcaagccta gaagaacgca acctcatcat ccaagaattg
    52981 gctaaagcag gaattgcaag taatgttcac tacaaaccgc ttcctctctt gacagcctat
    53041 aagaatcttg gatttgatat gacgaactat cctaaggcct atgccttctt tgagaatgaa
    53101 attaccctcc ctcttcatac taaattaagc gatgaagaag tagactatat cattgagact
    53161 ttcaaaacag tttctgaaaa agtgctaact ttatcaaaaa aatgacaaac tacagtcaag
    53221 cgaaagtgat cctgtcccta aaaagtctaa ttgagtgtaa aaactgttgt tttcaattga
    53281 taatagttta cacctgtagt tgaggcctct ttctcctcag agagagaatt tttataggat
    53341 tttcctttct tgtgggagtc ccgtggtttg aaataagatg tgagcaattt ggtatagcat
    53401 ttagaatcct tactagacat catttagaaa atctagtgtc ttgttctagt tttcaattca
    53461 ccctattttt tgaaagacgt gagtttccat gagtgagatt gtggaaacta gcgtcttttt
    53521 tttgttttca gaatattgtt caaagttttg tgcctgtctt tcatgttcta gtcattcttt
    53581 tgcatgatag aatttatagc atgttgatat tataataacg caaatatccc atatgtttag
    53641 tgatgcttgc tatacatcat tagatctcct gcgagacaat ctataaaaca cttgtctacg
    53701 attacctata tgccctattc cagtatttta gaagcactgc atctattttt atcgaggtta
    53761 aatctagctt ttatagaagg tctatttaag aaatatattg tagtgtttta gtttcaatcc
    53821 gccatatgag cgatattcag gtaaatatcc ctggcgaatg cttgtatgac aaggtatttg
    53881 ttctttcatt tataatttac aacatatcaa caaatttaaa tatagtaaat gggatatttt
    53941 atattcaagc taagaaagat agcatcactt ttgaatggaa ggctaaagag caaactagga
    54001 agttggccat agatagctca aaaccctgct ttgaggttgt agatatagta aaatgaaaca
    54061 agaataggac aaattgatcg ggacagttaa atcgatttct aacaatgttt tagaagtaga
    54121 ggtgtactat tatagtttca gtctactata gaactgacca agtcagtaac ctagacttag
    54181 ggcaaggcgg cactgaccta gtttgaagag atttccgaag agtataaatt ttaatatttt
    54241 cttgtgttat tccttgacaa ttcaatttgg aaaatatatg ataaagataa tgacagcggt
    54301 gtcattctat ctattttaag aaaagtaata atcaattgtt aaaaatagta aaaaaattgg
    54361 aggttctgat gaaatatttt gttcctaatg aggtattcag tattcgtaaa ttaaaggtgg
    54421 ggacttgctc ggtactattg gcaatttcaa ttttgggaag ccaaggtatt ttatcggatg
    54481 aagttgttac tagttcttca ccgatggcta caaaagagtc ttctaatgca attactaatg
    54541 atttagataa ttcaccaact gttaatcaga atcgttctgc tgaaatgatt gcctctaatt
    54601 caaccactaa tggtttagat aattcgttaa gtgttaatag tatcagctct aatggtacta
    54661 ttcgttccaa ttcacaatta gacaacagaa cagttgaatc tacagtaaca tctactaatg
    54721 aaaataagag ttataaggaa gatgttataa gtgacagaat tatcaaaaaa gaatttgaag
    54781 atactgcttt aagtgtaaaa gattatggtg cggtaggtga tgggattcat gatgatcgac
    54841 aagcaattca agatgcaata gatgctgcag ctcaagggct aggtggagga aatgtatatt
    54901 ttcctgaagg aacttattta gtaaaagaaa ttgttttttt aaaaagtcat acacacttag
    54961 aattgaatga gaaagctaca attctaaatg gtataaatat taagaatcac ccttccattg
    55021 tttttatgac aggtttattt acggatgatg gtgcgcaagt agaatggggc ccaacagaag
    55081 atattagtta ttctggtggt acgattgata tgaacggtgc tttgaatgaa gaaggaacta
    55141 aagcaaaaaa tctaccactt ataaattctt caggtgcatt tgctattggg aattcaaata
    55201 acgtaactat aaaaaatgta acattcaagg atagttatca agggcatgct attcaaattg
    55261 caggttcgaa aaatgtatta gttgataatt ctcgttttct tgggcaagcc ttacccaaaa
    55321 cgatgaagga tgggcaaatc ataagtaagg agagcattca gattgaacca ttaactagaa
    55381 aaggttttcc ttatgccttg aatgatgatg ggaaaaaatc tgaaaatgtg actattcaaa
    55441 attcctattt tggcaaaagt gataaatctg gggaattagt aacagcaatt ggcacacact
    55501 atcaaacatt gtcgacacag aacccctcta atattaaaat tttaaataat cattttgata
    55561 acatgatgta tgcaggtgta cgttttacag gattcactga tgtattaatc aaaggaaatc
    55621 gctttgataa gaaagttaaa ggagagagtg tacattatcg agaaagcgga gcagctttag
    55681 taaatgctta tagctataaa aacactaaag acctattaga tttaaataaa caggtggtta
    55741 tcgccgaaaa tatatttaat attgccgatc ctaaaacaaa agcgatacga gttgcaaaag
    55801 atagtgcaga atatttagga aaagtatcag atattactgt aacaaaaaat gtaattaata
    55861 ataattctaa ggaaacagaa caaccaaata ttgaa
//
LOCUS       DAVLAQ010000007        53979 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000007 DAVLAQ010000000
VERSION     DAVLAQ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.007"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(424..516)
                     /locus_tag="VXB71_000398"
     CDS             complement(424..516)
                     /locus_tag="VXB71_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0450569.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            677..1648
                     /gene="ruvB"
                     /locus_tag="VXB71_000399"
     CDS             677..1648
                     /gene="ruvB"
                     /locus_tag="VXB71_000399"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0450570.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1629..2201
                     /locus_tag="VXB71_000400"
     CDS             1629..2201
                     /locus_tag="VXB71_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0450571.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2432..3190
                     /locus_tag="VXB71_000401"
     CDS             2432..3190
                     /locus_tag="VXB71_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0450572.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3199..4002
                     /locus_tag="VXB71_000402"
     CDS             3199..4002
                     /locus_tag="VXB71_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0450573.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4024..5283
                     /gene="rseP"
                     /locus_tag="VXB71_000403"
     CDS             4024..5283
                     /gene="rseP"
                     /locus_tag="VXB71_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0450574.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5296..7149
                     /locus_tag="VXB71_000404"
     CDS             5296..7149
                     /locus_tag="VXB71_000404"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0450575.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7249..8628
                     /gene="bglA"
                     /locus_tag="VXB71_000405"
     CDS             7249..8628
                     /gene="bglA"
                     /locus_tag="VXB71_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0450576.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            8820..10628
                     /gene="glmS"
                     /locus_tag="VXB71_000406"
     CDS             8820..10628
                     /gene="glmS"
                     /locus_tag="VXB71_000406"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0450577.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10747..11796
                     /locus_tag="VXB71_000407"
     CDS             10747..11796
                     /locus_tag="VXB71_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0450578.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(11896..15693)
                     /gene="spuA"
                     /locus_tag="VXB71_000408"
     CDS             complement(11896..15693)
                     /gene="spuA"
                     /locus_tag="VXB71_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0450579.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDTHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVKIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16109..16522
                     /gene="rpsL"
                     /locus_tag="VXB71_000409"
     CDS             16109..16522
                     /gene="rpsL"
                     /locus_tag="VXB71_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0450580.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16542..17012
                     /gene="rpsG"
                     /locus_tag="VXB71_000410"
     CDS             16542..17012
                     /gene="rpsG"
                     /locus_tag="VXB71_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0450581.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17436..19517
                     /gene="fusA"
                     /locus_tag="VXB71_000411"
     CDS             17436..19517
                     /gene="fusA"
                     /locus_tag="VXB71_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0450582.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19621..24012
                     /locus_tag="VXB71_000412"
     CDS             19621..24012
                     /locus_tag="VXB71_000412"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0450583.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24114..24377
                     /locus_tag="VXB71_000413"
     CDS             24114..24377
                     /locus_tag="VXB71_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0450584.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24370..24648
                     /locus_tag="VXB71_000414"
     CDS             24370..24648
                     /locus_tag="VXB71_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0450585.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24669..24821
                     /locus_tag="VXB71_000415"
     CDS             24669..24821
                     /locus_tag="VXB71_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450586.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            24843..26084
                     /locus_tag="VXB71_000416"
     CDS             24843..26084
                     /locus_tag="VXB71_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0450587.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26094..26324
                     /locus_tag="VXB71_000417"
     CDS             26094..26324
                     /locus_tag="VXB71_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0450588.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            26682..27404
                     /locus_tag="VXB71_000418"
     CDS             26682..27404
                     /locus_tag="VXB71_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0450589.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27621..28955
                     /gene="pepC"
                     /locus_tag="VXB71_000419"
     CDS             27621..28955
                     /gene="pepC"
                     /locus_tag="VXB71_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0450590.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(29011..29922)
                     /locus_tag="VXB71_000420"
     CDS             complement(29011..29922)
                     /locus_tag="VXB71_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0450591.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(29946..30749)
                     /locus_tag="VXB71_000421"
     CDS             complement(29946..30749)
                     /locus_tag="VXB71_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0450592.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30777..31766)
                     /gene="manX"
                     /locus_tag="VXB71_000422"
     CDS             complement(30777..31766)
                     /gene="manX"
                     /locus_tag="VXB71_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0450593.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(31999..33018)
                     /gene="adhP"
                     /locus_tag="VXB71_000423"
     CDS             complement(31999..33018)
                     /gene="adhP"
                     /locus_tag="VXB71_000423"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0450594.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(33370..34182)
                     /locus_tag="VXB71_000424"
     CDS             complement(33370..34182)
                     /locus_tag="VXB71_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0450595.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            34372..35790
                     /locus_tag="VXB71_000425"
     CDS             34372..35790
                     /locus_tag="VXB71_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0450596.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            35843..36550
                     /locus_tag="VXB71_000426"
     CDS             35843..36550
                     /locus_tag="VXB71_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0450597.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            36645..37619
                     /gene="folP"
                     /locus_tag="VXB71_000427"
     CDS             36645..37619
                     /gene="folP"
                     /locus_tag="VXB71_000427"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0450598.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            37621..38943
                     /locus_tag="VXB71_000428"
     CDS             37621..38943
                     /locus_tag="VXB71_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0450599.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            38924..39478
                     /gene="folE"
                     /locus_tag="VXB71_000429"
     CDS             38924..39478
                     /gene="folE"
                     /locus_tag="VXB71_000429"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0450600.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            39521..40333
                     /gene="folK"
                     /locus_tag="VXB71_000430"
     CDS             39521..40333
                     /gene="folK"
                     /locus_tag="VXB71_000430"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0450601.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(40378..40695)
                     /locus_tag="VXB71_000431"
     CDS             complement(40378..40695)
                     /locus_tag="VXB71_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0450602.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            41052..41498
                     /gene="rplM"
                     /locus_tag="VXB71_000432"
     CDS             41052..41498
                     /gene="rplM"
                     /locus_tag="VXB71_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0450603.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            41517..41909
                     /gene="rpsI"
                     /locus_tag="VXB71_000433"
     CDS             41517..41909
                     /gene="rpsI"
                     /locus_tag="VXB71_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0450604.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(42171..42593)
                     /locus_tag="VXB71_000434"
     CDS             complement(42171..42593)
                     /locus_tag="VXB71_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0450605.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            42740..42916
                     /locus_tag="VXB71_000435"
     CDS             42740..42916
                     /locus_tag="VXB71_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450606.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            43318..45531
                     /locus_tag="VXB71_000436"
     CDS             43318..45531
                     /locus_tag="VXB71_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0450607.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(45753..46229)
                     /locus_tag="VXB71_000437"
     CDS             complement(45753..46229)
                     /locus_tag="VXB71_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0450608.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQAQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            46452..49655
                     /locus_tag="VXB71_000438"
     CDS             46452..49655
                     /locus_tag="VXB71_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0450609.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYYWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            50035..50420
                     /gene="tnpA"
                     /locus_tag="VXB71_000439"
                     /pseudo
     CDS             50035..50420
                     /gene="tnpA"
                     /locus_tag="VXB71_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(50799..51428)
                     /locus_tag="VXB71_000440"
     CDS             complement(50799..51428)
                     /locus_tag="VXB71_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0450610.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(51438..52439)
                     /locus_tag="VXB71_000441"
     CDS             complement(51438..52439)
                     /locus_tag="VXB71_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0450611.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(52470..53111)
                     /locus_tag="VXB71_000442"
     CDS             complement(52470..53111)
                     /locus_tag="VXB71_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0450612.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(53130..53945)
                     /locus_tag="VXB71_000443"
     CDS             complement(53130..53945)
                     /locus_tag="VXB71_000443"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0450613.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT        15720 a        10163 c        12326 g        15770 t
ORIGIN      
        1 ttcggtattt ttcggatttt ggtcggggaa ttggcgggga cttttttagc gaatataact
       61 aagaaatagg tctgtggtcg cttcagctag ttcaaactca atttgattgt aagtgactgt
      121 taattgaaga actggaacta ctgtaataat gattttgctt gtctagtagt ggcgtattaa
      181 atgagaagta acatgtaaga ttgtctcttc gtttacgaaa tcaaaatttc tatgaaattg
      241 atagaatccc taacgttctc ttaatcttaa ccgtcttgtc gtacagcggt tgaagaaaat
      301 gtaaaccttt gacaaaattc gtgaactatg ggataataaa aaggaattga gtactagttc
      361 tatatcatag gctagaaaag accccaagct cacgaccaaa taagcttgag gtcttttttg
      421 acactatttg tccttgttta gccatttatc gactatacga agaacgacac cgaccacaat
      481 tggtccgatg atagttttga gtactaattc catcatgggc tatctcacct cctttcgtag
      541 gcggtgtagc agtgtcgtag aatattatac cacataagtg ctaaacttag gagtcaccca
      601 atcaggtggc ttttttgttt gtggcttggt tttttgatat aatagagcca tgagtagaat
      661 tttagataat gagataatgg gggatgagga gttagtagaa cgcacgctcc gtcctcagta
      721 tttacgtgaa tatatcggac aggataaggt caaggaccag ctacaaatct ttattgaagc
      781 tgccaaaatg cgggatgaag cgctggatca tgtgctctta tttgggcctc caggtctcgg
      841 gaaaacgacc atggcctttg ttattgccaa cgaactggga gtcaatctta agcagacgtc
      901 gggtccagtc attgaaaaag ccggagatct ggtagctatt ttgaatgagt tagagcctgg
      961 ggatgtactt tttattgatg agatccatcg tttgccaatg tcagtggaag aggtgcttta
     1021 tagtgctatg gaggacttct acatcgatat tatgattggg gctggtgagg gtagtcgtag
     1081 tgttcatttg gagttaccac cttttacctt gattggtgcg acgactcggg ctggtatgct
     1141 ctccaatccg ctacgggcac gttttgggat tacaggccat atggagtatt atgcccatgc
     1201 tggcttgaca gaaattgtcg agcggacggc agatattttt gagatggaaa tcactcatga
     1261 ggcagcatct gagttggccc tacgtagtcg tgggacccct cgtattgcca atcgtctcct
     1321 caagcgcgtg cgcgattttg cccagataat ggggaatggg gtaattgatg atattattac
     1381 cgataaggct ttgactatgc tggatgttga ccatgaaggt ttggactatg tggatcaaaa
     1441 aatccttcgt accatgattg agatgtacag tggaggacct gttggtctag gaactctttc
     1501 tgtgaatatc gccgaagagc gtgagacagt tgaagatatg tatgagcctt acttgattca
     1561 aaaaggtttt atcatgcgga cacggtctgg acgggtggcg actgctaagg catatgagca
     1621 cttaggttat gaatacagtg aaaaataagc aagaaatctt agaggctttt agagaaaatc
     1681 cagatatgat ggccattctg acgatcatcc gagaccttgg tctgaaagac tcgtggttgg
     1741 cagcaggttc tgtcagaaat ttcatttgga atcttttgtc agacaaatcc ccttttgatc
     1801 atgaaacaga tatagatgtg attttctttg atccagattt ttcttatgag gaaaccttat
     1861 tactggagaa aaagctgcga gaggattttc ctcagtacca gtgggaattg aaaaatcagg
     1921 tctatatgca tcagcacagt cctcacactg cttcctatac cagttctcgt gatgctatga
     1981 gtaagtatcc agaacggtgt acgacagttg gactgcgctt gaatgaagaa tcagattttg
     2041 aactctatgc accttatggt ttggaggata ttttgaattt tcaagttcgt ccaactcctc
     2101 atttcttaga aaatgaagac cgaatggaac tctatcaaac acgtttatcc aagaaaaatt
     2161 ggcaggagaa atggaaaaat ttgattttta aaaatactta aggaaacttt aagctaggga
     2221 gtgtacacta agttcataag ttaagaagac cttaacttaa actcctaaaa ctttttcata
     2281 ataatctccc tataaaaata aagtcgccta atcaggcggc ttattttttt gaaaaatggg
     2341 cttggtgcct gagaataaat agcttagtga tagaagaaaa tggggaaata tggtataatg
     2401 aaacgataga tttttgaata ggaataagat catgtttgga ttttttaaga aagataaggc
     2461 tgtggaagta gaggttccga cacaggttcc tgctcatatc ggcatcatca tggatggcaa
     2521 tggccgttgg gctaaaaaac gtatgcaacc gcgagttttt ggacacaagg cgggcatgga
     2581 agcattgcaa accgtgacca aggcagccaa caaactgggc gtcaaggtta ttacggtcta
     2641 tgctttttct acggaaaact ggacccgtcc agatcaggaa gtcaagttta tcatgaactt
     2701 gccagtagag ttttatgata attatgtccc ggaactacat gcgaataatg ttaagattca
     2761 aatgattggg gagacagacc gcctgcctaa gcaaaccttt gaagctttaa ccaaggctga
     2821 ggaattgact aagaacaaca caggattgat tcttaatttt gctcttaact atggtggacg
     2881 tgctgagatt acacaggcgc ttaagttgat ttcccaggat gttttagatg ccaaaatcaa
     2941 cccaggtgac atcacagagg aattgattgg taactatctc tttactcagc atttgcctaa
     3001 ggacttacga gacccagact tgattatccg tactagtgga gaattacgtt tgagcaattt
     3061 ccttccatgg cagggagcct atagtgagct ttattttacg gacaccttat ggcctgattt
     3121 tgacgaagca gccttgcagg aagctattct tgcctataat cgtcgccatc gccgatttgg
     3181 aggagtttag gaggaaatat gacccaggat ttacagaaaa gaaccttgtt tgcagggatt
     3241 gccctggcta ttttcctacc aattttaatg attgggggcc tcttgcttca gatagcaatc
     3301 ggaatcatag ccatgctagc catgcatgaa cttttgaaga taagaggtct agcgaccatg
     3361 acgatggagg gcctcttgac tctctttgca acctttgcat taaccattcc cttggagaat
     3421 tacctgactt ttttgccagt tgatgggaat gtggttgcct atagtgtttt gatttcaatc
     3481 atgttaggaa cgaccgtttt tagcaagtct tatacgattg aggatgcggt tttccctctt
     3541 gctatgagct tctacgtggg ctttggattt aatgctttac tagatgctcg tgttgcaggt
     3601 ttggacaagg ctctcttagc cttgtgtatc gtctgggcga cagacagtgg tgcctatctt
     3661 gttgggatga actatgggaa acgaaagtta gcaccaaggg tatcgcctaa taaaaccctt
     3721 gagggtgcct tgggtggtat tttaggagca attttagtaa ccattatctt tatgatagtt
     3781 gacagtacag ttgctcttcc atatggaatt tacaagatgt cagtctttgc tattttcttt
     3841 agcattgctg gacaatttgg tgatttacta gaaagttcga tcaaacgtca ttttggtgtt
     3901 aaggattctg ggaaatttat ccctggacat ggtggtgttt tggatcgttt cgatagtatg
     3961 ttgcttgtat ttccaatcat gcacttattt ggactctttt aatcaaaaga cggaggaaac
     4021 gctatgctcg gaattttaac ctttattctg gttttcggga ttattgtagt ggtgcacgag
     4081 ttcgggcact tctactttgc caagaaatca gggattttag tacgtgaatt tgccatcggt
     4141 atgggaccta aaatttttgc tcacattggc aaggatggaa cggcctatac cattcgaatc
     4201 ttgcctctgg gtggctatgt ccgcatggcc ggttggggtg atgatacaac tgaaatcaag
     4261 acaggaacgc ctgttagttt gacacttgct gatgatggta aggttaaacg catcaatctc
     4321 tcaggtaaaa aattggatca aacagccctc cctatgcagg tgacccagtt tgattttgaa
     4381 gacaagctct ttatcaaagg attggttctg gaagaagaaa aaacatttgc agtggatcac
     4441 gatgcaacgg ttgtggaagc agatggtact gaggttcgga ttgcaccttt agatgttcaa
     4501 tatcaaaatg cgactatctg gggcaaactg attaccaatt ttgcaggtcc tatgaacaat
     4561 tttatcttag gtgtcgttgt tttttgggtt ttaatcttta tgcagggtgg tgtcagagat
     4621 gttgatacca atcagttcca tatcatgccc caaggtgcct tggccaaggt aggagtacca
     4681 gaaacggcac aaattaccaa gattggctca catgaggtta gcaactggga aagcttgatc
     4741 caagctgtgg aaacagaaac caaagataag acggcaccga ctttggatgt gactatttct
     4801 gaaaagggga gtgacaaaca agtcactgtt acacccgaag atagtcaagg tcgttacctt
     4861 ctaggtgttc aaccgggggt taagtcagat tttctatcca tgtttgtagg tggttttaca
     4921 actgctgctg actcagctct ccgaattctc tcagctctga aaaatctgat tttccaaccg
     4981 gatttgaaca agttgggtgg acctgttgct atctttaagg caagtagtga tgctgctaaa
     5041 aatggaattg agaatatctt gtacttcttg gcaatgattt ccatcaatat tgggattttt
     5101 aatcttattc cgattccagc cttggatggt ggtaagattg tgctcaatat cctagaagcc
     5161 atccgccaca aaccattgaa acaagaaatt gaaacctatg tcaccttggc cggagtggtc
     5221 atcatggttg tcttgatgat tgctgtgact tggaatgaca ttatgcgact cttttttaga
     5281 taatcgagga atattatgaa acaaagtaaa atgcctatcc caacgcttcg cgaaatgcca
     5341 agcgatgctc aagttatcag ccatgctctt atgttgcgtg ctggttatgt tcgccaagtt
     5401 tcagcaggtg tttattctta tctaccactt gccaaccgtg tgattgaaaa agctaaaaac
     5461 atcatgcgcc aagaattcga aaagattggt gctgttgaga tgttggctcc aacccttctt
     5521 agtgcagaat tgtggcgtga atcaggtcgt tacgaaacct atggtgaaga cctttacaaa
     5581 ctaaaaaacc gtgaaaaatc agactttatc ttaggtccaa ctcacgaaga aacctttaca
     5641 gctattgtcc gtgattctgt taaatcttac aagcaattgc cactcaacct ttatcaaatt
     5701 cagcccaagt atcgtgatga aaaacgccca cgtaatggac ttcttcgtac acgtgagttt
     5761 atcatgaagg atgcttatag tttccacgct aactatgata gtttggatag tgtttatgat
     5821 gagtacaaag cagcctatga gcgtattttc actcgtagtg gtttagactt caaggctatt
     5881 attggtgacg gtggagccat gggtggtaag gatagccaag aatttatggc cattacatct
     5941 gctcgtacag accttgaccg ctgggttgtc ttggacaagt cagttgcctc atttgacgaa
     6001 attcctgcag aagtgcaaga agaaatcaag gcagaattgc tcaaatggat agtctctggt
     6061 gaagatacca ttgcttactc aagtgagtct agctatgcag ctaacttaga aatggcaaca
     6121 aacgagtaca aaccaagcaa ccgtgttgtc gctgaagaag aagttactcg tgttgcaacg
     6181 ccagatgtta aatcaattga tgaagttgca gccttcctca atgttccaga agaacaaacg
     6241 attaaaaccc tcttctacat tgcagatggt gagcttgttg cagcccttct agttggaaat
     6301 gaccaactca acgaagtcaa gttgaaaaat cacttgggag cagatttctt tgacgttgct
     6361 agcgaagaag aagtggcgaa tgttgttcaa gcaggatttg gttcacttgg accagttggt
     6421 ttgccagaga atattaaaat tattgcagat cgtaaggtgc aagatgttcg caatgcagtt
     6481 gtcggtgcta acgaagatgg ctaccacttg actggtgtga acccaggccg tgattttact
     6541 gcagaatatg tggatatccg tgaagttcgt gagggtgaaa tttccccaga tggacaaggt
     6601 gtccttaact ttgcgcgtgg tattgagatc ggtcatattt tcaaactcgg aactcgctac
     6661 tcagcaagca tgggagcaga tgtcttggat gaaaatggtc gtgctgtgcc aatcatcatg
     6721 ggatgttacg gtatcggtgt cagccgtctt ctttcagcag tgatggagca acacgctcgc
     6781 ctctttgtta acaaaacgcc aaaaggtgaa taccgttacg cttggggaat caatttccct
     6841 aaagaattgg caccatttga tgtgcatttg attactgtca atgtcaagga tgaagaagcg
     6901 caagccttga cagaaaaact tgaagcaagc ttgatgggag ctggttatga agtcttgaca
     6961 gatgaccgta acgaacgtgt cggtgttaaa tttagcgata gtgacttgat tggtcttcca
     7021 atccgtatca ctgttggtaa aaaagcggcc gatggcattg tagaagttaa gatcaaggca
     7081 actggtgaca ccattgaggt tcatgcagat aacgtgcttg aaacgcttga aatcctaagc
     7141 aagaaataaa aactataatc agaagaaaaa caaggaaaaa atgtaactag tttttacctt
     7201 gttttttctg tataatggga gaaatgagta gataaagagg taaatgttat gctaagattt
     7261 ccaaaggatt ttgtctgggg atcctctact tctggaccgc agacagaagg acgtgtagct
     7321 ggtgacggta agggagacaa tctctgggat tactggttcc aagtggagcc aaatcgttac
     7381 tataatggga ttggttcaga taagacatcg actttttatg aaaattggga gcgggatatt
     7441 gagcttttgt tagagactgg tcacacagtc tttcggactt ctattcagtg gtcacggatt
     7501 tttccacaag gctgtggaaa agtcaaccct caaggtgtgg atttttatcg taaggtcttt
     7561 gaggctatta aggctaaagg aattcgtctg ttagtcaatc tctatcattt tgatttacct
     7621 tttgctcttc aagaggatgg tgatggttgg gaaaataagg cgacagtctc agcctatgaa
     7681 gactatgctc gtttttgttt tgagacttat ggagatttag tggatcaatg gattaccttt
     7741 aacgagccca tcgttcctgt agaatttggt tatttttatg atgcccatta tccacataag
     7801 gtggatgcag aggcagctgt taaggtagcc tatcatacac aattggccag cagccgggct
     7861 gttaaggctt gccatgaact tttgcctgat tccaagattg ggattgtcct caacttgaca
     7921 ccggcttatc cacgtagcca gcatcctgct gatgtcaagg cagctcgtat tgcggccctt
     7981 tttcaggccc aatctttctt agatccatct gtcttgggga cttatccaca ggagttggta
     8041 gaaatcttgc atgaacacgg tcttttacct gatgctacag aggaagagtt ggaactcatt
     8101 cgtgataata cggtggactt ccttggtgtg aactactatc aacctttgcg tgttatggct
     8161 cctcgatttg ctaagcatcc agatagtcca ctcttaccag aacattttta cgagccttat
     8221 gtgatgcctg gacgtaaaat caattctcac cgtggttggg agatttatga gcaagggatt
     8281 tatgacatcg cccaaaatat caaggaaaat tatggcaata ttgagtggat gttgactgag
     8341 aatggtatgg gtgttgaagg ggaagaaaaa ttccgtcaag atggaatgat tcaagatgat
     8401 taccgtattg actttgtaaa aggtcatctt cgtgaacttc accgtgccat tgaagatggt
     8461 gccaactgta agggctactt gatttggacc tttattgact gctggtcatg gctcaacagc
     8521 tataaaaatc gctatggttt ggtcgaatta gacttggaaa cgcaagaacg tcgtctgaag
     8581 aaatcaggcc actggttcaa agaattaagc gataataatg gattttaaaa aggactctga
     8641 ctgattatcc caatcggtca gagttttttg cttacaggag cttaatttga actataccaa
     8701 tttttactct tgacaagtga aagaaacaag tatatactgt ttttgctgat tctataaaag
     8761 atgaattaga ctataccaat tttaaggaga aagcacagct tgcctgtgtc gtatatacta
     8821 tgtgtggaat tgttggtgtt gttggaaaca caaatgcaac tgatattttg attcaagggc
     8881 ttgaaaagct tgaataccgt ggctatgatt ctgcgggaat ttttgtccta gatggtgctg
     8941 ataaccattt ggtgaaggct gttggtcgta tcgcagaatt gtctgccaag acagctggtg
     9001 ttgagggaac aactggtatc ggacatactc gttgggcaac tcatgggaaa ccaacggaag
     9061 acaatgctca cccacaccgc tctgagacag aacgttttgt cttggttcac aatggggtga
     9121 ttgaaaacta ccttgaaatt aaagaagaat accttgctgg gcaccacttc aaagggcaaa
     9181 cagatacgga aatcgccgta catttgattg gaaaatttgc ggaagaagac ggtctctcag
     9241 ttcttgaagc ctttaaaaaa gctcttcata ttatccgtgg ttcatatgcc tttgccttga
     9301 ttgactctga aaatccagat gtcatctatg tagcgaaaaa caaatctcca cttttgattg
     9361 gtcttgggga aggctacaat atggtctgct cagatgctat ggctatgatt cgtgaaacca
     9421 accaatacat ggaaattcat gaccaagagt tggtaatcgt caaggctgat agcgtggaag
     9481 ttcaagacta tgatggtaac agtcgtgaac gtgctagcta tactgcggaa cttgacttgt
     9541 cagatatcgg taagggaact tatccttact acatgcttaa ggaaattgat gagcaaccaa
     9601 ctgttatgcg taaactcatt caagcctaca cggatgatgc tggtcaagta gtgattgatc
     9661 ctgctatcat taaggctgtt caagacgcag accgcatcta catccttgca gctggaacat
     9721 cttaccatgc aggatttgct tctaagaaaa tgttggaaga attgacagat acaccagttg
     9781 aacttggcat ctcatctgag tggggctacg gtatgccact tctcagcaag aaaccactct
     9841 tcatctttat cagccaatct ggtgaaacag cggatagtcg tcaagttttg gtcaaggcta
     9901 atgaaatggg aattccaagc ttaacagtga caaacgttcc aggttcaacc ctctcacgtg
     9961 aagccaacta taccatgctc cttcacgcag gtcctgaaat tgccgtggca tcaactaaag
    10021 cctatacagc gcaaatcgca gcccttgcct tccttgcaaa agcagtcgga gaagcaaatg
    10081 gtaatgctaa agcgcaagcc tttgacctgg ttcatgaatt gtcaatcgta gctcagtcta
    10141 tcgaatcaac tctttcagag aaagaaacca ttgaagccaa ggttcgtgaa cttcttgaaa
    10201 caactcgtaa cgccttttac atcggacgtg gtcaagatta ctacgtagcc atggaagcaa
    10261 gtctcaaact caaagagatt tcttatatcc agtgtgaagg ttttgcggca ggagaactca
    10321 agcacggaac cattgccttg attgaagaag gaacacctgt cttggctctc ttgtcagatc
    10381 cagtccttgc caaccacact cgtggaaata tccaagaggt ggcagcccgt ggtgctaagg
    10441 tcctcactat cgcagaagaa aatgttgcta aagataccga cgatatcgtc cttacgactg
    10501 tacaccctta cctctcacca atttcaatgg tcgtaccgac gcaattggtt gcttactttg
    10561 caaccctcca ccgtggcctc gatgtggata aaccacgtaa ccttgctaaa tcagtaacgg
    10621 tagaataagc taaaaaagtc tagttatcta ggctttttct aatgagcaaa ttggttgctt
    10681 gtactcaaga ttcgtgttag aataattttt caaattgaag gacagagata gacaaggaga
    10741 atcacaatgg tagaattggg aatttcaaca tttggggaaa taacggagct tgaagggact
    10801 ggacaaactt acagtcatgc tgaacgcatt cgccagttgg tggcagagat tgagctggct
    10861 gacaaggttg gtttggacgt atatgggatt ggcgagcacc atcgggcgga ttttgcagta
    10921 tcagccccag agattgtcct ggccgctggg gcagtcaata ccaagaaaat ccgtttgacc
    10981 agtgcagtca gcattctgtc aagcatggat ccgattcgtt tgttccaaca gtatgccact
    11041 atcgatgctt tgtcaaatgg acgatcggag attatggctg gaaggggctc tttcacggaa
    11101 tctttccctc tgtttggtta tgacttgaaa gactacgact ctctttttga tgagaaatta
    11161 gacttgcttc agttagtcaa tgaaaagacc aagttagact ggcaaggtcg attgactcaa
    11221 acgattgctg gtaaagaagt ttatcctcgc ccagttcagg acaaattgcc cttgtggata
    11281 gctacaggtg gtcatgtcga atcaacagtg aagattgctc aggctggtct accgattgta
    11341 tatgctatta ttggtggtaa tccacgttat tttaaaaagt tgattcaggc ttatcgtgag
    11401 attggaagcg aagcgggcca tgctgacaaa gacttgaaag tgggagccca ttcttggggg
    11461 tggattgcgg aagatggtga gcaggcggtg aaagattatt tccatccgac taagcaagtg
    11521 gtggatgcta tttccaaaga ccgtccgcac tggcaggaat tgcgttatga gcaatatttg
    11581 gagcaggtag ggccaaatgg cgccatgttt gttggcaatc cagatcaggt ggccgaaaaa
    11641 ttgattcgca tgatagagga tttaggattg gaccgcttca tgcttcatct accgcttggt
    11701 tctatgcctc atgaccaggt tctgagagct attgaactct tcggaacaca agttgcaccc
    11761 aaagtacgag cttattttgc tatgaaagag gcttaataaa aaatcctaat caagtttatt
    11821 aggacaacaa atattgtaca aaaattaatc ccccgagcta taatgcttgg gggatttttc
    11881 tataggaggg ctagtttagt tctctttttt attttttagt aagaaaccga gaccaaggag
    11941 cgcaaggagg ctgattcctg caaataggag tttgttttcg tttttgattc ctgtatttgg
    12001 aagttcagct tgtttatctg gggttgcagg tatattttcc ttgctagagt tttctaccga
    12061 ttcgtttcga accgcttctt ttacagatgc ttcttgtgct tcttgtgctg gttgttcagc
    12121 ttgtgaatca gctgtagctt ggctaggttt attttccgca tcagctactt tggcatctgg
    12181 tttagtagaa tcaggtctag cttctggagc tgggtcttga tgtgcagggt gagaagcttc
    12241 attttgatgt tcaggcttgg aaggggttga gtctggtttc tcttctgcag ttgactcatg
    12301 gctagttcca ttttgagaga ctcgaagaac agtagctgta agggcattca atttcaagcc
    12361 tttttcagtc cattcaagtc ctttcgggtt ggcaattttg actgatcctg cttggttttc
    12421 atctgccaaa acttccgcat ttcttagatg tgcaaaggca gttcccaaat taaattcgcg
    12481 agctttttca tccgcattga caaagactgc gtagatatcg ccgtttggag cagtgatttg
    12541 gtagccaatc actacatcct ctttttccac accattttgg cctgggacag tgatgaggtg
    12601 gacacggtct ttgatatctt ggagactctt aagtcggaag gcatctgtag attgacgaag
    12661 ggcaatcaaa cctttcatat agtcacggct cttgacattt tcaggataag ctttaccatc
    12721 tgtagcctta gtccagtcaa acttgttgac tgcgtcgcta gaatcgtaag aatcatggat
    12781 gaagtaagga tagtcaaatg ggttgccgtc cttatcacgc aacaagtgag atttgtttgg
    12841 aaccttatcc tctgctactg gagtcttgta ggctgggtca cggaattgtt tagtacgtcc
    12901 atattcctga ccggagtgga taaatggagt tccttgagct gtcaagacca tgagatttcc
    12961 aagtcgtaaa cgacggtgga tttcagcata gttctcagcc ttgcttgggt cttttttgat
    13021 agactgggca atgatgtcaa agagggtcaa gttatcatgg gctgctatgt attggatgac
    13081 atctccaggg ctgtcagctt caaagttagt tggttgagca atgagatttt taaagatggt
    13141 gttgacatca cgcttgccac ctgtgataaa ggcaggttga ccttcgtttg gataaccaga
    13201 tttgaggttg ttacggatgt catctgaaaa gacagcgaca gtatcggtat gtttcatcca
    13261 atcttggtca gcagctttag taggcatgtt ttcatcaccg gcataggttc tccaaccttc
    13321 accaagcatg atgaggtttg gattgagggc gcgtgcagcc ttgtaagctt cttcgataga
    13381 agcggcgtca tggtctccca tcatatcgaa acggaatcca tccactttgt aggtatcaac
    13441 taggtatttg atagagtcaa ctaggagccg tttggtcata tggtgggttg ttcccaagcg
    13501 tccaccacca aagctagttc gaggtgtgcc atcggcatcc ataaagtggt agtagtttgg
    13561 ctctaggtct tcaaagatat cgactttggc tgtgtggtta taaacgacat ctaggatagc
    13621 tcccatacca cgtttgtgga tttcgttgat gaggttttta aattctgcga ttcgtttttc
    13681 tggattctta ggatcgcttg agtacatacc agtcaaggag aagtagtttt gagggtcata
    13741 tccccagttg tagttgctgt tgcttgaagc gtagtcagac aagcgttcat ggtttttcaa
    13801 ttcattgaca aagtagtaag acaagactgg aaggagctgg atatgggtta cacccaagtc
    13861 tttgagatag tctagttttt caatgaaggc ttcaaaagtc ccaaatggtt tggtcaagtc
    13921 ttttgcaatg gcaggatctg aagtgaagtc acgcacatga gcttcgtaga taacggcgtc
    13981 ttcacgagtc ttgaaattgt gaatcttacc ataagtcaag tcttgaggtc cgagtttagc
    14041 tggatctaca aaggcggctt tagccacttt atgggtatcg tcaattttgg catcgtcgct
    14101 attccaagca gcaagagatt tagcgtaagg atcgagtgca agaacagttt taccttgacg
    14161 ctcgatttgg tattgataat agtagccagt gaaatctgtg attccgagtt tgtttgtgct
    14221 gtctagagtt tgtttccaag ttcctctttc ccctttttcg agagcgacag ttccaactac
    14281 tttgtcaggg tcattcttgt cgtagacaac aacagaaacc ttatcagcac ttggtgacca
    14341 aagggtcaaa tcaacttgtt ttccttcttc ttttaggtca gctcccagtt tgccatcata
    14401 gctgtatgtc tcatctttca ggtgccagct tgttttggta gtgaattggt cggaattgta
    14461 gctaacagta taagggtgtt ttgtgtcaga gaaatctccg ctgtaggtca ctttcttacc
    14521 agcttcatcg attgcaacat cggtaatagt taccttgttt cctaggtgat tagtgatgtt
    14581 ggagtgtttg aggatatctt cttttttagc accgacaagt gttgaaaagc tactttcaat
    14641 gctagaagtg cctacgtgtt gggctcctgt catacggata tcatggacat agtatggatt
    14701 tgtgtaaatc gattcatcat cgtcttttag gaaaatttgg ctatgatttt tcaaatctgt
    14761 gaacttataa ttttctttac ggattttcac gtcgtctcct tgtttgctct catctagtaa
    14821 taaaaatcca aattctcttg cggcttcatt aagaggaatg tcgatatagc ggccatattt
    14881 gcctgtagcc gtaaagtctg ttccgtcagg ccattgagcg ctacttggat ttttcacatc
    14941 tccccagtac cagagagatt tcttgtcata gttgccatct gtgcggtagt agttgacgcg
    15001 aacagttcct gcaggctgtg gctcgtaaga gaaaaccttg taatcttggt ctaaccaagc
    15061 ttcgttcatt tttggaacta gtttttctac agatttatcg ccggttagat tttttccagc
    15121 tgtattgttg atgaggaagc taattttctt ggcttgttct ccctttaatt tgacatctag
    15181 gtaatagccg tagtcatctt tcttggcatc cttgaaggac aaagctccgt ttggccagtt
    15241 ttcagatggt ttttcaacat cgtcccaagt ccatagtcct tgagcatcct tgttttcttc
    15301 aggaagtttt ttgacatgga tacggaagta gttatcttcg atgggctctt ctgccttagt
    15361 ttcagttgtt actggactag tagaagtagt tggctctgtt gcaggttttt cttctgtttt
    15421 ctctagggaa gcgtttgcat ttctaggtga agaaatatca ctttcgttct taccagagcc
    15481 agctgctgta tcagtaagag gttgggcaag ggtggttgta tttctgttgt tgggttcgtt
    15541 agtggttggt gtactttcgt cggatgagat agttggtgta gccatggcaa gcaagacaag
    15601 gcttgcgccg ataaggacag aaccagttcc atttttgagg gaacggatgc tgtagaccat
    15661 ttttttctca gtgtgagatg gtgtttttct cataatgatt ctccaatcaa taaatttcta
    15721 tatcagtata gcatgtagta aaacaatatg caagcgtttt ctttgatttg tgaaaaaatt
    15781 cttacttttg agaagttttc tgtactattt tatatatcag tataaatgac ggagataaaa
    15841 atgtcacata agccaagccg tattattagg aagatgatgt gttcccagct atttttattc
    15901 agaaattgat ctctaacatt accaataaaa aagaaaaata tcttgacaag caagggaaaa
    15961 ttttgttaca ataatagacg gtacttttta cttttggtct ctcaagagtg tacagggacg
    16021 tgctgacaaa tgttgcaaaa gtacacacag atgatatctg tcaccaagtg tatcatcacc
    16081 aaaaataaaa aaacacagga gaatgtagat gcctacaatt aaccaattgg ttcgcaaacc
    16141 gcgtaaatca aaagtagaaa aatctaaatc accagctttg aacgttggtt acaatagtca
    16201 taaaaaagtt caaacaaacg tttcttcacc acaaaaacgt ggtgttgcaa ctcgtgttgg
    16261 aacaatgaca cctaaaaaac ctaactcagc ccttcgtaaa ttcgctcgtg tacgtttgag
    16321 caaccttatc gaagttactg cctacatccc aggtatcgga cacaacttgc aagagcacag
    16381 cgtggtgctt cttcgcggtg gacgtgtaaa agaccttcca ggggtacgtt accatatcgt
    16441 ccgtggtgca cttgatactg caggtgttaa cgatcgtaaa caaggccgtt ctaaatacgg
    16501 tactaaacgt ccaaaagcat aaggaaaggg gataaagaga aatgagtcgt aaaaatagag
    16561 ctccaaaacg tgacgtattg ccagatccgc tatacaattc acaactagtt actcgtctta
    16621 tcaaccgcgt tatgcttgat ggtaaacgtg gtactgctgc ttcaatcgtt tacggtgctt
    16681 ttgagcaaat caaagaagct actggcaacg atgcacttga agtatttgaa acagctatgg
    16741 aaaacatcat gcctgtactt gaagtacgtg cacgtcgtgt tggtggttct aactaccaag
    16801 tcccagttga agttcgtcca gaacgtcgta caacacttgg acttcgttgg ttggtaacaa
    16861 tcgctcgtct tcgtggtgaa cacacaatgc aagaccgtct tgcaaaagaa atcttggatg
    16921 ctgctaacaa cactggtgca gcagttaaga aacgtgaaga tactcaccgt atggctgaag
    16981 ctaaccgtgc attcgcacac ttccgttggt aagataggat gcgaaagcgt taagaaagtc
    17041 ccagagaaaa tagggaatcg aagcaggttg cggttgcaac caatgagatt catctttttc
    17101 tccagacttt tagcttgagc tcaactaaat catgatgcta ggcacggaag gatgcaaggt
    17161 gaaaatagga aactgacgca gtattcaacg aatacaagga gttttatctt tttcacgcag
    17221 catcccgttc cagctcacat cggctaacta actttagcct gggttcaaat tagctaaatc
    17281 gattagtatt agctataact cagcttacca tctcgtaagt tgaaaccaac aatagcatga
    17341 aaacattgag aacgggtagg tcctgcctat ccgtttttat taaaatcgtg ttataataga
    17401 atagaaatca aaaataaata ggagaaacaa acctcatggc acgcgaattt tcacttgaaa
    17461 aaactcgtaa tatcggtatc atggctcacg tcgatgccgg taaaacaaca actactgagc
    17521 gtattcttta ctacactggt aaaatccaca aaatcggtga aactcacgaa ggtgcgtcac
    17581 aaatggactg gatggagcaa gagcaagaac gtggtatcac gatcacatct gctgcgacaa
    17641 cagctcaatg gaacaaccac cgcgtaaaca tcatcgacac accaggacac gtggacttca
    17701 caatcgaagt acaacgttct cttcgtgtat tggatggtgc ggttaccgtt cttgactcac
    17761 aatcaggtgt tgaacctcaa actgaaacag tttggcgtca agcaactgag tacggagttc
    17821 cacgtatcgt atttgccaac aaaatggaca aaatcggtgc tgacttcctt tactctgtaa
    17881 gcacacttca cgatcgtctt caagcaaatg cacacccaat ccaattgcca atcggttctg
    17941 aagatgactt ccgtggtatc attgacttga tcaagatgaa agctgaaatc tatactaacg
    18001 accttggtac ggatatcctt gaagaagaca tcccagctga ataccttgac caagctcaag
    18061 aataccgtga aaaattgatt gaagcagttg ctgaaactga cgaagaattg atgatgaaat
    18121 acctcgaagg tgaagaaatc actaacgaag aattgaaagc tggtatccgt aaagcgacta
    18181 tcaacgttga attcttccca gtattgtgtg gttcagcctt caaaaacaaa ggtgttcaat
    18241 tgatgcttga tgcggttatc gactaccttc caagtccact tgacatccca gcaatcaaag
    18301 gtattaaccc agatacagac gctgaagaaa ctcgtccagc atctgacgaa gagccatttg
    18361 cagctcttgc cttcaagatc atgactgacc cattcgtagg tcgtttgaca ttcttccgtg
    18421 tttactcagg tgttcttcaa tcaggttcat acgtattgaa tacttctaaa ggtaaacgtg
    18481 aacgtatcgg acgtatcctt caaatgcacg ctaacagccg tcaagaaatc gacactgttt
    18541 actcaggtga tatcgctgct gccgttggtt tgaaagatac tacaactggt gactcattga
    18601 cagatgaaaa agctaaaatc atccttgagt caatcaacgt tccagaacca gttatccaat
    18661 tgatggttga gccaaaatct aaagctgacc aagacaagat gggtatcgcc cttcaaaaat
    18721 tggctgaaga agatccaaca ttccgcgttg aaacaaacgt tgaaactggt gaaacagtta
    18781 tctcaggtat gggtgaactt caccttgacg tccttgttga tcgtatgcgt cgtgagttca
    18841 aagttgaagc gaacgtaggt gctcctcaag tatcttaccg tgaaacattc cgcgcttcta
    18901 ctcaagcacg tggattcttc aaacgtcagt ctggtggtaa aggtcaattc ggtgatgtgt
    18961 ggattgaatt tactccaaac gaagaaggta aaggattcga attcgaaaac gcaatcgtcg
    19021 gtggtgtggt tcctcgtgaa tttatcccag cggttgaaaa aggtttggta gaatctatgg
    19081 ctaacggtgt tcttgcaggt tacccaatgg ttgacgttaa agctaagctt tatgatggtt
    19141 catatcacga tgtcgactca tctgaaactg ccttcaagat tgcggcttca ctttccctta
    19201 aagaagctgc taaatcagca caaccagcta tccttgaacc aatgatgctt gtaacaatca
    19261 ctgttccaga agaaaacctt ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg
    19321 tagatggtat ggaagcacac ggtaacagcc aaatcgttcg tgcttacgtt ccacttgctg
    19381 aaatgttcgg ttacgcaaca gttcttcgtt ctgcatctca aggacgtggt acattcatga
    19441 tggtatttga ccactacgaa gatgtaccta agtcagtaca agaagaaatt attaagaaaa
    19501 ataaaggtga agactaatcc gtcctcactc tagaaggaag tcacttagtg gcttcctttt
    19561 gtctttagaa aatacctcta aatatggtaa aatagtagaa gaataatgtg aggaaaatga
    19621 atgtcaaata gttttgaaat tttgatgaat caattgggga tgcctgctga aatgagacag
    19681 gctcctgctt tagcacaggc caatattgag cgagttgtgg ttcataaaat tagtaaggta
    19741 tgggagtttc atttcgtatt ttctaatatt ttaccgattg aaatcttttt agaattaaag
    19801 aaaggtttga gcgaagaatt ttctaagaca ggcaataaag ctgtttttga aattaaggct
    19861 cggtctcaag aattttcaaa tcagctcttg cagtcctact atagggaggc tttctctgaa
    19921 ggtccatgtg ctagtcaagg ttttaagtcc ctttatcaaa atttgcaagt tcgtgctgag
    19981 ggtaatcagc tatttattga aggatctgaa gcgattgata aggaacattt taagaagaat
    20041 catcttccta atttagccaa acaacttgaa aagtttggtt ttccaacttt taactgtcaa
    20101 gttgagaaga atgatgtcct gacccaagag caggaagagg cctttcatgc tgaaaatgag
    20161 cagattgttc aagctgccaa tgaggaagcg ctccgtgcta tggaacaact ggagcagatg
    20221 gcacctcctc cagcggaaga gaaaccagtc tttgattttc aagcgaaaaa agctgcagct
    20281 aaacccaagc tggataaggc ggagattact cctatgatcg aagtgacgac agaggaaaat
    20341 cgtctggtat ttgaaggggt tgtttttgat gtggagcaaa aagtgactag aacaggtcgt
    20401 gttttaatca actttaaaat gacggactat acttcaagtt tttctatgca aaagtgggtt
    20461 aaaaacgagg aagaggccca gaagtttgac ctcatcaaga agaattcttg gctccgagtt
    20521 cgagggaatg tggagatgaa taacttcaca cgcgatttga ctatgaacgt acaggatctg
    20581 caggaagttg ttcactatga gcggaaggat ttgatgccag aaggtgagcg tcgggttgag
    20641 tttcatgctc atactaacat gtcgactatg gatgctttgc cagaggtcga agagattgtt
    20701 gcaacagctg ctaagtgggg acacaaggcg gttgctatca cagaccatgg gaatgtccag
    20761 tcctttccac atggctataa ggcggctaag aaagcgggaa tccagctgat ctatgggata
    20821 gaagccaata tcgtggagga ccgtgtccct atcgtctata acgaagtgga gatggactta
    20881 tcagaagcaa cctacgtggt ctttgacgtg gaaacgacgg gactttcagc tatctataat
    20941 gacttgattc aggttgcggc ctctaagatg tacaagggga atgttattgc tgaatttgat
    21001 gaatttatca atcctgggca tcccttgtca gcttttacta cagagttaac tggaattaca
    21061 gatgatcatg tcaaaaatgc caaaccacta gaacaagttt tgcaagaatt ccaagaattt
    21121 tgcaaggata cggtcctagt tgcccacaat gctgcctttg acgttggctt tatgaatgct
    21181 aattatgagc gtcatggtct tccaaagatt agtcagccag ttattgatac gctggagttt
    21241 gctagaaacc tctatcctga gtataaacgc catggtttgg ggcctttgac caagcgtttt
    21301 ggtgtggcct tggaacatca ccacatggcc aactacgatg cggaagcgac tggtcgtctg
    21361 cttttcatct ttatcaaaga ggtagcagaa aaacatggtg tgaccgattt agctagactc
    21421 aacattgatc taatcagtcc agattcttac aaaaaagctc ggatcaagca tgcgaccatc
    21481 tatgtcaaga atcaggtagg tctaaaaaat atctttaagc tggtttcctt gtctaatacc
    21541 aagtattttg aaggagtgcc acggattccg agaacggttc tagatgccca tcgagagggc
    21601 ttgattttag gttcagcctg ttcagagggt gaagtttttg acgtggtcgt ttctcaaggt
    21661 gtggatgcgg cggttgaggt ggccaagtat tatgacttta tcgaggtcat gccaccggct
    21721 atctatgcgc ccttgattgc taaagagcag gtcaaggata tggaggaact ccagaccatt
    21781 atcaagagtt tgatagaggt tggagaccgc cttggcaagc ctgttttggc tacgggaaat
    21841 gttcactata tcgaaccgga agaagagatt tatcgtgaaa ttatcgtccg tagtttggga
    21901 cagggtgcga tgattaaccg aactatcggt catggtgaac atgcccaacc agcaccactt
    21961 ccaaaggctc attttcgaac gactaatgag atgttggatg aatttgcctt tttgggagag
    22021 gaactggctc gtaaactggt tattgaaaac accaatgcct tggcagaaat atttgaaccc
    22081 gttgaagtcg ttaagggtga cttgtatacg cctttcatcg acaaggctga agaaacagtt
    22141 gctgagttga cctataagaa agcttttgag atttatggaa atccgctgcc agatattgtt
    22201 gatttgcgga ttgaaaaaga attaacatcc atactgggga atggatttgc tgtgatttat
    22261 ctggcatcgc agatgctggt gcaacgttct aatgaacggg gttatttggt tggttctcgt
    22321 gggtctgtcg gatctagttt cgttgcgacc atgattggaa ttacggaggt caatcctctc
    22381 tctcctcact atgtctgtgg tcagtgtcag tacagtgagt ttatcacaga tggttcgtac
    22441 ggttcaggat ttgatatgcc ccataaggac tgtccaaact gtggtcacaa actcagtaaa
    22501 aacggacagg atattccgtt tgagaccttc cttggttttg atggggataa ggttcctgat
    22561 attgacttga acttctcggg agaagatcag cctagcgccc acttggatgt gcgtgatatc
    22621 tttggtgaag aatatgcctt ccgtgcggga acagttggta cggtagctgc caagactgcc
    22681 tatggatttg tcaagggtta cgagcgagat tatggcaagt tttatcgtga tgcagaagta
    22741 gaacgcctcg ctcaaggagc ggcgggtgtc aagcggacaa caggccaaca cccgggggga
    22801 atcgttgtta ttccgaacta catggatgtc tacgatttta cgcctgtcca gtatccagca
    22861 gatgatgtca cggctgaatg gcagaccact cactttaact tccacgatat cgatgagaac
    22921 gtcctcaaac tcgatgtact gggacatgat gatccgacca tgattcgaaa acttcaggat
    22981 ttgtctggta ttgaccctaa taaaattcct atggatgacg aaggcgtgat ggcactcttt
    23041 tctgggactg atgtgctagg ggtaacacct gaacaaattg gaacgcctac gggtatgttg
    23101 gggattccag agtttggaac aaatttcgta cgtggaatgg tagacgaaac ccatccgaca
    23161 acctttgcgg aattgcttca gctgtctggt ctgtcccacg gtactgatgt ttggttgggg
    23221 aatgctcagg atctgattaa gcaaggaata gcggacctat cgactgttat cggttgtcgg
    23281 gacgacatca tggtttacct catgcatgcg ggtctggaac ctaagatggc ctttaccatt
    23341 atggaacggg tacgtaaggg tttgtggcta aagatttcag aagaggagag aaatggctat
    23401 atcgaagcaa tgaaggctaa taaggtgcca gagtggtata tcgaatcctg tgggaaaatt
    23461 aagtacatgt tccctaaggc ccatgcggca gcctacgtta tgatggcctt gcgtgtagct
    23521 tacttcaagg ttcaccatcc tatttattac tactgtgctt acttctccat tcgtgctaag
    23581 gcttttgata tcaagaccat gggtgcgggc ttggaggtca tcaagcgcag aatggaagaa
    23641 atctctgaaa aacggaagaa caatgaagcc tctaatgtgg aaatcgatct ctatacaact
    23701 cttgagattg tcaatgagat gtgggaacga ggtttcaagt ttggtaaatt agatctctac
    23761 cgtagtcagg cgacagagtt cctcatcgac ggggataccc ttatcccacc atttgtagca
    23821 atggatggtc tgggagagaa cgttgccaag caactggtgc gggcgcgtga agagggagaa
    23881 ttcctctcta aaacagaact acgcaagcgt ggtggactct catcaacctt ggttgaaaag
    23941 atggatgaga tgggtattct tggaaatatg ccagaggata accagttgag tttgtttgat
    24001 gagttgtttt aaaaaattgc ttaataatct attaaaagag gctaacgtat atccaataga
    24061 tttacattag ctttcttttt tgttaaaata gtctatggaa agagggtgag agtatgtcaa
    24121 agatgagtat aagcatccgt ctggatagtg aggttaagga gcaggcccaa caggtgttta
    24181 gtaatctggg aatggatatg acaacagcta ttaatatttt ccttcgtcag gcaattcaat
    24241 atcagggatt accttttgat gttagactag acgaaaatcg gaagttgctc caagcgttaa
    24301 cggatttaga ccaaaatcgt aatatgagcc agtcttttga atcagtctca gatttgatgg
    24361 aggacttacg tgcttaagat tcgttatcat aaacagttta aaaaagattt taagttggct
    24421 atgaagcgtg gtttgaaggc agaattatta gaagaagttt tgaattttct ggttcaagaa
    24481 aaagaacatc ctgccagata tcgtgatcat tcattgacgg catccaagca ttttcaagga
    24541 gttcgtgaat gccataccca gccagattgg cttttggttt ataaagtaga caagtcggaa
    24601 ttgattttaa atttgctgag gacaggcagt cacagtgatt tattttaatc tattttaagg
    24661 gggttctcat gaaactaaga atatttgcgg aagataagcc ggctaagaag gtatttgaat
    24721 atcaattaga acttgctgat cgtacaattc ttctatcgac agcactcttg tcaggtgcta
    24781 ttgctttagc aggaatcttt tctgctttga aagaaaaata aaaatagaaa agagaaaaca
    24841 gaatggtttt accaaatttt aaagaaaatc tagaaaaata tgcgaaattg ttggttgcga
    24901 acggaattaa cgtgcaacct ggtcacactt tggctctctc tattgatgtg gagcaacgtg
    24961 aattggcaca tctaatcgtg aaagaagctt atgccttggg tgcgcatgag gtcatcgttc
    25021 agtggacaga tgatgtgatt aaccgtgaga aattcctcca tgccccgatg gagcgtttgg
    25081 acaatgtgcc agaatacaag attgctgaga tgaactatct tttggagaac aaggctagcc
    25141 gtcttggggt tcgttcatct gatccaggtg ccttgaacgg agtggacgct gacaagcttt
    25201 cagcttctgc taaagctatg ggacttgcca tgaagcctat gcgtatcgca actcaatcta
    25261 acaaggttag ctggactgta gcagccgctg ctggacttga gtgggctaag aaagtcttcc
    25321 caaatgctgc gagcgacgaa gaagcagttg atttcctttg ggatcaaatc ttcaaaactt
    25381 gtcgtgtcta cgaagcagat cctgttaagg cttgggagga acatgcagcc attctcaaga
    25441 gcaaggccga tatgcttaat aaggagcaat tttcagccct tcactacaca gcgccaggaa
    25501 cagatttaac acttggtttg ccaaagaacc acgtttggga atcagctggt gctgtcaatg
    25561 cacagggcga agaattcttg ccaaatatgc cgacagaaga ggtcttcaca gcgcctgact
    25621 tccgtcgtgc agatggttat gtcacttcta caaaaccgct tagctacaac ggaaatatca
    25681 ttgaaggcat taaggtgacc tttaaggatg gacaaatcgt agatatcact gctgagaagg
    25741 gtgatcaggt tatgaaagac cttgtctttg aaaatgcggg tgcgcgtgcc ttgggtgaat
    25801 gtgccttggt accagatcca agtccaattt ctcagtcagg cattaccttt tttaacaccc
    25861 ttttcgatga aaatgcgtca aaccacttgg ctatcggtgc agcctatgcg actagcgttg
    25921 ttgatggagc ggagatgagc gaagaggagc ttgaagctgc agggcttaac cgttcagatg
    25981 ttcacgtaga ctttatgatt ggttctaacc aaatggatat cgatggtatt cgtgaggatg
    26041 gaacgcgggt acctcttttc cgtaatggga attgggcaaa ttaaggagat aatatgttag
    26101 gaagtatgtt cgttggtctc ctagtgggat ttttagcagg tgctatgacc aatcgtggag
    26161 agcgaatggg atgttttgga aaaatgtttc tcggttggat cggagccttt ctaggtcact
    26221 tgctctttgg aacttggggg ccagttttat caggaacagc tattatccca gcgattttag
    26281 gagccatgat tgttttagct attttttgga gacgaggaag ttaatttcct aaatctgata
    26341 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa agcactgctt
    26401 tgaggttgca gatagaactg acgaagtcag ctaaaaacac tgctttgagg ttgcagatag
    26461 aactgacgaa gtcagctaaa aacactgctt tgaggttgca gatagaactg acgaagtcag
    26521 ctaaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tatatacggc
    26581 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt atgaaacgaa aaggaggttg
    26641 gtcattgtac tagcctcctt ttgatatgat ataatagttc tatgagatta gataaatttt
    26701 tagttgcctg tgcggtggga agtcggactg aggtcaaaaa cttgctcaag gctgggcgcg
    26761 tgactgtaaa tggtaaaaaa gaaaaatcag ctaaattgca gattgatgaa aaaatagatg
    26821 agattcgctt tgatgggcaa gtgttggagt atgaagagtt tgtctactac atgatgaaca
    26881 agcccaaagg agttatctca gcgactgagg atcccaagca cagaaccgtt ctggacttgt
    26941 tggatgactt ggcgcggagt aaggaagttt ttccagtagg acgcttggat attgacacgc
    27001 atggtctttt gctcttgacc aataatggtc agctggctca tgttcttctt tcgcccaagc
    27061 gtcatgtgga caagacttat caggctcagg tcaagggaat tatgacccaa gaagatgtgg
    27121 agacatttat caagggcatt ccgctcaaag actttacctg tcagcccgct agactggaga
    27181 ttctttccac agatgcagaa aagaatcaga gccaaatccg tgtgaccatt gcagaaggga
    27241 agtttcatca gatcaagcgt atggtgggct actgtggcaa ggaagtggtg gacttgcaac
    27301 gattgactat gggaacttta gtattagatg agaacctgga acgaggggaa tggcgtcgct
    27361 tgaccaagga agaattagaa attctccgcg ctaatattat ttaatttagt ttaatactca
    27421 atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt acggcaaggc
    27481 gacgttgacg tggtttgaag agattttcga agagtataaa ttcgaaaaag gtgagggaga
    27541 atgtccttac cttttatgtt ttttagttgc ttcctttgtg aaaagagtta taatagactg
    27601 tagaataaaa ggaggaatct atgaacgcga ttcaagaatc atttactgat aaactatttg
    27661 ccaactatga agcaaatgta aaataccaag cgattgaaaa tgctgccagc cacaacggaa
    27721 tttttgcagc tctggaacgt cgccaaagcc atgtagacaa cacacctgtt ttctcattgg
    27781 atttaaccaa ggacaaggtc actaaccaga aagcgtctgg tcgttgctgg atgtttgcgg
    27841 ctctcaacac cttccgccac aaactcatct cgcaatacaa attggagaac tttgagttgt
    27901 cacaagccca cactttcttc tgggataagt atgagaaatc aaactggttc ttggagcaag
    27961 tcattgcgac ttcagaccaa gaattgacta gccgcaaggt tagcttctta ctccaaacac
    28021 ctcaacaaga tggtggtcaa tgggatatgg tcgtttccct ctttgaaaaa tacggtgtcg
    28081 tgcctaagtc agtttatcct gagtctgttt catctagcag cagtcgtgag ctaaatgcga
    28141 tccttaataa attgcttcgt caagatgctc aaatcttgcg tgatttgctt gtttctggtg
    28201 cagatcaagt gactgttcaa gctaagaaag aagacctctt gcaagaaatc tttaactttc
    28261 ttgctatgtc attaggactt ccaccacgca agtttgactt tgcttatcgc gataaagata
    28321 acaactacaa aagtgaaaaa ggaatcacac cacaagagtt ctacaagaaa tatgtcaatc
    28381 ttcctttaga agactacgtt tctgttatca atgctccaac tgctgataaa ccttacggaa
    28441 aatcttacac agttgagatg ttggggaatg tggttggtag ccgtgcagtt cgttacatca
    28501 acgttccaat ggagcgcttg aaagaattgg cgattgccca aatgcaagca ggtgagactg
    28561 tttggtttgg ttctgatgtc ggccagctca gtaaccgtaa ggctggaatc cttgcgacag
    28621 atgtttatga ctttgaatca agcatggaca ttaaacttac tcaagacaag gctggacgtt
    28681 tggactatag cgaaagcttg atgacccacg ccatggtctt gacaggtgtt gacttggacg
    28741 aaaatggtaa atcaaccaag tggaaggttg aaaactcatg gggagacaag gtcggtacag
    28801 atggttactt tgttgcctca gacgcttgga tggacgaata cacataccaa atcgttgttc
    28861 gtaaggaatt gctgacagca gaagaacaag ctgcctatgg agcagaacca attgtacttg
    28921 caccatggga tccaatggga gccttggcta aataaaagca tagaaaaaag gaatcagatt
    28981 ttagaacctg gttccttttt agttgcttga ttacatgatg tgaagaacat gtgccacaat
    29041 acccactgcg aagagggcaa ggataatagt gattggagat acttttttct taagtaagta
    29101 catgcaaagt aaagtaagga gtagtcctga taatccagga atcaacatat ccaagttttg
    29161 ttggaaagta gtaacttttt caggagtttg agacaatcct tgtcctactt gtgcgaatgc
    29221 ttcttggata cctttagacc cttctggcaa tttatcccaa tggatataag ccttttcatc
    29281 tagttgaact ttagaaacat cgaaagcaaa tttaatattt acccagcgtt gaacaaggac
    29341 agcaagaatg aacatcccaa ggatagaagc tcctttagtg atatcttgaa ggataccacc
    29401 agacatatct ttagtgattt ctgatccagc cttgtatcca atctcttgaa cataccacaa
    29461 gaatgacata cgaatcaagt tccatgcaac aaagaagagg agtggcccca agatattgcc
    29521 agtaagggca agtgaagcac cgagagatcc aaggattggg cgtactgtaa accagaatac
    29581 tgggtcaccg ataccagcaa gaggtcccat cataccgatt ttaacccctt ggatagcagc
    29641 gtcatcgatt tccacaccgt tagcacgttc ttcttcaagc gcaagagtaa cccccatgac
    29701 tggagcagct acgtatggat gagtgttgaa gaactcaagg tgacgctcaa gagcagcgat
    29761 ttgatcttct tttttagtat agagtttttt gatagctgga atgagtgtat aagcccagcc
    29821 caagttttgc atccgttcaa agttccaaga cccttgtaag aaggttgaac gccaccaaac
    29881 ttttttacga tctgatttag ttaattgaag tttttcagtc atgatgtttt cagtcctttc
    29941 ttatcttagt agtcttctag gatatcgccg attgggtcgt tagaagttgc ggctcctccg
    30001 ccaccatttc caccagtttt agaaaggtga aggtagataa gagcgatagc aacaccgata
    30061 gcaccgaatc cgattagagt aatatctgac acagcagcga gaacgaaacc aagagcgaag
    30121 aatggccata cttcacgagt tgccatcatg ttgataacca tggcgtaacc aacggcaacg
    30181 accataccac caccgatagc cataccatct ttgagccagt ctggcatggc actaaggata
    30241 ctttgtacag tttcagttgg taccataagg agaagagctg caggaagcgc gatacgaagt
    30301 ccttggaaga gtagcgcaat gaaatgcgca cgctccacag cgccgaagtc acctttttta
    30361 gcggcagcat ctgcagtatg aaccaaacca actgaaattg tacgaacaat cattgtcaag
    30421 aaaagtccag ctacggcaag agggatagca accgcttggg caacaccgat accagtcttg
    30481 gtaaagtcac caccaagaac catgataatg gcagcagcga cagaagcaag tgcagcatca
    30541 ggagcgatag cagcaccgat atttgaccaa ccaagggcaa tcatttgaag cgatccaccg
    30601 aggataatcc ctgcttccaa gtgacctgtt acaagcccaa taagggtaca ggctacaagt
    30661 ggttggtgaa attggaactg gtcgaggatg ccttcaagac ctgcaaagaa ggctacaacg
    30721 actactaaaa ccatagaaat aatagacatg tttaaaatcc tttcataaat aatggcttat
    30781 ttgacattgg ctttgttaat caagtcaaac aaatcttttt tagaatcatt tggtacttta
    30841 cggacatcaa attcaacacc caagtcacgc attttttcaa atgtagcaac atcttctttg
    30901 tccatagaca aaacggtatt gaccaatgtt ttacctgttg agtgagccat agaaccaacg
    30961 ttaagagtct tgattggcac gccgccttcg atggcacgaa gggcatcttg aggtgtttca
    31021 aacaagataa gggcatgtgt ttctccaaaa cgtgggtctt ttgaaatctc aatcagtttt
    31081 tgaattggaa ccacgttagc cttgacatta cctggagctg cttgtttaat caattcttta
    31141 cgaaggtcgt ctttagccac gttatctgaa gcaacgatga tacgatttgc ttttgaatct
    31201 ggagtccaag cagttgcaac ctgaccgtga agtagacgtg tgtcaagacg ggcaagattg
    31261 attttcaatt taccgtctcc gataacagtt ccttctggga tagcagtttg ggcaactgga
    31321 gcagctgcag cgcttgcaac ttcttcaact ggatttagct cttctggaag agctttgatg
    31381 ccatctttgg cttctttaat gatattagca gcgacttttt ctacacctgc agcagcgtcc
    31441 atgaggcgct ctgtgtaggc ttgaatcaac atcggtaagt taagtcctgt gatgatggca
    31501 aacttacgct caggattttc tcccatcacg cgactagctt ggttaaatgg agaaccactc
    31561 caaaggtcag ccaaaactag aacctcatct tctgcgtcaa atgcagcaac agcgttatta
    31621 aacttagcgt atagatcatc aggaccttca tttggcataa aggtcacaac ttgaaccttt
    31681 tcttgttcac caaagatcat agatcctgac tgatgaatac ccgcagcaaa ttcgccgtgg
    31741 ctcgcaataa tgattccgat actcattatt gtcattcctc cttttttgtt ttagttttca
    31801 tttaagaaaa ctttaagact gtttaagtat aaaccgtttt cataaaaaaa gcaactattt
    31861 atcataaaaa attaaaaaat ttttattttt gtatgttgat atgttgagtt tttgaggagt
    31921 aatcttgaat tcttatttaa aatttaatat aaaaaagttg gaagaagctt ccaactttta
    31981 aaataggttt ctattagatt agtgggtgaa gtcgagtacc atacgtcctt ggatttggcc
    32041 tttttccatt tcgtcgaaaa tggcaacagc atcttctact ggacgttttt gaacaactgg
    32101 gactaccaga ccttctgcac caaattggaa ggcttcttct aagtctttac gagttccgac
    32161 aagagaaccg atgacttgga ttccatcgag gactgtttta acgatgctga gttccatcat
    32221 ttcagaagga agaccaacag cgacgacgcg accaccagca cgaatggagt caacagcctg
    32281 gttgaaggca actttagaca cagcagttac gacagctgaa tgagctcctc catcagtttt
    32341 ttctttaatg agtccagcta catcttcaac ttcgaggccg ttaatcacaa tgtcagcgcc
    32401 tacttctttt gcaagggcaa gtttgtcatt gttgatatcg actgcgataa catgagcatt
    32461 gaatactttt ttagcgtatt gaacagcgag gttaccaagt ccaccagcac cgtaaagaac
    32521 agcccattgg cctggttcaa cttttgcttc tttgatagct ttataggttg ttactccagc
    32581 acatgtgata gaagaagctt gggctggatc aagtccgtca ggaactttga cagcatagtc
    32641 agcagttacg atacattgtt cagccatacc accgtctact gagtagccag catttttcac
    32701 tgtacggcaa agggtttcgc gaccagttgt acagtattcg caagtgccac atccttcaaa
    32761 gaaccaagca acgctgacgc ggtcaccgac tttaaggctt ttcacatctg gagcaatctc
    32821 tttaacgata ccgatacctt cgtgcccaag aacacgtcct gggacttgac caaagtcacc
    32881 atgagcaacg tggaggtcgg tgtggcaaac gccacagtat tcaacttcta caagtgcttc
    32941 cccagtttca agtggacgga gtactttttc ttcaatagca acaccagtgc tttctggatt
    33001 tacaacaaca gctttcatag ctatcctcct tgatattgac cgagaacagg gacaacggga
    33061 ctggattgat tttttgtcaa cagagtcgag tgtgacgagc tctcttgtat ttatatgtga
    33121 agtatatcac aaaagaaagc cttttccaag gttttggaga caaaaagtag aacaatcgat
    33181 taactggttg atgagactgt gaaaagagca caaagaccag cttgcaagct ggtcatactc
    33241 ttcgaaaatc tcttcaaacc acgtcagctt catctacaac ctcaaagcag tgctttgagc
    33301 aacctacggc tagcttccta gtttgctctt tgattctcat tgagtatcag tataggttat
    33361 aagaataagt tataagaata agtcttgtag ggttttggca accccatctt ggtcgttggt
    33421 aagggaaatt tgctcatctg cataagggag tagctctgga ttggcatttt tcatggcata
    33481 acccttccca gcaaaagcga gcatttcggt atcattgtgt tcatctccaa aggcaatcaa
    33541 atcttttttg tcacgattca ttatcttgag caagtagtcc aaagcaaagg ccttgttgac
    33601 accttttggg gtacattcaa ggatattgag cggacctccc caggtattga tagaaagttg
    33661 atgctggtag aaggcgttca tttcttttgc caaggcatat ttgtcactgg ctctggtctg
    33721 caagaggata cagttagggt ccttggtcac caattcaggc tggaattgat cttcaggctg
    33781 gaaagcttct acaccaaata gtttgggatt ggcaatttct tcattgggat ttgtaatgta
    33841 gaatttttta cgatattctc cagcgataaa atcggcttga atgtcctctg aacgttgaac
    33901 catatctagc agatattttt tgtctacagt caaacacttt tcaaaatccc aaacttggtc
    33961 tggtaaatga gtaagggatc cgttgaagtt aatcatagga gtgtctaagc ccagttcacg
    34021 gtaaaaatct tttgacatac ggtaagggcg acctgtcgta ataataacct gatggccttt
    34081 ttcagcaact tttttgatgg tttttttggt aaagtcagaa atttgactgt ctgagttgag
    34141 cagggttcca tctaggtcaa ctgcaataat ttttttcgtc atatggacct ttctagtgtg
    34201 ttttcagata agatgtcttc tattataaca gaaagcaggc agaaaagcag attccaaaca
    34261 aaaaatgaaa ttggattaat ttcttaaaca aatcaaacaa agacattgaa aaagtgaatg
    34321 ataaatgata taattctatt attgttcgta aaaattaaaa ggagattgat gatggacaaa
    34381 ttatttaaac taaaagagaa cggtacagac gttcgtacag aggttctcgc tggtttaaca
    34441 actttctttg caatgagcta tattctcttt gtaaacccac aaattctttc gcaaacagga
    34501 atgcctgctc agggtgtgtt tcttgcaacg attatcggtg cagttgctgg taccttgatg
    34561 atggccttct atgctaactt gccatacgct caagcaccag gtatgggact caatgccttc
    34621 tttaccttta cagtcgtatt tggacttggt tattcatggc aagaagccct agctatggtc
    34681 ttcatctgtg ggattatttc attggttatt accttgacaa atgttcgtaa aatgatcatt
    34741 gaatcgattc caaatgccct tcgctcggct atttcagctg gtatcggtgt cttccttgcc
    34801 tatgtaggga ttaagaatgc tggacttttg aaatttacga ttgatccagg caactatact
    34861 gttgtaggag aaggggctga caaagctcaa gcaacgattg cagcaaactc ttcagcagtt
    34921 ccaggcttgg tcagctttaa taatccagct gttttagtgg ctcttgcagg acttgccatt
    34981 actatcttct ttgtcatcaa agggattaaa gggggaatta ttctctctat cttgacaaca
    35041 actgttcttg ctattgcagt tggtttggtt gatttgtcta gtatcgattt tgctaataac
    35101 catgttggtg cagcttttga agatttgaag acaatctttg gtgcagctct tggttcagaa
    35161 ggtttgggag ctttggtttc agatacagct cgcttgcctg aaactctgat ggccattctt
    35221 gccttctcat tgacagatat ttttgacaca attggtacct tgatcggtac aggtgaaaaa
    35281 gttggtattg tagcgacaaa tggtgaaaat caccaatcag ccaaattgga taaggctctt
    35341 tactctgatt tgattggaac gacagtcggt gccattgcag gtacttcaaa cgtaacgact
    35401 tatgttgagt ctgctgctgg tatcggtgca ggtggacgta ctggtttgac agccttggtt
    35461 gtagctatct gttttgcgat ttcaagcttc tttagcccac ttctagcgat cgtaccaaca
    35521 gcggctacag ctccaatctt gattatcgtt gggattatga tgcttggtag cttgaaaaat
    35581 atccattggg atgatatgtc tgaagcagtt cctgccttct tcacatctat ctttatggga
    35641 ttcagctact ctatcactca agggattgca gttggtttct tgacttacac tttgactaag
    35701 cttgtcaaag gtcaagttaa agatgttcat gccatgattt ggattttgga tgccttgttt
    35761 atccttaact acatcagcat ggccttataa tagaatgacc cagggggatt tccccccttt
    35821 tttaatacaa aggagatagg tgatgaaaga gaaaaatatg tggaaagaat tgttgaatcg
    35881 tgcaggctgg attttggtct ttttacttgc cgtcctttta tatcaggttc ccctagtggt
    35941 tacctctatt ttgactttaa aagaagtagc cctgctacag tcagggctga tagttactgg
    36001 cctttcaatt gtggttctgg ctctatttat tatgggagct cgtaaaacca agttagctag
    36061 ttttaatttt tcttttttta gagctaaaga tttggcacgt ttgggcttga gttatttagt
    36121 tattgtcggg tcaaatatac ttggttctat cttgttgcaa ctgtcaaatg agacgacaac
    36181 agctaaccag tctcagatta acgatatggt tcagaatagt tctctgattt ctagcttctt
    36241 cttgctagcc ttgcttgctc caatttgtga ggaaatcttg tgccgtggga ttgttcctaa
    36301 aaagattttc cgaggcaagg agaacttggg atttgtagtc ggtacgattg tgtttgcttt
    36361 attgcatcaa ccaagtaatt taccttcttt attgatttat ggaggtatgt cgacagttct
    36421 atcttggacg gcctacaaga cccaacgttt ggaaatgtcg atcttgcttc acatgattgt
    36481 taatgggatt gctttctgtt tgttggctct tgtggtgatt atgagtcgga cattaggaat
    36541 ttctgtttaa aagtttttat gtaggaaccg acctctttct actagggaaa gatgaatgca
    36601 atcgtgtcca tctttttctt tttatggtaa aatagaaaaa taatatgatg aaaatccttg
    36661 agggagtgac cgatatgtca agtaaagcta atcatgcaaa gacagttatt tgcggaatta
    36721 tcaatgtaac cccagactcc ttttcggacg gtggtcaatt ttttgctctt gagcaggcac
    36781 tccagcaggc tcgtaaattg atagcagaag gagccagtat gctcgatatc ggcggagaat
    36841 cgactcggcc gggaagtagc tatgttgaga tagaagagga aatccagcgt gttgttccag
    36901 tgatcaaagc gattcgcaag gaaagtgatg tcctcatctc tattgatact tggaagagtc
    36961 aagtagcaga ggctgctttg gctactggtg ccgatctagt caatgatatc actggtctca
    37021 tgggtgatga aaaaatggcc catgtggttg ctaaagctgg agcgaaagtg gtcatcatgt
    37081 ttaacccagt tatggctcga cctcagcatc ctagttcgct tatcttccct cattttggct
    37141 ttggtcaaac ctttacagaa aaagagttag ctgactttga aacattgcca atcgaagact
    37201 tgatggtggc tttctttgaa cgagcactag cgagagcggc agaagctggt attgcaccag
    37261 aaaatatcct gttggatcca ggaattggct ttggtctgac caagaaagaa aatcttctcc
    37321 ttttacggga cctggataaa ctacatcaga agggctatcc aatctttctc ggagtgtcgc
    37381 gcaagcgatt tgtcatcaat atccttgaag aaagtgggtt tgaagtcaat cctgagacag
    37441 agcttggttt ccgaaatcgg gacacggctt cggctcatgt aactagtatc gctgcgagac
    37501 agggtgtaga agtggtgcgc gtgcatgacg tagctagtca caggatggca gttgaaattg
    37561 cctctgccat tcgtctggct gatgaagcgg aaaatttaga tttaaaacaa tataaataag
    37621 atgaaagaaa ttgaaaacaa tcagtggatt gctaactacc ggacggatca accgcatttt
    37681 ggcttggaac gaatggtgga actgttagct ttgcgtggca atccccatct taaactcaag
    37741 gttctccata tcggagggac taacggcaag ggctcgacta ttgctttttt gaaaaagatg
    37801 ctagaaaagc tagggctgag agttggcgtg tttagttcgc cctatctcat tcattacaca
    37861 gaccagatta gcatcaatgg ggaatcgatc tcagaagcga ggctagaagc tctcatggca
    37921 gactatcagt ctttgctgga gggagaagcg gtcgccaatt tacagggcac aaccgagttt
    37981 gagattatca cagccctagc ctatgactac tttgcctcag agcaagtaga tgtggctatc
    38041 atggaagttg gcatgggtgg acttttggat agtaccaatg tctgtcagcc cattttgaca
    38101 ggaattacaa ctattggctt ggatcatgtg gccctacttg gtgacacctt ggaggccata
    38161 gcagagcaga aggcaggtat tatcaaacaa gggatgccct tggtaacagg gcgtattgct
    38221 ccagaagcct tgactgtgat tgaccgcatt gcggaaggga aagatgcgcc gagacttgcc
    38281 tacgggacag attatcaggt tcgtcatcaa gaaagtgtgg tgacagggga agtctttgac
    38341 tatacaagtg ctgtcagaca aggtcgcttc cagactagcc tgcttggttt gtaccaaata
    38401 gagaatgctg ggatggccat agctttactt gatacttttt gtcaagaaga tggtcgagag
    38461 ctagcaagca atgactttct tggtcaagcc ttggaagaaa caagttggcc agggcgtttg
    38521 gaaatcgtgt caagagatcc cttgatgatt ttggatggag cccataatcc ccatgctatc
    38581 aaggccttgt tggtaacctt gcaagaacgt tttgcggatt atcataagga aatcctcttc
    38641 acttgtatca aaaccaaagc cttgggggat atgttggact tgctgggagc catgccagat
    38701 accgagctta ctctaacaca ttttgcggat agtcgggcga cggatgaaag cgtgctgaaa
    38761 gaggcagcta agtctagaaa tctcagctac caagattggc atgattttct agagcagaat
    38821 ttgacagata aaaaagaaga gaaacaaaca gttaggattg tcacaggttc cttgtatttc
    38881 ttgagccaag tgagggccta tctgatggag aggaagaacg agaatggata cacaaaagat
    38941 tgaagcagct gtaaaaatga ttatcgaggc tgtaggagag aacgctaatc gcgagggctt
    39001 gcaggaaaca cctgctcgtg tagcccgtat gtatcaagag attttttcag gtcttggtca
    39061 aacagcagag gaacatttgt caaaatcctt tgaaattatt gacgataata tggtggtaga
    39121 aaaggatatc tttttccata ccatgtgtga acaccacttc ttgccatttt atggtagagc
    39181 gcacattgcc tacattccag atggtcgtgt ggcaggcttg tctaagctag cccgtacggt
    39241 tgaagtttat tcgaaaaaac cacaaattca agaacgtttg aatatcgaag tggccgatgc
    39301 cttgatggac tatctaggtg ctaaaggagc ctttgttgtc attgaggcgg aacatatgtg
    39361 tatgagtatg cgtggtgtta gaaaaccagg cactgcaacc ttgacgacag tagctcgtgg
    39421 tctatttgaa acagataagg acctccgcga ccaagcttat cgtttaatgg ggctataaaa
    39481 agaatccgtt tcaagcggat ttttctagaa aggaatcatt atggatcaac tgcagattaa
    39541 ggatttggaa atgtttgcct atcatggtct ttttcctagt gagaaagaat tggggcagaa
    39601 atttgtcgtt tcagccatcc tatcctatga tatgaccaag gcagctacag acttggattt
    39661 aacagcctct gtccattacg gagaattgtg tcagcagtgg acgacttggt ttcaggaaac
    39721 gagtgaagat ttgattgaaa cggtagccta taaactggtg gaacgtacct ttgagtctta
    39781 tcctcttgtc caagaaatga agttggaact gaaaaaacct tgggcaccgg tgcatttgtc
    39841 actagatact tgctcggtaa ccattcatcg ccgcaagcaa cgagccttta tcgccctagg
    39901 aagcaatatg ggagataaac aagcaaactt gaagcaagcc attgacaaac tgcgagctcg
    39961 tggcatctat attctcaaag agtccagtgt cttagcgacg gagccttggg gtggagtgga
    40021 gcaggatagc tttgccaatc aagtggttga ggtggaaacc tggctaccag cacaagactt
    40081 gttagaaacc ttgttagcca ttgagtcaga gctgggacgg gtgagagaag tgcattgggg
    40141 acctcgtttg attgatttgg acttgctctt tgtggaggac cagatccttt atacagacga
    40201 cctcatattg cctcatcctt acatagcgga acgccttttt gtccttgagt ccttacagga
    40261 aattgcgcct cattttatcc atccgatatt aaaacaaccg atccgtaact tgtatgatgc
    40321 tttgaaaaaa tagaaaaact ctagttttca gttacttgca actgaaggct agagttttta
    40381 aaataggtca ttttcttctg ggaggaggat agtttctcta ccgtccatgt ctaaaaccag
    40441 tactcttggg ggataacgag ggtcgaaagg atggttaaag tcaaaatcaa tggctgtagg
    40501 gaggtgttga cttgaaaagt ggaaggtaat ctttccttgg ttattaagca attgaaactc
    40561 gagttcttct tccaattcaa agacattttt taagaaatgg tcgataatat accaaaaaga
    40621 gtcaatgatg tcatcaggca agctggtaac aatgccaaaa ctagcagacc gcatgtgggt
    40681 attggtaaaa gccatatctc tgtctccttt cttttccctt atcatacagc aaataggatt
    40741 aaaaatcaag aaaaggtgat tttttgaaaa ggattttaac tacagggaaa aagaaggaaa
    40801 aaaattccca aaaatctacc gaagttaata ggtaaattcc caaattaact tgattatata
    40861 actttcagtt attttgagaa gttaccgaaa aatatttttt atatctattg acttttaggg
    40921 gtgaaatttg gtatgatagt aggcggtatt gtttacccca tttgaaaggc cccggaacct
    40981 tccaaatact tttcgatggg aaggaacacc catcaccgta aacaaaaatc gaactatata
    41041 taggagaaat catgaacaaa acaacattta tggctaaacc aggccaagtt gaacgtaaat
    41101 ggtacgtagt tgacgcaact gatgtaccac ttggacgtct ttctgcagta gttgctagcg
    41161 tacttcgcgg aaaaaacaaa ccaacattta caccacacac tgatacaggt gacttcgtga
    41221 ttgttatcaa tgctgaaaaa gttaaattga ctggtaaaaa agcaactgat aaaatctact
    41281 acactcactc aaaccaccca ggtggattga aacaaatctc tgcaggtgaa cttcgttcta
    41341 aaaatgcagt acgtttgatt gagaaatcag ttaaaggtat gcttccacac aatacacttg
    41401 gacgcgctca aggtatgaag ttgaaagtat ttgttggagc tgagcacact cacgctgcac
    41461 aacaaccaga agttcttgac atttcaggac ttatctaagg aaaggaacaa taaagtatgt
    41521 cacaagcaca atatgcaggt actggacgtc gtaaaaacgc tgttgcacgc gttcgccttg
    41581 ttccaggaac tggtaaaatc actgttaaca aaaaagatgt tgaagagtac atcccacacg
    41641 ctgaccttcg tcttgtcatc aaccaaccat tcgcagttac ttcaactgta ggttcatacg
    41701 acgttttcgt taacgttgta ggtggtggat acgctggtca atcaggagct atccgtcacg
    41761 gtatcgctcg tgcccttctt caagtagacc cagacttccg cgattcattg aaacgcgcag
    41821 gacttcttac acgtgactca cgtaaagttg aacgtaagaa accaggtctt aagaaagctc
    41881 gtaaagcatc acaatttagt aaacgttaat tcgaaagaat tactatactt atacagagca
    41941 cctttcgggg tgttcttttt ttatactttc ttactaaatt ggtgcaattg acacagttgt
    42001 tgcgacttta gtcgcttaca aatgtggctg caacctgaca aggtcagttg cctcaaaacg
    42061 ttaatcaata caattatatc aacgtttcaa agcactcaag agtttacctc atgggtgctt
    42121 tttttatgtt ttttgaaaaa gttcacctca aagtttacct tattttcacc ttattgtttt
    42181 agagactgta aggcaaattc accgacggcc atagggacta cattagaagt attgacataa
    42241 atctgtgttg tacctgtgtc gctatgtatt agagcttcag aaatggcttc taagctcatt
    42301 cctgcttgtt tagcgagcgt tgctccggta tgacgtagtt tgtgtggcgt agcgtgtgta
    42361 agctctgggt gtcgttttct gatagttttc atcttattat tgagatagtc agaatgtaaa
    42421 ggtttattga tattgccttt ggtatctatg taagtaaaga tgaattgttc tggattactg
    42481 atgataccaa actttgccag ttcatatttt tgttgttttt tccatgaagt cagaagttga
    42541 agtaagtcat tagaaataga gaaaatggga aatgtttcca caataaaacg catattatca
    42601 gatggttaat gcgttttata tttgggtttg aggcttataa aataggataa gcgtactgaa
    42661 aacttagata tgacaaacaa aataaaattt ttaaaagcta catagaaaca tggtataatg
    42721 tatctaaagg aggtagcata tgtccttaga tatagataaa gaaaagatga caatcatggg
    42781 aatagctttt gaaaaccgat ccgtttttaa gagtgtttgg tatgctttaa gtacaaatat
    42841 gattgaagga tggcgaccta cggttagtga tgttgaaaaa ttacgagatg aagctcttgc
    42901 tctggggatg acttaatgaa gcgcaactgt tatgaatctt atgactatgt tgatccggat
    42961 aatttatata ccgatccggg ttcttcagtt ctaagaaata agcaggaagg aaaaaagcac
    43021 gcgagcttga atatcgtatg attgctagta agagtttgaa attatttatc aatcctatct
    43081 tagttaatag tttaaaagta gtttgtttca caactgcata agcttagaaa agttgaaaag
    43141 tgataactct ttaataaact cttggtttgt taaaagatat tttgtccact acattttttt
    43201 caattgacta ttatttgtca tagatataac agatagaaca ttgcattcag aataatgaaa
    43261 aacgcatcaa aaatggtgcg ttctgttttt atgctaccat aaaaggagga aaacaaattg
    43321 aaaattttta agggagagtt ttatcgaatc tctgtattaa cagacaagct agtaaggtta
    43381 gaatactctc gaactggaaa ttttgaggat agaacgacac aacttatcta taatagagat
    43441 tttggccaag tttcgttaga ttatatcgag acatcaaatg tactagatat tatgacggac
    43501 tattttcatc tgcactttaa taaaggagaa tttaacgccg aaaatttatt tatagaatta
    43561 aaaggaaatt ttgccgtata tggtagtcgc tggtattttg gtgaatctat tgaaacgtta
    43621 aaaggaacag ctcggactct ggataaggca gatggagcaa tctcgttaga agatggaatt
    43681 attagccgaa atggtatagc cttattggat gattctcaag gatttatttg ggatgaacaa
    43741 tctggttata ttgagagaga aaatcaaatt gacctgtatt tctttgccta tgggcatgat
    43801 tatagaggag caatcagaga cttttaccat ttgactggtt caacaccctt gttgccaaga
    43861 tatgctttag gcaattggtg gagtagatat tggccttata cgtcggatga atacttggat
    43921 ttaatagaca gatttgaaac agagaaaatt ccattatcta tcggtgtgtt agatatggat
    43981 tggcatataa ctgacattcc agctcgtttt ggaagtggct ggacaggata tagttggaat
    44041 agaaacttaa taccaaatcc agaacagtta ttgcaacaac ttcatgatag aaagttaaaa
    44101 ctctccttaa atgtccatcc tgctgatggg atacgggctt atgaagaagc ttatcctcaa
    44161 atcgcaaaac gattggggtt aaatgtagaa ctagaagaac ctgctatttt tgattttttt
    44221 aatccctctt ttagggaagc ctactttaaa gatgttcatt atgagttaga aaagcaggga
    44281 gtagattttt ggtggattga ctggcaacaa gggacacaag gtatgctaga tccactttgg
    44341 cttttaaacc attatcacta tcaggatagt tgtaaaaatg cagaaggtgg tttgatttta
    44401 tcaagatatg caggtcctgg tagtcaccgc taccctgttg gtttttcagg ggatactatt
    44461 attagttgga attccttaag atttcaaccc tattttacag cgacagcatc taatatcggt
    44521 tatagttggt ggagtcatga tatcggtgga catatgttgg gggattatga cgaagagcta
    44581 caaactagat ggctacagtt tggtgttttt agtccgatta ctcgattaca tagttctaga
    44641 agtcctttta atagtaaaga accttggttt ttttcagaaa caacatctaa gattatgaag
    44701 aaatacctcc gtttgagaca tcagatgatt ccctatctat ataccatgaa tgtaaagaca
    44761 catgaggaag gtgccccatt aatcagtcca atctattatt tctatccaga gaatgatgag
    44821 agctataatg ttccaaatca atactttttt ggaacagaac tgatggtggc tcccattgta
    44881 gaaaagatgg atttgacatt ccaatctgca aaagtagatg tatggttccc tgaaggtgaa
    44941 tggtatgact ttttttcaga gaaaaaatac acaggtggtg tgaagttaag tgtttataga
    45001 gacatctcga ctacgcctgt gtttgcaaaa agtggtgcaa tcattccctt ggttggttct
    45061 gagataggta tgggtgttga tttacctgaa gttgtagatt ggtatgtatt cccaggaaaa
    45121 caacattctt ttgaaatgct tgaagatcaa aatggtcaaa gatataaaac aagattatca
    45181 atcgattggg aaatgggaat ggtagagtta gcattacaag gagattctag tatcgttcca
    45241 agcaatagaa aacatagaat tcattttaaa ggaacgaatg tgtctataat tgaattgcca
    45301 aataagaatg atacagctaa atttgaatgg aaagataata aaaggacatc tttaaatgac
    45361 gaagttttta gactactaaa gacagcttct cttccatatg aattaaaaga tagattgtta
    45421 aatcaattca tcaatgcgaa aaactctcat gacttaatga atatcttgca tcatcaggat
    45481 aaggaattga gagggcgttt gttggaaatg atatttacta gccaaaacta attgaaataa
    45541 ttagaaagtc atttgtttag tgtatatgaa gattctgtat ggtattcgtt atcactggtc
    45601 acattgaaaa tgtgaaataa gcacctacaa catagacttt acaacacttc atgttttata
    45661 tcatggggtg tttttctatt taagtcaaag cccatcaaaa aatctcacta ttcatcaggt
    45721 taaaggaaac ctaatcatag tgagattgtg aattatagta gagtttgtat cgcctcttca
    45781 atttgttttg ggtctgtttt tgaagaaaag cgttcaaaga cttgcccatc tcgaccgatg
    45841 agaaacttag agaaattcca ttcgattcgt tttcctagtg ggccggattt ctggtctttt
    45901 aaccagacat agagagggtc tgcttcctta ccgttgacct taatcttggc aaaacgtggg
    45961 aaggtggttt gaaaatgtag gctacagaag gcgttgattt cctctgcgct gccgggtgct
    46021 tgtcccataa actgattgca agggaaatcc aatatttcga agccctgagc ttgatagcgt
    46081 tcatagagtt cttgaagtcc ctggtactgg ggcgttaaac cacatccagt agcagtgttg
    46141 acaatcaaga gaactttgcc acgatagcta tccaagggag ttgcttggtt gttttggttc
    46201 aaaacggaaa aatcataaag tgaagtcatg agggcctctt ttctttttct acattgtaac
    46261 agtttttact tttttcgtcg agtcggatgg aagatattgt tgaagaataa gtcttcaata
    46321 tgatagaaac cgtttacaaa taactttaaa aatggtatga tttaattaaa ccggtttact
    46381 tagttgctat aaatctctaa tttgagattt agttcctatt gattttacaa tatgtttatt
    46441 ggagtgtata catgcaaaca aaaacaaaga agctcattgt gagtttgtct tcacttgttt
    46501 tatcaggatt tttattaaac cattatatga cagttggagc ggaagaaacg actacgaata
    46561 ccattcagca aagccagaag gaagttcagt atcagcaaag ggatacaaaa aatttagttg
    46621 aaaatggtga ttttggtcag acggaggacg gaagcagtcc gtggacagga agcaaagctc
    46681 aggggtggtc agcttgggta gaccagaaga atagttctgc agatgcctca actcgagtca
    46741 ttgaggctaa gggtggggct atcactatct caagccatga gaaattaagg gcagcggttc
    46801 accgtatggt tcctattgaa gctaagaaaa agtataaact gcgtttcaag attaaaacag
    46861 atcataaagt cgggattgcc aaggttcgta tcattgagga aagtggtaag gacaagcgat
    46921 tgtggaattc tgcaacgacg tcaggaacaa aggactggca gaccattgaa gcagactata
    46981 gcccgacttt agatgttgat aaaatcaagc tggagttatt ctatgaaaca ggaactggga
    47041 ctgtttcctt taaggatatt gagctggtag aggtagcaga ccagctttct gaggattctc
    47101 aaacagataa acagcttgag gaaaagattg atttaccaat tggaaaaaaa catgtttttt
    47161 ctcttgcgga ctatacttat aaggtagaaa atcctgacgt tgcttcagtc aaaaatggaa
    47221 ttttagaacc tcttaaggaa gggacaacca atgtcattgt cagtaaagat ggcaaggaag
    47281 tgaaaaagat tcctttgaag attctagcct ctgttaagga tgcatacaca gcccgtttgg
    47341 atgactggaa tggcatcatc gctgggaatc aatactatga ttctaaaaat gaacagatgg
    47401 ccaaattaaa ccaggaattg gaaggaaagg tagctgatag cctatctagt atttcaagtc
    47461 aggcggaccg cacctatttg tgggaaaaat tttcaaatta taaaatgtct gcaaatctga
    47521 ctgccactta tcggaaattg gaggagatgg ccaagcaagt gaccaatcct tcttctcgtt
    47581 attatcaaga tgaaactgtc gttcgaacag tcagggattc catggaatgg atgcataaac
    47641 atgtctacaa tagtgaaaag agcattgttg ggaactggtg ggattatgaa atcggtacac
    47701 ctcgtgccat caacaatacc ttgtctctga tgaaagaata cttctctgat gaggaaatta
    47761 aaaaatatac agatgtgatt gaaaaatttg taccagatcc cgaacatttc cgaaagacga
    47821 ctgataaccc atttaaggct ctaggtggaa acttagttga tatgggaaga gtaaaagtaa
    47881 tagctggttt actgcgtaag gatgatcaag aaatttcttc taccattcgc tcgattgagc
    47941 aagtgttcaa gttggtagac caaggtgaag gtttttatca agatggatcc tatatagacc
    48001 ataccaatgt tgcctatacg ggtgcttatg ggaatgtttt gattgatggc ctgtctcaac
    48061 tgttgccagt cattcaaaag accaagaatc caatcgataa agataaaatg caaaccatgt
    48121 actactggat tgataaatcg tttgctcctt tgctggtgaa tggagagctg atggatatga
    48181 gtcgtggacg ctcgatcagt cgtgcaaata gcgaggggca cgtggccgca gtagaagtac
    48241 taagagggat tcaccgaata gcggatatgt ctgaaggaga aaccaaacaa cgtttgcaga
    48301 gtcttgtgaa gaccattgtt caatcggata gttattatga tgtctttaag aatttgaaga
    48361 cttataagga tatcagtttg atgcaatcct tgttaagtga tgcaggagtc gcaagtgttc
    48421 caagaacaag ttacctatct gcctttaaca agatggataa aacagccatg tacaatgcag
    48481 agaaagggtt tggatttggc ttgtcactct tttccagtcg taccttgaat tacgaacaca
    48541 tgaacaagga aaataaacgt ggttggtata cgagtgatgg gatgttctat ctttacaatg
    48601 gcgatttgag tcactatagc gatggctact ggccaacagt taatccatat aagatgcctg
    48661 gtacaacaga gacggatgct aagagagcgg atagcgatac aggtaaagtt ttaccgtctg
    48721 ctttcgttgg aacgagcaaa ctagatgatg ccaatgcgac agcaaccatg gatttcacca
    48781 actggaatca aacattgact gctcataaga gctggtttat gctaaaggat aagatcgcct
    48841 ttttaggaag caatatccaa aacacttcaa cagatactgc tgcaactaca attgaccaga
    48901 gaaaactgga atcaagtaat ccatataaag tctatgtcaa tgataaagaa gcctccctta
    48961 cagaacaaga aaaggattat cctgaaaccc aaagtgtctt tttagaatca tccgattcga
    49021 aaaagaatat tggttacttt ttctttaaga agagttcaat cagtatgagt aaggctttgc
    49081 aaaagggagc ctggaaggat atcaatgaag gacagtcaga caaggaagtt gaaaatgaat
    49141 ttcttacgat tagtcaggct cataagcaaa atggagattc ttatggctat atgctcatcc
    49201 ctaacgtggg tcgtgccacc ttcaatcaaa tgataaaaga gttagaaagt agcctcatcg
    49261 aaaataacga aacccttcag tctgtttatg atgccaaaca aggagtttgg ggcattgtga
    49321 aatatgatga ttctgtctct actatttcca accaattcca agttttgaaa cgtggagtct
    49381 ataccattcg aaaagaaggg gatgaatata agattgccta ctataatcct gaaacccagg
    49441 aatcagctcc agatcaggaa gtctttaaaa agctagagca agcagctcag ccacaagtac
    49501 agaattcaaa agaaaaggaa aaatctgaag aggaaaagaa ccattcggat caaaagaatc
    49561 tccctcagac aggagaaggt cagtcaatct tggcaagtct agggttcttg ctacttgggg
    49621 cgttttattt attccgtaga ggaaagaaca actaatttgt tcatcatcta gatgaattac
    49681 atgaaactgt ggaaaataga aaaaatccga agaaggccaa atatcttcgg atttttcttt
    49741 taaaaaagga taagttgata cttatccttt ttacttcatt atgtgactat agcgttttga
    49801 aactagaata ggacatcata actgctaaaa gatttctata aattcatttg attttcctaa
    49861 tcaatttgtt cgtatcctat ttcactctac tatattagtc cgtctcgcac ctcacggagc
    49921 gagacaaaac aaccacccgc tatgcgggtg cgcgtcgaag gttataccaa aaaaactcca
    49981 aacgcgatac aataaaggtg ttcaacccac ttgtaaagcg aaaggagaaa aaatatggca
    50041 caaaaggctc atagtttatc tcacacaaag tggaggtgtt ctatcacatt gtgttcaccc
    50101 ctaagtatag acgaaaagtc atctataatc aatatagaag tagtttaggc gaaatatttc
    50161 atcgcttgtg tagttataaa ggtgttgaaa tgatcgaggg tcacttaatg ccagaccatg
    50221 tacacatgtt agtcagtatt ccactaaggc taagtgtttc gagtttcatg ggttatttaa
    50281 aaggcaaaag tgcactcatg atgtttgaca aacacgccaa tctcaagtac aagtttggga
    50341 atcggcattt ctgggcggaa ggttattatg taagtccagt agggcttaat gaagacacaa
    50401 ttaagaaata tagtcaagat taaagaaatt atcgagtgga tgatttcttc acgagtatga
    50461 aaatttgaga actagtaaag tatgatatat agtaaaatga aataagaaca ggacaaaatc
    50521 gatcaggaca gtcaaatcga tttttaacaa tgttttagaa gtagaggtgt actattccag
    50581 tttcaatcta ctatagcact agataaattg agtgtaaaag aatatgagga tccctttagg
    50641 gatagtggta agtaatacca aagtctctta aagaggcaag tgacgagtca agagcaataa
    50701 ggcttgaaca acgtgaaagc cagcgtcttt aggcgctggc tgatgatttg ggcttatagc
    50761 tctgagataa accacccgtt agacgggtag ttatgatttt atctgagtgt aacatactgt
    50821 tgggcaatct cgctgatgcg gtcaaagttg ccttgggaag cgagtttatt gagttcgcca
    50881 ccaattccaa cggcatctgc accagcagcg aaccattgag ggatgttgtt tagaccgact
    50941 cctccggtta ccattacgga aacttgtgga atcggtgcct tgactgcaga gatatatgct
    51001 ggactgagag tactacctgg gaagagtttg atgatttcac taccggcttc aagtgcagtc
    51061 gtgatctctg tgagggtaat acagcctgga atgtacggtg tgctgtagag attgcacatt
    51121 ttcgcagttt cagcatggaa agatggagaa acaacgtaat ttgctccggc tagaatggca
    51181 tctctagcag ttacggcatc aagcacagta cctgcaccga tacaaacact ctgatcgtcc
    51241 tgatacaagt ctacaagttc cttgatgatt tgtcctgcat actgattggt ataggcgatt
    51301 tcaatagctt tgataccgcc cttgatacaa gcaatcgagg cttgtagtcc ttcttccttt
    51361 gtatttcctc gaatgacagc aacaattttc tgttttttta gttcaataat tgtatctgat
    51421 ttggtcatgt aattctccta acgaatgata tcttgtgcat ttgccagtaa attttcaata
    51481 ctagttgcgg aagtggagag atggtctcct ggaagagtgc atttgagagt tgcgctcgca
    51541 actgcaaagt caatggtagt ttttagggag gaatgatgga gtagttggta aagggcacca
    51601 gatataaagg catccccgct accaattcgt tgatagactg cagtttttag ttggacagac
    51661 tcttcaaatc gttcttccag agcataggct tgatagacat ttttgtcttg ctcatcacta
    51721 gagcggaggg tatggaaaat ggccttgaaa ccataggctt cttttaaaag tcgcatgcga
    51781 ttttccacct cttctaggct agcactgtct cttggaaaca tctctagatt ttggtcatca
    51841 atcatgagag gatcaatacc gaagcaatag tcagtaaaac gtgcaaactt agaaaattca
    51901 tacttggctt ctaggactga aatcatcttt gttctcagat tgagatccat tgaaacgaca
    51961 attcctcggc gcttggcttc ttccaagagt aggagaagga tcgcacggac ctcttgaccg
    52021 atagctacgg tgattccact aaaatgaaaa tggctaatcc cctgaaagag agaatccata
    52081 tctagcatgt ttggccgaat ctggctgata ctcgtatgct tacgatcgta gaaaacttca
    52141 ctttgacgac aaccaaagcc gttctccaaa tagtagaggc cgattcgatc gccaagccga
    52201 cagattgaac tggtatcgat ttggtgctgt ttcaagaatg tgagaaaacg atctccaatc
    52261 tcgttggcag ggagtgcggt aaagactttc gttgagatac ccagggcttg caaattacaa
    52321 gcgatgttaa tttctgatcc gccaaaataa gtcgaactgg caacatgatc tccgatactg
    52381 gtggcatcta atggtgagat tcgaattaat ggttcgccaa acagtaatat tttcgtcatc
    52441 cattagttcc tttctggttt agaatagctt tacttggcta atacttcttt caaataagca
    52501 gcgacttcat catcttggca gttttcaaag aagtattctt ggaagtattt gccagatatg
    52561 gtgtctttga ggaagtcttg gtcgattgtt ttaaggatgg tcatcaaatc attgtgggtg
    52621 atttgtttca cctcgtttaa gatacgagcg ttgcgttgtt cagggattac acgttctctt
    52681 gggtagccac cgcccatttc ttcagcaaat aagcgttcaa acatcaattt gagggtcagt
    52741 tctgcccccc agccaaatcc tttggcataa gggatagaca aggcgttacc accattgatt
    52801 tgagaataaa ggtaagcgtc agttgggtcc actgctagac cacagacaac accagggaag
    52861 ctgtttaaag caagcatagc ccctacaccc gtaccacagc cggtaacaac aaagtcaact
    52921 gcctttgtat ttaaaaggat ggcagccatt agtccgttct gcacataagt taattgactt
    52981 tctccttctt ctccacgcat accatagtta aataattggt agtctttttt atctgtcgct
    53041 tcttttagac tatcgtaaat aatgtgattc ttgctagctt gactattttc attgattaat
    53101 gcgattttca taagatcttc tttctatttt tactcaggtt gttttccgat gtaggctaag
    53161 ataccgccat ctacatatag gatgtggcca ttgacaaaat tgctggcatc actagcgaga
    53221 aagacagcag ggcccatcaa atcttcagga tttccccaac gtgcagcagg tgtttttgca
    53281 atgatgaact ggtcaaatgg gtggcgagaa ccatcttctt gcaactcacg aagaggtgct
    53341 gtttgaggag tggcaatata acccggtcca attccgttac attggatatt ggctccaccg
    53401 tattcagacg caatgttgcg ggtcaacatt ttcaagcccc ctttagcagc agcataagcg
    53461 ctaactgttt cacgtcccag ttcgctcatc atcgaacaaa tattgataat ctttccatgc
    53521 cctttcttta tcatagaagg aataactgcc tttgaaacga taaatggtgc gtttaagtca
    53581 atatcgatga ccttacggaa atcagcggcg ctcatttcgc acattggaac tcggcggata
    53641 ataccagcgt tattaacgag gatgtcaatg acaccaacct cttgttcgat ttgcttgacc
    53701 atggcttgga taccgtcctc gtctgtcacg tcacagacat atccatgggc ttcgatgcca
    53761 acttcacgat aagcttcaat ccctttattg accagatctt gattgatatc gttaaagaca
    53821 atagtagcgc cggcttcagc gtaggatttg gcaatagcaa atccaattcc ataagaagcg
    53881 ccggtgatga gagcaatttt tccttttaaa gaaaactgct caattgagaa tgatgtattt
    53941 gtcatttgat gcttcctttc aaatttgtta agacttctc
//
LOCUS       DAVLAQ010000008        51996 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000008 DAVLAQ010000000
VERSION     DAVLAQ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.008"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(98..1459)
                     /gene="dnaA"
                     /locus_tag="VXB71_000444"
     CDS             complement(98..1459)
                     /gene="dnaA"
                     /locus_tag="VXB71_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0450614.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1672..2430)
                     /locus_tag="VXB71_000445"
     CDS             complement(1672..2430)
                     /locus_tag="VXB71_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0450615.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2488..3669)
                     /locus_tag="VXB71_000446"
     CDS             complement(2488..3669)
                     /locus_tag="VXB71_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0450616.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3852..4331
                     /gene="rlmH"
                     /locus_tag="VXB71_000447"
     CDS             3852..4331
                     /gene="rlmH"
                     /locus_tag="VXB71_000447"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0450617.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4375..4448
                     /locus_tag="VXB71_000448"
     tRNA            4375..4448
                     /locus_tag="VXB71_000448"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4409..4411,aa:Arg,seq:tct)
     gene            4613..4738
                     /gene="comC"
                     /locus_tag="VXB71_000449"
     CDS             4613..4738
                     /gene="comC"
                     /locus_tag="VXB71_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0450618.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            4759..6084
                     /locus_tag="VXB71_000450"
     CDS             4759..6084
                     /locus_tag="VXB71_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0450619.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYIFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     FKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6081..6833
                     /locus_tag="VXB71_000451"
     CDS             6081..6833
                     /locus_tag="VXB71_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450620.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6885..6956
                     /locus_tag="VXB71_000452"
     tRNA            6885..6956
                     /locus_tag="VXB71_000452"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6918..6920,aa:Glu,seq:ttc)
     gene            6962..7035
                     /locus_tag="VXB71_000453"
     tRNA            6962..7035
                     /locus_tag="VXB71_000453"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6996..6998,aa:Asn,seq:gtt)
     gene            complement(7076..7618)
                     /locus_tag="VXB71_000454"
     CDS             complement(7076..7618)
                     /locus_tag="VXB71_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0450621.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDVIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7797..8564
                     /locus_tag="VXB71_000455"
     CDS             7797..8564
                     /locus_tag="VXB71_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0450622.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDSYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            8649..8987
                     /locus_tag="VXB71_000456"
     CDS             8649..8987
                     /locus_tag="VXB71_000456"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450623.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            9015..9329
                     /locus_tag="VXB71_000457"
     CDS             9015..9329
                     /locus_tag="VXB71_000457"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0450624.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(9430..11982)
                     /locus_tag="VXB71_000458"
     CDS             complement(9430..11982)
                     /locus_tag="VXB71_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0450625.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12044..13666)
                     /locus_tag="VXB71_000459"
     CDS             complement(12044..13666)
                     /locus_tag="VXB71_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0450626.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13872..14897
                     /gene="trpS"
                     /locus_tag="VXB71_000460"
     CDS             13872..14897
                     /gene="trpS"
                     /locus_tag="VXB71_000460"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0450627.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15049..16527
                     /gene="guaB"
                     /locus_tag="VXB71_000461"
     CDS             15049..16527
                     /gene="guaB"
                     /locus_tag="VXB71_000461"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0450628.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16578..17675)
                     /gene="recF"
                     /locus_tag="VXB71_000462"
     CDS             complement(16578..17675)
                     /gene="recF"
                     /locus_tag="VXB71_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0450629.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(17678..18046)
                     /gene="yaaA"
                     /locus_tag="VXB71_000463"
     CDS             complement(17678..18046)
                     /gene="yaaA"
                     /locus_tag="VXB71_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0450630.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18205..19455
                     /locus_tag="VXB71_000464"
     CDS             18205..19455
                     /locus_tag="VXB71_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0450631.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            19452..20735
                     /locus_tag="VXB71_000465"
     CDS             19452..20735
                     /locus_tag="VXB71_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0450632.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20777..21598
                     /locus_tag="VXB71_000466"
     CDS             20777..21598
                     /locus_tag="VXB71_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0450633.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFIFFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21609..22154
                     /gene="pgsA"
                     /locus_tag="VXB71_000467"
     CDS             21609..22154
                     /gene="pgsA"
                     /locus_tag="VXB71_000467"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0450634.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22151..22978
                     /locus_tag="VXB71_000468"
     CDS             22151..22978
                     /locus_tag="VXB71_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0450635.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22963..23802
                     /locus_tag="VXB71_000469"
     CDS             22963..23802
                     /locus_tag="VXB71_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0450636.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23795..24589
                     /locus_tag="VXB71_000470"
     CDS             23795..24589
                     /locus_tag="VXB71_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0450637.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24648..25466
                     /gene="mreC"
                     /locus_tag="VXB71_000471"
     CDS             24648..25466
                     /gene="mreC"
                     /locus_tag="VXB71_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0450638.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25466..25960
                     /gene="mreD"
                     /locus_tag="VXB71_000472"
     CDS             25466..25960
                     /gene="mreD"
                     /locus_tag="VXB71_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0450639.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26054..27232
                     /locus_tag="VXB71_000473"
     CDS             26054..27232
                     /locus_tag="VXB71_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0450640.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27456..28235
                     /gene="rpsB"
                     /locus_tag="VXB71_000474"
     CDS             27456..28235
                     /gene="rpsB"
                     /locus_tag="VXB71_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0450641.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28314..29354
                     /locus_tag="VXB71_000475"
     CDS             28314..29354
                     /locus_tag="VXB71_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0450642.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            29600..29923
                     /gene="tnpB"
                     /locus_tag="VXB71_000476"
                     /pseudo
     CDS             29600..29923
                     /gene="tnpB"
                     /locus_tag="VXB71_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(30078..30365)
                     /locus_tag="VXB71_000477"
                     /pseudo
     CDS             complement(30078..30365)
                     /locus_tag="VXB71_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30356..30754
                     /locus_tag="VXB71_000478"
     CDS             30356..30754
                     /locus_tag="VXB71_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0450643.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(30951..31871)
                     /gene="cysK"
                     /locus_tag="VXB71_000479"
     CDS             complement(30951..31871)
                     /gene="cysK"
                     /locus_tag="VXB71_000479"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0450644.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYNGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(32156..32791)
                     /locus_tag="VXB71_000480"
     CDS             complement(32156..32791)
                     /locus_tag="VXB71_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0450645.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDNGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            32847..34145
                     /locus_tag="VXB71_000481"
     CDS             32847..34145
                     /locus_tag="VXB71_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0450646.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSNLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            34142..34804
                     /locus_tag="VXB71_000482"
     CDS             34142..34804
                     /locus_tag="VXB71_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0450647.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREEGASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            34884..35432
                     /gene="raiA"
                     /locus_tag="VXB71_000483"
     CDS             34884..35432
                     /gene="raiA"
                     /locus_tag="VXB71_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0450648.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            35568..37541
                     /locus_tag="VXB71_000484"
     CDS             35568..37541
                     /locus_tag="VXB71_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0450649.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            37538..37990
                     /gene="rplI"
                     /locus_tag="VXB71_000485"
     CDS             37538..37990
                     /gene="rplI"
                     /locus_tag="VXB71_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0450650.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            38034..39386
                     /gene="dnaB"
                     /locus_tag="VXB71_000486"
     CDS             38034..39386
                     /gene="dnaB"
                     /locus_tag="VXB71_000486"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0450651.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            39388..39654
                     /locus_tag="VXB71_000487"
     CDS             39388..39654
                     /locus_tag="VXB71_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450652.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            39743..40861
                     /gene="cbpD"
                     /locus_tag="VXB71_000488"
     CDS             39743..40861
                     /gene="cbpD"
                     /locus_tag="VXB71_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0450653.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGLWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      40944..41046
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41117..41407
                     /locus_tag="VXB71_000489"
     CDS             41117..41407
                     /locus_tag="VXB71_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0450654.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            41370..42128
                     /locus_tag="VXB71_000490"
     CDS             41370..42128
                     /locus_tag="VXB71_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450655.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            42166..43173
                     /locus_tag="VXB71_000491"
     CDS             42166..43173
                     /locus_tag="VXB71_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0450656.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            43173..43901
                     /locus_tag="VXB71_000492"
     CDS             43173..43901
                     /locus_tag="VXB71_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450657.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            44020..44478
                     /locus_tag="VXB71_000493"
     CDS             44020..44478
                     /locus_tag="VXB71_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0450658.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            44480..46912
                     /locus_tag="VXB71_000494"
     CDS             44480..46912
                     /locus_tag="VXB71_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0450659.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            47233..47886
                     /gene="rr06"
                     /locus_tag="VXB71_000495"
     CDS             47233..47886
                     /gene="rr06"
                     /locus_tag="VXB71_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0450660.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            47883..49223
                     /gene="hk06"
                     /locus_tag="VXB71_000496"
     CDS             47883..49223
                     /gene="hk06"
                     /locus_tag="VXB71_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0450661.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSRLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            49306..49833
                     /locus_tag="VXB71_000497"
     CDS             49306..49833
                     /locus_tag="VXB71_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0450662.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            49912..51831
                     /gene="pspC"
                     /locus_tag="VXB71_000498"
     CDS             49912..51831
                     /gene="pspC"
                     /locus_tag="VXB71_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0450663.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSEN
                     NPTVTSSGQDISKKYADEVKSHLEKILSEIQTNLDRSKHIKTVNLINKLQDIKRTYLY
                     ELNVLEDKSKAELPSKIKAELDAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKAKAQ
                     KEEDYRNYPTITYKTLELEIAESDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     QAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDHRNYPTITYKTLEL
                     EIAESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEED
                     YARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQYNG
                     SWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGAMVTGWLQY
                     NGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNT
                     TVDSYRVNANGEWVN"
BASE COUNT        16475 a         8455 c        10935 g        16131 t
ORIGIN      
        1 tctgtggaaa acagccttta aacaagtcat atcaagtttt ttagcttgtt taaaaaatgt
       61 ggataaaaaa gataaaaaac taaaagttat ccacaaatta tttgattttc tttttgattg
      121 attcaatttc taaacgtaaa ttatcgtctt gatcaatcaa agattttatt ttggcatggg
      181 catgaatgac tgtggtatga tcttttcccc caaattcctt cccaattttt ggaagactat
      241 tatctgttag ttctctagat aaatacatgg ctacttgacg ggccaaaaca atattttgaa
      301 ggcgtctact tcccttcatt tctttgatac taacaccata aaagttacca acttcagttt
      361 ggattttatc aattgggatg acgagcattt ggctaacatc ttgtttgcgg gctctaatgg
      421 cttctgcagc aatatcaata gtgatatcct tgattttttt tactctggca attaaagtga
      481 tgtcgttgat ggctccctca agatctcgaa catttgaatc aaattgccca gctaggtatt
      541 ctagagtatc actttggaaa ttgtagccta aatgttccgt cttactttgt aaaatggcaa
      601 tacgtgtttc aaagtcaggg ggtgtgatag tttgtgtcaa tccccaacta aaacgcgtga
      661 caagcctctc ctcgagccct tctagatgtt ttggactacg atcactcgtt aggacaatct
      721 gtttttgctt gtcatgaagg gcgttaaagg tattgaaaaa ttcttcctga gttgcgactt
      781 tttttccgct gagtgactgt atatcatcga ttaacaaaag atcaagacta cgataggtct
      841 ttttaaactt ttccatttcc ccaagtctta ggtgatcaag aaagtcatta ataaagcttt
      901 cggcagggat atatttaaca cgcgcattag gaatattttt tagaatttca tttccaatag
      961 cgtttaataa gtgagtctta ccaaggcctg gtcctccata gataaaaaga gggttatagg
     1021 tcagagccaa atcttcagag acagctaaag cggctgatac agcccaaaca tttccatccc
     1081 cttgaataaa gttatcaaag gtatactttt cttttaatcc cgtatctgaa taaggaatag
     1141 atactaactt tggactatag tcataaagag ttaaatttgt agcttcttca acttgtgagc
     1201 tagtcgtatc ttgaggtttg gtgaaaatat agtggggagt tatttcagcg tcataaattt
     1261 caaaaccagc tactacaata atatctttta gttgtttttc ccagaccatt tccatttcag
     1321 agcgaggtag aaatatagtg gcaacatttt cctctacctt gatgagttca gcttgaatag
     1381 catagaaatc atacatggat cgagtcagtc tttcttgtgc aaattctaat atacgattcc
     1441 aaaattgttt ttctttcaat cctttctcct cctttactat ttaaaagttt aatactagag
     1501 atattttacc atagatagca agaattttcc acaagctgtg aaaaataatc cacaatgtta
     1561 ccaaacttta tccacaggtt ggggataaaa gaagaaatta ttgatttatt aagcttttta
     1621 tcgaaaaaca tagtggataa ccttgtgaga taaaaaaata aaagaacagc cttatttcag
     1681 gctgttgata attctactat attcttcttg atttgaaaaa gaaataatga tttttccact
     1741 gtctttttta gatagtttaa tttctacatc taatccgagt agttttctta actgtttttc
     1801 ttcattttgt atgaaatgat tagttttttg ctgtttcttt tgttttttct ctgtcagaag
     1861 agtttctaac ttccttacag aaatatcttc ttctataatc cgttgaaaga aatagtcttg
     1921 ttgttcctta tttaacccaa ctagggaacg cgcatgggct tgtgatagtt tgccattttc
     1981 tacttctgag agaatctgtt ctggcaagga aagtaaacga atggagttgc tgatatatgg
     2041 acgagacttg cccatcttat ctgcaatttc agcatgggtg aatcctttct ctacgagaga
     2101 ttcataggcg cgtgcttctt ctattgggtt taaattttct ctctgtaaat tttcaataat
     2161 ggactggacc atcatctctt ggtctgaaat ctgtttaaca acagctggga tagaccgtag
     2221 accagctaaa agtgaagccc gatagcgtct ctctcctgca aggatttcat aaccaataac
     2281 aggagattga cgaacaataa tcggttgaat gaccccattt tctttgatag actgtgctag
     2341 ttcatctagc ttttctctat caaattcttt tcggggttga tagggatttt tttgtatatc
     2401 tgtgatagaa atcatttcaa atttttccat gattctacac taacacatct tttctcttat
     2461 gtaaagcttt ctttacatag atgtcaatta agattctaaa tcacctgaac tcttgttaag
     2521 tttgatagag gtagtttctt ctttcccgtt acgatagtag gttatcttaa tggtgtctcc
     2581 gatagaatgg ttgtaaagag cactttgtaa gtctgttgat gaagcaatct ctttgtcatc
     2641 tacttttgta attacatcgt atttttcaag gtgaccattg gcaggcatat tactttgtac
     2701 cgaacgaaca actacaccag atgtaacatt acttggaata ttgagtcttc tgatgtcgct
     2761 tgtactcaca ttagataaat taaccatctg gattcccaaa gctggacgcg tcacttttcc
     2821 gtttttttct aactgttcaa taatattgat agcatcattt gcaggaattg cgaaaccaag
     2881 accttctaca gatgttcctc catttgtagc aattttactt gaggtaattc cgataacctg
     2941 cccttgaata ttgatcagtg ggccgccaga gttacctggg ttaatagcag tatcagtttg
     3001 gatggctttt gtagaaatag cttgtccatc ttccgatttt aaggatacat ttctattgag
     3061 actggatacg ataccttgag tgacagtatt tgcatattca gaacctaacg ggctaccgat
     3121 ggcaatagca gtttctccta cagttaactt actagaatca ccaaactcag ctactgttgt
     3181 cactttttct gaagagattt ttacgacagc aatatcagag aaagtgtcag ctccgacaat
     3241 ttctccaggt actttagtcc catctgacaa tcgaatatct actttgctgg cgccatttat
     3301 aacgtgattg ttggtgacga tgtaagcttc tttatcattc tttttataaa taactccaga
     3361 tccttcacta gagattcgct gagaatctgt gtcagtatca tcattgccaa atacgctatt
     3421 ttgtctgttt gccgaataag taataacaga aacaacagca tcttttactt tgttaacagc
     3481 ctgtgttgtt gaattttcgt tcttataggc agtttgtgta atagtactat tattgttaga
     3541 gttgtttaca ctactttttt gagttagttg agttattgaa aaactaccca aggctccact
     3601 aaaaaagcta atgacgataa cgactaataa ttgaaaccat tttttgtaaa atgtttttag
     3661 atgtttcata tttgcctcca tatgtttgaa ttactgaaag tataaactga ctagcttaat
     3721 tataacttaa acacaaaagt tttacacaaa ctgtggataa ctcttttgaa actgtgattt
     3781 tcttaattga aatctatttt ttattttgtg aataagatgt gaaaaaatag agaatatgtt
     3841 agaatagagt catgaaaatt aaagttgtaa cagttgggaa actgaaagaa aagtatttaa
     3901 aagatggtat cgcagagtat tcaaaacgaa tttctagatt tgctaagttt gaaatgattg
     3961 agttatcaga tgaaaaaaca ccagataagg ccagtgaatc agaaaatcaa aagattttag
     4021 aaatagaagg tcagagaatt ttatcaaaaa ttgctgaccg tgatttcgtt attgtgttag
     4081 ccattgaagg gaaaactttc ttctcagaag aatttagtaa gcagttagaa gaaacttcta
     4141 taaaaggatt ttctactctt acttttatta ttgggggaag tttaggattg tcatcatctg
     4201 taaaaaatag agccaatctt tctgtcagtt ttggtcgcct aaccttgcct catcagttaa
     4261 tgagactagt tcttgttgaa caaatctatc gcgcttttac gattcagcag ggattcccct
     4321 accataaata gaaaattgac ttttaattga atttttggta gaataattgt gttaggtctc
     4381 atagctcagc tggatagagc attcgccttc taagcgaacg gtcgcaggtt cgaatcctgc
     4441 tgggatcaat ataatagcaa agctgggaat tttcccggct tttttcttaa aaaagtacac
     4501 tttgggagaa aaaaatgaca gttgagagaa ttttatctaa agtgaaattc cattttgtat
     4561 aatggttttt gtaagttagc ttacaagaaa aaacatttta ggagatttta ttatgaaaaa
     4621 cacagttaaa ttggaacagt ttgtagcttt gaaggaaaaa gacttacaaa atattaaagg
     4681 tggggagatg aggatttcaa gaatcatcct tgattttctt ttcctacgaa aaaagtaatg
     4741 aaataaggag aaagagtaat ggatttactt ggatttggga cagttattgt tcatttttta
     4801 attattagtc acagttaccg tttaatttgt aaaggtcgaa taaatagaaa agaattatac
     4861 atttttggtg cttatacatt actaactgaa atagtacttg aattttcctt ttatcttcta
     4921 tatttagata aaatagggat tgaaagattt ttatttcctt tgggcttata ttcctatttt
     4981 cgatggatga aacagtatga gagggataga ggactattcc taagtttact actatctctt
     5041 ttatatgaga gcactcataa ctttctgtcc gtaactttct cctctataac aggagataat
     5101 tttgttttac aatatcattt cccattcttt ttcgttgtga cggtgttaac ctattttgtt
     5161 acattaaaaa tcatttatta tttccatttg gaactagcct attttgacaa ggactacctt
     5221 tatcctttct tgaaaaaagt attttttgct ttactattgc tacatattgt atctttcgtt
     5281 tcagatatgg taagtacgat taaacatttg aatagttttg gaagtatttt gtcatctatt
     5341 gtctttatct ctctcctttt gaccttcttt gcaatgaatt ctcataaagt tcaaatggag
     5401 aaagagattg cttttaagca gaagaaattt gaacagaaac atttacagaa ttacacagat
     5461 gaaattgttg gtctgtataa tgaaatccgt ggttttcgac atgattatgc tggaatgctt
     5521 gtcagcatgc agatggcaat tgacagtggt aatttacagg aaattgacag aatttacaat
     5581 gaagttttag tcaaagcaaa tcataaattg cgttcagata agtacactta ctttgatttg
     5641 aacaacatag aagactcagc tttacgaagt ttggttgctc agtcaattgt ctatgctcga
     5701 aataatggtg tagagtttac actggaagta aaagatacga ttaccaagct tccaattgaa
     5761 ctattggatt tggttcgtat catgagcgtt ttattgaata atgctgtcga aggatcggct
     5821 gatagctata aaaagcagat ggaagtagca gttattaaga tggaaactga aacagttatg
     5881 gtgattcaga attcatgtaa aatgacgatg actccttcag gagatctatt tgccttagga
     5941 ttctccacta agggaagaaa tcgcggagtc ggattaaata atgtgaaaga actactagat
     6001 aagtacaaca atattatttt agaaacagag atggaaggca gtacatttag acaaatcatt
     6061 agatttaaga gggaatttga atgaaagttt taattttaga agatgttatt gaacatcaag
     6121 tgagactaga gagaatattg gatgaaattt cgaaagaatc gaatattcca atatcataca
     6181 agacaacggg aaaagtccgt gaatttgaag aatacattga aaatgatgaa gtaaatcagc
     6241 tttatttcct agatatcgat attcatggaa ttgagaaaaa gggatttgaa gtggctcagc
     6301 tcattcgtca ttacaatcct tacgctatta ttgtctttat cactagtcga tcagagtttg
     6361 cgactctaac ctataaatac caggtatcag ccctagattt tgttgataag gatatcaatg
     6421 atgagatgtt taagaagaga attgagcaaa atatcttcta cacgaagagt atgttacttg
     6481 aaaatgaaga tgttgtagat tatttcgact acaattacaa gggaaatgat ttaaaaattc
     6541 cttaccatga tattttgtat attgaaacaa caggggtatc tcataaattg cgcattattg
     6601 gtaagaattt tgcaaaagag ttttatggta ccatgacaga tattcaggaa aaggacaaac
     6661 atactcagcg attttattct cctcacaagt catttttggt aaatataggc aatatcagag
     6721 aaattgatcg aaaaaactta gaaattgttt tctatgaaga ccatcgttgt cctatttcaa
     6781 gattaaaaat tagaaaatta aaagatattt tagagaaaaa atctcaaaag tgattgacaa
     6841 ttagcaagaa attgatataa tggttatatc tgctacagat agaaggtccg ttggtcaagg
     6901 ggttaagaca ccgccttttc acggcggtaa cacgggttcg aatcccgtac ggactatttt
     6961 atccgccata gctcagttgg tagtagcgca tgactgttaa tcatgatgtc gtaggttcga
     7021 gtcctactgg cggagtatag ataaaaggga acacagctgt gttcctcttt ttgtatcaat
     7081 ttgtatcacc aagcattttc ataaggaagt ctgttatttc ttgagaactt tctttttttc
     7141 catgtgcaat ccaagtttgg cagacaccaa aaagtgcatg agttagatag atgctactat
     7201 attctaattc agtggtattt agattcagtt gcataaatcg cttttgtaaa tctatactga
     7261 gcatgatatg aagtttattt cgtaagaaat tttggatttc tttagtccca ttttcagaaa
     7321 gaagggcagc cagaagtggt tctgactcta gatattcaaa gacttctaaa atagcgtctc
     7381 ttttgtgatg agcatgtttt tgaaaaatat attcaaatgt atggaatagc ttgctttgat
     7441 agtgctcaat cacatcatac ttatccttat agtgagtata gaagctggaa cgactaattc
     7501 cggctttttc tactaatttg acagtagaaa ttttatcaaa tggctgttcc atcagtaatt
     7561 gtaccatagc attttcaata gttcgctttg tttttaagcg tttgttactt tcttgcatat
     7621 ttcctccttg taaacaaatt agactatatg tctaaaaata gattttttat cttgtaattt
     7681 agatttttta atgtataatc tattatatta aaattttaga caatatgttt aaaaaaggag
     7741 aaactaagtt taaagaatgg aaagcaattt aaaaaaaacc aacctttatt attgtcatga
     7801 tcgggatttc tcttattcca gatctgtaca atatcatatt tttgtcatca atgtgggatt
     7861 catatgggca attgtctgac ttacctgtgg cagttgtaaa taatgataaa gaggcttcct
     7921 ataatggtaa tactatggca ataggaaaag acatggtgtc caatttaaaa gaaaataaaa
     7981 ccttggattt tcattttgta gatgaagagg aaggaaagaa gggattggaa gatggcgatt
     8041 actatatggt agtgacttta ccaagtgatt tatctgaaaa aacaactaca ttatccaata
     8101 ttcaatcgac agcagcttat caatcattga caagtgagca acaaactgag ataagtgatt
     8161 ctgtatctca aaattcaact gatagtattc aatcggctca gtcaattgta gctttagtac
     8221 aagatttaca gggaagttta gaaaacttac aaaatcaatc ttctaatctt tcgactttaa
     8281 aaaatcaatc taatcaagta tcacctatta cttctacttc tttgatagga ttgtcaagtg
     8341 gattaacaga gatacaagga gatgttacta gcaaattagt tcctgccagt cagtcgattg
     8401 catcaggtgt aaacgcatat actacaggtg ttgataaagt ttctcagggc gcaagtcaac
     8461 taagtgaaaa aaatgccacc ttgacaggta gtttggataa actagtttca ggctcaaaca
     8521 ccttgacaca aaaatcttct agattgacag caggagttgg ttaattacaa tcaggatctg
     8581 ggcaattagc agacaaatcc agtcagttac tttcaggtgc ttctccatta gagaatagag
     8641 ctaataaatt ggcagatgga tctgggaaac tagcagaagg tggaacaaag ttaacttctg
     8701 gattggaaga tttacagaca ggacttgctt ctttaggaca aggactaggt aatgctagtg
     8761 atcaactcaa atcagtatca acagaatcta aaaatgcaga gattttgtca aatccactca
     8821 atctttcaaa aacagacaat gatcaagttc ctgtaaatgg aatcgcaata gctccttata
     8881 tgatatcagt tgctcttttt gttgcagcaa tatcaacaaa tatgatattt gcgaaattgc
     8941 cttcaggacg tcatccagag agccgttggg cttggttgaa atcttgagct gaaataaatg
     9001 gtattatagc tgttttggca ggaattttgg tatatggagg agttcagctt attggtttaa
     9061 ctgctaatca tgagatgaga atatttattc tcatcatcct aacaagttta gtattcatgt
     9121 ctatggtgac cactttagca acgtggaata gccgtatagg agcttttttc tcacttattt
     9181 tgcttttact acagttagca tcaagtgcag gtacttatcc acttgctttg acaaatgatt
     9241 tctttagatc tattaatccc tggttaccaa tgagctattc agtttcggga ttacgacaaa
     9301 caatctctat caacaagtca ttttcctagc tgtcatacta gttctattta ctagtttagg
     9361 tatgctagcc tatcaacata agaaaatgga agaagattaa aaaaatcgac cgattaactg
     9421 gtcgattttt tatgccttag atgactttcg tctgtgatta tagattccaa atagtaagag
     9481 agaagtaaag gaacagattg ctccagtaat aaaaccattg ggaatgaagg aaagtgtaat
     9541 agttcctttc cccttgggaa tgtcaacttt cataaatcca gtttgagctt gtttaatttc
     9601 tattttctta ccatcttggt aggcagacca acctttgtca taaggaatgg tgaagaaaat
     9661 agatgtatct tgttggacat catatgtagc aaaaaccttg tttttagaag ttgatactgt
     9721 gacaggttgt tctttaattt tttgaattgc ctcggtgaaa gttttggtat ctaaacgata
     9781 gaaggtagga gattcaaatg atacttgtga atttccaggg aaactaacat tgatattgaa
     9841 agtttttttc tctttagtat atcctagatt aaagaaggag aagacattat cagttgtaaa
     9901 agtctttttt tcaccattta caaggatgtc aaccttcttt tgtttatcgt tagaaaagtg
     9961 aaggtttatg aaagagagat aaacttggct gttttctgga acttcaattt gatactggat
    10021 tgctgcatct tcatttgaag aacttgtgac actaatcaaa tcattagtat tttctatttt
    10081 ttctgttttt tcataaggta ttggagaaaa ataatcaaaa ttgacgttag caagttgatt
    10141 taaaaatgag gcctgattat ccaaggtatg ttcattgaac ttgacatcat tgtaaacaga
    10201 ttgactagca actgcaatcg gaagagagta ttgattttca tatagggtaa gattatcttt
    10261 ttgatagata tctttaaagc catacttatc aataggactg tctgagatat tgtactggat
    10321 accaaataaa ctatcagcca aaatactatt atttgcatat cggagattga gattagtccc
    10381 agaggattta aaaccaagtt tatctaaagt agagcttgat gaacgatttc gaacagatga
    10441 aaattgagag attccattgt agttgaattt catactgtca tttcctgtct gagtttgtag
    10501 tttttcagta cgagtaaatt gatttccaat atatgttgag aaagattcca tagctgggat
    10561 atctcgacta taagcacttc gagaagcaaa tccccattcc ttagcaattc cgtccatttg
    10621 agatgaagca tttaaactca tttcaaccag tataaataaa gagattagaa tggcaaatag
    10681 attcacagat ataaactttt tgataactgc aaggagtaaa agagaataga caaccaaaaa
    10741 ttcaagagta agcagaatat tcaaatctgt taaaaaagaa taatgcgatt ttagatagat
    10801 ggtagctaaa aatcctgtta ctacaagaaa aagcgaaact aaaaaattcc agactttaag
    10861 ttctttcaga cgctttaaga cttctgctgc tgtgtaaatt aacaaggtag agaaaatcca
    10921 agcatagcga tgtaaaaaca tgtttggagt atgcatgcct tgccaaaata agtcaagagc
    10981 ttctatgtaa aagcttgcaa ttagaaatgc aaagaatatt acatatatga gtttcacgtg
    11041 aaacttaata gatttcagcg taaaaaataa aatggtcaaa ataaagggaa atagtccaac
    11101 aaaaatcatt gggatggccc catactttgt tgtgtcaaag gaaccaatga attgcttagc
    11161 aaagagatca agataccagc tactttcagt ttgaaacttt gtaacttcag tcaatttttc
    11221 cccatgtgtc tgtaaatcaa atagagtggg aagagtcata atcaaactag ccataccagc
    11281 taaaaaggag ataactatga aatcaagaac agatgatttt cgagtcttaa agtcccacga
    11341 aatttgacag agataccaga aaataagaaa caatactgtc atatatccaa aataataatt
    11401 ttgaataaat aagattgaca gacttgtaaa gtacaatagg agtttctttt cagttatcag
    11461 tagatgtaaa ccagttataa ttaaaggaat caagataaaa acatctagcc aggtttttat
    11521 ctctaattga ctgacagtga aactcatcag agcataggaa gtagataagg ctagttttaa
    11581 agtctgaggg atagattgaa acaatttatt caaactaaaa aaggttgaca gaccaatcaa
    11641 tccaaatttt aagagagtgg tcagatagac agcatctggc atattcgtta gatcaaaaaa
    11701 gtaaactaga ggcgcgagaa aactacccaa gtaataacta gatagggcat agaagtttag
    11761 ccctagacca cttgtaaagg tgtaaaacag actactattt ccatgtagga tatttcgtaa
    11821 ggctacatca aaaataacgt attgatgaaa gccatctcct aatagaggag agttgtcgct
    11881 attccagtag ataccttgag atagatatac tccagacata atcactacag gaatgatgaa
    11941 agaaataaaa taggttcgat atgtttttaa aaatgatttc atgttacctc gtagaatgat
    12001 agaaaactca gttggttaac ccaactgagt tttgaagttt tatttagtct ttccaaagtt
    12061 ctttaacttt tgcttgtact tctgcatttt ctaggaattc atcgtaggtt tcatcgatac
    12121 ggtcaatgac gccattttta gataagacaa tgatatggtt agccaaagtt tgaataaact
    12181 cgtggtcatg gctggcaaag atgattgatt ctttaaagtt tttcaatcca tcattcaagc
    12241 ttgagataga ttccaagtcc aagtgatttg ttggatcatc aagtacaagg acatttgatt
    12301 ttaagagcat gagttttgaa agcatgacac gaactttttc tccccctgac aagacattta
    12361 caggtttgtt aacttcatct ccagagaaga gcatacggcc gaggaaacca cgtaggaaag
    12421 tattgtcatc atcttcttta cttgcgaatt gacgcaacca gtcaagaatt gattctcctc
    12481 ctgcaaaatc agctgagtta tcttttggta ggtaagattg actagttgta actccccact
    12541 tgacagttcc ttcatagtca atatctccca tgattgcacg aattaatgca gtcgtttgaa
    12601 tatcattttg tccaataagt gctgtcttat catctggacg caagatgaaa ctaatattat
    12661 ccaagatagt ttcaccatca atctttacag ttagattttc tactgtcaag agatcattac
    12721 caatctcacg ttccgcttta aagttgataa atggatattt acgactagat ggtacaatct
    12781 cttctagctc aatcttatca agcattttct tacgtgatgt tgcctgcctt gacttagaag
    12841 cattggcaga gaaacgagca acgaattctt gcaattgttt aattttttct tctgctttag
    12901 cattacggtc tgctagcaat ttagcagcaa gctcagaaga ttccttccag aagtcgtagt
    12961 ttccgacata gagtttgatt tttccaaagt caaggtcggc catgtgagta caaactttgt
    13021 ttaagaagtg acggtcgtgg gatactacga taactgtgtt atcaaagtca attaagaagt
    13081 cttctaacca agtaatcgat tggatatcca aaccgttagt aggctcgtcc aagagaagaa
    13141 catctggttt accaaaaagt gctttggcga ggagaacctt tactttttca ccgttggcca
    13201 attcgctcat gttttggtag tgtaattctt ctggaatgtt taggttttga agtagttgag
    13261 aggcttcact ctctgcttcc caacctccaa gttcggcaaa ctctccttcg agttcggcag
    13321 cacgaacccc gtcctcgtct gagaaatctt ccttcatgta gatagcatct ttctctttca
    13381 tgatgctata aagtttttca tttcccatga taacgacatc aatggcacgt tcatcttcgt
    13441 agtcaaagtg attttgacga agaacagaga gacgttcatc tggaccaaga gagatgtgac
    13501 cagtagtagg ttcgatatct ccagctaaaa tttttaaaaa ggttgatttt ccggcaccat
    13561 tagcaccgat taatccgtaa gtatttcctt ctgtaaattt gatattgaca tcatcaaaaa
    13621 gtttgcgatc actaaaacgt agtgaaacat cagatactgt aagcaatatt tttctcctat
    13681 atgtgtaata tatttattct actagaaaat acagaaatat tcaaattttt atttttcaat
    13741 tttgtgtaaa ttatatttac agtatccttt acacaaatct gtaaaaagca aggctgattt
    13801 attttgataa attacggtta tttcattaaa aaaatgctat aattgaaagg actatatcga
    13861 aggagaacaa aatgactaaa cccattattt taacaggaga ccgtccaaca ggaaaattgc
    13921 atattggaca ttatgttgga agtctcaaaa atcgagtatt attacaggaa gaggataagt
    13981 atgatatgtt tgtgttcttg gctgaccaac aagccttgac agatcatgcc aaagatcctc
    14041 aaaccattgt agagtctatc ggaaatgtgg ctttggatta tcttgcagtt ggattggatc
    14101 caaataagtc aactattttt attcaaagcc agattccaga gttggctgag ttgtctatgt
    14161 attatatgaa tctagtttcg ttagcacgtt tggagcgaaa tccaacagtc aagacagaga
    14221 tttctcagaa aggatttgga gaaagcattc cgacaggatt cttggtctat ccaatcgctc
    14281 aagcagctga tatcacagct ttcaaggcta attatgttcc tgttgggaca gatcagaaac
    14341 caatgattga gcaaactcgt gaaattgttc gttcttttaa caatgcatat aactgtgatg
    14401 tcttggtaga gccggaaggt atttatccag aaaatgagag agcagggcgt ttgcctggtt
    14461 tagatggaaa tgctaaaatg tctaaatcac taaataatgg tatttattta gctgatgatg
    14521 cggatacttt gcgtaaaaaa gtaatgagta tgtatacaga tccagatcat atccgcgttg
    14581 aggatccagg taagattgag ggaaatatgg ttttccatta tctagatgtt tttggtcgtc
    14641 cagaagatgc tcaagaaatt gctgatatga aagaacgtta tcaacgaggt ggtcttggtg
    14701 atgtgaagac caagcgttat ctacttgaaa tattagaacg tgaactgggt cctattcgtg
    14761 agcgccgtat tgaatttgct aaggatatgg gagaagttta taatatgatt caaaaaggta
    14821 gtgaaagagc gcgtgaagtt gcgggtcaaa ccctatctga ggtaaaaggg gcaatgggac
    14881 ttcattactt taactaagtt tattttacaa gaaactatct tttctatctc gaagaaaaga
    14941 tagtttttta tttacccctg taacatttga caaattttta tagaatggta tgatagatac
    15001 aatataaaaa gagtcaagct caaaaagaaa gaaaagagga aacttcgaat gtctaattgg
    15061 gacactaaat ttttgaaaaa aggttttacc ttcgatgatg tattgcttat tccagctgaa
    15121 agtcatgtgt tgcctaacga tgcagattta acaactaaat tggcagataa tttgacttta
    15181 aatatcccaa ttattaccgc tgccatggac acagttacag agagtcaaat ggccattgct
    15241 attgctcgtg caggcggtct cggagttatc cataaaaaca tgtcaattgc tcaacaagca
    15301 gacgaggttc gtaaggtaaa acgttctgaa aatggagtta ttattgatcc gttcttcttg
    15361 acgcctgaac atacaattgc tgaagcagat gagcttatgg gtcgttaccg catcagtggt
    15421 gttccagttg ttgaaacact tgaaaatcgt aaattggttg gtattttgac aaaccgagat
    15481 cttcgtttta tttcagatta taatcaacca atttcaaacc atatgactag tgaaaatctt
    15541 gttactgctc ctgtgggtac ggatcttgca acggctgaga gtattcttca agagcatcgt
    15601 attgaaaaac ttccgttggt cgatgaagaa ggcagtcttt ctggtttgat cactatcaaa
    15661 gatattgaaa aagttattga gtttccaaat gcggctaaag atgagtttgg tcgtcttcta
    15721 gttgcaggtg cagtaggtgt tacttcagat acatttgaac gtgcagaggc tctttttgag
    15781 gcaggagcgg atgcgattgt tattgatact gcacatggtc attctgcagg tgtcttgcgt
    15841 aaaattgccg agattcgtgc tcatttccca gatcggactt tgattgctgg aaatattgct
    15901 actgctgaag gtgcacgtgc cctttatgaa gcgggtgtag acgttgttaa ggttggtatt
    15961 ggaccaggtt ctatctgtac tactcgtgtg attgctggtg ttggtgttcc gcaagtaaca
    16021 gctatctacg atgctgcagc tgttgcgcgc gaatatggta aaacgattat tgctgacggt
    16081 gggatcaagt attctggaga tattgtaaaa gcacttgctg caggtggaaa tgctgttatg
    16141 cttggatcta tgtttgctgg aactgatgaa gctccaggcg aaactgaaat cttccaagga
    16201 cgtaaattca agacttaccg tggtatggga tcaattgctg ctatgaagaa aggttcaagc
    16261 gaccgttatt tccaaggttc tgtcaatgaa gcaaacaagc ttgttccaga aggaattgaa
    16321 ggtcgtgttg cttataaagg agcggcagct gatattgttt tccaaatgat tggtggtatt
    16381 cgctctggta tgggttactg tggtgcagct aaccttaaag aactacacga taatgctcaa
    16441 tttattgaaa tgtctggtgc tggtttgaaa gaaagccatc ctcatgatgt gcaaattact
    16501 aatgaggcac caaattattc tatgtaaaaa acaatgaaaa gaactccagt gaaaacagga
    16561 gttcttttac aatgttgtca atttccattt acagaagctt taccatcctg aatagtgaag
    16621 atacttagat tttctggcag attttgaaga tggtctaagc ttgttgttgt gataaaggtt
    16681 tggattgatt gagaaatcgt ttctaataat tttaactgtc tagtgttgtc aagttcactc
    16741 atcacatcgt caagcagtaa tatcggagat tctgtggtaa tgctttccat taattcgatt
    16801 tctgctaatt ttatcgagag gacgagacta cgatgttgac cttggcttcc gaaactagca
    16861 tccatcccat ttatataaaa agaaatgtca tctcgatgag gaccgacacc agtattcttt
    16921 ttaaataaat ctctggatct acttttttct aaagcaattt tgaaagattc ggataagttt
    16981 tgtttgtcag ttatattgac agaagattga taggatattg acaactcttc gatctgatta
    17041 gagagttcaa aatgtttctt acgcccaaat gattctagtt tttttatgaa atctaagcgg
    17101 tgattcatta cacgacatcc ataatcaact agctgatcat ctaacacaga aaggaatgtt
    17161 tcatctattt tttgatctga ttttaggtaa gtgtttcttt gctttaggat gtggttataa
    17221 ttggttaagt cagataagta gattggctta atttgcccaa gttccatatc aatgaatttt
    17281 cgtcgaatcg aaggtgctcc tttaattagt tgtaaatctt caggagcaaa taagacaaca
    17341 ttcatgtgtc ctacataatc tgaaaggcgt gcctgtttta agtgattaac ttttgttaca
    17401 cggccttttt gtgttagttc gatttctagg ggaatggatc cagttttttt ctgaacgaga
    17461 cctgaaagat gaagttgttc ctcatcaaaa tgaatgagat ttttatctgt tcgagttcga
    17521 tgactacgcg ttaaggctaa aaaatagata gcctctaaca tgtttgtttt tccttgtgca
    17581 ttacgtccca aaaagacatt caatttagga ttaaagtcta ttttcgtttc tttgtaatta
    17641 cgaaaagtct tgagagatag atgttgtagc cacatgatta tctaccaggg aatcgtggag
    17701 cttgttggct tttaggtgat gaagcaggtt tcgatttgtc ttttttaact cccttattca
    17761 tctttttgac aagtttagcg atccgttctt tttcaacttt atcagcttgg tattcatctt
    17821 gttcttcaga agtaggttgt gtcaacaaga tgtcaatgtt catgtcaggg atgtcaactt
    17881 tatcgccaat acgaagtttt tttccacgac gactctctaa ttccctatta aagtaaacag
    17941 aatgttcaga gagaaatgat ttaatagctc ctccgctatg tgtaattcca agttctttga
    18001 gtagtgcttg gagggtaata aattcttcaa ataatttgta ttccataatt cacctcaatc
    18061 tttggtatta taccatattt tcctaaaaat agtgagagag acagcgagaa atgtaagcga
    18121 tttttatttc aaaagtgtta cagggaacaa gaaaatttca ggttttcgtg atataataga
    18181 agtctgtata taaggaggta aatcatggag ttagtgcatg gaatttcaac acattttatc
    18241 caatcaaaaa agtttaaaac aaacaaaatt accgtgcgtt ttaccgctcc attatccctt
    18301 gatacgattg caggtcacat gttgagtgca agtatgctag agactgctaa tcagatgtac
    18361 cccacttctc aagatttgag gagacacttg gccagtctat acggtacaga tatgtcaacc
    18421 aattgtttca gaagagggca aagccacatt atagaattga catttaccta tgttcgtgat
    18481 gagtttttaa gtaggaaaaa cgtgctaacc tctcagattt tggaacttgt aaaagaaact
    18541 cttttttcac ccgtagtagt tgataatggg tttgatccgg ccttatttga aattgagaaa
    18601 aaacaattgc tagcaagttt agcagctgat atggatgatt ctttttattt tgcacataaa
    18661 gaattggata aattgttttt tcatgatgaa cgtcttcaat tggaatatag tgatttacga
    18721 aatcgtattt tagctgaaac tccacaaagt tcttattctt gtttccaaga atttttagcc
    18781 aatgatcgaa tagatttctt tttcctaggt gattttaatg aggttgaaat tcaaaatgta
    18841 ttagaatcat ttggctttaa aggtcgaaaa ggagatgtga aggttcagta ttgtcaacct
    18901 tattctaata tccttcagga aggtatggtt cggaaaaatg tgggacaatc cattttggaa
    18961 ttaggttatc attactgttc taaatatggt gatgagcaac atttacccat gattgtaatg
    19021 aatggtttac ttggtggatt tgctcactct aagctcttta caaatgtccg tgaaaatgct
    19081 ggattagctt ataccatttc aagtgagctt gatttattta gtggattctt gaggatgtat
    19141 gctggtatca atcgagaaaa tcgtaaccag gctcgtaaaa tgatgaataa tcaactgctt
    19201 gatttaaaaa aaggttattt tacagagttt gagttaaatc agaccaagga aatgattcgt
    19261 tggtcgttgt tactttctca agataatcaa tcttcattga ttgaacgtgc ttatcaaaat
    19321 gccttatttg gaaaatcttc agcagacttt aaaagttgga ttgcaaagct tgaacagatt
    19381 gacaaagatg ctatttgtag agtagctaat aatgtgaaac tacaagcgat ttactttatg
    19441 gaaggaatag aatgacaaag gttgtttttg aagaaaaata ctatccagct gtaaaagaaa
    19501 aggtttatcg aactcgtttg gccaacggat tgacagttgc tcttttgcct aaaaaggaat
    19561 ttaaagaggt ttacgggagt gtaactgtac agtttggttc gatagatacg cttgtcacag
    19621 aagttgacgg agatgtaaaa caatatcctg gaggaattgc tcattttctt gaacataaat
    19681 tatttgagag agaagattct agtgatttga tgtcggcttt tacgagtcta ggtgcagata
    19741 gtaatgcctt tacaagcttt acaaaaacaa actatctttt ttcagcaacg gattattttt
    19801 tagaaaattt atatttactt gatgaattgg taacatcagc acactttact gaagcttcca
    19861 ttctgacaga gcaggatatt attcagcaag aacgagaaat gtaccaagat gatccagatt
    19921 cgtgtttatt cttttcaact ttagcgaatt tgtatcctgg tacaccttta gcaactgata
    19981 tagttggaag tgaggagtcc atttcccaaa tcaatctaac taatttgcaa gaaaatttta
    20041 caaagtttta caaacctgta aacatgtctc tgtttttagt tggtaatttt gatgtggagc
    20101 gagtacagga ctattttgaa agcaaagaac tgaaagattc agattttcag gaagtagcaa
    20161 gagaaaagtt gtttttacag cctgtaaagc caacagatag tatgagaatg gaagtatctt
    20221 ctcccaaact agcgattgga gttagaggta agcgagaagt ttctgaagcg gattgctatc
    20281 gacatcatat tttattaaaa ttattgtttg caatgatgtt tggttggact tcggatcgtt
    20341 ttcaaaaatg ttatgaatca ggtaaaattg atgcgtcctt atctctggaa gttgaaataa
    20401 caagtcgctt tcattttgtc atgttgacaa tggatacgaa agagccagtt gctttgtctc
    20461 atcaatttag gaaggctatt cgtaatttta caaaggattt agatattaca gaggaacatt
    20521 tagatattat caaaagagag atgtttggcg aatttttcag tagcatgaac tctcttgaat
    20581 ttattgcaac gcaatatgat gcttttgaaa atggtgagac aatttttgat ttgccgaaaa
    20641 ttttacagga aattacttta gaggatgtcc ttgatgctgg acatcattta atagatgatg
    20701 gtgacatagt tgattttaca atattcccat cgtagtaacc tattataata gacactagaa
    20761 agaagggatg acaagtatga gaaaaaaaac aattggagag gttttacgat tagctagaat
    20821 caatcaggga ttgagtttag atgaattgca gaaaaagaca gaaatccagt tagatatgtt
    20881 ggaagcaatg gaagcagacg atttcgatca acttccaagt cctttttaca cgcgttcttt
    20941 cttgaaaaaa tatgcatggg ctgttgagtt agatgaccaa attgttttgg atgcttatga
    21001 ttctgggagt atgattactt atgaggaagt agatgttgat gaagatgagt tgacaggtcg
    21061 tagacgttca agtaagaaaa agaagaaaaa aatatcattt ttacctttat tttattttat
    21121 cttttttgct ttatcgattt taatttttgt gacttattat gtttggaact atattcaaac
    21181 tcaaccagag gagccttctc tttctaatta cagtgtggtt caatcaacaa gttcaactag
    21241 ctctgttccc cactcctcaa gtagtagttc ttctagtata gaatcagcta taagtgtatc
    21301 aggcgaagga aatcatgtag aaatcgctta taagacaagt aaggaaacag ttaaattgca
    21361 attggcagtt tcagatgtta caagttgggt cagtgtttca gaaagcgaac ttgagggcgg
    21421 tgtaacctta tcgccaaaga agaaaagtgc agaagcaaca gttgcaacta aaagtcctgt
    21481 aacaattacg ttaggtgttg taaaaggtgt tgatttgaca gtagataatc agactgttga
    21541 tttatcgaaa ttaacagctc agactggaca aatcactgta acctttacta aaaattaagg
    21601 aaaaacgaat gaaaaaagaa caaattccca atctcttaac aataggtcga attctcttta
    21661 tacctatttt tatctttatt ttaacgatag gaaattcgat agagagtcat atagttgcag
    21721 ctattatctt tgctgttgcc agtattaccg actatttaga tggatattta gctcgtaaat
    21781 ggaatgtggt cagtaatttt ggtaaatttg cagatcctat ggcggataag ttactagtta
    21841 tgtcggcttt tattatgttg attgagttag gtatggctcc ggcttggatt gttgcagtga
    21901 ttatctgtcg tgagttagct gtgacaggtt taaggctttt attggttgaa actggtggaa
    21961 caattttagc agcagcaatg cctggaaaaa ttaaaacttt tagtcagatg tttgccatta
    22021 ttttcttgct attacattgg actttgcttg gtcaagttct actttatgta gccttatttt
    22081 tcactatcta ctctggctat gactatttca agggtagtgc ctatgtattt aaagggacat
    22141 ttggttcgaa atgaaatcaa taattgatgt aaaaaatctt tcttttcgct ataaagaaaa
    22201 tcagaactac tacgatgtga aggatattac gtttcacgtg aaacgtggag aatggctttc
    22261 gattgtaggg cataatggta gtggtaaatc aacgacggtt cgattaattg atggcttact
    22321 ggaagcagaa tccggagaga ttgtaattga tggccaacgt ttgactgagg aaaatgtttg
    22381 gaatatacgt cgtcaaatcg gtatggtttt tcaaaatcca gacaatcaat ttgttggagc
    22441 gactgttgaa gatgatgttg cttttggttt ggaaaatcag ggactttctc gtcaagaaat
    22501 gaaaaagaga gtggaagaag ctctggcttt agttggcatg ttggacttta aaaagagaga
    22561 gccagcgcgt ctatcaggtg gccaaaagca acgtgtggcc attgcaggtg ttgtagccct
    22621 aagaccagct attttaatct tagatgaagc aacgagtatg ttggatcctg aggggcgtag
    22681 agaacttatt gggacagtaa aaggaattcg aaaagactat gatatgacgg tcatttctat
    22741 tacccatgat ttggaagaag tcgccatgag tgatcgcgta ttggtcatga aaaaagggga
    22801 aattgaatca actagtagtc caagggagct tttctctcga aatgatttag atcaaattgg
    22861 attagacgat ccttttgcta atcaattaaa aaaatctttg agccagaatg gctatgattt
    22921 acctgaaaat tatttgacag aaagtgagct agaggataag ctatgggaat tgctctagaa
    22981 aatgtgaatt ttacatatca agaaggtact cccttagctt cagcagcttt gtcggatgtt
    23041 tctttgacga ttgaagatgg ctcttataca gctttaattg ggcacacagg tagtggtaaa
    23101 tcaactattt tacaactctt aaatggttta ttggtgccaa gtcaagggag tgtgagggtt
    23161 tttgatacct taatcacctc gacttctaaa aataaagata ttcgtcaaat tagaaaacag
    23221 gttggcttgg tatttcagtt tgctgaaaat cagatttttg aagaaacggt tttgaaggac
    23281 gttgcttttg gaccgcaaaa ttttggagtt tctgaagaag atgctgtgaa gactgcgcgt
    23341 gagaaactgg ctctggttgg aattgatgaa tcactttttg atcgtagtcc gtttgagctg
    23401 tcagggggac aaatgagacg tgttgccatt gcaggcatac ttgccatgga gccagctata
    23461 ttagtcttag atgagccaac agctggtcta gatcctctag ggagaaaaga gttgatgacc
    23521 ctgttcaaaa aactccacca gtcagggatg accatcgtct tggtaacgca tttgatggat
    23581 gatgttgctg aatatgcgaa tcaagtctat gtaatggaaa agggacgttt agtaaagggg
    23641 ggcaaaccaa gtgatgtctt tcaagacgtt gtttttatgg aagaagttca gttgggagta
    23701 cctaaaatta cggccttttg taaacgattg gctgatagag gcgtgtcatt taaacgatta
    23761 ccgattaaga tagaggagtt caaggagtcg ctaaatggat agtatgattt tagggcgtta
    23821 tatcccaggg gattcgattg ttcaccgatt ggatccacgt agcaaattgc ttgctatgat
    23881 gctactgatt ttgattgtgt tttgggctaa taaccccttg acgaatctga ttctttttat
    23941 agcgacaggg atatttattg ccttgtcagg agtatctctt tcatttttta ttcagggctt
    24001 gaagtctatg tttttcttga ttgccttcac aactattttt caactatttt tcatttctaa
    24061 tgggaatgtt ttatttgagt tttcgtttgt gagaatcacg gattatgctt tgcaacaagc
    24121 tgggattatt ttttgtcgct ttgtattgat tattttcttt tcaactttgt taaccttaac
    24181 aaccatgcct ttaagtttgg catcagctgt cgaagcttta ttagcacctt taaagcgtgt
    24241 gaaagttcca gttcatgaaa ttggattgat gctgtctatg agtttgcgtt ttgtcccaac
    24301 cttgatggat gatacgactc ggattatgaa tgcacagaaa gctcgtggag tggattttgg
    24361 agaaggaagc atcgttcaaa aagtaaaggc gatgattccc attttgattc ctctttttgc
    24421 gacaagttta aaacgtgcag attccttggc tatcgctatg gaagcgcgtg gctatcaggg
    24481 tggaaaaggc agaagtcaat accgacaatt gaaatggact ctgaaggata cgctgaccat
    24541 tcttgttatt ctcgtacttg gttgttgttt atttttctta aaatcttagt agctttcagg
    24601 aattgataaa aagttactgt aacagttttt gatataaagg taggaatatg aaccgtttta
    24661 aaaaatcaaa atatgtcatt attgtttttg tcactgttct gcttgtgtca gctctcttag
    24721 cgacgactta ttcaagtaca attgtgacaa aattaggaga tggaatctca ttggttgata
    24781 gagttgtaca aaaacctttt cagtggtttg attctgtcaa atcagatttg gctcatttga
    24841 cacgaacata taatgaaaat gaaagtttga agaaacagct ttaccaatta gaagttaaat
    24901 caaatgaggt ggaaagttta aagacagaaa atgaacaact gcgccaattg cttgatatga
    24961 agtctaaatt gcaagccaca aagactttag cagcagatgt tattatgcgt tctccggtat
    25021 cttggaagca ggagttgacc ttagatgcag gtagatcaaa aggtgcttct gagaacatgt
    25081 tagctattgc aaatggtggc ttgattggga gtgtttcaaa agtagaggag aactctacta
    25141 tagtcaacct tctgacaaat acggaaaatg ctgataagat ttctgttaaa attcaacatg
    25201 gctctactac aatttatgga attattattg gctatgacaa ggaaaatgac gttcttaaaa
    25261 ttagccaatt aaatagtaat agcgatatta gtgcgggaga taaggtgact actggtggat
    25321 taggaaactt taacgttgct gatattcctg ttggtgaagt ggttgccaca acgcatagta
    25381 cagactattt gacacgagaa gtaactgtta aattgagtgc agatactcat aatgtagatg
    25441 tgatagaatt agtggggaat tcataatgag acagttgaag cgagttggag tatttttatt
    25501 gcttcctttc tttgttctaa ttgacgccca tattagccag cttctgggct catttttccc
    25561 ccatgtacat ttggctagtc attttctttt tctatttctc ttatttgaga cgatagaagt
    25621 atcagagtat ctctacctag tctattgttt tgttataggc ttggtttatg atgtttactt
    25681 tttccatcta atagggatta caactctctt atttatctta ttgggagcct tccttcataa
    25741 attgaatagt gttattttgt tgaatcgttg gacaagaatg ctagctatga ttgtgctgac
    25801 attcctgttt gaaatgggta gttatctttt ggcttttatg gtagggttga cagtagatag
    25861 catgtcgatt tttatagtct atagcttggt accgacgatg attttaaatt ttttatggat
    25921 tactgttttt caatttattt ttgaaaaata ttatctataa gaacgacata taaatgtaac
    25981 aaaggcgtaa tatttattag gccttttttt ggtatactag tattgtcttt aaaagaagga
    26041 gtatctacgt aatatgaaga aaaaaatctt agcgtcactt ttattaagta cagtaatggt
    26101 ttctcaagta gctgttttaa caactgcgca tgcagaaacg actgatgaca aaattgctgc
    26161 tcaagataat aaaattagta acttaacagc acaacaacaa gaagcccaaa aacaagttga
    26221 ccaaattcag gagcaagtat cagctattca agctgagcag tctaacttgc aagctgaaaa
    26281 tgatagatta caagcagaat ctaagaaact cgagggtgag attacagaac tttctaaaaa
    26341 cattgtttct cgtaaccaat cgttggaaaa acaagctcgt agtgctcaaa caaatggagc
    26401 cgtaactagc tatatcaata ccattgtaaa ctcaaaatca attacagaag ctatttcacg
    26461 tgttgctgca atgagtgaaa tcgtatctgc aaacaacaaa atgttagaac aacaaaaggc
    26521 agataaaaaa gctatttctg aaaaacaagt agcaaataat gatgctatca atactgtaat
    26581 tgctaatcaa caaaaattgg ctgatgatgc tcaagcattg actacgaaac aggcagaact
    26641 aaaagctgct gaattaagtc ttgctgctga gaaagcgaca gctgaagggg aaaaagcaag
    26701 tctattagag caaaaagcag cagctgaggc agaggctcgt gcagctgcgg tagcagaagc
    26761 agcttataaa gaaaaacgag ctagccaaca acaatcagta cttgcttcag caaacactaa
    26821 cttaacagct caagtgcaag cagtatctga atctgcagca gcacctgtcc gtgcaaaagt
    26881 tcgtccaaca tacagtacaa acgcttcaag ttatccaatt ggagaatgta catggggagt
    26941 aaaaacattg gcaccttggg ctggagacta ctggggtaat ggagcacagt gggctacaag
    27001 tgcagcagca gcaggtttcc gtacaggttc aacacctcaa gttggagcaa ttgcatgttg
    27061 gaatgatggt ggatatggtc acgtagcggt tgttacagct gttgaatcaa caacacgtat
    27121 ccaagtatca gaatcaaatt atgcaggtaa tcgtacaatt ggaaatcacc gtggatggtt
    27181 caatccaaca acaacttctg aaggttttgt tacatatatt tatgcagatt aatttacaga
    27241 gggactcgaa tagagccctc ttttcaggtt ttaccgtgac aatccctatt aaaaattata
    27301 tcaaaatagc ttgaaaatat tggaaaagta tggtagaatg aaaattgtcg tgtgaacgat
    27361 aatactcatt cttgatgaat tgtgaagcag ttgcccttgg gtcgttttgc gagttgaagt
    27421 caagaagagg aaaaaaacaa aaaggagaaa tactcatggc agtaatttca atgaaacaac
    27481 ttcttgaggc tggtgtacac tttggtcacc aaactcgtcg ctggaatcct aagatggcta
    27541 agtacatctt tactgaacgt aacggaatcc acgttatcga cttgcaacaa actgtaaaat
    27601 acgctgacca agcatacgac ttcatgcgtg atgcagcagc taacgatgca gttgtattgt
    27661 tcgttggtac taagaaacaa gcagctgatg cagttgctga agaagcagta cgttcaggtc
    27721 aatacttcat caaccaccgt tggttgggtg gaactcttac aaactgggga acaatccaaa
    27781 aacgtatcgc tcgtttgaaa gaaattaaac gtatggaaga agatggaact ttcgaagttc
    27841 ttcctaagaa agaagttgca cttcttaaca aacaacgtgc gcgtcttgaa aaattcttgg
    27901 gcggtatcga agatatgcct cgtatcccag atgtgatgta cgtagttgac ccacataaag
    27961 agcaaatcgc tgttaaagaa gctaaaaaat tgggaatccc agttgtagcg atggttgaca
    28021 ccaatactga tccagatgat atcgatgtaa tcatcccagc taacgatgac gctatccgtg
    28081 ctgttaaatt gatcacagct aaattggctg acgctattat cgaaggacgt caaggtgagg
    28141 atgcagtagc agttgaagca gaatttgcag cttcagaaac tcaagcagat tcaattgaag
    28201 aaatcgttga agttgtagaa ggcgacaacg cttaatttat acaaatagta attacctagg
    28261 agggcggggc ttagcccggc tctcctattt tcaaaaaata taggagaatt aaaatggcag
    28321 aaattacagc taaacttgta aaagagttgc gtgaaaaatc tggtgccggt gttatggacg
    28381 ctaaaaaagc gcttgtagaa acagacggtg acatcgaaaa agcgattgaa ttgcttcgtg
    28441 aaaaaggtat ggctaaggca gctaagaaag ctgaccgtgt tgctgcagaa ggtttgactg
    28501 gtgtttatgt taacggtaat gttgcagcag ttattgaagt aaacgctgaa actgacttcg
    28561 ttgcaaaaaa cgctcaattc gttgaattgg taaatactac agctaaagtc attgctgaag
    28621 gaaaacctgc taacaacgaa gaagctcttg ctttgataat gccttcaggt gaaactcttg
    28681 aagctgcata cgtatctgca acagcaacta tcggagagaa aatctcattc cgtcgctttg
    28741 cattgattga aaaaacagac gcacaacact ttggagcata ccaacataac ggtggacgta
    28801 tcggtgttat ttcagttgtt gaaggtggag acgaagcact tgctaaacaa ttgtcaatgc
    28861 acatcgcagc gatgaaacca acagttcttt cttacaaaga attggatgag caattcgtta
    28921 aagatgagtt ggcacaattg aatcacgtta tcgaccaaga caacgaaagc cgtgcaatgg
    28981 ttaataaacc agctcttcca cacttgaagt atggatcaaa agctcaatta actgatgatg
    29041 ttattgctca agctgaagct gacatcaaag ctgaattggc tgcagaaggt aaaccagaaa
    29101 aaatctggga caaaattatt ccaggtaaaa tggatcgctt catgcttgat aacactaaag
    29161 ttgaccaagc ttacacactt cttgcacaag tttacatcat ggatgacagc aagacagttg
    29221 aagcatacct tgaatcagtt aacgcttcgg tagttgagtt tgctcgcttt gaagttggtg
    29281 aaggtatcga gaaagctgca aacgacttcg aagctgaagt tgcagctaca atggcagcag
    29341 ccttgaataa ctaataatag aaaggaagca aattgcttcc ttttttgtat agggcttaga
    29401 tttttcctga aattgttttt tccccagcct cactcgatta gaataattaa aacaaaaagc
    29461 cctataataa gggctaagtg catttaggag actatacttc aaattcatag taagcgcgtc
    29521 ataacaaggt atctatccta attccccaac ttccagtata ctagataaaa aataattatc
    29581 ggaggaaagg tattgtacta tgataattca actaagtgat ttaggtcaag ttcaccttgt
    29641 ttgtgacaag acagatatga ggtagggaat agactcatta gcctatgtag ttaaaaccca
    29701 ctttgaattg gattctttct ccggtcaagt ctttctcttt tgtggtgaac gtaaagaccg
    29761 ctttaaagcc ctttactggg atggtcaagg attttggcta ctatataaac gctttgagaa
    29821 cggaaaactg acttggctaa gtacagaaaa ggatgtcaaa gctctcgcac ctgaacaagt
    29881 agattggctt atgaagggct tttctatcac tccaaaaata tagtagattg aaactagaat
    29941 agtacacctc tgcttctaaa acattgttag aaatcgattt gattgtcctg atcgatttgt
    30001 cctgttctta tttcatttta ctataaatcc atcagaaagt tgtgatttct attgaaatga
    30061 ggactttctt tttacactca tctgctttca aaaagcattc tagtccatct ccgattaacg
    30121 atggacttta tcacctcctt ctccagtcct tgtatgacat cttccaaagt tcgaaaggct
    30181 ttattcttaa atccacgttt acgaatctct ttccatactt gttcaatggg gttcatctct
    30241 ggtgtgtatg gaggaataaa tgcaaagcca atattagtcg gaatctttaa ggtacttgat
    30301 ttatgccata tagcattgtc cataacgagt aaaagataat catctggata agcttgtgaa
    30361 agctcctatt cctaaagccc ctttagcgca tagctttggc tcagcttcta ttatcgctca
    30421 caccatccat cagaagttta atctgaaggt acccaattat cgccaagaag aagattgggc
    30481 taagatgggt ttaccaatca cacgcaagga aatctctaat tggcatatca agacgagtca
    30541 atactatttg gagcccctct ataacctctt gcgagagaga ctattgactc agcccttact
    30601 tcatgcggat gaaacttctt atagggtgct agagagtgat agtcagctga cttactattg
    30661 gacttttttg tctgggaaag ctgagaaaca agggattacg ctttaccatc atgtcctaat
    30721 cgatttgttc atatcttatt tcaatccatt ataaatagtg agaaatatct atcctatctt
    30781 ctagaatgtc ttccaaacgt ggaaactctc gtaaacaaag aggttttaga ggcttattta
    30841 ccatggacta aaattgtaca agaaaagtgc aaataagaaa tctccagatt aggaactatc
    30901 cgtgagttct ctagtctgga gatttttcaa tatacttcgt tattggacgg ttacaattca
    30961 taaagtgctg tagagagata acgttcaccg ttatctggtg ctagggcaag gactttttta
    31021 cctgtaccta attttttggc aacctcgatg gctccgtaga tagctgcagc tgaggaaatc
    31081 cctacaagga agccttcttt tccaccaatt tcacgtccga gtgcaagagc gtcatctgat
    31141 gttacacgaa cgataccatt ataggcttta gtatcaagtg tatcaggaat aaatccagct
    31201 gagatacctt gaattttgtg aggaccaggt ttttcaccag atagaatagc agattcatct
    31261 gcttctactg caaaaacttg aatgttagaa ttttctgatt tgagtgcatg agaaacacca
    31321 gaaatcgttc caccggtacc tactccagca acaaaggcat ctaatccatc tttaccgaaa
    31381 gcagctagta tctcagctcc tgttgttctt tcgtgtactt ctggattagc tggattgtca
    31441 aattgaagag gaaggaaacc atcacgttca gcagcgattt cttgagcctt agcaatagca
    31501 cctttcattc cctcgctacc aggagttagg acgagttcag caccataagc ttggataatt
    31561 ttacgtcgtt ctacactcat agtttcaggc ataacgatga cgactttata ccctttagca
    31621 gcacctaccc atgaaagtcc aataccagtg tttccacttg ttgcttcaac aatagtagaa
    31681 ccaggtttca gaataccatc ttgttcagct ttttcaatca tgctaagggc aatacggtct
    31741 tttacagatg aaccaggatt aaatgcttca agctttatat agacgtctgc agcaccttct
    31801 ggcacgatgt tgttaagttt aacaatcggt gtttgaccga ttaattcagt aatgttgtta
    31861 taaatagaca tatgaatacc tctttgtata agatatcttt agtataacgc tatccatacc
    31921 atttgtaaaa tatagaaatc ctatcgaagc gataggattt ctatatatca tagatcaaag
    31981 tcattaattt tcaagtgatt gcgttcagct aattctagta aataggtgtg aaggaaaacg
    32041 ctatcaggtt tcgtttgaat tgcttcattt tctagtatat tttggtacgc atctttttat
    32101 tttgctcgct aaagtagttg tgagaatgtc aacgaaacgc tgtattattc attgtttaca
    32161 ctaagtttac aggaacttca acctctcgta aaccttggtc agttaaagtg acttttccat
    32221 taaaaaactc cacaagtgca gctttaatag tttctttttc ttctttatca acataaatca
    32281 tcgtatcgac ttgatctgta aagtttgtat ccagctccat gagatcatgt tctttaagga
    32341 agttactgta ctcttggtac tgagcataag acatttgaat agcaatgcca gcctgttctt
    32401 ttatttcaat aataccaatt tctttgacag ctaaggcgac actgccggcg taagcacgaa
    32461 ttagtcctcc agcgcctagt ttaataccac caaagtagcg tgtcacgacc acacagacat
    32521 tggtgagatt gtgattttct agtaccccaa gcatgggaac accagcagta ccactaggct
    32581 caccattatc acttgtacgt ttaatttcac tacgttctcc aataataaag gcagagcagt
    32641 tatgtgtcgc tttgtagtgt tcttttttga tggcagtaat gaagtcacga gcctcttctt
    32701 cgctataaac acgcttggca tggcagataa agcgagattt ttttatttct tcttggactt
    32761 ggccgtcctc tttaattgtc ctaaattcca tgatttaatt gtactaaaaa ataatctaaa
    32821 gtgctagttt ttacgaatag agaagtatga aagtaaattt agattatctc ggtcgtttat
    32881 ttactgagaa tgaattaaca gaagaagaac gtcagttggc ggagaaactt ccagcaatga
    32941 gaaaggagaa ggggaaactt ttctgtcaac gttgtaatag tactattcta gaagaatggt
    33001 atttgcccat cggtgcttac tattgtcgag agtgcttgct gatgaagcga gtcagaagtg
    33061 atcaaacttt atactatttt ccgcaggagg attttccgaa gcaagatgtt ctcaaatggc
    33121 gcggccaatt aactcctttt caagagaagg tgtcagaggg actgcttcaa gcagtagaca
    33181 agcaaaagcc aaccttagtt catgcggtaa caggagctgg aaagacagaa atgatttatc
    33241 aagtagtggc taaagtgatc aatgcgggtg gtgcagtgtg tttggctagt cctcgcatag
    33301 atgtttgttt ggagctgtac aagcgcctgc aacaggattt ttcttgcggg atagctttgc
    33361 tacatggaga atcggaacct tattttcgaa caccactagt tgttgcaaca acccatcagt
    33421 tattgaagtt ttatcaagct tttgatttgc tgatagtgga tgaagtagat gcttttcctt
    33481 atgttgataa tcccacgctt taccacgctg tcaagaatag tgtaaaggag aatggattga
    33541 gaatcttttt aacagcgact tcgaccaatg agttagataa aaaggtccgt ttaggagaac
    33601 taaaaagact gagtttaccg agacggtttc atggaaatcc gttgattatt ccaaaaccaa
    33661 tttggttatc ggattttaat cgctacttag acaagaatcg tttgtcacca aagttaaagt
    33721 cctatattga gaagcagaga aagacagctt atccgttact catttttgct tcagaaatta
    33781 agaaagggga gcagttagaa gaaatcttac aggagcaatt tccaaatgag aaaattggct
    33841 ttgtatcttc tgtaacagag gatcgattag agcaagtaca agcttttcga gatggagaac
    33901 tgacaatact tatcagtacg acaatcttgg agcgtggagt taccttccct tgtgtggatg
    33961 ttttcgtagt agaggccaat catcgtttgt ttaccaagtc taatttgatt cagattggtg
    34021 gacgagttgg acgaagcatg gatagaccga caggagattt gcttttcttc catgatgggt
    34081 taaatgcttc aatcaagaag gcgattaagg aaattcagat gatgaataag gaggctggtc
    34141 tatgaagtgc ttgttatgtg ggcagactat gaagactgtt ttaactttta gtagtctctt
    34201 acttctgagg aatgatgact cttgtctttg ttcagactgt gattctactt ttgaaagaat
    34261 tggggaagag aactgtccaa attgtatgaa aacagagttg tcaacaaagt gtcaagattg
    34321 tcaactttgg tgtaaagaag gagttgaagt cagtcataga gcgattttta cttacaatca
    34381 agctatgaag gattttttca gtcggtataa gtttgatgga gacttcctgt taagaaaagt
    34441 tttcgcttca tttttaagtg aggagttgaa aaagtacaaa gagtatcaat ttgttgtaat
    34501 tcccctaagt cctgatagat atgctaatag aggatttaat caggttgagg gcttggtaga
    34561 ggcagcaggc tttgagtatc tggatttatt agagaaaaga gaagagggag ccagttcttc
    34621 taaaaatcgt tcagagcgct tggggacaga acttcctttc tttattaaaa gtggagtcac
    34681 tattcctaaa aaaatcctac ttatagatga tatctatact acaggagcaa ctataaatcg
    34741 tgttaagaaa ctgttggaag aagctggtgc taaggatgta aaaacatttt cccttgtaag
    34801 atgaggaaaa aatttgcaaa aatagaatga aagcgttata ataaaatcat aaaaacaaaa
    34861 atgtttagaa agaaggtact catatgatta aatatagtat ccgtggtgaa aacctagaag
    34921 taacagaagc aattcgtgat tatgtagttt ctaaactcga aaagatcgaa aagtacttcc
    34981 aaccagaaca agagttggat gcccgaatta acttaaaagt ttatcgtgaa aaaacggcta
    35041 aagtggaagt aacgattccg cttggatcta ttactctccg cgcagaagat gtatctcaag
    35101 atatgtatgg ttcaattgac cttgtaactg ataaaattga acgtcagatt cgtaaaaata
    35161 aaacaaaaat cgagcgtaaa aataaaaata aggtagcaac tggtcaatta tttacagatg
    35221 ctttggtgga agattcaaat gttgtccagt ctaaagttgt tcgttcaaaa caaattgatt
    35281 taaaaccaat ggatttggaa gaagcaattc tacaaatgga tttattgggg catgatttct
    35341 ttatctatgt ggatgttgaa gatcaaacaa ccaatgtgat ttatcgtcgt gaggatggcg
    35401 aaattggttt gttagaggtt aaagaatctt aatttcaata tgtgtaaagg taggtttact
    35461 gaattgtaaa ctaccttttt cttataattg atagaattac tgattacact tttaaaaagt
    35521 cgctttttga ggggtattat ggtataatgg gtgccaagag gttttgaatg aaaaaatttt
    35581 atgtaagtcc aatttttcct attctagtag gattgattgc gtttggagtc ttatccactt
    35641 tcattatttt tgttaataat aatctgttga cggttttaat tttgtttctt tttgtaggag
    35701 gctatgtttt tttatttaag aaactgagag tgcattatac aaggagtgat gtagaacaga
    35761 tacagtatgt aaaccaccaa gcggaagaaa gtttgacagc tctattggaa cagatgcctg
    35821 taggtgttat gaaattgaat ttatcttctg gagaggttga gtggtttaat ccctatgctg
    35881 aattgatttt gaccaaggaa gatggtgatt ttgatttaga agctgttcaa acgattatca
    35941 aggcttcagt aggaaatccg tctacttatg ccaagcttgg tgagaagcgt tatgctgttc
    36001 atatggatgc ttcttccggt gttttgtatt ttgtagatgt atccagggaa caagccataa
    36061 cagatgaatt ggtaacaagt cgaccagtga ttgggattgt ctctgtggat aattatgatg
    36121 atttggagga tgcaacttct gagtcagata ttagtcaaat caatagtttt gtagctaatt
    36181 ttatatcaga gttttcagaa aaatacatga tgttttctcg tcgggtaagt atggatcgat
    36241 tttatctatt tactgactac acggtgcttg agggcttgat gaatgataaa ttttctgtta
    36301 ttgatgcttt cagagaagag tcgaaacaga gacagttgcc cttgacctta agtatgggat
    36361 tttcttatgg cgatggaaat catgatgaga tagggaaagt tgctttgctc aatttgaact
    36421 tggctgaagt acgtggtggc gaccaggtgg ttgttaagga aaacgacgaa acgaaaaatc
    36481 cagtttattt tggtggtggg tctgctgctt caatcaagcg tacacggact cgtacgcgcg
    36541 ctatgatgac agctatttca gataagattc ggagtgtaga tcaggttttt gtagtcggtc
    36601 acaaaaattt agacatggat gctttgggct ctgctgtagg tatgcagttg ttcgccagca
    36661 atgtgattga aaatagctat gctctttatg atgaagaaca aatgtctcca gatattgaac
    36721 gagctgtttc attcatagaa aaagaaggag ttacgaagtt gttgtctgtt aaggatgcaa
    36781 tggggatggt gaccaatcgt tctttgttga ttcttgtaga ccattcaaag acagccttaa
    36841 cattatcaaa agaattttat gatttattta cccaaaccat tgttattgac caccatagaa
    36901 gggatcagga ttttccagat aatgcggtca ttacttatat cgaaagtggt gcaagtagtg
    36961 ccagtgagtt ggtaacggaa ttgattcagt tccagaattc taagaaaaat cgtttgagtc
    37021 gtatgcaagc aagtgttttg atggctggta tgatgttgga tactaaaaat ttcacctcgc
    37081 gagtaactag tcggacattt gatgttgcta gctatctcag aacgcgcgga agtgatagta
    37141 ttgctatcca ggaaatcgct gcgacagatt ttgaagaata tcgtgaggtc aatgaactta
    37201 ttttacaggg gcgtaaatta ggttcagatg tactaatagc agaggctaag gacacgaaat
    37261 gctatgatac agttgttatt agtaaggcag cagatgccat gttagccatg tcaggtattg
    37321 aagcgagttt tgttcttgcg aagaatacac aaggatttat ctctatctca gctcgaagtc
    37381 gtagtaaact gaatgtacaa cggattatgg aagagttagg cggtggaggc cactttaatt
    37441 tggcagcagc tcaaattaaa gatgtaacct tgtcagaagc aggtgaaaaa ctgacagaaa
    37501 ttgtattaaa tgaaataaag gaaaaggaga aagaagaatg aaagtaatct ttttagcaga
    37561 tgttaaagga aaaggtaaaa aaggcgaaat taaggaagta ccaacagggt atgcgcaaaa
    37621 ctttcttatc aaaaagaatc tagccaaaga agcgactgct caagctgtag gtgaacttcg
    37681 tggtaaacaa aaatcggaag aaaaagctca cgctgagatg attgcagaag gaaaagcaat
    37741 taaagcacaa cttgaagcag aagaaactgt tgtagaattt gttgaaaaag ttggtccaga
    37801 tggtcgtacc tttggttcta ttaccaataa gaagattgca gaagaattgc aaaagcaatt
    37861 tggaattaag attgataaac gtcatattca agtacaagct ccgattcgag cggttggttt
    37921 gattgatgtg ccagtgaaaa tctatcaaga tatcacaagt gtaatcaatc ttcgtgtgaa
    37981 agaaggataa gtttacacct tcttgacaag attgtaaaag gaagggaagt ctgatggcag
    38041 aagtagaaga gttacgagta caacctcaag atatcttagc tgagcaatcc gttttagggg
    38101 ctatctttat tgatgagagt aaacttgttt ttgtgcgaga atacattgag tctcgggact
    38161 tttttaagta tgcccatcgt ttgattttcc aagccatggt cgatttatcc gatcgtggtg
    38221 atgccataga tgcaacaacg gttcgtacta tccttgataa tcaaggtgat ttacagaata
    38281 ttggtggctt gtcttacttg gttgagattg ttaattctgt gccaacttct gctaatgcgg
    38341 agtattatgc taagattgtt gcagaaaaag caatgctacg tcgtttaatt gccaagttga
    38401 cagagtctgt caaccaagct tacgaagcgt cacaaccagc tgatgaaatt attgctcagg
    38461 cagaaaaagg gctgattgat gtcagtgaaa atgcaaatcg aagcgggttt aagaacattc
    38521 gagatgtgtt gaatctcaac tttggaaatc tggaagctcg ctcgcaacaa acgaccgata
    38581 ttacaggtat tgcgacaggt tatcgtgatt tggatcatat gacaacagga cttcatgagg
    38641 aggagttgat tatcttagca gctcgtccag cagttggtaa gacagcattt gccttgaata
    38701 tcgctcagaa cattgggact aagttggaca aaacggttgc tattttttca ctcgaaatgg
    38761 gtgcggaaag cttggtagat cgtatgttag ctgcagaagg cttggtggag tcacattcta
    38821 tccgtacagg gcaattgaca gatgaggagt ggcaaaaata tactattgct cagggtaatc
    38881 tagctaacgc cagtatctat atcgatgata cgccaggtat tcggattaca gagattcgtt
    38941 ctcgttctcg taaattggct caagaaactg gaaatcttgg tttgattttg atagactatt
    39001 tacaacttat cacgggaact ggtcgagaaa atcgtcaaca agaagtttct gaaatttctc
    39061 gtcagttgaa aatactagcc aaggaattga aggttccagt aatcgctctg agtcagcttt
    39121 ctcgtggtgt agaacaacgt caggacaaga gaccggtctt gtctgatatt cgtgaatctg
    39181 ggtctattga gcaggacgct gatatcgtag cttttctcta tcgcgatgac tactatgaac
    39241 gtggtggtga agaagaggag ggtatcccaa ataataaggt ggaagttatt atcgagaaaa
    39301 accgtagtgg agctcgtgga acagtggaat tgattttcca aaaagaatac aataaatttt
    39361 caagtatctc aaagagggag gcataagatg tcagatgcat ttacagatgt agccaagatg
    39421 aaaaaaatca aagaagaaat caaggcacat gagggacaag tcgtagaaat gactttggag
    39481 aatggtcgta agcgccaaaa aaatagattg ggtaagctaa ttgaagttta tccatcccta
    39541 tttattgtgg agtttgggga tgtggaagga gataaacaag ttaatgttta cgttgaatcc
    39601 tttacttact cagatattct tacagaaaag aatttgattc attatcttga ctaaagtgag
    39661 aaattttctc actttttctt ttttctccga ataatttagg tgaaggcaat catcgcttta
    39721 tattattttt caaggaggaa gaatgaaaat tttaccgttt atagcaagag gaacaagtta
    39781 ttacttgaag atgtcagtta aaaagcttgt tcctttttta gtagtaggat tgatgctagc
    39841 agctggtgat agtgtctatg cctattccgg aggaaatgga tcgattgcgc gtggggatga
    39901 ttatcctgct tattataaaa atgggagcca ggagattgat cagtggcgca tgtattctcg
    39961 tcagtgtact tcttttgtag cctttcgttt gagtaatgtc aatggttttg aaattccggc
    40021 agcttatgga aatgcgaatg aatggggaca tcgtgctcgt cgggaaggtt atcgtgtaga
    40081 taatacaccg acgattggtt ccattacttg gtctactgca ggaacttatg gtcatgttgc
    40141 ctgggtgtca aatgtaatgg gagatcagat tgagattgag gaatataact atggttatac
    40201 agaatcctat aataaacgaa ttataaaagc aaacacgatg acaggattta ttcattttaa
    40261 agatttggat ggtggcagtg ttgggaatag tcaatcctca acttcaacag gcggaactca
    40321 ttattttaag accaagtctg ctattaaaac tgaaccccta gttagtgcaa ctgtgattga
    40381 ttactattat cctggagaga aggttcatta tgatcaaatt ctcgaaaaag acggctacaa
    40441 gtggttgagt tatacggctt ataacggaag tcgtcgctat atacagctag agggagtgac
    40501 ttcttcacaa aattatcaga atcaatcagg aaatatctct agctatggat ccaataatag
    40561 ttcaactgtc ggttggaaga aaataaatgg tagttggtat catttcaaat caaatggttc
    40621 taaatcaaca ggatggctga aagacggttc tagctggtat tatttgaaat tatctggtga
    40681 aatgcagaca ggatggttaa aggaaaatgg tttgtggtat tatctgggta gttcaggggc
    40741 aatgaaaaca ggctggtacc aggtctctgg taagtggtat tattcttact cttcaggcgc
    40801 cttagctgtt aatacgacgg tggatggcta cagagtaaac agtgatggag aacgagtata
    40861 gaaaattgga gtaggagaaa tttcctgctc ttttctgtaa gcagtttcct tgacattttt
    40921 cttattttgc gctatcatat atacatataa tatatgggag tctgtgtaca gtctgagagg
    40981 aagtgttaaa cttcgaccgc acctgatctg ggtaatgcca gcggagggaa cgatacttag
    41041 tctaattttg caccttttcc atgtatggta aaggtttttc ttttttttaa aaggaaaacg
    41101 agaagaggag gttcttatga aagcaagcat tgccttgcaa gttttacccc tagcacaggg
    41161 gattgatcgg atagctgtta ttgatcaggt cattgcttat ctgcaaactc aagaagtgac
    41221 gatggtagtg acaccatttg aaacggtctt ggaaggggag tttgatgagc ttatgcgcat
    41281 tctaaaagaa gcgctggaag tggcagggca ggaggcagac aatgtctttg ccaatgtcaa
    41341 aataaatgta ggagagattt taagtattga tgagaaactt gaaaagtata ctgagacgac
    41401 acattagtct attgggcttt ctcggagtat tgtcaatctg gcagttagca ggttttctta
    41461 aacttctccc caagtttatc ctgccgacac ctcttgaaat tctccagccc tttgttcgtg
    41521 acagagaatt tctctggcac catagctggg cgaccttgag agtggcttta ctggggctga
    41581 ttttgggagt tttgattgcc tgtcttatgg ctgtgctcat ggatagtttg acttggctca
    41641 atgacctgat ttaccctatg atggtggtca ttcagaccat tccgaccatt gccatagctc
    41701 ctatcctggt tttgtggctg ggttatggga ttttgcccaa gattgtcttg attatcttaa
    41761 caacaacctt tcccatcatc gttagtattt tggacggttt taggcattgc gacaaggata
    41821 tgctgacttt gtttagtctg atgcgagcaa acccttggca aatcctgtgg cattttaaaa
    41881 tcccggttag cctgccttac ttttatgcag gtctgagggt cagtgtctcc tacgccttta
    41941 tcacaactgt ggtatctgag tggttgggag gttttgaagg tcttggtgtt tatatgattc
    42001 agtctaaaaa actgtttcag tatgatacca tgtttgccat tattattctg gtgtcgatta
    42061 tcagtctttt gggtatgaag ctggtcgata tcagtgaaaa atatgtgatt aaatggaaac
    42121 gtacttaaaa tagagcgttt ttgaaaaaga aaagaggaaa tcaaaatgaa gaaaacatgg
    42181 aaagtgtttt taacgcttgt aacagctctt gtagctgttg tgcttgtggc ctgtggtcaa
    42241 ggaactgctt ctaaagacaa caaagaggca gaacttaaga aggttgactt tatcctagac
    42301 tggacaccaa ataccaacca cacagggctt tatgttgcca aggaaaaagg ttatttcaaa
    42361 gaagctggag tggatgttga tttgaaattg ccaccagaag aaagttcttc tgacttggtt
    42421 atcaacggaa aggcaccatt tgcagtgtat ttccaagact acatggctaa gaaattggaa
    42481 aaaggagcag gaatcactgc cgttgcagct attgttgaac acaatacatc aggaatcatc
    42541 tctcgtaaat ctgataatgt aagcagtcca aaagacttgg ttggtaagaa atatgggaca
    42601 tggaatgacc caactgaact tgctatgttg aaaaccttgg tagaatctca aggtggagac
    42661 tttgagaagg ttgaaaaagt accaaataac gactcaaact caatcacacc gattgccaat
    42721 ggcgtctttg atactgcttg gatttactac ggttgggatg gtatccttgc taaatctcaa
    42781 ggtgtagatg ctaacttcat gtacttgaaa gactatgtca aggagtttga ctactattca
    42841 ccagttatca tcgcaaacaa cgactatctg aaagataaca aagaagaagc tcgcaaagtc
    42901 atccaagcca tcaaaaaagg ctaccaatat gccatggaac atccagaaga agctgcagat
    42961 attctcatca agaatgcacc tgaactcaag gaaaaacgtg actttgtcat cgaatctcaa
    43021 aaatacttgt caaaagaata cgcaagcgac aaggaaaaat ggggtcaatt tgacgcagct
    43081 cgctggaatg ctttctacaa atgggataaa gaaaatggta tccttaaaga agacttgaca
    43141 gacaaaggct tcaccaacga atttgtgaaa taatgacaga aattagacta gagcacgtca
    43201 gttatgccta tggtcaggag aggattttag aggatatcaa cctacaggtg acttcaggcg
    43261 aagtggtttc catcctaggc ccaagtggtg ttggaaagac caccctcttt aatctaatcg
    43321 ctgggatttt agaagttcag tcagggagaa ttgtccttga tggtgaagaa aatcccaagg
    43381 ggcgcgtgag ttatatgttg caaaaggatc tgctcttgga gcacaagacg gtgcttggaa
    43441 atatcattct gcccctcttg attcaaaagg tggataaggc agaagctatt tcccgagcgg
    43501 ataaaattct tgcgaccttc cagctgacag ctgtaagaga caagtatcct catgaactta
    43561 gcggtgggat gcgccagcgt gtagccttac tccggaccta cctttttggg cacaagctct
    43621 ttctcttaga tgaggccttt agcgccttgg atgagatgac aaagatggaa ctccacgctt
    43681 ggtatcttga gattcacaag cagttgcagc taacaaccct gatcatcacg catagtattg
    43741 aggaggccct caatctcagc gaccgcatct atatcttgaa aaatcgccct gggcagattg
    43801 tttcagaaat taaactagat tggtctgaag atgaggacaa ggaagtccaa aagattgcct
    43861 acaaacgtca aatcttggca gaattaggct tagataagta gaaaaatagg gagttggtga
    43921 agattatcct ttaccagcgc cctttttctt ttaaaaatga gaaaatttcg gtataatagt
    43981 caaacaaggt caaggtttaa agagagaggt gggtttgtta tgagatttaa aaatacatcg
    44041 gatcatattg aggcctacat caaggcgatt ttagatcaat ctggtatcgt ggagttgcaa
    44101 cggagtcagt tggcagatac ctttcaggtt gttcctagtc agattaacta cgtgatcaag
    44161 acacgcttta cggaaagtag aggctacttg gttgaaagta agcgtggtgg cggaggctac
    44221 attcgtatag gacggattga gttttctagt catcatgaaa tgctccggga gctgctttac
    44281 tcgattggtg agcgagtcag tcaagaaatt tatgaggata ttctccagct tttggttgag
    44341 caggaattga tgaccaagca ggagatgaat ttgctagaat cagtagcttt ggatcgcgtt
    44401 ttaggagaag aagctccagt tgttcgagca aacatgctac gtcagatcat acaagaggta
    44461 gatagaaaag ggaagtaaga tgaactattc aaaagcattg aatgaatgta tcgaaagtgc
    44521 ctacatggtt gctggacatt ttggagctcg ttatctagag tcttggcact tgttgattgc
    44581 catgtctaat cacagttata gtgtagcagg ggcaacttta aatgattatc cgtatgagat
    44641 ggaccgttta gaagaggtgg ctttggaact gactgaaacg gactatagcc aggatgaaac
    44701 ctttacggaa ttgccgttct cccgtcgttt gcaggttctt tttgacgaag cagagtatgt
    44761 agcgtcagtg gtccatgcta aggtgctagg gacagagcac gtcctctatg cgattttgca
    44821 tgatggcaat gccttggcga ctcgtatctt ggagagggct ggattttctt atgaagacaa
    44881 gaaagatcag gtcaagattg ctgctcttcg tcgaaattta gaagaacggg caggctggac
    44941 tcgtgaagat ctcaaggctt tacgccaacg ccatcgtaca gtagctgaca agcaaaattc
    45001 tatggccaat atgatgggca tgccgcagac tcctagtggt ggtctcgagg actatacgca
    45061 tgatttgaca gagcaagcgc gttctggcaa gttagaacca gtcatcggtc gggacaagga
    45121 aatctcacgt atgattcaaa tcttgagccg gaagactaag aacaaccctg tcttggttgg
    45181 ggatgctggt gtcgggaaaa cagctctggc gcttggtctt gcccagcgta ttgctagtgg
    45241 tgacgtgcct gcggaaatgg ctaagatgcg cgtgttagaa cttgatttga tgaatgtcgt
    45301 tgcagggaca cgcttccgtg gtgactttga agaacgcatg aataatatca tcaaggatat
    45361 tgaagaagat ggccaagtca tcctctttat cgatgaactc cacaccatca tgggttctgg
    45421 tagcggaatt gattcgactc tggatgcggc caatatcttg aaaccagcct tggcgcgtgg
    45481 aactttgaga acggttggtg ccaccactca ggaagaatat caaaaacata tcgaaaaaga
    45541 tgcggcactt tctcgtcgtt tcgctaaagt gacgattgaa gaaccaagtg tggcagatag
    45601 tatgactatt ttacaaggtt tgaaggcgac ttatgagaaa catcaccgtg tacaaatcac
    45661 agatgaagcg gttgaaacag cggttaagat ggctcatcgt tatttaacca gtcgtcactt
    45721 gccagactct gctatcgatc tcttggatga ggcggcagca acagtgcaaa ataaatcaaa
    45781 gcatgtaaaa gcagacgatt ctgacttgag tccagctgac aaggccttga tggatggcaa
    45841 gtggaaacag gcagcccagc taatcgcaaa agaagaggaa gtgcctgtct ataaagactt
    45901 ggtgacagag tctgatattt tgaccacctt gagtcgcttg tcaggtatcc ccgttcaaaa
    45961 actgactcag actgatgcca agaaatactt aaacttggaa gctgaactgc acaaacgtgt
    46021 catcggtcaa gaccaagctg tttcaagtat tagtcgtgcc attcgccgca atcagtcagg
    46081 aattcgcagt cacaagcgtc cgatcggttc ctttatgttc ctaggaccca caggtgtcgg
    46141 taagaccgag ttggccaagg ctttggcaga agttctcttt gatgacgaat cagcccttat
    46201 ccgctttgat atgagtgagt atatggagaa attcgcagcc agccgtctaa atggagctcc
    46261 tccaggctat gtgggttacg aagaaggtgg ggagttgaca gagaaggttc gcaataaacc
    46321 ctattccgtt ctcctctttg atgaggtaga gaaggcccat ccagatatct ttaatgttct
    46381 cttgcaggtt ctggatgacg gtgtcttgac agatagcaag ggacgcaagg tcgatttttc
    46441 aaataccatt atcattatga catcgaactt aggtgcgact gcccttcgtg atgataagac
    46501 tgttggtttt ggggctaagg atattcgttt tgaccaggaa aatatggaaa aacgcatgtt
    46561 tgaagaactg aaaaaagctt atagaccgga attcatcaac cgtattgatg agaaggtggt
    46621 cttccatagc ctatctagtg accatatgca ggaagtggtg aagattatgg tcaagccttt
    46681 agtggcaagt ttggctgaaa aaggcattga cttgaaatta caagcttcag ctctgaaatt
    46741 gttagcaaat caaggatatg acccagagat gggagctcgc ccacttcgca gaaccctgca
    46801 aacagaagtg gaggacaagt tggcagaact tcttctcaag ggagatttag tggcaggcag
    46861 cacacttaag attggtgtca aagcaggcca gttaaaattt gatattgcat aaaagaataa
    46921 aagtaccagc atctgaccat aagtcacagt ggagtgaaac tcaatgaaaa tcaaagagca
    46981 aactaggcag ctagccgcag gttgctcaaa acactgtttt gaggttgcag atagagctga
    47041 cgtggtttga agagattttt gaagagtata agctgcaaga tgaatgattt tcttgtattg
    47101 acgttgttgt tgacaaaaag tagcggataa atgaaatcca ttccattatc atagatgata
    47161 ggctggtagg aaattttcaa atagcataca gaaaatagat gtatggagtt ctggtagtag
    47221 aaagggagag agatgaacat tttagttgca gatgacgagg aaatgattag agaaggaatt
    47281 gcagcatttc tgacagaaga gggttatcat gtcattatgg ctaaggatgg acaagaggtc
    47341 ttggaaaaat ttcaagatct ccctatccat ctcatggtac tggatttaat gatgcctagg
    47401 aagagtggtt ttgaagtgtt aaaagaaatc aatcaaaagc acgatattcc tgtcatcgtc
    47461 ttgagtgctc tgggagatga aactactcag tcacaggtat ttgatctcta tgctgatgat
    47521 catgtgacaa aacctttttc tttggtactg cttgtcaagc gtattaaggc gcttatcaga
    47581 cgttactacg tcatagagga tctttggcga tatcaggatg taacagtgga ttttacctct
    47641 tacaaagcac attataaaaa tgaagaaatt gatctcaaac caaaggaatt actggtacta
    47701 aagtgtttga ttcagcataa aaatcaagtt ttaagtagag agcagatatt ggaagaaatt
    47761 tcaaaagatg tagctgattt accttgtgat agggtcgttg atgtctatat tcgtactctt
    47821 cgcaaaaaat tagctttaga ttgtatcgtg actgtgaaaa atgttgggta taagattagc
    47881 ttatgataaa aaatcctaaa ttattaacca agtctttttt aagaagtttt gcaattctag
    47941 gtggtgttgg tctagtcatt catatagcta tttatttgac ctttcctttt tattatattc
    48001 aactggaggg ggaaaagttt aatgagagcg caagagtgtt tacggagtat ttaaagacta
    48061 agacatctga tgaaattcca agcttactcc agtcttattc aaagtccttg accatatctg
    48121 ctcaccttaa aagagatatt gtagataagc ggctccctct tgtgcatgac ttggatatta
    48181 aagatggaaa gctatcaaat tatatcgtga tgttagatat gtctgttagt acagcagatg
    48241 gtaaacaggt aaccgtgcaa tttgttcacg gggtggatgt ctacaaagaa gcaaagaata
    48301 ttttgctttt gtatctccca tatacatttt tggttacaat tgctttttcc tttgtttttt
    48361 cttattttta tactaaacgc ttgctcaatc ctctttttta catttcagaa gtgactagta
    48421 aaatgcaaga tttggatgac aatattcgtt ttgatgaaag taggaaagat gaagttggtg
    48481 aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg aaggttattc
    48541 atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag gtttcctttg
    48601 tccgtggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt atcctagaga
    48661 atatgcagca taatattgga gattacaaag atcatccaaa atatattgca aagagtataa
    48721 ataagattga ccagatgagc cgcttattgg aagaagtact ggagtcttct aaattccaag
    48781 agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat attttatcac
    48841 gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg acagatgcta
    48901 ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacctg attagtaatg
    48961 caattaaata ttcagataaa aatgggcgcg taatcatatc cgagcaagat ggctatctct
    49021 ctatcaaaaa tacatgtgcg cctctaagtg atcaagaact agaacattta tttgatatat
    49081 tctatcattc tcaaatcgtg acagataagg atgaaagttc tggtttgggt ctttacattg
    49141 tgaataatat tttagaaagc tatcaaatgg actatagttt tctcccttat gaacacggta
    49201 tggaatttaa gattagcttg tagacagatt agttttttat taaagttcat atagggttaa
    49261 cataagtgtg ttattctttg tgtagataaa agaaaggata ctaatatggt attagcgatt
    49321 attttagtaa cattctttat tcgattgatt tttttaaagc gttcgataga gaatgagaaa
    49381 cgaatcctta gcaatggcgg gaaagaattt ggagttgaga atacaaaacg attaactatg
    49441 gctcatattg ttttttatct ctcttgcttg gttgaggcaa tggtgcacaa gacaattttt
    49501 gatggcatgg gcatggttgg tttggtcttg cttatttttt ctatgctgat gttgatgttg
    49561 gtgattcact tgttgggaga tatttggaca gtgaagctta tgcttgtcaa taatcacaaa
    49621 tatgtagatc atatcttgtt taggacagta aaacacccta attacttttt aaatatttta
    49681 cctgagttga ttggcttgac cttgttgagt catgcttatg tgacttttgt tttagttttt
    49741 ccagtttatg cagttatttt gtatcgacga atagctgaag aggaaaagct attacatgaa
    49801 gttataatcc caaatggaag cataaagaga taaatacaaa attcgattta tatacagttc
    49861 atattgaagt gatatagtaa ggttaaagaa aaaatataga aggaaataaa catgtttgca
    49921 tcaaaaagcg aaagaaaagt acattattca attcgtaaat ttagtattgg agtagctagt
    49981 gtagtagttg ctagcttgtt cttaggagga gtagtccatg cagaaggggt tagaagtgag
    50041 aataacccca cggttacatc tagtgggcaa gatatatcga agaagtatgc tgatgaagtc
    50101 aagtcacatc tagaaaaaat attgagtgag atccaaacaa atttagatag aagtaaacat
    50161 atcaaaactg taaatctaat taacaaattg caagacatta agagaacgta tttgtatgaa
    50221 ttaaatgttt tagaagataa gtcgaaagct gagttgccgt caaaaataaa agcagagtta
    50281 gacgcagctt ttgagcagtt taaaaaagat acattaccaa cagaaccagg aaaaaaggta
    50341 gcagaagcta agaagaaggt tgaagaagct gagaaaaaag ccaaggctca aaaagaagaa
    50401 gattaccgta actacccaac cattacttac aaaacgcttg aacttgaaat tgctgagtcc
    50461 gatgtgaaag ttaaagaagc ggagcttgaa ctagtaaaaa aggaagctga cgaatctcga
    50521 aacgagggca caattaacca agcaaaagcg aaagttgaga gtgaacaagc tgaggctaca
    50581 aggttaaaaa aaatcaagac agatcgtgaa aaagcagaag aagaagctaa acgaagagca
    50641 gatgctaaag agcaagatga atcaaagagg cgaaagagtc gggtaaaacg aggagatctt
    50701 ggagagccag caacacctga taaaaaagaa aatgatgcga agtcttcaga ttctagcgta
    50761 ggtgaagaaa ctcttccaag cccatccctg aaaccaggaa aaaaggtagc agaagctgag
    50821 aagaaggttg aagaagctga gaaaaaagcc aaggatcaaa aagaagaaga tcaccgtaac
    50881 tacccaacca ttacttacaa aacgcttgaa cttgaaattg ctgagtccga tgtggaagtt
    50941 aaaaaagcgg agcttgaact agtaaaagag gaagctaagg gatctcgaaa cgaggaaaaa
    51001 gttaagcaag caaaagcgga agttgagagt aaaaaagctg aggctacaag gttagaaaaa
    51061 atcaagacag atcgtaaaaa agcagaagaa gaagctaaac gaaaagcagc agaagaagat
    51121 aaagttaaag aaaaaccagc tgaacaacca caaccagcgc cggctcctca accagaaaaa
    51181 ccagctccag ctccaaaacc agagaatcca gctgaacaac caaaagcaga aaaaccagct
    51241 gatcaacaag ctgaagaaga ctatgctcgt agatcagaag aagaatataa tcgcttgact
    51301 caacagcaac cgccaaaaac tgaaaaacca gcacaaccat ctactccaaa aacaggctgg
    51361 aaacaagaaa acggtatgtg gtacttctac aatactgatg gttcaatggc gacaggatgg
    51421 ctccaataca atggttcatg gtactacctc aacgctaatg gtgatatggc gacaggatgg
    51481 ttccaataca atggttcatg gtactacctc aacgctaatg gtgatatggc gacaggatgg
    51541 ctccaataca atggttcatg gtactaccta aacagcaatg gtgctatggt aacaggatgg
    51601 ctccaataca atggttcatg gtactacctc aacgctaacg gttcaatggc aacagattgg
    51661 gtgaaagatg gagatacctg gtactatctt gaagcatcag gtgctatgaa agcaagccaa
    51721 tggttcaaag tatcagataa atggtactat gtcaatggct caggtgccct tgcagtcaac
    51781 acaactgtag atagctatag agtcaatgcc aatggtgaat gggtaaacta aacctaatat
    51841 aactcgttaa tgctggcttc ctgtaagaac tctttaaagt attccctaca aataccatat
    51901 cctttcagta gataatatac ccttgtagga agtttagatt aaaaaataac tctgtaatct
    51961 ctagccggat ttatagcgct agagactacg gagttt
//
LOCUS       DAVLAQ010000009        43340 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000009 DAVLAQ010000000
VERSION     DAVLAQ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.009"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            80..1555
                     /locus_tag="VXB71_000499"
     CDS             80..1555
                     /locus_tag="VXB71_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0450664.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1905..8606
                     /locus_tag="VXB71_000500"
     CDS             1905..8606
                     /locus_tag="VXB71_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0450665.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8854..9710)
                     /locus_tag="VXB71_000501"
                     /pseudo
     CDS             complement(8854..9710)
                     /locus_tag="VXB71_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9921..10280)
                     /locus_tag="VXB71_000502"
     CDS             complement(9921..10280)
                     /locus_tag="VXB71_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0450666.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            10372..11328
                     /locus_tag="VXB71_000503"
                     /pseudo
     CDS             10372..11328
                     /locus_tag="VXB71_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11312..11869
                     /locus_tag="VXB71_000504"
     CDS             11312..11869
                     /locus_tag="VXB71_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0450667.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11862..12116
                     /locus_tag="VXB71_000505"
     CDS             11862..12116
                     /locus_tag="VXB71_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450668.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12128..14182
                     /locus_tag="VXB71_000506"
     CDS             12128..14182
                     /locus_tag="VXB71_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0450669.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14361..15221
                     /locus_tag="VXB71_000507"
     CDS             14361..15221
                     /locus_tag="VXB71_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0450670.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            15432..16142
                     /gene="ccdA2"
                     /locus_tag="VXB71_000508"
     CDS             15432..16142
                     /gene="ccdA2"
                     /locus_tag="VXB71_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0450671.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16162..16728
                     /locus_tag="VXB71_000509"
     CDS             16162..16728
                     /locus_tag="VXB71_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0450672.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SVAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16739..17851
                     /gene="msrB"
                     /locus_tag="VXB71_000510"
     CDS             16739..17851
                     /gene="msrB"
                     /locus_tag="VXB71_000510"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0450673.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18119..18856
                     /locus_tag="VXB71_000511"
     CDS             18119..18856
                     /locus_tag="VXB71_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450674.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            18853..20544
                     /locus_tag="VXB71_000512"
     CDS             18853..20544
                     /locus_tag="VXB71_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0450675.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            20660..21223
                     /locus_tag="VXB71_000513"
     CDS             20660..21223
                     /locus_tag="VXB71_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0450676.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            21245..26914
                     /locus_tag="VXB71_000514"
     CDS             21245..26914
                     /locus_tag="VXB71_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0450677.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEALKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            26975..28696
                     /gene="pabB"
                     /locus_tag="VXB71_000515"
     CDS             26975..28696
                     /gene="pabB"
                     /locus_tag="VXB71_000515"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0450678.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            28816..30342
                     /locus_tag="VXB71_000516"
     CDS             28816..30342
                     /locus_tag="VXB71_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0450679.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            30429..31348
                     /locus_tag="VXB71_000517"
                     /pseudo
     CDS             30429..31348
                     /locus_tag="VXB71_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            31483..32442
                     /locus_tag="VXB71_000518"
     CDS             31483..32442
                     /locus_tag="VXB71_000518"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0450680.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            32539..33378
                     /locus_tag="VXB71_000519"
     CDS             32539..33378
                     /locus_tag="VXB71_000519"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0450681.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(33426..33596)
                     /locus_tag="VXB71_000520"
     CDS             complement(33426..33596)
                     /locus_tag="VXB71_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0450682.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33717..34601
                     /gene="miaA"
                     /locus_tag="VXB71_000521"
     CDS             33717..34601
                     /gene="miaA"
                     /locus_tag="VXB71_000521"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0450683.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            34594..35832
                     /gene="hflX"
                     /locus_tag="VXB71_000522"
     CDS             34594..35832
                     /gene="hflX"
                     /locus_tag="VXB71_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0450684.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            35825..36448
                     /locus_tag="VXB71_000523"
     CDS             35825..36448
                     /locus_tag="VXB71_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0450685.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            36463..37392
                     /locus_tag="VXB71_000524"
     CDS             36463..37392
                     /locus_tag="VXB71_000524"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0450686.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            37413..38168
                     /locus_tag="VXB71_000525"
     CDS             37413..38168
                     /locus_tag="VXB71_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0450687.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(38222..39130)
                     /locus_tag="VXB71_000526"
     CDS             complement(38222..39130)
                     /locus_tag="VXB71_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0450688.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            39194..39463
                     /locus_tag="VXB71_000527"
     CDS             39194..39463
                     /locus_tag="VXB71_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0450689.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39463..39843
                     /locus_tag="VXB71_000528"
     CDS             39463..39843
                     /locus_tag="VXB71_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0450690.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            39932..40159
                     /locus_tag="VXB71_000529"
                     /pseudo
     CDS             39932..40159
                     /locus_tag="VXB71_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(40199..40924)
                     /locus_tag="VXB71_000530"
     CDS             complement(40199..40924)
                     /locus_tag="VXB71_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0450691.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            41086..42927
                     /gene="typA"
                     /locus_tag="VXB71_000531"
     CDS             41086..42927
                     /gene="typA"
                     /locus_tag="VXB71_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0450692.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42947..43201
                     /locus_tag="VXB71_000532"
     CDS             42947..43201
                     /locus_tag="VXB71_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0450693.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
BASE COUNT        13391 a         7924 c         9587 g        12438 t
ORIGIN      
        1 aagcagctat taaagaacat ggattaagct aattctaatt tgttaacatt catataacat
       61 aaaaaaggga ggaactgtta tggatgcaat ctttgaccta atcggaaagg ttttcaatcc
      121 catcttagaa atgggtggac ctgtcatcat gttgatcatt ttgacagtat tggctttact
      181 ttttggagtg aaattctcca aagcgcttga aggtggtatc aaacttgcca tcgctcttac
      241 aggtatcggt gctatcatcg gtatgctaaa tggtgctttc tcagcatcac ttgcaaaatt
      301 cgttgaaaac actggtatcc aattgagtat tacagacgtt ggttgggcac cactcgcaac
      361 aatcacttgg ggttctgctt ggacactata cttcttgctc atcatgttga ttgtcaacgt
      421 agtgatgctt gctatgaaga aaaccgatac acttgatgtc gatatctttg atatctggca
      481 cttgtctatc acaggtctct tgattaaatg gtatgctgat aacaatggtg tgagtcaagg
      541 ggtttcactc tttattgcta cagcagctat cgtccttgtc ggtgtgttga aaattatcaa
      601 ctctgacttg atgaaaccta catttgatga ccttcttaac gccccaagtt catcaccaat
      661 gacatcaact cacatgaact acatgatgaa cccagttatc atggttttgg ataagatttt
      721 tgaaaaattc ttcccaggcc ttgataaata tgactttgat gctgctaaat tgaacaagaa
      781 aatcggtttc tggggatcta aattcttcat cggtttcatc cttggtatcg ttatcggtat
      841 tatgggaact ccacatccaa ttgcaggtgt tgcagatgca gataaatggc gtcttgttat
      901 caaaggatgg ttgtctcttg gtttgactgc cggtgtatct ttggaactct tctcacttat
      961 cggttcatgg ttcatcgcag ccgtagaacc actatcacaa ggtattacaa acgttgctac
     1021 taaacgtctt cgaggacgta aattcaatat cggtcttgac tggccattca tcgctggtcg
     1081 tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc atgttgattg aagcagtgct
     1141 tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt atcatcgcta tgggtgttac
     1201 tccagctctc ttggttgtaa ctcgtggtaa attgctccgt atgattatct tcggaacact
     1261 cttgttgcca ctcttccttc tttcaggtac acttattgca ccatttgcaa cagaacttgc
     1321 taaaggtgta ggtgccttcc cagaaggtgt gagccaaact caattgatta ctcactctac
     1381 tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt ggtaacacta caactggtga
     1441 tatcaaagca atccttggtg cagtagtctt ccttgtattc tatatcggta tctttgcttg
     1501 gtacagaaaa caaatgatca aacgtaacga agagtacgca gcaaaagcaa aataatgcgc
     1561 tcctataaaa tataaactca atgaaaatca aagagcaaac taggaaacta gccgcaggtt
     1621 gctaaaaaca cagttttgag gttgtagata agactgacga agtcagctca aaacatggtt
     1681 ttgaggttgt agatgaaact gacgaagtca gctcaaaaca tggttttgag gttgtagatg
     1741 aaactgacga agtcagtaat catatctacg gcaaggcgac gctgacgaag tttgaattgg
     1801 attttcgcag agtgtaaatt gttgaaacta ggttgtcata ccatgtatac cacttgggct
     1861 ttggtagtag ctaactgcac taaatataat ataaggaggg ttttatgggg aaaggccatt
     1921 ggaatcggaa aagagtttat agcattcgta agtttgctgt gggagcttgc tcagtaatga
     1981 ttgggacttg tgcagttcta ttaggaggaa atatagctgg agaatctgta gtttatgcgg
     2041 atgaaacact tattactcat actgctgaga aacctaaaga ggaaaaaatg atagtagaag
     2101 aaaaggctga taaagctttg gaaactaaaa atgtagttga aaggacagaa caaagtgaac
     2161 ctagttcaac tgaggctatt gcatctgaga agaaagaaga tgaagccgta actccaaaag
     2221 aggaaaaagt gtctgctaaa ccggaagaaa aagctccaag gatagaatca caagcttcaa
     2281 gtcaagaaaa accgctcaag gaagatgcta aagctgtaac aaatgaagaa atgaatcaaa
     2341 tgattgaaga caggaaagtg gattttaatc aaaattggca ctttaaactc aatgcaaatt
     2401 ctaaggaagc cattaaacct gatgcagacg tatctacgtg gaaaaaatta gatttaccgt
     2461 atgactggag tatctttaac aatttcgatc atgaatctcc tgcacaaaat gaaggtggac
     2521 aactcaacgg tggggaagct tggtatcgca agactttcaa actagatgaa aaagacctca
     2581 agaaaaatgt tcgccttact tttgatggcg tctacatgga ttctcaagtt tatgtcaatg
     2641 gtcagttagt ggggcattat ccaaatggtt ataaccagtt ctcatatgat atcaccaaat
     2701 accttcacaa agatggtcgt gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa
     2761 gtagccgttg gtattcagga agtggtatct atcgtgatgt gactttacaa gtgacagata
     2821 aggtgcatgt tgagaaaaat gggacaacta ttttaacacc aaaacttgaa gaacaacaac
     2881 atggcaaggt tgaaactcat gtgaccagca aaatcgtcaa tacggacgac aaagaccatg
     2941 aacttgtagc cgaatatcaa atcgttgaac gaggtggtca tgctgtaaca ggcttagttc
     3001 gtacagcgag tcgtacctta aaagcacatg aatcaacaag cctagatgcg attttagaag
     3061 ttgaaagacc aaaactctgg accgttttaa atgacaaacc tgccttgtac gaattgatta
     3121 cgcgtgttta ccgtgacggt caattggttg atgctaagaa ggatttgttt ggttaccgtt
     3181 actatcactg gactccaaat gaaggtttct ctttgaatgg tgaacgtatt aaattccatg
     3241 gagtatcctt gcaccacgac catggggcgc ttggagcaga agaaaactat aaagcagaat
     3301 atcgccgtct caaacaaatg aaggagatgg gagttaactc tatccgtaca acccacaacc
     3361 ctgctagtga gcaaaccttg caaatcgcag cagaactagg tttactcgtt caggaagagg
     3421 cctttgatac gtggtatggt ggcaagaaac cttatgacta tggacgtttc tttgaaaaag
     3481 atgccactca cccagaagct cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca
     3541 tggtcgaaag aggcaaaaac aaccctgcta tcttcatgtg gtcaattggt aatgaaatag
     3601 gtgaagctaa tggtgatgcc cactctttag caactgttaa acgtttggtc aaggttatca
     3661 aggatgttga taagactcgc tatgttacca tgggagcaga taaattccgt ttcggcaatg
     3721 gtagcggagg gcatgagaaa attgctgatg aactcgatgc tgttggattt aactattctg
     3781 aagataatta caaagccctt agagctaagc atccaaaatg gttgatttac ggttcagaaa
     3841 catcatcagc aacccgtaca cgaggaagtt actatcgccc tgaacgtgaa ttgaaacata
     3901 gcaatggacc tgagcgtaat tatgaacagt cagattatgg aaatgatcgt gtgggttggg
     3961 ggaaaacagc aaccgcttca tggacttttg accgtgacaa cgctggctat gctggacagt
     4021 ttatctggac aggtacggac tatattggtg aacctacacc atggcacaac caaaatcaaa
     4081 ctcctgttaa gagctcttac tttggtatcg tagatacagc cggcattcca aaacatgact
     4141 tctatctcta ccaaagccaa tgggtttctg ttaagaagaa accgatggta caccttcttc
     4201 ctcactggaa ctgggaaaac aaagaattag catccaaagt agctgactca gaaggtaaga
     4261 ttccagttcg tgcttattcg aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc
     4321 ttggtcttaa gactttcaat aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg
     4381 caaatgctaa tgaactttat cttgaatgga aagttgccta tcaaccaggt accttggaag
     4441 caattgctcg tgatgaatct ggcaaggaaa ttgctcgaga taagattacg actgctggta
     4501 agccagcggc agttcgtctt attaaggaag accatgcgat tgcagcagat ggaaaagact
     4561 tgacttacat ctactatgaa attgttgaca gccaggggaa tgtggttcca actgctaata
     4621 atctggttcg cttccaattg catggccaag gtcaactggt cggtgtagat aacggagaac
     4681 aagccagccg tgaacgctat aaggcgcaag cagatggttc ttggattcgt aaagcattta
     4741 atggtaaagg tgttgccatt gtcaaatcaa ctgaacaagc agggaaattc acccttactg
     4801 ctcactctga tctcttgaaa tctagtcaag tcactgtctt tactggtaag aaagaaggac
     4861 aagaaaagac tgttttgggg acagaggtgc caaaagtaca gaccattatt ggagaggcac
     4921 ctgaaatgcc taccactgtt ccgtttctat acagtgatgg tagtcgtgca gaacgtcctg
     4981 taacctggtc ttcagtagat gtgagcaagc ctggtattgt aacggtgaaa ggtatggctg
     5041 acggacgaga agtagaagct cgtgtagaag tgattgctct taaatcagag ctaccagttg
     5101 tgaaacgtat tgctccaaat actgacttga attctgtaga caaatctgtt tcctatgttt
     5161 tgactgatgg aagtgtacaa gagtacgaag tagatagctg ggagattacg gaagtagata
     5221 aagccaaact ttcagtagct ggatcacgta ttcaaatgac tggtcagtta gctggagaaa
     5281 ctattcatgc aacccttgtg gtagaagaag gaaatgctgc agcacctgta gtgccaactg
     5341 ttactgttgg aggtgaagca gtaacaggtc ttactagtcg acaaccaatg caatatcgta
     5401 ctctatctta tggtgcccaa ttgccagaag tcacagcaag tgctgaaaat gctgatgtga
     5461 cagttcttca agcaagcgca gcaaacggca tgcgtgcaag catatttgtt cagcctaaag
     5521 atggtggccc tcttcaaacc tatgcaattc aattcctaga agaagcacca aaaattgctc
     5581 acttgagctt gcaagtggaa aaagctgaca gtctcaaaga agaccaaact gtcaaattgt
     5641 cggttcgagc tcactatcaa gatggaacgc aagctgtatt accagctgat aaagtaacct
     5701 tctctacaag tggtgaaggg gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc
     5761 caggagcagt cactctcaaa gcggaatatg agggagctaa aggccaagtt gaactcacta
     5821 tccaagccaa tactgagaag aagattgcgc aatctatccg tcctgtaaat gtagtcacag
     5881 atttgcatca aaaacctact cttccaacaa cagtaacggt tgagtatgac aaaggtttcc
     5941 ctaaagctca caaagtcact tggcaagcta ttccgaaaga aaaactagac tcctatcaaa
     6001 catttgaagt actaggtaaa gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg
     6061 tagaaggtat cgtttcagtt gaagaagtca gtgtgacaac tccaatcgca gaagcaccac
     6121 aattaccaga aagtgttcgg acatatgatt caaatggtca cgtttcatca gctaaggttg
     6181 catgggatgc gattcgtcca gagcaatacg ctaaggaagg tgtctttaca gttaatggtc
     6241 gcttagaagg tactcaatta acaactaaac ttcatgttcg cgtatctgct caaactgagc
     6301 aaggtgcaaa catttctgac caatggaccg gttcagaatt gccacttgcc tttgcttcag
     6361 actcaaatcc aagcgaccca gtttcaaatg ttaatgacaa gctcatttcc tacaataacc
     6421 aaccagccaa tcgttggaca aactggaatc gtactaatcc agaagcttca gtcggtgtcc
     6481 tattcggaga ttcaggtatt ttgagcaaac gttcagttga taacttaagc gttggcttcc
     6541 atgaagacca tggagttggt gcaccgaagt cttatgtgat tgagtattat gttggtaaga
     6601 ctgtcccaac agctcctaaa aaccctagtt ttgttggtaa tgaggaccat gtctttaatg
     6661 attctgccaa ctggaaacca gttactaatc taaaagcccc tgctcaactc aaggctggag
     6721 aaatgaacca ctttagcttt gataaagttg aaacctatgc tgttcgtatt cgcatggtga
     6781 gagcagacaa caaactagga acgtctatca cagaggtaca aatctttgcg aaacaagttg
     6841 cggcagccaa gcaaggacaa acaagaatcc aagttgacgg taaagactta gcaaacttca
     6901 accctgattt gacagactac taccttgagt ctgtagatgg aaaagttacg gcagtcacag
     6961 caagtgttag caacaatggc ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccgg
     7021 ttcgtgtcat cgcgaaagct gaaaatggcg acatcttagg agaataccgt ctgcacttca
     7081 ctaaggataa gaacttactt tctcataaac cagttgctgc ggttaaacaa gctcgcttgc
     7141 tacaagtagg tcaagcactt gaattgccga ctaaggttcc agtttacttc acaggtaaag
     7201 acggctacga aacaaaaaac ctgacagttg aatgggaaga agttccagcg gaaaatctga
     7261 taaaagcagg tcaatttacc gttcgaggcc atgtccttgg tagtgatctt gttgctgagg
     7321 tcactgtacg agtgacagac aaactaggcg aagctctttc agataaccct aactatgatg
     7381 aaaacagtaa ccaggccttt gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc
     7441 gcgttgacta tctcaatgac ggagatcatt cagaaaatcg tcgttggaca aactggtctc
     7501 caacaccatc ttctaatcca gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga
     7561 ttgtagaacg gactgttgct caagccaaac ttcacttctt tgcagatagt ggtacggatg
     7621 caccaactaa actcgtttta gaacgctatg tcggtccaga gtttgaagtg ccaacctact
     7681 attcaaacta ccaagcctac gacgcagacc atccattcaa caatccagaa aattgggaag
     7741 ctgtgcctta tcgtgcggat aaagacatcg cagctggtga tgaaatcaac gtaacattta
     7801 aagctgtcaa agccaaagct atgagatggc gtatggagcg taaagcagat aagagcggtg
     7861 ttgcgatgat tgagatgacc ttccttgcac caagtgaatt gcctcaagaa agcacgcaat
     7921 cgaagattct tgtagatgga aaagaacttg ctgatttcgc tgaaaatcgt caagactatc
     7981 aaattaccta taaaggtcaa cggccaaaag tctcagttga agaaaacaat caagtagctt
     8041 caactgtggt agatagtgga gaagatagcc ttccagtact tgttcgcctc gtttcagaaa
     8101 gtggaaaaca agtcaaggaa taccgtatcc agttgactaa ggaaaaacca gtttctgaga
     8161 agacagttgc tgctgtacaa gaagatcttc caaaactcga atttgttgaa aaagatttgg
     8221 cctacaagac agttgagaaa aaagattcaa cactgtatct aggtgaaact cgtgtagaac
     8281 aagaaggaaa aactggtaaa gaacgtatct ttacagcgat taatcctgat ggaagtaagg
     8341 aagaaaaact ccgtgaagtg gtagaagctc cgacagaccg catcgtcttg gttggaacca
     8401 aaccagtagc tcaagaagct aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa
     8461 ttgattcaag tgaagctagt caaactaata aagcccagtt accaaataca ggtagtgcgg
     8521 caagccaagc agcagtagca gcaggtttag ctcttctagg tttgagtgca ggattagtag
     8581 ttactaaagg taaaaaagaa gactagaaat tttgatacct tctttatcat taaagaccaa
     8641 agaaaaactc ttgtcctaaa tagaagataa agagtctgga acaaaatagt tctcaaccac
     8701 aaaaaagcta gatatttcca attgcggaac tctagctttt taattttgag tcgttctctt
     8761 attgtatagt agattgaaac tagagtagta cacttctact tctaaaacat tgttagaaat
     8821 cgatttgact gtccttatcg atttgtcctg ttcttatttc atttcactat gttttaggag
     8881 gttattggcc ataagtacca atcccatgtc aattctcact tgacgcttgc ctctcagatt
     8941 acatctcttg taacccaaac aagcctttat ctgcccaaag acaggttcta catcaatctt
     9001 gcgttgagcg aaaatctgtc tatcttgggg agataaaagc gcctgacatt ctttagcttt
     9061 caagttttga tagcgttcgt tcatatacaa tcccttttga ggggctgatt caggttcatc
     9121 agcgtagtaa accttgattt cctgttgaaa gtctgtctgt gttttctggt acttgatatg
     9181 gtgaaaacga tagcaccagc catcaggatg tatgtagcta tcctccttgt cattatagtg
     9241 ccaattcgct aagtttttag ctgactgttt ataccctctc ttttgttcct tatcaaacat
     9301 ggcatattta atcagaaggg gagtgatttc ttcttgaaaa tagacttgta tctgttcttg
     9361 aagtttggcg gagaatttct ctgtcgtttt cttccacaca aaactatact tgttggcatt
     9421 ggattcaatc ttagttccgt caataaacaa acaatctaag gtcactaact cttccatttt
     9481 tcaatttttc gaccagagaa aatcccttgt gaataggcaa atagaagagt agatacaagc
     9541 attttagggt gataagacgg gcgaccaaag gcatgatagg aggtgtagaa gtgacgttcc
     9601 tccaaggtat tcaccacttt ttcaatagta aagacgagat ggtcttgtgg taagaaggaa
     9661 ctgatttcta gtggtaaagt tgtttgattt gtgttatagt gaatatgcat gggatagcct
     9721 ttctaaatgg tttattaagc aattctattt taccaagact atcgtaacca tgcaaaaaag
     9781 caacggcaaa tccgttgcct tttttggata taagagacta ttgtcccaga ctcttttctt
     9841 tgtataaaat tgtatagtgt tattgtctat actattttgt agagaaagca aaaatcccta
     9901 gaaaatgctt agggattcga ctatttcatt aagaacaatt caacaatcat ctctatatac
     9961 atgataaggg ttaataaaaa tcctgtacgc cagaagaatt tgatgaattt aggatagtaa
    10021 aagctgcgtt tttttaaaag gaagaaaaag acgagaataa tggctaggaa cgagagggct
    10081 agccccagtc tagggaggaa attatgggta aaggttttag ctgtaatcaa gtaatactca
    10141 aataccaaga ctggaaaagc caaatccgca aagtttcgtc ctagtttttt taatctaaaa
    10201 agtttggtta ggataatgca gacgactaag gtcagtatca ataataaaat agatgctaat
    10261 ttcattaaaa tcatacccat attgtatcat aaaaaaaggc taatggaaac gagaaacaga
    10321 ggaatttata ggaaagtcag gcttttgaga ttgtgggtga tttttgttat aatgaaagtt
    10381 ataaaatctt atgatacctt gaatgattat tatcgaaaac tctttggaga aaagactttt
    10441 aaagtcccta ttgatgcggg atttgactgt cccaatcgtg atggaactgt ggctcatgga
    10501 ggctgtactt tttgtacggt ttccggttct ggagatgcca ttgtagcccc agatccgcct
    10561 atccgtgagc aattttataa ggaaattgac tttattcatc gtaagtggcc agatgttcag
    10621 aagtatctgg tttattttca aaattttacc aacacccatg aaaaggtgga agttattcga
    10681 gagcgttatg aacaggctat caatgagcca ggtgtggtag gaatcaatat tggaacgcgc
    10741 ccagactgtt taccagacga aaccatcgaa tatttggctg agttatcgga gtgcatgcat
    10801 gtgacggttg aattgggctt gcagactact tatgaagcaa cctctgacct gattaaccgt
    10861 gcgcattctt atgaattgta ggtggaaacg gtcaagcgtt tgagaaagta tccaaaaatt
    10921 gagattgttt cccatttgat caatggtttg cctggtgaaa cccatgagat gatggttgaa
    10981 aatgtccgcc gttgtgtcac ggataacgat attcaaggga ttaaactgca tttgctccat
    11041 cttatgacaa atactcgtat gcaacgagat taccatgagg gacgtttaca attgatgagt
    11101 caggacgaat atgtcagggt catctgtgac caactggaaa ttattcccaa acatatcgtc
    11161 atccatcgaa ttacaggaga tgcgcctagg gatatgctga ttggtcctat gtggagcctc
    11221 aataaatggg aagtcctcaa cagcattgag atggagatga gacgtcgtgg aagtgttcaa
    11281 ggatgcaagg ctgtaaaaca ggagtttgaa aatgaaaaga ccacttgaga tggcacatga
    11341 ttttttggct gaggtcgtga caaaagagga tgtcgtagtg gatgcgacta tgggaaatgg
    11401 tcatgacacg ctttttttag ccaagctagc caagcaagtc tatgcctttg atattcagaa
    11461 gcaagccttg gaaaagaccc aagagcgttt gcatcaggct ggcttgacaa atgcccagtt
    11521 aatcttgcaa ggccatgaga cactggacca gtttgtgaca aaagctaagg cagggatttt
    11581 taatttgggc tatttgccgt cagctgataa gtctgtcatc acccgaccgc agacaacgat
    11641 tgaggcatta gaaaagctat gtggcttact tgtcaaaggt ggacgaattg ctattatgat
    11701 ttactatggt catgaaggag gcgacctcga gagagatgct gtcttggatt ttgtgatcca
    11761 gttgaaccaa caagagtaca cagctgccat ttaccgaact ttaaaccaag tcaacaaccc
    11821 gccgttttta gtgatgattg aaaaattaga gagatacaga catggataaa caatacctac
    11881 acgaaaagct ggatgccatg cgccagaatt ttgttgaatc aacctaccac gaacgagcgg
    11941 tgggcgtgct agaccaagcg catatgagca aaaaaatgct taaaatcaag aaaaaattag
    12001 ttgctcttga aatggaacgg tgccagagaa aaattgagca caaagactgt tccaagattg
    12061 accaaaaaat caaagagcag aaggagatat ttgaatcctg ttgtaaaaaa gattaaggag
    12121 gacgtgcgtg gaattactga tttacctcat cctattttta ctggtcttga ttgtctcaag
    12181 tacaaccaat aagctcctac cctttttgcc tctccctttg gtgcagattc ttttgggaat
    12241 tgtgattggt ctctttttac ccaatactga ctttcacctt aatacggagt tgtttttggc
    12301 actggttatc ggccccttgc ttttccgaga ggctgaagaa gcagatgtta cggctatttt
    12361 aaaacactgg cgaatcattg tttatctcat atttccagtg atttttatct cgaccctgag
    12421 tttgggtggc ttggcccatc ttctttggtt cagccttccc ttggcagctt gcttggctgt
    12481 tggggcagcc cttggtccta cggacttggt ggcctttgcc tctctttcgg agcgttttag
    12541 ctttcctaag cgcgtgtcca atattcttaa gggcgaagga ctcttgaatg atgcttctgg
    12601 tttggtggct tttcaggtag ctttgacagc ttggacaact ggagcttttt ctctggggca
    12661 agctagcagt tcactcatct tttcaatcct aggcggtttt ttaattggat ttttaacagc
    12721 catgaccaac cgcttcctcc ataccttctt gctaagtgtg cgtgcaacgg atattgccag
    12781 tgaactttta ttagaattga gtttgcctct tgtgaccttc tttctggcag aagaagttca
    12841 tgtttcaggt attattgccg tcgtagttgc tggaatttta aaggcaagtc gtttcaagaa
    12901 aatcacgctc ctcgaagccc aagtggatac ggtgaccgag acggtctggc atacagtgac
    12961 ctttatgctc aacggttctg tctttgtgat tttagggatg gagctggaaa tgatagcaga
    13021 acctatcttg accaatccaa tctataatcc tctactttta ttgctatctc ttatcgccct
    13081 tacctttgtc ctctttgtca ttcgttttat tatgatctat ggctattatg cctatagaac
    13141 ccgacgcctc aagaaaaagc taaataagta tatgaaggac atgtttctct tgaccttttc
    13201 aggtgttaag ggaacggtgt cgattgctac gattctcttg ataccaagta atctagaaca
    13261 ggagtatcct ctcttgcttt tccttgttgc aggtgtgacg cttgttagct ttttaacagg
    13321 tctcttggtc ttgcctcatc tttctgatga agaggaagaa agcaaggatt atctcatgca
    13381 tatcgccatt ttgaatgaag taacgctaga gttggaaaaa gagttggaag acaccagaaa
    13441 taaactttcc ctctatgcgg ctattgacaa ttatcatgga cgtattgaaa atctcatttt
    13501 aagccaagaa aaccaggatg atcaagaaga ctgggctgct ttgaaactct tgattcttag
    13561 tattgaaagt gatggtttgg aacaggccta tgaagagggg aatattagca atcgtgctta
    13621 ccgagtttac caacgttatc tgaaaaatat agaacaagga atcaatcgta aacttgcctc
    13681 aagactgacc tattattttc ttgtttcctt gaggatttta cgttttctcc ttcatgaagt
    13741 ttttactctt ggaaagacct tccgtagctg gaaggacaag gagcaaagcc gtctccgtgc
    13801 tcttgattat gaccaaattg cagagctcta tcttgccaat acagagatga ttattgaaag
    13861 tttggaaaac ctgaagggag tctacagacg ctctttgatt agttttatgc aggagtctcg
    13921 tcttcgagaa acagctatta tcagcagtgg tgcctttgtc gaacgggtta tcaatcgtgt
    13981 caaacccaac aatatcgatg aaatgctgag aggctattat ctggagcgca agttgatttt
    14041 cgaatacgaa gaaaaacgat taattacaac taagtatgcc aagaaattac gacaaaatgt
    14101 aaataactta gagaactatt ccttgaagga agctgccaat accctgccgt atgatatggt
    14161 ggaattggta agaagaaatt agttaatact cttcgaaaat ctcttcaaac cacgtcagcg
    14221 tcgccttgga ttatatatgt gactgacttc gtcagtttca tctacaacct caaagcaggg
    14281 ctttgagcaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagat
    14341 tataaatgaa ggagtatgac atgaaaaagt ggtggaaaga gctgatagac aagcctttat
    14401 taaaagcttt tttgcattat tatcaagcat cagatagtga gttgaccagt gtcgcagtag
    14461 cctactattg gttgatttcg attttccccc tgcttttggt ggtggtcaat atcctcccct
    14521 attttcagat tcctgtggga gaatttctgt gctttatgaa agacgttctg cccccaagcc
    14581 tctatgaagg tgtggaaaaa atagccagag aagttttgac gcaaccttca acaggtttat
    14641 tgagtttttc tgttttatcg gcgttatgga gtttttcaaa atctatgaat ttcttgcaaa
    14701 aagcttttaa caaggcttat ggcgtcgaaa agagtcgtgg acttatttcc catcagatgc
    14761 taagtctcct agtcagtttt ggcttgcagc tcctctttgc gtttgccttg tttttgatct
    14821 tatttggtca gatgattttg gctttacttg ctcattattg gacaaaagat ggcattatct
    14881 atcaggcttt acaagggttg gcaggtcctc tgatttacgc cctcctcttt gctatcttgg
    14941 tcatgcttta ttattttctt cccaatatat ctaacaggaa aattagctat accctaccag
    15001 gcagtgcctt tgttctctta gtgattttag gtttactaac tctgttctct agttatctca
    15061 attactatgt ccatcatttg gtggatgtcc gaattttagg ttccgttctt cttgttgtta
    15121 tgatgttttg gtttatcttg attgctaaaa ttgttatcct aggcgcggtt atcaatgcca
    15181 gtatgcagag tttgagagat ccggtcttta aaaaagacta actatttatc cattacaaaa
    15241 gcgcatagta tcaaaacttt atagaacctt gatactatgc gcttttgtgc tttgacagtt
    15301 ttttgtatag tttttgtcca agatttctaa atcatctgat taaattccta ttttccccta
    15361 tcattgtccc tgttttttcg aaaatggaag gagtataata aatctatcaa taaaatgata
    15421 ggaggaactt tatgggtcat attttctttt ttctaagtgt ctttttggca gggattctat
    15481 ccttcttttc tccttgtatc ttacctttgt taccggtcta tacaggagtg ttactagatg
    15541 ataaggatgg tgctcaggct tctagcggca aattttcaat ctcagttact agtttattac
    15601 gaactctggc ctttatagca ggaatttcct ttatatttat tttgttgggc tatggagctg
    15661 gttttttagg cgatttgctt tatgcttctt ggttccaata tcttactggg gcaattatta
    15721 tccttcttgg tttgcaccaa atggagattc tacactttaa ggggctttat aaggaaaaga
    15781 ggctacaact gcaaggacag gggcaaaatg gtaagggcta tagtcaggca tttttattgg
    15841 gcttgacctt tagttttgct tggacgcctt gcgtggggcc ggttctgggg tctgttttgg
    15901 ccttggcggc ttcaggtggt tcaggagctt ggcagggagc tggtctcatg ttggtgtata
    15961 cgctgggctt ggcgctacca ttcttgcttc tagctctgac ctctagttat gttttgaaac
    16021 atttccgaaa acttcatccc tatctcggaa tcctcaaaaa agtgggtggt tttctcatta
    16081 ttgtgatggg actcttggtt ctgtttggaa atgcttcaat tttaagtcaa ttatttgaat
    16141 aaaatggaaa ggaatatcaa tatgaaaaaa tggcaaacat gtgttcttgg agcaggttcg
    16201 ctcctttgtt tgacggcttg ttcaggcaag tccgtgacta gtgaacacca aacgaaagat
    16261 gaaatgaaga cggagcagac agctagtaaa acaagcgtag ctaaagggaa agaggtggct
    16321 gattttgaat tgatgggagt agatggcaag acctaccgtt tatctgatta caagggcaag
    16381 aaagtctatc tcaaattctg ggcttcttgg tgttccatct gtctggctag tcttccagat
    16441 acggatgaga ttgctaaaga agctggtgat gactatgtgg tcttgacagt agtgtcacca
    16501 ggacataagg gagagcaatc tgaagcggac tttaagaatt ggtataaggg attggattat
    16561 aaaaatctcc cagtcctagt tgacccatca ggcaaacttt tggaaactta tggtgtccgt
    16621 tcttacccaa cccaagcctt tatagacaaa gaaggcaagc tggtcaaaac acatccagga
    16681 ttcatggaaa aagatgcaat tttgcaaact ttgaaggaat tagcctagga ggtgtcttat
    16741 gaatgataag ttaaaaatct tcttgttgct aggagtattt tttctagcca taaccggttt
    16801 ctatgttcta ttgatacgaa atgcagggca gacagatgcc tcgcaaattg aaaaggcggc
    16861 agttagccaa ggaggaaaag cagtgaaaaa aacagaaatt agtgaagacg cagacttgca
    16921 cgaaatttat ctagctggag gttgtttctg gggagtggag gaatatttct cacgcgttcc
    16981 cggggtgacg gatgccgttt caggctatgc aaatggtaga ggagaaacaa ccaagtacga
    17041 attaattaac caaacaggtc atgcagaaac cgtccatgtc acctatgatg ccaagcaaat
    17101 ttctctcaag gaaatcctgc ttcactattt ccgcattatc aatccaacca gcaaaaataa
    17161 acaaggaaat gatgtgggga cccagtaccg tactggtgtt tattacacag atgacaagga
    17221 tttggaagtg attaaccaag tctttgatga ggtggctaag aaatacgatc aacctctagc
    17281 agttgaaaag gaaaacttga agaattttgt ggtggctgag gattaccatc aagactatct
    17341 caagaaaaat ccaaatggtt actgccatat caatgttaat caggcggcct atcctgtcat
    17401 tgatgccagc aaatatccaa aaccaagtga tgaggaattg aaaaagaccc tgtcacctga
    17461 ggagtatgca gttacccagg aaaatcaaac agaacgagct ttctcaaacc gttactggga
    17521 taaatttgaa tccggtatct atgtggatat agcaactggg gaacctctct tttcatcaaa
    17581 agacaaattt gagtctggtt gtggctggcc tagttttacc caacccatca gtccagatgt
    17641 tgtcacctac aaggaagata agtcctacaa tatgacgcgt atggaagtgc ggagccgagt
    17701 aggagattct caccttgggc atgtctttac ggatggtcca caggacaagg gcggcttacg
    17761 ttactgtatc aatagcctct ctatccgctt tattcccaaa gaccaaatgg aagaaaaagg
    17821 ctacgcttat ttactagatt atgttgatta atactcttcg aaaatctctt caaaccacgt
    17881 cagcgtcgcc ttaccgtatg tagggttact gacttcgtca gttttatcta caacctcaaa
    17941 gctatacttt gagctgactt cgtcagtttt atctacaacc tcaaagcggt actttgagaa
    18001 acctgtggct atcttcctag tttacttttt gatttttatt gagtataaga ggtctttcct
    18061 aagcagttag aggagaattt tgctatactg atactagtaa gtggtaaagg agcagagcat
    18121 gacctacaca atcttaatcg tagaagatga atatctggta agacaaggtt tgactaaact
    18181 ggtcaatgta gcagcctacg atatggaaat catcggtcag gctgaaaatg gaaggcaggc
    18241 ttgggaattg atccaaaagc aggtgccaga tatcatttta accgatatca acatgcctca
    18301 tctaaatggc atccagttgg ccagtctggt acgagaaacc tatcctcagg ttcatttggt
    18361 ctttttaaca ggttacgatg attttgatta tgccttgtct gctgtcaaac taggtgtgga
    18421 cgactacctg ctcaaaccct tttctcgtca ggatattgag gaaatgttgg ggaaaatcaa
    18481 acaaaaacta gacaaggaag agaaagaaga gcagttacaa gatttattga ctaataggtt
    18541 tgaaggaaac atggcccaga aaatccagtc tcatctggct gatagccaat ttagtttaaa
    18601 gtctttagcc agtgacttag gttttagtcc gacctatctg agttccttga ttaagaaaga
    18661 gttgggcttg ccttttcagg attatctggt gagagaacgt gttaaacaag ccaagctctt
    18721 gcttttaact acagatctga agatttatga gatcgcagag aaggttggtt ttgaagatat
    18781 gaactatttt acccaacgtt ttaagcagat tgcaggtgtg acacctcgtc agtttaagaa
    18841 gggagaagac cgatgaagcg ttcttctctt ttagttagaa tggttatttc catctttctg
    18901 gtctttctca ttctcctagc tctggttgga actttctact atcaatcaag ttcttcagcc
    18961 attgaggcca ccattgaggg caacagccaa acgaccatca gccagactag ccactttatt
    19021 cagtcttata tcaaaaaact agaaaccacc tcgactggtt tgacccagca gacggatgtt
    19081 ctggcctatg ctgagaatcc cagtcaagac aaggtcgagg gaatccgaga tttgtttttg
    19141 accatcttga agtcagataa ggacttgaaa actgttgtgc tggtgaccaa atctggtcag
    19201 gtcatttcta cagatgacag tgtgcagatg aaaacttcct ctgatatgat ggctgaggat
    19261 tggtaccaaa aggccattca tcagggagct atgcctgttt tgactccagc tcgtaaatca
    19321 gatagtcagt gggtcatttc tgtcactcaa gaacttgttg atgcaaaggg agccaatctt
    19381 ggtgtgcttc gtttggatat ttcttatgaa actctggaag cctatctcaa tcaactccag
    19441 ttggggcagc agggctttgc cttcattatc aatgaaaacc atgaatttgt ctaccatcct
    19501 caacacacag tttatagttc gtctagcaaa atggaggcta tgaaacccta catcgataca
    19561 ggtcagggtt atactcctgg tcacaaatcc tacgtcagtc aagagaagat tgcaggaact
    19621 gattggacgg tgcttggcgt gtcatcattg gaaaagttag accaggttcg gagtcagctc
    19681 ttgtggacct tgcttggggc cagtgtcaca tctcttcttg tctgtctctg cttagtgtgg
    19741 ttcagtctta aacgctggat tgctcctttg aaggatttga gagaaaccat gttggaaatt
    19801 gcttctggtg ctcaaaatct tcgtgccaag gaagttggtg cctatgaact gagagaagta
    19861 actcgccaat ttaatgctat gttggatcag attgatcagt tgatggtagc tattcgtagc
    19921 caggaagaaa cgacccgtca gtaccaactt caagcccttt cgagccagat taatccacat
    19981 ttcctctata acactttgga caccatcatc tggatggctg aatttcatga tagtcagcga
    20041 gtggtgcagg tgaccaagtc cttggcaacc tatttccgct tggcgctcaa tcaaggcaag
    20101 gacttgattt gtctctctga cgaaatcaat catgtccgcc agtatctctt tatccagaaa
    20161 caacgctatg gagataagct ggaatacgaa attaatgaaa atgttgcctt tgataattta
    20221 gtcttaccca agctggtcct acaacccctt gtagaaaatg ctctttacca tggcattaag
    20281 gaaaaggaag gtcagggcca tattaaactt tctgtccaga aacaggattc gggattggtc
    20341 atccgtattg aggatgatgg cgttggcttc caagatgctg gtgatagtag tcaaagtcaa
    20401 ctcaaacgtg ggggagttgg tcttcaaaat gtcgatcaac ggctcaaact tcattttgga
    20461 gccaattacc atatgaagat tgattctaga ccccaaaaag ggacgaaagt tgaaatatat
    20521 ataaatagaa tagaaactag ctaactccca gtcaattctg ggagttttat gcgtaattgg
    20581 gcaaactttc taggttgtct atcttgctaa aaacaagaaa aaacggtatg atagaagagt
    20641 gacaacagag gtaacagaga tgaacgagac acagattcaa agagaaacac gtcaggtagt
    20701 ggaagatgtt ttagaaaaga ccaatttgaa gcagggggcc ctttttgttt taggtctatc
    20761 ttctagtgag gtgctaggtg gtcatattgg gaaagaatcc agtcaagaga ttggtgagct
    20821 gatagtggag actatcttgg atattctagg tagtagaggt atccatttag cagttcaagg
    20881 ttgtgagcat gtcaatcggg ctctcgttgt tgaacgtcag gtggcagagc agtttggtct
    20941 ggaaattgtc agtgtccatc ctactcttca tgcaggaggt tcggggcagt tggcagcctt
    21001 taagtttatg caggatccag ttgaggttga atttatcaag gctcatgctg gattggatat
    21061 cggagacact gcaattggca tgcatgtcaa gcatgttcag gttccgattc gccctatttt
    21121 gagagagatt ggtcatgccc atgtaacggc actggctagt cgtccaaaat taatcggagg
    21181 tgcgcgtgcg cactatccgc aagatgctat tagaaagacc tgagaatgaa taaaggagat
    21241 aaaagtgttt aaaaaagacc gtttttcaat tcgtaagatt aagggagttg taggctctgt
    21301 atttcttgga agccttttga tggctccttc tgtagtggac gcagccacct atcactatgt
    21361 aaataaagag attatttcac aagaagctaa agatttaatt cagacaggaa agcctgacag
    21421 gaatgaagtt gtatatggtt tggtgtatca aaaagatcag ttgcctcaaa cagggacaga
    21481 agcatctgtt ttgacagctt ttggttatct atcaggtgac atcctcaaaa cgcttggctt
    21541 ggacactgtt ttagaagaaa cctcagcaaa acctggagag gtgactgtag tcgaagttga
    21601 gactcctcaa tcaacaacaa atcaggagca agctaggaca gaaaaccaag tagtagagac
    21661 agaggaagct ctaaaagaag aagcacctaa aacagaagaa agtccaaagg aagaaccaaa
    21721 atcggagata aaacctactg acgacaccct tcctaaagta gaagagggga aagaagattc
    21781 agcagaacca gctccagttg aagaagtagg tggagaagtt gagtcaaaac cagaggaaaa
    21841 agtagcagtt aagccagaaa gtcaaccatc agacaaacca acagaggaac caaaagttga
    21901 acaagtaggt gaaccagtcg agccaagtga agacgaacag gcaccaacgg caccagttga
    21961 gccagaaaag caaccagaag ctcctgaaga agagaaggct gtagaggaaa caccgaaacc
    22021 agaagataaa ataaagggta ttggtactaa agaaccagtt gataaaagtg agttaaataa
    22081 tcaaattgat aaagctagtt cagtttctcc tactgattat tctacagcaa gttacaatga
    22141 tcttggacct gttttagaaa ctgcaaaagg tgtctatgct tcagagcctg taaaacagcc
    22201 tgaggtaaat agtgagacaa ataaacttaa aacggctatt gacgctctaa acgttgataa
    22261 aactgaatta aacaatacga ttgcagatgc aaaaacaaag gtaaaagaac attacagtga
    22321 tagaagttgg caaaacctcc aaactggggt tacagaagct gaaaaagttg cagctaatac
    22381 agatgctaaa caaagtgaag taaattctga gactgcaagt cttaaaacag caatttctag
    22441 attaaataca gataaagttg aactcgaaaa tcaacttaag attgcacagg gaaaaactga
    22501 aactgatttc agcatggaat cttggactgt tttgagtaca gctaaaaata aagctcagga
    22561 agtaaaagat aacggaacag cgacccaaga acaaataaac gaagcagaga aaagtttgaa
    22621 aacagccctt gctgacttat ctgttgacaa aacagctttg ggaagcgcta tcgatacagc
    22681 tactaagaaa aataaagaga attatacaaa tcaaacatgg gcagagttgg aaacagcgct
    22741 tacagcagca aaatctgtaa atactaacga gtctaaacaa agcgacgtta acgaagctgc
    22801 tgaaaaatta actgcaacta tggaaaaatt ggttgaattg tctgaaaagc cacgtttgac
    22861 tctatctatt gaaaagagag acatagatcg aaaagctacg gtcacgtata ctttggaaaa
    22921 tccagcaaat actcaaataa aatcaataac tgcaactctg aaaaaaggag aggaagttgt
    22981 taaggatttt gttttaacag aagaaaatct taaaactaat catttaactg ctttgtttga
    23041 aaagctagac tactacaaag aatacactct atctacggat atggtatata acagaggaaa
    23101 tgatgatgag acggagagta tttcagaaga actaattcag ctgaatctta agaaactaga
    23161 attgaaagat atccagacag tctctctgat gaaatttgaa aatggtcaag aaagtcaggt
    23221 tacacacttg tctgataaac cgaccgattt gagtaaatta tacttaaaag ttacatcatc
    23281 aacgtctaag gatgctgtgt tagccgttag ctctatagaa gaagagatta ttgaaaataa
    23341 aaaaatcttt aaaattcatg cagatacacc agaattagta gttcgtaaga aagatggcag
    23401 tctttctaag ggatttgact attacatgga gagagttatc cctcatgatg gtgatattta
    23461 ttatgatttt aaagacttga tttcagctat gacatctaat cctacaggta cgtttatttt
    23521 agggagagat atttcctcgc gtaatgtaaa accggatgga aatggaaaat cttatatcaa
    23581 aggtgaattt aaaggaaaac tacttggtac aaatgataat gttagacact cgatctttga
    23641 cttagaatat ccattgtttg atactataaa atcaggagtc gtgaaagata ttgatttcaa
    23701 gcatgtcaat atggtattcc cagatagcaa tcaaggagat aacgtagcaa caattgcaag
    23761 agtaatcaaa gataagacaa aaattgagaa tgttaatgtt gaaggttatc tcgagggtcg
    23821 agatcatgta gctggtttag ttaataatct tgaaggtaat tccgaaattg aaaatgtatc
    23881 ctttacagga aagattaagt ctaaaggtgg taattctatt acagcaggta ttgcaggtag
    23941 aaatatctta tctcgtgtta aacgtgccta tgtaaatgca gatatagagg tacatcgatc
    24001 atctaattct agcatgcttg ttgcagtaaa tggaataaac gcagatgcaa gtggtggttg
    24061 gggaacctgg ggtagactta ctgagtcagt tgctaaagga acattagaaa ccaagcaagg
    24121 agggcaagct ggaggagcct cttctacagt ctggccttat ggagcaattg ataatgttgt
    24181 cagctatgca aaagtgacca aagggaaaga attatttgga tcagatggtg atttaaatta
    24241 tgattggttt atgaaaaaaa ttagtaatat ttttggtgtt caaggcatca gctcaggcga
    24301 ttcgggtagt gattctaaat ttacgcgtat ttctgaggaa gaagcaaatc aaaaagttgc
    24361 ttcttataat attacagctc ccaacttgat gagtgactca agtcttttgg tagacagact
    24421 caatgaaagt tggaaaaata ctgatcaatt tgaaagtata caggattatc aagcccaaaa
    24481 ccaattaatt taccagaact tgactaaatt tactccttat tacaataaag aatttattgt
    24541 tcatgaagga aatgctctca ctcctgaaca ggaaatattg aagactaaga aaatcaaatc
    24601 gattgtaggg ttgaaaggaa cagagttcgt tgtagatggc agtgatattg atactatcat
    24661 gcttcatttt gaggatggta gtcagaagcg atataaggta acctctactg gtaagttttc
    24721 gataactaat ttaccggaat atcaggttga agatttaaat gtggtgtata catcagaaca
    24781 tatagtacat ccactagatt cgtcactgat aaataacctt gttgaagaat tgaaaaaagt
    24841 agaattgtat acagagtcta cttaccaagt tctaggtatt gataaagata atgctaacaa
    24901 attgaataga actaagagat tattcttaga tgagtcatta gatgctgtta aaacacaatt
    24961 gcctaccttt gtaaaaacaa tgtttgaaaa tgagtggttg cacatcaatg gagaatctag
    25021 tggagctgtc gctgctttac gacaaaaaat catggataat aagacggcta tattgcttgc
    25081 tttgacttat atcaatcgtt attatgatgt taaattctca gactataata ttaaaaaact
    25141 gatgctcttt aaaccaactt tccatggtga aaagattgat ctattagatc gattaatccg
    25201 actaggatca tctggagaaa atagattaaa aggttcagaa aatgcagaaa cgttcaagca
    25261 gttatttgct agcgaaacga agcagaagga tttggtgact tatttagact acaatcgctc
    25321 tttgttgact aattatcaaa caacagggga atggtttaaa gaaacgacta aggattatat
    25381 tcaatttgag gaacgtccat ccttagtaga ggagattaaa gatgccaaat atcgagttta
    25441 cgataattta accgcaccgt attatcaagg atatatccta cctctcttaa cgttgaagaa
    25501 tactcattta gcaattttat cgaactatag tactatgaca tttgtcagcc gtgaaaaacg
    25561 ccctaattgg aaaaatgaag attttgataa gtgggtgaaa tatgtagcaa ctgctcatag
    25621 aaaccatgtt gatacttggt ataagatttt acctgataat atcaaaggta aaatggttaa
    25681 agagaatgtt actgctgttt gggaaggatt gagcatccca ggaagtgaat gggtagacca
    25741 gaatgctgta gatagaaaag gaagagatta cgccccagct cgagaattct ttaatcttgt
    25801 aggtggtcct atgggaggtt ggtatgctta ccatggttat ggtgcgcatg ctggaggaag
    25861 aaatcgggtt aattatgagg tgtttgatgt attaagtgag tatggtatat cggtctttac
    25921 tcatgaattg actcacgtta atgatacttg gatttactta ggagggtatg gtagacgtga
    25981 aaatatggga cctgaagctt atgctcaggg attattccag tctcctgttc caggtcagcc
    26041 gggttggggg gcgcttggtc tcaatatggc atttgaaaga aaaaatgatg gtgatctaat
    26101 ttataatgcc tccccaactc aatttgaaaa taggaaagag ttagatagtt atatgaaaaa
    26161 ttataacgat actctcatga tggtggacta cttggaagga gatgcagtta tctctaaagg
    26221 taaagaagct attactaaat ggtttaaaaa agttgaacct aaggttgtta gtcaaacagc
    26281 tcagtatgat acggttcgtc agttgactgc tgaagagaaa gaaaaacttt ctgtttctag
    26341 tgttgatgat ttagttgatc aaggattaat gtcagacaga gctgtaggaa ataataccta
    26401 taatccagct gattttgaaa caagttatat tgcgatagat tatatgactg gtatttatgg
    26461 tggaggaaag aatagtgtag gttcaccagg tgccttgatg tttaaacata atactttccg
    26521 tatgtggggc tactatggtt ttgaagaagg tgttctagga tatgcttcta ataaatttaa
    26581 gcaagcatct agagatgaag gtcatgctgg acttagtgat aactttatta tttctaagat
    26641 ttccaaaggg gaatttttaa ctatggaagc atttaaaaag ggatatttta agaaagtagt
    26701 agaagagtta aaaactaaag gtattcgtcc tgttactatc aatcaaaaaa catatagcac
    26761 ctttgaagaa ttgcaagaag gatttaagca ggctgttgaa agagatttga agaaaaatca
    26821 gttagatgag agggaaacaa gaaacttcaa attccaagtt ttcagacaac ttcttcaaca
    26881 aacagatagc tttaaaactt ctatctttag ataatcgaaa tctctcatct gctttgcgga
    26941 tgagggtttt cttattttat gctatactta aagtatgcat agaaaaacag tgattgattt
    27001 taggactttg ggggagagat atacctttac ccagcctatt aaagagttga aaacgagaaa
    27061 tgtagaagaa gtggcagatt tgctggcaca agtggaaagc taccaagagc aaggttatta
    27121 tgtggtgggg tatgtcagct acgaggctgc acctgctttt gaggaaaaat tagcagttca
    27181 caaggatccc ctactgggag agtacctgct ttattttact gttcatgata gcgtagaaac
    27241 ttcccctatt cctctgactt atgaggatat tgatttgccc tcaaattggc aggaagtaac
    27301 gtctgcagca gactatgaaa aggccattgc ccaaattcac catcatttac ggcagggaga
    27361 tacctatcag gtcaactaca ccgtccaact taagcaaaag ttaaatgcca atccttttgc
    27421 catctacaat cgtatggtgg tagagcagga ggcgggctac aatgcctatg tggaacatga
    27481 cgagatggca gtgatttcca tgagcccaga gctctttttt gagcaaaatg atcgcgagtt
    27541 gacaacacga ccaatgaagg ggacgactca gcgtggggta actgaccaag aagatcttga
    27601 acaggccagt tggttggaac aggatcccaa aaatcgctct gaaaatatga tgattgtgga
    27661 cctcttgcgc aatgatatga accgtatttc tgaagttggg agcgagcacg tggagcgtct
    27721 gtgtcaggta gagcagtatt caactgtttg gcagatgact tcgaccatca agagtcagtt
    27781 gcgagaggat gtggaccttg ttgaaatctt ccactcactc tttccttgtg gttccataac
    27841 gggtgcaccg aaaattgcga caatggagat tatcaaggac ttggagcctc aaccgcgtgg
    27901 agtctactgt ggaacgattg gtctcttgct tccaaatgga cgacggattt ttaatgtggc
    27961 cattcgtacc attcaacttc acaaaggtca agccatttat ggagttggcg gagggattac
    28021 ttgggatagc acttgggaat ctgaataccg tgaagttcat caaaaggcag cagttctcta
    28081 tcgtaaacaa gctcgcttcc aattaattac aactggaaaa atcagccaaa aacaactgat
    28141 gtttgaagaa caacatctgg aaaggctgag aaaagctagt cggtattttg cttatccttt
    28201 tgacccagaa attttgagac aaaagattga agcagagtgt cagacttgtg atgctaatca
    28261 agattaccgc ttgcgaattt ctctcagcaa gtctggagag atagaattca gtcgtcaaat
    28321 cttaacacct cttagtccaa gtttttgtca ggccaaactt tgtctgcaag aagcgaattt
    28381 gaatcaatcc tttacctatt ttaaaacgac ttacagaccg catttgagca tagaggaaca
    28441 agagaagatt taccataatg gaaaaggaga acttcttgaa acctctatcg gaaatttggt
    28501 tctgaaaatc gatgggaaac tctacacacc gcctatccga cttggaatct tgccaggaat
    28561 ttatcaccag tatttactag aaacaggaca ggtagaagag aaagtcttga ccttggcaga
    28621 ttttgcccaa gcagaagcta tttacggctg taatgcagtg agaggcttgt atgagttgca
    28681 agtgatagga ttgtgagttt tagctattaa tagtttttaa tatatattaa aatatattgg
    28741 tgtttacttt tgatgagata tcatatttgt gttataatgt aaccgtaaac aatagaaatt
    28801 taaaggagat ttttgatgaa atcaaaaata gttttgggag cttcgctagc gatcgcaaca
    28861 cttagcttag tatctcttgt cgagattgaa ggactctcac cgtttttaat agagaatgtt
    28921 agcgcaaata ctcattctgc aaataaagtt attaatcata aagtaagtat ttacttagaa
    28981 aatgctgatg aaggtaaagg tctaactgta aacttttcaa cagacagtgt tagtccaaat
    29041 ttatttgatg agttcgaaaa aaagagtgga attacaataa ctactatgtt agtgaatgct
    29101 aagacaggtg aagttgtaga aaaaagatta acaccaagcg tttttttacg ttccaatgat
    29161 ttaaccagtg ggaccatatc ttcgtttatt tttagtgaat atcctgatgg agaatataaa
    29221 tatgttgtgt ctaaaggaga ctttatcgat cctaagactc agtttaaaca tcagtataga
    29281 ggagaatctc cagtttttag aatacgtaat cgaaaatatg tggagttggg aacaactgat
    29341 aaaaaattag atgaaagacg tgataatagc gtttataaag atggggttgt tgaacacaag
    29401 gtaaatttaa gtttaacaag ttatcaagga ggtaatggag ttactgcaat tttttcaact
    29461 gatagtgtta actctaactt acttaattct tttggtgaaa aggctaaaaa agttttgatt
    29521 aggtctaagt taattaatgt taagactggc gaggttattg atgaaacgtt ttctccaaaa
    29581 gtaagtttaa cctctaaaat tttgaaaagt ggttctacag cagtatttta ttttatagat
    29641 ttaactgatg gcgaatataa atatgttgcg tatgaaagcc agcaatatac tgatcctcaa
    29701 acaacattga ctcatcagta tagaggagaa tctcctattt ttagtatcaa agatggaaaa
    29761 ttttctggtt tagtatctgc ctcaaaacca gacgaaaacc cgaagccaac gccaaaaccg
    29821 gatgagaaac caaaaccttc agcaccacaa caggagaaaa caaaacctac agttcagtct
    29881 ggttgggtag gttcatctta ttatcaaaat ggtaaaaaag tcactagtaa gtggattttt
    29941 gataaaaaat ataattcata cttctatcta gatgcatcag gaaattatgt tcaaaacgct
    30001 tgggtaggta actattatct caaatcaggc ggatacatgg ctaaaagtga gtggatttat
    30061 gataagaact atggttcata ctactatcta acatcagaag gcagctacgc tcgtaacact
    30121 tggtcaggca attattattt gaagtcaaat ggtaagatgg ctaaaagtga gtgggtatac
    30181 gatagtaact acaaatcata ttactacttg acatcagaag gaagttatgc tcgtaacact
    30241 tgggtaggca attactatct taaatcaaac ggtaaaatgg ctgttaatga acgtacacca
    30301 gatggttatc gtgtagatgg ttcaggtaaa tgggttaaat aagaaactaa aaaataggat
    30361 aataggtaat atcagatgaa taaaaaaaat tattttcatg tgctttagca ttttcaacga
    30421 ttggaacatt gtcaacgatt gataaatcag gagttcttcc tttttcagcg caaacggtgc
    30481 aggctgacat acaaacgctt accccaatgg caaaatatta tattattctt ccgaaggatg
    30541 cagaaatata taaaacttgg agaggtactg tcaatattcc cattattgat gctacaaaaa
    30601 ctactccaga attatcttat ttcaaagaag atcatcgcaa ctatatagct aatgagaata
    30661 agtctggtgc caattacata gagtggaagg gaacagtaga agagtttaaa gaggccatta
    30721 agaagttgac tgataaaaaa tcaactactg caacaccaaa aaaggatgaa aagccaacac
    30781 caaaaccgga tgagaagcca aaaccaacac ctacagttca gtctggttgg gtaggttcat
    30841 cctattatca agatggtaaa aaagtcatta gtaagtggat ttttgataaa aaatataatt
    30901 catacttcta tctagatgca tcaggaaatt atgttcaaaa cgcttgggta ggtaactatt
    30961 atcttaaatc aggcggatac atggctaaag gtgaatgggt ttatgatgcc acctatcaag
    31021 cttggtatta tttgacatca gatggttctt atgcttacag tacatggcaa ggaaattact
    31081 atctaaaatc ggatggtaaa atggctgtca atgaatgggt tgatggtgga cgttattatg
    31141 ttggcgctga cggagtttgg aaggaaggtc aagcaagtac agcttcttct agtaatgata
    31201 gcaatagtga atattctgct gctttaggaa aggcaaaaag ttataattcg ttattccaca
    31261 tgtcaaaaaa aaacgtatgt atagacaatt aacttctgat tttgataaat tttcaaatga
    31321 tgcagctcaa tatgccattg atcattagat gattaacaga tactggtagg cgaaaaaatt
    31381 ccttataatc catttacgca aacctttgca taagtgaatg gattttgata tactagtact
    31441 gtaagcattt tcaattacta cacaatgaaa aaggagaata tgatgagtca aaagattatt
    31501 gggattgacc ttggtggaac ttctatcaaa tttgcaatct taacaacagc aggagaaatc
    31561 caaggaaaat ggtcaatcaa gaccaacatt ttggatgagg gaagtcatat cgttgatgat
    31621 atgattgagt ctattcaaca tcgtttggac ttgcttggat tggcagcagc ggacttccaa
    31681 ggcattggaa tgggatcacc aggtgtggtt gaccgtgaca aagggactgt tatcggtgcc
    31741 tacaacttga actggaaaac ccttcaacca atcaaacaaa agattgaaaa agctttgggc
    31801 attccatttt tcatcgataa tgatgccaac gtagcagctc ttggtgagcg ctggatgggt
    31861 gctggagata accaaccaga cgttgtcttt atgacactcg gtactggtgt tggtggcggt
    31921 atcgtcgcag aaggcaaatt gcttcacggt gttgctggtg cagcaggtga gcttggtcac
    31981 atcactgttg actttgacca gccaatctca tgtacttgcg gtaagaaagg ctgccttgag
    32041 acagttgctt cagcaacagg gattgtcaac ttgactcgtc gctatgccga tgaatacgaa
    32101 ggcgatgcag ccttgaaacg cttgattgat aatggagaag aagtaactgc taagactgtc
    32161 tttgatctcg caaaagaagg agacgacctt gctttgattg tttaccgtaa cttctcacgt
    32221 tacttgggaa tcgcttgtgc taacattggt tcaatcctaa acccatcaac aatcgtcatc
    32281 ggtggtggtg tgtcagctgc gggagaattc cttctacaag gtgttcaaaa agtttacgat
    32341 gaaaatagtt tcccacaagt acgcacatct actaaattag ctcttgcaac tctaggaaat
    32401 gacgctggag ttatcggagc agcatcactt gtattgcaat aagataatga gagaggaaaa
    32461 tgctaaccta gagttagtaa tgttcctctt ttatttttta tgctatacta gttaggacaa
    32521 tgaatgaggt gagagtaaat gacaaaagca gatacgattt ttaaagagaa tattgaatgc
    32581 attctaaagg aaggtgtttt ctcagagcaa gctcgtccta agtacaagga tgggactgtt
    32641 gctaattcca agtatgtaac tggtgccttt tccgagtacg acttatctaa aggagaattt
    32701 cctatcacaa ccttgcgtcc cattgcaatc aaatccgcca tcaaagaagt tctctggatt
    32761 taccaagacc agtcaaatag cttagaagtg cttaatgaca agtacaatgt tcactactgg
    32821 aatgactggg aagttggaga cacgggaacc attggtgagc gctatggtgc cgttgttaag
    32881 aaacacgaca ttatcaataa gcttctcaaa cagttggaaa ccaatccttg gaatcgccgc
    32941 aatattattt cgctctggga ttaccaagct ttcgaagaaa cagatgggct gctcccgtgc
    33001 gcctttcaga ccatgtttga tgtccggcgt gttgatgggg aaatctatct ggatgcgacc
    33061 ttgacccagc gctccaatga tatgctggtg gcccaccaca tcaacgctat gcagtatgtg
    33121 gctttacaga tgatgattgc caaacatttt ggttggaagg ttgggaagtt cttctatttc
    33181 atcaacaacc tccatatcta tgataatcaa tttgaacaag ctcaggaatt gctccgtcgg
    33241 gagccgtcaa actgccaacc acgcttggtt ttaaatgttc ctgatgggac taatttcttt
    33301 gatatcaaag cagaagattt tgagttggtg gattatgacc ctgttaagcc acagttgaag
    33361 tttgacctag ctatttaaaa gaatagaaaa aagaagttga gaataatccc aacttctttt
    33421 gtttcttaac gtgatacgcg gcgacgagct gcttttttac gattttcttc gatgaaagct
    33481 gctttttgct cttctggttc gattactttc tttttaaatg cgtatactgc acctgcaacg
    33541 gcagcgacag ttcctgcgac acctgttaca agacctttag cgaatccttt agccatgagt
    33601 cttcctcctt tatattctca atcagccagc ctcctcaaga ggtcacattt ttctgactga
    33661 cctttttgtg ttataataat agtaacgaaa aaatgggaat ttttcaagga aaaaagatga
    33721 aaacaaaaat aattgtgatt gttggaccga ctgctgttgg aaagacggct ctagctattg
    33781 aagttgcaaa gcgctttaat ggcgaagtgg ttagtggaga tagccagcaa gtctatcgag
    33841 gacttgatat tgggacggcc aaggctagtc cagaagagca ggcagctgtt cctcatcatt
    33901 taatcgatgt tagagagata accgagtctt actcggcttt tgattttgtt tcagaagcta
    33961 agatgactat tgaggatatt cagagccgtg gcaagctagc cattatcgcc ggtgggactg
    34021 gactttatat ccagagcttg ctagaaggtt accacctagg tggggagact cctcatgagg
    34081 agattttagc ttatcgagct agtttggagc catattcaga tgaggaatta gcccatttgg
    34141 tggagcaagc aggccttgag attccccagt ttaatcgtcg tcgtgctatg cgtgccttag
    34201 aaattgccca ttttggtcag gatttggaaa atcaagagat cttgtatgaa ccgctgatta
    34261 tctgcttgga tgatgaacgt agtcaacttt atgagcgtat caaccaccga gtggatttga
    34321 tgtttgaggc tgggcttttg gatgaggcca agtggctgtt tgaccattcc cctaatgtac
    34381 aggctgctaa aggaattggc tataaggaac tctttcctta tttccgtgga gagcagacct
    34441 ttgaggaagc tcgtgagagt cttaaacagg cgacccgtcg ttttgccaag cgtcagctga
    34501 cctggttccg taatcgcatg caggtcacct tttatcagat tggagaatct ggtgtacaag
    34561 accgcatttt aagccagata gaggagtttt tagatgattg aaacggagaa aaaagaggag
    34621 cgagtcctgc tgattggtgt ggaattgcag ggtatggaca gttttgacct ctccatggaa
    34681 gaattggcta gtttagcgaa aacggcaggg gcagtcgttg tagatagcta cagacaaaaa
    34741 cgtgaaaaat atgattccaa gaccttcgtc ggctctggta agttggaaga gattgcgctt
    34801 atggtggatg cagaagaaat cactactgtc atcgtcaaca atcgtctgac cccaaggcag
    34861 aatgtcaatc tagaggaagt tctcggtgtt aaggtcattg accgtatgca gttgattttg
    34921 gatatctttg ccatgcgggc tcgaagccat gaagggaagc tccaagtcca cctagcccaa
    34981 ctcaaatacc tcttgcctcg cttggttggt caggggatta tgctcagccg tcaggcaggg
    35041 ggaattggtt cccgtggtcc tggtgaaagc caactggagc tgaaccgtcg tagcgttcgc
    35101 aatcaaatca cggatatcga gcgccagctt aaggtggttg agaaaaatcg tgcgactgtc
    35161 agagaaaaac gtttggagtc tagcactttt aagattggtt tgattggtta tactaatgct
    35221 gggaaatcaa ctatcatgaa catcttgacc agtaagaccc agtatgaagc agatgagctc
    35281 tttgcgactc tggatgcgac aaccaagagt attcatctgg gaggcaatct ccaagtaact
    35341 ttgacagata ccgttggctt tatccaagat ttgccgacag agttggtgtc cagtttcaag
    35401 tcaaccttgg aagaaagcaa gcatgtggac cttctggttc atgttatcga tgctagcaat
    35461 ccttaccacg aggagcatga aaaaacggtt ctctccatca tgaaagacct ggacatggaa
    35521 gatattcctc acttgacgct ttataataaa gcggatttgg tggaggattt cacgcctacc
    35581 caaacgccat ataccctcat ttctgccaag tctgaggaca gtcgtgaaaa cttgcaagca
    35641 ttattgctag ataagattaa ggaaattttt gaagcattta ccctgcgagt gcctttttca
    35701 aagtcctaca agattcatga tttagagagt gttgcaattc tggaagaacg tgattatcag
    35761 gaagacggcg aagtgattac aggctacatt tccgagaaaa ataaatggag gttagaagaa
    35821 ttttatgact gatattaaaa ctttggctct aaagtatgga ggttatacaa gtctggacaa
    35881 ggtctatctg gatcagcttc tagctggtaa aacagatcag gagcagttaa cacttattac
    35941 acctccgcca agtgttgtta atgcctactt tgcagaactc tatcagaaaa agagtcctca
    36001 ggctgcgacg gattattttg cagaactcag tcaggaactg aatctttaca atactgagcc
    36061 aagtttcacc ctagaaaata agccttttat tcggcttaat ctgtctggta aatcctttgg
    36121 tttttgttat gagagtgacg gccttggtcg gattttcttt gaaaatgagg agaaaatctc
    36181 ggatgacttg ctctttgaaa ttgcgcaaat tttcccccat caattagtct ttgaagagtc
    36241 tggtaagatt tacatgaagc ctgtcgagga cgaggaagtt atcagcctag aaagtctcac
    36301 agctttgact gatttggaaa gattggctga tggtcgaaaa cgtctcaaag gctacagcca
    36361 agaggattta ttgcaagaag ctgctgcttt ttctggcaaa cgctatttcc gatcggaaaa
    36421 ccgcacagcc atgttatata ttgattaatt agaaagtatc gaatggatat tcaattttta
    36481 ggaacggggg ctggtcagcc ctctaaagcc cgcaacgttt caagtctcgc cctgaaactt
    36541 ttggatgaga ttaacgaagt ttggctcttt gactgtggag aaggtacgca aaatcgcatt
    36601 ctggaaacca caattcgacc acgtaaggtc agcaaaatct ttattaccca tctgcatgga
    36661 gaccacattt ttggtttgcc aggtttcctt tctagccgtg cctttcaggc caatgaagag
    36721 cagacagatt tggaaatcta cggacctcaa ggaatcaagt catttgtctt aaccagcctt
    36781 cgtgtgtcag gttctcgtct gccctaccgc attcatttcc atgagtttga ccaagattct
    36841 ctgggtaaaa ttcttgaaac cgataaattc actgtgtatg cagaggagct ggaccacact
    36901 attttctgtg ttggctatcg tgtcatgcaa aaggatctag aagggacgct ggatgctgaa
    36961 aaactcaagg ctgctggtgt tccgttcggc ccgctttttg gtaaaatcaa aaacggccag
    37021 gatcttgttt tggaagacgg aactgaaatc aaggcagcag actatatctc agcgccacgt
    37081 ccaggtaaga ttatcactat tttaggagac actcgaaaaa cgggtgccag tgtgcgtctg
    37141 gctgtcaatg cagatgtcct agttcatgag tccacttatg gcaagggtga tgaaaaaatt
    37201 gctcgtaacc atggtcactc aactaatatg caagctgcac aagtagcggt agaagcaggt
    37261 gccaaacgcc tcctactcaa ccatatcagt gcccgtttcc tctcaaaaga tattagcaaa
    37321 ctcaagaaag acgctgccac aatttttgaa aatgtccatg tggtcaaaga cttggaagaa
    37381 gtggaaatct agcagtcaca gaaaggataa gtatgcctac tattctcatt accggagcta
    37441 gcggtggtct agctcaagaa atggtcaaac tcctgcccaa tgaccaactc atcttgcttg
    37501 gtagaaataa ggaaaaatta gcccaactct acggaaatta ttcccatgca gaattgattg
    37561 aaattgatat taccgacgat tcagccctag aagctctggt aactgatctt tatctccgct
    37621 atggcaagat tgatgtcttg attaacaacg ctggttacgg gatttttgag ggatttgacc
    37681 agattgctga taaagatatt caccagatgt ttgaggtcaa tacctttgcc ctgatgaatc
    37741 tgtctcgtca ccttgcggct cgtatgaagg aaagcagcaa agggcatatc atcaacatcg
    37801 tcagcatggc aggtctaata gctactggca agtctagtct ttactcagcg accaagtttg
    37861 cggctattgg tttttcaaat gctctgcgac tcgaacttat gccctatgga gtctatgtga
    37921 caacagtcaa tccaggtcca atccgaacag gatttttcga ccaagccgac ccagatggaa
    37981 cttatcttaa atcggttgac cgcttcctgc tagaaccaga tgcagtggct aaaaagattg
    38041 tcaagattat aggaaaaaac aaacgagaac tcaatctccc gattttgttg aacctagctc
    38101 ataagtttta taccctcttt cctaagctag ctgataagtt ggcaggggaa acttttaatt
    38161 ataagtaaaa agaaccaatg tgcaggttgt tgctagccta catattggtt cttatcattt
    38221 ctcaactatc aaactgaact tcttctagga gatagtctat aaagcgttcg cccatcttag
    38281 ataggctggt tttctcatgc tggatataga ccagctcgat cgggtcatca atatccagtg
    38341 ggatagaaac gatattgtct ccgtttaggt tgctgttcaa aatccctgtc gcaatggtat
    38401 aaccatccaa accaatcaag agattaaaga gggtggcacg gtcactgacc acaatggatt
    38461 tcttgtggtg ttcttgagaa agaatctctt ctgaaaagta gaaggaattg tgcgtccctt
    38521 ggtcatagct gaggtaaggg aaattctcca aatcagacag tttcaccttg tctttctttg
    38581 ccagagggtt ggtcttgctg acaaagatat gtggttgcgc tgtgaagaga tggtgggcta
    38641 gcaggtgatt gtcatccagc atcttggtta aaacatcacg gttgtaactg tttaagaaga
    38701 ggaccccgac ctcactgcgg aagttcttga cgtcgtcgat aatctcccaa gtccgagttt
    38761 cacgaaggaa gagttcgtat ttctccatat cgcttttctt gagcaaagag acaaaggcat
    38821 tgaccacaaa ggcatagtgt tgagacgaaa cgctaaatag ttcgcggtgg gcgacaggat
    38881 ttttatagcg ttcctccaga agctgggtct gctcgacaac ctgacgggca taagagagaa
    38941 actccatccc atcacgggtc aaggtgattc ccttgggatt gcggataaag atctcaatgc
    39001 ccatttcatt ttccaaatct cgcactgcat tggagagact tggctgagtg ataaagagtt
    39061 gcttggctgc ctcattcatg gagccagttt cgacgatttt gataatataa tgtaattgtt
    39121 gaattctcat gtttttattg taccatactt gccttagaat cgctaaagaa gataggaaaa
    39181 taaggagcat tgtgtgagtc tcttcttgaa aaaaacacaa aattttgcta gaatgagtct
    39241 tatgaaaaca ttctatgatg tgcagcaatt cctcaaacga tttggtatta ttgtttacat
    39301 gggaaaacgc ttatatgata ttgaactgat gaagttggaa ctatctcgga tttacgatgc
    39361 agggttgatg gataaattag actatctaga ggcagaagca gttcttcgca gagagcacaa
    39421 ggtagaattg gattatattg agaaaaatgg agaaaagaac taatggttac ttggattttg
    39481 tgggcactta tactagcaat gttggcgtgg atgggcttta actatcttcg tattcgccgt
    39541 gcggctaaaa ttgtggacaa tgaggagttt gaagccttga ttcgtacggg tcaattgatt
    39601 gatttgcgcg acccagcaga attccacaga aaacatatcc ttggtgcacg caatattcct
    39661 tcaagtcagt tgaaaactag tcttgcagcc cttcgtaaag ataaacctgt ccttctctac
    39721 gagaaccaac gtgcgcaacg agttacaaat gcagctcttt acttgaaaaa acaaggtttt
    39781 tctgagattt atatcctttc ttatggcttg gattcttgga aagggaaagt gaagactagc
    39841 taaccttatt tccaaattag tcgaatgata ggatgaagct attgttttat agtataatta
    39901 atttgtataa aatttaagga gttcttagaa cataaaagaa aagaagaaaa atccactttt
    39961 tgtgggtatc ttgtcgatta ttcttggttt gttatttcca attgtaggcc tgattttggg
    40021 tatcatagga ttggtcttgg ctatttcata ccaaaaagag tcataattag actataaaat
    40081 agaaaagatt cttaatatct taggaattgt gatttctgta gttaactgga ttgtagcaat
    40141 cgccttaatt tttcggtaaa taaaagaaaa aagctttagt tttaaagctt tttttgtttt
    40201 atcgactcat ctctaaatag tttttaatga tttgtaactc tttttggttc aaagggcggt
    40261 agttactttc tgctaaatct gggttcaatg tgaagtcccc aaattggatt ctcttgagga
    40321 tagtcacctt aacaccaacc gagaggaaca ttttcttgat ttgatgaaat tttccttctg
    40381 aaatggtgat agaggcttga ctgatggagg gacttgcaga tagaatctct agttttgcgg
    40441 gtttacagac agtaccatct aaaaagacaa ttcccttttg aaaggcttgg atatggtcag
    40501 gtgttagaag tccattaacc tcaacttgat aagtcttatc gacatgatat tggggatgga
    40561 ggagttggaa gcccaaggga ccgttatcgg tcaagaggag gagtcccgtt gtatctcggt
    40621 ccagtcggcc aacggcatag agcttgtcag actggatgtc agatggaagc aggtccatga
    40681 cggtcggaag ttccttgtct ttgttggctg taacgacacc agcaggttta tgaagcataa
    40741 gataggtgtg ttcatagcct tgaatgattc gatcctgaaa aaggagttct tgtagtcctg
    40801 tatcgatatt ttgagctagg gagcgggctg ggcaaccatc gactagaatt ttccctctga
    40861 ggagtgcttg cttcatggcc tttcggctga ttttttcttg ggctaataaa ttatctaaac
    40921 gcatactgtg cctatcttat cataagtcgc ttgctttgaa aaggcttgac gtgaaaagaa
    40981 aagcggagtg aaaacattta cacttgcttg agttatgtta tttatttgaa attatggtat
    41041 aatcgttcag ttagaaaata aattttgaat attatagagg aaatcatgac aaaattaaga
    41101 gaagatatcc gtaacattgc gattatcgcc cacgttgacc acggtaaaac aaccctggtt
    41161 gacgaattat tgaaacaatc agaaacgctt gatgcacgta ctgaattggc agagcgtgct
    41221 atggactcaa acgatatcga aaaagagcgt ggaatcacca tccttgctaa aaatactgcc
    41281 gttgcttaca acggaactcg tatcaacatt atggacacac caggacacgc ggacttcggt
    41341 ggagaagttg agcgtatcat gaaaatggtt gacggtgttg tcttggtcgt agatgcctat
    41401 gaaggaacca tgccacaaac tcgtttcgta ttgaaaaaag ccttggaaca agaccttgtc
    41461 ccaatcgtgg ttgttaacaa aatcgataag ccatcagctc gtccagcaga agtagtggat
    41521 gaagtcttgg aacttttcat cgagcttggt gcagatgacg accagcttga tttcccagtg
    41581 gtttatgctt cagcgatcaa cggaacttct tcattgtcag atgatccagc tgaccaagaa
    41641 gcgactatgg caccaatctt tgacacgatt atcgaccata tcccagctcc agtagataac
    41701 tcagatgagc ctttgcagtt ccaagtgtca cttttggact acaatgactt cgttggacgt
    41761 atcggtatcg gtcgtgtctt ccgtggtaca gttaaggttg gggaccaagt taccctttct
    41821 aaacttgacg gtacaactaa aaacttccgt gttacaaaac tcttcggttt ctttggtttg
    41881 gaacgtcgtg aaatccaaga agccaaagcg ggtgacttga ttgccgtttc aggtatggaa
    41941 gacatctttg tcggtgaaac catcactccg acagatgcag tagaagctct tccaatccta
    42001 cacatcgatg agccaactct tcaaatgact ttcttggtca acaactcacc atttgctggt
    42061 aaagaaggta aatgggtaac ttctcgtaag gtggaagaac gcttgcaggc ggaattgcaa
    42121 acagacgttt cccttcgtgt tgacccaact gattcaccag ataaatggac tgtttcagga
    42181 cgtggagaat tgcacttgtc aatccttatc gaaacaatgc gtcgtgaggg ctatgaactt
    42241 caagtatctc gtccagaagt tatcgtaaaa gaaatcgacg gtgttaaatg tgaaccattt
    42301 gaacgtgtac aaatcgacac tccagaagaa taccaagggt ctgttatcca aagcctttct
    42361 gaacgtaaag gtgaaatgtt ggatatgatt tcaactggta atggtcaaac tcgtttggtc
    42421 ttccttgttc cagcgcgtgg tttgattgga tactcaactg agttcttgtc aatgactcgt
    42481 ggttacggta tcatgaacca taccttcgac caatacttgc cattgattcc aggggaaatt
    42541 ggtggacgtc accgtggtgc ccttgtttct atcgatgctg gtaaggctac aacttactca
    42601 atcatgtcta tcgaagaacg tggtacgatc tttgtcaacc caggtactga ggtttatgaa
    42661 ggaatgatca tcggtgaaaa ctctcgtgaa aatgacttga cagttaacat cacgaaggca
    42721 aaacaaatga ccaacgttcg ttcagctact aaggaccaaa cagctgttat caagacgcct
    42781 cgtatcttga cacttgaaga gtctcttgag ttcttgaacg acgatgagta catggaagta
    42841 acgcctgagt ctatccgttt gcgtaaacaa atccttaaca aagcagagcg tgagaaagct
    42901 aacaagaaga aaaaatcagc tgaataagag ctagaaagag agaaagatgg tctatttagt
    42961 cctaggaatt ttactgctcc tactctatgt atttgcgaca ccagaaagca ttaaagggac
    43021 agtcaatatc gtcgctatgg tatgtatttt agtggcactc ttgattttat tggttctatc
    43081 ttttctgaaa atttttcaat taccaacaga aatattccta gcaatagcca tgttgctcct
    43141 agcttacttt agtgttagag acattacact catgccagtc aaaaaaagta aaagaagata
    43201 aaaaagagag ttttggctct cttttttgct aggaatttta caagattgca atttattttt
    43261 gagttatcac catctctttt gtttggataa tatgaatggg aaaaacttga ataaaattcg
    43321 ttaatggaat ctattttata
//
LOCUS       DAVLAQ010000010        41699 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000010 DAVLAQ010000000
VERSION     DAVLAQ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.010"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            444..1919
                     /locus_tag="VXB71_000533"
     CDS             444..1919
                     /locus_tag="VXB71_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0450694.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(1885..2600)
                     /locus_tag="VXB71_000534"
                     /pseudo
     CDS             complement(1885..2600)
                     /locus_tag="VXB71_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            2856..3716
                     /gene="speE"
                     /locus_tag="VXB71_000535"
     CDS             2856..3716
                     /gene="speE"
                     /locus_tag="VXB71_000535"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0450695.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            3713..4972
                     /locus_tag="VXB71_000536"
     CDS             3713..4972
                     /locus_tag="VXB71_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0450696.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            4972..6099
                     /gene="nspC"
                     /locus_tag="VXB71_000537"
     CDS             4972..6099
                     /gene="nspC"
                     /locus_tag="VXB71_000537"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0450697.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6096..7181
                     /gene="aguA"
                     /locus_tag="VXB71_000538"
     CDS             6096..7181
                     /gene="aguA"
                     /locus_tag="VXB71_000538"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0450698.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7191..8066
                     /gene="aguB"
                     /locus_tag="VXB71_000539"
     CDS             7191..8066
                     /gene="aguB"
                     /locus_tag="VXB71_000539"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0450699.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8247..9056)
                     /locus_tag="VXB71_000540"
     CDS             complement(8247..9056)
                     /locus_tag="VXB71_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0450700.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9328..9549
                     /locus_tag="VXB71_000541"
     CDS             9328..9549
                     /locus_tag="VXB71_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0450701.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            9603..10274
                     /locus_tag="VXB71_000542"
     CDS             9603..10274
                     /locus_tag="VXB71_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0450702.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10326..10523)
                     /locus_tag="VXB71_000543"
     CDS             complement(10326..10523)
                     /locus_tag="VXB71_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0450703.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            10516..11424
                     /locus_tag="VXB71_000544"
     CDS             10516..11424
                     /locus_tag="VXB71_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0450704.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11421..11882
                     /locus_tag="VXB71_000545"
     CDS             11421..11882
                     /locus_tag="VXB71_000545"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0450705.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            11872..12759
                     /locus_tag="VXB71_000546"
     CDS             11872..12759
                     /locus_tag="VXB71_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0450706.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            12762..14645
                     /gene="cbpE"
                     /locus_tag="VXB71_000547"
                     /gene_synonym="pce"
     CDS             12762..14645
                     /gene="cbpE"
                     /locus_tag="VXB71_000547"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0450707.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVARHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            14725..15855
                     /locus_tag="VXB71_000548"
     CDS             14725..15855
                     /locus_tag="VXB71_000548"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0450708.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            15865..17127
                     /locus_tag="VXB71_000549"
     CDS             15865..17127
                     /locus_tag="VXB71_000549"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0450709.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17131..17928
                     /gene="proC"
                     /locus_tag="VXB71_000550"
     CDS             17131..17928
                     /gene="proC"
                     /locus_tag="VXB71_000550"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0450710.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            18044..18682
                     /locus_tag="VXB71_000551"
     CDS             18044..18682
                     /locus_tag="VXB71_000551"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0450711.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            18679..19569
                     /locus_tag="VXB71_000552"
     CDS             18679..19569
                     /locus_tag="VXB71_000552"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0450712.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            19609..19926
                     /gene="yabA"
                     /locus_tag="VXB71_000553"
     CDS             19609..19926
                     /gene="yabA"
                     /locus_tag="VXB71_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0450713.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            19929..20798
                     /gene="rsmI"
                     /locus_tag="VXB71_000554"
     CDS             19929..20798
                     /gene="rsmI"
                     /locus_tag="VXB71_000554"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0450714.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            21025..21543
                     /locus_tag="VXB71_000555"
     CDS             21025..21543
                     /locus_tag="VXB71_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0450715.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            21652..22300
                     /locus_tag="VXB71_000556"
                     /pseudo
     CDS             21652..22300
                     /locus_tag="VXB71_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(22289..23092)
                     /locus_tag="VXB71_000557"
                     /pseudo
     CDS             complement(22289..23092)
                     /locus_tag="VXB71_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23087..23341
                     /locus_tag="VXB71_000558"
     CDS             23087..23341
                     /locus_tag="VXB71_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0450716.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            23587..24921
                     /gene="trmFO"
                     /locus_tag="VXB71_000559"
     CDS             23587..24921
                     /gene="trmFO"
                     /locus_tag="VXB71_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0450717.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            25005..25742
                     /locus_tag="VXB71_000560"
     CDS             25005..25742
                     /locus_tag="VXB71_000560"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0450718.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            25751..26308
                     /gene="frr"
                     /locus_tag="VXB71_000561"
     CDS             25751..26308
                     /gene="frr"
                     /locus_tag="VXB71_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0450719.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            26368..27222
                     /gene="cvfB"
                     /locus_tag="VXB71_000562"
     CDS             26368..27222
                     /gene="cvfB"
                     /locus_tag="VXB71_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0450720.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            27231..27446
                     /locus_tag="VXB71_000563"
     CDS             27231..27446
                     /locus_tag="VXB71_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0450721.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            27532..28500
                     /locus_tag="VXB71_000564"
     CDS             27532..28500
                     /locus_tag="VXB71_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0450722.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(28478..28657)
                     /locus_tag="VXB71_000565"
     CDS             complement(28478..28657)
                     /locus_tag="VXB71_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450723.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            28693..29193
                     /locus_tag="VXB71_000566"
     CDS             28693..29193
                     /locus_tag="VXB71_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450724.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            29196..29456
                     /locus_tag="VXB71_000567"
                     /pseudo
     CDS             29196..29456
                     /locus_tag="VXB71_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(29823..30149)
                     /locus_tag="VXB71_000568"
     CDS             complement(29823..30149)
                     /locus_tag="VXB71_000568"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450725.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(30095..30508)
                     /locus_tag="VXB71_000569"
     CDS             complement(30095..30508)
                     /locus_tag="VXB71_000569"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0450726.1"
                     /translation="MGAHFLTKQAGGSGVLPSGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(30509..30934)
                     /locus_tag="VXB71_000570"
     CDS             complement(30509..30934)
                     /locus_tag="VXB71_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0450727.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            31111..31680
                     /locus_tag="VXB71_000571"
     CDS             31111..31680
                     /locus_tag="VXB71_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450728.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            31748..32398
                     /locus_tag="VXB71_000572"
     CDS             31748..32398
                     /locus_tag="VXB71_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0450729.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            32382..34622
                     /locus_tag="VXB71_000573"
     CDS             32382..34622
                     /locus_tag="VXB71_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0450730.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            34764..34988
                     /locus_tag="VXB71_000574"
     CDS             34764..34988
                     /locus_tag="VXB71_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450731.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEIINYYSGGY"
     gene            35021..35608
                     /locus_tag="VXB71_000575"
     CDS             35021..35608
                     /locus_tag="VXB71_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450732.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            35612..36793
                     /locus_tag="VXB71_000576"
     CDS             35612..36793
                     /locus_tag="VXB71_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450733.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    36953..37084
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            37100..37630
                     /gene="infC"
                     /locus_tag="VXB71_000577"
     CDS             37100..37630
                     /gene="infC"
                     /locus_tag="VXB71_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0450734.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            37663..37863
                     /gene="rpmI"
                     /locus_tag="VXB71_000578"
     CDS             37663..37863
                     /gene="rpmI"
                     /locus_tag="VXB71_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0450735.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            37915..38274
                     /gene="rplT"
                     /locus_tag="VXB71_000579"
     CDS             37915..38274
                     /gene="rplT"
                     /locus_tag="VXB71_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0450736.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            38332..38712
                     /locus_tag="VXB71_000580"
     CDS             38332..38712
                     /locus_tag="VXB71_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0450737.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            38962..39762
                     /locus_tag="VXB71_000581"
     CDS             38962..39762
                     /locus_tag="VXB71_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0450738.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            39773..40711
                     /locus_tag="VXB71_000582"
     CDS             39773..40711
                     /locus_tag="VXB71_000582"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0450739.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKVTNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            40753..>41699
                     /gene="lytB"
                     /locus_tag="VXB71_000583"
     CDS             40753..>41699
                     /gene="lytB"
                     /locus_tag="VXB71_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0450740.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKE"
BASE COUNT        12533 a         7550 c         9495 g        12121 t
ORIGIN      
        1 tttttatcaa aaaatacttt acaagttctt aaaaacatga tatagtaata aagcttagaa
       61 aatgagatga tgttttctag caaatataaa cccgagtaaa aaatgcctac ggacaggcag
      121 ggttgaatgc cgaagcgtgg ttgaaaagcc acattattga tagggttaaa agcctacttt
      181 tataagttga tgttaggaca cttgtcctaa ttcataaatt tttagtgtgg tgaaagcaca
      241 cgtcatcttg tgaaacgatc aataaagtac gtaatatttg ctactagaga gttaggaaac
      301 atcgggaaca gacatactca acagaaacca aaataaacac gtcagaagat tgcagagcag
      361 gtgaaaacct gctctttttt catgagtcaa cctttagttc cttagttttc ataaggtcct
      421 aaaaatattg aaaggagtat gttttgaaag agttagatca aaaccaagcc ccaatttatg
      481 aggccttggt gaagttacgc aagaaaagga ttgttccctt tgatgttcca ggtcacaagc
      541 gtggacgggg aaatccagaa cttgtcgaac tcttaggaga aaaatgtgta ggcattgatg
      601 tcaattcgat gaaacccttg gataatttag gccatcctat ttcgattatt cgtgatgcag
      661 aggagctggc tgcagatgct tttggagcta gccatgcctt tctaatgatt ggtggaacaa
      721 cttcatcggt gcagactatg attctggcaa cctgcaaggc aggagataag attattctgc
      781 cacgaaatgt ccataaatct gctatcaatg cgttggttct atgtggtgcc attcccatct
      841 atatcgagat gagtgtagat cctaagattg gtatcgcttt aggtcttgaa aatgaccgag
      901 tagcacaggc cataaaggac catccagatg ctaaggctat cctaatcaac aatcctactt
      961 actacggcat ctgttcagac ctaaaggggt tgacagaaat ggctcatgaa gctggcatga
     1021 tggttttagt agatgaagcc catggagcgc atttgcattt cactggtaaa cttccaattt
     1081 ctgctatgga tgcaggagct gatatggcag cagtttccat gcataagtct ggtgggagtt
     1141 tgacacaaag ttcgcttctt ttaatcgggg agcagatgaa ttctgaatac gttcgtcaga
     1201 taattaacct gactcagtct acatctgcct cttacttgtt gatggctagt ttggatattt
     1261 cacgtcgcaa cttggccctt cgtggtaaag agtcgtttga gaaagtcatt gagctatctg
     1321 agtatgcccg ccgtgaaatc aatgctatcg gtggctacta tgcctactca aaagagttaa
     1381 tagacggtgt ttcggtttgc gattttgacg taactaagct gtcagtttac actcagggta
     1441 ttggcttaac aggtatcgag gtttatgacc tcttgcgaga cgaatacgac attcagatcg
     1501 agtttggtga tatcggcaat atcttggcct atatttccat cggcgaccgc atccaagaca
     1561 tcgagcgctt ggttggtgct ctggctgata ttaagagact ctattcaaga gatggaaaag
     1621 atttgatagc aggagaatat attcagcccg agttggtgct gtctccacaa gaagccttct
     1681 attcagagag aaaaagtttg accttagatg agtctgttgg acaggtctgt ggagaatttg
     1741 tcatgtgcta tcctccaggg attcctatct tggctcctgg tgaacgcatt acacgagaaa
     1801 ttgtagacta tatccaattc gccaaggaac gtggttgctc cctccaaggg acggaagatc
     1861 cagaggtcaa tcatatcaac gttattaaga gaaagacaaa ctataagaaa agtcaatagt
     1921 tttatctaaa ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca
     1981 aaaagccctt gaattagaag cggtcaatcg cttaatttct atcagcttat caaatcctgc
     2041 ctcaatcctt ttctgaggat tagggtagcg tgtcaagagt tggtaggtat attctgaatg
     2101 ctttccaacg attttatcca actcaggaaa gatgatatca agacaacgag tgtattgtac
     2161 tttccaatca gactgttttt cttgagacga tgaatatgtc tagccagtat ttttagttct
     2221 acttgccgat tatcgtgttg aaattgttca cgattggggt cagaaagaag tttaagagcg
     2281 atgccatgag cgtctttctt atccgtttta gtcttgtgaa gtgataatga tttggcaaat
     2341 tccttgatga gcaaaggatt gtaggtgtaa actttatatc cttgttcatg caggaagttc
     2401 agtagattaa aggcataatg tccggtattt tcaagagcga tgagacagtc ttggttgagt
     2461 tgtcgaagag acagatctaa gagttcaaaa ccagctttat tatttgaaaa agtgagtggt
     2521 ttaagaacag tttttcctgg aacattcaag gctgtaacat cgtgtttatt tttagcgaca
     2581 tcaatgccca cataaagcat gggagtacct ccagatgtag tatttcaagt ctacttggtt
     2641 atccacgaat tttttgcctt gttaccttag acgagataaa acgtctatgc gttatcaaac
     2701 tcattaccaa ttgaaacaaa aaactgtggt tagagccttt cggaaatcgt caagcgattg
     2761 gagggaataa actaatccac agtggcttat tccaagtata ccacttgggc tttggcagta
     2821 gctaactgcg ctaaatataa tataaggaga aatagatgga tttatggttt tctgaagttc
     2881 atactccaga tgtcaaattg tctctgagaa cagccaagca actttacgct ggaaaaagtg
     2941 aatggcagga tatcgaagtc ttggatacgc cagcttttgg gaaaatactg attttaaatg
     3001 gccatgtctt gttctcagat gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc
     3061 ccatggctgt ccacccaaat ccaaagaaag tattggttat tgggggtggt gacggcggtg
     3121 ttgcccaagt attaacactc tatcctgaac tggaacaaat cgatatcgtg gaaccggatg
     3181 agatgttggt cgaggtctgt cgtgagtatt tcccagactt tgctgcaggg ctagatgatc
     3241 ctcgtgttac catttactac caaaatgggc tacgcttttt gcgaaactgc gaagatgatt
     3301 acgatattat catcaacgat gcgacagatc catttggcca tacggaagga ctctttacca
     3361 aggaattcta cggcaatagt tatcgagctc tgaaggaaga cggcatcatg atttaccagc
     3421 atgggagtcc cttctttgac gaggatgagt cggcctgccg aagcatgcac cgcaaggtca
     3481 atcaagcctt tccaatcagt cgggtttatc aggcccatat tccaactagc ccagctggct
     3541 attggttgtt tggatttgca tcgaaaaaat accaccctgt caaagatttt gacaaggaag
     3601 gttggaaaaa acgccagctt ttcacagaat actacactgc aaacttacac gtgggatcct
     3661 ttatgttgcc caagtatgtt gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg
     3721 tttactagtt attggttgtg ggggcgttgc ccaagttgct atttcaaaga tttgtcaaga
     3781 tagcgaaaca tttacagaga ttatgattgc tagccgtacc aagtcaaaat gcgatgactt
     3841 gaaagcgaag ctagaaggca aaacaagtac taaaattgaa actgcagcac ttgatgctga
     3901 caaggttgaa gaagtgattg ccctgattga aagctacaaa ccagaagctg ttttgaatgt
     3961 agctctgcct tatcaagatt taaccattat ggatgcttgt ttggcaacag gtgttcacta
     4021 tatcgataca gccaactacg aagcagaaga cacagaagac cctgagtggc gtgctatcta
     4081 cgaaaaacgt tgtaaggaac ttggttttac agcctacttt gactactcat ggcagtgggc
     4141 ttatcaagag aaattcaaag aagcaggctt gactgctctt cttggttctg gttttgaccc
     4201 aggtgtaact agtgtctttt cagcttatgc cctcaaacac tattttgatg aaatccatta
     4261 tatcgacatt ttagactgta atggcggtga ccacggttat ccatttgcaa ccaactttaa
     4321 tccagaaatt aatctccgtg aggtttctgc gccaggttct tactgggaag atgggaaatg
     4381 ggtcgaagtc gaagctatgt ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa
     4441 agatatgtat ctccttcacc atgaagaaat cgaatcattg gccaagaaca ttccaggtgt
     4501 caaacgcatt cgtttcttta tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct
     4561 tgaaaatgtt ggactccttc gtacggatac cattaacttt aacggccaag aaattgttcc
     4621 aattcaattt ttgaaagcct tgcttccaga tcctgctagc cttggcccac gtactgtagg
     4681 taaaaccaat attggatgta tctttacagg tgtcaaagat ggcgttgaaa agactatcta
     4741 catctacaat gtttgcgacc atcaagagtg ctatgcagaa gtcgggtcac aagcaatttc
     4801 atacacgaca ggcgttccag ccatgattgg gacaaaatta gtcatgaacg gaacttggaa
     4861 acaagctgga gtgtataacc ttgaggagtt agatccagat ccattcatgg aagctttgaa
     4921 tgagtatggt ttgccatggg ttgtggttga aaatccacaa atggtggact aatgaagtta
     4981 gaacaagtac caacaccagc ctatgttatt gacttggcca agttagaagc taattgccgc
     5041 attctacaat atgtacaaga agaggccggt tgcaaggtct tgcttgccca gaaggcatat
     5101 tccctctaca aaacttatcc cttgattagc cagtatctat caggtacgac agctagtgga
     5161 ctctatgagg ccaaattggc aagggaagaa tttcctggtg aagtccatgt ttttgcacca
     5221 gctttcaagg atgaggacat ggaggaattg cttgggataa cagaccatat cgtctttaac
     5281 tcagagagac agttgcgtaa gcatggggct cgttgtcgag aggctggtgt cagtgttggt
     5341 ttgcgcctca accctcagtg ttcaactcaa ggagatcacg cgctctatga cccttgtgca
     5401 cctggttctc gctttggagt tactatagac aagattccga gtgatttgct agatttggtt
     5461 gacggacttc attttcatac cctttgcgag cagggagcag atgatttaca aacaactttg
     5521 aaagcagtag aagaacagtt tggtccctac ttacatgagg taaaatggct caatatgggt
     5581 ggtggtcatc atattacaag agaaggttac gatgtggatt tgctgatttc agaaatcaag
     5641 cgtatccgaa aaacttacaa tcttgaaatc tatatcgagc ctggtgaagc cattgcgctt
     5701 aatgcgggtt atttagcaac tgaggtatta gatattgtag aaaacggtat ggaaatcttg
     5761 gttttagacg cctctgcgac ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca
     5821 cctttgagaa atggctttga gtcacaggaa aaagcccata cctacagact ttcttctaat
     5881 acctgtctga ctggcgatgt gattggtgat tatagttttg aaaatccagt ccaaatcgga
     5941 gacagacttt attttcaaga catggccatt tattcttttg tcaaaaataa tacctttaat
     6001 ggtattggat tgccaagtct ctatctcatg gacgaacagg gagactgtag cttactcaaa
     6061 gcttttggct atcaagactt taaagggaga ttatcatgat ggacagtcca aaaaaattag
     6121 gctatcacat gccagcagag tacgaacccc atcatggtac cctcatgata tggccgactc
     6181 gaccaggatc atggcctttt caaggaaagg ctgctaaaag agcatttact cagatcatcg
     6241 agaccatagc agaaggggaa agagtctatc ttttggtgga gcaggcctat ctatctgaag
     6301 cccaatccta tcttggagac aaggttgttt atttagacat tcccaccaat gatgcctggg
     6361 cgcgtgatac tggcccaacc attctcgtca atgataaagg taagaaatta gccgtggatt
     6421 gggcctttaa tgcttgggga ggcacctatg atggtcttta tcaagattat gaagaggatg
     6481 accaagtagc cagtcgtttt gctgaggcct tggaaaggcc tgtctatgat gctaaacctt
     6541 ttgtactgga aggaggcgca atccatagcg atggtcaagg aactattctc gtaactgaaa
     6601 gttgcttgct tagtcctggt cgcaatccta acctgactaa agaggagatt gaaaacacat
     6661 tattagaaag tcttggtgct gaaaaagtta tttggcttcc ttatggtatt tatcaggatg
     6721 aaaccaatga acacgtcgat aatgttgttg cctttgttgg tcctgctgag gttgttttgg
     6781 cttggacaga tgacgaaaat gatccccagt atgccatgtc aaaagcagat ctcgaactct
     6841 tagaacagga aacagatgca aaaggttgtc acttcaccat tcataaattg cctatccctg
     6901 cagttcgaca agttgtgaca gaagaagatt tgccaggcta catctatgaa gaaggagaag
     6961 aagagcgata cgcaggtgaa cgactagcag cttcctacgt aaacttttat atcgccaaca
     7021 aggctgtctt ggttccacag tttgaggatg taaacgacca agtggcctta gatatcctca
     7081 gcaagtgttt cccagaccgt aaagttgtcg gaataccagc cagagatatt ctcttaggtg
     7141 gtggcaatat ccactgtatc acccaacaaa ttccagaata ggagaaaaag atgagaaatg
     7201 taagagttgc aaccattcag atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg
     7261 cagagcgttt agtacgtcag gctgctgagc aaggagccca aattattctc ttgcccgagt
     7321 tgtttgaaca tccctatttc tgtcaggaac gtcagtatga ctactaccag tatgcccaat
     7381 ctgtagcgga aaatactgcc attcagcatt ttaaggtgat tgccaaggaa ctacaagttg
     7441 ttttaccaat cagtttctat gaaaaagatg gtaatgtctt gtataactct attgccgtca
     7501 ttgatgcaga tgggggagtg ctgggcgttt atcgaaagac ccatatacca gatgaccatt
     7561 attatcaaga aaaattctat ttcacgcctg gtaacactgg tttcaaggtc tggaatactc
     7621 gctatgctaa gattggtatc ggtatctgtt gggatcaatg gttccctgaa acagcccgct
     7681 gtcttgcatt gaatggtgct gaattgctct tttatcctac agctatcggt tcagagccaa
     7741 ttttggatac agatagttgt ggtcactggc aacgtactat gcaagggcac gcagcagcga
     7801 atattgttcc agtcatcgca gccaatcgtt atggtttaga ggaggttact cctagtgagg
     7861 aaaatggcgg acagagttcc agtcttgact tctacggttc ctcctttatg acggatgaaa
     7921 caggagctat tctagaacga gctgaaagac aagaagaagc tgttctgtta gctacttatg
     7981 acctagacaa gggagcaagt gaacgtctaa actggggctt gtttcgagat agaagaccag
     8041 aaatgtatag acaaattaca gattagtgtg ggagaaatga gagattcatt ctgctagact
     8101 aacttcttat tagcaactat aagatactat ggcatctagt aaatcgattt ttatgattcg
     8161 ctattcttgt ctattgatta gtccgtattt taaaatatta gcaaaaaagc aaatagcagt
     8221 aacttctgtc tatttgcttt tcttttttat agaatatatt tctcaatagc acgcgcaacg
     8281 ccgtcttctt cgttgcttga ggtaacggca tccgcaagag atttgacata atcgctggca
     8341 tttcccattg caatcccaag ccctgcaaac tggagcattt cgatatcgtt attagcatcg
     8401 cccatggcca taatctctga ggaatcaatc ttcaaaatct cagctagtcg tgaaagagca
     8461 gtagcctttg tcgttccaag cggcattgct tcataaatga caggctgcga acgaactcca
     8521 ctgaatcgtt ggcaaagctc ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt
     8581 gttcctaaaa acataccttg gaacatccgg aactttccac tagtcgcttc ttcaagagaa
     8641 atttcagtca ggtctgaaaa tactagttta gcatcatttt caataacttg attgggtttg
     8701 ccaccgagaa caaaataatg tgactcgtca aaaagtgtca actgaacatc actcttttca
     8761 gcaaggtcat agaggtattc gatgtcagct ggactcagtt ctttccagtc aactagactc
     8821 caatcactgg tctggtgagt tgaacaaccg ttgttaacaa taatatattc gttctggagg
     8881 tcaagctcca gttttttgta gtaggggagg acaccgaaaa gggggcgacc cgtacagaga
     8941 accagtttga cacctttttc aatggctttg tgaatagcag taatgtgagc ttgtgggatt
     9001 tccttggctt cattgaggag ggtgccgtcc atatccaagg ctagtagttt aatcataggt
     9061 cttccttctt tatcttttgc tattattata gcatattttg gagaagaaat tgatagaaag
     9121 cttgagacta attgatttta tagtttaaga tgttttgatg acaattcatg atttgaagag
     9181 gatatttggc aaagatatgc tatactatgt ttgtcaatgt tgcaactaga caaattaaaa
     9241 aaccaactta atataatagt ttttttgtaa gtaggtatga gtatcagatt actcaactaa
     9301 tctgaagaat aatggaggaa atatatcatg attttaatga caaaaaatat aaatctaaca
     9361 aatgaagaat tagagctgat acaaggtgga gcagattcat atggtaaaaa tcctaatggt
     9421 aggtacgatt gggaaataga accagtatta actctgccgg ttcatggatt ttgttccaga
     9481 ggcacctatg atttaggata tattggagga ggcaatcatc tttgcaaagg aagtgctgcg
     9541 agattttaag taaaatttat tagtaatatg aagaaacaag tggagaaagc agagaattta
     9601 atatgaaaaa acgggctatt caaattttac tagcattgtc cttaattttt tacaaatcaa
     9661 cttggttttg gagagttttc aatcacctcg caaagcccta tctaccagca agtcgtgaat
     9721 tttttcagat tctgcttttg atggagagcg gagttctttt cttagcggtc atctatctac
     9781 tggtttttgc aggaaagaaa atttttcatt tcaagtggca gctgaggtac ttcatctacc
     9841 ttttactggg ctacatcatt tcatatatgt ctgacttcct cttttcgtat ttcatatccc
     9901 tgtcttcaaa tcagatttct ttgaatgaaa cgatagaaat gatggggaga caggagttcc
     9961 cttatttctt gctcatcgtt tgcttcatcg cccctattgc tgaggaattg atttatcgag
    10021 gtgtgcttat gacaaccttt ttcaaaaact caccttggta cggagatgtt ttgctttctg
    10081 ctattatttt cggttatatt catatcaatt ttgctttaac tcctcttgct tttttcattt
    10141 atgctagtgg aggtctgatt ttagctctat tgtatcgcat gactaaaaat ctctactatc
    10201 caatactagt tcatattctc atcaatatca ctgccttctg ggatgtttgg ttactcctat
    10261 tttcaggaag ttagcttact aaaaaaatgt cggaattttc cggcattttc ttttttcaca
    10321 aatagtcaac gtttttcttt ccgatactga agtggtgtgt agccacttat ttttttgaat
    10381 tgattttgaa aataagattg gcgtgagaaa ggcagatagt gaagatagtt aagaagaata
    10441 ggatgttctt ttttcctttt tggaaaactt ctaaaatatg gtataatgaa aagataaaga
    10501 agttgggggt agaagatgaa cattcaacaa ttacgctatg ttgtggctat tgccaatagt
    10561 ggtacttttc gtgaagctgc tgaaaagatg tatgttagtc agccgagtct gtctatttct
    10621 gttcgtgatt tggaaaaaga gttgggcttt aagattttcc gtcggaccag ctcagggact
    10681 ttcttgaccc gtcgtgggat ggaattttat gaaaaagcgc aagaattggt taaaggattt
    10741 gatatttttc aaaatcagta tgccaatcct gaagaagaaa aagatgaatt ttccgttgct
    10801 agccagcact atgacttctt accaccaact attacggcct tttcagagcg ctatcctgac
    10861 tataagaact tccgtatttt tgaatcaact actgttcaaa tattagatga agtggcgcaa
    10921 gggcatagtg agattgggat tatctacctc aacaatcaaa ataaaaaggg gattatgcaa
    10981 cgggttgaaa agttaggtct ggaggtcatc gaattgattc ctttccatac ccatatttat
    11041 ctctgtgagg gtcatccttt agcccagaaa gaggaattag tcatggagga tttagcggat
    11101 ttaccaacgg ttcgtttcac tcaagagaaa gacgagtacc tttattattc agagaacttt
    11161 gtcgatacca gcgctagctc acagatgttt aatgtgacag accgtgccac cttgaatggt
    11221 attttggagc ggacggacgc ctatgcgaca ggttctggat ttttagatag tgacagtgtt
    11281 aatggcatta cagttattcg tctcaaggat aacctagata accgcatggt ctatgttaaa
    11341 cgtgaagaag tggagcttag tcaagctggg actctcttcg tagaagtcat gcaagaatat
    11401 tttgatcaaa agaggaaatc atgaaaaaaa gagcaatagt ggcagtcatt gtactgcttt
    11461 taattgggct ggatcagttg gtcaaatctt atatcgtcca gcagattcca ctgggtgaag
    11521 tgcgctcctg gatccccaat ttcgttagct tgacctacct gcaaaatcga ggtgcagcct
    11581 tttctatctt acaagatcag cagttgttat tcgctgtcat tactctggtt gtcgtgatag
    11641 gtgccatttg gtatttacat aaacacatgg aggactcatt ctggatggtc ttgggtttga
    11701 ctctaataat cgcgggtggt cttggaaact ttattgacag ggtcagtcag ggctttgttg
    11761 tggatatgtt ccaccttgac tttatcaact ttgcaatttt caatgtggca gatagctatc
    11821 tgacggttgg agtgattatt ttattgattg caatgctaaa agaggaaata aatggaaatt
    11881 aaaattgaaa ctggtggtct gcgtttggat aaggctttgt cagatttgtc agaattatca
    11941 cgtagtctcg cgaatgaaca aattaaatca ggccaggtct tggtcaatgg tcaagtcaag
    12001 aaagctaaat acacagtcca agagggtgat gtcgtcactt accatgtgcc agaaccagag
    12061 gtattagagt atgtggctga ggatcttccg ctagaaatag tctaccaaga tgaggatgtg
    12121 gctgtcgtta acaaacctca gggaatggtt gtgcacccga gtgctggtca taccagtgga
    12181 accctagtaa atgccctcat gtatcatatt aaggacttgt cgggtatcaa tggggttctg
    12241 cgtccaggga ttgttcaccg tattgataag gatacgtcag gtcttctcat gattgctaaa
    12301 aacgatgatg cgcatctagt acttgcccaa gaactcaaag ataaaaagtc tctccgcaaa
    12361 tattgggcga ttgttcatgg aaatctgcct aatgatcgtg gtgtaattga agcgccgatt
    12421 ggccggagtg aaaaagaccg taagaaacag gctgtaactg ctaaagggaa gcctgcagtg
    12481 acgcgttttc acgtcttgga acgctttggc gattatagct tagtagagtt gcaactggag
    12541 acagggcgca ctcatcaaat ccgtgtccac atggcttata tcggccattc agtcgctggt
    12601 gatgaggtct atggtcctcg caagactttg aaaggacatg gacaatttct tcatgccaag
    12661 actttaggtt ttactcatcc gagaacaggt aagaccttgg aatttaaagc agatatccca
    12721 gagattttta aggaaacctt ggagagattg agaaagtaag aatgaaaaag aaattaacta
    12781 gtttagcact tgtaggcgct tttttaggtt tgtcatggta tgggaatgtt caggctcaag
    12841 aaagttcagg aaataaaatc cactttatca atgttcaaga aggtggcagt gatgcgatta
    12901 ttcttgaaag caatggacat tttgccatgg tggatacagg agaagattat gatttcccag
    12961 atggaagtga ttctcgctat ccatggagag aaggaattga aacgtcttat aagcatgttc
    13021 taacagaccg tgtctttcgt cgtttgaagg aattgggtgt ccaaaaactt gattttattt
    13081 tggtgaccca tacccacagt gatcatattg gaaatgttga tgaattactg tctacctatc
    13141 cagttgaccg agtctatctt aagaaatata gtgatagtcg tattactaat tctgaacgtc
    13201 tatgggataa tctgtatggc tatgataagg ttttacagac tgctgcagaa aaaggtgttt
    13261 cagttattca aaatatcaca caaggggatg ctcattttca gtttggggac atggatattc
    13321 agctctataa ttatgaaaat gaaactgatt catcgggtga attaaagaaa atttgggatg
    13381 acaattccaa ttccttgatt agcgtggtga aagtcaatgg caagaaaatt taccttgggg
    13441 gcgatttaga taatgttcat ggagcagaag acaagtatgg tcctctcatt ggaaaagttg
    13501 atttgatgaa gtttaatcat caccatgata ccaacaaatc aaataccaag gatttcatta
    13561 aaaatttgag tccgagtttg attgttcaaa cttcggatag tctaccttgg aaaaatggtg
    13621 ttgatagtga gtatgttaat tggctcaaag aacgaggaat tgagagaatc aatgcagcca
    13681 gcaaagacta tgatgcaaca gtttttgata ttcgacaaga cggtttagta aacatttcaa
    13741 cttcctacaa gccgattcca agttttcaag ctggttggca taagagttca tatggaaact
    13801 ggtggtatca agcgcctgat tctacaggag aatatgctgt cggttggaat gaaattaagg
    13861 gtgaatggta ttactttaac caaacgggta tcttattaca gaatcaatgg aaaaaatgga
    13921 acaatcgttg gttctatttg acagactctg gtgttgctgc taaaaattgg aagaaaatcg
    13981 ctggaatctg gtattatttt aacaaagaaa accagatgga aattggttgg attcaagata
    14041 aagagcagtg gtattatttg gatgttgatg gctctatgaa gacaggttgg cttcaatata
    14101 aggggcaatg gtattacttt gctccatcag gggaaatgaa aacgggctgg gtaaaagata
    14161 aagaagcctg gtactatatg gattctactg gtatcatgaa gacaggtgag atagaagttg
    14221 ctagacatca ttactatcta gaagaatcag gagctatgaa gcaaggctgg cttaaaaagg
    14281 caaatgattg gtatttctac aagacagatg gttcacgagc tataggttgg attaaagaca
    14341 aggataaatg gtacttcttg aaagaaaatg gtcaattact tgtgaatggt aagacaccag
    14401 aaggctatac tgtggattca agtggtgcct ggttagtgga tgttccgatc gagaaatctg
    14461 ctacaattaa aactacaagt cattcagaaa taaaagaatc caaagaagta gtgaaaaagg
    14521 atcttgaaaa taaagaaacg agtcaacatg aaagtgttac aaattcttca actagtcaag
    14581 atttgacatc ctcaacttca caaagctctg aaacgagtgt aaacaaatcg gaatcagaac
    14641 agtagtagaa aagaaggttt tagggccttc tttttcctat caactctttt ctatttcctg
    14701 ttattcatgt tataatggat aaatatgaat aatcggagtg agactatgaa atacaaacgg
    14761 attgtcttta aggtgggtac ttcttctctg acaaatgagg atggaagttt atcacgtagt
    14821 aaggtaaagg atattaccca gcagttggct atgctgcacg aggctggtca tgagttgatt
    14881 ttggtgtctt caggtgccat tgcggctggt tttggagcct taggatttaa aaagcgtccg
    14941 actaaaattg ctgataaaca ggcttcagca gcggtagggc agggactttt gttggaagaa
    15001 tatacgacca atcttctctt gcgtcaaatc gtttctgcac aaatcttgct gacccaagat
    15061 gactttgtgg ataagcgtcg ttataaaaat gcccatcagg ctttgtcggt tttgctcaac
    15121 cgtggggcaa ttcctatcat caatgagaat gatagtgtcg ttattgatga gctcaaggtt
    15181 ggggacaatg acactctaag tgctcaagta gcggcgatgg tccaagcaga ccttttagtt
    15241 ttcttgacag atgtggacgg tctctatact ggaaatccta attcagatcc aagagccaaa
    15301 cgcttggaga gaatcgagac catcaatcgt gagattattg atatggctgg tggagctggt
    15361 tcgtcaaacg gaactggggg tatgttaacc aaaatcaagg ctgcaactat cgcgacggaa
    15421 tcaggagttc ctgtttatat ctgctcatcc ttgaaatcag attccatgat tgaggcggca
    15481 gaggagaccg aggatggttc ttactttgtt gctcaagaga aggggcttcg tacccagaaa
    15541 caatggcttg ccttctatgc tcagagtcaa ggttctattt gggttgataa aggggctgcg
    15601 gaagctctct ctcaacatgg aaagagtctt ctcttatctg gtatcgttga agcagaagga
    15661 gtcttttctt acggtgatat cgtgacagta tttgataagg aaagtggaaa atcacttgga
    15721 aaaggacgcg tgcaatttgg agcatctgct ttggaggata tgttgcgttc tcaaaaagcc
    15781 aagggtgtct tgatttaccg tgacgactgg atttccatta ctcctgaaat ccaactactt
    15841 tttacagaat tttagaggta aactatggtg agtagacaag aacaatttga acaggtacag
    15901 gctgttaaaa aatcgattaa cacagctagt gaagaagtga aaaaccaagc cttgctagcc
    15961 atggctgatc acttagtggc tgctactgag gaaattttag cggctaatgc cctcgatatg
    16021 gcagcggcta aggggaaaat ctcagatgtg atgttggatc gtctttattt ggatgcagat
    16081 cgtatagaag cgatggcaag aggaattcgt gaagtggttg ccttaccaga tccaatcggt
    16141 gaagttttag aaacaagtca gcttgaaaat ggtttggtta tcacaaaaaa acgtgtagct
    16201 atgggtgtca tcggtattat ctatgaaagc cgtccaaatg tgacgtctga tgcggctgct
    16261 ttgactctta agagtggaaa tgcggttgtt cttcgtagtg gtaaggatgc ctatcaaaca
    16321 acccatgcca ttgtcacagc cttgaagaag ggcttggaga cgactactat tcatccaaat
    16381 gtgattcaac tggtggagga tactagccgt gaaagtagtt atgctatgat gaaggccaag
    16441 ggctatctag accttctcat tcctcgtgga ggagctggct tgatcaatgc agtggttgag
    16501 aatgcgattg tacctgttat cgagacaggg actgggattg tccatgtcta tgtggataag
    16561 gatgcagacg aagacaaggc gctgtctatc atcaacaatg ctaaaaccag tcgtccttct
    16621 gtttgtaatg ccatggaggt tctgctggtt catgaaaaca aggcagcaag catccttcct
    16681 cgcttggatc aaatgctggt tgcagatcga aaagaagctg ggttggaacc aattcaattc
    16741 cgcctagata gcaaagcaag ccagtttgtt tcaggtcaag ctgctcaagc acaagacttt
    16801 gataccgagt ttttagacta tattctagct gttaaggttg tgagcagttt agaagaagcg
    16861 gttgcgcata ttgaatccca cagtacccat cattcggatg ctattgtgac ggaaaatgct
    16921 gaagctgcag catactttac agatcaagtg gactctgcag cggtgtatgt taatgcctca
    16981 actcgtttca cagatggagg acaatttggt cttggttgtg aaatggggat ttctactcag
    17041 aaattgcacg cgcgtggtcc aatgggcttg aaagagttga ccagctacaa gtatgtggtt
    17101 gctggtgatg ggcagataag ggagtaagag atgaagattg gatttatcgg tttggggaat
    17161 atgggtgcta gcttggcaaa atctgtcttg cagactagga cgtcagatga gattctcctt
    17221 gccaatcgta gtcaagctaa ggtagatgct ttcattgcag actttggtgg tcaggcttcc
    17281 agcaatgaag aaatgtttgc agaagcagat gtgatttttc taggagttaa gcctgctcag
    17341 ttttctgaac tgctttctca atatcagacc atccttgaaa aaagagaaag tcttcttttg
    17401 atttcgatgg cagctggatt gaccttagaa aaactagcaa gtcttatccc aagccaacac
    17461 cgaattattc gtatgatgcc taatacccct gcttctatcg ggcaaggagt gattagttat
    17521 gccttgtctc ctaattgcag ggctgaggac agtgagatct tttgtcagct tttagccaag
    17581 gctggtctct tggttgaatt aggagaaagc ttaatcaatg cagcgacagg tcttgcaggt
    17641 tgtggaccag cctttgtcta tctctttatt gaggccttgg cagatgcagg tgttcagacg
    17701 ggattaccac gagaaacagc cttgaaaatg gcagcccaaa ctgtggtagg agctgggcaa
    17761 ttggtcctag aaagccagca acatcctgga gttttgaaag atcaagtttg tagtccaggc
    17821 ggttcgacta ttgctggcgt agcaagctta gaagcgcatg cttttcgagg catagtcatg
    17881 gaggcagttc atcaagccta taaacgaaca caagaactag gtaaataaga ggtagctttg
    17941 actgcctctt ttatggtggc tgaaatgaga agacacaaaa agattgtcac aaactcctat
    18001 ttttttgata gaatagaagt agtaaaaaag aaatgagtta gacatgtcaa aaggattttt
    18061 agtctctctt gagggaccag agggagcagg caagaccagt gttttagagg ctctgctacc
    18121 aattttagag gaaaaaggag tagaggtgct gacgacccgt gaacctggcg gagtcttgat
    18181 tggggagaag attcgggaag tgattttgga tccaagtcat actcagatgg atgctaaaac
    18241 agagctactt ctctatattg ccagtcgcag acagcatttg gtggaaaaag ttcttccagc
    18301 ccttgaagct ggcaagttgg tcatcatgga tcgttttatc gatagttctg ttgcctatca
    18361 gggatttggt cgtggcttag atattgaagc cattgactgg ctcaatcagt ttgcgacaga
    18421 tggcctcaaa cccgatttga cactctattt tgacatcgag gtggaagaag ggctggctcg
    18481 tattgctgct aatagtgacc gcgaggttaa tcgtttggat ttggaagggt tggacttgca
    18541 taaaaaagtt cgtcaaggct acctttctct tctggataaa gagggaaatc gcattgtcaa
    18601 gattgatgct agtctccctt tggagcaagt tgtggaaact accaatgctg tcttgtttga
    18661 cggaatgggc ttggccaaat gaaacaagat caactaaagg cttggcaacc agctcagttt
    18721 gaccgttttg tccgtatctt agaacaagac cagctcaatc acgcctatct cttttcaggt
    18781 ttctttggaa gcttggaaat ggcgcaattt ttagctaaga gccttttttg tacggataaa
    18841 gttggcgtct taccatgtga gaaatgccga agttgcaagc tgattgaaca ggaagagttt
    18901 ccagatgtca ccttgattaa gccagtcaat caggtcatca agacagaacg tattcgggaa
    18961 ttggtgggac agttttctca agcagggatt gaaagccagc aacaggtctt tatcatcgag
    19021 caagcggata aaatgcatcc caacgcagcc aattctctgc tcaaggtcat cgaagaaccc
    19081 cagagtgaag tttatatttt cttcttgact agcgatgagg aaaagatgtt accgacaatc
    19141 cgaagtcgga ctcagatctt ccactttaaa aagcaagaag aaaaacttat cttactctta
    19201 gaacaaatgg gacttgttaa gaaaaaagcg actcttttag ctaagtttag tcaatcgcga
    19261 gctgaagcag aaaagttggc acatcaggca agtttttgga ccttggtcga tgaaagtgaa
    19321 cgcctgctga cttggttagt agctaagaaa aaagaaagtt atctacaggt tgccaaatta
    19381 gccaacttgg cagatgataa ggaaaaacag gatcaggttt tacggattct tgaagttctc
    19441 tgtgggcagg acctcttgca ggtaagagta agagtgattc tacaagattt actagaagct
    19501 agaaaaatgt ggcaagctaa tgtcagcttt caaaatgcca tggaatatct ggtcttgaaa
    19561 gaaatataaa ctcaaaaatg aatgataaag aaaggaaagg gctgttttat ggacaaaaaa
    19621 gaattatttg acgcgctgga tgatttttcc caacagttat tggtaacctt ggccgatgtg
    19681 gaagccatca agaaaaatct caagagcctg gtagaggaaa atacagctct tcgtttggaa
    19741 aattctaagt tgcgagaacg cttgggtgag gtggaagcag atgctcctgt caaggccaag
    19801 catgttcgtg aaagtgtccg tcgcatttac cgtgatggat ttcacgtatg taatgatttt
    19861 tatggacaac gtcgagagca ggacgaggaa tgtatgtttt gtgacgagtt gctatacagg
    19921 gagtaggcat gcagattcaa aaaagtttta aggggcagtc tccctatggc aagctgtatc
    19981 tagtggcaac gccgattggc aatctagatg atatgacctt tcgagctatc cagaccttga
    20041 aagaagtaga ttggattgct gctgaggata cgcgcaatac aggtcttttg ctcaagcatt
    20101 ttgacatttc caccaagcag atcagttttc atgagcacaa tgccaaggaa aaaattcctg
    20161 atttgattgg tttcttgaaa gcagggcaaa gtattgctca ggtctctgat gccggtttgc
    20221 ctagcatttc agaccctggt catgatttag ttaaggcagc tattgaggaa gaaattgcag
    20281 ttgtgacagt tccaggtgcc tctgcaggaa tttctgcctt gattgccagt ggtttagcgc
    20341 cacagccaca tatcttttac ggttttttac cgagaaaatc aggtcagcag aagcaatttt
    20401 ttggcttgaa aaaagattat cctgaaacac agatttttta tgaatcacct catcgtgtag
    20461 cagacacgtt ggaaaatatg ttagaagtct acggtgaccg ctccgttgtc ttggtcaggg
    20521 aattgaccaa aatctatgaa gaataccaac gaggtactat ctctgagtta ttagaaagca
    20581 ttgctgaaac gccactcaag ggcgaatgtc ttctcattgt tgagggtgcc agtcagggtg
    20641 tggaggaaaa ggacgaggaa gacttgttcg tagaaattca aacccgcatc cagcaaggta
    20701 tgaagaaaaa tcaagctatt aaggaagtag ctaagattta ccagtggaat aagagtcaac
    20761 tctacgctgc ctaccacgac tgggaagaaa aacaataaag ggagatagga tgtaataatt
    20821 ctgtctgttt ctgtttaact taattagtga tgataatata aagatgtatc acttggtata
    20881 gaagctttgg tattaagttt tttattaagc ccatacggaa taccgatggt tggagcagca
    20941 gttatagcgt tcttagaagg tataaataga aaaataaggt cattttaaat caaaggattg
    21001 ataaatcaga aagaaggtga ttttttgcga acatacgaaa ataaagaaga actaaaagct
    21061 gagatagaga aaacatttga gaaatatatt ttagaatttg ataatattcc agaaaattta
    21121 aaagataaga gagctgatga agttgacaga actccagcag aaaaccttgc ttatcaggtt
    21181 ggttggacca acttggttct taaatgggaa gaagatgaaa gaaaggggct tcaagtaaaa
    21241 acaccatcgg ataaatttaa atggaatcaa cttggtgaat tatatcagtg gttcacagat
    21301 acctacgctc atttatctct gcaagagttg aaagcaaaat taaatgaaaa tattaattct
    21361 atctctgcaa tgattgattc gttgagtgag gaagaattat ttgaaccgca tatgagaaag
    21421 tgggctgatg aagcgactaa aacagcgact tgggaagtgt ataagtttat tcatgtaaat
    21481 acggttgcac cttttggaac tttcagaact aaaatcagaa aatggaagaa gatagtatta
    21541 taaattatat ttttaacttt aaaaaatttc ataaaaatgg ttaccaaagg cgatagaaga
    21601 aaaactatcg tctttttctt tgcaaatttt taagaaggga ggtgatcttg catggacttt
    21661 gaatattttt ataacagaga agcggaaaga tttaacttct taaaagtacc ggagatatta
    21721 gttgatagag aagaatttcg gggcttatca gcagaagcaa ttatccttta ttccatactt
    21781 cttaaacgga caggaatgtc atttaagaat aactggatag acaaggaagg cagagtattt
    21841 atctatttta ctgtcgaaga aattatgaaa agaagaaata tctcaaagcc aactgccata
    21901 aaaacattag atgagcttga tgtaaaaaaa aggaatagga ctgatcgaaa gagtaaggct
    21961 tggacttggt aagccgaaca tcatttatgt taaagacttt atgagtatat ttcaggtaaa
    22021 agaaaatgac ttacaaaagt caaaaaactt aacttcagaa gtaaaagatt ttaacctcag
    22081 aagtaaagaa aatgaacttc aagaggttaa gaaccttgac tctaactata tagagaataa
    22141 taagagtaag tatagtaaga gagaatatag ttttggtgaa aacggacttg gaacatttca
    22201 aaatgtgttt ttagctgttg aagatatatc ggatttacaa atcataatga actcacagct
    22261 tgagaattac attagacttc ctgcaaaact agaatcctag ttcatgattg ataataccag
    22321 caatcaaatt cattcgtaat ccgaagcgtt tacgatgatt tcgataggtt gttgaaaaca
    22381 ttttaaacgt ttttactttg gcaaagatgt tctcaacctt gcttctttcc ttagatagcg
    22441 catggttata ggctttatct tcagctatta gcgacttgag tttgctggat ttacgtggag
    22501 tttgtacttg aggatatatc ttcatgagcc cttgataacc actgtcagcc aagattttac
    22561 cagcttgtcc gatatttctg caactcattt tgaacaactt catatcacga caatagttca
    22621 cagtgatatc caaagaaaca attctccctt gacttgtgac aatcgcttga gccttcatag
    22681 cgtggcattt ctttttacca gaatcattcg ctaattcttt ttttagggcg attgatttgt
    22741 acttccgtcg catcaatcat taccgtgtcc tcagagctga gaggagttct tgaaaccgta
    22801 acaccacttt gaacaagagt tacttcaacc cattggctcc gacggataaa gttgctttcg
    22861 tgaataccaa aatcagccgc aatttgttca taagttcgat attctcgcac tattgaagag
    22921 tggccataag aaggtcttct aggcttaatt taggttttcg tccacctttt gcgtgtttaa
    22981 gttgataagc tgtttttaat acagctaata tctcttcaaa agtcgtgcgc tgaacaccaa
    23041 caagacgctt aaatcgtgca tcagttagtt gtttacttgc ttcatcattc atagaactac
    23101 tataccatat tttgtttcgc aggaagtcta ttggaaagta agaaatattg aagctgaggc
    23161 tattagaaga aattgtgagc gtggtgctat tttttcaggt aaaataaaat atcacgaaga
    23221 ttcacagttt aaaggagatc actatgttga atgttatgct gttttagata atacggttat
    23281 agcaagagat agaataacag tccctatcga tccgttatgt ggaaaagatt ttatagagta
    23341 gcatataatt gattcttaac tggaatactc tttatctctt tacatcaaga aaatgactaa
    23401 acagggaagt ttgccttctt cccttttttt gttatactag tagaagaaaa aaatagaaag
    23461 atttgtggga gtgaaaaagt cctgtggact ttttcagcct gagccaagaa actcgaaagc
    23521 tcgtaagtct gattggcttt ttcaatgtga atcttaactt catactccca aagaggtatt
    23581 agtgtcgtgt ctcaatctta tatcaatgtt atcggtgctg gtttggcagg ttctgaagca
    23641 gcctaccaaa tcgcagagcg tggtattcca gttaaacttt atgaaatgcg tggtgtcaag
    23701 tcaacacctc agcacaaaac agacaatttt gctgagttgg tttgttccaa ttccttgcgt
    23761 ggagatgctt tgacaaatgc tgttggcctc cttaaggaag aaatgcgtcg cttgggttct
    23821 gtgattttgg aatctgctga ggctacacgt gttcctgcag gtggtgccct tgcagtggac
    23881 cgtgatggtt tctctcaaat ggtgaccgaa aaagttgcca accacccctt gattgaagtg
    23941 gttcgtgatg aaattacaga attgccgaca gatgttatta cggttatcgc tactggtcct
    24001 ttgacaagtg atgccttggc tgaaaagatt catgccctta atgacggtga tggtttttat
    24061 ttctacgatg cggcagcgcc tattatcgat gtcaacacta tcgatatgag caaggtctac
    24121 ctcaaatcac gttatgataa gggagaagcg gcctacctca atgcccctat gaccaagcaa
    24181 gaatttatgg atttccatga agctttggtc aatgcagaag aagcaccgct taattctttt
    24241 gaaaaagaaa agtactttga aggatgtatg cctatcgaag tcatggccaa acgtggcatt
    24301 aaaaccatgc tttatggtcc tatgaaacca gttggtcttg agtatccgga cgactacaca
    24361 ggacctcgtg atggagaatt taaaacacct tatgcggttg tccagctccg tcaggataat
    24421 gcagctggta gcctatacaa tattgttggt ttccagaccc acctcaaatg gggagaacaa
    24481 aagcgtgtct tccaaatgat tccgggtctt gaaaatgcgg agtttgtccg ttatggtgtc
    24541 atgcatcgca attcttacat ggattcacca aatcttcttg agcagactta ccgttccaag
    24601 aaacaaccaa atctcttctt tgctggtcag atgacggggg tggaaggcta tgttgagtcg
    24661 gcggcttcgg gcttagttgc gggaattaac gcagctcgtc tcttcaagga agaaagcgag
    24721 gttattttcc ccgagacgac agcgattgga agcttagctc attacattac ccatgccgac
    24781 agcaaacatt tccaaccaat gaatgtcaat tttgggatca tcaaggagtt ggaaggcgag
    24841 cgtatccgtg ataagaaggc tcgttatgaa aaaattgcag agcgtgccct tgccgactta
    24901 gaggaatttt tgactgtcta atttttttga aagaattgct catgatacta taaaaatctt
    24961 agaaattgtg ataaaatagg taggatgaaa gaaggagagt gaaaatggcg aatcccaagt
    25021 ataaacgtat tttaatcaag ttatcaggtg aagcccttgc cggtgaacgt ggcgtaggga
    25081 ttgatatcca aacagttcaa acaatcgcaa aagagattca agaagttcat agcttaggta
    25141 tcgaaattgc ccttgttatt ggtggaggaa atctttggcg tggagaacct gcagcagaag
    25201 caggtatgga ccgtgttcag gcagattaca ctggaatgct tgggactgtt atgaatgctc
    25261 ttgtgatggc agattcattg caacaagttg gggttgatac gcgtgtacaa acagctattg
    25321 ctatgcaaca agtggcagag ccttatgtcc gtggacgtgc ccttcgtcac cttgaaaaag
    25381 gccgtatcgt tatctttggt gctggaattg gttcaccata cttctcgaca gatacaacag
    25441 cggcccttcg tgcagctgaa atcgaagcag atgccatcct catggctaaa aatggcgtcg
    25501 atggtgtgta caatgccgat cctaagaagg acaagacagc cgttaagttt gaagaattga
    25561 cccaccgtga tgttatcaac aaaggtcttc gtatcatgga ctcaacagcc tcaaccctct
    25621 caatggacaa cgacattgac ttggttgtct tcaacatgaa ccaatcaggc aacatcaaac
    25681 gtgtcgtatt tggtgaaaat atcggaacaa cagtttcaaa taatatcgaa gaaaaggaat
    25741 aagaaagaat atggctaacg taattattga aaaagctaaa gagagaatga cccaatctca
    25801 ccaatcactt gctcgtgaat ttggtggtat ccgtgctggt cgtgccaatg caagcttgct
    25861 tgaccgtgta catgtagaat actatggagt cgaaactcct cttaaccaaa tcgcttcaat
    25921 tacgattcca gaagcgcgtg ttttgttggt aacaccattt gacaagtctt cattgaaaga
    25981 catcgaacgt gccttgaacg cttctgatct tggtatcaca ccggctaatg acggttctgt
    26041 gattcgcttg gttatcccag ctcttacaga agaaactcgt cgtgaccttg ctaaagaagt
    26101 gaagaaggtc ggcgaaaatg ctaaagtggc tgtccgcaat atccgtcgcg atgctatgga
    26161 cgaagctaag aaacaagaaa aagcaaaaga aatcactgaa gacgaattga agactcttga
    26221 aaaagatatt caaaaagtaa cagacgatgc tgttaaacac atcgacgaca tgactgctaa
    26281 caaagagaaa gaacttttgg aagtctaaaa ataaacagaa aaactcagtt ggcattgctg
    26341 gctgagtttt attcgaaaga aggaaatatg aatacaaatc ttgcaagttt tatcgttgga
    26401 ctgatcatcg atgaaaatga ccgtttttac tttgtgcaaa aggatggtca aacctatgct
    26461 cttgctaagg aagaaggtca acatacagta ggggatacgg tcaaaggttt tgcatacacg
    26521 gatatgaagc aaaaactccg cctgacaacc ttagaagtga ctgccactca ggaccaattt
    26581 ggttggggac gtgtcacaga ggttcgtaag gatttgggtg tctttgtgga tacaggcctt
    26641 cctgacaagg aaatcgttgt gtcactcgat attctccctg agctcaagga actctggcct
    26701 aagaagggcg accaactcta catccgtctt gaagtggata agaaagaccg tatctggggc
    26761 ctcttggctt atcaagaaga cttccaacgt cttgctcgtc ctgcctacaa caacatgcag
    26821 aaccaaaact ggccagccat tgtttaccgt ctcaagctgt caggaacttt tgtttaccta
    26881 ccagaaaata atatgcttgg ttttattcat cctagcgagc gttacgcaga gccacgtttg
    26941 gggcaagtat tagatgcgcg cgttattggt ttccgtgaag tggaccgcac tctgaacctc
    27001 tccctcaaac cacgctcctt tgaaatgttg gaaaacgatg ctcagatgat tttgacttat
    27061 ttggaaagta atggcggttt catgacctta aatgataagt catctccaga cgacatcaag
    27121 gcaacctttg gcatttctaa aggtcagttc aagaaagctt taggtggtct tatgaaggct
    27181 ggtaaaatca agcaggacca gtttgggaca gagttgattt agggaggctt atgagaaaat
    27241 cattttacac ttggctcatg accgagcgca atcctaaaag taacagtccc aaagcaattt
    27301 tggcagacct cgcttttgaa gaggcagctt ttccaaaaca tacagatgat tttgatgagg
    27361 tcagtcgctt tttggaggag catgccagtt tctcttttaa cctaggagat tttgacagca
    27421 tttggcagga atatctagaa cactagcatt tattcattgg gtttgggcta gtaatttctc
    27481 catccctctg ctataataaa aagaaataaa aggattagag aggttcttta tttgaaggaa
    27541 cattcaatag acattcaact gagtcatcca gatgacctgt ttcatctttt tggttccaat
    27601 gaacgccatc ttcgtttgat ggaagaagag cttgatgttg tgattcatgc tcgtacggag
    27661 attgtccagg ttttgggaga agagtctgcc tgtgaggaag cccgtcaagt tattcaggct
    27721 ttgatggtct tggtaaatcg tgggatgacc gttggtacgc cagatgtagt cactgcgatt
    27781 agcatggtca aaaatgatga aattgacaag tttgtcgccc tttacgaaga agaaattatc
    27841 aaagataata ctgggaaacc tatccgtgtc aaaaccctag ggcaaaagct ttatgtggac
    27901 agtgtcaaac agcatgatgt gacctttgga attgggccag caggtacagg gaagaccttc
    27961 cttgcagtga ccttggcagt gactgccctt aaacgtgggc aagtcaagcg aattatccta
    28021 actcgtccag cggtggaagc gggagagagt cttggatttc ttccgggtga tcttaaggag
    28081 aaggtggatc cttaccttcg tcctgtttac gatgccttgt atcagattct ggggaaagac
    28141 caaacaactc gactcatgga gcgtgaaatt atcgagattg cgccccttgc ctatatgcgt
    28201 ggacggacct tggatgatgc ctttgtcatt ctcgatgagg cgcaaaatac gaccatcatg
    28261 cagatgaaga tgttcttgac tcgtttaggt tttcattcta agatgattgt caatggagat
    28321 attagtcaga ttgacctgcc acgtaatgtc aagtccggtt tgattgatgc tcaagagaaa
    28381 ctcaagaaca tccatcagat tgactttgtt catttttcag ccaaggatgt ggttcgccat
    28441 ccagttgtcg ctcagattat ccgagcctat gaatattcta ctgaagttgc acacgactga
    28501 ttttgaggaa gtttgcctgc aaaagaatat acttttgaga gaggaaaatc cagttgtata
    28561 ggctaaaggt tttatccaaa ggtttgagac aacgattagg cacgatggaa agaactttta
    28621 tgtggctgat gacgatcagt gcatcttcct gtgtcataat cacagtgcac aagaaagtag
    28681 gaatttgaaa agatgattga ccaactatct aagtattaca gttgtaggat actaactgaa
    28741 aaggatattc caagtatttt atctttatat gaaagtaatc ctctgtattt tcagcattgt
    28801 ccaccagagc caaattttgc aactgtaaaa gaggacatgc tttgtctacc tgaaggtaaa
    28861 gctaaggctg ataagttttt tgttggattt tggaatggat ctgaccttgt ggctgttata
    28921 gattttgtct atgcacatcc tgatgaggag actgttttta ttggtttgtt tatggttgat
    28981 caagcctatc agaggaaagg gattggtagt catattgtga cagaagcact agcttatttt
    29041 gctaagaact ttcgaaaggc acgtttggct tatgttaagg gaaatccgca atctcagcat
    29101 ttttgggaaa agcagggctt taaatcaatt ggatgcgagg ttaagcaaga actctatacg
    29161 gttgttatcg ctgaacagag cctagaagat tagaaatggc atcaagtaag aactatttgg
    29221 aatttgtttt ggaacaatta tcaggattag atgatgtgac ttaccgttcc atgatggggg
    29281 agtatattct ttacttccgc ggcaagatta ttggcggcat ttatgacgat cgctttttag
    29341 ttaaacccgt gcaagcagtc ttagataaga ttgaccaatc ttcttttgag tttccataca
    29401 aaggtgccaa agaaatgatt tgagtggaag aacttgataa taagatgttt ctataagacc
    29461 tgattttagc tatgtataac caactgccaa cgcccaaacc taaaaagaaa aagcaagggt
    29521 gaacgaagta aaaaagaagt ctgctaaggc cctgtctttg cacgggtaaa attttatata
    29581 taaaaagaag ctgggactaa agagctcagc ttcctttggt ttatataatt gtcattacaa
    29641 gacgaagtgg ttgggcgaaa ctctgttgac tttattcaat ttagagtttc ttatgcacaa
    29701 ttgagtctgg aacgaaagtc tccagttgca aagtatacag tacaataaac caacgatgta
    29761 atagctgatg acacaaagca cagtgggtag gacttgcgaa gtcacccttt tcttttcaaa
    29821 atttatacta aatcattgat atcagtgtag tcacgattaa gtccttgagc aactggtagg
    29881 ctagtcaagt aaccttgata agtggtcaca ccttgacgca agccttcatc ttcagagatt
    29941 gcttgtgcga atcctttgcc agccaaagct tcgatataag gaagagtgac attggttagg
    30001 gcgatggttg aagtgcgggc aaccgcacca gggatattgg caacggcata gtggagaaca
    30061 ccgtgttttt catagacggg ttcatcgtgc gttgtcacac ggtcagctgt ttcgataacg
    30121 ccaccttggt caacagcaac gtcaacgata cagagcctgg acgcatttgt ttgaccatct
    30181 catctgtcac caattccggt gcttttgcac cagggatgag aatggctcca atcaccacat
    30241 cagcatctct catacttgct tcaatgttga atgaattaga tataagagtt tgaatttgac
    30301 ttccaaagac ttcttctaga actgagagac gcttggcact aatatctaaa atagtcactt
    30361 gagcaccaag accaagggcg atgcgggcag catgtgtacc gacgacacca tcaccgatga
    30421 tagttacttt tccttttgga acacctggta caccactagg tagaacacca gagccaccag
    30481 cttgcttagt aaggaagtga gctccgattt aaacagccat acgacctgca acctcactca
    30541 taggaacgag gagcggtagt tgtccttgat tgtcacgaac agtttcatag gcaattcctg
    30601 ttgtttttgc tgctaacata gcatctgcta attctggagc agcggccatg tgcaagtagg
    30661 tgaagagaag aagatcgtcg cgcaagtaac cgtattcaga acttaaaggt tcttttactt
    30721 tcacaaccaa ctctgctgcc caagcttcac cagcagtagc gacaatctca gctccttgct
    30781 tttgatagtc agcatcagta aagccagaac cgagaccagc atttgtttcg ataaggacac
    30841 gatgaccacg actaactaag ctatgaacac ctgcaggtgt gagggcgaca cggttttcgt
    30901 tatttttaat ttcttttggg attccgatta acattgagat aacctacctt tcaattgacg
    30961 gtcttgtttt ggttgtcaca ttccagttca taaatcaaaa atgtgacggt ttcattgtat
    31021 atgaaaccgc ttcaaaaatc aagaaaaact tgtcatccaa atttttttat gctagactag
    31081 tgaaaatcaa gctctaatgg agggaaaagt atggaatcaa tatttgtgaa atttgcccag
    31141 tatccgtcta tagaaacgga gcgtttattg cttagacctg taactttgga tgatgcggaa
    31201 gcaatgtttg actatgcctc ggacaagggt aatacacgtt acacttttcc aaccaatcaa
    31261 agcttggaag aaaccaagaa taacattgct cagttctact tggctaatcc cttgggacgt
    31321 tgggggattg aattaaaaga taacggcaag tttatcggaa ctattgactt acacaagatt
    31381 gatcctgttc ttaagaaggc agctattggc tacattatca ataaaaagta ttggaatcaa
    31441 ggattaacgc cagaaaccaa tcgtgctgtg attgagctag cttttgagaa gataggaatg
    31501 aataagttag ttgctttata cgataaggac aattctgcgt caggaaaggt catggagaaa
    31561 tcaggcatgc gtttttccca tgcagaacca tatgcttgta tggaccagca tgaaaaaggc
    31621 cgaatcgtga caagagttca ttatgtcttg accaaggaag actattttgc aaataaataa
    31681 gcagttgaaa agaaattttt cgactgtttt ttcttcctct tacgaataat ctaagagagg
    31741 agaaaatatg gaagcaatta tcgagaaaat caaagagtat aaaatcatcg tcatctgtac
    31801 tggtctgggc ttgcttgtag gcggattttt cctgctaaag ccagctccac aaacacctgt
    31861 aaaggaaacg aatttgcagg ctgaagttgc agctgtttcc aaggatttgg tatccgaaaa
    31921 ggaagtgaac aaggaagaga aggaagaacc ccttgaacaa gatctaatca cagtagatgt
    31981 caaaggtgct gtcaaatcgc cagggattta tgacttgcct gtaggtagtc gagtcaatga
    32041 tgctgttcag aaggctggtg gcttgacaga gcaagcagac agcaagtcgc tcaatctagc
    32101 tcagaaagtt agtgatgagg ctctggttta cgttcctact aagggagaag aagcagttag
    32161 tcaacagact ggttcgggga cagcttcttc aataagcaag gaaaagaagg tcaatctcaa
    32221 caaggccagt ctggaagaac tcaagcaggt caagggactg ggaggaaaac gagctcagga
    32281 cattatcgac catcgtgagg caaatggcaa gttcaagtca gtagacgagc tcaagaaggt
    32341 ctctggcatt ggtggcaaaa caatagaaaa gcttaaagac tatgttacag tggattaaga
    32401 atttctctat tcccctaatt tacctgagtt ttctattact ttggctttat tacgctattt
    32461 tctcagcatc ttatcttgct ttgttgggct ttgtttttct gctagtctgt ctctttatcc
    32521 aatttccgtg gaaatctgct ggtaaagttc taataatttg cggaatcttt ggattttggt
    32581 ttgtttttca aaattggcaa cagagtcaag cgagtcaaaa tctggcggat tctgttgaaa
    32641 gggtacggat tttgcctgat actattaagg ttaatggtga tagtctatcc tttcgtggca
    32701 agtctaacgg tcgtgctttc caagtctatt ataaactcca gtccgaggag gagaaagaag
    32761 cctttcaagc tttaaccgac ctgcatgaga taggactaga agggaagctt tcggagccag
    32821 aagggcagag aaattttggt ggctttaatt accaagccta tctgaagact cagggaattt
    32881 accagactct caatatcaaa acaatccagt cacttcaaaa gattggcagt tgggatatag
    32941 gagaaaactt gtccagttta cgtcgaaagg ctgtggtttg gattaagacg cactttccag
    33001 accctatgcg caattacatg acaggactct tgctgggaca tctggacacc gactttgagg
    33061 agatgaatga gctttattcc agtctaggaa ttatccacct ctttgcccta tctggtatgc
    33121 aggtaggttt tttcatgaat ggatttaaga aacttctctt gcgattgggc ttgacccaag
    33181 aaaagttgaa atggctgact tatccctttt cccttatcta tgcgggacta actggatttt
    33241 cagcatcggt tattcgcagt ctcttgcaaa agctactggc tcaacatggg gttaagggct
    33301 tggataattt tgccttgacg gtgcttgtcc tctttattgt catgccaaac tttttcttga
    33361 cagcaggagg agtcttgtcc tgcgcttatg cttttatcct gaccatgacc agcaaagaag
    33421 gggaggggct caaggctgtt actagtgaaa gtctagtcat ctccttgggc atattgccca
    33481 ttctatcctt ctattttgcg gaatttcaac ctttgtctat ccttttgacc tttgtctttt
    33541 cctttctatt tgacttgacc ttcttaccgc tcttgtctat tttatttgtc ctttcctttc
    33601 tctatccagt cattcagctg aactttatct ttgaatggtt ggagggcatt attcgcttgg
    33661 tgtcacaggt gacaagtaga cctctggtct ttggacaacc caatgcatgg tttttaatcc
    33721 tattgttaat ttccttggct ttggtctatg atttgagaaa aaacattaaa aagctaacgg
    33781 tattgtgctt attgattaca gggctctttc tcctgaccaa gcatccactg gaaaatgaaa
    33841 tcaccatgct ggatgtgggg caaggagaaa gtattttcct acgggatgta actgggaaaa
    33901 ccattctcat agatgtaggt ggtaaggcag aatcttataa gaaaatcgaa aaatggcaag
    33961 aaaaaatgac gaccagcaat gcccagcgaa ccttgattcc ctatctcaaa agtcgaggag
    34021 tagctaagat tgaccagcta attttgacta acacggacaa ggagcatgtt ggagatttgt
    34081 cagaggtgac caaggctttc catgtagggg agattctagt atcaaaagac agtctgaaac
    34141 agaaggaatt tgtggcagaa ctacaggcga ctcaaacaaa ggtgcgtagt atgacagtag
    34201 gggagaactt gcccattttt ggaagtcagt tagaagttct atctccaagg aaaatgggag
    34261 atggaggaca cgatgatacc ctagttctgt atgggaaatt cttggataag caatttctct
    34321 tcacgggaaa tttggaggag aaaggagaga aggacttgct gaagcactat ccagacttga
    34381 aagtaaatgt tttgaaagct agccaacatg gcaataaaaa atcatcaagt ccagcctttc
    34441 tagaaaaact caaaccagag cttactctta tctcagttgg aaagagcaat cgaatgaaac
    34501 tcccccatca ggaaacattg acacgactgg aaggtatcaa tagcaaagtt tatcgaactg
    34561 accagcaagg agctatacgt tttaaggggt tggatagttg gaaaatcgaa agtgttcgat
    34621 aggaaggata aatgttgtag attagtgaaa taaactaaaa atttgttgca taataatgat
    34681 aaaaatggta taatgaaaac gtattcaata ttgaggatat aaaatcatta aaaattagca
    34741 aaaatcgttt aattagttag tttatgatta ttggtctttt tcagtccagt atatctgctg
    34801 tgacagtcac taaaagttac aagtatgatt ggaatacggt ttgggaatat agtaccaact
    34861 atcacgacca tcagtatgct tggattccgt catggtctcg ttatgacagc tattctgagt
    34921 atccagttgg ttctggctgg aactacggtc gttatgagat cataaactat tacagcggag
    34981 gctattaatt cttaaagagt gagaaaaagg agggctagat atgttgcagc ttactcatgt
    35041 gaccttaaaa acgcgacaag tcatcttgca agatgtggat ttcaccttta aaaagggtag
    35101 ggtttatggt cttcttgcta tcaatggctc tggaaagacg accctgttcc gtgccattag
    35161 caatttaatt cccataagta gtggaaatat cgcagcccct ccttctttat tttattatga
    35221 gagtattgaa tggctggatg gaaacttaag tgggatggac taccttcgtc ttatcaaaaa
    35281 catctggaag tcaggtctga acttgaggga tgaaatcgcc tattgggaaa tgtctgacta
    35341 tatcagtctt cccattcgca agtattcctt aggcatgaag caacgcttgg tgattgccat
    35401 gtatttcctc agtcaggcca aatgctggct catggatgag attacaaatg gcttagatga
    35461 gtattatcga cagaagtttt ttgataggct agcacaaatc gatagacaag aacagctggt
    35521 tcttttaagt tcccactata aggaagagtt ggttgatgtc tgcgatagag tagtaaccat
    35581 tcatcagggg cagatagaag aggtttagtt tatgaaagat gttagtctat ttttattgaa
    35641 aaaagttttc aaaagccgct taaactggat tgtcttagct ttatttgtat ctgtactcgg
    35701 tgttaccttt tatttaaata gtcagactgc aaactcacac agcttggaga gcaggttgga
    35761 aagtcgcatt gcagccaacg agagggctat caatgaaaat gaagagaaac tctcccaaat
    35821 gtctgatacc agctcggagg aataccagtt tgctaaaaat aatttagacg tgcaaaaaaa
    35881 tcttttgacg cgaaagacag aaattctaac tttactaaaa gaagggcgct ggaaagaagc
    35941 ctactatttg cagtggcaag atgaagagaa gaattatgaa tttgtatcaa atgacccgac
    36001 tgctagctct ggcttaaaaa tgggggttga ccgcgaacgg aagatttacc aagccctgta
    36061 tcccttgaac ataaaagcac atactttaga gtttccgacc cacgggattg atcagattgt
    36121 ctggatttta gaggttatca tcccaagctt gtttgtggtt gcgattattt ttatgctaac
    36181 acaactattt gcagaaagat atcaaaatca tctggacaca gctcacttat atcctgtttc
    36241 aaaagtgaca tttgcaatat cctctcttgg agttggagtg ggatatgtaa ctgtgctgtt
    36301 tatcggaatc tgtggctttt cttttctagt gggaagtctg ataagtggtt ttggacagtt
    36361 agattatccc tacccgattt atagcttagt gaatcaagag gtaactattg gaaagatgca
    36421 ggatgtatta tttcctggct tgctcttagc tttcttagcc tttatcgtca ttgtggaagt
    36481 tgtgtatttg attgcttact ttttcaagca aaaaatgcct gtcctctttc tttcactcat
    36541 tgggattgtt ggcttattgt ttggcatcca aaccattcag cctcttcaaa agattgcaca
    36601 tctgattccc tttacttact tgcgttcagt ggagatttta tctggaagat tacctaagca
    36661 gattgataat gtcgatctaa attggagcat ggggatggtc ttacttcctt gcctgattat
    36721 ccttttgtta gtggggattc tatttatcga aagatgggga agttcacgta aaaaggaagt
    36781 ttttaaagtt tagttttcct atagggaagc taaagaaaaa ctaacatagg gagagaatca
    36841 acttggttct ctctttttga ttcgaaaacc aaaccaaaat acaaacacaa acttttcaaa
    36901 aaataacttt ttatcttgac aagagctaga aaacttggta tcatataaaa gttgagaaaa
    36961 gcagaagtga gagcttctcg ccttgtgaca ttaagttgcc tggccctacg gatgaaaagt
    37021 ttcgaagaaa cgctatcata acgtgcgggc ttgtatattt acgagtccgc tattgttttt
    37081 ctctaataaa acaaaagagg tgaaaaccat agcaaagcaa gacttattca tcaatgatga
    37141 gattcgtgta cgtgaagttc gcttgattgg tcttgaggga gaacagctag gcatcaagcc
    37201 actcagtgaa gcgcaagctt tggctgataa cgctaatgtt gacctagtat tgattcaacc
    37261 ccaagccaaa ccgcctgttg caaaaattat ggactacggt aagttcaaat ttgagtacca
    37321 gaagaagcaa aaagaacaac gtaaaaaaca aagcgttgtt actgtgaaag aagttcgtct
    37381 aagtccaaca attgacaagg gtgactttga tacaaaactt cgtaatgcac gtaagttcct
    37441 tgaaaaagga aataaagtta aggtatctat tcgctttaag ggtcgtatga ttacccataa
    37501 agagattggt gcaaaagttt tagccgagtt tgctgaagca actcaagata ttgccatcat
    37561 cgaacaacgt gctaaaatgg atggacgtca aatgttcatg caattggcgc cagcgactga
    37621 caaaaaataa ttgtcagaaa gttaaataaa ggagaaaaaa tcatgccaaa acaaaaaaca
    37681 caccgcgcat cagctaaacg tttcaaacgt acaggttctg gtggacttaa acgtttccgt
    37741 gcttacactt ctcaccgttt ccacggaaaa actaagaaac aacgtcgtca tcttcgtaaa
    37801 gcatctatgg tgcattcagg agattacaaa cgtatcaaag caatgcttac tcgcttgaaa
    37861 taatagcttg actgtaagta aacaattcta gaaaatattt ggaggaaata aaacatggca
    37921 cgtgttaaag gtggcgttgt atcacgcaaa cgtcgtaaac gtattcttaa attagcaaaa
    37981 ggttactatg gagctaaaca catcttgttc cgtactgcaa aagaacaagt aatgaactct
    38041 tactactatg cataccgtga ccgtcgtcag aaaaaacgtg acttccgcaa attgtggatt
    38101 actcgtatca atgcggcggc tcgtatgaac ggactttcat actcacaatt gatgcatggt
    38161 ttgaaattgg ctgagatcga agttaaccgt aaaatgcttg ctgacttggc tgttaacgat
    38221 gcagtagctt tcacagctct tgcagatgca gctaaagcaa aacttggtaa ataacaactg
    38281 atgagactgg aacaggattg tccagtcttt ttaaaaataa aggagaaaga tatggcttca
    38341 aaaatgctac acacttgctt acgagtagaa aatcttgaaa aatcaatcgc attttatcaa
    38401 gatgcttttg gttttaaaga attgcgtcgc agagattttc cagaccatgc cttcacgatt
    38461 gtctatctag gtcttgaggg tgatgattat gagttggagt tgacttataa ctacgatcac
    38521 ggtccgtatg tggttggtga tgggtttgcc catatcgccc tcagtacacc tgatcttgag
    38581 gcacttcatc aagaacacag tgcaaaaggc tatgaagtga ctgagccaaa tggtctacca
    38641 ggaactacac caaactatta ctttgttaaa gaccctgatg gatataaggt cgaagtcatt
    38701 cgtgaaaaat aatttcgtgc aagttaagta gaatattcgt tttctacttg acttttttta
    38761 gctgaaagag tatactaata aaaattcaac ctttaagggg agtccagaga gactcacaag
    38821 gtgtcagata aaagaatagt gcaagtttct agaggagacc ttttgagtgt gctctcttgt
    38881 gttgtacgat tttaactgag gccttgcact agcaaggtct tttctttatc tggtcccctt
    38941 aaaatttaag gaggaaaagt tatgaatctc acatgtaaga agcgtttggg tgtcattcgg
    39001 ttggaaacca tgaaggtggt tgcacaagag gaaatcgcgc cagcaatctt tgaattagtc
    39061 ctagaaggag aaatggttga agccatgcga gcaggccaat ttcttcatct gcgtgtacca
    39121 gacgatgccc atctcttacg tcgtcctatt tcaatttcgt ctattgacaa ggcaaacaag
    39181 cagtgtcacc tcatttatcg gattgaggga gctgggactg caattttttc aaccttaagt
    39241 cagggagaca ctcttgatgt gatggggcct cagggaaatg gttttgactt gtctgacctt
    39301 gatgagcaga atcaggttct ccttgttggt ggtgggattg gtgttccacc cttgcttgag
    39361 gtggccaagg aattgcatga acgtggagtg aaagtagtga cagtcctcgg ttttgctaat
    39421 aaggatgctg ttattttgaa aacggaattg gctcagtatg gtcaggtctt tgtaacgaca
    39481 gatgatggtt cttatggcat caagggaaat gtttccgttg ttatcaatga tttagacagt
    39541 cagtttgatg ctgtttactc gtgtggggct ccaggaatga tgaagtatat caatcaaacc
    39601 tttgatgatc acccaagagc ctatttatct ctggaatctc gtatggcttg tgggatggga
    39661 gcttgctatg cctgtgttct aaaagtacca gaaagcgaga cggtcagcca acgcgtctgt
    39721 gaagatggtc ctgttttccg cacaggaaca gttgtattat aaggagaaaa ttatgactac
    39781 aaatcgatta caagtttctc tacctggttt ggatttgaaa aatccgatta ttccagcatc
    39841 aggctgtttt ggctttggac aagagtatgc caagtactat gatttagacc ttttaggttc
    39901 tattatgatc aaggcgacaa cccttgaacc acgttttgga aatccaactc caagagtggc
    39961 agagacgcct gctggtatgc tcaatgcaat tggcttgcaa aatcctggtt tagaggttgt
    40021 tttggctgaa aagctacctt ggctggaaag agaatatcca aatcttccta ttattgccaa
    40081 tgtagctggt ttttcaaaac aagagtatgc agctgtttct catgggattt ccaaggtaac
    40141 taatgtaaaa gctatcgagc tcaatatttc ttgtcccaat gttgaccact gtaatcatgg
    40201 acttttgatt ggtcaagatc cagatttggc ttatgatgtg gtgaaagcag ctgtggaagc
    40261 ctcagaagtg ccagtttatg tcaaattaac cccgagtgtg accgatatcg ttactgtcgc
    40321 aaaagctgca gaagatgcgg gagcaagtgg cttgaccatg atcaatactc tggttggaat
    40381 gcgctttgac ctcaaaacca gaaaaccaat cttggccaat ggaacaggtg gaatgtcagg
    40441 tccagcagtc tttccagtag ccctcaaact catccgccaa gtagcccaaa caacagacct
    40501 gcctatcatt ggaatggggg gagtggattc ggctgaagct gccctagaaa tgtatctggc
    40561 tggggcatct gctatcggag ttggaacagc taactttacc aatccttatg cctgccctga
    40621 catcatcgaa aatttaccaa aagtcatgga taaatacggt attagcagtc tggaagaact
    40681 ccgtcaggaa gtaaaagagt ctctgaggta aactgcaatc aatctgttct tgatttttta
    40741 ttagtttgta atatgaattt aggagaattt tggtacaata aaataaataa gaacagagga
    40801 agaaggttaa tgaagaaagt aagatttatt tttttagctc tgctattttt cttagctagt
    40861 ccagagggtg caatggctag tgatggtact tggcaaggaa aacagtatct gaaagaagat
    40921 ggcagtcaag cagcgaatga gtgggttttt gatactcatt atcaatcttg gttctatata
    40981 aaagcagatg ctaactatgc tgaaaatgaa tggctaaagc aaggtgacga ctatttttac
    41041 ctcaaatctg gtggctatat ggccaaatca gaatgggtag aagacaaggg agccttttat
    41101 tatcttgacc aagatggaaa gatgaaaaga aatgcttggg taggaacttc ctatgttggt
    41161 gcaacaggtg ccaaagtaat agaagactgg gtctatgatt ctcaatacga tgcttggttt
    41221 tatatcaaag cagatggaca gcacgcagag aaagaatggc tccaaattaa agggaaggac
    41281 tattatttca aatccggtgg ttatctactg acaagtcagt ggattaatca agcttatgtg
    41341 aatgctagtg gtgccaaagt acagcaaggt tggctttttg acaaacaata ccaatcttgg
    41401 ttttacatca aagaaaatgg aaactatgct gataaagaat ggattttcga gaatggtcac
    41461 tattattatc taaaatccgg tggctacatg gcagccaatg aatggatttg ggataaggaa
    41521 tcttggtttt acctcaagtt tgatgggaaa atagctgaaa aagaatgggt ctacgattct
    41581 catagtcaag cttggtacta cttcaaatcc ggtggttaca tgacagccaa tgaatggatt
    41641 tgggataagg aatcttggtt ttacctcaag tctgatggca aaatggctga aaaagaatg
//
LOCUS       DAVLAQ010000011        41407 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000011 DAVLAQ010000000
VERSION     DAVLAQ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41407
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.011"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..3058
                     /locus_tag="VXB71_000584"
     CDS             <1..3058
                     /locus_tag="VXB71_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0450741.1"
                     /translation="NQGKDGDKYVNTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAK
                     GEKGDRGERGLTGAQGAKGADGAAGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVNT
                     ETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGK
                     DPVTVNVKDGENGLNGKTPKVDLLRVQGQNGNPPHTIVTFYTDENNDGKYTPGTDELL
                     GSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDG
                     KSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITTQ
                     RGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAAT
                     PTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHT
                     ITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDG
                     KTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITN
                     PDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKV
                     TITDEQNGTHKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSET
                     TVRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKV
                     TGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSP
                     TVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDG
                     TVTKTVIKDGKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPE
                     VPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNA
                     NPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(3295..3843)
                     /locus_tag="VXB71_000585"
     CDS             complement(3295..3843)
                     /locus_tag="VXB71_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0450742.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            4164..4652
                     /locus_tag="VXB71_000586"
     CDS             4164..4652
                     /locus_tag="VXB71_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0450743.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            4649..5836
                     /locus_tag="VXB71_000587"
     CDS             4649..5836
                     /locus_tag="VXB71_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0450744.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            5829..6194
                     /locus_tag="VXB71_000588"
     CDS             5829..6194
                     /locus_tag="VXB71_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0450745.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            6210..7556
                     /gene="asnS"
                     /locus_tag="VXB71_000589"
     CDS             6210..7556
                     /gene="asnS"
                     /locus_tag="VXB71_000589"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0450746.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            7709..7999
                     /locus_tag="VXB71_000590"
     CDS             7709..7999
                     /locus_tag="VXB71_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0450747.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            8011..8481
                     /gene="ssbA"
                     /locus_tag="VXB71_000591"
     CDS             8011..8481
                     /gene="ssbA"
                     /locus_tag="VXB71_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0450748.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            8513..8752
                     /locus_tag="VXB71_000592"
     CDS             8513..8752
                     /locus_tag="VXB71_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0450749.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            9047..10447
                     /locus_tag="VXB71_000593"
     CDS             9047..10447
                     /locus_tag="VXB71_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0450750.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            10449..10808
                     /locus_tag="VXB71_000594"
     CDS             10449..10808
                     /locus_tag="VXB71_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0450751.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            10862..11611
                     /locus_tag="VXB71_000595"
     CDS             10862..11611
                     /locus_tag="VXB71_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0450752.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            11601..11900
                     /locus_tag="VXB71_000596"
     CDS             11601..11900
                     /locus_tag="VXB71_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0450753.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            11971..12906
                     /locus_tag="VXB71_000597"
     CDS             11971..12906
                     /locus_tag="VXB71_000597"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0450754.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            12992..13504
                     /locus_tag="VXB71_000598"
     CDS             12992..13504
                     /locus_tag="VXB71_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0450755.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            13529..14137
                     /locus_tag="VXB71_000599"
     CDS             13529..14137
                     /locus_tag="VXB71_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0450756.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            14238..14435
                     /locus_tag="VXB71_000600"
     CDS             14238..14435
                     /locus_tag="VXB71_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0450757.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(14478..15923)
                     /locus_tag="VXB71_000601"
     CDS             complement(14478..15923)
                     /locus_tag="VXB71_000601"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0450758.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVKDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            16029..17651
                     /locus_tag="VXB71_000602"
     CDS             16029..17651
                     /locus_tag="VXB71_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0450759.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLCSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            17855..19813
                     /locus_tag="VXB71_000603"
     CDS             17855..19813
                     /locus_tag="VXB71_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0450760.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSVQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            19985..20218
                     /locus_tag="VXB71_000604"
     CDS             19985..20218
                     /locus_tag="VXB71_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEV0450761.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            20224..21666
                     /locus_tag="VXB71_000605"
     CDS             20224..21666
                     /locus_tag="VXB71_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450762.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARA
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            21824..22918
                     /locus_tag="VXB71_000606"
     CDS             21824..22918
                     /locus_tag="VXB71_000606"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0450763.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            22926..24092
                     /locus_tag="VXB71_000607"
     CDS             22926..24092
                     /locus_tag="VXB71_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0450764.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            24185..27283
                     /locus_tag="VXB71_000608"
     CDS             24185..27283
                     /locus_tag="VXB71_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0450765.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            27331..27948
                     /locus_tag="VXB71_000609"
     CDS             27331..27948
                     /locus_tag="VXB71_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0450766.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            27959..29293
                     /locus_tag="VXB71_000610"
     CDS             27959..29293
                     /locus_tag="VXB71_000610"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0450767.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            29303..29767
                     /locus_tag="VXB71_000611"
     CDS             29303..29767
                     /locus_tag="VXB71_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450768.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            29764..30258
                     /locus_tag="VXB71_000612"
     CDS             29764..30258
                     /locus_tag="VXB71_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450769.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            30339..31994
                     /gene="mltG"
                     /locus_tag="VXB71_000613"
     CDS             30339..31994
                     /gene="mltG"
                     /locus_tag="VXB71_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0450770.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            32065..32547
                     /gene="greA"
                     /locus_tag="VXB71_000614"
     CDS             32065..32547
                     /gene="greA"
                     /locus_tag="VXB71_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0450771.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            33055..33453
                     /locus_tag="VXB71_000615"
     CDS             33055..33453
                     /locus_tag="VXB71_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0450772.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            33898..34905
                     /locus_tag="VXB71_000616"
     CDS             33898..34905
                     /locus_tag="VXB71_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0450773.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            34980..35180
                     /locus_tag="VXB71_000617"
     CDS             34980..35180
                     /locus_tag="VXB71_000617"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0450774.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            35215..35931
                     /gene="atpB"
                     /locus_tag="VXB71_000618"
     CDS             35215..35931
                     /gene="atpB"
                     /locus_tag="VXB71_000618"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0450775.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            35945..36439
                     /gene="atpF"
                     /locus_tag="VXB71_000619"
     CDS             35945..36439
                     /gene="atpF"
                     /locus_tag="VXB71_000619"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0450776.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            36439..36975
                     /locus_tag="VXB71_000620"
     CDS             36439..36975
                     /locus_tag="VXB71_000620"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0450777.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            36990..38495
                     /locus_tag="VXB71_000621"
     CDS             36990..38495
                     /locus_tag="VXB71_000621"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0450778.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            38511..39389
                     /locus_tag="VXB71_000622"
     CDS             38511..39389
                     /locus_tag="VXB71_000622"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0450779.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            39475..40881
                     /gene="atpD"
                     /locus_tag="VXB71_000623"
     CDS             39475..40881
                     /gene="atpD"
                     /locus_tag="VXB71_000623"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0450780.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            40892..41311
                     /locus_tag="VXB71_000624"
     CDS             40892..41311
                     /locus_tag="VXB71_000624"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0450781.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT        12731 a         7713 c         9235 g        11728 t
ORIGIN      
        1 aaatcaaggt aaagacggcg ataaatacgt taatacagaa acaggtgatg tctatgttaa
       61 aaacaatgga aactgggata aagagggcaa catcaaagga cctaaaggtg acaaaggtgc
      121 agatggtgcc aaaggcgaaa aaggagaccg aggcgaacgc ggcctgactg gagcgcaagg
      181 agctaaaggt gcggatggag cagcaggtcg tgacggacgt gatggacgtg acggtaaaga
      241 cgtgttgaac ggcaaagtta acccagaagc aaatcaaggt aaagacggtg ataaatacgt
      301 caatacagaa acaggcgacg tcttcgttaa gaataacggc aactgggata aagagggcaa
      361 catcaaggga cctaaagggg acaaaggtga acgcggagaa gatggtaaga ctccagaagt
      421 aactgtaact ccaggtaaag atggccatag tactgacatt acattcactg ttccaggtaa
      481 agatccagtt acagtaaatg ttaaggacgg agaaaatggt ctgaacggta aaactccaaa
      541 agttgattta cttcgtgtcc aaggacaaaa cggaaatcca cctcatacaa ttgtgacatt
      601 ctatacagat gaaaacaatg atggcaaata tacaccagga actgatgaac ttctaggttc
      661 agaaatgatt aaagatggtg ctaaaggtgc ggacggacga gatggtaaat cattgcttac
      721 tgtcaaggat ggtaaagaaa ctaaagttta ccaagaagat ccagctaacc caggacaacc
      781 attaaatcca gaaaaaccac ttgcggtaat tagagatgga gtagatggaa aatcacctac
      841 agttacagct gttcgtaaag atgaagcagg gcataaaggt gtagaaatca ctgttgataa
      901 ccatgatggt tcacaaccaa ctacagtctt tgttcaagat ggtgctaagg gagaaactgg
      961 tgcaaccggt caagatggac aaactcctac aatcactact caacgtggac aagatggcca
     1021 aagcactgtt gtaactatca caacatcagg taaagatcca gtaaccttca ctgtaaaaga
     1081 tggtaagaat ggtaaagatg gccgtgcacc gaaaatcaaa gtagaagata ttacttcacc
     1141 ttcaagaatt agacgcgata cagatgctgc tgcaactcca acgcgtaacg gtatccgtgt
     1201 tacagtttat gatgatgtta atgacaatgg ggtatacgac gaaggtgtcg ataaagtatt
     1261 aaatagtaaa gatatttata acggtataga tggacgtgat ggttcagctc caactattac
     1321 tacaaaagat aatggagatg gaactcacac tatcacagtt caaaacccag atggttctga
     1381 atcaacaaca gttgttaaag atggtaaaga cggtaaaact gcgaatatca ctacaacaga
     1441 aaacccagat ggaagccaca caattacggt gacaaatcca gatggttcaa ctaaagaaac
     1501 tgttgttaaa aacggtaaag acggtaagac tcctaaagtt gaagtaacgg ataacaacga
     1561 tggaactcat actgttaaag ttacagatgg agacggcaat gttaccaacg ctatcatcaa
     1621 agatggtaaa gacggtaaag ctgcaacagc aacaactact gaaaatccag atggaagcca
     1681 cacagtaaca atcactaacc cagacggaac taagaatgag tttgttgtta agaatggacg
     1741 tgacggtgtt gacggacgta ctccaaccgc atctgttcgt gataatggag acggaagtca
     1801 tacaatcgtt attacaaatc cagaaggtgt gacaactgaa accacagttc gtgatggtaa
     1861 atcaccaaaa gtgactataa ctgatgaaca aaatggaact cataagatct ctgttctaaa
     1921 tggtgacgga acaactactg aaacaatcat taaagatggt aaatcaccag tagcaacagt
     1981 tagagataac caagatggta cttacactat tcgtgtggaa aacggtaatg gtactgtttc
     2041 tgaaaccaca gttcgtgacg gtaaatcacc aactgctaag gttgtggata atggagatgg
     2101 aactcacact atcacagttg tgaactcaga cggaacaact acaacaacta cagttcgtga
     2161 tggtagagaa ccaaaacttg aagttattga taacaacgat ggttcacaca ctattaaagt
     2221 gacaggtgct gatggtaaag gaacgacaac tacaatcttt gatggtaaat caccaaaagc
     2281 gaacatcgtt gataacggag atggaactca tacattaaca atcgtagatt ctgatggtcg
     2341 tgaatacaaa tctattatca aagatggtaa agacggcaaa gatagcgttt caccaactgt
     2401 aactgttaaa aataataacg atggaactca cgttgttaca atcactaatc cagatggaag
     2461 taagacagaa atggtgatta aagacggtaa agatggtaaa tcaccaaaag tttctgttga
     2521 agataatggt gatggtagtc atacaatcac aatcatcaat tctgatggaa ctgtgacaaa
     2581 aacagttatt aaagatggca aagatggtag agatggacgt gatggtcgag acggcaaaga
     2641 cggtaaagac ggtaaagatg gaaaatgtgg atgccaagac aaaccagtaa caccatcaaa
     2701 tgacaaacca gttcctccaa caccaaatgt gccgacacca gaagtaccgg ttaaacctgt
     2761 gccagcgcaa ccaacaccaa atgtaccgac accagaagtg ccagtacaac caactccagc
     2821 tgttccaaca ccagaagtac cggttaaacc agtaccagcg gttccagaac aaccagtagt
     2881 accaacaccg gctcaaccag caactccagt aaatgctaat ccagtagcac caactacagg
     2941 taaagaaaac cgtggggaca aattacctga aactggaagc caatctgatt atatctctgt
     3001 tcttttaggt agcggtattc tattgagcct atatgtagga cgaagaaaag aagattaatc
     3061 agccaaaagc agtcactaat ttctcgaaag aagatgataa gtgatagatc tcgaatgaaa
     3121 gaatattctt agaatgattt tcctatgatg gaaaagactg ctaaaaacct tgagtggtaa
     3181 cgctcaaggt ttttttggat ggctgatgtt tgtctgaaaa tcttgattga gaaataaaaa
     3241 gccaccctat taggtggcta taattgattt agactttcta aaattttcta ttttttactg
     3301 aatcgcttcg accaagtctt gagcttgttt ttcaagtgag tttaggactg tttcttcaag
     3361 aaccaatttt ccgtctgccc aggcagagtc attaacacgt gcagcagtga aatcaccaac
     3421 gccttgtgta cggataaatg gcaagaggtc tttgtagata gcgaaaagtt gatcgtgccc
     3481 tgcattggct acagatgata ctgtgacaaa cttgtcttga agggcagaaa cgccacgtgt
     3541 atcagacaag tcaagggcac gagatagcca gtcaagcaag tttttcactg taccagggat
     3601 agagaagttg tagactggag agaaaatcca gatagcatcc gcaacgagaa ctgcttcacg
     3661 agcagcagct acagctggat gtgttggaac ttccaaatct tggctgaaga gaggaagggc
     3721 tgaataatca aggtagctaa cttccgcttt accagcaagt gctttctcag cttcgagcgc
     3781 catttggtgg ttgaaagaac cttgacgtag tgatccgacg ataaataata cttttttaga
     3841 catgatgtgt ctcctttttc ttaaaatttc gagaactctc tcgttgttat aaaatatatt
     3901 acaacaaaac aaaagaactt gcaagaaatt tgctcagagt ttatttgaaa attgtaaaat
     3961 ttcggaaact ctaatcattt gtgactgaaa aagtaagaac tgtttcactt tcaaaatcgg
     4021 ttttgtttga agggagaaat agaattggtt gctcaaagca cagctttgag gttgcagata
     4081 aagctgacgt ggtttgaaga gattttcgaa gagtattctt atattcactt gtaataaagc
     4141 ttaatagatg gtaaaataga cgagtgaaaa aaagacaaaa caaagcaaaa aataatctac
     4201 tgtggcagta tggtctaggg atgacgattt tgtttgtggt tatcagtggt tcctttctgt
     4261 atatggtttc tcttagcatg aaaccctatc aaacagctaa aagtgaagga gaaaaattag
     4321 ctcagcagta tgcaggatta gagcaggtcg atcaggttga tttatacaat ggcttggaat
     4381 cttattacag cgttcttggt cgtaataaac agcaagaagc gcttgctgtc ctgattggta
     4441 aagatgacca taagatttac gtttatcagc taaatcaggg tgtttcacaa gaaaaagcag
     4501 aaacggtttc taaggaaaag ggagctggcg agattgacaa gataaccttt ggccgttatc
     4561 aagataagcc aatctgggaa gttaagtcag gatctgattt ttatctagta gattttgaaa
     4621 caggagcatt ggtcaacaag gagggcctat gaaactatcc aaccgtgttt tagaaatgga
     4681 agaaagtgtg actttggctg ctggagcccg tgccaaagca ctgaaggctg agggtagaga
     4741 tattttgtct ctaaccttgg gtgagccaga tttcactact cccaaaaata tccaagatgc
     4801 cgccattgca tcgattcgag atgggcgtgc ttctttttat acagtaacct caggtctgcc
     4861 agagcttaag gcggcggtca atagctactt tgagcgcttt tacggctatt ctgtagcgtc
     4921 aaatcaagtg acagtcgctg cgggagccaa atattctctc tataccttct ttatggctgt
     4981 ggtcaatcca ggtgatgaag tcatcatccc aaccccatac tgggttagct atggagatca
     5041 ggtcaagatg gcagaaggcg ttcccgtctt tgtttctact aaggaagaca atcactttaa
     5101 ggtgaccgta gatcagttag aagcagctcg cactgacaag accaaggttt tggtgctgaa
     5161 ttcgccatct aatcccacag gtatgattta cacccgtgag gaactcttgg caattggaaa
     5221 ctgggctgta gaaaatgata ttctcatcct agcagatgat atctatggcc gcttggttta
     5281 taatggtcat gagttcacac cgatttctag cctatcggaa gcgattcgca agcaaacagt
     5341 ggtcatcaat ggtgtgtcta aaacctatgc catgactggt tggcggattg gttatgccgt
     5401 tggagaagca gatattatcg ctgccatgtc caagattgca ggtcaaacaa cttcgaatcc
     5461 gtcagcagta gcccaatatg cagcagttga ggctctatca ggtgagcaag atactgtaga
     5521 aagcatgcgt caggcctttg aggaacgtct taataccatc tatcccctcc ttgcagaggt
     5581 accaggattt gaagtggtca aaccgcaagg ggccttctat ctcttcccaa atgtcaaaaa
     5641 ggccatggag atgaaaggct acacggatgt gacagacttt acaactgcta tcttagaaga
     5701 agccgaagtg gccttggtaa caggagctgg atttggagca ccagaaaatg tccgcctcag
     5761 ctatgcgaca gacctagaca cgcttaaaga agcagtcgaa cgcttgaaag catttatggg
     5821 tagtgagaat gattgatcat tttgagatta aggtaaagga tttacaaatt tcagaaggat
     5881 tttataggag ttttctcgct cctttggact ataaattggc ttttaagact agttctctaa
     5941 ttagttttct atccccgaac agccctcatc ctggtggtga tttttggctg actcagggaa
     6001 cacaagatcc tgttcatttt gcttttttag cagaaaataa ggaagaagtt caggcttgtt
     6061 atgaggctgg cttagaggca ggtgggcgag acaatggggc tcctggttat cgaagtgagc
     6121 atccgattta ctatgctgct tttatgattg acctggatgg gaacaatata gaggtggttt
     6181 gccataaaga ataaaaaaga aaaggaaaaa taatgacaaa acgtgtaacg attattgacg
     6241 taaaagacta tgttggtcag gaagtgacga ttggcgcttg ggttgccaac aaatcaggaa
     6301 aaggaaaaat cgctttctta caattgcgtg atggaacagc cttctttcaa ggtgtggctt
     6361 ttaaaccaaa ctttgtcgaa aaatttggtg aagaagtggg acttgagaag tttgatgtta
     6421 tcaaacgctt gagccaagaa acgtctgttt atgtgacagg tattgtcaaa gaggacgaac
     6481 gttctaaatt tggctatgag ttggacatca cagacatcga agtgatcggt gaatctcaag
     6541 actacccaat cacaccaaaa gaacacggaa cagacttttt gatggataac cgtcacttgt
     6601 ggctacgctc tcgtaagcaa gtagctgtgt tgcaaatccg taacgctatt atctatgcaa
     6661 cttatgagtt ctttgacaag aacggtttta tgaagtttga cagcccaatt ctttcaggaa
     6721 atgcggcaga agattctaca gaactctttg aaactgacta cttcggaacg ccagcctact
     6781 tgagccaatc aggtcagctt tacctagaag caggggctat ggctcttggt cgtgtctttg
     6841 actttggtcc agttttccgt gctgaaaaat caaaaacacg ccgtcacttg actgagttct
     6901 ggatgatgga tgctgagtac tcatacttga cacatgatga gtcgcttgac ttgcaagaag
     6961 cttatgtgaa agctcttcta caaggtgttc ttgaccgcgc gcctcaagcc ttggaaacct
     7021 tggaacgtga tacagaactc ttgaaacgct acattgcaga gccattcaaa cgtatcactt
     7081 acgatcaagc cattgacctc ttgcaagagc atgaaaatga tgaagatgct gactacgagc
     7141 atcttgagca tggtgatgac tttgggtcac cacacgaaac ttggatttca aaccactttg
     7201 gtgtgccaac atttgtcatg aactatccag cagccatcaa ggccttctac atgaaaccag
     7261 ttcctggaaa tccagagcgc gtgctttgtg cagacttgct tgctccagaa ggctatggag
     7321 aaattatcgg tgggtctatg cgtgaggaag attacgatgc ccttgtcgct aagatggatg
     7381 aacttggcat ggatcgtaca gaatatgaat tctaccttga ccttcgtaaa tacggtacag
     7441 ttccacacgg aggatttggt atcggtatcg aacgtatggt aaccttcgca gcaggaacaa
     7501 aacatatccg tgaagctatt ccattcccac gtatgttgca ccgtatcaaa ccataagaac
     7561 aggaaaacgc ccatgtggcg ttttttcgaa ttctagtgtt tttacttgcg taaaaaaatt
     7621 ttttctagta taatagttta ttgtgagcga acctcactta ccccttgcaa agtcttgggg
     7681 tcattagacc aaaaggagga acatatcaat ggctaaatac gaaattcttt atatcattcg
     7741 tccaaacatt gaagaagaag ctaaaaacgc tttggtagca cgttttgact ctattttgac
     7801 tgacaacggt gcaactgttg ttgaatcaaa aacttgggaa aaacgtcgtc ttgcatacga
     7861 aatccaagat ttccgtgaag gactttacca catcgttaac gttgaagcaa atgacgatgc
     7921 agctcttaaa gagtttgacc gtctttcaaa aatcaacgct gacattcttc gtcacatgat
     7981 cgtcaaaatt gacgcgtaag aaggtaaact atgattaaca atgttgtact tgtagggcgt
     8041 atgacacgtg acgctgagtt gcgttatacc ccatcaaatg tagcagttgc gacttttact
     8101 cttgcagtaa accgtacatt taagagtcaa aatggtgaac gtgaggctga ttttatcaat
     8161 gtcgttatgt ggcgccaaca ggctgaaaat cttgctaact gggctaaaaa aggctcactt
     8221 atcggggtga caggtcgtat ccagactcgt agttacgata accagcaagg acaacgtgtc
     8281 tacgtgacag aggtcgtggc tgagaatttc caaatgttgg aaagccgtag tgtgcgtgag
     8341 ggccacacag gtggagctta ctctgcacca actgcaaact attcagcacc tacaaattca
     8401 gtaccagact tttcacgtaa tgaaaatcca tttggagcaa caaacccatt ggatatttca
     8461 gatgatgatt taccattcta atggacaact aaacttataa aggagaaaaa acatggctca
     8521 acaacgtcgt ggcggattca aacgccgtaa aaaagttgat tacatcgcag caaacaaaat
     8581 tgaatatgtt gattacaaag atactgagct tcttagccgt ttcgtttcag aacgtgggaa
     8641 aatccttcct cgtcgtgtaa caggaacttc agctaaaaac caacgtaaag taacaacagc
     8701 tatcaaacgc gctcgcgtaa tggctttgat gcctttcgta aacgaagatt aaagaaaaga
     8761 cccggttggg tctctttttc atgagcttga aaacaagaaa gcgaattaag accccaacgg
     8821 gtcttttttc acaagctttg aaatgagaga gcgagttagg ctcagtggct ccctttttac
     8881 gagtttgaaa acaagagaac acattaaaag cacgatggag ctttttcata aatatgtctt
     8941 ttttctcatc caagaaatta aaataaaaat gataaacttt ttgaaaatag gggatttgcc
     9001 tactttatga tataatggaa agagttagat tgaaagaggt agtgagatgg acgcgaaatt
     9061 aagatacaag gcaaagaaga tcaagattgt cttttttgat attgatgata cattgcggaa
     9121 ttcaaagaca gggtttattc caactacaat tcccactgtt tttaaacagt tgcgtgaaaa
     9181 aggaatttta acaggaatcg cctctggacg tggcattttt ggtgttgttc cagagattcg
     9241 tgatctcaag cctgactttt ttgtaacttt gaatggagct tatatcgaag ataaaaaagg
     9301 tcaggtcatt tatcagcatc agattgaaaa gtcagatgtt gaggagtata tctcttgggc
     9361 taagcaagaa ggaattgagt atggcttggt tgggagtcat gatgccaagt tgtcgactcg
     9421 caccgatatg atgagtgaag ctatcaatcc aatttatccc gacttagatg tagatcccga
     9481 tttccatgaa aaagaagata tctatcagat gtggactttt gaagataagg gagatgactt
     9541 gcacttgcct gacagtctct cagacaaact tcgcatggtt cgttggcatc aacattcgtc
     9601 tgatattgtg ccgatttcag gctccaaagc gacgggggtg gaaaaggttg tggaacacct
     9661 tggcttgaaa ccagagaagg tcatggtttt tggagatggt ctcaacgact tggaactctt
     9721 tgattatgct ggaatcagcg ttgccatggg aatttctcat gataaaatca aagaaaaagc
     9781 agattatatt acaaaaacat tagaagaaga tggcattttt gatgccttag aagtatttgg
     9841 tatggtagaa aaagaattgc attttccaca agtagacatt gaaacagtag aaggtcctct
     9901 tgcgactatt aagaccaatc acggagactt acgtatcaag cttttccctg aacatgctcc
     9961 taaaacagtg gctaactttg tatctctttc aaaagatggc tactatgatg gtgtcatttt
    10021 ccaccgtatt atcaaggact ttatgatcca aggtggagac ccaactggaa ctggtatggg
    10081 tggcgagtca atctacggcg aatcttttga ggatgaattc tcagaagagc tttacaatat
    10141 ccgtggtgct ctttccatgg caaatgctgg tccaaatacc aacggcagcc agttctttat
    10201 cgtgcaaaac caacacctac cttattcgaa gaaagaaatt actcgtggtg gttggccaga
    10261 accgattgca gaaatctatg ccaatcaagg tgggacacct cacctagacc gccgtcacac
    10321 ggtttttggt cagttagctg atgaagcatc ttacgctgtc ttggatgcca ttgctgctgt
    10381 tgagacagga gctatggaca agccagttga agatgttgta attgaaacta ttgaaatcga
    10441 ggactaagat gaaaatcggt gataagctaa aggggcgtat tacagggatt cagccctacg
    10501 gtgcctttgt tgagttagag acgggtgata cggggctgat tcacatttca gaaattcgga
    10561 caggatttat tgaaaatatt catgaaacct tgaaagtcga tgaagaggtt caagttcagg
    10621 tagtggattt agatgaattt acggggaaag ccagtctttc tatccgcact ttggaggaag
    10681 aaaagtacca gtttcctaga cggagacgct tttcaagcga ccgctttaac tacggttttg
    10741 ctccctttcg acgaatgcta ccaatctgga ctggagaagc cctgcaccat ttaaaaaaga
    10801 agaagtagtt tagagtttta tattttttgt aatgttaata tgaatttgct ataataggac
    10861 catggaagaa gaacaattat taaaatcagg agagcgcatt aaccagctct tttcgacaga
    10921 tatcaaaatc attcaaaata gagaggtttt tagctattcg gtggatagtg ttctcttatc
    10981 acgatttcca cgttttccta agaaggggtt gattgtggat ttctgtgctg ggaatggagc
    11041 agtggggctt tttgctagca ctcgtactca agcacagata ttgtctgttg agattcagga
    11101 gcgtttggcg gatatggctg aacgctctgt ccgtttgaat ggattagagg agcaaatgca
    11161 ggtcatctgc gatgatttga aaaatatgcc tgctcacatt caggggagta aggtggatat
    11221 gattttgtgt aatccaccct atttcaaggt gaatccttat tctaatctga acgagagtga
    11281 acattatctc ttggctcgac acgaaatcac gactaatttg gaagaaatct gtcgtagtgc
    11341 ccagagtatt ctcaagtcta atgggcgttt ggccatggtt catcgtcctg atcgacttct
    11401 ggatattttg gatacgttaa aacgacataa tctagcccct aagcgcctgc agtttgttta
    11461 tccaaaaaga gaaaaggaag ccaatatgct tttgattgag gcgatcaagg atggctcaac
    11521 aagtggcttt aaggtcttac ctcctttgat tgtccacaat gatgatggct cttatacgcc
    11581 cgaaatcgaa gagatttatt atggatcata aggcttatat gtacgttctg gagtgtcgtg
    11641 atggatccta ctatataggc tatacgactg atatgagaag acgcctcgct atccacaata
    11701 gtgggaaggg agccaaatat acacgagcac gcttgccagt caaacttatc tatgctcaag
    11761 gttttgccag taaggaagaa gccatgtcgg ctgaagctct tctcaagcgt aagaagaggc
    11821 cacagaagga agaattttta tctgaaaatc aagatagaaa tttactcagt tattttgaag
    11881 aatcgtgggg agtcctttga ctcctcttac ctttgtcaaa aagcgaaaaa aatgctacaa
    11941 taaagaaaat aaacaaaatg aggtattatc atgtccaaga ttctagtatt tggtcaccaa
    12001 aatccagact cagatgccat cggatcatct gtagcttttg cctaccttgc aaaagaagct
    12061 tacggtttgg atacggaagc tgttgccctt ggaactccaa atgaagaaac agcctttgtc
    12121 ttgaactatt ttggtgtgga agcaccacgt gttatcactt ctgccaaagc agagggggca
    12181 gagcaagtta tcttgactga ccacaatgaa ttccaacaat ctgtatcaga tatcgctgaa
    12241 gtagaagttt acggtgttgt agaccaccac cgtgtggcta actttgaaac tgcaagccca
    12301 ctttacatgc gtttggagcc agttggatca gcgtcttcaa tcgtttaccg tatgttcaaa
    12361 gaacatggtg tagctgtgcc taaagagatt gcaggtttga tgctttcagg tttgatttca
    12421 gatacccttc ttttgaaatc accaacaaca cacccaacag ataaaatcat tgctcctgaa
    12481 ttggctgaat tggctggtgt gaacttggaa gaatatggtt tggcaatgtt gaaagctggt
    12541 accaacttgg ctagcaaatc tgctgaagaa ttgattgata tcgatgctaa gacttttgaa
    12601 ctcaacggaa ataatgtccg tgttgcccaa gtgaacacag ttgacatcgc tgaagttttg
    12661 gaacgccaag cagaaattga agctgcaatg caagctgcca acgaatcaaa cggctactct
    12721 gactttgtct tgatgattac agatatcgtc aactcaaact cagaaatctt ggctcttggt
    12781 gccaatatgg acaaggtcga agcggctttc aacttcaaac ttgaaaacaa tcatgccttc
    12841 cttgctggtg ccgtttcacg taagaaacaa gtggtacctc aattgactga aagctttaat
    12901 gcgtaagatt ttgggtgtca gctcaaaatc ggaaagtcta gtttgcctta tatcgaaagg
    12961 agtttcggct ccttttttct aggagtgaag tatgttagaa aatggcgatt tgatttttgt
    13021 gagagatggg tcagacatgg gacaggccat ccagacttcc acaggtaact atagccatgt
    13081 tgccatttat ttggatggga tgatttatca tgctagtgga caggctggtg ttgtctgtca
    13141 agaaccggca gacttctttg agtccaatca tttatacgac ctctatgttt acccagaaat
    13201 ggatatccag tcggtgaagg aaagagcttg caaacatctt ggagcaccct acaatgcttc
    13261 tttctatcca gatgcacctg gtttctactg ctcccagtat atagcagaaa tcctacctat
    13321 ttttgaaact attcctatga aatttggaga tggggagcag gagattagtg atttttggag
    13381 ggagtattac atagaactag gtctgcctgt tcctctgaac caagctggta ccaatcctag
    13441 tcagttggca gcatcgcctc tgttacaatg taaagaaagg aatcttcatg attcagattt
    13501 ttaatccatc tcgtttgacg agacagccat ttttggagaa ttgatccgct atctggacca
    13561 gtatgaggat gtgattctac gggaaattaa ggctcaattt ccagatgttg cagttgataa
    13621 actcatggaa gagtatataa aggcaggctt gattctacgt gaaaataagc gctattacct
    13681 caattttcct acgcttgaat cacttgatag tcttgaactg gatcaagaga tttttgtcag
    13741 agaagctagt ccggtctatc aagccttgtt ggagcagagt tttgagacgg aattgcgcaa
    13801 tcaaatcaat gcagctattt tagttgaaaa gacggacttt gcgcgcatta aaatgactct
    13861 gtccaattat ttttacaagg tcaaacagca gtatcctttg acagaaaaac agcaggagct
    13921 ctatgacatt ttaggagatg ttaatcctga gtatgcactc aagtatatga cggctttttt
    13981 gttgaaattt ctcaaaaaag accagcttat gcagaaatgc cgtgatatct ttgtggacag
    14041 tttggttgtc ttaggctata ttgtgcaaaa tgaagatgga aagtatgagt tggctatcga
    14101 ttttgataag gagagattaa ctttctactt agcgtgattt cttgtttctg agtacattgt
    14161 ttgactttcc ttagtattcg gtataaacta tatgtaaccg gtaacacata tcggaataaa
    14221 ctaaaggaga caatcatatg tcacttgaaa acaaattgga acaagcaaca ggcgctgtca
    14281 aagaaggttt tggtaaagtt actggagaca gcaagacaga acttgaagga gctgttgaaa
    14341 aaacagttgc taaggcaaaa gacgttgtag aagacgcaaa aggtgctgta gaaggtgccg
    14401 ttgaaggttt gaaaaacgtt tttactaaag aataggaaaa aatcaagggt ttcattttcc
    14461 cttgattttt tctattctta taaataattt tctgcgacgg ctgtatctcc tgggtaggat
    14521 tctttcttgc cctggatgat ttggtaacaa tcggctccct tacccgcaat aataactgca
    14581 tctaattcgt gatttgtgat agccattgcc gccttgatgg cttcttggcg atccgcaatc
    14641 ttctcaacag gatgattgat gtagctacta atttcatctg caatggccat tgggtcttca
    14701 tagttagggt catcagcagt cagaaagact tgaatctcag ggtgttgatt gaggaggagg
    14761 ccaaagtcct tacgacgact ttctcccttg tttcctgttg atcccagaac cagagcaatc
    14821 tttccggttt gatgagtttc aaccacattg atgagttttt tcagactatc cccattgtgg
    14881 gcatagtcga tgaagacctt ggctccattt ttctgagtga ggacttccat acgaccagga
    14941 acgcgggttg cagcgatgcc ttttttgatg tcctcaagac ttgctccgag acggagacaa
    15001 gcaagtccag cagcaactgc attttcttgg ttgaagttgc caatgagttg gatatcataa
    15061 tctccagcga gtttacccgt agctgaaaag ctaaaggctt tggaattctc gatttggtta
    15121 tcaaattggc taccatagaa atcatggtct tgatctttaa cctgttcttt caagactgag
    15181 aagtggtcca tgtcactgtt aatgatgact gctcggctat tttccatcaa gagacgcttg
    15241 tggtagaaat agtcttcaaa gctagggtgt tcaatcgggc cgatatggtc tgggctgata
    15301 ttgaggaaaa ctcccacatc aaaggttaga ccatagacac gtctgaccag ataggattga
    15361 ctggagactt ccatgatgag gtgggtacgg tcattttgca cagcctgatt catcatgtca
    15421 aagaggtcaa tactctcagg ggttgtcaac gctgacttaa agaaagtctc gccatcaaga
    15481 gttgtgttca tggtcgacaa catagcaggt cgatgccctt gagataagat gttataggcg
    15541 aaataggctg ctgttgtctt acccttagta ccagtaaagg caaggagttt gagtttttcc
    15601 tgtggattac catagaactc catggcaatc aaactcatgg ctttctttat atcgttcaca
    15661 atgatgacag ggataccgac ttcgtagtcc ttttcagcta cataccaagc taagccttgt
    15721 gttatagcag aaagaaggta ttctttttta aaggcagcgc cttttgcaaa aaaaagagtg
    15781 tcttctgtta cttttcggct gtcgtagctg atgctatcaa aaacaacttt gctgtagttg
    15841 tagtggtaat gaccttggtc aataatttcg cgaaaaaggc catctttctt taaaatatct
    15901 aatacagttt caatttttat catactttct attgtaaacc gaaagtcgca aatttacaag
    15961 taacaaggaa aagtttataa tggaagataa ggagtttttc ctagttatca aaattgaatg
    16021 aggaatctat gtcgcacgaa aacaatcacc agcaggccca gatgttacgg gggactgctt
    16081 ggctaacggc tagtaacttt atcagtcgcc tactcggggc tgtttacatt atcccttggt
    16141 acatctggat gggggcttat gcagctaagg caaatggtct ctttaccatg ggttacaata
    16201 tctatgcttg gttcttgttg gtttcaacag cggggattcc agttgcggtg gccaagcaag
    16261 ttgccaagta taataccatg cgagaagaag agcatagctt tgccctgatt cggagcttct
    16321 taggctttat gacaggacta ggcctggttt ttgctttagt cttgtatgtc tttgctcctt
    16381 ggctagcaga cttgtctggc gtgggcaaag acttgatccc aatcatgcaa agcttggctt
    16441 ggggagtctt gattttcccg tctatgagtg ttatccgagg atttttccaa gggatgaata
    16501 acctcaaacc ctatgccatg agccaaattg ctgagcaggt cattcgtgtt atctggatgc
    16561 tcctagcaac ctttatcatt atgaagctcg gttcaggaga ttatctagca gccgttaccc
    16621 aatcaacctt tgctgccttt gtcggtatgg tagccagttt tgcagtcttg atttatttcc
    16681 ttgcccaaga aggttcactc aaaagagtct ttgaaacagg agataagatt aacagtaagc
    16741 gtctcttggt tgataccatt aaggaagcca ttccttttat cctgacaggg tctgccatcc
    16801 agctcttcca gattttggat cagctgacct ttatcaatag tatgagctgg tttaccaact
    16861 acagcaatga ggacttggtt gtcatgtttt cttatttctc agccaatcct aataaaatca
    16921 cgatgatttt gatttctgta ggggtttcga ttgggagtgt tggtttgcca cttttgacgg
    16981 aaaactatgt caagggggac ttgaaagcag cttctcgtct ggttcaggac agtctcaccc
    17041 tactctttat gttcttgcta ccagcaacgg ttggagtggt tatggtagga gaacctctat
    17101 atacagtctt ctatggtaag ccagatagtt tggctctggg cttatttgtc tttgcagttt
    17161 tgcagtctat tattttaggc ttgtacatgg tcttgtctcc aatgcttcag gccatgttcc
    17221 gcaaccgcaa ggccgttctc tattttatct atggttctat tgccaagcta gtcttgcaac
    17281 tacctaccat cgccctcttc cacagttatg gtcctttgat ttcaacaacc attgctctca
    17341 tcattcctaa cgtcttgatg tatcgggata tttgtaaagt aactggtgtc aagcgcaagg
    17401 tgattttgaa gcgaaccatt ttaatcagtt tgctgaccct agtcatgttt ctgttaatag
    17461 gaaccatcca gtggctgtta ggatttttct tccaaccaag tggacgtttg tgtagcttct
    17521 tttatgtagc tcttgtcggt gccatggggg gtggacttta tatggttatg agtctgcgta
    17581 cctatttatt agataaggta ataggaaaag cccaagcaga tcgcctgcga gcaaaattta
    17641 agctttcgta aggtagcatt tataaataaa aggaataagt tgaacaatct tttaggagaa
    17701 cttgaagctt attccttttt tagcgtaaaa atagctaaaa ttatatttca aaaatagaaa
    17761 atgaggcttt tttcgatttt ttggaaaaaa tcattgacta aacaaactaa acgttgtata
    17821 ataaaacaaa tatttaaagc aggaggttcc ggaaatgaaa aagtctaaga gcaaatatct
    17881 aaccttggca ggtcttgtcc tgggtacagg agttttattg agcgcgtgtg gaaattctag
    17941 cacggcgtca aaaacataca actatgttta ttcaagtgat ccatctagct tgaactatct
    18001 agcagaaaac cgcgcagcaa catccgatat tgttgcaaat ttggtagacg ggttattaga
    18061 aaatgaccaa tatgggaata ttattccatc attagcagag gattggactg tttctcagga
    18121 cggtttgacc tatacctaca aacttcgtaa ggatgccaag tggtttactt ctgagggaga
    18181 agaatatgcg cctgtaactg cccaggattt tgtgacaggt ttgcaatatg cagctgataa
    18241 aaaatcagaa gccttgtatc tagtgcagga ctctgttgct ggtttggatg actatatcac
    18301 tggtaaaaca agcgactttt caactgtcgg tgtcaaggca cttgatgacc aaacggttca
    18361 atatactttg gttaaaccag aactttactg gaattcaaaa acacttgcaa cgatactttt
    18421 tcctgttaat gcagatttcc tgaaatcaaa aggggatgat tttgggaagg cggatccatc
    18481 tagtattttg tacaatggac ctttcttgat gaaagcactt gtctcaaaat ctgctattga
    18541 atataagaaa aaccctaatt actgggatgc taagaatgtc tttgtagacg atgtgaaatt
    18601 gacctactat gatggtagcg accaagaatc actggaacgt aattttacag ctggtgctta
    18661 tactacggct cgtctttttc ctaacagctc cagctatgaa gggattaaag aaaaatacaa
    18721 aaacaatatc atctatagtg tgcaaaattc aacttcatat ttctttaatt ttaacctaga
    18781 taggaagtct tacaattata cttctaaaac aagtgacatt gaaaagaaat cgacccagga
    18841 agcagttctc aataaaaact tccgtcaggc tatcaatttt gcttttgaca gaacatctta
    18901 tggggctcag tctgaaggga aagaaggtgc aacaaagatt ttgcgtaacc tagtggttcc
    18961 tccaaacttt gtcagtatca agggaaaaga ctttggtgaa gttgtagcct ctaagatggt
    19021 caactatggt aaggaatggc aaggtatcaa ctttgcggat ggtcaagacc cttactacaa
    19081 tcctgagaaa gccaaggcta agtttgcgga agctaagaaa gaactcgaag caaagggtgt
    19141 tcaattccca atccacttgg ataagactgt ggaagtaaca gataaagtag gcatacaagg
    19201 agttagttct atcaaacaat caattgaatc tgttttaggt tctgataatg tagtgattga
    19261 cattcagcaa ttaacatcag atgagtttga cagttcaggc tactttgctc aaacagctgc
    19321 tcagaaagac tatgatttat atcatggcgg ttggggacct gattatcaag acccgtcaac
    19381 ctatctcgat atttttaata ctaatagtgg aggagttcta caaaatcttg gactagagcc
    19441 tggagaagcc aatgacaagg ctaaggcagt tggactggat gtctatactc aaatgttgga
    19501 agaagctaat aaagagcaag atccagccaa acgttatgag aaatatgctg atattcaagc
    19561 ttggttgatt gatagttctt tagttcttcc aagtgtttcg cgtgggggaa caccatcatt
    19621 gagaagaacc gtaccatttg ctgctgccta tggtttaacc ggtacaaaag gggttgaatc
    19681 atataaatac ctcaaagtac aagataagat tgtcacaaca gacgaatatg caaaagccag
    19741 agaaaaatgg ttgaaagaaa aagaagaatc caataaaaaa gcccaagaag aattggcaaa
    19801 acatgtcaaa taaaatctaa ttgtagataa gtttgtgtaa gaagtctttg tgcttaaaaa
    19861 cgcataatat caggtatata aaatcctaga tgttatgcgt tttgttatag gaagatttat
    19921 tagattttat cctcaaattg agttattccc gactttatcc gttgaaatat tataaggagt
    19981 atttatgaaa ttaaaattat taagagtaga tactaaggtg attatgggga gtttcttact
    20041 tgttctgtct agtctacttg ctttgttgct tccccttatc ttaaagggtt taatagatgg
    20101 gagttctatt gaaaatatag gttccaaagt atttcaatcg tttttgattt ttattggtca
    20161 agccttgttt tcttctattg gttactatct gtttagtcaa tcgggtgaaa aaagatagca
    20221 aaaatcagga aaaaagtgat agaggggttg atttatgcag agaaatcctt ctttgataag
    20281 agccaaagtg gggagttgac ttctgccatt gtcaatgaca tgagtgtcat tcgtgagttt
    20341 ttaattacga ctttcccaaa tattattctg agtttagtta tggtacttgg ttccattgta
    20401 gtcttattta gtcttgattg gaatctttct ctacttttat tcatcactct tccttgtatg
    20461 atgtttatta tcttgcccct ttccaatatc agtgaaaagt atagtcgtcg tttacaggag
    20521 gaaatcggat ttttaacagg gcaattgact gaaaagattc aagaacatga attaattaag
    20581 actaaccaag cagagaaaag tgtacaggat gttttggata attgtattga aagggtacaa
    20641 aacaattcac tgaaatcaga tagggttact tcttttgaga ccccgtttgc tctcttattt
    20701 atctttgcga ctatagttgt gatgctaacc tatgggggtt atcgggtcag cgcaggatat
    20761 atatctgtgg gaaccttggt ttcgtttttg atttacctct ttcaattact taatcctatt
    20821 agtaatatag ctaattttgt aactatttat tctagtagca agggatcttc agttgcactg
    20881 gagaacttgc ttgcagttcc taaagaaaaa tttgagggag gaaaatcggt atcaggacaa
    20941 gggttgaatt ttaaccatgt ctattttggt tatgatgaaa atcgacctgt cttaaaggat
    21001 attacttgtt caattttcaa ggggcaaaaa attgcttttg ttgggccatc tggatcagga
    21061 aaatcaacga ttgtgcgttt gttagagcgg ttttataaac cgctttcagg agatattcta
    21121 atggagcaat caagtatata tgattttaac ttaaaagaat ggagaagtaa aatcgcttgg
    21181 gtttcacaaa ataatgcagt cttatctggc agtattcgtg acaatctttg tctcggtttg
    21241 aatcgcttag taactgatga tgaattgatg aaagtgctag acttagtatc actaggtgat
    21301 gagattcgct ccatgaaaga gggactagat actgaagttg gtgaacgcgg acgactcttg
    21361 tcaggggggc gaagccaaag acttcaaata gctagagcct acttaaaaga tgctgaaatt
    21421 cttatatttg atgaagccac tgctaatctt gatgcggatt ctgagtatgc gattatcagt
    21481 agcctctatt ctgtactaaa ggagaagacg gttgtgatta tagcgcatcg cttgtcaacg
    21541 gtaaaagatg tggattgtat tttcttctta gaggagggga aaatcactgg ctcaggaact
    21601 cataaggaac tactggaaaa tcatgagcgt tatgctcgtt ttgtgcagga gcaaatgata
    21661 gagtgaaggt gtcttttgag attcaccatt ttatagtcta ttaaagggag caggaaaaac
    21721 tcccttttta tatagtttga aactataact agctcttgaa aagaagaaaa tgagttgatg
    21781 aaaataagtg gtacaatagt tactatagat ttggaggaat tgtatgagca aggaattaca
    21841 cattaacaca attttagcac aagcagggat caagtctgat gaggcaacag gtgctttggt
    21901 gacaccactt catttttcaa cgacctatca gcatccagag tttggtcgat ctactgggtt
    21961 tgactatacg cgcactaaaa atccaactcg tagtaaggct gaggaagtct tggcggctat
    22021 tgagtcagca gactatgccc tagcgactag ctcagggatg tcagctattg tactggcctt
    22081 tagcgtcttt ccagtaggaa gtaaggtctt ggcagtgcgt gatctttacg gtggttcttt
    22141 tcgctggttt aaccaagtgg agcaggaagg tcatttccat tttacctatg ccaatacaga
    22201 agaagagttg attgccgagt tagaaaagga tgtggatgtt ctctatatcg aaaccccaac
    22261 caatcccttg atgttggaat ttgatatcga aaaactagca aaattggctc atgctaaggg
    22321 tgccaaagtg gtggtggaca ataccttcta tagccctatc taccaacgtc cgattgaaga
    22381 tggagcagat atcgttctcc attcagcaac caagtatcta gcaggccaca atgatgtctt
    22441 ggctggagtg gttgtgacca atagtttaga actatacgag aagctttttt acaatcttaa
    22501 tacaacaggg gcagtcttgt ctccatttga cagctaccag ttgcttcgtg gtctcaagac
    22561 cttgtctctt cgtatggagc gctcaacagc taacgcccaa gaagtggttg cctttttgaa
    22621 ggattctcca gcagttaagg aagttctcta cactggtcgt ggaggcatga tttcctttaa
    22681 agtagccgat gaaacacgca ttcctcatat tttgaacagt ctcaaggtct tctcttttgc
    22741 ggaaagtttg ggtggagtgg aaagtcttat tacttatcca acgactcaaa ctcatgctga
    22801 tattccagca gaagtacgcc attcttatgg tttgacagat gacctcttgc gtttgtctat
    22861 tgggattgag gatgctagag atttgattgc agatttgcgc caagccttag aaggataaga
    22921 caaagatggg aaaatatgat tttacaagcc tgcccaaccg tttagggcac catacctata
    22981 aatggaaaga aacagaaacg gatagtgaag ttctaccagc ttggatagcg gatatggact
    23041 ttgtagtctt gcctgaaatc caccaagccg tgcaaactta cgcagaccaa ctggtttatg
    23101 gttataccta tgccagtgaa gacttaatta aggaagttca aaagtgggaa gctacacaat
    23161 acggttacaa ctttgacaaa gaggctcttg tctttatcga gggtgtggta ccagccatct
    23221 caacagctat tcaaaccttt acaaaagaag gcgaggcggt tttaattaac acgcctgtct
    23281 acccaccctt tgctcgcagt gtcaagttga ataatcgtag attgattact aattccttag
    23341 tggaaaagga tagtctgttt gagattgact ttgaccaact tgaaaaggat ttggtggaag
    23401 aggaggttaa actctatgtt ctttgcaacc ctcacaatcc tggtggacgt gtttgggaaa
    23461 aagaagtgtt ggagaagatt ggccaactct gccaaaaaca cggtgttttg ttagtttcgg
    23521 atgagattca ccaagatttg accctctttg gtcacaaaca ccagtctttc aataccatca
    23581 atcctgcctt caaaaatttt gctatcgtct tgagcagtgc cactaaaaca tttaatattg
    23641 ctggaacaaa aaattcctat gcagtcattg aaaatcctaa gttgagactg gctttccaga
    23701 aacgcctgtt ggccaataat cagcatgaaa tttcaggctt gggttatttg gcgacagaag
    23761 ctgcctatcg atacggtaaa gattggctag aggaactcaa gcaagtcttt gaagaccaca
    23821 tcaattatgt ggtggatcta tttggaaaag agactaaaat caaggtcatg aaaccgcaag
    23881 gtacctactt gatttggctt gacttttcag cttatgacct gactgatgaa acattgcaag
    23941 agttgttgag aaatgaagcc aaggttatcc tcaaccgtgg tttggatttt ggagaggaag
    24001 gaagtctcca tgcccgcatc aatatagcta tgcccaaatc tctgttgcaa gaagtctgtc
    24061 agcggattgt ggctactttt gccaaatgtt aaaaatccag ccttctagga gaaaagtctt
    24121 cctagaaggc tattttcata ggcgaaaata tggtataata aaaagataag gtaaaggtga
    24181 aaatatggct aaattgattc cggggaaaat tcgtatcgaa ggtgttgccc tttatgaaac
    24241 tggtaaggtt gatatcatca aggaaaagaa caatcggctc tacgctcgcg ttgcagaaga
    24301 agaactgcgc tatagtttag aggatgattt gattttttgt gcctgtgatt tttttcaaaa
    24361 gaggggctac tgtgtgcatt tggcagcgct agagcatttt ctgaaaaatg atgagcgtgg
    24421 tcaggaaatc ttgtggagtc tggaagaagg tcatgaagaa aaagaggccg ttgaaaccaa
    24481 ggtgaccttg ggtggcaagt ttttggatcg aattttatct ccaaaatcag aatgcgccta
    24541 tgagttatca gctgtgggtc aggtggaagc aggaaccaat catatcttgt ggactctgag
    24601 aatcggccaa atcaatagcc aaaaatacta tgtcattcgg gatattccac tttttttaag
    24661 gattgtcgag cagagaaagt cgtatatgat tggcaagatt tatgaggagt ctctttcttg
    24721 ggaagccttt gatgatgcca gccaagaact tttgactttc ttgcacggac taacggagga
    24781 agggctggtt ccagacctct ttttccaaaa ccaaggtcgg cacctctttt tccctctgac
    24841 cttttttgag cagggtgtga atttactgat ggccttgccc cattttcaat ttgaccatca
    24901 agtggatagc taccaaaccc tgctttttca ggatatgcat gctgatgcca atctatttgc
    24961 ctttacagta acagaatatt cggactattt tgaaatggaa atcagtgaga gtcctagggt
    25021 caatgtcttt tatcaaggag cagtactttt ccataaaggt caggtttatt ttttaacaga
    25081 ccagcagatg cgtcttctca aggaaattaa agcgttacct gtggatcgac aaggaaagaa
    25141 atacctgcaa tttgatagca gtgatcgaga caaattggcc tcctgtctga ctctttttat
    25201 ccagatgggc accgtttcag ctccagaacg tctacaaatc aaaacttttg cgccctcttt
    25261 ttactttgac agggaagaag ataatcggat tcgtttagaa attcagtttg attatggaaa
    25321 tagacaggta tctagccgac aagagctaga agaattacca ttttcaagtg acgcggactt
    25381 agaagaaaga attttccaag tctgtttggc tgcgggcttt gaagccgatt ttcaatcttg
    25441 gcgtcaggcc ttaaaagcgg agtctgtcta tcattttttt catgatatca ttccagtctt
    25501 tgaaaaactc gggcatgttg acctatcaga taaactagaa gagctttata gcctagcgag
    25561 tcctcaggtg cagattgcct ccaagggagg tctcttggaa atccagtttg attttcaaga
    25621 tattgcccag gaggaaatcg accaagccat acaggccttg gttgccaatc aggattttta
    25681 tattgattcg tctaatcaag tttacttttt cgatgaagaa accaagaaaa ttcgccaaaa
    25741 tctacaggaa ctggggcaat ttgaattaaa agatgggacc ttgcaggctc ggaaatcctt
    25801 ggcctacagt ttagctcatc tctttgaagg gcgagaccgt gtttcttttt cacaagaatt
    25861 ccagaatctg gcccaggatt tgacgcatcc agaggacttt cctttgcaag caactcaggt
    25921 caaggctgac ttgcgagatt atcaggaaaa gggaattggc tggttgcaga tgctccatca
    25981 ttatggtttt ggtgggattt tggctgatga tatgggactt gggaaaaccc ttcagaccat
    26041 tgcttttttg actagtcaag tgacaaaaga aagtcgggtt ttgattctcg ctccgtcggg
    26101 tttgatttac aactgggcag atgagtttca gaaatttgct ccacagttgg atgtggctgt
    26161 tgttcatggt ttgaaagcaa gtcgtgagga gattcttgcc gagagccatc aaatctatgt
    26221 gactagctat gccaccttcc gtcaggacag tgagctttat caggggatgg cctttgactt
    26281 ccttttctta gatgaagctc aggtcatgaa aaatgcccag accaagattg cccagacctt
    26341 gagacaattt gtggtgccgt cggtctttgc cttgtcagga actccgattg aaaaccatct
    26401 gggtgagttg tggtctattt ttcaaatcgt catgcccgga cttttgccaa gcaagaaaga
    26461 atttatgaaa ttgccagcag agcgagtggc tcagtttatc aagcctttcg tgatgcgacg
    26521 caagaaagaa gaagttctga ctgaattgcc agacttgatt gaggtggttt ataaaaatga
    26581 actggaagac cagcaaaagg ctatttacct tgcccagtta caacagatgc gagaccatct
    26641 ggctcaagtg tcagaacagg aatttcagcg aagtcgtgtg gaaattttat ctggtttgat
    26701 gcgcttgcgt caaatatgtg acactcctgc cctgtttatg gaagattatc agggagccag
    26761 cggcaaacta gatagtctcc gagacctact ggtacaggtg gcagacggcg gacaccgtgt
    26821 cttgattttc tctcagttca agggaatgtt ggaaaaaatt gaacaagaac tgccagactt
    26881 gggcctgaca tcctttaaaa ttacgggttc aaccccagcc aaggaaagac aagacatgac
    26941 caaggccttt aaccaaggag aaagagatgc ctttctgatt tccctcaagg ctggtggggt
    27001 cggtctgaac ctgacaggtg cagatacagt gatcttggtt gacctttggt ggaatcctgc
    27061 ggtggaagcg caagccattg gccgtgccca tcggatgggt caggaagaaa cggttgaggt
    27121 ctatcgcttg gtgaccaagg gaaccattga agaaaaaatt caggaactcc aagaacaaaa
    27181 gaaacatctg gtgtcacaag tattggacgg cacagagtca cgtggtagtc tgaccctagc
    27241 agaaattaga gaaattttgg gaatttctga agccagcact tgaaaaatca agacaatacg
    27301 ctataatgaa gtgttgaaag gaaatagaaa atgaaacaag aacgatttcc attggtgtca
    27361 gatgacgagg tcatgttgac tgaaatgcca gtcatgaatc tctatgatga gtctgatctg
    27421 atcagtaata tcaagggtga gtatcgagat aaaaattatt tagaatgggc tcctattgct
    27481 gaagaaaaac cagtaaaacc gattgaaaag caagtaggga aacctaaaaa agctccttta
    27541 ggggttaaaa aagaaggaaa gagctatgcg gaggtggcgc gtgaagaagc gcgtgcagac
    27601 ttgaaaaaga aacgctctgc taactatcta actcaggatt tcagccttgc gagacgtcat
    27661 tctcagccca gtctagttag acagggcaat caaccgacaa ctcctttcca aaaggaaaat
    27721 cctggtgaat ttgtcaaata tagccaaaaa ttgacccagt ctcattatat cttggcggaa
    27781 gaagttcatt ctatccctac caagaatgaa gaagtgtcag cacctgctcc aaagaaaaac
    27841 aattatgatt ttctaaagaa gagccaaatc tacaataaaa aaagtaaaca aacagaacaa
    27901 gaacgtcggg ttgcccaaga gttgaatctg accagaatga cagaataggg gagaaaacat
    27961 gtcaaagaca tatcatttta tcggaattaa gggatcaggg atgagtgcct tggccttgat
    28021 gttgtaccag atggggcaca aggttcaggg atcagatgtt gaaaagtact actttaccca
    28081 acgcggtctt gagcaggcag gaattaccat tcttcctttt gatgaaaaga atctagacgg
    28141 tgatatggaa attatcgctg gaaatgcctt tcgtccagat aacaacgtcg aaattgccta
    28201 tgcggaccaa aatggtatca gctacaaacg ttaccatgag tttctaggta gctttatgcg
    28261 tgactttgtt agcatgggag tagcaggagc acatggaaaa acttcaacga caggtatgtt
    28321 gtctcatgtc ttgtctcaca ttacagatac cagcttcttg attggagatg ggacaggtcg
    28381 tggttcggcc aatgccaaat attttgtctt tgaatctgac gaatatgagc gtcacttcat
    28441 gccttaccac ccagaatact ctattatcac caacattgac tttgaccatc cagattattt
    28501 cacaagtctc gaggatgttt tcaatgcctt taacgactat gccaaacaaa tcaccaaggg
    28561 tctttttgtc tatggtgaag atgctgaatt gcgtaagatt acgtctgatg caccaattta
    28621 ttattatggt tttgaagctg aaggcaatga ctttgtagct agtgatcttc ttcgttcaac
    28681 aactggttca accttcaccg ttcatttccg tggacaaaac ttggggcaat tccacattcc
    28741 aacctttggt cgtcacaata tcatgaatgc gacagccgtt attggtcttc tttacacagc
    28801 aggatttgat ttgaacttgg tgcgtgagca cttgaaaaca ttttccggtg ttaaacgtcg
    28861 tttcactgag aaaattgtca atgatacagt gattatcgat gactttgccc atcatccaac
    28921 agaaattatt gcgaccttgg atgcggctcg tcagaaatac ccaagcaagg aaattgtagc
    28981 agtctttcaa ccgcatacct ttacaagaac cattgccttg ttggacgact ttgcccatgc
    29041 tttaaaccaa gcagatgctg tttatctagc gcaaatttat ggctcggctc gtgaagtaga
    29101 tcatggtgac gttaaggtag aagacctagc caacaaaatc aacaaaaaac accaagtgat
    29161 tactgttgaa aatgtttctc cactcctaga ccatgacaat gctgtttacg tctttatggg
    29221 agcaggagac atccaaacct atgaatactc atttgagcgt ctcttgtcta acttgacaag
    29281 caatgttcaa taggatgttc ccatggaaat tccaattaag atcattcagg caagcaagtc
    29341 tgatttgcct gagatagggg cacttcagac ctcgtctttt ccagctgaaa agcagcaact
    29401 ttcccatatt ttagaagaaa gtatccgtaa gtgtgcggat acctttcttc tagctaggga
    29461 tgaaaatcaa cttttaggct atattttatc aagtccccag tcagacaatc cgcaatatct
    29521 aaaagtacat tctttagtca tcgagtctga ccatcagaga cagggcttgg gaacacttct
    29581 tcttgcagcc ttgaaagagg tggcagttga gctggattac aaagggattc gtttggagag
    29641 tcctgatgag ctgctttcct attttgaaat gaacggtttt gttgatgaag aagcaacttt
    29701 gctctatgca actagccagg gctatagtat gatttggttt aatccctttt atctggagga
    29761 acaatgaaaa tcagacaagc aagattagaa gatttggatc ggattgttga acttgaattt
    29821 gaaaattttt cggtcgaaga agccattcct ccttctgtct ttgaagcaca tttgagagaa
    29881 attcagacct cttttctggt tgctgaaaaa gaaggaagaa tcatgggtta tatcgaagga
    29941 ccagttggcc tgcaccgcca tctgcaagac cagtctttta cagaagaaat aaaagactat
    30001 agtcatgagc ctggtggtta tatctctgtg acctgtctgt ctattgccaa ggaggcacag
    30061 ggactcggac tgggtcagaa attgctgaca gccttgaaag aagttgctct tgaagatgag
    30121 agagatggca ttaatctaac ctgtcatgac tatctcatcg cctactatga aaaacatgga
    30181 tttgtcaacg aaggccagtc ccagtcaacc tttgcagggg aaacatggta tgatatggtc
    30241 tgggaaatga aaaaataagt taggaaaagt atcatagatt gctttttttg gacttttaag
    30301 atataatatt atggattatc aacaaggagg aaaaactttt gagtgaaaag tcaagagaag
    30361 aagagaaatt aagctttaaa gagcagattc tgagagattt agaaaaagta aaaggctatg
    30421 atgaagttct gaaagaagat gaggcagtag ttcgcactcc tgcaaatgaa ccttcaactg
    30481 aagaactcat ggctgattcc ttgtcaacgg tagaggagat tatgagaaaa gctcctaccg
    30541 tgcctactca cccaagtcaa ggtgtaccag cttctccagc agatgagatt caaagagaaa
    30601 ctcctggtgt tccaagtcat ccaagtcaag atgtaccttc ttctccagcg gaagaaagtg
    30661 gatcaagacc aggtccaggt cctgttagac ctaagaaact tgaaagagaa tacaatgaaa
    30721 ccccaacaag ggtagctgtt tcctatacga cggcagagaa aaaagcagaa caagcaggtc
    30781 cagaaacacc tacgcctgct acagaaacag tggatatcat cagagataca tcacgtcgta
    30841 gccgtagaga aggagcaaaa cccgttaagc ctaagaaaga gaagaagtca catgtgaaag
    30901 cttttgtgat ttcattcctt gtattccttg ccttgctctc agcaggtggt tactttggtt
    30961 accagtacgt gctagattcc ttattaccta tcgatgctaa ttctaagaaa tatgtgacgg
    31021 ttggaattcc agaaggttca aacgttcaag aaatcggtac gacgcttgaa aaagctggtt
    31081 tggtaaagca tggtctgatt tttagttttt atgccaagta taaaaattat accgacttga
    31141 aagcaggtta ctacaatttg caaaagagta tgagtacaga agacttactc aaagagttgc
    31201 aaaaaggtgg aacagatgaa ccgcaagaac ctgtacttgc gactttgaca attccagaag
    31261 gttatacctt ggatcagatt gctcaagctg tgggtcaatt gcaaggtgac ttcaaagagt
    31321 ctttgacagc ggagactttc ttggctaaag ttcaagatga gacgtttatc agtcaagcag
    31381 tagcgaaata tcctacttta ctggaaagtt tgcctgtaaa agacagcggt gcgcgttatc
    31441 gtttggaagg ataccttttc ccagctacat actctatcaa ggaaagcaca actattgaga
    31501 gcttgattga tgagatgtta gctgctatgg ataagaacct atctccttac tatagtacta
    31561 tcaaatctaa aaacttgact gtcaatgagt tgttgaccat tgcttccttg gtcgaaaaag
    31621 aaggtgccaa gacagaagat cgtaagctca ttgcaggtgt attctacaat cgtttgaatc
    31681 gtgatatgcc acttcaaagt aatattgcaa tcttgtatgc ccaaggaaaa ctggggcaaa
    31741 atatcagtct agctgaggat gttgcgattg ataccaacat tgattcacct tataatgttt
    31801 ataaaaatgt aggtctcatg cctggtccag tcgatagtcc aagtctggat gcgattgagt
    31861 caagcatcaa tcaaactaag agcgataacc tctactttgt agcagatgtc acagaaggca
    31921 aggtctacta tgctaacaat caagaagacc acgaccgcaa tgtcgctgaa catgtcaaca
    31981 gcaaattaaa ctaaacaaac taaaattatg ttatacttca cataattttc tttagaaaat
    32041 attatcagaa gaaagttgag aaaaatggca gaaaaaacat atcctatgac ccttgaggaa
    32101 aaggaaaaac ttgaaaaaga attagaagaa ttgaaattgg ttcgtcgacc agaagtggta
    32161 gaacgcatta agattgcccg ttcatacggt gacctttcag aaaacagtga gtacgaagca
    32221 gctaaggatg aacaagcctt tgtcgaagga caaatctcta gcttagaaac aaaaatccgc
    32281 tatgctgaaa tcgtcaatag cgacgcagtt gcccaggacg aagtagcgat tggtaaaaca
    32341 gtcaccatcc aagaaattgg tgaggacgaa gaagaagttt atattatcgt aggttcagct
    32401 ggtgcggatg cctttgcagg taaggtttca aatgaaagcc caattgggca ggccttgatt
    32461 ggcaagaaaa caggtgatac agcaaccatt gaaacgcctg ttggtagcta tgatgtaaaa
    32521 atcttgaagg ttgaaaaaac agcctaaaaa cagaaaaagg agtggggagg cgatgtgctt
    32581 cactcactcc tttttccatt ttgctattct tcgaaaatct cttcaaacca cgtcagcgtc
    32641 gccttgccgt atgtatggtt actgacttcg tcagtttcat ctacaacctc aaaaccatgt
    32701 tttgagccga cttcgtcagt ttcatctaca acctcaaaac catgctttga gctgacttcg
    32761 tcagtttcat ctacaacctc aaaaccatgc tttgagctga cttcgtcagt ttcatctaca
    32821 acctcaaaac catgctttga gctgacttcg tcagttctat ctacaacctc aaaacagtgt
    32881 tttgagcaac ctgcggctag tttcctagtt tgctctttga tttttattga gtattagatg
    32941 tatagtgcat tgaagttaaa atagtacact ttgatttcta agacattgtt agaaattaga
    33001 ttaaattcct taatcgattt gcgcatgttt tatttcattt cactatactt tagattggaa
    33061 aataaggaat cacataaatc gcaagaaata gggaatctga ttcgtgttta taaccgttca
    33121 aaaagagaag aggctgaaag tgagccactt aatctttatg tcgaagatga aaagggcaat
    33181 ctcctggcag gtttgatagc agagactttt ggaaattggc tagaaatcga gtatttgttt
    33241 gtaaaagagg aactgcgagg gcaaggaatc ggttcaaaac tattgcaaca ggcagaaagt
    33301 gaagctaaga atcgaaattg ttgttttgcc tttgtcaata cttaccagtt ccaggcaccg
    33361 gacttttatc agaaacatgg ctacaaggaa gttttttctt tgcaagacta tctctacatt
    33421 aggcaaagat attattacca aaagaatctg taaggtgagt atggaggtat aatacaaaga
    33481 gaggctcgca cataagtatg gaggtggact gatgtatatg agtaactatc gataaatacc
    33541 agttataacc tagaaattgt gtctttctag acgatattga ggacaatata atcgtagccc
    33601 caaaattagg aatcaagact tatcaggtta agaaaagaag tgatgttgtt gatattttaa
    33661 acaatttatt taaactaaaa actctctatc tattaatccg agattcccct ctcggatttt
    33721 gtgttgcttt cattaaattt acaggtaaga cttgctagct tcagtaaata tacacaagtt
    33781 tttcagaata gagtgaaatc caaaagaaaa tggaaataat gaaagctctt gtaggcataa
    33841 gaaaacacct ctgtgttata cttgttgttc aaccacaaac acaagaaagg cacagagatg
    33901 caagacaatt atactacaaa agccaaacat ttgacaatcg atagccgtcg cttaatcgaa
    33961 agatggaaaa aagaagggaa atcaaataga gaaattgcct ctctgcttgg aaaagttcct
    34021 caaactatcc acactgaaat caagcgtggg acagtccgac aatgtcttgg aaaagggcgc
    34081 ttcaaagagg tttattctgc cgactatgct caacagtctt atgaaaataa tcgcaagcgc
    34141 tcggtcaaga aatcaagctt gaccaaggaa ctaaaggaaa agattctcca ctatcataac
    34201 caaaaatttt cgcctgaaat gatggtgatg gctaaagggg ttaacgtggg aatttcaacc
    34261 atttactatt ggattcatca tggaaaattg gggttaagca aacaggatct gctttaccct
    34321 agaaaaggaa aagcgcttaa gaaacaggct agcaccaact ttaaacctgc tggtcaatcc
    34381 atcgaacagc ggtctgaagc tatcaatctt cgcttggaga atgggcatta tgagattgat
    34441 acggttctac ttacgagagc gaaaaactac tgcttgcttg tcttgacgga tcgaaagagt
    34501 agacatcaga tcatccgatt gattccaaat aaaagtgctg aggtggtcaa tcaggctcta
    34561 aaactcatct taaaacaaca caagattctt tccatcacgg cagataatgg aacggaattc
    34621 aatcgcttgt ttgatgtatt ttctgaggag cacatctatt atgcgcaccc ctatgcctct
    34681 tgggaaaggg gaactaatga gaatcacaac aggctcattc gtagatggtt acctaaggga
    34741 accaagaaaa tgactcccaa agaagtcgca ttcatcgaaa agtggattaa caactatcct
    34801 aaaaaatgct tggactacaa gtcacccaga gaagacttct ggatggctaa cttgaacttg
    34861 aaatttagca aaatggaaat aatttttatt aaacgcttcc aatagcggtt aaaagttgac
    34921 aaatttaaat tttaggacta cactaagtaa gtaaatttta ttttaaagga gaatttgtta
    34981 tgaatttaac atttttaggc ttatgtattg cctgtatggg cgtatctgtc ggtgaaggtt
    35041 tattgatgaa tggactgttt aaatcagtag cacgccaacc agatatgctt tctgagtttc
    35101 gtagtttgat gtttttaggt gttgccttta ttgaaggaac tttctttgta actcttgtct
    35161 tctcatttat tatcaaataa atacatggaa cgagaagaaa agggaggatt ttagatggaa
    35221 gaaagtatta atccaatcat ctctattggt cctgttatct tcaatctgac tatgttagcc
    35281 atgactttgt tgattgtggg agttattttt gtctttattt attgggcaag ccgcaatatg
    35341 accttgaaac ccaaaggaaa gcaaaatgta cttgagtatg tctatgactt tgttattgga
    35401 tttacagaac ctaacattgg ttcgcgctac atgaaagatt actcactctt tttcctttgt
    35461 ttattccttt tcatggtgat tgccaataac cttggcttaa tgacaaagct tcaaacgatc
    35521 gatgggacta actggtggag ttcgccaacc gctaatttac agtatgactt aaccttatct
    35581 tttcttgtca ttttgttgac acatatagaa agcgttcgtc gtcgtggatt taaaaaaagt
    35641 ataaaatctt ttatgagtcc tgtttttgtc ataccgatga atatcttgga agaatttaca
    35701 aacttcttat ctttggcttt gcggattttt gggaatatct ttgcaggaga ggtcatgacg
    35761 agtttgttac ttcttctttc ccaccaagct atttattggt atccagtagc ctttggagct
    35821 aatttggctt ggactgcatt ttctgtcttt atttcctgca tccaagctta tgtttttact
    35881 cttttgacat ctgtgtattt agggaataag attaatattg aagaggaata gaaaggagta
    35941 actgatgcac gtaacagtag gtgaattaat tggtaatttt attttaatca ctggctcttt
    36001 tattcttttg ctagtcttga ttaaaaaatt tgcatggtct aatattacag gcattttcga
    36061 agaaagagct gaaaaaattg cttcagatat tgacagagct gaagaagccc gtcaaaaagc
    36121 agaagtattg gctcaaaaac gcgaagatga attggctggt agccgtaaag aagctaagac
    36181 aatcattgaa aatgcaaagg aaacagctga gcaaagtaag gctaatatct tagcagatgc
    36241 taaactagaa gcaggacact taaaagaaaa agccaatcaa gaaattgctc aaaataaagt
    36301 agaagcttta cagagtgtta agggtgaggt cgcagatttg accatcagct tagctggtaa
    36361 aatcatctca caaaaccttg acagtcatgc ccataaagca ctcattgatc agtatatcga
    36421 tcagctagga gaagcttaat ggacaagaaa acagtaaagg taattgaaaa atacagcatg
    36481 ccttttgtcc aattggtact tgaaaaagga gaagaagacc gtatcttttc agacttgact
    36541 caaatcaagc aagttgttga aaaaacaggt ctgccttctt ttttaaaaca agtggcagta
    36601 gacgagtcgg ataaggaaaa aacaattgct tttttccaag attctgtgtc gcctttatta
    36661 caaaacttta tccaggttct ggcctacaat cacagagcaa atctttttta tgatgtgctt
    36721 gtagattgct tgaaccgact tgaaaaagaa acaaatcgat ttgaagtgac gattacgtct
    36781 gctcatcctc taactgatga acagaagact cgtttgctcc ctttgattga gaaaaaaatg
    36841 tctctgaaag taaggagtgt aaaagaacaa atcgatgaaa gtctcattgg tggttttgtc
    36901 atttttgcca atcacaagac aattgatgtg agtattaaac aacaacttaa agttgttaaa
    36961 gaaaatttga aatagaaagt ggtgttcttt tggcaattaa cgcacaagaa atcagcgctt
    37021 taattaagca acaaattgaa aatttcaaac ccaattttga tgtgactgaa acaggtgttg
    37081 taacctatat cggggacggt atcgcgcgtg ctcatggcct tgaaaatgtc atgagtggag
    37141 agttgttgaa ttttgaaaac ggctcttatg gtatggctca aaacttggag tcaacagacg
    37201 ttggtattat catcctaggt gactttacag atatccgtga aggcgataca atccgccgta
    37261 cagggaaaat catggaagtc cctgtaggtg aaagtctgat tggtcgtgtt gtggatccgc
    37321 ttggtcgtcc agttgacggt cttggagaaa tccacactga taaaactcgt ccagtagaag
    37381 caccagctcc tggtgttatg caacgtaagt ctgtttcaga accattgcaa actggtttga
    37441 aagctattga cgcccttgta ccgattggtc gtggtcaacg tgagttgatt atcggtgacc
    37501 gtcagacagg gaaaacaacc attgcgattg atacaatctt gaaccaaaaa gatcaagata
    37561 tgatctgtat ctacgtcgcg attggacaaa aagaatcaac agttcgtacg caagtagaaa
    37621 cacttcgtca gtacggtgcc ttggactaca caatcgttgt gacagcctct gcttcacaac
    37681 catctccatt gctcttccta gctccttata ctggggttgc tatggcggaa gaatttatgt
    37741 atcaaggtaa gcatgttttg attgtatacg atgatctatc aaaacaagcg gtagcttatc
    37801 gtgaactatc gctcttgctt cgtcgtcctc caggtcgtga agccttccca ggggatgttt
    37861 tctatctcca cagccgtttg cttgagcgct cagctaaagt ttctgatgaa cttggtggtg
    37921 gatcaattac agccctacca tttatcgaga cacaagcagg agatatctca gcctatatcg
    37981 caaccaacgt gatttctatc actgatggac aaatcttcct tggcgatggc ctcttcaatg
    38041 caggtattcg tccagccatc gatgcgggtt catctgtatc tcgtgtaggt ggttctgcac
    38101 aaatcaaagc catgaagaag gttgctggta cacttcgtat cgaccttgct tcataccgtg
    38161 agttggaagc ctttactaag tttggttctg acttggacgc agcaacacag gctaagttga
    38221 accgtggacg tcgtaccgtt gaggtcttga aacaacctgt tcacaaacca ttacctgttg
    38281 agaaacaagt aaccattctt tatgctttga cacatggttt cttggatact gttccagtag
    38341 atgatattgt tcgtttcgag gaagagttcc atgccttctt tgatgctcaa catccagaga
    38401 ttttggaaac cattcgtgat acaaaagact tgccagaaga agcagtcttg gatgctgcga
    38461 ttacagagtt tctcaatcaa tctagcttcc aataagaata gaggtgtcag atggcagtgt
    38521 ctctaaatga tattaaaaca aaaatcgcct caacaaaaaa tacgagtcaa atcactaatg
    38581 ccatgcaaat ggtatcggct gctaagttag gtcgctctga agaagctgct cgcaacttcc
    38641 aagtttacgc tcagaaagtg cgtaaacttt tgacagatat ccttcatggt aatggagctg
    38701 gtgcttcaac taatccgatg ttgattagcc gttctgtgaa gaagacaggc tatatcgtta
    38761 tcacttcaga ccgcggtttg gttggaggtt ataattcctc tattttgaaa gctgttatgg
    38821 agttgaaaga agaataccac ccagacggta aaggttttga aatgatctgt atcggtggga
    38881 tgggagctga tttctttaag gctcgcggta ttcaaccact ttatgaatta cgtggcttgg
    38941 cagaccaacc tagctttgat caagttcgta agattatttc aaaaactgtt gaaatgtacc
    39001 aaaatgaact ctttgatgag ctttatgttt gctacaacca ccatgtcaat acgctaacca
    39061 gtcaaatgcg tgtggaacaa atgcttccga ttgttgactt ggatccaaat gaagcggatg
    39121 aagagtacag cttgactttt gaattggaaa ccagccgaga agaaattctg gagcagttgt
    39181 tgcctcagtt tgcagaaagt atgatttacg gtgccattat cgatgccaag acagctgaga
    39241 atgctgcggg tatgacagcc atgcaaacag cgacagataa tgctaagaaa gtcatcaatg
    39301 atttgacaat tcagtataac cgtgccagac aggcggcgat tacacaagaa attacagaaa
    39361 tcgtagcagg tgctagtgcc ttagaatagg ctctagtcca gctcgtatga aaatgaactt
    39421 aggacctagt tgagctagga accgacagta tcttatatag aataggagaa ggagatgagt
    39481 tcaggtaaaa ttgctcaggt tatcggtccc gttgtagacg ttttgtttgc agcaggggaa
    39541 aaacttcctg agattaacaa tgcacttgtc gtctacaaaa atgacgaaag aaaaacaaaa
    39601 atcgtccttg aagtagcctt ggagttagga gatggtatgg ttcgtactat cgccatggaa
    39661 tcaacagatg ggttgactcg tggaatggaa gtattggaca caggtcgtcc aatctctgta
    39721 ccagtaggta aagaaacttt gggacgtgtc ttcaacgttt tgggagatac cattgatttg
    39781 gaagctcctt ttacagaaga cgcagagcgt cagccaattc ataaaaaagc tccaactttt
    39841 gatgagttgt ctacctcttc tgaaatcctt gaaacaggga tcaaggttat tgaccttctt
    39901 gccccttacc ttaaaggtgg taaagttgga cttttcggtg gtgccggagt tggtaaaacc
    39961 gtcttaatcc aagaattgat tcacaacatt gcccaagagc acggtggtat ttcagtattt
    40021 actggtgttg gggaacgtac tcgtgagggg aatgaccttt actgggaaat gaaagaatca
    40081 ggcgttatcg agaaaacagc catggtcttt ggtcagatga atgagccacc aggagcacgt
    40141 atgcgtgttg cccttactgg tttgacaatc gctgaatact tccgtgatgt ggaaggccaa
    40201 gacgtgcttc tctttatcga taatatcttc cgtttcactc aggctggttc agaagtatct
    40261 gcccttttgg gtcgtatgcc atcagccgtt ggttaccaac caacacttgc tacggaaatg
    40321 ggtcaattgc aagaacgtat cacatcaacc aagaagggtt ctgtaacctc tatccaggct
    40381 atctatgtgc cagcggatga ctatactgac ccagcgccag caacagcctt cgctcacttg
    40441 gattcaacaa caaacttgga acgtaaattg gtacaattgg gtatctaccc agccgttgac
    40501 ccacttgctt caagctcacg tgccttggca cctgaaatcg ttggagaaga gcactatgca
    40561 gttgctgctg aagtaaaacg tgtccttcaa cgttaccatg aattgcaaga tatcattgct
    40621 atccttggta tggatgagct ttctgatgaa gaaaagacct tggttgctcg cgcccgtcgt
    40681 atccagttct tcttgtcaca aaacttcaac gttgcggaac aatttactgg tcagccaggt
    40741 tcttatgttc cagttgctga aactgtacgt ggctttaagg aaatccttga tggtaaatac
    40801 gaccacttgc cagaagatgc cttccgtggt gtaggttcta tcgaagatgt gattgcaaaa
    40861 gctgaaaaaa tgggatttta agaggtgacc tatggctcag ttaactgtcc agatcgtgac
    40921 accagatggt ctcgtctatg atcaccatgc cagctatgta tcggttcgaa ctctggatgg
    40981 tgagatgggg atcttgccac gacatgaaaa tatgattgcg gttttagcag ttgatgaagt
    41041 aaaggtaaaa cgtatcgatg ataaagatca cgtgaactgg attgcagtaa acggtggcgt
    41101 tattgaaatt gccaatgata tgatcacaat cgtcgctgac tctgcagaac gtgctcgtga
    41161 tatcgatatt agccgtgcag aacgtgccaa acttcgtgca gaacgtgcaa ttgaagaagc
    41221 acaagacaaa catttgattg accaagaacg tcgtgctaag attgctttgc aacgtgccat
    41281 taaccgtatt aatgtcggaa atagactata agaaaaaatg aacttgaaaa taccaagttc
    41341 attttttagg ctctttgtca actgtagtgg gttgaaaaaa agctaagctc gagaaaggac
    41401 aaatttt
//
LOCUS       DAVLAQ010000012        40844 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000012 DAVLAQ010000000
VERSION     DAVLAQ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.012"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..964
                     /locus_tag="VXB71_000625"
     CDS             <1..964
                     /locus_tag="VXB71_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0450782.1"
                     /translation="VLQIILPVLTLIVGVNIKTFEQLTLGQIVAISTVSPYFISPIIS
                     LSDNYIQLMLLKGYFLRIEDVFNTKSELIPERVSQDIKFDKKIELKDIWYKYGLFDDY
                     VLKGINVTIKKGETVAIVGESGSGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLY
                     RKIFGAVLQNSTLSYGTLRENLTFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIA
                     EEGNNFSGGQQQMILLARCLLSKPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILI
                     AHRLDTIKSADKILVMHNGEIVEIGTHRELLELGGIYKQLYSNN"
     gene            988..2727
                     /locus_tag="VXB71_000626"
     CDS             988..2727
                     /locus_tag="VXB71_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0450783.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            2778..3545
                     /locus_tag="VXB71_000627"
     CDS             2778..3545
                     /locus_tag="VXB71_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0450784.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            3547..4179
                     /locus_tag="VXB71_000628"
     CDS             3547..4179
                     /locus_tag="VXB71_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450785.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(5108..5521)
                     /gene="ndk"
                     /locus_tag="VXB71_000629"
     CDS             complement(5108..5521)
                     /gene="ndk"
                     /locus_tag="VXB71_000629"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0450786.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(5632..9309)
                     /gene="rpoC"
                     /locus_tag="VXB71_000630"
     CDS             complement(5632..9309)
                     /gene="rpoC"
                     /locus_tag="VXB71_000630"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0450787.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(9342..12953)
                     /gene="rpoB"
                     /locus_tag="VXB71_000631"
     CDS             complement(9342..12953)
                     /gene="rpoB"
                     /locus_tag="VXB71_000631"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0450788.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            13369..13439
                     /locus_tag="VXB71_000632"
     tRNA            13369..13439
                     /locus_tag="VXB71_000632"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13401..13403,aa:Cys,seq:gca)
     gene            complement(13637..14968)
                     /locus_tag="VXB71_000633"
     CDS             complement(13637..14968)
                     /locus_tag="VXB71_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0450789.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRIAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(15197..16021)
                     /gene="endA"
                     /locus_tag="VXB71_000634"
     CDS             complement(15197..16021)
                     /gene="endA"
                     /locus_tag="VXB71_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0450790.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(16060..16248)
                     /locus_tag="VXB71_000635"
     CDS             complement(16060..16248)
                     /locus_tag="VXB71_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0450791.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(16241..17524)
                     /gene="murA"
                     /locus_tag="VXB71_000636"
     CDS             complement(16241..17524)
                     /gene="murA"
                     /locus_tag="VXB71_000636"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0450792.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(17548..17778)
                     /locus_tag="VXB71_000637"
     CDS             complement(17548..17778)
                     /locus_tag="VXB71_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0450793.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17836..18873)
                     /locus_tag="VXB71_000638"
     CDS             complement(17836..18873)
                     /locus_tag="VXB71_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0450794.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18857..19345)
                     /gene="coaD"
                     /locus_tag="VXB71_000639"
     CDS             complement(18857..19345)
                     /gene="coaD"
                     /locus_tag="VXB71_000639"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0450795.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGRDIACYVPESILEEIRNEK
                     KD"
     gene            complement(19335..19874)
                     /gene="rsmD"
                     /locus_tag="VXB71_000640"
     CDS             complement(19335..19874)
                     /gene="rsmD"
                     /locus_tag="VXB71_000640"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0450796.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19939..20931)
                     /locus_tag="VXB71_000641"
     CDS             complement(19939..20931)
                     /locus_tag="VXB71_000641"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0450797.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(21044..21727)
                     /locus_tag="VXB71_000642"
     CDS             complement(21044..21727)
                     /locus_tag="VXB71_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0450798.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(21783..22523)
                     /locus_tag="VXB71_000643"
     CDS             complement(21783..22523)
                     /locus_tag="VXB71_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0450799.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            22557..22835
                     /locus_tag="VXB71_000644"
     CDS             22557..22835
                     /locus_tag="VXB71_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0450800.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22913..23839
                     /gene="yidC"
                     /locus_tag="VXB71_000645"
     CDS             22913..23839
                     /gene="yidC"
                     /locus_tag="VXB71_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0450801.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23914..24708)
                     /gene="pflA"
                     /locus_tag="VXB71_000646"
     CDS             complement(23914..24708)
                     /gene="pflA"
                     /locus_tag="VXB71_000646"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0450802.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24834..26084)
                     /locus_tag="VXB71_000647"
     CDS             complement(24834..26084)
                     /locus_tag="VXB71_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0450803.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(26151..26978)
                     /gene="purR"
                     /locus_tag="VXB71_000648"
     CDS             complement(26151..26978)
                     /gene="purR"
                     /locus_tag="VXB71_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0450804.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(27245..28186)
                     /locus_tag="VXB71_000649"
     CDS             complement(27245..28186)
                     /locus_tag="VXB71_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0450805.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(28176..29432)
                     /locus_tag="VXB71_000650"
     CDS             complement(28176..29432)
                     /locus_tag="VXB71_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0450806.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(29434..30096)
                     /locus_tag="VXB71_000651"
     CDS             complement(29434..30096)
                     /locus_tag="VXB71_000651"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0450807.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(30059..30715)
                     /locus_tag="VXB71_000652"
     CDS             complement(30059..30715)
                     /locus_tag="VXB71_000652"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0450808.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(30726..31604)
                     /gene="rsgA"
                     /locus_tag="VXB71_000653"
     CDS             complement(30726..31604)
                     /gene="rsgA"
                     /locus_tag="VXB71_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0450809.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(31606..32478)
                     /gene="rsmA"
                     /locus_tag="VXB71_000654"
     CDS             complement(31606..32478)
                     /gene="rsmA"
                     /locus_tag="VXB71_000654"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0450810.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(32729..33022)
                     /locus_tag="VXB71_000655"
     CDS             complement(32729..33022)
                     /locus_tag="VXB71_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450811.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(33015..33656)
                     /locus_tag="VXB71_000656"
     CDS             complement(33015..33656)
                     /locus_tag="VXB71_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450812.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(33658..35688)
                     /locus_tag="VXB71_000657"
     CDS             complement(33658..35688)
                     /locus_tag="VXB71_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0450813.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35765..36061)
                     /locus_tag="VXB71_000658"
     CDS             complement(35765..36061)
                     /locus_tag="VXB71_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0450814.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(36381..37280)
                     /locus_tag="VXB71_000659"
     CDS             complement(36381..37280)
                     /locus_tag="VXB71_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0450815.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(37352..37912)
                     /gene="rnmV"
                     /locus_tag="VXB71_000660"
     CDS             complement(37352..37912)
                     /gene="rnmV"
                     /locus_tag="VXB71_000660"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0450816.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37912..38685)
                     /locus_tag="VXB71_000661"
     CDS             complement(37912..38685)
                     /locus_tag="VXB71_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0450817.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38990..39883)
                     /locus_tag="VXB71_000662"
     CDS             complement(38990..39883)
                     /locus_tag="VXB71_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0450818.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(40167..40301)
                     /gene="rpmH"
                     /locus_tag="VXB71_000663"
     CDS             complement(40167..40301)
                     /gene="rpmH"
                     /locus_tag="VXB71_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0450819.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            40709..>40844
                     /locus_tag="VXB71_000664"
     CDS             40709..>40844
                     /locus_tag="VXB71_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0450820.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     H"
BASE COUNT        11846 a         9082 c         7820 g        12096 t
ORIGIN      
        1 tgttttacaa attattctcc ctgttttgac ccttattgta ggtgtaaata taaaaacatt
       61 cgaacaattg acgttaggac aaattgtagc aataagtaca gtctcaccat actttatttc
      121 tcctataatt tctttaagtg ataactatat acaattaatg ttattaaagg gatatttttt
      181 aagaatagag gatgtgttta atactaaatc cgaattaatt ccagaaagag tcagtcaaga
      241 tataaaattt gataaaaaaa tagaattaaa agatatttgg tataaatatg gattatttga
      301 tgattatgtt ttgaaaggaa taaatgttac tattaaaaaa ggagaaactg ttgctattgt
      361 tggagaatca ggttcaggta agagtacatt agctaaaatt ttattaggtt tattagaacc
      421 taatattggt tcaatagaag ttgatggagt agaaaaagaa gaaattggtc aaacattgta
      481 tagaaagatt tttggagcag tgttacaaaa ttcaacccta agttatggta ccttaagaga
      541 gaatttgaca tttggacact ttgtttcaga tgaagaatta atgacaaatc taaattcaat
      601 tggtcttagc aatgtagtta aatctttacc tcttggatta gagacaatca tcgctgaaga
      661 aggtaataac ttttctggag ggcagcagca aatgatactt ttagctcgtt gtcttttgtc
      721 gaaaccttcg gtagttgttt tggacgaagc aacaagtagt ttagataatt tatctcaaca
      781 aattacaact tcttacttaa gtgaaatcgg taccactaag attttaattg cccatcgact
      841 agatactatc aagtctgcag ataagatctt agtaatgcat aatggtgaaa ttgtagagat
      901 tgggacccat agagaacttc ttgaactagg aggcatttat aagcaattgt attcaaataa
      961 ttagtttttg attaaaaggg taaatttatg aagattatga aaaaaaaata ttggacttta
     1021 gcgatattat tcttttgttt gttcaataat tctgttactg ctcaagaaat acctaaaaat
     1081 cttgatggca atataactca cactcagact agcgaaagtt tttctgaatc tgatgaaaaa
     1141 caggttgact attctaataa aaatcaagaa gaagtagacc aaaataaatt tcgtattcaa
     1201 atcgataaga cagaattatt tgtaacaaca gataaacatt tagaaaaaaa ctgttgtaaa
     1261 ttggaacttg aaccacaaat aaataacgat attgttaact ctgaaagtaa taatttacta
     1321 ggcgaagata atttagataa taaaattaag gaaaatgttt ctcatctaga taatagagga
     1381 ggaaatatag agcatgacaa agataactta gaatcgtcga ttgtaagaaa atatgaatgg
     1441 gatatagata aagttactgg tggaggcgaa agttataaat tatattctaa aagtaattct
     1501 aaagtttcaa ttgctatttt agattcagga gtcgatttac aaaatactgg attactgaaa
     1561 aatctttcaa atcactcaaa aaactatgtc cccaataaag gatatttagg aaaagaggag
     1621 ggagaggaag gaataatatc agatattcaa gatagattag gtcatggtac ggctgttgta
     1681 gctcaaattg taggggatga caatattaat ggagtaaatc ctcacgttaa tattaacgtc
     1741 tatagaatat ttggtaagtc gtcagctagt ccagattgga ttgtaaaagc aatttttgat
     1801 gctgtagatg atggcaatga tattatcaat cttagtactg gacaatattt aatgattgat
     1861 ggagaatatg aggacggaac aaatgatttt gaaacatttt tgaagtataa aaaggctatt
     1921 gattacgcga atcaaaaagg agtaattata gtagctgcat tagggaatga ctccctaaat
     1981 gtatcaaatc agtcagattt attgaaactt attagttcac gcaaaaaagt aagaaaacca
     2041 ggattagtag ttgatgttcc aagttatttc tcatctacaa tttcggtcgg aggcatagat
     2101 cgcttaggta atttatcaga ttttagcaat aaaggggatt ctgatgcaat atatgcgcct
     2161 gcaggctcaa cattatctct ttcagaatta ggacttaata actttattaa tgcagaaaaa
     2221 tataaagaag attggatttt ttcggcaaca ctaggaggat atacgtatct ttatggaaac
     2281 tcatttgctg ctcctaaagt ttctggtgcg attgcaatga ttattgataa atacaaatta
     2341 aaagatcagc cctataatta tatgtttgta aaaaaaattc tggaagaaac attaccagta
     2401 aaaaatggta taaaagtgtt aaatatacca aacgtattga gatatgattt gaatatgtta
     2461 caattagaat ataaaaatga acaaagttgg gatagtttca tagataatgt taatttaatt
     2521 gagttggaag agagaattca aactactatt ggaattaaac aaataaacac acacaatatt
     2581 attactattg cccgagaagg gtactctcaa aattatttac ctaacacttc agaaaataca
     2641 tataattcat tacaagtcag tttagttgga gtattactac tttttataag tatggtaaat
     2701 attttatggg ctaaaaaaag taaatgaaaa taaaatttgg agccctctga aaaagtaagt
     2761 cctacagttc aactaaaatg agtcaaaaga tgaatcacct tgatgtaggg gagtttgtct
     2821 tattgctgcc tgaacacctc cgttcagagg aagaacatta taaatctgtt tttgaagacg
     2881 acttaaccag tcgcatatct agtcaagatg aacgacagca aatgactgct acggtaggtt
     2941 atttagaatc aggtcaggat cgttttgtgt ataatacgac ccctatttct taccagcagt
     3001 ttttgaaaga tccaatcatc attgttataa caccccaatc aactggtcca cagtccattt
     3061 tgttttggat agacgcagta cagaactacg ttctctttaa tcaattgtct gatgcccagg
     3121 agcttatcca gagacaaggc attgaaaatt gggtctcaga aatgcaaaca ggttaccaca
     3181 actacatcac attattggat aatatccaga gggaacgttg ggtaatgcta gcaggagctg
     3241 tgcttgggat tgcaacttca atcttgttgt ttaacactat gaataggctc tactttgaag
     3301 aatttagacg tgccattttt atcaaacgca ttgcaggtct caggttctta gaaatccatc
     3361 gcacttatct ctttgctcaa ctgggtgtgt ttttactggg atttgttgcg agtgtatttc
     3421 ttcaggtaga gataggagtt gctttcttag tcttgttact ctttactggt ctatctcttt
     3481 tacagttaca tgtccaaatg cagaaagaaa acaagatgtc catgcttgtt ttgaagggag
     3541 gttaatatga ttgaacttaa acaggtgagt aaatcttttg gagaacgaga gttattttcg
     3601 aatctttcaa tgacatttga ggctggaaaa gtctatgcct taattggttc aagtggtagc
     3661 ggaaaaacaa ccttgatgaa catgattggg aaattagaac cttatgatgg gacgattttt
     3721 taccgaggta aagacttggc caattataaa tcaagtgatt ttttccgtca cgaattgggc
     3781 tacctcttcc agaactttgg cttaattgaa aaccaaagta ttgaagaaaa ccttaagcta
     3841 ggtctcattg gtcaaaagtt gagtcggtcg gaacagcggt tgaggcagaa gcaggcttta
     3901 gaacaggtcg gcctggttta tcttgaccta gataagcgca tctttgagtt atcgggcgga
     3961 gaatcgcaac gggttgcctt ggcaaaaatt atcttaaaga atccaccctt tattctggca
     4021 gatgagccaa cagcttcaat agacccagca acctctcagt tgattatgga gattttgcta
     4081 tctcttcgag atgataatag gctaatcatt atcgcaacac ataatccggc aatttgggag
     4141 atggctgatg aagtgttcac gatggatcat ctgaaataaa aatccttgtt tttaattgca
     4201 cgatgagtta ctgaaatatt atcatgaatc aagaattgga gttaatttag aattgtactt
     4261 tattaatatt gaggtaactt tttcttgata aaggaagaaa taatggagag gaagttagaa
     4321 tgaaaaaatt cgacaattat attattgaga agccttgcga ttctaattca gataaactgc
     4381 aaaaaatctt aataattgaa agtttggtag atgatatttt gcaattttct ctcagaatca
     4441 ataatagtgt aggagagatt ttcctcctac aaccgtttta aaagaaaact atctttattc
     4501 catgttattt tgaggaagat attgtgaaag tcaaagatga tgataaagtt gagtggaatt
     4561 tgttagaatt tcaaaaattt agagcatttt tggcttagta atctgtgttg aaggctcaaa
     4621 acctatggta aaaaagtagc tttgaaaacg tattgcctcc aaagatttag ttaaataatg
     4681 atttaacaca aaaagaaatt attgaagttc tggaaagatg ttgtttcagt attgagaaaa
     4741 ggtgggaaaa acttgcgatt ttcacagaga aaggaagaaa aagtatagaa atatagtcaa
     4801 ttgaaacaag aacaggataa aagaaccttt tgtgccatat ttttctcctt tcgctttaca
     4861 attggattga acacctttat tgtatcgcgt ttggagtttt tttggtataa ccttcgacgc
     4921 acacccgcat agcgggtgtt ttttttgtct cgcacctaac ggagcgagac aaactaatag
     4981 tcacttaatc aaaaaacgca ccatatcaaa aactaaaaag tttgatatca tgcgtcatgt
     5041 cttaaactaa ttgactatac tttctattca aatgagcttt taaccaattg attgagccaa
     5101 tccactctta aaaccaaaga gcaatttctc gcttagctga ctcttctgaa tctgaaccat
     5161 gtacaacatt ttggataatc tcattttctc cagcagcttt tgcaaaatca cctcgaatag
     5221 tgcctggtaa agcttcttct ggacgagttg cacccatcat ggtccgccaa gtttcgatta
     5281 ctttgggacc agaaatgaca cccacaagaa ctggacctga agtcatgaat tcacgaatcg
     5341 gtgggtaaaa actctgacca accaagtcct gatagtgctg gtcaatcaac tcttctgaaa
     5401 cctgtgaacg aaactccaat ttttcgattg taaatccacg ttgttcgatg cgctttaaca
     5461 cttcacccac tagccctctt tttacaccat ctggtttgat gataaagaat gtttgttcca
     5521 tacccgtctc ctttgtcagc ttctttcttt tattttacca catttcgtgg aaaaatggag
     5581 aaagttttca gaagagagaa tgagagaacc ctcgggttct ctcattctct cttattctac
     5641 tgtttcttcc acagtttcaa cggcagtatc cacaactact tctgttgttt cttcatttcc
     5701 ttcttcctct actggaggat taaggtattc ttcttcgttg acagcatgtg gttcaaggtt
     5761 acggtaacgg gccataccag taccagctgg gatgatctta ccgatgataa cattttcttt
     5821 aagtccaagg agatggtctt tcttaccacg gatagctgcg tcagtaagga cacgagttgt
     5881 ttcctggaag gaagccgctg acaagaaact gtttgtttca agtgaggctt tggtaattcc
     5941 cataaggact gggcgacctg tcgctggaac tccacctgcg ataaggacat ctttgttggc
     6001 atctgtaaag tcattgatat ccatgagggt acccatgaga agatctgtat cacctggatc
     6061 catgacacgg actttacgga tcatttgacg aaccattacc tcgatgtgtt tgtcaccgat
     6121 ttctacccct tggctacggt aaactttttg tacttcaccg agaaggtacg tttcaactga
     6181 caagacatca cgaactgcaa ggagacgttt tggttggata gaaccttctg tcagagcagc
     6241 accacgcgct acttggcccc caacttcgac acgcatacga gctgtaaatg gaacgacata
     6301 ttcaccttcg ccagtttcac ccttaacaaa gactttcttg gtacgagttg atgcatcttc
     6361 ttcgatagca gtaacttgtc ctttaacctc tgtaataacc gcttcccctt taggattgcg
     6421 ggcttcaaag atttcttgga cacgaggaag accctgagtg atatcggtat ttgaggcaac
     6481 cccacctgtg tggaaggtac gcattgtaag ctgtgtacca ggttccccga tagattgggc
     6541 agcgattgta ccaactgctt caccaacttc aaccgcatca ccagtcgcca agttgatacc
     6601 gtaacagtga cggcagacac cgtgacgagt gttacatgta aatacagaac ggatagtcac
     6661 ttcttccaca ccagcattga caatttcacg cgccttgtct tctgtaatca attcatttgg
     6721 accaataatc actgcaccag tttctggatg tttaacagtt ttcttagtgt aacgaccgtt
     6781 gagacgctct tcgagagact cgatcatctc ttttccttct gcgatagaac ggatcaagag
     6841 accacggtca gttccacagt cgtcctcacg gatgataacg tcttgggcaa cgtcgaccaa
     6901 acgacgagtc aagtaacctg agtcggctgt cttaagggcc gtatcggtca tacctttacg
     6961 agcaccgtga gttgagaaga acatttccaa taccgacaaa ccttcgcgga agtttgaaag
     7021 gattggcaat tccatgatac gtccattcgg agcagccatc agaccacgca taccggcaag
     7081 ctgtgagaag tttgagatgt taccacgggc tccagagtcc atcatcataa cgattgggtt
     7141 cttaggatct tgattagcaa tcaagcgttt ctcaagtttt tcacgggcag cacgccattc
     7201 agctgtaaca gcattgtaac gctcgtcgtc tgtgatcata ccacgacgga attgtttggt
     7261 gatttgttcg acacgtttgt gtgattcttc aatgatttca gccttgtcat caacgactgg
     7321 gatatcggca atacccactg tcaatcctgc aagagttgag tggtggtaac cgaggttctt
     7381 catgcggtca agtagggcag aagtttctgt cgtacggaaa cgtttgaaga tttcagcgat
     7441 gatatttccg aggtttttct tcttgaatgg agggttgagc tcaagattgc tgatagcttc
     7501 cttgatagct ccaccaagtg gcaagaagta tttagctgga acaccttctg tcaagttggc
     7561 attgtttggt tcttgcaagt atggtagccc ctctggcatg atatcgttga agagaatttt
     7621 accaactgtt gtaagcaaga ccttatgtct ttgctcttct gtccaaggct tgttgaggct
     7681 gtctgttgcg ataccaacac gtgagtggag gtgaacataa ccattgcggt aagccataac
     7741 cgcttcgtca cggtctttga agaccattcc ttcaccttcg cgaccagctt cttccatggt
     7801 caagtagtag ttacccaaaa ccatgtcctg agatggagta actaccggtt tcccatcttt
     7861 cgggttcaag atgtgctcag cagctagcat gaggatacga gcttctgctt gtgcttcttc
     7921 tgaaagtggt acgtggatgg ccatttggtc cccgtcaaag tcagcattgt aggcttcaca
     7981 gacaagtggg tgcaagcgaa gagccttacc atcaatcaag actggctcga aggcttggat
     8041 acccaaacgg tgaagggtcg gtgcgcggtt caaaagcact gggtgttctt taatcacttc
     8101 ttcaaggata tcccagatac gctcatctcc gcgttccacc aagcgtttag ctgctttgac
     8161 gttttgcacg atatcacggg caacgatttc acgcatgaca aatggtttaa agagttcaat
     8221 cgccatttca cgtggcacac cacattggta catcttaaga gttggaccaa cggcgataac
     8281 ggaacgtcct gagaagtcaa cacgtttacc gagcaagttt tgacggaagc gtccttgttt
     8341 acctttaagc atgtggctca atgatttcaa tggacggcta cctggtcctg tgattggacg
     8401 accacgacga ccattgtcaa tcaaagcgtc aactgcttct tgaagcatac gcttctcatt
     8461 ttgaacgatg atacctggtg catttaactc aagcaaacga gccaaacggt tgttacggtt
     8521 gataacacgg cggtaaaggt cattcaagtc agatgaggca aaacggccac catccaactg
     8581 caacattgga cgaagatctg gtgggataac cggaaggatg ttaagaatca tccattcagg
     8641 tttgtttcca gacttgtaaa aggcatccaa aacatccaaa cgacggatgg ctttgacacg
     8701 tttttgtcca gtagcagttt tcaattcttc tttgagttca gcaatttctt tttcaagatc
     8761 tacttgcttc aaaaggtctt ggatggcttc cgcacccatc ttagcaacaa atgaaccata
     8821 accatattcg cgcaagcgct ctcggtattc gcgctctgtc atgatagact tgtgctcaag
     8881 tggtgtatcc ttaggatcaa tcaccacata agccgcaaag tagataactt cctcgagggc
     8941 acgagggctc atatcaaggg tcaagcccat acggcttgga atccccttga agtaccagat
     9001 gtgagataca ggagctttca attcgatatg tcccatacgc tcacgacgaa ctttcgtacg
     9061 cgttacttca accccacagc ggtcacaaac aattcctctg taacgaatgc gtttgtactt
     9121 accacaagca cattcccagt cttttgtagg accaaagatc acttcatcaa agagtccttc
     9181 acgttctggt ttcaaggtac gataattgat tgtttcaggt tttttgactt ctccataaga
     9241 ccatgaacgg actttacttg gagaagctag ggtgatttgc atacttttaa aacgatttac
     9301 atcaaccact atttcttccc tttctattct aagtgaactg cttattcttg ttcagcagct
     9361 tcttctgttg cttccgcttt tgttgctttc tcagcttctt cagcttcaaa ggctgcttta
     9421 gcctcttggg ctgctttttc gcgggctttt tcaaggtcat ctacgtggat gacatcttcg
     9481 tccattcctt catccaagtc gcgaagttcc acttcttggt catcttcgtc taggacacgc
     9541 atgtcaagac caagagattg caattctttg acaagaactc ggaaggattc tggaacacct
     9601 ggttttggaa ttggtttgcc ttttgtaata gcttcatagg ctttcaaacg tccgttgata
     9661 tcgtccgact tgtaagtcaa gatttcttga aggacatttg acgcaccgta ggcttcaaga
     9721 gcccaaacct ccatctcacc gaaacgttgt ccaccaaact gagccttacc tccgagtggt
     9781 tgttgggtaa cagttgagta tggtccgact gaacgcgcgt gcaatttatc atcaaccatg
     9841 tggtggagtt tgatcatgta catgactccg acagaaacac ggttatcaaa cggttcacca
     9901 gtacgtccat cgtaaaggat cgttttggca tcgctatcca tacctgcttc tttaacagtt
     9961 gaccaaagat cttcagaact tgctccatca aagactggtg tagcgatgtg aataccaaga
    10021 gtacgagctg ccataccaag gtgaagctcc ataacctgac cgatattcat acgtgatggt
    10081 accccaagtg ggttcaacat gatgtcgact ggagttccgt ctggaaggta aggcatgtct
    10141 tctacaggaa cgatacgaga gacaacccct ttgtttccgt gacgtccggc cattttatct
    10201 ccgaccttaa tcttacgttt ttgagcgatg taaacacgaa ccaacatgtt aacacctgat
    10261 tgcaactcat ctccatttac acgtgtaaag atcttaacat cacgaacgac accatcggca
    10321 ccgtgtggta cacgaagaga agtatcacgc acttcacgag acttgtctcc aaagatagcg
    10381 tgcaagagac gttcttcagc tgaaagatct ttctcaccct taggtgttac tttacctaca
    10441 agaatatcac cttctttaac ctcagcacca atacggataa tccccatttc gtcaaggtct
    10501 ttgagggcat cttcaccaac gtttggaatt tcgcgagtga tttcttcagg cccaagcttt
    10561 gtatcgcgcg tttctgattc gtattcttca aggtgaacag atgtgtagac atcgtccttc
    10621 accaagcgtt cgctcatgat aacggcatcc tcgaagttgt aaccttccca agtcatgtag
    10681 gcaacgattg ggttttgtcc aagcgccatt tctccatttt ccatagaagg tccgtcagcg
    10741 atgaaatcgc ctttttcaac gacatcacca acttttacga gagtgcgttg gttgtaagca
    10801 gtacctgagt ttgaacgacg gaatttttgg atgtggtaaa catccaatga accatcttca
    10861 cgacgaactt ctaccttgtc agcatctgcg taagtaactt taccatcata ctgagcaatc
    10921 acagccgcac cagaatcgtg ggctgcttgg tattccatac cagtaccaac gtaaggtgcc
    10981 tgaggattaa tcagtggcac agcctgacgt tgcatattgg ctcccatgag ggcacggttg
    11041 gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa cggcaactac ctgttttggt
    11101 gaaacgtcca tgtagtcaac aatattagct ggatactctt ggttgacccc ttggtgacgt
    11161 cccatgacaa tcttctcagc aaaggttcca tcttcattca gacgagagtt agcctgagct
    11221 acagtatatt catcttcttc atcagctgtc aaccaaacaa tttcgttcgt gacaacacct
    11281 gtttcacggt caaccttacg gtatggtgtt tgaacaaaac catatttgtt caagtgtccg
    11341 taagatgaca agttattgat caaaccgatg ttaggtcctt caggtgtctc gattggacac
    11401 atacgaccat agtgagtgta gtgcacgtca cgcacttcat atccagcacg gtcacgagtc
    11461 aaaccaccag gtcctaaggc tgacaaacgg cgtttgtgag acaactcaga aagcgggttg
    11521 tgttggtcca tgaactgtga caactgtgat gaaccaaaga attctttaac tgcagctgtt
    11581 acaggacgaa tattgataat ttgttgtggt gtcaagactt cattgtcctg aacagacata
    11641 cgttcacgga cattacgttc catacgagaa agtcccaaac gtacttggtt ggcaagcaat
    11701 tcaccaaccg cacggatacg acgatttcca aggtggtcga tatcatctac acggccaagt
    11761 ccttcagcca agttgaggaa gtagctcatc tcagcaagga tatctgcagg agtcaccgta
    11821 cgaaccttgt catctgggtt agcattacca atgatcgtta cgacgcgatc tggatcagtt
    11881 ggagcaataa ccttgaattt ttgaagaaca acaggctcag tcacaacggc tgcatcgttt
    11941 gggatgtaga caatcttgtt caagtcgcca tccaaatggc tttcaatgct ttcaatcacg
    12001 ctacgagtca taatcgtacc agcttctacc aagatttctc cagtttcagg gtctaccaat
    12061 ggctctgcaa tggtttggtt gagtaaacgt gttttaacat tgagtttttt attgattttg
    12121 taacgaccaa ctgctgccaa gtcataacga cgtgggtcaa agaagcgagc tacaagcaag
    12181 ctacgtgagc tttcagccgt cttaggctca cctggacgaa ggcgttcgta aatttctttc
    12241 aaggcttcgt ctgtacgaga gtccattgga ttcttgtgga tatctttttc aacagtgttg
    12301 cgaaccaatt cgctgtcacc aaagatatca aagatttcat catcacctga gaaaccaaga
    12361 gcacgaacca aggttgtaaa tggaatctta cgagtacggt cgatacgagt gtaggtgata
    12421 tcttttgagt cgctttcaag ttccaaccaa gctccacggt tagggataac agttgaacca
    12481 tagcccacct taccattttt gtctactttg tcgttaaagt aaacacctgg tgagcggacc
    12541 aactgagaaa cgataatacg ttcaccacca ttgatgatga aagtacccat ttctgtcatg
    12601 attgggaaat caccaaagaa aacttcttgg gtcttgattt cgcttgtttc tttattgatc
    12661 aaacggaagg ttacaaaaat tggtgctgag tagctagcat cgtggatacg agcttcttct
    12721 agcgtatatt ttggttcctt gatttcatat ccaacaaatt ccaactccat tgtgtctgtg
    12781 aagtttgaaa ttggcaatac atcttcaaac acttccttaa gaccgtggtc taggaaagct
    12841 ttgaatgagt cagtttgaat ttcaatcaaa tttggtaagt caagaacttc tttgattctt
    12901 gaaaaactac gacgggtacg atgtttcccg tattgaacgt catgtcctgc caagatgatt
    12961 ctcctttgta aataagttcc aagccttgtc aatcaggctt ttctaatcgt catatggttg
    13021 taaacccctt atcaccgtgt cctcttgacg aattttcaga atctttaagc ctctgttaca
    13081 aatgctcaaa atcttgaaaa aaagcacaaa aagagcagct aaatctgact ttttcagaag
    13141 atttaactgc tgtgagcctt gtctggacaa tatttcagac aaaacctacg acaaatgatt
    13201 acccatatta taccctattt agctagattt ttcaaggggt tttagtaggt ttttggtaaa
    13261 ttttttccca tagaaaactt ggcatcacat tcgaatcacg ctatggtaca aaaaactgaa
    13321 aaaactattg actgaaaatc attttcaagg tataataata aacgttaagg cggtatagcc
    13381 aagtggtaag gcacggctct gcaaaagctt gatcgtcggt tcaaatccgt ctaccgcctt
    13441 ctataacttg atttatcagg tttcaaatga acagaaagcc caatttgaag ggcttttttt
    13501 attttccctc gaataaatac gtataacttt aaaaactttt ggagcgagtt tgtggcagag
    13561 ttctttccat ggcataattc ccttttgaaa tcaattgaaa aaagcttcgt cacgcctggt
    13621 gacaaaagcc tctagtttat tctgtttctt cttctatttc gacttctgtg atttggactt
    13681 ttaccttggt aacacgtcca ttcttcactt tatcattggt taagataaac tgtttgtttt
    13741 ggctaaccaa ttcatagctg agtttctcag tcgttggaat agttcccact cctgtcaaat
    13801 aataaccagc gatggtatca acgtcatcac tttccagttc aacatcaaag taattattga
    13861 aatcattgag ggtcatagtt ccttgaacaa tgtaggtatc ctcgccaatc tgatgaacat
    13921 ctattgctgc tttgtccgtt tcatcatcaa tttcaccaac aatttcctct aagaggtctt
    13981 ccaaagtcac caaaccagcc ataccaccgt attcatccag caagattgcc atttgtcttt
    14041 gggtatttcg cagttctttt agcaagtcat ccacaaaaat agtttcaggt acaaaaagtg
    14101 gatcttgcaa aattctcttc caaacaatat tgtcaaaacc gtccacaaag cctgccttaa
    14161 ggagactctt ggtgtgaatg attccaatta cattgtcctt atccccatca taaaccggga
    14221 tacgagaata attttgtttt aaaatacttt ggataatggc ttgactatca tcctgaatat
    14281 ccaccataaa ggcatccgtt cgaggaacca taacctctcg tgccatcagt tcatcgagcg
    14341 aaaagacacc ttgtagcatc tcaatctcat cagcatccaa tgtttcttca ctatttgtca
    14401 gcatataggc aatttcatca cgggtcatct tttcatccgc atcatcgaat gacataggag
    14461 tcaaatggct caagaaattg gtcgaagcag ctaaaagcca aacaaaagga ctgactagtt
    14521 ttccgatccc aatgataacc ggcgctatac gaattgccaa ggcatccttt agattaagag
    14581 cgattctctt aggatataat tccccaaaaa cgatggaaat ataggtcaaa aatgccaagg
    14641 atagaaaagt tgccacggct tgtgctgttt cgccattccc aagccaagag gcaatcacac
    14701 gtcctagagt attagttaaa ctcgcccctg ataagattgt aatcagggtg attcctacct
    14761 gaatggttga taaaaagtgg ttaggatttt ctagtacctt cagcaggcgg atgtagcgtc
    14821 tgtctccttc ttccgccttt tgttcaactc gggcacgatt aagagaaacc atggccattt
    14881 ctgtggctga gaaaaaggca tttaataccg tcaagataaa caataaaaca aattgtagca
    14941 acaaattctg actacttggg tcttccatag ttcttctcct aaaatagtat cttatccttt
    15001 attatatcac aaaatttaat ccaatacata ttattttttc ttaccgtaac ttctcaaagt
    15061 aacttccatc tctctcccaa aactggaagt tagttttaga agttgctatt ttttcttagt
    15121 acctgttcta gccctgctta aactagtaaa aagaactcct acatccataa gtgacatagg
    15181 agtttaggct tatcttttac tgagttacag ttacttctcc agttcggtaa tccagttgaa
    15241 gtcccttttg aacattggga actagaacat tgaattccaa ttctccatcc gaagacttgg
    15301 cttcaatctg tgaagctgag ggaactaaat cctcgtttga agcgtagtaa agggttacac
    15361 ggtaacggac acgcttgttt tggtccaagg ctttacgcac cttgctttca tagtagtttt
    15421 gaccagtcga atactcggct tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt
    15481 taggattgct tgttgaggca tcaaaaccat ccaaaccacc gattaaggca tagcctaaca
    15541 aatgacctct atcgactgca tgggtataag agccctttag attcttgacc tgatgccaac
    15601 ctggaggagt ccaagaagtt gaaccattcc cagtttcttt acgattcttg tactgacgag
    15661 tggccttaga caagagggca ttagctacgg ttggaacagt ttccttgccc actgtctttg
    15721 ttttattgtc agcgtagggc ttacttgaaa ccttggcatc tagatttgtt ttattaccat
    15781 tgacgataaa agcacctgag ccattccact ccagactccc ctttatttga ctcttgactg
    15841 cgtctgttaa gacactctct gccaatgctt gactaggagc ttcagacgct tgttttttct
    15901 gactaagatt ggttttggga ctattaggtg ccgacggcat ctgcttgata taatagctcc
    15961 ctgtagacaa aagcaataac actagcagtc cgattagtgt ctgtcttgtt tttttgttca
    16021 tatttctcct tatctttaga aaaaggctgg ttctccagcc taatttcctg taaatttatg
    16081 aatcaattcc tgccattttg ctggagacag gatagcccat ggatcttgac ccttgcccaa
    16141 gattccataa cctaccatta aaccgattcc tagagccaga gtacctaaaa tcagtactat
    16201 gatgactaaa agtaaacgct tgactacgta gcttgatttc ttattcatct tcatcacttg
    16261 cctcaatccg ctgaatctta gcacctagct gcgccaactt ctcatggaaa ccgtagtaac
    16321 ctctatccaa gtgaaccaat ttaccgacca cagtttctcc ctgtgctacc aaacctgtca
    16381 aaatcaaggc tgcactggca cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct
    16441 gtccaccaac aatacgagct gtatcacgga taatctcaga atgcaagccc atgcggcgca
    16501 tctcttctag gtgttggaaa cgattttcga aaactgtctc caccatggtt gattcgcctt
    16561 ttgcaactgt catcaaggct gtaaattgag cctgcatatc tgttggaaat cctgggtggg
    16621 gcaaggtttt cacatgaaca gcttttagat tttctagttg agaacgaaca cgaattcctt
    16681 cgtcttcttc aattacttca acacccattt caagtaactt ggcaatcaag ggacggttgt
    16741 gctcccagac agcgtctcga atcaagacat caccaccagt catggcagca gctaccataa
    16801 aggttcctgc ttcgatacgg tcttggacta cattgtgagt cgtaccatga agtttctcaa
    16861 caccagtaat ggttatagtc tctgtaccag cacctttgac cttggctccc atttcattaa
    16921 ggagaatggc taagtcaaca atctcaggct cacgcgcagc attctcaatc actgtcaccc
    16981 catcagccag agtcgctgcc atcatcaagt tctgcgttgc accaacactt ggaaagtcca
    17041 tatagatatg agcgccatgc aagcgttctg ccttggcttc gatgtaacca gctgtctgac
    17101 taatcttaac ccccatagct tccagacctt tcaaatgaag atcaatagga cggctaccaa
    17161 tcgtacaacc acctggcatg gataccttgg catgacccac acgggcaagg attggcccta
    17221 atacaacgat ggaggcgcgc atcttgctga catacttgta aggggcttcc tcagtgatgt
    17281 cgccagtagc atccaccttg acaagatgag cttcctcatc aaagtcaacc ttggcattca
    17341 aaccaccaac tacctgattc ataataaaga catccgacaa aatcggaaca ttctgcaaga
    17401 cggtctttcc ttcacttgct agaatagtcg ctgccaacaa gggtaagact gcattttttg
    17461 ctccctcgat cgtcacgctt cctaccagac gattatcgcc accttgaacc acaattttat
    17521 ccatactcgt ttcctttact cttgatttca taataatcct ctaagcgctt cttgccacaa
    17581 atgatacagg ctaataaaga aagaactcag gatgtagcct atgacaatgc taaaaaaggc
    17641 tactaataaa cgaacttttc ttgtattctc atctgtcact tttaaaacct tctcccatct
    17701 aacaagatcc tttaaaaggt aaaaactcac ataaataaag agcatatgac tacttagagt
    17761 gaataataat tgaaccattt gactattata ccatcttctc tgtttgtgcg ctagtttgga
    17821 aacttcactc aaaaattagg gattgttttt caagtaatca atcgcatctt gtagggtttt
    17881 aacgggcacg attttcatat ccgtcttgat tgttttagcc gcttctaggg ctgtttggta
    17941 gttgtttttc gcgtccggat gcgccttttg ttcttcttcg ctaacagggt tatcaggagc
    18001 aaagaaaata gcagcacctg ccctagccga agctacaacc ttcttatcaa tacctccaat
    18061 gtctcccaca ttaccatcgc ggtcaatggt acctgtaccg gcaacaatac gaccattacg
    18121 aagatctggg tgagctattt gagtatagat agctagacta aacatgagac cagcacttgg
    18181 accgccaata ccagctgttg aaaagctaat tgggacattg ctgattacct ctgtacggtc
    18241 aatcaagccg attccaattc catttttgcc attttccaag gtgataatct ttccttctgc
    18301 agacttggtt tgcccatcct cttcataggt gaccttgacg gaatccccta atttttgaga
    18361 actgacgtaa tcaatcaagt ctttggaact atcaaaggtc tgatcattga ctgctgtgac
    18421 tgtatcagag atattgagaa tccctttaaa ggttgaatta tccgtcacat tcaaaacata
    18481 aactccaaag tacttgagtt cgatatcctt accagctgtt tttagtcctt gatacttggc
    18541 catattttgc gatgtttgca tgtagaattg attgattcgc ataaattcaa catcggaaga
    18601 accacctgta gtctcctgag cactacgaat atctgtaaaa ggtgtcaacc aagcataaat
    18661 catatgagct aaagtggcat gttgaacacc aaccgtaacg aattgatagg caccagcttc
    18721 cttatcttct gtgtcattta ttttaaggac ttggcgaata tcttccgaac cacctggaac
    18781 ctctatataa taaggcaagg gcactacaaa tgccaagaaa gtcacaatca aggccgcaat
    18841 gacgtataag ggccatctaa tctttttttt catttcttat ttcctccaaa atactctcgg
    18901 gaacatagca ggcaatatcc cgaccaaact tcaaaagctc tctaacgcct gatgaactga
    18961 tatagagatg ttcaggtcga ctatgtaaat aaatagtctc tatatcagaa gacagctgat
    19021 gattgtagta atcaaaactg gcttcatatt gcaaatccga cgcattcctc aaaccacgca
    19081 ctagacaagt agcacccaat ctttttgcaa catcgaccac caattcatca tgagaagcca
    19141 cgacttcaac attttccaaa tgtcccaaag ccttttctag cccccgttta cgattttcaa
    19201 gagggagaaa tccttgtttg tggggattaa aaaaaatacc cacataaagc ttatcaaaaa
    19261 gtctgctcgc ccgttcaatg atatccagat gcccatttgt catcggatca aatgagcctg
    19321 tgaataagcc aatcttatct gacatagact gtcaccttac taattccata aatcttttcc
    19381 ttccagatac ccagacaggc aatttcttct ggaagttcaa cggctttatc cgtctcgcac
    19441 acaaccataa catcttcaga aaaaagctct ctctcagcca ttttttcaat atctgctacg
    19501 atttgttcct tggcataggg agggtctaag aaaacgaggt caaattcccc agatacctgt
    19561 tccaatgccc tttctgcatc catctttagg agttgaaatt ttccaacttc cttggtcatc
    19621 tggatatttt cagccacgat ggtctgagcc ttacggtctc gctccaccaa aacagcactg
    19681 gacatgccac gcgatactgc ttcgatagat aaaccaccac tacctgcata aaggtccaag
    19741 actcgtccca cttcaaagta gggaccaatc atgttaaaaa tggctcccct aaccttatcc
    19801 gaagtaggtc ttgtcgtctt gccttctagt gtcttgaggg gacgtccccc atagattcct
    19861 gatacgattt tcatactgtt tattatacca aattatagac aaaaagagaa agaaaaccga
    19921 accttgcggt tcgattctct acaaaatatt ttcgtaagta tcgcggactt cttgaggcca
    19981 aacacttgtt tgcacttctc cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga
    20041 ttgtccaatt cctccaccga ttgtcaatgg gaatagacca ttcaacaaag acttgtgcca
    20101 ttccaattcc aagcggtctt catcacctgt aatttccacc tgacgtctaa gagtttcttc
    20161 atctacacga attcccatag aagacaactc aaaggctcca cctaaagact cattccagac
    20221 aagaatatca ccatttagac ccttgtagcc attctcagac tcgcttgtcc agtcatcata
    20281 gtctggtgca cgtccatcgt gcggtttacc atctggcaac tcgccaccga taccaatcaa
    20341 aaagacggct ccaaattctt tacaaatcgc attttcacgt tctttcggtg tcaagtctgg
    20401 gtagcgttct accaattctt ctgtatggat aaaggtgatt tgttttggca agatagactc
    20461 gatgtcatag cgggcttcaa cagctagctc agtcaggcga atagccttat aaatcttctc
    20521 aactgtttct tttagataaa cgatgttacg cttaccattt gggataacct tctcccagtc
    20581 ccactggtca acataaacag agtgggttgc atccaaggaa tcctcatctg gacgaagggc
    20641 tttcatgtgg acaaagagac cctctccttc accaaagcca aaacgagcca aggtgtggcg
    20701 tttccattta gcaagtgagt gcaccacttc ataagtagca tcagggattt ggagaacctt
    20761 gaccgatact ggattttcca caccagacag gttgtcctgc attccgtcac cgaccttact
    20821 caagatagga ccttgaactt cgacaacttc tagcttatct ttcaaatact gggtaaaagt
    20881 gtttttgaca aaggaaattt cttcttgttg atggataaaa cttttcttca tagacaactc
    20941 ctcaaaaatt taataaacgt attatacacc tatttccaag aaaagaaaag agaaaattta
    21001 aaaaaaaatc agtgtcactc aaaacactga tttcatagac cttttagtca ttgcgaccaa
    21061 agatacgtag aatacttagg aaaagattga taaaatcaag atagatgctg agagccattg
    21121 acaccaccca gcctgtcgct acacgacctt gtgattgttc ataggcgagg cgaatctttt
    21181 ggttatccca agcaatcaac cctgaaaaaa ccaaaaccat ggctacgcta atcatataat
    21241 caaagaagcc actagccaag aaaatattga ctaccatagc aatcagtaaa ccaatgagag
    21301 ctgccatcat tgctcgacca atcccactca agtctttctt ggtaaaaata ccaactgccg
    21361 ccatgacaaa gaagagaagg gcgctcgata caaaggcaga taaaactgta cccggagtat
    21421 agaaagccac cacaaaacta agggtaaagc cgtttaaaac ggagtaaagt aaaaatactg
    21481 gaagagcagc tggactattt cttgaagcca tgctactggc aacgaaaacc aaagccaact
    21541 ccgcaaaagt agcaatggtc aaccagagac gcccctgcat caaaaagtaa accaactgag
    21601 actgaaagac cgtcaacata aggcctgata ccaaagcaga tagtccgatt cccagaccaa
    21661 caaaggcata aaccttagcg taaaattgat tgagacctgc acggtcatgt ataatagtgt
    21721 gattcatcca tttctccttt tctgtgaaca tctttccttg attataacaa aaaaagttaa
    21781 aattagctta aatggaagat taaaataccg gctgcaaccg caacattcaa actctcggcc
    21841 tgccccttca tgctaatatg gaccaactgg tctgcacttt cagccataag gggactaatt
    21901 ccttgaccct catttcccat aactagtaca aaattttcta tagaaggcag ttctctgtaa
    21961 tcaacagaat ctttagatag ggttgttgct agcactggga tagctacctt tttagtttcg
    22021 tcaagaagcg cttgactagt catccggtaa atgggcagat ggaaatgact accttgcatg
    22081 gaacgtaggg ttttgagact gtagatgtct gccgacttat ctgaaacaat cactcctgta
    22141 aaacctgctg catccgcagt tcgaatgata gttcctacat taccaggatc ttgcacatct
    22201 tccaaaaaca agaacttgcc ctgactcaaa tcagcttgtc ctacttcttc tttttgaacc
    22261 acggcaacaa ttccctgtgg agtctgagaa tccgccaaat ctagcaaaat atcctctgac
    22321 acccagacag tttgcgaaaa agtagctaac tgatctcgat aattttctag ggcaaagatt
    22381 ttctcaatcg tcactccagc ttggacagct tcttcaaaca agtgccagcc ttcaatcaag
    22441 taggcagact tgcggtattt tttttggcgt aatttcttgg cattttttac cacagaattg
    22501 gcttttgagg ttataatagt catagaaata ttataacaca atcaaagggg tttggtatgc
    22561 aaaaggttag aatgattgcc caaggtaggg tacagggagt cggctttcgt tggggtgttt
    22621 acagcttggc acttgaaatt ggtggcatca caggtcgagt atggaataac gacgatggca
    22681 cagtggaaat cttagcccaa gcagactcat ctgctatcat ggcaaaattt atccaagaaa
    22741 tccgaaaagg accgacacct ttttcaaaag taagctactt agatgtcaaa ctaagcaact
    22801 ttcctcccta ctctgacttt aaaatcgcaa attaggtctc cagaactatt gtatattttg
    22861 taaaaaaaca gtagaataga aaggtataat ttttaaagaa ggaataaaaa cagtgaaatc
    22921 tattaaacgt tttgcactct cagctatggg agcggctatg ttgcttgtct tgactggttg
    22981 tgtcaatgtc gataaaacca caggtcagcc aacaggattt atttggaata ccatcggagc
    23041 ccctatggct gaagctatca agtacttcgc tactgataaa ggtctaggct ttggtgtcgc
    23101 tatcatcatc gtaaccatta tcgtgcgctt gattatcttg ccacttggta tctaccaatc
    23161 atggaaggca acgcttcact ctgaaaagat gaacgccctc aagcacgtcc ttgagccaca
    23221 ccaaacgcgt ctcaaagaag cgactactca agaagaaaaa ctcgaagccc aacaagctct
    23281 ctttgctgct caaaaagagc acggtatcag catgtttggc ggtgtaggat gtttccctat
    23341 cctccttcaa atgcctttct tctctgctat ctactttgct gcccaacata ctgaaggggt
    23401 tgctcaagca agctacctag gcattcctct aggttctcca agtatgattt tggttgcctg
    23461 tgctggtgtc ctttactatc ttcaatcgct cctttcactt cacggagtag aagatgaaat
    23521 gcaaagagaa caaatcaaga aaatgattta catgagccca ctcatgatcg tcgtcttctc
    23581 cctcttctca ccagctagtg tcacacttta ctgggttgtc ggtggtttca tgatgattct
    23641 ccaacagttt atcgtcaact atatcgttcg tccaaaactt cgcaaaaaag tccgtgaaga
    23701 actagccaag aacccaccaa aagcaagtgc tttctctaaa ccaagtggac gaaaagacgt
    23761 tacccctgaa caaccaactg ctatcacaag caagaaaaaa cacaaaaatc gcaacgctgg
    23821 aaaacaacgt tcgagataag aagaaaaagg cttagctgat ttgctaagtc tttttgcaaa
    23881 tcaaaagccc gatgtttcca tcaggcttct tttctatcca tgtacacgtt tcatataatc
    23941 ttgataactt tcggtatcca tgagtttttt agcgttcttg acgcgatctg ctgttggtgg
    24001 tttgactcct tcgagggaat atggaattcc aagttcacgc cacttgaact cacccatggt
    24061 gtgataaggt agaatttcaa acttatcaac atttttgagg gtcttgacga acttaccaag
    24121 ttcaatcaag tcatcatctc tgtctgtcaa tcctggaact agcacgtggc gaatccagac
    24181 aggttttcca atatctgata gatactgggc acaagccaag atatttttat tggtttgtct
    24241 agtgacaatc ttgtgctgtt cttcgttgat ttccttgata tccaaaagaa ccaagtcagt
    24301 gacagccatg agtttgtcaa acttctcaag gtaacgtggt ttattacgga aaggaagagc
    24361 acaggtatcc aaggtacagt ggattccttg ttccttagcc ttggtgaaga gagcaatcag
    24421 gaaatcaatc tgcaagagag cttctcctcc actgactgta atcccaccct tatttcccca
    24481 gaaaccacgg tagcgcaagg cctctgtcaa gacatcatct accgtccgtt cacgtgactt
    24541 attggactcc atagcccaag tgtctgggtt gtggcaatac tggcaacgca tgtgacagcc
    24601 ctgcaaaaag acaataaagc gaataccagg cccatctact gacccaaagc tttctgtcga
    24661 atgcaccatt cctgtcactt gtccataatc aattgtttct tcagacatat cgttaccttc
    24721 cttgaaaacg ttttatagtt ttattatatc acgacttgaa ggaaaaacaa gatttttgcc
    24781 tattttttag aaagcaatct gtttttcaat ttcattttca atctattatc agattattct
    24841 tcaaaatcga agccatataa ggttgcaaaa tagtcctcag ggcgctctgc acggcggatt
    24901 tgacgggctt taccttcttc ggtatagagg atttccgcag aacgtaattt ggcattatac
    24961 tggtagccca ttgaaaatcc gtgggcacct gtatcatgaa ttaccagcaa atcaccgatt
    25021 tctgtatgag gcagttcgcg attgactgca aatttatcat tgttttcaca gagtgaacca
    25081 accacatcta ccgcttcagc tggtccatct ggatgggtca cgttgctaat atgatggtaa
    25141 gctccgtaca tagctggacg catgaggttg actgctgagg catccacacc tagataggta
    25201 cggtaggttt ccttcttatg agtcactctt gtgactagag caccgtgagg tgccagcata
    25261 aaacgaccca attcggtgaa aatcttgacc tgaccaagac ctgctgacgt aagaacttct
    25321 tcatacacct tacgaactcc ctcaccaatc aaggcgatat cgttcggctc ctggtctgga
    25381 cgataattaa caccaatacc gccagaaaga ttgataaagt ctagccaaat gcccaacttt
    25441 tccttgattt caacagccag ttcaaagagc tgacgagcca actctggata atagagatgg
    25501 gtcacggtat tggacgctag gaaggagtga atcccaaaag tcttggctcc tttttccttc
    25561 aagatagcaa aggcttcaaa gagctggtcc ttggtcatgc caaacttagc ctccccagga
    25621 ttgtccataa tgtctgtccc cagttcaaaa acgcctccag gattataacg acaagagatg
    25681 atttctggaa tgcctgctac tctctccaga tgttcaatat cttcaaaggc atccaagtta
    25741 atggtcgcac ccaattcacg tgcataggcg tattccttgt ctggcgtgtt gttggaagag
    25801 aacataatct cagaacccag aaagtccagt ttatggctca tcaaaagctc tacataacta
    25861 gagcagtcca caccacaacc ttcttcttgg agaattttca aaatagctgg agttggagta
    25921 gccttaactg caaaatattc cttaaagccc ttgttccacg aaaaagcttg gttgacggct
    25981 cttgccttct cacgaatccc cttctcatca tacaagtgaa agggagtcgg gaactcggca
    26041 acaatcgctt ctaactcttc tctattgata aatggtgttt tcataagctt ccttctattc
    26101 tgtttgcaaa gaaaggctgg gacaatcgtt ccaaccttta gttctatctc ttatttatct
    26161 tcgtcaaaga tattgccaac ctcaacatcg atggcttggt tcttgacatc aatattagtt
    26221 accttcaaga gtgacttgta gtcaaactgc ttttcacgtt cttcttgggc attgtccgca
    26281 aagaccgcta cacctgccag ttctgagtcg aactcgcgca agagactaat cataccgttg
    26341 accgttccgc cacctttcaa gaagtcatcc acaatcaaga cacggctacc tgccttaaga
    26401 ctacgttttg aaaggaacat tttctcgata cggtcaccac ttgaacctga aacatagttg
    26461 acgctaacag ttgaaccttc ggtaattttc aggtcacggc gcacaatgac aaaagagaca
    26521 ttgaggacat tggcaactgc atttgcaagt ggcacaccct tagttgctac ggtcataacc
    26581 gcgtcaattt tttggtccat aaagcttttg gcaataatac gaccaatatt tttcaagatg
    26641 gctggtgtgc taagcaaatc agacagatag atataaccac ctggcaagat acggtcactt
    26701 tctgacaact tggtacgcaa gtcttcaacc atttccttag catcctgact cgaaatagac
    26761 ggtgtgaaga tgacacctcc gccagcccca gtcactgtct ggatatgacc gatttcaatt
    26821 tcctcaaagg cgcgtttgat aatgacgata tcttctgaga tggatgattt agcagactca
    26881 tacttttcag caaaagtatt gagactagtt agtttataag gattattaat caaatagttg
    26941 gaaatgacaa ccatccgatc acttcttctt aatttcattt ctatttccta ttccattttt
    27001 attcaaaaaa tcaaaaagca aactagaaag ctggtcgctg gtggttcaaa acactgtttt
    27061 gagattgtca atagaactga caaaccctgt aatatacctg catatataca tacgacaagg
    27121 cgatactacc ctagtttgaa gagattttcg aagagtattc atttttgtct tttacttatt
    27181 ataccatatt cacataaaaa aacgaacatt cttatcctaa aaaatgctca tttttcttaa
    27241 attattaatc taaatctggt ttatagaagg aacgattatc catagcgaag attttattgg
    27301 tcatctctcc tttatccacc aaagcaagag ctgttgacat catcatcatg cttgcatcca
    27361 gattgtcaat catatggata atctctgctt ccataatgcg tggacggact gggcttccat
    27421 actcaagcaa gccgtggtga ctgaggatga catgacgaag caaaacgact tcttccttgg
    27481 tatcatcgat gccgagttcc ataactgtct tggtaatttc gctatcaatg agagcgatat
    27541 gtccaagaag attacctcgc actgtgtact ctgtctggtc tggccccgtc aactcgatga
    27601 ccttagctaa gtcatgcaac ataatccccg catagagcag gctcttattg agctgaggat
    27661 aaacttcgct aatagcgtct gccaaacgca ccatggtcgc cgtatgatag gccaagcccg
    27721 tttcaaaggc atggtggttg gtcttggcag ctggatagga gtagaattcc ttatcatact
    27781 tggtgtagag atttcggaca atccgttgcc agacaggatt ttcaattttg aaaatcattt
    27841 gcgacatgta gtcacgaatt tccttgacat caactggtga cttgaccttg aaatcggctg
    27901 ggtcattggg ttcaccagct tgaggcaggc ggagagtaat ttgattgact tgaggggtat
    27961 tgttataaac ttctcggcgt cctttcatgt ggacaacctt acctgcggta aaggcctcaa
    28021 tgttatgagg ttgggcatcc cagagcttcc catcaatctc gccactatca tcttggaagg
    28081 taaaggctag gtagtttttc ccagctcgag tttgcctcag gtcagctgat ttgattaggt
    28141 aaaagccttc aaatagctca tcttttttca tgtgactaat cttcatattc ttcctcattt
    28201 tcttgaaaat ggagtagatc aagcgcaggc tcgccttctg acaactcaat gtgacggagc
    28261 gtccgctcga tagctatggt acgacggttt aataattcat caatattgcc agaggcatgt
    28321 tggagatgtt tttgtgcctt gaccagaata ccaccaaact tgccaaactc ggtcttgaca
    28381 ctggcaagag tcttgctgat atggtcggca ctcttttgga tattaagggt cttgaaacca
    28441 actgataggg agttaagaag ggctgatagg gtacttggtc ctgcaacgat aatctgttct
    28501 tcccgtctca aatcatcaaa gaagaccgga ttgcgcacaa tctctgaata aagaccttct
    28561 gtcggaacaa acaaaactcc aaaattggtc gtccgaggcg gtgctatgta cttgctcttg
    28621 atatccttgg caaagcgctt gacgcttgct aggagtgact tacgacagcg ttcaatctca
    28681 tccttgtcac ctgtctcata ggcttcttcc aagcggtaat aatctgccag tggaaactta
    28741 gagtcaattg gcagatagac gtattcttgg tcgccttgtc cgggtaactt gatggcatac
    28801 tccactcgtt cactagagtt ttcaaccgtt gcgtattctc gttcgtactg ggcaggtgtc
    28861 atgatgtctt caataatttg ccccagttgc aattctccca gaatccctcg cgtcttggtt
    28921 ccagagagaa ccttgttaag agctccgaca tcacgggcaa ctgtctgcat ttctccaagg
    28981 ccacgattga cagactccag ttgtttagaa actgtctcaa aggaagcctg taagcgtgtc
    29041 tgcaaggtct tttctagttt ttcctcgacc gtctggcgca tttgttccaa acgttgctca
    29101 tttgattcct gcaaggcttg gagacgttgg tctgtcttgt ctctagtttg gaggagatta
    29161 tctgtcattt cttgacggac ttgggtcaga ccttggtgca attcaatccg cacttcttgc
    29221 aaacggtcgc tgacaaccac ttccaaatct ttttggtcta actggctggc ttgtctggct
    29281 tggtcaaagc ggtaatccaa ctggtctgac aaatgatctg cctgatcctc caagctctta
    29341 cttaagtgtt tctcctgcct atcctgcctt tgccaaatca gaaagagacc agctaggttg
    29401 gcaattaata atagaataag taaactttcc atcctacctc ctgtccttgc tatgcagtac
    29461 gaccacataa ccatctgggc aagttaccga cacttcccta tctatatatt cgttagaagc
    29521 gtacactttt ttaaagaaaa aattttcctc tgtcaactca tacttggctc caagaatagt
    29581 cagctggcta tcccgaactg gcataaaggc tagatagtcg tagtctgaac gaggttctag
    29641 ctgactggtc ccttctggac aataagtaat caagttttgc ccatcctcaa tttctatttg
    29701 atgcatatag ggtgccaact taggattgct aggcagaaag acattggcca acatatggtc
    29761 aatacggcca cccaaggcac cgaaaatagt aacctgagcc tgaggatttt tctcaaagat
    29821 ggttaagaga gccaattcca aatcggtatc atctttttct ggtcgggctt ggacaaaatg
    29881 ctgggcacgt ttttgaatca cctgtcgctc ttcttcggtc acagaatcaa aatccccaac
    29941 tgctagagca agaagcaagt cttcttccaa gacccagagc gagcctcgat ccaccccaac
    30001 aaaagcatca aaatctgtcc gataatgacc gcggtctccg cctgcaaaaa cggcaaccct
    30061 agtccagttg ttttctgaga gtttgtactc gctcattgac atctccctta aagacatagg
    30121 aacctgctac aaaaacggtc gcaccagctt ctttggcttg ggcaatagtt tggtcatcaa
    30181 tcccaccatc cacttcgatt tcaaagttca aacctttttc ctcacgaaga gcaaccaact
    30241 cacgaacctt atccatggtt tctggcagaa aggcttgccc accaaaacct ggattaaccg
    30301 tcatgactaa aacttggtca actagatgaa ggacgtgctt gatggcttca actgatgtgc
    30361 caggattgat aacgactgaa ggcttaactc cgagtgaacg aattttttgg agggcgccat
    30421 gaatatgagg cgttgcttct acatggatac tgatgatgtc tgcacctgca cgcgcaaaat
    30481 cttccagatg atgctcaggg tttgacacca tcaagtggca atcgaaaacc atcttactat
    30541 gaggacgaag gctctcgacc acacctgcac caaaactgat ttgcggtaca aaatgactgt
    30601 ccatgatatc gatatgggca tattctgccc cagttgcttc tagacgtttg atttcacgtt
    30661 caaagttggc ataatctgct gccagaattg acggagcaat cttgtattga gacataggtt
    30721 tctccttatt ttggaatttt tttgctgact tttttatagg tttctctacg attttcaatt
    30781 tcactaagga attgcaggta attgtcaaaa cggaaggttg caataacacc ctcttcaaca
    30841 gctggtttga cggcacaaga cggctcatgg gtatgggtac aagtacggaa cttacaatct
    30901 cggctaacag tagcaatctc tggaaaggcc tgattgaggt cttcagccct tgatacttca
    30961 tagtccagag atgaaaagcc tggtgtatct gcgattttac ccccgttgag attgtaaaaa
    31021 ctaacagctc gagtggtatg gcgaccgcga cctagactgt ctgaaatttc tcccgtttca
    31081 agattgaggt ctggtgcgat tttattgaga agagttgact tcccaacacc tgtctgcccc
    31141 ataaagaccg taaccttgcc tgttaacaaa gacaggagtt cctctttact ggtcacaaag
    31201 tcatagccga tgtcaccata ggtctgctgg taaaaatcca gttctcccct atcttccaac
    31261 aaatccattt tggaaatata gacaatggga tggatgccct tgtgctccaa aagaaccaag
    31321 aaacgatcca gcaaattgct gttaaaatca ggttccttga cggacatgat tactacagct
    31381 tgatcgatat tgacaatagg cggacgaacc agactgtttt tccgttcgtg aattttgagg
    31441 atatagcctt ctgaattttc ctcggcagag aaatctaccc agtccccaac ataaggggta
    31501 tggccttttt tacggaaatt cccacgcgcg cgtgtttgat aaacctggcc atcactctcc
    31561 acatagtaga aacctgccaa ggctttaatg atttgtccct gcatcttaga gtccttgccc
    31621 tttaagtgcg tctgctagac cggcaaattc tgccaagctg agagcttccc cacgcacact
    31681 tggtgacaag cctgcctggt ccaaagcctt ggtcagcttg tccttgacct cttcagtctt
    31741 accaaagtaa cctgtcaagt tattccacaa ggtcttgcgg cgatgggtaa aactagcctt
    31801 ggaaacctta aagaaaaagt tctcatcttc tactgctacg gctggctctg gacgacgcac
    31861 cattttcaag atggctgaat ccacatttgg cgctggcaca aagaccgtac gaggcacgat
    31921 aaaggcaacc ttggctgtca tgtaatactg cacggcgata gacaagctac cgtaagcctt
    31981 ggtgttaggc tgggctgaaa tgcggtccgc tacttctttc tgcatcatga ccacaaactc
    32041 acaaaaagga atgccactct caatcaagtg catgagaata ggcgtcgtga tgtagtaagg
    32101 caaattagcc actaccttga ttggcaggtt aggattttta aaattttgga tatgttgcgc
    32161 caaatcaacc ttgagaatat cttcgttaac tacggtcaca ttatcaaaat cacgcagagt
    32221 atctgccaaa attggcatca aacggtggtc aatctcaaaa gccatgactt gggctgcacg
    32281 ctcagccaaa aattctgtca aggcaccaat acctggcccg atttcgatga cattgacctg
    32341 atcatcaatt tcagccgtat ccacaatttt ttgaaggata ttggtatccg tcaagaaatt
    32401 ttgcccaaag gactttttaa aggtaaaacc gtgacgctcc aacactgcct tggtcacgct
    32461 ataatctgca attctcatct attctctttt ctattatctg ttactactat tgtaacacat
    32521 tccccttgta ttttgggaat gaaaatcata ccaaaaaact atctttcctc atgaagaaag
    32581 atagtcttgg aaatctttaa agagggactt agtgcttctc tcgaaacata cgttcatact
    32641 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtactcaagt acagcctgcg
    32701 gctagcttcc tagtttgctc tttgattttc attgagtatc aaaaaaatca gcttcttgat
    32761 aacttcgatt ttcgggtagg gtcaaatcca catcctcctc cacatcatcc actgtcagtt
    32821 caaccgtctg aggtaaattt ttcaaacgat aatgcttttg cctttgccct tcaatactag
    32881 caaaatcaag caaatagcca tgcactcgga tttgaaccaa aaggagatga ttggtcatat
    32941 tttccatgat gaggatatct tctaaaccac ctctggcact aggataatca gataccctgc
    33001 gaatacggat tttttcacac atgagcaagt ttcctcatat caatgatttc atcagcctta
    33061 ttccagacta ggggattatg ggtcgcaatg atgataattc gattttcatc tttcaaatcc
    33121 accaagagat tcataacctc ctctgaattt tcaggatcaa gagctgctgt tggttcatct
    33181 gccaaaatca agggtggatt tttcaaaata gtcttagcaa gggcaactcg ttgggcctct
    33241 cccccagata aagtataaat tttttgttct aaatccaaat accctagatt aactttttct
    33301 aaagccccca cttgcctttc caaacgttct acttttgaga ttttctgacc aacaaaaccc
    33361 aaatccaaat tttctttgat tgattggttt tctaagaggc cgaaattttg aaagagatag
    33421 cccatctggt ctcgaaaata ctcacgagta ggaatggttt ttaaatcttt cccctgatag
    33481 agaacccttc caccatctat cttttctagc tttcccaaga tattcagcag cgtcgtcttt
    33541 ccgcttccac tctttccgat taaggcataa accttgccct tctccagctt gagattcaaa
    33601 ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc cttgaatatc aatcatctta
    33661 ttttcctttc aatactgcca tgctaccagc ttcttctttt ttatcctgcc ttactaaaat
    33721 caagagggcg ttaagcgtaa acaaagctac aactagagcg ctaatcaaac catctcttgt
    33781 caaaatacta gataggacta ggccaagcaa gagaactcct ccttgcgcca gtaaatactt
    33841 gccatgaagc tcatagattg tcataccagc aagacgttta atcataagtt cccgtctgaa
    33901 ctgctcaaaa tagagaagat tcatggaatc aaataacaag atagccgtag acagggtcaa
    33961 aatcgtccca ataaggagag agtaaaactc cacccgtttg tcatttagta ccttggcaaa
    34021 aaatagctgg ctttttacca agtaagaaac cttgtgatac agaccttgct cttttagagc
    34081 tgtgatgctg tctccatatc gatctagttt caaggcacta ttagccgtag ttccccacaa
    34141 catccctgca acaggtcttg ttccagtcgc ttgcggcgtt agaactacaa taatcggatc
    34201 ttttaggtac tggcgtgttg tcttgtaccc atcattatag aggaaacgtt cctgtcctgt
    34261 ttctgtaaaa gctagcctta cctgtgggag gtagtgtttc tgactcgtca cttctacact
    34321 ttcagatgaa aagttttgca ggtaatctgt aaacaatcct tggtagtagg cagactgctc
    34381 tcgcaagctc tcaggcaaga tcagcccaaa ctctccctca gacaagtttt gcatcttgtc
    34441 cataaactct gaagaaacgg taatcttttc ttctatcaga tagcgcggcg agacatagat
    34501 aacattccct aacggtgtgt agtcactgag acgattgcca tctaggtcca cttctgctcc
    34561 atctgagaaa ttgtcaacat tgctcataat ataaaaagag tctgtattgg ctaaccgttc
    34621 ttcagtaaat gtctgccact cacgattatc cttacgcgtt ccttcttcat cggcaaatgc
    34681 actagaccaa ccaaaggata gacggtaacg gtctgaggac tggctccatt tattgctagc
    34741 tctctccatt tcctgcattt cacggtagtg gggtaggaga gctgtcgcac tcgatccgac
    34801 caccaataca gctaagagtt gccccaccat catcaatgtc atcatacgtt tgagagggag
    34861 tttccctttc aatagatcca ccagactatt ttcctgtaaa ccaagtagat agacgacact
    34921 tagtaaggta gaaatccctg ccaaggtcaa tccataaagt agaagagcaa tgatgaccag
    34981 ttgtaccgtt gccataaaca aggcaccttg ataccagaga atccccaatc ccaaaagact
    35041 ggataccagc actgagcaga taagctgtct cacatcttct aacactggtc tgagagcaac
    35101 tccaaacaag ctctcaccag ctattaagcg aatccctgcc tgacgaaggg atttgatccg
    35161 ataaatcagg gtcagactca taaaggtcag cagaaaaata gctaaactca gtagcaccat
    35221 aggggtggcc gccaatagta agactatcga aaatggatct tctccattcg aaacaaagcc
    35281 ttgataacca agctctttca aggtggtctg taagctcact ccatccaaac ttcctgacac
    35341 aatcaagtaa gaccctaata aatcactcgt ttctgcactc tccttggagg aaatggtcag
    35401 accttctgga agctctccct caccataagt ggcataggta aagagtgttt ctccagcttc
    35461 atttggctca acgattcgac gggcgatgag actattatgc tctaccgcca agtgactcaa
    35521 agcctctgtc acctcttcgc gactagctac tggttgattt atcatcattc ctgtcacatc
    35581 aacagaagga tagttaccaa ataaaatctc ttctcgatgg tcaacggaag ttatcaccat
    35641 ataaagcgat accaatacca ttgaaatcaa aataaataaa cgtttcatca tttcctccaa
    35701 aaagttactt ggtcacttag tgagaaggtg accaagtaaa gctaaacaat agggctatac
    35761 cattctaaac attatagtag aatgcaactt tctctcccca agaagtacga atccatgcac
    35821 gagaagtccc tccagcacca gcatatccct tgtcagatga accagttttt ctgctaacaa
    35881 ctgttgaact atggtatttt gaagggtgat agtagtttga gtaagcacca ccgttacctg
    35941 aaccataagt ccaaacacca ccttctgggt attgaacggc tgcagaggca actgatacac
    36001 ctccacctaa tgttgctgca atgctcgcta caagagctaa ctttttaact gtttgtttca
    36061 tattgatact cctctatttt tgattacaag attgttgagt tacttgctcc tctttccatt
    36121 atcaacgttg atactattat attaccaaat gatattctaa aattatttgt ttttctctaa
    36181 attgtcaaaa tagcaccctg aaatgaactt ttatagtcat tatactccat ctttatcaca
    36241 ctatcaagga catcaatgtc cttaaaatct aactatttca tattattttt agcttatatc
    36301 taaaaaaaca gttctaaaga cgaactttag aactgttttg atacgaggac aaggacattt
    36361 ttgtcactga ttcactatgt ttataaatat tttttgacat cctcttgcca ttcctctgtc
    36421 aatttcttta ctagaaatcc atctccaatt agcttcgcaa atgttttaga agactgataa
    36481 aatgattcag ctaaactaaa atctctttct actcttaatg cttgcttcca caaaaacata
    36541 aatacaagag gtttcttttg ataatcttga gttttatcca taatttcttg taaacacgat
    36601 agataatcat taaaacaatc agttactcct accttttcaa gacaacacat tcctgaaata
    36661 agagtatctc taattataaa gaagttttct aatttagtta cctttttctg ttccaaaaga
    36721 aagagcatta gcttttcgat ttgatttata aatttggcaa gatcttttct aatgagcatt
    36781 tgataaaaaa acaaacgaat caacaacata tcatttgttg aataaacttc tttttctatg
    36841 atctgagaca tatgttcctc aagtattaac tctgcatatt caggccttct agttctagaa
    36901 gtatccaaac acgcctgcaa tacttcacat gctaattgtt cttctttagg aagattatca
    36961 aagtatgttt tataaatctc ttccaaacac gcttctttct tatcatactc ctcttcttta
    37021 ccatagattg gttcacgtaa aatctggtat ttcaattcta aataagcaga aggaagagct
    37081 gaaaaatccg gcataaggct ataaactgga actcctagcc ggcgagcaat ataggctaac
    37141 ttgggcaaac tcggttgcga agctccactt tcaattcgcg acagttgacg aactgtcagt
    37201 tcttgctcat ctccacaaaa atctggacga ctaattcctt tttctatccg aatctcttta
    37261 attttttgac caattaacat cagacgcctc ctcttctacc tgcttcgaaa aatactgtga
    37321 aacttaaaaa attgtaacgg ctacatcttt cctactcata agatttcata gcttcttcca
    37381 cttctgccaa agtaacccca aacaactcta ggcgtttgag gagttgcttg ccattagaat
    37441 agccgattcg gagagtctct ccgagatatt ctctacgctt acggctgtct gcccctgcta
    37501 gaaaaccaag gcgaatcaag tcgctacgac taatgtcaaa ctgactctca tgttcaaatt
    37561 gttctgtcac ctgagctaga gccgttttca ggtcttcata gctggcatgc tcaattccca
    37621 gagaacgccc cttggtcttg gacttgggaa cagcttcatc tcgcttgaga aaggcatgct
    37681 gaactgttgg aatggccgtc ataatcatgc gccgaatccg ctccccatta aaatctgggt
    37741 ctgtaaagac aatgactcca tgacgttggt gtagacgctg aattcgctct atatcctgat
    37801 cattgatggc agaacctcgt gtctcatagg tctccacatc gaaataacgc ttgagattga
    37861 ccgtatcata gcgaccttca accacgataa cttgagaaat tttctctttc attacttgct
    37921 gtccaatcca aaaattcgtt ctgcatttgc agtcgttgct accgccagct cttctgtcgt
    37981 cataccacgc aagtcagcga taaagtcgac cacatagcga gtataggctg ttttattttc
    38041 acgaccacgc ttgggtacag gtgctaagta aggcgcatct gtttccacca acatcttgtc
    38101 caaaggtaac tctttagctg cttcttggag gtcagttgcc ttcttgaaag tcaccactcc
    38161 tgagaaggaa atggtcatac caagatccac aaacttctct gcccactcaa gcgtccctga
    38221 aaatgaatgc atgataccac cacgaggacc aacgccctca ctcttgataa tctcataggt
    38281 atcttccagc gcatcacggg tatggacaac aaaaggcaaa tccaagtcct tagatagctg
    38341 aatctgacgg cgaaaaacct gctcctgcac ctctttgggc gctgtcatcc aatggtagtc
    38401 taagccaatt tcacctaaag ccacaacctt ggaatgtttt aacttatcca acaagtaagc
    38461 ctcaacttcc tctgtataag taccagcttc tgtaggatgc caaccaatag tcgcatagag
    38521 ctgctcatac tcatctacca actccaaggc acgctcaatc gtcggtttat caaaaccaac
    38581 aatattcatc tgtatcacac ccatctcagc agccaaggca atttcttctg cctcacgacc
    38641 tgcaaattct tctacattca agtgtgtatg tgtatcaaaa atcatctctt ctaacctcgt
    38701 tttctatctt ctattatacc aaaaaagagg aggggcacct aatttttcgg tttcccctcc
    38761 tctcttcaat agagagctat tctgctatct tttctatccg atattgccca tctcctattc
    38821 cacagttaga gacagaagag attggctaca ttgatagaat attcctattc agctaaagta
    38881 tgtgattatc ttgggttctc acttttctca cccatcacta ggattgatga cttctcaaaa
    38941 tcccccttat aatctaactt taagtagaga atagaatttt ctagctgttc tattttctac
    39001 gtctagtctt tcttcctagc aaagcaaaac cacttgttgc caccactaga ccaagactag
    39061 caagtgctgc acttgatgct gaacctgtgt taggtaattg tttgccagca ggtgactggt
    39121 aggtaacatc ttgcattgtt cctgcagttg cttgcggtgc acttgttgtc ttaggagcag
    39181 cattaggagc cactggtctc ttaggaactg taaccatggc aatggcttgc actccaatcg
    39241 tttctgcttc cttcacatct tccatagttt tcgcattttc aatctctttg agagctgctt
    39301 gtttttctgc ttccactctt gctaaaagtt ctgctttttc tttatcagaa agcggtgcgc
    39361 ctttgatttc atcctgctta tccttggctg ctttttcaat ggcattttta gctgattctt
    39421 tttcagtagc taattgctta gaagcttgtg attgagctga gttttgtgaa cctgtgtgag
    39481 ctgatccacc cgcctggcta ccaccgcctt cattcgcatt agcatctgag cttccagtat
    39541 tgcctccctt atctccacct ggtatagttt ctagcttata ctctagtgta gcttcttgag
    39601 ttacagattc acctttcgca gattgttgaa ctgtatcttt tcctagaatc gtcactactg
    39661 aaccatctgg gaatgtgatt gttgctgtac catctccagc tacattgatt gtcgctccgt
    39721 ctaatgctga accatttgct tgtaaaatag caaccttaac tttttcttca tctgttaaat
    39781 gagttatatc ttttacatct actctttgag caggtgcttt aacagttgat ttttcagcag
    39841 tcggtttagt gctatcttgt gcttttggat cttgtgctac caattgattt cctggaattg
    39901 taatagctga accatcttta aagacgattg ttgctgtacc atctccacct acttcaactt
    39961 tatagtaaaa taaaataata acaggacaaa tcgatcagga cagtcaaatc gatttctaac
    40021 aatgttttag aaacagaggt gtactattct agtttcaatc tactataaca tcgcttccga
    40081 atccatttgc atctactgaa cttttttaca aaaataaaaa tcagtagact cgagttccta
    40141 ctgatttttg atagaattcg tttggattat gcagccaaaa ctttgcgtcc tttacgacga
    40201 cgagctgcca atacgcgacg accattttta gttgacatac ggttacggaa tccgtgttta
    40261 cgcgcacgac gaagtttact tggttgataa gtacgtttca cgatgaatac ctcctcatag
    40321 attttgtatt cgtttagccg gctataaagt gatcagttac taaacatact ttactattct
    40381 atctgattct ttcacttttg tcaatagctc taggcaaatg tttccagctt tttcgaatgc
    40441 aagccctatt gaaagttcta taatgaagtt agccacctta ccttagtcaa gaattagatg
    40501 tttcactatg tttgagtaag ttgatgattt catttgataa caggtttgaa actgttaggc
    40561 taggtggcca aggctaatca tagccttggt ttagctgaaa aaacaggttc aagggttcct
    40621 gttgtcaaat gaaatgtgat ttaaggtata agaaaacacc tctgtgctat acttgttgtt
    40681 caccacaaac acaaggaaag gcacagagat gcaagaacat tataccccaa aagggaaaca
    40741 tttgacaata gataaccgtc gcttgattga gcggtggaag aatgaaaata agtccaatcg
    40801 tgaaattgca ggcttgttag gaaaggcgcc tcaaacgatt cata
//
LOCUS       DAVLAQ010000013        40237 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000013 DAVLAQ010000000
VERSION     DAVLAQ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.013"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            5..75
                     /locus_tag="VXB71_000665"
     tRNA            5..75
                     /locus_tag="VXB71_000665"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VXB71_000666"
     tRNA            110..183
                     /locus_tag="VXB71_000666"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VXB71_000667"
     tRNA            266..355
                     /locus_tag="VXB71_000667"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VXB71_000668"
     tRNA            366..439
                     /locus_tag="VXB71_000668"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VXB71_000669"
     tRNA            443..515
                     /locus_tag="VXB71_000669"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VXB71_000670"
     tRNA            528..608
                     /locus_tag="VXB71_000670"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VXB71_000671"
     tRNA            613..683
                     /locus_tag="VXB71_000671"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VXB71_000672"
     tRNA            698..770
                     /locus_tag="VXB71_000672"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="VXB71_000673"
     tRNA            784..855
                     /locus_tag="VXB71_000673"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="VXB71_000674"
     tRNA            865..948
                     /locus_tag="VXB71_000674"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="VXB71_000675"
     CDS             1055..2332
                     /locus_tag="VXB71_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0450821.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /locus_tag="VXB71_000676"
     CDS             2408..3892
                     /locus_tag="VXB71_000676"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0450822.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="VXB71_000677"
     CDS             3953..5233
                     /locus_tag="VXB71_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0450823.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="VXB71_000678"
     CDS             5237..5857
                     /locus_tag="VXB71_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0450824.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7135
                     /locus_tag="VXB71_000679"
     CDS             6023..7135
                     /locus_tag="VXB71_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0450825.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7458..7883
                     /locus_tag="VXB71_000680"
     CDS             7458..7883
                     /locus_tag="VXB71_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0450826.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7894..8253
                     /locus_tag="VXB71_000681"
     CDS             7894..8253
                     /locus_tag="VXB71_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV0450827.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8360..9004
                     /gene="pcp"
                     /locus_tag="VXB71_000682"
     CDS             8360..9004
                     /gene="pcp"
                     /locus_tag="VXB71_000682"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0450828.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9032..9889)
                     /locus_tag="VXB71_000683"
     CDS             complement(9032..9889)
                     /locus_tag="VXB71_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0450829.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10019..11161
                     /gene="tgt"
                     /locus_tag="VXB71_000684"
     CDS             10019..11161
                     /gene="tgt"
                     /locus_tag="VXB71_000684"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0450830.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="VXB71_000685"
     CDS             11259..13076
                     /locus_tag="VXB71_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0450831.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="VXB71_000686"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="VXB71_000686"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0450832.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="VXB71_000687"
     CDS             14543..15601
                     /locus_tag="VXB71_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0450833.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="VXB71_000688"
     CDS             15752..16117
                     /locus_tag="VXB71_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0450834.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16193..17134
                     /locus_tag="VXB71_000689"
     CDS             16193..17134
                     /locus_tag="VXB71_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0450835.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17082..18098
                     /locus_tag="VXB71_000690"
     CDS             17082..18098
                     /locus_tag="VXB71_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0450836.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18100..18426
                     /locus_tag="VXB71_000691"
     CDS             18100..18426
                     /locus_tag="VXB71_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEV0450837.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18419..18823
                     /locus_tag="VXB71_000692"
     CDS             18419..18823
                     /locus_tag="VXB71_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0450838.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18828..19088
                     /locus_tag="VXB71_000693"
     CDS             18828..19088
                     /locus_tag="VXB71_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450839.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19051..19512
                     /locus_tag="VXB71_000694"
     CDS             19051..19512
                     /locus_tag="VXB71_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0450840.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19490..19936
                     /locus_tag="VXB71_000695"
     CDS             19490..19936
                     /locus_tag="VXB71_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0450841.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            20039..20626
                     /locus_tag="VXB71_000696"
     CDS             20039..20626
                     /locus_tag="VXB71_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0450842.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20687..21640
                     /locus_tag="VXB71_000697"
     CDS             20687..21640
                     /locus_tag="VXB71_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0450843.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21691..22881
                     /locus_tag="VXB71_000698"
     CDS             21691..22881
                     /locus_tag="VXB71_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0450844.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYFAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23030..23401
                     /gene="rnpA"
                     /locus_tag="VXB71_000699"
     CDS             23030..23401
                     /gene="rnpA"
                     /locus_tag="VXB71_000699"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0450845.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23376..24200
                     /locus_tag="VXB71_000700"
     CDS             23376..24200
                     /locus_tag="VXB71_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0450846.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24219..25205
                     /locus_tag="VXB71_000701"
     CDS             24219..25205
                     /locus_tag="VXB71_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0450847.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25256..25879
                     /locus_tag="VXB71_000702"
     CDS             25256..25879
                     /locus_tag="VXB71_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0450848.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26010..27467
                     /locus_tag="VXB71_000703"
     CDS             26010..27467
                     /locus_tag="VXB71_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0450849.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27490..27771
                     /locus_tag="VXB71_000704"
     CDS             27490..27771
                     /locus_tag="VXB71_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0450850.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27848..28333
                     /locus_tag="VXB71_000705"
     CDS             27848..28333
                     /locus_tag="VXB71_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0450851.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGLYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28350..29015
                     /locus_tag="VXB71_000706"
     CDS             28350..29015
                     /locus_tag="VXB71_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0450852.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29019..29882
                     /locus_tag="VXB71_000707"
     CDS             29019..29882
                     /locus_tag="VXB71_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0450853.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29884..30588
                     /locus_tag="VXB71_000708"
     CDS             29884..30588
                     /locus_tag="VXB71_000708"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0450854.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30767..32440
                     /locus_tag="VXB71_000709"
     CDS             30767..32440
                     /locus_tag="VXB71_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0450855.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32552..33643
                     /gene="ulaG"
                     /locus_tag="VXB71_000710"
     CDS             32552..33643
                     /gene="ulaG"
                     /locus_tag="VXB71_000710"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0450856.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33757..35733
                     /gene="tkt"
                     /locus_tag="VXB71_000711"
     CDS             33757..35733
                     /gene="tkt"
                     /locus_tag="VXB71_000711"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0450857.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35850..36149
                     /gene="yajC"
                     /locus_tag="VXB71_000712"
     CDS             35850..36149
                     /gene="yajC"
                     /locus_tag="VXB71_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0450858.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36196..36624
                     /locus_tag="VXB71_000713"
     CDS             36196..36624
                     /locus_tag="VXB71_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0450859.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36626..37036
                     /locus_tag="VXB71_000714"
     CDS             36626..37036
                     /locus_tag="VXB71_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450860.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37336..39987
                     /gene="adhE"
                     /locus_tag="VXB71_000715"
                     /gene_synonym="adhC"
     CDS             37336..39987
                     /gene="adhE"
                     /locus_tag="VXB71_000715"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0450861.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12207 a         7212 c         9065 g        11753 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttaacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac ttgcagtagc
     6781 aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
     6841 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
     6901 aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata agattgcgga
     6961 atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
     7021 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
     7081 tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg gataaacccg
     7141 acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag cgattctcgt
     7201 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgaa
     7261 acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
     7321 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
     7381 ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga taaatcaata
     7441 aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg
     7501 agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca cggtatcaga
     7561 ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag gagcgtttga
     7621 aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa ggtttggtgg
     7681 agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg aagtatgcca
     7741 aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa gagatagaaa
     7801 gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa ttggttttgg
     7861 gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac aacgatcgtt
     7921 gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc agatgcgact
     7981 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     8041 aaaaatcaag gaatttataa ggctctgcta ggagtctttc tcttgtatgt catttatttc
     8101 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8161 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8221 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8281 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     8341 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct ttggagggga
     8401 aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8461 ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8521 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8581 tttgacacct gaacgagtga ccattaatca agacgatgca tgcatttctg ataacgaaga
     8641 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8701 gccgattaaa gcgatggttc aagctataaa aaaagagggc ttaccggcct ctgtttccaa
     8761 tacggcaggg acttttgtct gcagccattt gatgtatcag gctctctatt tggtagaaaa
     8821 gaaatctcca tatgttaagg caggttttat gcatattcct tatatgatgg aacaggtggt
     8881 gaacagaccg actactccag ctatgagttt agtggatatt cggcgaggga tagaagcagc
     8941 aatcggcgct ataatagaac atggagatca ggaactcaag ttggtaggcg gagaaactca
     9001 ttgatagaaa aaagcttgag gagaaaaacc ttcaagcttt tggacgtttt cgggccaata
     9061 ctgctcggta aaacataatt ttagtgcatt ggatataagg taggagtgaa aaactagcaa
     9121 tgccaaaggt aatccaattg aggaagtacc aaggaagaag ctgtaaatct aggacaaagt
     9181 gctggaactt gtagcccttc ataaaggaac ggctagtttt taggattcgt cttggtggga
     9241 cctgtcctag gtctagacta taacagagaa gaaattccac ctgtgaatag gcataatact
     9301 gtggaatata gaggatattt cctacaatga tcaagatgag acttgcaaga aagtagagtc
     9361 caaagaccat gaggaaacgc tcggtttcaa ctgatgagag atctagattt ggaaactcag
     9421 gatgtagggt gacgaatttt ttggctaaaa agctactata aaagaggagg taaatcccaa
     9481 gtaaattagg gatactccat aaaaagagat agaaacgttt gagaagtagg gtcaaaaagg
     9541 tttgagaaaa gcgctcctca tcaaagagag ctaggctgtt ttttacagat ggctccgttt
     9601 tagaatcttt catgagtgtc agtgttgcat agacggaact ggtcaaaaga atagtcccga
     9661 taaaggagac tagtagagga aagaggtagg tttgaagtat ttggccaagt atgctgaaaa
     9721 atggctgttc taaaacagtc ccgtggatcc gagataaggg attaagaaaa ccagataaga
     9781 tgaccagcat actgggaagg atatagagga gaaagagacg gggggtgtca gcctgaaaat
     9841 gttttgactc ctgacgaatt gtttttaaat caatttttgg atagttcatt ctcttattat
     9901 accatagttc ttatacatag ttcgtgacag ttcctacttt ttttgataaa atcatacagt
     9961 gtgtccttgg gcacactgta tgaactggga ctgtctttcc cagcttcgga ggtaaaaaat
    10021 gtcagattca ccaatcaaat atcgtttgat taagaaagaa aaacacacag gagctcgtct
    10081 gggagaaatc atcactcccc acggtacctt tccgacacct atgtttatgc cagttgggac
    10141 acaagccact gtcaaaactc agtcacctga agaattgaag gagatgggtt cgggaattat
    10201 cctatcaaac acctatcatc tctggcttcg ccctggagat gaactcattg cacgcgctgg
    10261 tggtctccac aagttcatga attgggacca gcctatcttg acagatagtg gtggttttca
    10321 ggtttattct ttagcagata gccgtaatat cacagaagaa ggagtaacct ttaaaaatca
    10381 tctaaatggt tctaagatgt tcctatcccc agaaaaagcc atctctattc agaataatct
    10441 gggttcagac atcatgatgt cctttgatga atgtcctcag ttttatcaac cttatgacta
    10501 cgttaagaaa tcgatcgagc gtaccagccg ttgggctgag cgtggtttga aggctcaccg
    10561 tcgtccacat gaccaaggtt tgtttggaat tgtgcaaggt gcaggatttg aagaccttcg
    10621 ccgccaatca gctcatgatc ttgtcagcat ggatttctca ggctactcta tcggtggttt
    10681 ggcagtggga gaaacccatg aagagatgaa tgcggtcttg gactttacaa ctcaactgct
    10741 acctgaaaat aaacctcgtt atctgatggg tgtgggagcg ccagatagct tgatcgatgg
    10801 ggtcattcgt ggggtggata tgtttgactg tgtcttaccg actcgaattg ctcgtaacgg
    10861 gacttgtatg accagtcaag gacgtttggt tgtgaaaaat gcccagtttg ctgaggactt
    10921 tacgccactg gatcctgagt gtgactgcta cacatgtaat aactatacac gcgcttacct
    10981 tcgtcacctg ctcaaggctg atgaaacctt tggtatccgc ttgactagct accacaatct
    11041 ttacttcttg cttaacctga tgaagcaagt gcgacaagcc atcatggatg acaatctctt
    11101 ggaattccgt gagtattttg tggaaaaata tggctataat aagtcaggac gtaatttcta
    11161 aaatggaatt gatataaaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgctgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 tgggaagtat gttagcaact attgtaggtg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattctat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgtagcaggt acaggaatct tgaccatcat tgtctgcacg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagacaagcc ggttaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctata atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctat ctagatggcg taaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggcg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctga aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgttggt attcctgcaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccaga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctatg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggctg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16141 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16201 agaaattgca caagaaatca ttcgttcagc tcggaaaaaa gggacgcagg atatttattt
    16261 tgtccctaag ttagacgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16321 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16381 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16441 gaagatggcg tctctacgtt tatctactgt aggcgattat cgggggcatg agagtttggt
    16501 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16561 attaggcaag cagtacaggc aacggggact ctatcttttt gctggtccgg ttgggagtgg
    16621 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16681 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16741 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagatctctt
    16801 gattatcgga gaaattcgtg acagcgagac ggcgcgtgca gtggtcagag ctagtttgac
    16861 aggtgcgaca gtcttttcaa ccattcacgc caagagtatc cgaggtgttt atgagcgtct
    16921 gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt ctgcaaggag tctgctacca
    16981 gagattaatc gggggaggag gaatcgttga ctttgcaagc agagattatc aagaacacca
    17041 agcagccaag tggaatgagc aaattgacca gcttcttaaa gatggacata tcacaagtct
    17101 tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accctattta
    17161 acaatctctt ttctagcggt tttcatctgg tggagactat ctccttttta gataggagtg
    17221 ctttgttgga caagcagtgt gtgatccaga tgcgtgcggg cttgtctcag gggaaatcat
    17281 tctcagaaat gatggaaagt ttgggatgtt caagtaccat tgtcactcag ttatctctag
    17341 ctgaagttca tggcaatctt cacctgagtt tgggaaagat agaagaatat ctagacaatc
    17401 tggccaaggt caagaaaaag ttaattgaag tagcgaccta tcctttgatt ttgctgggtt
    17461 ttcttctctt aattatgctg gggctacgga attacctgct cccacaactg gatagtagca
    17521 atattgccac ccgaattatc ggtaatctgc cacaaatttt tctaggcatg gtagggcttg
    17581 tttccgtgct tgccctttta gcactaactt tttataaaag aagttctaag atgagtgtct
    17641 tttctatctt agcacgcctt ccctttattg gaatctttgt gcagacctac ttgacagcct
    17701 attatgcacg tgaatggggg aatatgattt cacagggaat ggagctgacg cagatttttc
    17761 aaatgatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ctggctcaaa
    17821 ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaggaagg
    17881 aattgagtct catcatagag tatggggaag ttaagtccaa gctgggtagt gagttggaaa
    17941 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatttgg
    18001 tgcagccact ggtttttatc tttgtggcac tgattatcgt tttactttat gcggcaatgc
    18061 tcatgcccat gtatcaaaat atggaggtaa atttttaaaa tgaaaaaaat gatgacattc
    18121 ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga tgttagtagt cttgctgatt
    18181 atcagcgtgc ttttcttgct ctttgtacct aatctgacca agcaaaaaga agcagtcaat
    18241 gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc aggcagaact ttatagcttg
    18301 gataaaaatg aagatgctac tctgagcaag ttacaaggag atgggcgcat cacggaagaa
    18361 caggttaaag cttataatga atactatact aaaaatggag gggcaaatcg taaagtcaat
    18421 gattaaggcc tttaccatgc tggaaagtct cttggttttg ggacttgtga gtatccttgc
    18481 cttgggctta tccagctctg tccagtccac ttttgcagca gtagaggagc agattttctt
    18541 tatggagttt gaagaactct atcgggaaac ccaaaaacgc agtgtagcca gtcagcaaaa
    18601 gactagtcta aatttagatg ggcagacgct tagcaatggc agtcaaaagt tgacagttcc
    18661 taaaggaatt caggcaccat caggccaaag tattacattt gaccgagctg ggggcaattc
    18721 gtccctggct aaggttgaat ttcagaccag taaaggagcg attcgctatc aattatatct
    18781 aggaaatgga aaaattaaac gcattaagga aacaaaaaat tagggcagtg attttactgg
    18841 aagcagtagt cgctctagct atctttgcca gcattgcgac cctccttttg ggacaaattc
    18901 aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga agaagtcttg agggtagcta
    18961 agatggccct gcagacgggg caaaatcagg taagcatcaa cggagttgag attcaggtat
    19021 tttctagtga aaaaggattg gaggtctacc atggttcaga acagttgttg gcaatcaaag
    19081 agccataagg tcaaggcttt taccttgtta gaatccctgc ttgccctcat tgtcatcagt
    19141 gggggattac tcctttttca aactatgagt cagctcctca tttcagaagt tcgctaccag
    19201 caacaaagcg agcaaaagga gtggctcttg tttgtggacc aacttgaggc agaattagac
    19261 cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca tgaagcaaga tggcaaggac
    19321 atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa ccgatgctag tggacggggg
    19381 tatcagccta tggtttatgg cctcaaatca gctcagatta cagaggacaa tcaactggtt
    19441 cattttcgtt tccagtttca aaaaggctta gaaagggagt tcatctatcg tgtggaaaaa
    19501 gaagaaagtt aaggcaggtg ttctcctcta cgcagtcacc atagcagcca tctttagtct
    19561 tttgttgcaa ttttatttga accgacaaat cgcccactat caagactatg ctttaaataa
    19621 agaaaaattg gttgcttttg ccatggctaa acgaaccaag gataaagccg agcaagaaag
    19681 tggggaacag gtttttaatc taggtcaggt aagctatcaa aacaagaaaa caagcttggt
    19741 gacgactgtt cgtacgtcta agagccaata tgagtttctg tttccttcag tcaaaatcaa
    19801 agaagagaaa agagataaaa aggaagaggt agcgaccgat tcaagcgaaa aagcggagaa
    19861 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    19921 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19981 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ctaaagatat
    20041 gaaacatgat tttaaccaca aagcagaaac tttcgactcc cctaaaaata tcttcctcgc
    20101 aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca aagtaatttt
    20161 agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg ctaagtcagt
    20221 tactcttgta gacatttctg agaaaatgtt ggagcaagct cgtttgaaag tggagcagca
    20281 agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct tggagaaaga
    20341 gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg atgcggctct
    20401 ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg attttaccaa
    20461 gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc taattgagca
    20521 tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacctgt ttcaaggaaa
    20581 tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag ggagtgattt
    20641 ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg attttgaaaa
    20701 aattgaacaa gcttatacct atttactaga gaatgtccaa gttatccaaa gtgatttggc
    20761 gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg gtgaaactga
    20821 gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac gcaaagaaga
    20881 atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac ccttgcaggc
    20941 caatcaccag tttacaccag atgccattgc tttgcttttg gtgtttattg tggaagagtt
    21001 gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa ttctaggcgc
    21061 tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaaa tggatgattt
    21121 gctgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg gctttgtcca
    21181 aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca gtgacttgcc
    21241 tgttggctat tatcctgatg atgccgttgc gtcgcgccat caagttgctt ctagccaaga
    21301 acatacttac gcccatcact tgctcatgga acaagggctt aagtacctca agtcagacgg
    21361 atacgctatt tttctagctc cgagtaattt gttgaccagt cctcaaagtg atttgttaaa
    21421 agaatggctg aaagaagagg cgagtctggt tgctatgatt agtctgcctg aaaatctctt
    21481 tgctaatgcc aaacaatcta agactatttt tatcttacag aagaaaaatg aaatagcagt
    21541 agagcctttt gtttatccac ttgctagctt gcaagatgca agtgttttaa tgaaatttaa
    21601 agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt gttataatag
    21661 ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat caatgcagga
    21721 agttcaagtt tgaaatggca attatactta atgccagaag aaaaagtgtt agccaaaggt
    21781 ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga cggccgttct
    21841 gaacaacaaa ttttggatat tgaaaatcat acacaagccg ttaaaatttt attggatgac
    21901 ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg acatcgtgtt
    21961 gttgctggtg gagaatattt caaagaatca acagttgttg agggagatgt tttagaaaaa
    22021 gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc aggtgttcgt
    22081 gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac ttccttccac
    22141 acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta cacagaaaac
    22201 aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg agaagctgca
    22261 aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat tggtaacgga
    22321 ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg gttcactcct
    22381 cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat cattccttat
    22441 ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt tcttaaccgt
    22501 gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat agaagcagct
    22561 gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga ccgtatccaa
    22621 aaacatatcg gtcagtactt tgcagtgcta aatggagcag atgccattgt tttcacagca
    22681 ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat ttcgtggttt
    22741 ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat ctcaacagag
    22801 gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat tgcccgtgac
    22861 gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg agttgggaaa
    22921 gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat gattggcttt
    22981 tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt tgaagaaaaa
    23041 ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga caagttttgc
    23101 taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc gagtaggtct
    23161 atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc gacggattcg
    23221 gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg ttgtcattgc
    23281 tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac tccatgtatt
    23341 aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta aagttgacta
    23401 gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg gtaactagcg
    23461 atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt gcgaaaatca
    23521 ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt acggtcttga
    23581 ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg aaaatgcagg
    23641 aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat atggaaagca
    23701 gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc agacagtcag
    23761 attctctttg gccgattttg attcagatgc cggttatttt ggccttgttc caagccctat
    23821 caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt agtgtggata
    23881 caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact tggttgtcca
    23941 acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg attccagtct
    24001 tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg acagtgtcta
    24061 atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt atcgcagagc
    24121 gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa gccaagaaaa
    24181 aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt acaggttcaa
    24241 ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga atgaaggctc
    24301 atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt aaaaaaccag
    24361 cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat caacaggtag
    24421 taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg gttagtgaag
    24481 aaaccgttga ccttggtcat gtggttgatg ctattaaaaa aatagaggaa gaaggtcaag
    24541 gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc agcactatct
    24601 tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa gcgatgaggg
    24661 aagaagcagg cgctgatgac cttgaaactg agcaagatca aactgaaaat caagacttga
    24721 aagagatggg cttgaaggtc gagcaaagtt atgatattgc ccaggtggct acggatgtga
    24781 ctgcctatgt tcaagcgatt gtggatgaca tggatgttga agctacactt tcaaatgatt
    24841 ataaccgtcg tagcatcaat ctacaaattg acaccaacga accaggtcgt attatcggct
    24901 accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt tacaaccgct
    24961 attccaaaac cttctacgtt acaatcaatg tcaatgatta tgtcgaacac cgtgcagaag
    25021 tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga cgtagtcatc
    25081 aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt tcacgtatgg
    25141 atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt gtagatacag
    25201 aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta aactgatgtt
    25261 gaataagata agagactatt tagactttgc tggtttgcag taccgtaatc ctgataaagc
    25321 gggagcagag cgagagaaga tgctggcatt ccgccacaaa ggacaagagg cccgaaaggc
    25381 ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac tccaacagac
    25441 tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt atctacagag
    25501 agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat ctactgactt
    25561 tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa cactgggcaa
    25621 gcaggccaaa gttttagaca ttccaaccgt taaagggatt tattatctaa cctactctaa
    25681 tggtcaaagt caacggtggg aggcgaatga agaaaagcgt cgtactttac gcgagaaggt
    25741 gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga cagaaaattc
    25801 gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc ttccctatta
    25861 tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag tccaagagtg
    25921 aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat ataataaact
    25981 tacaaaaaca attcaaaagg agaacaatta tggaagtcgt ttcaagtgtt ctaaattggt
    26041 tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg ttgataggat
    26101 atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa gcaacagtag
    26161 ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt ccaatcttag
    26221 cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac tttggacttg
    26281 ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact gcaactacag
    26341 ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag attacgaagg
    26401 taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca gtatctctta
    26461 tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg attggtatca
    26521 tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact caacgcttga
    26581 ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg tttgtagata
    26641 aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa ttacctaagt
    26701 tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc gtattcttcg
    26761 gggccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc atcacttcag
    26821 gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa acagccttta
    26881 ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta tctgagttga
    26941 caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca gcggttgacg
    27001 ttgcagcttc ttatggattt ggttctccaa atgctgtctt gtcaggattt acctttggtt
    27061 tgattggtca attgattaca attgtcttgc tcatcgtctt taaaaatccg attcttatta
    27121 ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac gctgataaac
    27181 gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt caagttgctc
    27241 taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac catggaaata
    27301 tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt ggtattgttg
    27361 gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt gccaaagcaa
    27421 aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat ctagaaaagg
    27481 agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc atcaatggtt
    27541 atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt tacagtcaat
    27601 tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt aatcgcttct
    27661 cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg acttgataac
    27721 ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta aaaggttgga
    27781 gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt aaataaagga
    27841 ggcagatatg aatttaaaac aagctttaat tgacaatgac tcgatccgac taggtttaga
    27901 ggctaacaat tggaaagaag cagtcaaggt agcagtagat cccttaattg aaagtggggc
    27961 aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg ggctttacta
    28021 tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg tgcaaagtga
    28081 tgccttttca ttgattacct tacaaaatcc tgttgtattt tcagatggga aagaggtatc
    28141 tgttttgttg gcactagcag caacaagctc aaaaattcac acaagtgtag ccattccaca
    28201 aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt gccagactaa
    28261 agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg aaggattgga
    28321 tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat ttacaagttg
    28381 cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt ggtcaggaag
    28441 tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa ctggctgaag
    28501 tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt gctgatgctg
    28561 gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact tgtatctgtt
    28621 gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa cgaggagaac
    28681 gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct cagctttggc
    28741 tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt cttgctggtg
    28801 aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg ggcttccgtg
    28861 tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt gttgatgtct
    28921 ttacctttat cgcaggtcgt ggaattacag aggctgcgga tccagcagga gcagcgcgtg
    28981 ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca attggaattt
    29041 atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt gccaaggagt
    29101 taggctttga ttttgtcgag atgtctattg acgaacgtga cgagcgttta gcaagacttg
    29161 actggagtaa ggaagaacgc ttggaagttg tcaaagcaat ctatgaaact ggtgttcgta
    29221 ttccttctat ctgtttttca ggccatcgtc gctacccatt gggttcaaaa gatccagttc
    29281 tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa gacttgggag
    29341 ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca ccccagacac
    29401 gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa gctcaggtgg
    29461 tacttgctat tgaaattatg gatgatcctt tcatcaatag catcgaaaaa tatttggcta
    29521 tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt aatgtgtctg
    29581 catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc gcagctctcc
    29641 atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga gatgtacctt
    29701 tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa accaattata
    29761 atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa gaaacacgcg
    29821 cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca ggtttgatgt
    29881 aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa tcaatcattg
    29941 ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa tcgcgaactc
    30001 ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc tgaaaacatg
    30061 gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc ttccgacctc
    30121 ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt tcacacccat
    30181 tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta cggaacaacc
    30241 catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa ggacgaagta
    30301 gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga acatcgcgga
    30361 cttaacccgg ttgaagtacc aggaattgtt gtacgcaatc acggtccatt cacctggggc
    30421 aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc aaagatgaat
    30481 cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat actagaaaaa
    30541 cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga acgatgaagg
    30601 aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga gagtaaagtt
    30661 ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata tatggtaaaa
    30721 taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg tactggataa
    30781 ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa cgattatggc
    30841 gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg acaaaatcaa
    30901 tgctgctctg gttgacgagg cgcttcacat cattagtatt ccacgaattg gtattcactt
    30961 aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt cgtacgatta
    31021 tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta tttctaaaga
    31081 acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata ctgttctcaa
    31141 tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga tcttgcaagt
    31201 gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc agtatcttca
    31261 atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta ttttagaaga
    31321 taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga accaattttt
    31381 taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc atcatgaaat
    31441 aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg ttgaacagta
    31501 tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa gaatagagta
    31561 tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt ctttgtcagg
    31621 acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaggatt tggatattca
    31681 tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta tctggtattt
    31741 tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa atttgatgat
    31801 ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa atcctctaac
    31861 aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat ctgcggaaat
    31921 tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt tgacgattca
    31981 tattggagga tttttaaagt atacaccatc gtctcaaaaa aatatgaaaa aagtttatct
    32041 cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca aactttattt
    32101 tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg tggaagatat
    32161 tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat ttccgatttt
    32221 aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact atcttaaaca
    32281 caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc ttatttcgtc
    32341 ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa cacttataaa
    32401 taaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc aatgatgaac
    32461 acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata ctaatctcaa
    32521 agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa ttacaagaga
    32581 gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag aaatcgaaga
    32641 agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg gtacttggat
    32701 taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg gaaaatcaac
    32761 caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag gtgttcgtaa
    32821 gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta tcaacgaact
    32881 agactattac ttagtttcac acttccacag tgatcatatc gacccataca cagctgcagc
    32941 aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc actgtggacg
    33001 aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac caggtgacac
    33061 tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta cttgcttggt
    33121 aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct tggctgttac
    33181 agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag gtggaaccat
    33241 ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta aagactttaa
    33301 aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag acaaaatgac
    33361 atctatcgat cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta tcccagttca
    33421 ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac tttggaaaat
    33481 gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg gcggtaagta
    33541 cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt ttgatgattg
    33601 ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa atattctttg
    33661 gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa atagaatgtg
    33721 tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc tgttaatgca
    33781 attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc aggtgtggtt
    33841 atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat caatccagct
    33901 caaccaaatt ggattaaccg cgaccgcttt attctttcag caggtcatgg ttcaatgctc
    33961 ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga gattaagagt
    34021 ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac ggcagggatt
    34081 gatgctacga caggtcctct agggcaaggg atttcaactg ctactggttt tgcccaagca
    34141 gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga ccactatact
    34201 tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc agcttcatac
    34261 gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga tatcaacttg
    34321 gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa tgcctacggt
    34381 tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc tgctatcgaa
    34441 acagcaaaag cttcaggcaa gccatcttta attgaagtga agacggttat tggatatggt
    34501 tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc agatgaaacc
    34561 gcatcaactc gccaagccct cggttgggac tacgaaccat ttgaaattcc agaacaagta
    34621 tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca agcttggact
    34681 aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt agaagccatc
    34741 atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt agaaaatggt
    34801 ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc agctaaatta
    34861 ccaaccttcc taggtggatc agctgacctt gctcactcaa acatgactta tatcaagacg
    34921 gatggacttc aagacgatac caatcgcttg aatcgtaaca ttcagtttgg tgttcgtgaa
    34981 tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg tgtatacggt
    35041 ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc agccttacaa
    35101 ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga agatggtccg
    35161 actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct aaatgttttc
    35221 cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac aagtgagaaa
    35281 acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg aacagacttc
    35341 gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt tgataccatc
    35401 ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga attggctagt
    35461 caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga taaacaagat
    35521 gcagcttaca aggaagagat tcttccaaat gcagtccgcc gtcgtgttgc agtcgaaatg
    35581 ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct aggtattgat
    35641 accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt tactgtagaa
    35701 aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg taagctctgg
    35761 tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt tgatatagta
    35821 gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt ttaatcatgc
    35881 ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa caagctcaaa
    35941 agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca atcggtggac
    36001 tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt gacgtagatg
    36061 gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg aaagaaacag
    36121 cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt ttttctataa
    36181 aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat ttgccgtagc
    36241 cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca aagtcgagca
    36301 acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat ttttcaagag
    36361 tatgagattc cttatgacaa gaacaagaca tcgcttcaga ttagtaagga agattttgaa
    36421 gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttatg tcagatgtgt
    36481 ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc agacccttgg
    36541 tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca agcttggtta
    36601 gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg aaaagtatcg
    36661 tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg ttttttgtgc
    36721 tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg ataatggaac
    36781 gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggccaaggta ccattacctt
    36841 ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg gaaaaggtac
    36901 ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc aggctgaagg
    36961 aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta aacaaggcgt
    37021 ttttcaacaa aaataaagcc tccttatcaa aggaggtatt attagaatca caaggtaagc
    37081 gcttacctgt aaatcccttt ctttccaaat ccctcttcca agcaagtttg tgaaataaaa
    37141 aatatttgaa ataaatttca caaacttcaa agataaaact tgataagaaa agaaaatgag
    37201 aaaagtttca caagagttta aaaattcttt gtgaaatgtt tatgaaactg tttacaaagt
    37261 tgaaataatg cgttataata aacttgtgaa aaaattaaca aaggatatcg ttccttgaaa
    37321 gctatggagg aaaatatggc tgataaaaaa actgtgacac cagaggaaaa gaaactcgtt
    37381 gctgaaaaac acgtagatga gttggttcaa aaagctctag ttgcccttga agaaatgcgt
    37441 aaattggatc aagaacaagt tgactacatc gttgccaaag catcagtagc agctttggat
    37501 gcccacggag aattggcttt acatgccttt gaagaaacag gacgtggtgt atttgaagac
    37561 aaagcaacta agaacttgtt tgcttgtgaa cacgtagtaa acaatatgcg ccacactaag
    37621 acagttggcg ttatcgaaga agacgatgta acaggattga ctcttattgc tgaaccagtt
    37681 ggtgttgttt gtggtattac tccaacaaca aacccaacat caacagcaat cttcaaatca
    37741 ttgatttcat tgaagacacg taacccaatc gtctttgcct tccatccatc agcacaagaa
    37801 tcatctgctc atgcagctcg tatcgtccgc gatgcagcta tcgcagctgg tgctcctgaa
    37861 aactgtgtgc aatggattac tcaaccatct atggaagcaa caagtgccct tatgaaccac
    37921 gaaggtgttg cgacaatcct tgcaacaggt ggtaatgcca tggttaaggc ggcttattca
    37981 tgtggtaaac cagctcttgg ggtaggtgcc ggaaacgttc cagcttatgt tgaaaaatca
    38041 gcaaacattc gtcaagcagc acacgatatc gtcatgtcta aatcatttga taacggtatg
    38101 gtctgtgcat ctgaacaagc agttatcatt gataaagaaa tttacgatga atttgtagca
    38161 gagttcaaat cttaccacac ttactttgta aacaaaaaag aaaaagctct tcttgaagag
    38221 ttctgcttcg gcgtcaaagc aaacagcaaa aactgtgctg gtgcaaaatt gaacgctgac
    38281 atcgttggta aaccagcaac ttggattgca gaacaagcag gatttacagt tccagaagga
    38341 acaaacattc ttgctgcaga atgtaaagaa gttggcgaaa atgagccatt gactcgtgaa
    38401 aaattgtcac cagttattgc agttttgaaa tctgaaagcc gtgaagatgg tattactaag
    38461 gctcgtcaaa tggttgaatt taacggtctt ggacactcag cagctatcca cacagctgac
    38521 gaagaattga ctaaagaatt tggtaaagct gttaaagcta ttcgtgttat ctgtaactca
    38581 ccttctactt ttggtggtat cggggacgtt tacaatgcct tcttgccatc attgacactt
    38641 ggatgtggtt cttacggacg caactcagtt ggggataacg ttagtgccat taacctcttg
    38701 aatatcaaaa aagtcggaag acggagaaat aacatgcaat ggatgaaact tccttcaaaa
    38761 acatactttg aacgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgaacgtgtc
    38821 atgatcgtta ctgaccatgc catggtagag cttggtttcc ttgatcgtat catcgaacaa
    38881 ctggaccttc gtcgcaataa ggttgtttac caaatctttg cggatgtaga accggatcca
    38941 gatatcacaa ctgtaaaccg tggtactgag attatgcgtg ccttcaaacc agataccatc
    39001 atcgcactcg gtggtgggtc tccaatggat gctgccaaag taatgtggct cttctacgag
    39061 caaccagaag tggacttccg tgaccttgtc caaaaattca tggatatccg taaacgtgcc
    39121 ttcaagttcc cattgcttgg taagaagact aaattcatcg cgattccaac tacatctggt
    39181 acaggatctg aagtaacacc atttgccgtt atctctgata aagcaaacaa ccgtaaatac
    39241 ccaatcgctg actactcatt gacaccaact gtggcaatcg tagatcctgc tttggtattg
    39301 acagttccag gatttgttgc tgctgatact ggtatggacg tattgactca cgcgacagaa
    39361 gcatacgtat cacaaatggc tagtgactac actgatggtt tagcacttca agccattaaa
    39421 ttggtctttg aaaatctcga aagctcagtt aagaatgcag acttccactc acgtgagaaa
    39481 atgcataacg cttcaacaat cgctggtatg gcctttgcca atgccttcct aggtatttct
    39541 cactcaatgg cccataagat tggtgcgcaa ttccacacaa tccacggtcg tacaaatgct
    39601 atcttgcttc catacgttat ccgttacaac ggtacacgtc cagctaagac agcaacatgg
    39661 cctaagtaca actactaccg tgcagatgaa aaataccaag atatcgcacg catgcttgga
    39721 cttccagctt ctactccaga agaaggggtt gaatcttacg caaaagctgt ctacgaactc
    39781 ggtgaacgta ttgggatcca aatgaatttt agagaccaag gaattgacga aaaagaatgg
    39841 aaagaacatt ctcgtgaatt agccttcctg gcttatgaag accaatgttc accagctaac
    39901 ccacgtcttc caatggtaga ccatatgcaa gaaatcatcg aagatgcata ctatggctac
    39961 aaagaaagac caggacgccg taaataattg tttatcagtc tagaagcaag acaaaaactc
    40021 aatttgaggg aaagatccag taatttttct atgataaaag gcatcctatc aaggtttttg
    40081 aacacctgat aggatgcctt tttatgatat tgaggccttt ttgccctttt tgaaaaacta
    40141 gaatagaaac aaaatatata atagattgaa actggaatag tacacttctg cttctaaaac
    40201 attgttagaa ttcgatttga ctgtcctgat cgatttg
//
LOCUS       DAVLAQ010000014        38512 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000014 DAVLAQ010000000
VERSION     DAVLAQ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.014"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            261..542
                     /locus_tag="VXB71_000716"
     CDS             261..542
                     /locus_tag="VXB71_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0450862.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            674..1618
                     /gene="manA"
                     /locus_tag="VXB71_000717"
     CDS             674..1618
                     /gene="manA"
                     /locus_tag="VXB71_000717"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0450863.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1640..3115)
                     /locus_tag="VXB71_000718"
     CDS             complement(1640..3115)
                     /locus_tag="VXB71_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV0450864.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            3281..3445
                     /locus_tag="VXB71_000719"
     CDS             3281..3445
                     /locus_tag="VXB71_000719"
                     /inference="COORDINATES: protein motif:HMM:NF024803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0450865.1"
                     /translation="MVPLKSENGYRTYSQEDLERLQVILYYKYLGFSLEKIAELLKEE
                     RTDLLLHLTR"
     gene            3446..3952
                     /locus_tag="VXB71_000720"
     CDS             3446..3952
                     /locus_tag="VXB71_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TipAS antibiotic-recognition domain-containing
                     protein"
                     /protein_id="HEV0450866.1"
                     /translation="MDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFTGFSYQD
                     NQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAFNQVFQTLAQNLQVGLPATATENQ
                     EQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEFKENIDKFGSETAQYTSDAIAAYV
                     QTNAEKIG"
     gene            complement(3972..4427)
                     /locus_tag="VXB71_000721"
     CDS             complement(3972..4427)
                     /locus_tag="VXB71_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0450867.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4447..5622)
                     /locus_tag="VXB71_000722"
     CDS             complement(4447..5622)
                     /locus_tag="VXB71_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0450868.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFTGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5681..6526)
                     /locus_tag="VXB71_000723"
     CDS             complement(5681..6526)
                     /locus_tag="VXB71_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0450869.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6651..7208
                     /locus_tag="VXB71_000724"
     CDS             6651..7208
                     /locus_tag="VXB71_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0450870.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7227..7694
                     /locus_tag="VXB71_000725"
     CDS             7227..7694
                     /locus_tag="VXB71_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0450871.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7783..8412
                     /gene="upp"
                     /locus_tag="VXB71_000726"
     CDS             7783..8412
                     /gene="upp"
                     /locus_tag="VXB71_000726"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0450872.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8586..9176
                     /gene="clpP"
                     /locus_tag="VXB71_000727"
     CDS             8586..9176
                     /gene="clpP"
                     /locus_tag="VXB71_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0450873.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9255..9503
                     /locus_tag="VXB71_000728"
     CDS             9255..9503
                     /locus_tag="VXB71_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0450874.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9604..10764
                     /locus_tag="VXB71_000729"
     CDS             9604..10764
                     /locus_tag="VXB71_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0450875.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11032..11901
                     /locus_tag="VXB71_000730"
     CDS             11032..11901
                     /locus_tag="VXB71_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0450876.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11905..12861
                     /locus_tag="VXB71_000731"
     CDS             11905..12861
                     /locus_tag="VXB71_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0450877.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12861..13625
                     /locus_tag="VXB71_000732"
     CDS             12861..13625
                     /locus_tag="VXB71_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450878.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13625..14335
                     /locus_tag="VXB71_000733"
     CDS             13625..14335
                     /locus_tag="VXB71_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450879.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14749..15405
                     /locus_tag="VXB71_000734"
     CDS             14749..15405
                     /locus_tag="VXB71_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0450880.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15513..16608
                     /gene="prfB"
                     /locus_tag="VXB71_000735"
     CDS             join(15513..15584,15586..16608)
                     /gene="prfB"
                     /locus_tag="VXB71_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0450881.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16626..17318
                     /gene="ftsE"
                     /locus_tag="VXB71_000736"
     CDS             16626..17318
                     /gene="ftsE"
                     /locus_tag="VXB71_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0450882.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17311..18237
                     /locus_tag="VXB71_000737"
     CDS             17311..18237
                     /locus_tag="VXB71_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450883.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            18523..20703
                     /locus_tag="VXB71_000738"
     CDS             18523..20703
                     /locus_tag="VXB71_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0450884.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20755..21570
                     /locus_tag="VXB71_000739"
     CDS             20755..21570
                     /locus_tag="VXB71_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0450885.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGLQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21710..23053
                     /locus_tag="VXB71_000740"
     CDS             21710..23053
                     /locus_tag="VXB71_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0450886.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23270..24460
                     /locus_tag="VXB71_000741"
     CDS             23270..24460
                     /locus_tag="VXB71_000741"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0450887.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSEEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIKK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            25013..25948
                     /locus_tag="VXB71_000742"
     CDS             25013..25948
                     /locus_tag="VXB71_000742"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0450888.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25982..27019
                     /locus_tag="VXB71_000743"
     CDS             25982..27019
                     /locus_tag="VXB71_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0450889.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27192..27797
                     /locus_tag="VXB71_000744"
     CDS             27192..27797
                     /locus_tag="VXB71_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0450890.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELTAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27954..28484
                     /locus_tag="VXB71_000745"
     CDS             27954..28484
                     /locus_tag="VXB71_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0450891.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28505..29407
                     /locus_tag="VXB71_000746"
     CDS             28505..29407
                     /locus_tag="VXB71_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEV0450892.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVSCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDID
                     AACGQLRFNTMKRDRQKAVAAVNP"
     gene            29407..29889
                     /locus_tag="VXB71_000747"
     CDS             29407..29889
                     /locus_tag="VXB71_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0450893.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQPL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29891..31432
                     /locus_tag="VXB71_000748"
     CDS             29891..31432
                     /locus_tag="VXB71_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0450894.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31488..32291)
                     /locus_tag="VXB71_000749"
     CDS             complement(31488..32291)
                     /locus_tag="VXB71_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0450895.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32375..32588)
                     /locus_tag="VXB71_000750"
                     /pseudo
     CDS             complement(32375..32588)
                     /locus_tag="VXB71_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33067..33276)
                     /locus_tag="VXB71_000751"
     CDS             complement(33067..33276)
                     /locus_tag="VXB71_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450896.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33446..33718
                     /gene="rpsP"
                     /locus_tag="VXB71_000752"
     CDS             33446..33718
                     /gene="rpsP"
                     /locus_tag="VXB71_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0450897.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33738..33977
                     /locus_tag="VXB71_000753"
     CDS             33738..33977
                     /locus_tag="VXB71_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0450898.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34554..35342
                     /locus_tag="VXB71_000754"
     CDS             34554..35342
                     /locus_tag="VXB71_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0450899.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPKMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35373..35891
                     /gene="rimM"
                     /locus_tag="VXB71_000755"
     CDS             35373..35891
                     /gene="rimM"
                     /locus_tag="VXB71_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0450900.1"
                     /translation="MNYFNIGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35881..36600
                     /gene="trmD"
                     /locus_tag="VXB71_000756"
     CDS             35881..36600
                     /gene="trmD"
                     /locus_tag="VXB71_000756"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0450901.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDDPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36612..36950
                     /locus_tag="VXB71_000757"
     CDS             36612..36950
                     /locus_tag="VXB71_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450902.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36981..37301)
                     /locus_tag="VXB71_000758"
     CDS             complement(36981..37301)
                     /locus_tag="VXB71_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450903.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37399..37614
                     /locus_tag="VXB71_000759"
     CDS             37399..37614
                     /locus_tag="VXB71_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0450904.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37683..37769)
                     /locus_tag="VXB71_000760"
                     /pseudo
     CDS             complement(37683..37769)
                     /locus_tag="VXB71_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37820..38356)
                     /locus_tag="VXB71_000761"
     CDS             complement(37820..38356)
                     /locus_tag="VXB71_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0450905.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT        11855 a         7089 c         8348 g        11220 t
ORIGIN      
        1 taataaattg aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt
       61 gactgtcctg atcgatttgc cctgttcttg tttcgtttta ctatagaacg atttgaaggc
      121 gtttatgata tttagctgta cgagagtctt taaaaagtgt tttgatggtt tggatttctt
      181 ctttagttga tttcatatca ctattatata atgctttttg attttagtat agtattatcg
      241 tagaaaatgg actcggtgct atggatacac cggatgagaa tggttatgta gcagatgact
      301 atcggattac ttacttagag gcccacatca aggccatgcg agatgccatt tacaaagacg
      361 gggttgactt gcttggttat acgacatggg gctgtatcga ttcggtttca gctggcacag
      421 gggaaatgaa taagcgctat ggttttatct atgtagatcg agataatgta ggaaatggga
      481 ctctcaaacg tagcaagaag aagtccttct attggtacat gtcatttata gcaatggtgt
      541 aagcatcgag tagagcacat ttgtttacta tttttataaa atcttctccc tgctttataa
      601 gatgtaaaaa agagttcaat tcgaactctt tttttgctat aatgagggga gaaaaatcag
      661 acaggagatt aagatgtcag aaccattatt tttacaatca gttatgcaag aaaaaatctg
      721 gggtggtacc aagctacgtg atgagtttgg ctacgacatc ccaagtgaaa aagtcggaga
      781 gtactgggct atctcagctc atctaaatgg tgtttctaaa gttgccaatg gtcgttacga
      841 gggaacagat cttgctactt tgtatgcgga acaccgtgaa ttatttggca atcgtcctga
      901 gcctgtattt ccgcttttga ctaagatttt ggatgctaac gactggctca gcgttcaagt
      961 tcacccagac gatgcttatg gactagagca tgaaggcgaa cttggaaaaa cagaatgctg
     1021 gtacatcatc gctgcggatg aaggttcaga gattatctac ggccacaatg ccaagtcaaa
     1081 agaagaactc cgccagcaaa tcgaggataa gaactgggat gcgctgttga caaaagtgcc
     1141 agttaaagca ggagatttct tctatgtacc aagcggtacc atgcacgcta tcggggcggg
     1201 tatcttgatt cttgaaaccc agcagtctag cgataccact taccgtgtct atgactttga
     1261 ccgtaaggat gacaagggca atttacgtga acttcacctt gaaaaatcta tcgatgtctt
     1321 gaacattggt gaacccgcaa atagccgtcc agtgacaatc aaagcagatg atctacgttc
     1381 cactctcctt gtatccaatg atttcttcgc agtttacaaa tgggaaatta ctggaaaagt
     1441 taactttgaa aagacagctg actacagctt gttgagtgtc ttggctggtc aaggtcaact
     1501 aactgttgac gggaaaaact atccaatcca aaaagggaga cactttatcc taccaagtga
     1561 tgttgaagct tggactctgg aagggcaaga tttagaatta attgttagtc atccataaaa
     1621 aagaaagggc ctgagttcat tactcaagtc ctttttgatt acataaattg ggcgatgaag
     1681 accacgatga tgattggaat gacggaacga agaaacgaag aaggaagagc cagacttgga
     1741 acagtccttg tttccatgct ctttcatcga gatggagttc ctccattgca agagcctttt
     1801 taaagatata gcctgtaaaa agtgaaaggt agagagctcc aaatggcatg aggagattgg
     1861 gaaccaagaa gttcatagcg tcaaagaagg tcttaccaaa aatgtgaaca tccgccatga
     1921 caccgtaaga tagggctgaa ggaatgccaa agacaaaggt caaaattcct aaaataacac
     1981 tccatttggc acgtttgctg ttatcctggt tggtgatatt gcccacattg atctccagca
     2041 tcacgacaga agaagtgaca gtcgcaaaga ggaagaggac gtagaaaatg gttccaaaag
     2101 gcatcttgtc aaagagttga ggcaagacga taaagagcaa gctcggtccc ccttcagact
     2161 ggatattgaa gggggaccga gcttggaaaa tggctagacc tgccatgatg gatatcgaga
     2221 tattcatggc tacgatggag attcctgact ggactagatt ggttttcttg tccaagtaag
     2281 aagcataggt caacatgact gtaaccccta gtgagagggc aaagaaagat tgtcccagag
     2341 catagaggag accagcgcta gtcagttttg aaaagtctgg tttgaggaag taaagaaccc
     2401 cttccatggc atttggcaaa ctgagagagc gaccgatgat aacaacaaag atgataaaga
     2461 gcaggggcat catgactttc gaagctcttt caatcccttt ttgaacccca cgtgatacaa
     2521 taaagatatt taataagata aaggctgctt gagctcctag ggcaatggct ggatttgaaa
     2581 tgattgaagt aaataactga gcataatcac ccgttccacc aagttggaac aatttcccaa
     2641 actcaatacc tagatagact agaatccatc ctccgataac actgtaaaaa gataagagga
     2701 taaagagggc aaaggcgcca atccaaccga taaagttgta cttgttattc ttgcccagtt
     2761 ttccaaaggt tttgatagcg gaaacgccag cactacggcc aagggcaaac tcagccagca
     2821 ggagagggaa accgattaaa atagtggaaa tgagaaagat tagtaaaaag cctccaccgc
     2881 cattagcagc agtcatgtag ggaaacttcc aaacggaacc aagcccgatg accgagccag
     2941 cagatgctag aataaagcca agtttcgacc cccattgtga tttttctgac atagttaaac
     3001 tctgatctcc tttttcaaaa taagaaaaag ctacttgagt tgtcaaatag ccttctgttt
     3061 gattgataga cttgactatc ctattatgtt ttctaaggtc tgtcaagaaa acaattttca
     3121 agttttcaca cctttctcaa aaacgcttga ctctgaccta aggggagggg ttatactatc
     3181 attgtaagga ggaaatcatg taccatataa aagaagctgc gcagctttca ggtgtctctg
     3241 tcaagaccct gccctgcatc actatgacaa gataggactc ttggtcccct taaagtcgga
     3301 aaacggctat cgaacctata gtcaagagga tttggaacgc cttcaggtca ttctttacta
     3361 caaatatcta ggcttttctt tagagaaaat agcagaactg ttaaaggaag aaaggacaga
     3421 tttattgctc catttgacta ggtagttgga ctatctaact cgcgaaaggc aacatctgga
     3481 taccttgatt tccaccttgc aaaaaactat tcaagaacaa aaaggagaaa gaaaaatgac
     3541 cattgaggaa aaattcacgg gatttagcta tcaagacaat caaaaatacc accaagaagc
     3601 ggtagagaaa tatggtcaag aagtcatggg acaagcgctc gaacgccaaa aaggtcacga
     3661 agacgaggct acggccgcct ttaaccaagt ctttcaaact ttggcacaaa atcttcaagt
     3721 tggtttacct gcaacagcaa ccgaaaacca ggagcaagca gccaagctct tgcaagccat
     3781 tcgcacttat ggatttgact gctctattga ggtattcggt catatcggta aaggttacgt
     3841 ctacaaccca gagtttaagg aaaacattga caagtttggt tctgaaacag cccagtacac
     3901 gtcagatgcc attgcggctt acgttcagac aaatgcagaa aaaataggct aggaatttcc
     3961 tagcctattt tttacttcaa atcataaagc cagtcgtcac cgtttttgta gtaaaagaat
     4021 tcactgagat cttcttctag aaacacacga agcatatcag acatatcatc ggttgcaagt
     4081 tttagatgag aaagattttc aaagtcctcc caccaaactt tcccttcgtc tgaagactgg
     4141 agttcaccag taaagtgttc tgtcttgtaa aaaaggacga cataacgata atccttgtcg
     4201 tcataccagt ttttgatacc acagagttgg ggtttggaaa tgatcagacc agtttcttct
     4261 ttcacttcac gaatgacagc atcgacaaag gattcgccac gttcaacatg accaccagga
     4321 aaagtaatgc cagaccagtc gggactaact cggtcttgga ccaggacctt atctccgttt
     4381 ttaatcatac acatgttaac aaattcgact gcctctcttc tgttcattct tcacaacctt
     4441 taatctttaa tcataatgca gacttcccgc cacccagccg gtacagaggg cagaagtgat
     4501 gttaaagcca cccgtgtggg cattgatatc cataacttcg cctgtaaagt ggaggccagg
     4561 taccagctta ctttcaaggg ttttaggatt gatttccttg agactgactc cacccttggt
     4621 aacaaaggac tttgcaaggg acatttttcc agttacagga attttaagtt ctttaatgga
     4681 ctggacaagt tgttctcgtt ccttttcagt cagttgtttg actttttcag gatatccttg
     4741 tacaaaaaat tcggccaagc gttctggtaa caaggttttt aaagcgtttt tcaaggattt
     4801 ttcccgattt tcttctagaa atgtaaccaa gtccttctca gaaagttgag gcaaaacatc
     4861 gagtgagaga acctccccac ctttgacaaa gctagacatg cgtagggcag caggacctga
     4921 caaaccaaag tgggtaaaga gtaaatcatg agtgatgaca tgcttaccat aacttagggt
     4981 cacatcgtcc agagaaatcc cttgtaaggc tttatgtgga aaatctgtta ataaaggact
     5041 ttcagcagcc tcaagatcgg tgatggtatg cttaaaatgg cgagcaatct cgtgaccaaa
     5101 accagtcgaa ccagtcgaag gataagactt accacctgtt gtgacaatga gtttctcaca
     5161 agtgaaggtt tgatccgctg acttaaggac aaactggtca tctacttttt taacagaaac
     5221 gatttctatt tgagtagcaa cttgaccacc tagttcggtg attttctttt ccaaagcttc
     5281 gataatagtc cgagacttgt cactggctgg aaagacgcgt ccgtggtctt cgaccttaag
     5341 tttaacacca ttttctgtaa aaaagttgat gatgtcatga ttatcgaact gggagaaaac
     5401 actgtaaaga aagcgtccgt ttccaggaat tccagctagc aggttgtcta agctaccatt
     5461 gttggtcaca ttgcaacgtc ccccaccagt cccagctaat ttttttccaa gtttccgatt
     5521 tttttcgatg aggagggttt tctgtccata aaagctactg gaaatcgtag ccatcatacc
     5581 agcaggtccc ccaccgatga caatagtatc aaaatgtttc atagctctat tgtaccacaa
     5641 aaaaacaaga gatgatggtc acctcttgtc aagaatgcaa ttaatcaatt tcatagccca
     5701 tcagcaaacc gccctcttct gcatagaaac tgcagagacc agaggttggt agaattttaa
     5761 tatccgcttg tgggaaggtt tcacggattc gctctgagag ctgttgacaa catttttcgt
     5821 tattgcgttg ggccatgaca atacggccac cagcatatcc agcttttact aactcatcat
     5881 aggcagcttg aactgatttc tttgatcccc ttgctttttg tagcaattcg agagttccag
     5941 tttcactagc ttttccgacc atacgaatgt tgagaaggcc aacgaccgta ccgataagct
     6001 tgctcaaacg gccgttcttc accaagttat cgactttggc taggacaaag agcaacttag
     6061 ttttttcttg ataggcagtg atagcttcaa ccacttcttc aaaagacaag ccctggtcaa
     6121 tcaagtcatt caatttttct acgagtaggt caacttcacc accagcagat aaactatcaa
     6181 tcacatgaat cttagtgtca ggatggtctt ctagataaat attctttgct agttgagcac
     6241 tattgtgact gccagaaagg gtacctgtga tggttactag gaaaatgttt ttggcacctt
     6301 caaatgctcg caaatagtca tctgggcttg gacaagccga ttttgaagct tctgcagttg
     6361 catacatggt ttccatcatt tggtcaatat cgagactggc gtcatcaaca aagacctgat
     6421 cagctacttg aatggttaag gggacactta caaaggttgt gttaatagct ggtgttggca
     6481 gttgacgata atcacaacca gagtcagcaa taattttcca agtcatagaa attctccatc
     6541 tttgtcagtt atacattgac aaaggttctg tcttttttta caattatatc atgaaaaccc
     6601 ttgaaacaaa agcatcatcc gtctgttgtg acaagtagaa agaaaatgtt atgtctgaac
     6661 gtagaatctc tgaaaagtct cttgaaaatc tcagaaaatc aaaccaagaa tccaatttat
     6721 taaccagaga agccattgaa acagccctct tgcaactctt ggaaaaaaag gagctgacca
     6781 agattagtat ttctgaattg gtcaaacgtg caggtgtttc gcgtgcggcc ttttatcgca
     6841 attatgactc caaagaggaa attttagaga gcgtctttaa acgaactgtc cacaatatta
     6901 tggaacagct gcatcattac gatttaaaga cagaccttta tttggtttgg gttcaccttt
     6961 tccgggaggc cagaaaggaa gctagagtga ttcaattggc cttggattac catctggaaa
     7021 aaatctttgt ccaagccatg caggaatttc tagaaaaata ccatgggaaa tcaaaaggtg
     7081 tcagctctta tcttcattcc ttctggagct cagccatcgt ctctgtcctt ctaaaatgga
     7141 tcaaggatgg catgaaggta ccagctgaaa agattgcaga tttaggttta ccatttttta
     7201 aaaaatagag aaaaaggaga aaagagatga ctgaaaaaag actggcctgg gatgagtatt
     7261 ttgcagccca agccctacta attgcgaatc gttccacttg taaacgtgct aaagtgggcg
     7321 cgattctggt aaaagataat aaggttattt ccactggtta caatggttcg gtgtcaggga
     7381 ctgagcattg tattgatcac gaatgtttgg tcattgaagg ccactgtgtt cgcacccttc
     7441 acgctgaggt caatgctatc cttcaaggtg ctgagcgtgg tgttcccaaa ggctttacag
     7501 cctatgtaac ccattttcct tgtctcaact gtacaaaaca attgcttcag gtcggctgca
     7561 agcgcgtggt ttatatcaac cagtaccgaa tggacgacta cgcccaatac ctttatcaag
     7621 aaaaagggac agaattgacc catttaccac ttgagacagt acagacagct cttaaagagg
     7681 ctgatctaat gtaaaaatta tcaaaaataa atggcttaga aagattttta aaccgttttt
     7741 tggtataata agaagaataa attgaaagaa ggaattccaa aaatgggaaa aattgaagtt
     7801 attaatcacc cactgattca acacaaattg tcaatcttgc gtcgtacaga tacttctaca
     7861 aaagcttttc gtgagctagt agatgagatt gcaatgttga tggggtatga agtacttcgt
     7921 gatcttccac tagaagatgt ggaaatcgaa acaccaatta caaaaacagt tcaaaaacaa
     7981 ttggcaggta agaaattggc catcgtccca atcttgcgtg caggtatcgg gatggttgat
     8041 ggtctcttga gcttggttcc agctgctaaa gttggccaca tcggtatgta ccgtgatgaa
     8101 gaaacacttc aaccagttga atacttggtg aaattgcctg aggacattga ccaacgtcaa
     8161 atttttatag tagacccaat gttggcaaca ggtggctcag caatcttggc tgttgattct
     8221 cttaaaaaac gtggcgcatc aaatatcaaa tttgtctgcc ttgtatctgc tccagagggt
     8281 gtaaaagccc ttcaagaagc tcatccagat gtagaaatct ttacagcagc cttggatgaa
     8341 cgtttgaacg aacacggtta tatcgttcca ggtcttggag atgctggaga ccgcttgttc
     8401 ggtacaaaat aagatcgaaa agaagaatga cttggaaaag tatttccagt cacgaaagga
     8461 ggttgggttt ttgtttctgt ctaatgaaag cagagcaaaa atttgacctt ttttgaccaa
     8521 gatattataa tagtcttatc ttcagtcatt tgaccaacaa aattaaaact caaaaggaga
     8581 aatgaatgat tcctgtagtt attgaacaaa caagccgtgg agaacgttct tacgatattt
     8641 actcacgtct tctcaaagac cgcatcatta tgctgacagg tccggttgaa gacaatatgg
     8701 ctaactctgt tattgcccaa ttgcttttct tggatgccca agatagtaca aaagatattt
     8761 acctttatgt caatacacca ggtggttctg tttcagctgg tttggcaatc gtagatacca
     8821 tgaactttat caaggcagat gtccaaacca ttgttatggg aatggctgca tctatgggaa
     8881 cagtcatcgc atcaagtgga gcaaaaggca aacgtttcat gcttccaaat gctgaataca
     8941 tgattcacca accaatgggc ggtacaggtg gtggtaccca acaaactgat atggctatcg
     9001 ctgcagaaca cttgctcaaa actcgtaata ccttggaaaa aatcttggct gaaaattcag
     9061 gtcagtcaat ggaaaaagtc catgcagatg cagaacgtga taactggatg agcgcccagg
     9121 aaacacttga atatggcttt attgatgaaa ttatggccaa caattcattg aactaatgat
     9181 gatagaaggc aaactcgact gggtttgctt tttttggtat aatagggaga gatttcttag
     9241 aaagaggatt tatcatgttt gaaaaagtca atcgctctgg cttgattatc tatctttact
     9301 ataatcgtga tgccaaaaaa ctgcaggatt atggagatat tacctatcat tccaagaaac
     9361 atcgttactt acaactctat gttccaactc aagaagtgga gcaattggtc ggacgcttga
     9421 gcaaggaaaa atttattaaa aaagttaggg tttgtcatat ccaagagttg gaaacaccct
     9481 ttgtgggcaa tctttatcga taggaaaacg ttatcatcga aaaagttcaa ggaaaacatt
     9541 gacaattttc tgataattcg gtatattctt aacagactat ttaagaaata aggagacaaa
     9601 aagatgaaga aaaaatttgc cctatcgttt gtggcgcttg caagtgtagc acttcttgca
     9661 gcctgtggag aagtgaagtc tggagcagtc aacactgctg gtaactcagt agaggaaaag
     9721 acaattaaaa tcgggtttaa ctttgaagaa tcaggttctt tagctgcata cggaacagct
     9781 gaacaaaaag gtgcccaatt ggctgttgat gaaatcaatg ccgcaggtgg tatcgatgga
     9841 aaacaaatcg aagtagtcga taaagataat aagtctgaaa cagctgaggc tgcttcagtt
     9901 acaactaacc ttgtaaccca atctaaagta tcagcagtcg taggacctgc aacatctggt
     9961 gcgactgcag ctgcggtagc gaacgctaca aaagcaggtg ttcccttgat ctcaccaagt
    10021 gcgactcaag atggattgac taaaggtcaa gattacctct ttattggaac tttccaagat
    10081 agcttccaag gaaaaattat ctcaaactat gtttctgaaa aattaaatgc taagaaagtt
    10141 gttctttaca ctgacaatgc cagtgactat gctaaaggga ttgccaaatc tttccgcgag
    10201 tcatacaagg gtgaaatcgt tgcagatgaa actttcgtag caggtgacac agacttccaa
    10261 gcagccctta caaaaatgaa agggaaagac tttgatgcta tcgttgttcc tggttactat
    10321 aatgaggctg gtaagattgt aaaccaagcg cgtggtatgg gaattgacaa accaatcgtt
    10381 ggtggtgatg gattcaacgg tgaggagttt gtacaacaag caactgctga aaaagcatca
    10441 aacatctact ttatctcagg cttctcaact actgtagaag tttcagctaa agctaaagcc
    10501 ttccttgacg cttaccgtgc taagtacaat gaagagcctt caacatttgc agccttggct
    10561 tatgattcag ttcaccttgt agcaaacgca gcaaaaggtg ctaaaaattc aggtgaaatc
    10621 aaggataacc ttgctaaaac aaaagatttt gaaggtgtaa ctggtcaaac aagcttcgat
    10681 gcagaccaca acacagtcaa aactgcttac atgatgacca tgaacaatgg taaagttgaa
    10741 gcagcagaag ttgtaaaacc ataatagaaa aatgttgaaa tagggaatga gcctttgact
    10801 cactccctgt ttcgatattt aatactcttc gaaaatctct tcaaactgcg tcaacgtcgc
    10861 cttggattat atatgtgact gacttcgtca gtcttatcta caacctcaaa gcagtgcttt
    10921 gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta taagaaccta
    10981 tcaaaaagtg agggaaaccc ctcggaatta taaatagaaa gagtgaatct tatgctccaa
    11041 caactcgtaa atggtttgat tctaggtagt gtttacgcgc tgttagccct aggatatacc
    11101 atggtttacg gaattatcaa gctcatcaac ttcgcccatg gtgatattta tatgatggga
    11161 gcctttatcg gttatttctt gatcaattct ttccaaatga atttctttgt agcgcttatt
    11221 gtagctatgc tagcgacagc tattcttggt gtcgtgattg agtttcttgc ttaccgacct
    11281 ttgcgccact ctactcgtat tgctgttttg attacggcta ttggggtttc tttcctattg
    11341 gagtatggaa tggtctatct ggttggtgcc aatacccgtg ccttccctca agcgattcaa
    11401 acagttcgat atgatttggg accaattagc ttaacaaatg tgcagttaat gattttggct
    11461 atttccttga ttttgatgat tttgttacaa gtcattgtcc aaaagactaa gatggggaaa
    11521 gccatgcgtg cagtatcagt agatagcgac gcggcgcaat tgatggggat caatgtaaac
    11581 cgtacgatta gctttacctt cgctttgggt tctgctcttg cgggtgcggc tggtgttctg
    11641 attgctcttt attataactc tcttgagcct ttgatggggg ttactccagg tcttaaatct
    11701 ttcgttgccg cagtacttgg tggtatcgga attattcctg gtgcggctct tggtggcttt
    11761 gtgattggtc tattggaaac ctttgcgact gcctttggga tgtcagattt ccgtgatgcc
    11821 attgtttatg gaatcttgtt gttgatcttg attgtccgcc cagctggtat ccttggtaag
    11881 aatgtgaaag agaaggtgta aacgatgaag gaaaatttaa aagttaatat tctatggtta
    11941 ctccttttgt tagctggcta tagcttgatt agtgtactgg tttcagtcgg agtacttaat
    12001 ctattctatg tacagatttt acagcaaatt ggaattaata ttattttggc tgttggtctc
    12061 aacttaatcg ttggtttttc aggacaattt tcacttggtc atgctggttt catggcgatt
    12121 ggtgcctatg cagcagctat tattggttct aaattaccaa cctacggtgc cttctttgga
    12181 gctatgcttg taggggcttt gctttcagga gcagttgcct tacttgtcgg cattccaacc
    12241 ttgcgcttga agggggacta tcttgcggta gcaactctgg gtgtttctga aattatccgt
    12301 atctttatca tcaatggtgg aagccttaca aatggtgcgg caggtatctt agggattcct
    12361 aactttacaa cttggcaaat ggtttacttc tttgtcgtga ttacaaccat tgcaaccttg
    12421 aacttcttgc gtagcccaat tggtcgttca accctctctg ttcgtgaaga tgaaatcgct
    12481 gctgagtcag ttggggttaa tacgactaaa attaaaatca tcgcttttgt ctttggtgcc
    12541 attactgcaa gtattgctgg gtcacttcag gcaggattta tcgggtctgt tgtaccgaaa
    12601 gattacacct tcatcaactc aatcaacgtt ttgattattg ttgtatttgg tggactcggt
    12661 tccattacag gtgcgattgt ttcggctatt gttctgggaa ttttgaatat gcttctccaa
    12721 gatgttgcta gtgtgcgtat gattatttac gctttggcct tggtattggt aatgattttc
    12781 agaccaggtg gactccttgg aacatgggaa ctgagcctat cacgtttctt taaaaaatct
    12841 aagaaggagg aacaaaacta atggcattac ttgaagtaaa acagttaacc aaacattttg
    12901 gtggtctaac agctgttgga gatgtgactc ttgaattgaa cgaaggggaa ctggttggat
    12961 taatcggtcc aaacggagct gggaaaacca cccttttcaa ccttttgacc ggtgtttatg
    13021 aaccaagcga gggaacagta accctagatg gtcacctttt gaatgggaaa tcaccttata
    13081 agattgcctc tttgggactt ggacgtactt tccaaaatat ccgtctcttt aaagatttaa
    13141 cagttttaga caatgttttg attgcttttg gaaaccatca caaacaacat gtttttacta
    13201 gtttcttacg cttaccagct ttttacaaga gtgaaaaaga attaaaggct aaagctttgg
    13261 aattgttgaa aatctttgat ttagatggtg atgcagagac tcttgctaaa aatctttcct
    13321 acggacaaca acgtcgtttg gaaattgttc gtgcccttgc tacggaacct aaaattctct
    13381 tcttagatga accagcagca ggtatgaacc cacaggaaac agccgaattg actgagttaa
    13441 ttcgtcgtat caaagatgaa tttaagatta caatcatgtt gattgaacac gatatgaatc
    13501 tggtcatgga agtaacagaa cgtatctacg tacttgaata tggccgttta attgctcaag
    13561 gaactccaga cgaaattaag accaataaac gcgttatcga agcttatcta ggaggtgaag
    13621 cctaatgtct atgttaaaag ttgaaaatct ttctgtgcat tacggtatga tccaagcagt
    13681 ccgtgatgta agctttgaag ttaatgaagg agaagttgtt tcccttatcg gtgccaacgg
    13741 tgcaggtaag acaactattc ttcgcacctt gtcaggtttg gttcgaccaa gttcaggaaa
    13801 gattgaattt ttaggtcaag aaatccaaaa aatgccagct cagaaaattg tggcaggtgg
    13861 tctttcacaa gttccagaag gacgccacgt ctttcctggc ttgactgtta tggaaaatct
    13921 tgaaatggga gctttcttaa agaaaaatcg tgaagaaaat caagctaact tgaagaaggt
    13981 tttctcacgc tttcctcgtc ttgaagaacg taagaaccaa gatgcagcta ctctttcagg
    14041 aggggaacaa caaatgcttg ccatgggacg cgctcttatg tcaacaccaa aacttcttct
    14101 tttagatgaa ccatcaatgg gacttgcccc aatcttcatc caagagattt ttgatatcat
    14161 tcaagatatt cagaagcaag gaacaaccgt cctcttgatt gaacaaaatg ccaataaagc
    14221 acttgcaatc tctgaccgag gatatgtact ggaaacaggg aaaatcgtcc tatcaggaac
    14281 aggaaaagaa ctcgcctcat cagaagaagt cagaaaagca tatctaggtg gctaaaacaa
    14341 tccagtggat tgttttagtc ggcagatgaa gattacgaag taatcatcat tatagtctgg
    14401 gagactagtt taggttgcag ataaagattg cgaagcaatc atcaaatcca gtggattgtt
    14461 ttagtcggca gatggagatt acgaagtaat catcaatata gtccggggga cctttttagt
    14521 cggtagattg agattgcaaa caaatctgca tctacattga aagcttaatt tctaataatt
    14581 gaaaaaatcg aatgaaaaat ttcttacctt cattcacaga gctcgatttc agagctcttt
    14641 ttgctagctt attcatactt ttctgaattt cgaaaaagaa atgtaagcgt ttgatagatt
    14701 tacaaaaaga ttgtataata gggataagaa tagaaaagga gaagtctcat ggcagttaaa
    14761 gattttatga cccgcaaggt agtttatatt agtccagata caacagtatc tcatgcagca
    14821 gatttgatga gagagcaagg tttgcaccgt ctgcctgtta tcgaaaatga tcaattagtt
    14881 ggtttggtga ctgagggaac cattgcacaa gcaagtccat ctaaagcaac aagtctttct
    14941 atctatgaga tgaattatct tctgaataag acaaaagtaa aagatgtcat gattcgcgat
    15001 gttgtcactg tctcaggcta tgctagtcta gaagatgcaa cttatctgat gttgaaaaat
    15061 aagattagta ttctccctgt cgtagataac catcaagtat acggagttat tactgaccgt
    15121 gacgttttcc aagcctttct tgaaattgca ggttatggcg aagaagggat tcgtgtacgc
    15181 tttgttacag aagatgaagt tggtgttctt ggaaaaattg tttctttgat tgtagaagaa
    15241 aatttgaata tctcccatac agtcaatatt ccgcgtaagg atggtaaggt gattatcgaa
    15301 gtgcaaatcg atggatcaat tgatttacca gccttgaaag aaaaatttga agcaaatggt
    15361 attcaagtgg aagaaatcgc tcgcacttca gcaaaagtct tgtaagaagg gaagcccaaa
    15421 ggcttctttt ttcatgaaaa ggggattaga gaaaaagatg gaaagaaatg ataaaatatg
    15481 ctataatgaa ataatgtaaa aaaggagtat ttatggacat ttcagtaatt cgtcagaaaa
    15541 ttgacgcaaa tcgtgaaaaa ttagcttctt tcagggggtc tctttgacct cgaagggcta
    15601 gaggaggaga ttgccatctt ggaaaacaag atgacagaac ctgatttttg gaacgataat
    15661 attgcagccc aaaaaacgtc gcaagaatta aatgaattaa aaaacactta caataccttc
    15721 cataagatgg aagagttgca ggatgaagtc gaaattttat tggatttttt ggctgaagac
    15781 gagtcagtgc atgatgaact ggtagcgcag ttagccgaac ttgataagat aatgaccagc
    15841 tacgagatga ctctactctt gtcagaacct tatgaccaca acaatgccat cttggaaatc
    15901 catccaggtt ctggtggtac tgaggcgcag gactggggtg atatgttgct tcgtatgtat
    15961 actcgttatg gtaatgctaa aggctttaaa gtggaagtgt tggattacca agcaggtgat
    16021 gaggctggta ttaagtcggt aactttatca tttgaagggc ctaatgccta tggtctcctc
    16081 aagtcagaaa tgggtgttca ccgcttagtg cgaatctcac catttgactc tgccaaacgt
    16141 cgccatacct ctttcacatc tgtagaagtg atgccagaat tggatgatac tattgaagtg
    16201 gaaatccgtg aagatgatat caagatggat accttccgtt caggtggtgc cggtggacaa
    16261 aacgtcaata aggtttcaac aggtgtacgt ttaacccaca ttccaactgg aattgttgtc
    16321 caatcaacag tggatcgtac ccagtatgga aatagagatc gtgccatgaa gatgttgcag
    16381 gctaagctct atcaaatgga gcaagagaag aaggctgcag aggtagattc tctcaaaggt
    16441 gagaaaaagg agatcacttg gggaagccaa atccgttctt atgtcttcac gccttatact
    16501 atggtaaaag atcaccgaac tagctttgag gttgctcagg tagataaggt tatggatggg
    16561 gacttagatg gttttatcga tgcttatctc aagtggcgaa ttagctaaga tagaaaggaa
    16621 ctcacatgtc aattattgaa atgagagatg tcgttaaaaa atacgacaac ggaacgactg
    16681 ctctacgcgg tgtttcggtt agcgttcaac cgggggaatt tgcttacatc gtaggacctt
    16741 caggagcagg gaagtcaact tttattcgtt ctctgtatcg tgaagtaaaa atcgataaag
    16801 gaagcctatc agttgctggt tttaatctgg ttaagatcaa aaagaaagat atcccgcttc
    16861 tacgtcgtag tgttggggtt gtcttccagg attataaatt gttaccaaag aaaactgtct
    16921 atgaaaatat tgcttacgct atggaagtaa tcggggaaaa tcgccgtaat atcaaaagac
    16981 gagtgatgga agttttggac ttggttggat tgaagcataa ggttcgttct ttcccaaatg
    17041 aactctcagg tggggagcaa cagcggattg cgattgcgcg tgcaattgta aataatccca
    17101 aagtattgat agctgatgag ccaacaggaa atctggatcc ggataattca tgggaaatta
    17161 tgaatctttt ggaacggatt aacctacaag gaacaactat tttgatggcg actcataata
    17221 gccagattgt aaataccttg cgccaccgtg tcattgccat tgaaaatggc cgtgtcgttc
    17281 gtgacgaatc aaaaggagag tatggatacg atgattagta gattttttcg ccatttattt
    17341 gaagccttaa aaagtttgaa acgaaatggt tggatgacag tagctgctgt cagttcagtc
    17401 atgattactt tgaccttggt ggcaatattt gcatctgtta ttttcaatac agcgaaacta
    17461 gctacagata ttgaaaataa tgtccgtgta gtagtttata tccgaaagga tgtggaagat
    17521 aatagtcaga caattgaaaa agaaggtcaa actgttacaa ataatgacta ccacaaggta
    17581 tatgattctt tgaagaacat gtctacggtt aaaagtgtta ccttttcaag taaagaagaa
    17641 caatatgaaa aattaaccga gataatggga gataactgga aaatctttga aggagatgcc
    17701 aatcctctct atgatgccta tattgtagag gcaaacactc caaatgatgt aaaaactata
    17761 gccgaagatg ctaaaaaaat tgaaggtgtc tctgaggttc aagatggcgg tgccaataca
    17821 gaaagactct tcaagttagc ttcatttatc cgtgtttggg gactagggat tgctgctttg
    17881 ttaattttta tcgcagtttt cttgatttca aataccattc gtattaccat tatttcccgc
    17941 agtcgcgaaa ttcaaatcat gcgcttggtc ggagctaaaa acagttatat ccgtggaccg
    18001 ttcttgttag aaggagcctt tatcggttta ttgggagcta tcgcaccatc tgttttggtc
    18061 tttattgttt atcaaattgt ttaccaatct gtcaacaaat cgttggtagg gcaaaatcta
    18121 tccatgatta gtccagattt atttagtccg ttgatgattg ccctactatt tgtgattggg
    18181 gttttcattg gttcattggg atcaggaata tccatgcgcc gattcttgaa ggtttaggta
    18241 aaatagctgc ttttatgagg agattgtaaa atctcctttt ttgctacaag agtttttgaa
    18301 aagagatgcg cagaagaaaa gagcttccaa agaagtcccc cagagaagac ttcttgatgg
    18361 ctaatttgaa cttgaaattt ggcgcactag aaatttttta gaaaaaagtg taattttttt
    18421 ataaaagcct ttacaaaaaa aattaaagtg gtataattaa atcatagaaa gtgcaaacgt
    18481 tttcgtaaaa cgtttgccta aataaaaata aaggagattt gaatgatgaa agatacattc
    18541 aaaaatgtct tgtctttcga attttggcaa aaattcggta aggctttgat ggtagttatc
    18601 gcggttatgc cggctgctgg tttgatgatt tcaatcggta agtctatcgt gatgattaac
    18661 ccaacctttg caccacttgt catcacaggt ggaattcttg agcaaatcgg ttggggggtt
    18721 atcggtaacc ttcacatttt gtttgcccta gccattggag gaagctgggc taaagaacgt
    18781 gctggtggtg ctttcgccgc tggtcttgcc ttcatcttga ttaaccgtat cactggtaca
    18841 atctttggtg tatcaggcga tatgttgaaa aatccagatg ctatggtaac tactttcttt
    18901 ggtggttcaa tcaaagttgc tgattacttt atcagtgttc ttgaagctcc agccttgaac
    18961 atgggggtat tcgtagggat tatctcaggt tttgtagggg caactgctta caacaaatac
    19021 tacaacttcc gtaaacttcc tgatgcactt tcattcttca acgggaaacg tttcgtacca
    19081 tttgtagtta ttcttcgttc agcaatcgct gcaattctac ttgctgcttt ctggccagta
    19141 gttcaaacag gtatcaataa cttcggtatc tggattgcca actcacaaga aactgctcca
    19201 attcttgcac cattcttgta tggtactttg gaacgtttgc tcttgccatt tggtcttcac
    19261 cacatgttga ctatcccaat gaactacaca gctcttggtg gtacttatga cattttaact
    19321 ggtgcagcta aaggtactca agtattcggt caagacccac tatggcttgc atgggtaaca
    19381 gaccttgtaa accttaaagg tactgatgct agtcaatatc aacacttgtt agatacagta
    19441 catccagctc gtttcaaagt tggacaaatg atcggttcat tcggtatctt gatgggtgtg
    19501 attgttgcta tctaccgtaa tgttgatgct gacaagaaac ataaatacaa aggtatgatg
    19561 attgcaacag ctcttgcaac attcttgaca ggggttactg aaccaatcga atacatgttc
    19621 atgttcatcg caacacctat gtatcttgtt tactcacttg ttcaaggtgc tgccttcgct
    19681 atggctgacg tcgtaaacct acgtatgcac tcattcggtt caatcgagtt cttgactcgt
    19741 acacctattg caatcagtgc tggtattggt atggatatcg ttaacttcgt ttgggtaact
    19801 gttctctttg ctgtaatcat gtactttatc gcaaacttca tgattcaaaa attcaactac
    19861 gcaactccag ggcgcaacgg aaactacgaa actgctgaag gttcagaaga aaccagcagc
    19921 gaagtgaaag ttgcagcagg ctctcaagct gtaaacatta tcaaccttct tggtggacgt
    19981 gtaaacatcg ttgatgttga tgcatgtatg actcgtcttc gtgtaactgt taaagatgca
    20041 gataaagtag gaaatgcaga gcaatggaaa gcagaaggag ctatgggtct tgtgatgaaa
    20101 ggacaagggg ttcaagctat ctacggtcca aaagctgaca ttttgaaatc tgatatccaa
    20161 gatatccttg attcaggtga aatcattcct gaaactcttc caagccaaat gactgaagca
    20221 caacaaaaca ctgttcactt caaagatctt actgaggaag tttactcagt agcagacggt
    20281 caagttgttg ctttggaaca agtaaaggat ccagtatttg ctcaaaaaat gatgggtgat
    20341 ggatttgcag tagaacctgc aaatggaaac attgtatctc cagtttcagg tactgtgtca
    20401 agcatcttcc caacaaaaca tgcttttggt attgtgacgg aagcaggtct tgaagtattg
    20461 gttcacattg gtttggacac agtaagtctt gaaggtaaac catttacagt tcatgttgct
    20521 gaaggacaaa aagttgcagc aggagatctc cttgtcacag ctgacttgga tgctatccgt
    20581 gcagcaggac gtgaaacttc aacagtagtt gtcttcacaa atggtgatgc aattaaatca
    20641 gttaaattag aaaaaacagg ttctcttgca gctaaaacag cagttgctaa agtagaattg
    20701 taatatactt gaggttggaa gctgtattcc aacctcttat tttgggagaa aagaatgaaa
    20761 tttttaacac tcaatactca cagttggatg gagaaagaag cagaggaaaa attccagatt
    20821 ttgcttgaag atattcttga aaaggactat gatttgattt gtttccaaga aatcaatcag
    20881 gagatgacct cgtcagaggt ggaggttaat gacctttatc aagctttgcc agcagctgag
    20941 cctattcacc aagaccatta tgttagactc ttggttgaaa agttgttaga gcaagggaaa
    21001 aattactact ggacctgggc ttataaccat atcggctatg accgctacca cgaaggtgtg
    21061 gctatcttgt ctaaaacacc tattgaagcc agagaaattt tggtttcaga tgtggatgat
    21121 ccaacagact atcatactcg ccgtgttgcc ctagctgaaa ctgtagtcga tggcaaggag
    21181 ctagcagttg ccagtgttca tctctcttgg tgggataaag gtttacaaga agaatgggca
    21241 cgatttgagg ctgtcttgaa aaaattgaac aagccacttt tactagctgg agattttaac
    21301 aacccagcag gtcaggaagg ttaccaagct attttagcta gtccattagg cttacaagac
    21361 gcatttgaag ttgctcaaga gaaaagtggt agctatactg ttccgcctga aattgatggc
    21421 tggaaaggga acactgaacc ccttcgaatc gattatgtct ttactaccaa agagttagcg
    21481 gtggaaaatt tacatgtcgt atttgatggt aacaagagtc cacaagtgag tgatcactat
    21541 ggcttgaatg ctatattaaa ctggaaataa taactgaaaa gaggttggaa ctataaaatt
    21601 ccagcctttt cttactagag aagctactgg aaatagccta aataagtgag actactgtaa
    21661 tggaataaaa tatggtataa ttgataaggt agatagaatc gaggatgtta tgtcatttac
    21721 gaaatttcaa tttaaaaact atattagaga agccttgaag gagttaaaat ttacaactcc
    21781 aacagaggtg caagacaagt tgattcctat tgttttggca ggtcgtgacc tagtaggaga
    21841 atcaaaaaca ggttcaggta agactcatac tttcttgtta ccgattttcc agcaattaga
    21901 tgaagctagc gatagtgtac aagcagtgat tactgcaccg agtcgtgagt tggctactca
    21961 aatttaccaa gtagcgcgtc agatttcagc tcactcagat gtcgaagttc gtgtggttaa
    22021 ttatgtgggt ggtacggata aggctcgcca gattgagaaa ttggcaagca atcagcctca
    22081 tattgttatt ggaacaccag gccgtatcta cgacttggtt aaatctggtg atttagctat
    22141 tcataaagcc aagacatttg ttgttgatga agcagatatg accttggata tgggattctt
    22201 ggaaactgtt gataagattg ctggcagtct tccaaaagac ttgcaattca tggtcttctc
    22261 agcgactatc ccacaaaaac tgcaaccatt cttgaaaaaa tacttatcaa atcctgttat
    22321 ggagaaaatt aagaccaaaa cggttatttc tgacaccatt gataattggt tgatttcgac
    22381 caagggacat gataagaatg ctcaaattta ccagttgact cagttgatgc agccgtattt
    22441 ggcaatgatt tttgttaaca ctaaaacacg tgctgatgaa ttgcattcat atctgactgc
    22501 tcaaggcttg aaggttgcaa aaatccatgg agatattgcc cctcgtgaac gcaagcgaat
    22561 catgaatcag gtgcaaaatc tggattttga gtatattgtc gcaacagatt tggcagcgcg
    22621 tgggattgac attgaaggtg tcagccatgt catcaatgat gccattccgc aagacttatc
    22681 tttttttgtt catcgtgttg gtcgtactgg acgaaatggc ctaccaggta cagctattac
    22741 cctttatcag ccaagtgatg actcggatat ccgtgagttg gagaaattgg gaatcaagtt
    22801 tagtcctaag atggtcaaag acggggaatt tcaagatacc tatgaccgtg atcgtcgtgc
    22861 caaccgtgag aaaaaacaag ataaacttga tatcgaaatg attggtttgg ttaaaaagaa
    22921 aaagaaaaaa gtcaaaccgg gttataagaa gaaaattcaa tgggcggttg atgaaaagcg
    22981 ccgtaaaacc aagcgtgctg aaaatcgcgc tcgcggtcgt gcagagcgta aagctaaacg
    23041 ccaaacattt taatagaaat tgttggagta ttgagctcca acttttttat ttatgagaac
    23101 gaactatcta aaccgaaaca ctacattaaa gactgcaaat tgcgattaaa aatggtataa
    23161 tgataaagtt atatagtccc gataagatgg taggtattta ttacgaagag ttttcctatc
    23221 agtactttgt aactctataa caatattttt taaggggggg gacattttta tgtcagagcg
    23281 taaattattc acgtctgaat ctgtatctga ggggcatccg gataagattg cagaccaaat
    23341 ttcagatgcg attttggatg ctattttagc aaaggatcca gaggcgcacg ttgctgctga
    23401 aacagctgta tatactggtt ctgtccacgt ttttggtgaa atttctacaa atgcctatgt
    23461 ggatattaac cgtgtggttc gtgataccat tgcagagatt ggttatacca atacagaata
    23521 tggattttct gctgagacgg tgggagtaca cccatctttg gtggaacaat ctcctgacat
    23581 cgctcaaggt gttaacgaag ccttggaggt tcgtggaaat gctgatcaag atccactgga
    23641 cttgattgga gcaggtgacc aagggctcat gtttggattt gcagtagatg aaacagaaga
    23701 gctcatgcca ttgccaattg cactcagtca taaattggtt cgtcgtctgg cagaacttcg
    23761 taagtctgaa gaaattagct atctccgtcc agatgcaaaa tcacaagtta cagttgagta
    23821 cgatgaaaat gaccgtccgg tacgtgtaga tacagtcgtt atttctactc agcatgatcc
    23881 agaggccact aatgaacaaa tccatcaaga tgtgattaaa aaggtcatca aagaagttat
    23941 tccatcttct tatcttgatg ataagacaaa attctttatc aatccgacag gtcgttttgt
    24001 aatcggtggt cctcaagggg actcaggttt gactggtcgt aagattattg tagatactta
    24061 tggtggctac tctcgtcatg gtggtggtgc cttctctggt aaagatgcga ctaaggtgga
    24121 tcgttcagcc tcttatgcgg ctcgctatat tgccaagaat atcgttgcag cagaccttgc
    24181 taagaaggca gaagtgcagt tggcctatgc tatcggtgtt gcgcaacctg tttctgttcg
    24241 tatcgatact ttcggtacag gaacagtagc tgaaagtcaa cttgaaaaag cggctcgtca
    24301 aatctttgac cttcgccctg cagggattat ccaaatgctg gacctcaagc gtccaattta
    24361 ccgtcaaaca tcggcttacg gtcacatggg acgtacagat attgatcttc catgggaacg
    24421 tttggataag gtagatgctt tgaaagaagc agtaaaataa gattttaaga ggggaacgtc
    24481 ctctcttttt tatagttttt aactatactg ggatactgtt ctgaaaatcc attttgtgaa
    24541 agtagagatt tacatgtata gtagattgaa actagaatag tacacctcaa cttctaaaac
    24601 attgttagaa atcgatttga ctgtcctgat tgatttctcc tgttcttgtt tcattttact
    24661 atatttcttt aaaaatgata aaggttgaga tttctcctcg taatagataa tcatggggat
    24721 atttcaatcc aaagttttat tcgttatcac ttgactattg caaggttttc tagagcaaca
    24781 gagtcatgga atggactcat ggttgagatt tctccttgtt gcttggactt cattcaaaag
    24841 tctgttaccc aagccttgtt caaacttcca atacactagc tgtttccata gcatgacttc
    24901 tgtactagac tttcttttcc gaataaatag atagaaccac agaatctagt aaacctagaa
    24961 ttaaaattat ggtataatat tagcaataaa agaaatctgg aggattagaa tcatggtatc
    25021 aacgaaaaca caaattgctg gttttgagtt tgacaattgc ttgatgaatg cagcaggtgt
    25081 ggcttgtatg acgatagagg agttagaaga ggtcaaaaac tcagcggcag gaacctttgt
    25141 tactaagaca gcgaccttgg acttccgtca ggggaatcct gagccacgct accaagatgt
    25201 tccacttggt tccatcaact ctatgggctt gccaaataat ggcttagact attatttgga
    25261 ttatctttta gatttgcagg aaaaagagtc gaaccgaact ttcttcttat ctctggtcgg
    25321 catgtctcca gaggaaaccc atactatttt gaaaaaagtc caagagagtg attttcgtgg
    25381 tctgactgag ctaaatcttt cctgtccaaa tgttccaggt aaacctcaga ttgcctatga
    25441 ttttgagaca acagaccgga ttttggcaga agtgtttgct tacttcacca aacctcttgg
    25501 aattaaattg ccaccttatt ttgatattgt tcactttgat caagcggcag ctattttcaa
    25561 caaatatccg ctcaagtttg tcaactgcgt taactctatc ggaaacggcc tctatataga
    25621 agacgaatct gtcgttattc ggcctaagaa tggttttggt ggaattggtg gagaatacat
    25681 caaaccgact gctctagcca atgttcacgc cttttatcaa cgtttaaatc ctcaaatcca
    25741 aattatcgga acaggtggcg ttctgactgg tcgagatgcc tttgaacaca tcctctgtgg
    25801 agcaagtatg gtgcaggtgg gaacgaccct tcacaaagaa ggtgtcagtg cttttgaccg
    25861 cattaccaat gaactgaaag caatcatggt ggaaaaaggc tacgagagct tagaagattt
    25921 ccgtgggaaa ttgcgctata ttgactaaat taaatcgaaa aatctgaaga aaggagagac
    25981 gatgctagcc attgaagaaa gtcagaagtt gactttatca aatttaccga gcctgagcct
    26041 atttacaggg acagatcagg gtcagtttga agtgatgaag agtcaagtgt tgaaacagat
    26101 tgggtatgat tctgctgacc tcaactttgc ctactttgat atgaaagaag tagtttacaa
    26161 ggatgtggaa ctggagttgg tcagccttcc tttctttgcg gatgagaaaa tcgtgatatt
    26221 agattatttt atggatatca cgactgctaa gaaacgcttt ttgacagatg atgagcttaa
    26281 gtcatttgag gaataccttg acaatccttc tccaacaacc aagttgataa tctttgcaga
    26341 aggaaagctg gatagcaaaa gacggttagt caaattactt aagcgtgatg ccaaggtctt
    26401 cgatgcagta gaagtaaaag aacaagaatt gcgccagtat ttccaaaagt ggagtcagaa
    26461 acaaggtctg cagtttacca atcattcttt tgaaaatctc ctcatcaagt cggggtttca
    26521 atttagcgaa atccagaaaa atcttctctt tttacagtcc tataaggcga attctgttat
    26581 cgaggaagag gatattgtta acgcaattcc caagaccttg caggacaata tttttgattt
    26641 aactcagttt attctgacta aaaagatgga tcaggcgcgc gatttggtga gagacttgac
    26701 cttgcaaggg gaagatgaaa tcaaactgat tgcagtcatg ctgggacaat ttcggacttt
    26761 tactcaggtg aagattttgg cggagtctgg ccaaacagaa tcgcagattg caagtagttt
    26821 aggtagttat ctgggacgta acccaaatcc ttatcaaatc aagtttgcat taagagattc
    26881 gagaggactt tctttgagct ttctgaagca agctatttcc tatttgattg agacagacta
    26941 tcagattaag acaggtcttt atgaaaaagg tttccttttt gaaaaggcac tcttacagat
    27001 tgctagtcag gtcaattgac atttgttgaa actacaaccc acgtcaggat tatcttgtcg
    27061 tgggtttctt gctgatttgc ttattttatt agaaagtatg tcagtgattt ccttatctat
    27121 aagcaaaaaa cttgaaaaaa gtgaatgttt gcgttatcat tttcatatag aaagaaaaag
    27181 aggtattaca gatggctatt atcttaccag aacttccata tgcatacgac gctttggaac
    27241 catacatcga tgcggaaaca atgcatttgc accatgacaa acaccatcaa acttatgtca
    27301 acaatgccaa tgcagcttta gaaaaacacc ctgaaatcgg tgaagacctt gaagccttgc
    27361 ttgctgatgt agaatctatc ccagctgata tccgtcaagc acttatcaac aatggtggcg
    27421 gacacttgaa ccacgctctt ttctgggaat tgatgactcc cgagaaaaca gctccttcag
    27481 cagaactgac agcagcaatc gatgcaacat ttggttcatt tgaagaattc caagcagcct
    27541 tcactgcagc agcaacaact cgttttggtt caggttgggc atggttggtt gtcaacaaag
    27601 aagggaaact tgaagtgact tcaacagcaa accaagacac accaatctca gaaggtaaaa
    27661 aaccaatctt gggcttggac gtttgggaac atgcttacta cgtgaaatac cgcaacgtgc
    27721 gtcctgacta tatcaaagct ttcttttcag taatcaactg gaataaagta gatgaattgt
    27781 acgcagctgc taaataatga tagttggagg gaagaattgt tcttctcttt tttaggttat
    27841 aagattctgg tctgacaaaa tcgtcagact tttttcattt ttatgagaaa cgtgctaact
    27901 gctagaaatt atggtagaat aaagtattaa gtaatcgtgg aaaaaggata tctatgcgaa
    27961 aagaaattgc acctgaatta tacaactata acaagtttcc tggtccggag ttccatttac
    28021 acggggacaa ggtcgaaacg gaagggatag ctttttcctt ggttgaaaat atcaaggatg
    28081 cctttgatgt gacgactttt aatcagcgtt tttcagaagt attaaccaag tttgattata
    28141 tcgtggggga ctggagcaac gaacagcttc gcctacgagg tttttacaag gatgaccgaa
    28201 cagaagaaaa acttgaaaaa atcagtcgtt tacaagacta ccttttagag tattgtagtt
    28261 atggttgtgc ctattttgtc ttagaaaatg aagcccctaa gcgagcatca tttgacaaga
    28321 aaatgcgtaa gacggaagaa gaaacacctt ctagaaaagg aaagaaaccg actcaaacta
    28381 aacgaaagtc gaatgcagat aagaaaaata gacgtcgtca gaaagaccaa cattctcaga
    28441 aagaggacaa ggaacaacgt cattttgtca ttcgtcagaa gtgagtagag aataaggaga
    28501 agaaatgaaa ccctcaattc atagtttggc acatcaaacc atgcaggaat gggtattgga
    28561 gcagggagaa aagaaattcc gtgcagatca aatctgggaa tggctctacc gtaaacgtgt
    28621 gcagtcattt gaagaaatga ccaacctttc caaggatttg attgctaagc tcaatgacca
    28681 gtttgtggtc aatcccttga aacaacgtat tgtgcaagag tctgctgatg gtacagtcaa
    28741 atatctcttt gaattgcccg acggtatgtt aattgagact gtactcatgc gtcaacacta
    28801 tggtttatct gtctgtgtga ccactcaggt cagctgtaat atcggttgta ccttctgtgc
    28861 ctctggtttg attaagaagc agcgtgacct caataacggt gaaatcgtag cgcaaatcat
    28921 gctggttcag aaatactttg ctgatgaagg ggttcaggtc aatcttgccg tgtctcttca
    28981 cgcacccaac aatgaacttc gttcaagtat catgaaaatt aaccgtgcct ttccgattga
    29041 aaaactcttt gctgctattg aatactacat tgagacaaca aaccgtcgtg taacctttga
    29101 atatatcatg cttaatgaag tcaacgacgg tgtagaacaa gccttggaat tggctgaatt
    29161 gctcaagaac atcaagaaat tgtcttatgt aaacttgatt ccttataacc cagttagtga
    29221 gcatgaccaa tatagccgta gtcccaaaga gcgcgtgttg gctttctatg atacgcttaa
    29281 gaaaaaaggg ggcaactgtg tggttcgtca agagcatggt acagatattg acgcagcttg
    29341 tggacaattg cgctttaaca caatgaaacg tgaccgccag aaggcagtcg cagcggtaaa
    29401 tccttaatga tgaagaagac ttataatcat attttggtct ggggagtcat tttctatagc
    29461 atttgcattg tctatttttg ctttactcct caagaacaat ctaccgtggg agtgggaact
    29521 ccagatattc agcctcttgg acgcctggtt tttcttttga ctcctttcaa ttctctctgg
    29581 aaactgggcg aagtgagtga cattggacaa ttatgttgga tttttttaca aaatatcctc
    29641 aatgtcttct tgttttttcc tctgattttc caactccttt atctatttcc aaatttgcgg
    29701 aaaacaaaaa aggtccttct ttttagtttt cttgtgagtc ttggaatcga gtgtacgcaa
    29761 ttaatcttgg actttttctt tgattttaat cgcgtctttg agattgatga tttgtggacc
    29821 aacactttgg gtggctatct ggcttggctc ctttataaac gattacataa aaacaagata
    29881 aggaattaaa atgagtattt tagaagttaa aaatctgagt cacggttttg gtgaccgtgc
    29941 aatttttgaa gatgtgtcct tccgtctcct caagggagaa catatcggcc tggtcggtgc
    30001 caatggtgaa ggaaaatcaa cctttatgag tatcgtgact ggtaaaatgc tgccagatga
    30061 aggaaaggtt gagtggtcca aatatgtgac ggctggttac ttggatcagc actctgtcct
    30121 tgctgaaaga cagtcggtgc gtgatgttct ccgtacggct tttgatgagc ttttcaaagc
    30181 tgaagctcgt atcaatgacc tctatatgga aatggctgaa gacggtgcgg atgttgatgc
    30241 tctcatggaa gaagtgggag aacttcaaga ccgtctggag agtcgtgatt tctatacctt
    30301 ggatgctaag attgacgaag tagcgcgtgc tcttggtatt atggactttg gcatggatac
    30361 ggatgtaact tctttgtcag gtgggcaaag aaccaaggtg cttttggcaa aacttctcct
    30421 tgaaaagcct gatattttgc tgttggacga gccgaccaac tacttggatg ctgagcatat
    30481 tgattggctc aagcgctatc tccaaaacta tgagaatgcc tttgtcctca tttcgcacga
    30541 tattccattc ctcaatgacg ttattaatat tgtctatcat gtggaaaatc aacagctgac
    30601 gcgttactct ggtgactact accagttcca agaagtttat gctatgaaga aatctcagct
    30661 agaggcagcc tacgaacgcc agcagaaaga gattgcagac ctcaaggact ttgtggctcg
    30721 taataaagcc cgtgttgcaa ctcgtaatat ggctatgtct cgtcaaaaga aattggataa
    30781 gatggatatt atcgaactcc aaagtgagaa accaaaacca tcctttgatt tcaaaccagc
    30841 tcgtacacca gggcgcttta tcttccaagc caagaacttg caaattggtt acgaccgtcc
    30901 tcttactaag cctttaaatc ttaccttcga acgcaatcaa aaggttgcga ttattggtgc
    30961 taatggtatt ggaaaaacaa ctctcttgaa gagtctctta ggcattatct cgccaatcgc
    31021 tggggaagtg gagcgtggag attatttaga acttggttat tttgagcagg aagtagaagg
    31081 cggtaatcgc caaactcctc ttgaagctgt ctggaatgcc tttcctgccc ttaatcaagc
    31141 agaagtccgt gcagcccttg cccgttgtgg tttgacaacc aaacatattg aaagccagat
    31201 tcaagtatta tcagggggag agcaagccaa ggttcgtttc tgtctcttga tgaatcgtga
    31261 aaacaacgtt ttagtgctgg acgagccgac caaccatttg gatgtggatg caaaggatga
    31321 gctcaaacgc gctctcaaag aatatagggg atctatcctt atggtctgcc acgagccaga
    31381 cttttatgaa ggctggatag accaaatatg ggattttaat aatttaactt aagaatgaga
    31441 gtaaaagaaa tacagtaccg aatgtggata ctgtattttt ttggttttta agatttaaaa
    31501 tcgtagtctt tcaccacttc gatgctgtcg attgtgatag cagtagttgg cttgtctttt
    31561 tcatcttttt cggccttagc aatcttatcc acaacatcca taccgtcaat cacttgacca
    31621 aagactgggt gtttgccatc tagactaggg tttccacctt ctttgtaggc ttcgataatt
    31681 ttctgtggat acttgcttgt agggagttta gaagaggtat ctgtagagtt ttggttgatg
    31741 aagaactggc tgccattggt gtttggttga ccagtattag ccatagcaag agcaccacgg
    31801 atgttataca aataaggagt aatctcgttc ttgaaaccag ttcctttgtc tttagtctta
    31861 tccttgtcat gccagatgga ctgaccacct gtaccgtccc cttttggatc tccagtttgg
    31921 accataaagc catcgatgac acggtggaag gtaataccgt tatagtagcc ttctttggcg
    31981 tgagtgagga aattttcaac cgctagagga gcgagtttag ggaagagttt aatgcgaata
    32041 tcaccttggc ttgtgtggag aatcacttcg gcttcatctt cagcaacttc cttagatagt
    32101 tgtgggaaat tggcgttttc gtttgttaaa gcatcgttta actccttggc agattgggca
    32161 gctactttgg aactttcttc agcagcaaga ctggaatcaa cataatcatc accacgcaga
    32221 ctgcgttgga cgctgctaca cccagctagg gctacagtag acagtaaaag aagggttgct
    32281 agttttttca ttctgatcct ctcaaaaatt catttataac cattgtaccc taaaaggaag
    32341 tggatttcaa atattagtag tttacagaac tggcttagat aatagttggg atttcatcat
    32401 catcttgaaa atcttcaact tcttccccag taaatggttt ctgaaaagaa cttagtataa
    32461 aacgggcaat tggttcaaca attaggaaat ttagaggaag agctgcaata aagtttacga
    32521 accaggcgct tagataggta ttgggtgtga tagcaatgcc attgtaaaaa aagtccatag
    32581 aaggacatga aagtgaccag ctaattcttc ttctgaaaaa tgctcatgaa gggcttgatc
    32641 caggtcgcaa gatttcattt tagaaagtcc agtaactccc ttcttcttca ggatattctt
    32701 tttcatggta gtatttagat ggtcaagtga gtcaaaagaa gtttcgacaa gagcataccc
    32761 tttttctacc agagttttta gatgtttagg ggcatcaata ccataagtgt actcaaagta
    32821 ttttggaaac cagatcttaa gaaagctcgt aaagctagcc agttctctaa acgctaagaa
    32881 ctagctacaa cacagcattt acaacacttc atggttcaca ccatggggtg ttttttaatg
    32941 attttaagca aaattcacac ttaattgaaa gttatttaaa ttagatgaaa atttattttt
    33001 tgaaaaagtg ggaaaacatt gattctaagc gaattttgaa tcatattcga atgggagttt
    33061 ttaaaatcat gtttcagtgg taaaagtacc aaactggatt ctccatagta aaatgatatc
    33121 tcctgctagt gaatcatcta ctaataagtc catatttcgc ttgggaacgg gcttgggact
    33181 tagaagccaa gtatccaact ctcgttcagg cgatatgaag ggtttgactt ggtgttcttt
    33241 ataaaatttt tctaaaatag tattcacgga tagcatcttt caaacattta tttcctattc
    33301 taacaaattt ctaaatactt taagaaattt atagtctgtc aagttttttt cttgacacat
    33361 gtcagaaatc tgctataata gaacatgtgc taaatagctc agctatttca ccgaaataaa
    33421 aaattaaaga aatgagactt taaaaatggc agttaaaatc cgtttgactc gtatgggttc
    33481 taagaaaaaa cctttctacc gtatcaacgt agcagattca cgttcaccac gtgacggacg
    33541 tttcatcgaa acagttggaa cttacaaccc acttgttgct gaaaaccaag taactttgaa
    33601 agaagaccgc gttcttgcat ggttggctaa tggagctcaa ccttcagaca cagtacgtaa
    33661 catcctttca aaagaaggcg tattgaaaaa attccacgat tctaaatttt caaaataagt
    33721 ttaaagtagg ttgacagatg gatacgattg aaaatctcat tattgcgatt gtgaaaccct
    33781 taatttcaca accagatgcc ttaactatca agattgagga tacaccagaa tttttggaat
    33841 atcatttgaa tcttgatcaa agcgatgtgg gtcgtgtaat cggtcgtaag ggtcgcacta
    33901 tttctgcgat aagaacgatt gtctactctg tcccaactga atacaaaaaa gtaagaatcg
    33961 ttattgacga aaaataagaa gggcgggacg gatgtctcgc ttttttgtgt ggaatagaag
    34021 atatagtaaa atgaaacaag aacaggacaa atcgatcagg acagtcaaat cgatttctaa
    34081 caatgtttta gaagtaaagg tgtactattc tagtttcaat atactataaa agattgaacg
    34141 tttaggcaat tccaagacta cttaatcgaa cattaacagc agtctcggac tgatgaaggt
    34201 ctctttatga agttagtgga ggaagtcgga aaagtagccg aggttttgaa taggcgctct
    34261 ggtcgaaaag aagggatagg attcgaacga ggaacttgcc agagaactgg ctgatatcat
    34321 ttactacacc gtcgcaatcg tagctattaa tcatattgac cttaccaaga ctgtctttga
    34381 gaaagacaaa accgcagccg ttaattacca acataaacat aatttggaag gattattgaa
    34441 gggaaagtag agatgttgtc cccttcctcc aacttgagaa aatccttgga acgtgataaa
    34501 ataaaggata atgattttta ataattcatt atatagaatg agtggatttc tttatgaaga
    34561 ggtttgaagt atctacagaa attggtagcc tctctgttac ttatcaaaag caaaagaaag
    34621 tgctagtttg tctaaacgga gcaggtttgc taccaagtta tgaaaatttt tcacttatac
    34681 ttgaaaaacc tcctcctaca attggttatt tgacaattga ttttccgaac acaggtagga
    34741 gtccgattca tgaccaagct ggaaaaaatc tagataatct tgcagatgcg gtttatgaag
    34801 tacttgaaga attaggaatt tctgaatata tactttgtgc acatagttgg agtggaattt
    34861 tagcttgcaa attactcgag aaaccaatta agcgtcagac tttagtagca attgaaccga
    34921 caactaaaaa agtcatgttt gctgattttt cagaaaatcc ttatccaaaa atggaagagc
    34981 agatgaggct gattgacgag tgtggtcctg aactttattt taagaactta actcaagcaa
    35041 catttagtcc tgaaacgaat aaaaaaatct gggaattaat gcaagaaaaa ggcttagagt
    35101 tggaaaatca agatccagaa tttcagatat ctggagagat tactgaggaa gattttgaga
    35161 atttgtcgat agaatctcat gtccctgttt ttattttttg tcagacttat agagaaaaag
    35221 agtacagaga atcagaatat tggacttcca atactaaact cattttagga gggaatcacc
    35281 attatttaca atggtcagaa tcggaaaaaa ttgcggctat tattcgagaa ttgtcagaat
    35341 aagatggaaa aaaggagatt acaggagaca agatgaacta ctttaatatt gggaaaatcg
    35401 ttaatacgca gggattacag ggtgagatgc gagtcttgtc tgtgacggat tttgcagaag
    35461 aacggtttaa aaaaggagct gagctggctt tgtttgatga aaaagatcag tttgtccaaa
    35521 cagtgaccat cgctagccac cgtaaacaga agaactttga cattattaaa ttcaaagata
    35581 tgtaccatat caatactatc gaaaagtaca agggatacag tctcaaggtc gctgaggaag
    35641 atttgaatga cctagacgat ggtgaatttt actatcacga gattatcggt ttggaagtct
    35701 atgagggtga tagcttggtt ggaaccatca aggaaatcct gcaaccaggt gctaatgatg
    35761 tctgggtggt caaacgaaaa ggcaaacgtg atttgctttt accttatatc ccaccagtgg
    35821 ttctcaatgt tgatattcca aataaacggg tcgatgtgga aatcttagaa gggttagacg
    35881 atgaagattg atattttaac cctctttcca gagatgtttt ctccactgga gcactcaatc
    35941 gttggaaagg ctcgagaaaa agggctcttg gatatccagt atcataattt tcgagaaaat
    36001 gctgaaaagg cccgtcatgt agatgatgat ccctacggag gcggtcaggg catgttgctc
    36061 agagcacaac ctattttcga ttcctttgat gctattgaaa agaaaaatcc gcgcgttatt
    36121 ctccttgatc ctgctggaaa gcagtttgat caggcttatg ctgaagattt ggctcaagag
    36181 gaagagctaa tctttatctg tgggcactat gagggttatg atgagcgcat taagaccttg
    36241 gtaacagatg agatttccct aggcgactat gtcctcactg gtggagaatt ggcagctatg
    36301 accatgattg atgctacagt tcgcctgatt ccagaagtga ttggcaagga gtctagccac
    36361 caagatgata gtttttcttc aggtctttta gaatatcctc agtacacacg tccctatgat
    36421 tatcgaggca tggtcgtgcc agatgtattg atgagtggcc accatgaaaa gattcgtcag
    36481 tggcgattgt acgagagttt aaagaaaacc tacgagcgca gaccggattt acttgaacat
    36541 tatcaactga cagtagaaga agaaaaaatg ctggcagaaa tcaaagaaaa caaagaataa
    36601 aggagaaacc tatgcaagta atcaaacgta atggcgaaat tgctgaattt aatccagata
    36661 agatttacca agccatcttg aaggcagccc aaactgttta tgttttgaca gatgatttgc
    36721 gtcaaaatct tgctcaagtc actaagaagg tagttttgga tttacaagaa gccaaggtgg
    36781 aacgtgcgac tatcagtatg attcaatcta tggttgaaca tcgtttattg ggcgcaggtt
    36841 acattaccat tgcagaacac tacatttcct atcgtttaca acgtgacttg gaaagaagtg
    36901 gttatggaga tcatatcgca gttcatttac attttgaaca aattcgctaa gaaaaaagag
    36961 tgggatgaag caactacatc tcactctttc ttaaatctat ttttttgggc tgtttggaca
    37021 gttgagggga caaatcgcag gcgttgaata tcgcttatac ggataatccg gctcacattt
    37081 ttggcaaaat ttttcacgat aatttgctgg ccttgctgat catatttgat gatatcacct
    37141 gtaaagcttg tctcagacaa gataaggtga acagcggttt gtttctggat agcctcttca
    37201 atagtggctg taagggagtt ggtttcagtc tggtcaggtt ggtcatgtcc atttaaaaaa
    37261 tcatgtattt tatctagaac ttgctggaat ttatgtctca tattggcctc ccttcttcta
    37321 tatcaatatt atataaaatt ttcctaaaat ctacaagatt ttacgaataa actaatgaaa
    37381 ctaaaaaagg agaagaaaat ggcagaattt acatttgaaa tcgaagagca cttgttgact
    37441 ctttctgaaa acgaaaaagg ttggaccaag gaaattaacc gtgtgagctt taatggtgcc
    37501 cctgcaaagt ttgatattcg tgcttggagt ccagaccata ctaaaatggg caaagggatt
    37561 actctctcaa atgaagaatt tcaaacgatg gtggatgcct ttaaaggcaa ctaatactct
    37621 tcgaaaatct cttcaaaccg catcagcttt gccttgccgt atgtatggtt actgacttcg
    37681 tcagtttcat ccacaacctc aaaacagtgt tttgagcagc ctgcggctag cttcctagtt
    37741 tgctctttga ttttcattga gtataagttt tcaaaataaa aaaaaaggat attgagtcat
    37801 gataactcga tatccttttt tagttagtaa agtaagcctg atttttaagg cgttgaagta
    37861 ggggacggct aataaaacta atagccagaa gtttgccaag gtctggaatg ataaagggaa
    37921 gaacccccac aacaagagct ttttcaaatg ccattccagc taggaaatgc aagctgagaa
    37981 tcccgccgac aaagacaagg gcatcaccca agaggtttgc aagaaaaatc ttaacaacac
    38041 cactcttgct gttggttaga gaggaagtaa gtccagagta aacgagataa aaccaaagat
    38101 agcctgcagt agggccaact aaagcctgaa aaccagctcc acctcctgca aagacaggaa
    38161 gaccgatagc acctagaaga agatagagtc cagcagaaag tacagcctct ctcggtctaa
    38221 agacagtagc aatcaagccg attgcaaagt tttgcagagt gaagggaaca ggtccaattg
    38281 gaagactgat ttgtgccaaa acagcaatga gagcagcccc aatagcaggg atagcataaa
    38341 cgtgagcttt tttcaaaata gttaacctct tttctaatgt atagtaacta ttatactcat
    38401 ataggagtcg atgtcaacca ttttttaaaa acaaggtaac aaaaactgta acagccgatt
    38461 ttcgtgacta gtcaagttgg ataatttttt tgttgattcg aaaattgtct gt
//
LOCUS       DAVLAQ010000015        36921 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000015 DAVLAQ010000000
VERSION     DAVLAQ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.015"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..1570)
                     /locus_tag="VXB71_000762"
     CDS             complement(<1..1570)
                     /locus_tag="VXB71_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEV0450906.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYDEDQKKTEEKAKKAEEAAKEVDDASLA
                     VQKAYVEQRKAQEEKNKHSGNPEYAKKLAEADKKITEETTKLTDAQTKFQSVQAMVVP
                     EPEQLAETKKKAEEAKAEEKVAKRKYDYATLKVVLAKKEVEAKELEIEKLQYEISTLE
                     QEVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAELNAKQAELAKKQTELEKLL
                     DSLDPEGKTQDELDKEAEEAELDKKADELQNKVADLEKEISNLEILLGGADPEDDTAA
                     LQNKLATKKAELAKKQTELEKLLDSLDPEGKTQDELDKEAAEAELDKKVEALQNKVAD
                     LEKEISNLEILLGGADSEDDTAALQNKLATKKAELEKTQKELDAALNELGPDGDEEET
                     PAPAPQPEQPAPAPAPKPEQPAPAPAPKPEQPAPAPAPKPEQPAPAPKTGWKQENGMW
                     YFYNTDGSMATGWLQ"
     gene            complement(1856..2359)
                     /locus_tag="VXB71_000763"
     CDS             complement(1856..2359)
                     /locus_tag="VXB71_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450907.1"
                     /translation="MKLLDCILDYQERFNRKACQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFIGDIFYFKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            complement(3494..4222)
                     /locus_tag="VXB71_000764"
     CDS             complement(3494..4222)
                     /locus_tag="VXB71_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450908.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            complement(4219..4551)
                     /locus_tag="VXB71_000765"
     CDS             complement(4219..4551)
                     /locus_tag="VXB71_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0450909.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(4607..5509)
                     /locus_tag="VXB71_000766"
     CDS             complement(4607..5509)
                     /locus_tag="VXB71_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450910.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(5515..5832)
                     /locus_tag="VXB71_000767"
     CDS             complement(5515..5832)
                     /locus_tag="VXB71_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450911.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGDWNTFKNNIKGLARASSGFRF
                     AARETGLWAAIWSTRVYSYTYVVSAFAPILGSVAAVNAALAVIGGISVAGITYALWTR
                     KFY"
     gene            complement(5977..7329)
                     /locus_tag="VXB71_000768"
     CDS             complement(5977..7329)
                     /locus_tag="VXB71_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV0450912.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADNKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLLPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(7326..7793)
                     /locus_tag="VXB71_000769"
     CDS             complement(7326..7793)
                     /locus_tag="VXB71_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0450913.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(7786..10005)
                     /locus_tag="VXB71_000770"
     CDS             complement(7786..10005)
                     /locus_tag="VXB71_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0450914.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            10471..11334
                     /locus_tag="VXB71_000771"
     CDS             10471..11334
                     /locus_tag="VXB71_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0450915.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(11623..13014)
                     /gene="argH"
                     /locus_tag="VXB71_000772"
     CDS             complement(11623..13014)
                     /gene="argH"
                     /locus_tag="VXB71_000772"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0450916.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(13043..14240)
                     /locus_tag="VXB71_000773"
                     /pseudo
     CDS             complement(13043..14240)
                     /locus_tag="VXB71_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(14257..15063)
                     /locus_tag="VXB71_000774"
     CDS             complement(14257..15063)
                     /locus_tag="VXB71_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0450917.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLVTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYSVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(15270..15911)
                     /locus_tag="VXB71_000775"
     CDS             complement(15270..15911)
                     /locus_tag="VXB71_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450918.1"
                     /translation="MIELENITKTIGGKVILDRLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(15908..18016)
                     /locus_tag="VXB71_000776"
     CDS             complement(15908..18016)
                     /locus_tag="VXB71_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0450919.1"
                     /translation="MKKISHLCMLLLLLCTTFFVLNVNVTREIVRIQEMGKTTYSFDL
                     YLKDVTKPTETILQFFEEVASQDKVSIIKVDNGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLFSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     ALASRMEKRSLVELLKGGIL"
     gene            complement(18071..18364)
                     /locus_tag="VXB71_000777"
     CDS             complement(18071..18364)
                     /locus_tag="VXB71_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0450920.1"
                     /translation="MIGEINHEKISVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            18770..19090
                     /locus_tag="VXB71_000778"
     CDS             18770..19090
                     /locus_tag="VXB71_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0450921.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(19142..19729)
                     /locus_tag="VXB71_000779"
     CDS             complement(19142..19729)
                     /locus_tag="VXB71_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0450922.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            19971..20642
                     /gene="sdaAB"
                     /locus_tag="VXB71_000780"
     CDS             19971..20642
                     /gene="sdaAB"
                     /locus_tag="VXB71_000780"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0450923.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20651..21523
                     /gene="sdaAA"
                     /locus_tag="VXB71_000781"
     CDS             20651..21523
                     /gene="sdaAA"
                     /locus_tag="VXB71_000781"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0450924.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            21545..22177
                     /locus_tag="VXB71_000782"
     CDS             21545..22177
                     /locus_tag="VXB71_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0450925.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            22203..22301
                     /locus_tag="VXB71_000783"
                     /pseudo
     CDS             22203..22301
                     /locus_tag="VXB71_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(22483..24333)
                     /locus_tag="VXB71_000784"
     CDS             complement(22483..24333)
                     /locus_tag="VXB71_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0450926.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(24375..25532)
                     /locus_tag="VXB71_000785"
     CDS             complement(24375..25532)
                     /locus_tag="VXB71_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0450927.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            25590..26756
                     /locus_tag="VXB71_000786"
     CDS             25590..26756
                     /locus_tag="VXB71_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0450928.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            26895..27221
                     /locus_tag="VXB71_000787"
     CDS             26895..27221
                     /locus_tag="VXB71_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0450929.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            27208..27801
                     /locus_tag="VXB71_000788"
     CDS             27208..27801
                     /locus_tag="VXB71_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0450930.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            27794..28705
                     /locus_tag="VXB71_000789"
     CDS             27794..28705
                     /locus_tag="VXB71_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0450931.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            28768..29832
                     /locus_tag="VXB71_000790"
     CDS             28768..29832
                     /locus_tag="VXB71_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450932.1"
                     /translation="MKQEWFESNNFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(29904..30764)
                     /locus_tag="VXB71_000791"
     CDS             complement(29904..30764)
                     /locus_tag="VXB71_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0450933.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDDSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLAQEK"
     gene            complement(30886..31872)
                     /locus_tag="VXB71_000792"
     CDS             complement(30886..31872)
                     /locus_tag="VXB71_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0450934.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(32144..33619)
                     /locus_tag="VXB71_000793"
     CDS             complement(32144..33619)
                     /locus_tag="VXB71_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0450935.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(33877..34800)
                     /locus_tag="VXB71_000794"
     CDS             complement(33877..34800)
                     /locus_tag="VXB71_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0450936.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(34814..35743)
                     /locus_tag="VXB71_000795"
     CDS             complement(34814..35743)
                     /locus_tag="VXB71_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0450937.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(36062..36283)
                     /locus_tag="VXB71_000796"
     CDS             complement(36062..36283)
                     /locus_tag="VXB71_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450938.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(36237..36497)
                     /locus_tag="VXB71_000797"
     CDS             complement(36237..36497)
                     /locus_tag="VXB71_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450939.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT        11305 a         7770 c         6239 g        11607 t
ORIGIN      
        1 tttggagcca tcctgtcgcc attgaaccat cagtattgta gaagtaccac ataccgtttt
       61 cttgtttcca gcctgttttt ggtgcgggag ctggttgctc tggttttggt gcaggagctg
      121 gagctggttg ctctggtttt ggtgcaggag ctggagctgg ttgctctggt tttggtgcag
      181 gagctggagc tggttgctct ggttgaggag ccggcgctgg agtttcttct tcatctccat
      241 cagggcctaa ctcattaaga gctgcatcta attctttttg agttttttcc aattcagctt
      301 ttttagtagc taatttattt tgaagagcag cagtatcatc ttcagaatca gcccctccaa
      361 gtaatatttc aaggttacta atttcttttt ctaaatcagc aactttgttt tgaagagctt
      421 caactttttt atccaactca gcttcagcag cttctttatc taattcatcc tgagtcttac
      481 cttcaggatc aaggctgtca agaagttttt caagttctgt ttgttttttt gctaactcag
      541 cttttttagt agctaattta ttttgaagag cagcagtatc atcttcagga tcagcccctc
      601 caagtaatat ttcaaggtta ctaatttctt tttctaaatc agcaacttta ttttgaagtt
      661 catcagcttt tttatccaac tcagcttctt ctgcttcttt atctaattca tcctgagtct
      721 taccttcagg atcaaggctg tcaagaagtt tttcaagttc tgtttgtttt tttgctaact
      781 cagcttgttt agcgtttagc tcagcttctc ctttttttaa tttagcttct ataacttctg
      841 tgccatcatc aggatccgca ccagcaagaa gttttttcaa attatctact tgatgttgag
      901 cagtagcaac ttcttgttcc aaagtagaaa tttcatattg aagtttttca atttcaagtt
      961 ccttagcctc tacttctttc ttcgctagta ctacctttag agttgcataa tcatattttc
     1021 tcttagctac tttttcttct gctttagctt cttctgcttt tttcttagtc tcagccaact
     1081 gctctggctc aggaactacc attgcttgaa cagattgaaa ttttgtctga gcatcggtta
     1141 gtttagtcgt ctcctcagtt atttttttat ctgcttctgc taatttttta gcgtactctg
     1201 gatttcctga atgtttattt ttttcttctt gtgcttttct ttgttccaca taagcttttt
     1261 gcaccgctaa actagcatca tctacttcct tagcagcttc ttctgctttt ttcgctttct
     1321 cttcagtttt cttctgatcc tcatcatatt tcttctgagc gtcttctgct ttctttttag
     1381 ccgtttcgta atctttcttg gcagtatcag cttttgcttt tgcttcctca tatttcttct
     1441 ctaatgaaga tttttcgaca acttgtggag cttcttctgc tcttacaaaa gtaggctgag
     1501 acgtaacaaa accagcccct aagatagcga cgctggctag acttgttaaa atcatttttt
     1561 tcttattcat ctaaatttac ctcttttctg atagtcattt ttagactata cttatattaa
     1621 gtatactccc cccgtaaata tttgtcaaat gttttatatt acatttttat tacaaatttc
     1681 tatatcataa gcttctactc caaaaagata aagacactac ttttgccctt ttcgattctc
     1741 tttttaaaca tagcatcatc ttccttcatt cctataaaaa catttccgat gagagagctt
     1801 gttttttaat ttcgttaaac aacaaaaaac gcaagcttaa gcctgcggac aatctttata
     1861 gccatttcat ttctttcaca tctgttttac gaactttagc atatttctta gcgcttgtaa
     1921 aatgtagagt aactggttta aatactccgc ttttgtctct tcgtaaacct aaaactgcgg
     1981 atcttttatt tttatcctca aaaaatatga cgtccaattt catagtattt ttagataaat
     2041 ccttagctac gatgcaacaa cttgttattt taaaatagaa aatatcacct ataaactcat
     2101 ataaagatat cctttcgatt acatcattgt acaataggat atttctaaaa tcttctaaaa
     2161 taaaaacacc agcttgaata gcaggttttg tttgactagc ataatctcgt gtgattttgt
     2221 gtaagccaaa taaatgatgt aaatcagtca ggcaaaaatt cactttgaaa gtctctaaat
     2281 acttataatt cgttgatact tgacatgctt ttctattgaa tctttcttga taatccaaaa
     2341 tacaatcaag taatttcaac gacaaactcc atattttctc aaaataaaaa agcacggggc
     2401 agttctcact actgcccaaa gtggttgatt agagtcggct tctctaactc cctatgttgt
     2461 gcttattagg cttatcgcaa gggaacagtt tttagctctg ccaagccaca tagtgtgctt
     2521 actactatgt gtccatgtca ccatgaattg ccgaacggtt taacgagaaa gtatagtaga
     2581 ttgaaacaag atgtgaacaa atcgattagg aaagtcaaat taatttctag aaatatttta
     2641 acagtcataa cggactattc cagattcaat ctactatatt acttttaggt ttatcccaac
     2701 tcaattatga catctttttt tcaaaagtca atatatctca ctcttttcaa cgacaagaaa
     2761 gaggctgata atcgaccaac ctctgttttt agatacagtt caagtccaaa ctattcttta
     2821 tagaaaagtc cgataaattc gagcaatagt taacatactt acaaatataa ctcccaaaat
     2881 agataacact attttcacaa aactcagttc cgaacctatg acatatatat gaaaaagagg
     2941 ggctagtcct acacatatat acaataagta gccaacaagt tttatctcac caattcctgc
     3001 aaaaaaatgt ttcatgtaac gattctccat ttactctatt aaatcaattt tattttagac
     3061 tatcataaca caatcacctc ttcaataaaa accattggcg aaatactatt ctgaagcatt
     3121 gatagctcag atttctcaga atagagctgt cctaactatc gagcagctca aatacatata
     3181 tatgagcaat tctaagttta gaattgctat aaaataaatg tttccaggct attctaagtc
     3241 tttgactgct taaaatttta cgttctgaag gattctaaag ctagaacagc tcaaaatcac
     3301 gagaactaag gtattcgaaa cttcagagta atacaatccc cataggaatt ctccattctt
     3361 attaagcatg attaaaatgt aatcctaaca agtgatcctc gactgtgttt gtagcactta
     3421 gttacctaga taagactatt tccctttatc atatctgatt ttaagccgtt ctaagattta
     3481 acctatgttt ctattacttg ctatttttaa ataattcgaa ttccttttct ttgataaatg
     3541 gaactgaaaa attagaaaaa agaagtaaaa ccgaaaacaa atagcctgct ttttgaatca
     3601 ctaaaagata tcctaaaaat aagtaaacta taacatccaa tgcgaaaaga aaaaatattc
     3661 tcctcttcat taaagtactt gtgtcaaata atctgatgaa taaaaatttt atcgtagtat
     3721 ctacacaaat ttttatcaaa aagataagag ccaatacacg attatcaact gtaccgtaaa
     3781 gaatagatgg aaatatagtt aatataaaac tagaaatctc taaatatttt atccaaggag
     3841 attgagacac cttgcttcta aactgactaa ttttcttata ttcgttagtc aatttagtag
     3901 caaaatcttc cccaattaaa tgaaagattg ctaactctag gataaaaaca cttattaata
     3961 cggtataagt caaaaaactt tctgggaaaa acttattgat taaaatgggg aaactcatta
     4021 acagaatcga atttatggct agacagatag atactatttt atttttcaca gaatatagag
     4081 gtagtgatac tattgagtag ataaaagcta aaaaaataag caaaaaatac tccgtgtcat
     4141 ttataatcgc cctgaatgat aaaaatatat acatccaaca tacgataata tgtatttttc
     4201 gaatcttatc tacattattc atcttactgt cgcagatata aatccatccc aaggataagg
     4261 gttcccgcta atatcacaac ctctattaag agcaccatat ccaatacagt aagctatttt
     4321 tcctgctgct gcaccaataa gccagcctcc aagacctcca accttaatat agtttattag
     4381 ttttttggtt aaaactgcag ctccagctaa tgctataaaa gttcctgaac tcatagctaa
     4441 agctacgcaa attccttgac aagcacgctt gcttaaataa gctcccccat caagatacat
     4501 catttcttct tcatcaatca caacataatt atttggtaat acaagttcca tttgttttct
     4561 cctccttagt tgaaattgtt tcatttgttt tacaaatagg acgaacttaa actatctttt
     4621 tattactcag taataatttc cgagatttca ttttatgata ctctctattc atacagaaat
     4681 caaaattttg ccttaaccaa cttgtataat agaaaaaatc taattgattt attctgatga
     4741 gctgtattct aattttatca accttttctt gccagttgtt attgttacta atagaaatct
     4801 catacagcag taactcgaca agacctgtac acagaagggt gttatgagaa tcttcaattt
     4861 tactcagaat atcctcaaaa agttcactat ccgttaaaaa ggtggattga ttcatcgcat
     4921 catacagctg aagagacatt aagtcagaat aactgagatc tgatttttgt attttatcct
     4981 ttaacgtatt tgtcaaatca ctttcaaacg aatcttcttt ttcccattta ttttgattga
     5041 aaagaaattc cgtcttatta aaaacgagat gattgatatc cattatagtc caaaaaaata
     5101 ttgtagtaag cataatgatg acaaaaggaa tttttaaaat aaatactagg ataatagcaa
     5161 tttcaagaat aaaactccat ataatcctag atcttaaatc atcaggcgac aaacttttac
     5221 gatggaatga aaaatagggc gagaacctca catttacttt cttcctgcct ataaaaataa
     5281 aaggaaaaat cgtaataaga gcttctttct tgtacaaatc tttcaatgcg tatagtatgt
     5341 ctaaaactat ttttgataaa atcaaactac agaaagcaag actcatacta atcacaaaat
     5401 caaggggaga ttctagattc aatagtaagt tattcactag gacatgcaac tctagccaca
     5461 agacaaaaag agggagcatt agtaagaaaa caattagttt acgcattata acaattagta
     5521 aaatttacgc gtccataaag catacgtaat tcctgcaact gaaatacctc caattacagc
     5581 caatgccgca ttaacagctg ctactgaccc tagtattgga gcgaaagcag aaacaacata
     5641 agtataagaa tacactcttg tagaccatat tgcagcccat aaaccagttt ctcttgcggc
     5701 aaacctaaat cctgaggaag ctctcgctaa accttttata ttatttttaa atgtgttcca
     5761 gtctccccca tcaaggtaca tcatctcttc ttcatcaatc acaacataat tatttggtaa
     5821 tacaagttcc atttgttttc tcctttttat taagcatggt taggatggtt tcctaacaag
     5881 taatcgtcgt ctgtgtttct atcacttagc tacctagata agatatcctt tctctacctt
     5941 atttgttttt ataggttacc taaggtttaa aaccaattat tgcttgaaac ttaacatttc
     6001 taaaatccaa tcaagatagg tttctttatc atagacaatc cgcacttcaa ctggcatatc
     6061 cttttggagg acgactgtct cacttccatg ttttagagtt aaggtttcta attctatcat
     6121 gactttataa agactaatat tgccttcttt cgtttcttgg gaaattgttc ctgaatcaat
     6181 ctgtctgact tgtcccttta gtgttccata tttttgacta tttacaccag taatagcaac
     6241 atcagctttt gctcctttcg aaacacgaga aatatcactc gcaagtacaa aagcttctac
     6301 atagtaacct ttttctttcc ctgaaacttc tgctatcgtt tgcccctgct gaatagacat
     6361 tccttgtttc aaaggtaaca gataatgcag agtaccttca tttggcgcta atatactatg
     6421 agctttatct tgacctgttg ccactccaag attagcctca agctctgtaa tacttttatt
     6481 gttgtttgaa cgagcagtac ctaactcact aactaattga gcataaatat tataagcctg
     6541 agaagttgga tcattatagg tacggttcat atccttaata ttgctttgtt gactatcaat
     6601 ctcgctattc ttagaagtaa tatttgtttt taatgcttcg atttttgttg ttatttctga
     6661 tatcttagtt tctaacttag ctttgttatc agctgatgtc gtatctgata gagaaggtga
     6721 gtctccttgc tgttgaagtt gaagcaattc attttgtaga gcttgcaagt cggcatctaa
     6781 ctgatttctt tcagctgtta ttttattcaa cttcgtatat tcatcctgaa tctttgaata
     6841 ctgggtacca ttattataat tttccgaatt taactgagat aggtagtatt caactttccc
     6901 ataatattcc tgttcttcac cagaattaga taaatgattg tatttctcat ttaatgattg
     6961 ttcaaatttt tgaaagatag cttcttttgc acgtaacttc tccaattgtt tatttaaaga
     7021 gctcgcttgt aaaccttctt gcccacttga taacgaaata atgacatctc cagcatttac
     7081 catatctcct tctgacttat gtaaagtaac taccttccct gaaccaattg ctgataggaa
     7141 ctctgtacct gttataactg aatttccatt cgcttttaca atatagtttt tgggtatata
     7201 agctgcgcca accaatgcac cgcttaagat aatagcagtt gaaataatga gaataaacgc
     7261 aaaagctggt ggtctcttat caaagaaaat acgagaataa cgtaattctg atttattata
     7321 taatttcata ggcttacaat tggtctaaaa atatctacta ccattttttc aggagaagaa
     7381 ttaacataaa ctgtatagac aatcccatcc gtttgaatat cattttcata gacatataga
     7441 tccaatttag aatacgcata ctgtagatac tctggactgt cttcaaaacg aacatataaa
     7501 caatatggaa cagagataga atcctgtaca tcataaatgt tactgtactg ttgagcatta
     7561 tgagcttgaa tataaaactc aaaatcagtc gttattaatc catcatcatg aatagtagta
     7621 ccacaacttt ttacaattaa tggaccaaaa atttgtgctt ttaacaactg caaatgttga
     7681 tgaaatttat taatttcctg atctacatct tctacttttg tatcatgtaa ctttttacag
     7741 ataactgact ttagtaccag ttttttatta tcttttacct ctaacttagc cataagtaac
     7801 ctcctctgta tctaacacag cctgtgactg aatttgttga ttcacttgaa cgctctgcaa
     7861 accaaccatt ctagcatact ttccattttt cgccattagt tcttcatgag taccatattc
     7921 cataatagtc ccattttcta aaaagcatat cttatcacat cgaagaattg tagacagcct
     7981 gtgggctact acaattgttg tcttatccat tattttatta aagattaaat cctgaataat
     8041 ctgttcacta aatgaatcta agttagaggt tgcctcatca aatatataca aatcagcttt
     8101 actcagtagt gctcttgcaa tagccaatcg ttgtttctct ccacccgaga aattttgacc
     8161 gccttcttct acaaaggagc cataacgatt ttgaagacgt tgaatcgtat catgaatacc
     8221 aacaatacga caaactctca ccatatcctc atatgtaaca gaaggattac caatttttag
     8281 attatcaata attgtccctg taaagagttc tatggtctga ggaatgtagg aaattttctt
     8341 acgtagttta ccatagtcaa gatctgataa gtcattttct cctatacgaa ttttcccctc
     8401 actcggattt ataaatctta ataacaaacg aactagcgta ctttttcctg ctccgctttc
     8461 tccaacaaaa gctatttttt ctccttgttt aattcgcaaa ttaaagtcct tgataacagg
     8521 agggcgtgaa ccataggcaa atgttacatc tttaaattca atgtcatcac ataaggtgaa
     8581 gtctctaata ctataatcca aggcaatgtc ttcacgatct acttccatca attcttgaag
     8641 ccgactaacc gcaacctgta cctcttgaaa ggttaactgc aagccaacta aattctgaat
     8701 aggttctgta aaatattgac ttaatgtctg aaaaaccaag aggtccccaa tagtcatttt
     8761 tccatcaatg ataaataagg cgcccactcc cataaataat aacccaccca tggttgaggt
     8821 cattgaagat attgtagatt gaatattctg caaaacaccc tctttataac caatttctaa
     8881 agtatgaaca aatttttctt caattttgtt taaacgttgt tcctcatcat gctgagactt
     8941 aatggtatca atgttacgaa tagattcaat taactgtgaa ttaagaagtc catttgcttc
     9001 catttgttca tgattaattt ttttataagg ctttttaaaa cagtatataa gaatgatgtt
     9061 aacaataacc ataaaaacta atatcagaaa taaagattga ttaatagtcc aaaggacaac
     9121 cgcactaata actgacaagg tgatatccat gactaatgaa atagagactg acgtaaacac
     9181 attctttatc gtcatcgcat cttgaaatct tgttaaaaca tcaccaactc tacgacttcc
     9241 aaaaaaacta taaggaagat gaataatatg gtcataatat cccattaaaa ccggtatatc
     9301 aatttttcga gatagaaaca aaagaacgtg ctgacgaaat gcagatagaa gagtctgtaa
     9361 gaacgacact attccaaata ctatcaaaaa catatacaga ctatttttta aagcatatgg
     9421 aatcacctcg tccatgataa cttttgaaaa gagactcgat aaaataccaa tgatacttaa
     9481 aacaaaggaa gctaatatga ctgtactaat caatcctttt tgattaaaaa ttaaccttcc
     9541 aaataaatca agaagtcctt ttccctttag tttccctctt tcaaaatccg aatttggaac
     9601 cataaaaaga gtaatacctt gataaatttc tcccagttcg tcacttgaca tcttgcgtat
     9661 gccactagca gggtctgcta cgtagaactt actattcctt ttgatactat gtagtaccac
     9721 aaaatgattt tgacctaaat cattcttaac ttgaagaatc gcaggaaatg ttaattttgg
     9781 agtcaaatct tccagtgcta ctcgaacagc ttttactgta aaattcaact tattcagacc
     9841 tgaaacaata ccactgacag tcgttccata catgtctgta ccaataattt ccctaatctt
     9901 catgattgat agttcctttt tgtaagataa aagaactgtt gaaacaactg ccgcagcaca
     9961 atctgactgg tcatgttgca tcgtacaagg atattttttt aacatagaaa tactcaattc
    10021 tttagaatta atctaacttt tctttgatgt cacccaaacc tcaatcactg cccagtagtt
    10081 cttgaattaa tttattttca accgtatcat tctttgttct tgatatcttt ccaagcattg
    10141 tagtacagca gatttttgcc caaggactga gcctccttta acaactcaaa ctcccttaca
    10201 ttatatcggc cagccccatg gaaagattat agccagacta atcaatgata taatacatac
    10261 tagaatacaa aatatttttt tattcatact ttttctccta tctttatttt ctacctacat
    10321 agtacctctt attaagctca ttttaaaatt acgttaactt ttttcacaaa tttatttcga
    10381 ctttcttttt tactttttac attgctatga tacaatattt ttaacaaaat tttattgttt
    10441 gttaactttt ttcacgaaaa ggagaaaatc atgcgttatg atttcggaaa ggtctataaa
    10501 gaaatacgtg agtcaaaggg gctgacccaa gaagaggtct gtgggggtgt tctctcaaga
    10561 accagcttat caaaaatcga aagtggcaag acaaccccaa aatatgaaaa tatggaattt
    10621 cttctccgtc aaatcaatat gagttttgaa gagtttgaat atatctgtca actttatcaa
    10681 ccaagtcaac gcacagagat tatgcaaacc tatctcaata tgcgttccat tatcgggacc
    10741 agcgatcttg tcaatttatt tcaaaaatgc caagactacc tcaagaccca ccacgatctc
    10801 cctatagaag aaatcagaga tatgcttgaa gttgttattt atctccgtca acacggggca
    10861 ggggaactat caaaacacgc agaacaggtt gtcaaaaaac tttggaaaaa aattgaaaaa
    10921 caagatacat ggtatgagag tgatctaaaa atcctcaata ccattctttt cagttttccc
    10981 attgaatacc tccatctcat cactggaaaa atattgcaac gcctagaagt ctataaaaac
    11041 tatcaacatt tatatgactt gcgaatgaca attctattaa acctttccac actctatcta
    11101 tacaatcaag ataaaaacat gtgtaagcaa atctgctaca ctttactgga ggacgccaag
    11161 aataagaaaa gctacgatag gctggctatc tgctatgtcc gtattgggat ttgtagggat
    11221 gatgcgaaac ttatccaaaa agggttctcc cttctggagc taaccgagga aacttctata
    11281 ctgtctcatc tcaaaaaaga agtagagatc tattaccaag cgaaggaaag ataaaaaagc
    11341 cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat accagccatt
    11401 gttaaaccag aagtttttag ctctgccaag ccacatagtg tgtttactac tatgtgtcca
    11461 tgtcaccatg aatcgccgaa cgatttaacg agaaagtatg acttttacgt ttatcccaac
    11521 tcaattatga catttttttc aaaagtcaat atatctcact ttttcaacga caagaaagag
    11581 gctgccaatc gaccaacctc ttattctgaa cccatcactc catcactttt tagcttcatt
    11641 cgctttctta gcgactgcaa tctggtattc gacttggtca aaccctgtgc ctcccaagga
    11701 atttcgtctt tgaacagcag ttttaggttg caagtagaca tagatatcct cggtaatgag
    11761 agaatgatag gtttgtaatt cctccaaagt ccaatcttga agatttttag cagacttgat
    11821 agagtctagc actaatcttc ccacaacctc atgagcttct ctaaatggca agcctttccc
    11881 tgccaaataa tctgccaact cagttgcatt tgaaaagtcc ttctctgttg attcttgcat
    11941 tttttccttg tttacctgca aactagataa catacctgcc aacacatcga gggaatttaa
    12001 aatcgtttcg accgtatcaa acattccttc cttatcttct tgcaaatcct tattataagc
    12061 taaaggcaag gacttcatga ctgtcaacag tccaaacaaa tgcccataaa ctctgccagt
    12121 ctttcctcga atcaactcag ccatatctgg atttttcttt tggggcataa tagaggaacc
    12181 tgttgtaaac gtatctgaca aggtaatgaa ttggtactca aaactacacc aattgatcat
    12241 ttcttcgcaa aaacgactca tatgcatcat gagtatgctg gcatttgata gaaattctaa
    12301 gataaaatcg cggtcactaa cagcatccaa agaatttgta taaggttgct taaactccag
    12361 caaatcgcta gacaattggc gatcaatggg gaaagtcgtt cctgccaaag ctgccgcacc
    12421 taaagggcat aggtctgtat gcttctggtt aaattcaaaa cgttcactgt ctctttgaaa
    12481 catattgtag taagccatca ggtggtaggc aaaactaata ggctgggcat gttgcagatg
    12541 ggtatagccc ggcatgatcg tcgccacatg attttccgcc aagtctaata aaacaccctt
    12601 aagatgagcc agtttatcta ggacatagcc tagttgttcc ttgagataca agtgcatatc
    12661 tgtcgcaact tggtcatttc gagaacgagc cgtatgtaac ttccctgcaa ggggaccaat
    12721 tttttctgtc agcaacactt ccatattcat atgaatatct tcgtttgcga tatcaaagtc
    12781 aagttgacct gcctctagct cttctaaaag ctctttcaag cctacttgaa tcttttctga
    12841 ctcctccaaa ctcaaaatgc ccgtctgacc caacatctga acgtgggcta aagaaccaat
    12901 cacatcaaat ttagctaatt tctggtcaaa agatatactc gcaccaaagc gctctaccca
    12961 gtcttcgaca gtaccttcaa agcgaccacc ccataatttt gtattcttag ccatatcaca
    13021 tccacctctc tatccaatcg tcctatttgg cgcttttttg aacctcagaa tgaaccttgg
    13081 ttggaagtcc ccataactca ataaagccaa cagccgcatc ttggtcaaag gtatctgcac
    13141 tagtatacgt cgccaaattt tcatcgtaaa gagaatttgg tgatttccga gccacgacct
    13201 gagcgctccc ccttatacag tttgactttt gcagtcccat tgacaacttt ttgagtctct
    13261 ttaatataag caatcaaggc ttgtgtagcc gaactaaacc acaaagcatt ataaatgaga
    13321 tttgataatt cattttctat gattggttta aaatgagcca cttctctcac aagcgtcaag
    13381 tcctcaattt ccttatgagc tgtcagcagg gtcactgcac ctggacactc atagatttct
    13441 cttgatttaa tcccaaccaa gcgattttcc acgtggtcaa tccgtccaac cccatgtttt
    13501 ccagctattt cattgagttt ttgaatcaaa tctgccaatt ttaacacttc tccattgagg
    13561 gaaactggaa caccttcact aaactcaatc tcaatgtatt ctggcatatc tggagcttgc
    13621 tctggagaag ttgtgatgcc aaaggcttct tctggagcct gattccatgg attttccaaa
    13681 ataccacact cattggcacg tccccaaaga ttttggtcga cagagtaggg attgtcaagg
    13741 tcagcaggaa caggcacccc atttttcttg gcataataaa tttcttcctc ccgagaccat
    13801 ttccattcac gaactggagc aatcactttt aaattgggat ccaaggctgc aatcgatact
    13861 tcaaaacgta cttggtcatt ccccttaccg gtacaaccat gagcaattgt agtcgctcct
    13921 atctgatgcg ctatttcaac caatttttta gaaatcagag ggcggctcaa ggcagatacc
    13981 aagggatact tttgttcata ataggcatgt gactgatgag ccactagcac ataatctgta
    14041 gcaaattcgt ccttaacatc aatgacataa gattctactg ccccaacctt aagagcctta
    14101 tcatggatga aatctaagtc tttcccttca cccacatcca tacaaactga aacaacatca
    14161 tagtctttct ttaaccaggt aatagcaact gatgtgtcca aaccgccaga ataggccaaa
    14221 attacttttt ctttactcat gttcttttcc ttctttctat ttttcaatgg atgctttaaa
    14281 ggcatcctca atgagtttgt ctaattcccc agactccttc aacttttgaa tagttttatc
    14341 gactgcctct ttcaattcct tactatcttt tttcatggct accgagtagg aatcatcttg
    14401 ctctttttca aaattgaggt ctgcgattgc taaatcagga ttattttcca caaagccctt
    14461 ggcaactggt tcttcaaaga taacggcatc cacttgtcct gattttaaat ctgtgattaa
    14521 attcccattt ttaggcagag atacgaggga agaattttgt agcaaatctt tcgccatcgt
    14581 ctcttgaatc gaacctttct gggctccgac cttcttctgc gctaagtcgt tgacagactg
    14641 ataagtgact aaatcagatt ttttgacaat gagtttattt tttgcagtat agtagggaat
    14701 ggaaaagtca aacaccttgc tccgttcatc tgtcttagaa acacctgata tggcaagatc
    14761 agcttttcct gattgaacac tagccagtac attgtcaaaa ctcatgggag atagttccaa
    14821 ttcgacacct agttctgttg cgatagcctt ggctaattcg atatctgaac ccacaatctg
    14881 atttttccca tcaaccactt tttggtattc aaatggagca aaatctggat tgagggctac
    14941 aaccaatttt cctttggact tgatggcttc aattccagcc gattgattgt tactacaagc
    15001 aaatagtagg gggagcatca ctaaaccaaa catcgtcatc aacaccttct tcatcttatt
    15061 cataacaaag cctcctttat gtttattcct tttgtttgta taaataatac acctatcttc
    15121 atcctttgtc aagcctaaat tgtaattttt ttcaatttaa aacagaaaaa cctaggaaaa
    15181 ttacataaaa atgtcattcc taggcgtatt tatgctattc ctctctggaa aatatgagta
    15241 ttcagtcagt caaaagaagc tgaacgaact cattttccct cgcccaattc aataatccga
    15301 tgacattgtt gggctacata agcatcgtgg gtcacaataa tgactgtttt cccttctcga
    15361 ttcatctcta agagaaactt caagaccaaa tctctatttt caggatccag cgaacctgta
    15421 ggttcatcgg ctaaaatcag ctggctgggt tttaagatgg ctctagcaac tgcaattcgt
    15481 tgttgttcgc caccagacaa ctcggagacc ttttgatgca aagtagctga caaacctact
    15541 ctctctaaaa tctcttccac ctttttgagc ttatctttct tagacaattt tacatatttc
    15601 agcgccagca taagattgta ctcgaccgtt tcatcatcaa tcagggcaaa attttgaaac
    15661 agataagaga tatgttcacg gattattgtt tgcgacttag cagaattgac cgctagattt
    15721 gtctgaccaa aaatctcata ccgtccgcta taatcaccat ctatcaaacc caataaattt
    15781 aacaaggtcg acttcccact accactctta ccaacaatgg caaccaaatc cccctgatca
    15841 atcctgagag acaagcgatc caaaatcact ttccccccaa tggttttggt aatattttcc
    15901 aactcaatca taagatgccc cctttcaata actctactag acttcttttc tccatcctag
    15961 aagccaaggc tagcacaaat agtatatcca aacatgtaaa gcctgcaaac agcaggagtg
    16021 gcaagaacgc atgggcaaag aaaatcaaga ctagaagagg gagactatag cccagcaaga
    16081 gcagaacgag gagaggacgg tagcgatcga ccagtttcca ccccataaac ttcttggtaa
    16141 taatatccct gcgcttcaat aagaaagtta ttactagtaa gaagtaggaa atcatcatgc
    16201 taaagagacc aaacaaagca aaaagtaggt taaaattccg aacagcatct cgataagaat
    16261 ccactttctc ttgttgaatg gcttgaatag atgaaaattt taaataattt ccatctgaca
    16321 atttctcaac taactctgta atctcttttt gatgttgaac cgtattttca attttaatcg
    16381 gattatttaa gccagttgtt gacagggagg ctttctcatc ccacatcata tcagaatcat
    16441 tgaccaagct aataattgga ttggagagat tttcctttcg cttatcacta tatgggaaaa
    16501 atgaccaatc tccttcataa taggcaatct cgacatccat ctcctctatc gttcgttttt
    16561 gctgctcttc atacttcatc gaatgaaagg caattaactt ccccaagagc tgatttttat
    16621 cttcttcacc tttcgtactt gctggcatca aaataacttt tttaatacca gtatctggta
    16681 gcttgaatcc cttgctcttt agaaaattgc gattggcata gtaaacatcc accgtatctg
    16741 ttaactgata ttgctgaatc tgttctgatt ggacaaaatt ttttacagga agactgctac
    16801 tctgcacata gcccgcctgc gttttttcta ctaaatcctg ataaaatcga tagaaataat
    16861 ccaatgcctt ccctgagcct gccaactgct cttgccacaa gttgtcattg agttggaaag
    16921 tttctaaggt cagataattt ccttggctga tccactgttt ctggtaatcc aactctttgt
    16981 tttcttgctc caaacttttt cctaccccaa ctagcaagac tgtcagtaaa atggtagttc
    17041 caattttcat caaataatta aagagtagac caaatttgaa agatgaaaaa cctttcagca
    17101 gagagctgat tgtcattttt tggattaaga ggtaagtcaa ccaactgata aagagataaa
    17161 gctgcaacag caaaaaatga gacaaccaca gcataggaaa caaatctttt ggcttataat
    17221 caagcaagaa aaacacgcct agattgatca caagagcccc acctaggagg aggtaaaggt
    17281 tgccttttac aacatcagct aaaacagccc tatcttgaaa accaagtaat ttttgtaccc
    17341 caactcgttt catctccatc atcggttgat acactgtcac taacacaaga agcaaaatag
    17401 ccaagacaaa aacaatggca gataaaagca aatctcgatt tatgacttcc actgcacttt
    17461 tgtaggtcgg ctctagcaag gtagcctggt ctatcttgaa aaaatcgctc catttctgta
    17521 caatcctatc cttgtccatc tcttgtgtag aagttatcgt atagcgacca tttaaactac
    17581 gagatgtatc cttgatatag gtttgaaaag tcataagctg aataggtttg gcttttagaa
    17641 aggtcggaat cgtaccaagt ttattggaaa tttctttatt actatagact ccttcaccat
    17701 ctgtggtaaa atcaagagaa gaaatcccaa actcttggta ggggaaggta tctttatcaa
    17761 aaacaccaga cttgaccacc tcatcgccat tatctacttt gataatagag accttgtctt
    17821 ggcttgcaac ctcttcaaaa aactggagaa tcgtttctgt cggtttagtg acatctttca
    17881 agtacaagtc aaatgaataa gttgtcttgc ccatctcctg aatccgcact atttctcgtg
    17941 taacatttac attcaggaca aaaaacgtag tacacagcaa gagcaggagc atacaaagat
    18001 gactgatttt tttcatagag atacctcccg tgaagaaact ccctctccaa aaggggaggg
    18061 agaattttaa ttaaaatcca tagaaatatt ccattcccgt tggtgggaat ttgaagattg
    18121 aagcccgagc ccacgcctca gcttctgcac gatccttaga gaatttattt ccatctttaa
    18181 cagttgctgt atgagagcga gtagaatgta aataatcaga ataaccaaaa tttcctgacc
    18241 atcctactcc atagttccat tgaccaccat caacccatac tgccaaaaca cttgtagaag
    18301 caagtatact acataccatt aaagatgcaa cactaatttt ctcatgattt atttctccta
    18361 ttatcgagag ctattccgta gaaacagcta tagtaattta tcaacaagta tcgtagtcca
    18421 ttggactcac cttccttcta tctcatttca tttttaaaca acgaacttac tcttaactag
    18481 gagaatagtt ctcttctgta tcaggtcttt gaacaaccag agtagtatta atcacactct
    18541 aactattact caagaatcag cccaataaac aatatggata gcgctttcaa atttttaaac
    18601 tctatcccat ccttttatct atattatgag cgaaaatata ataactgtca agtaatcgaa
    18661 gtgaatttta taaaaaaaat tacaagccaa atttgcaaag tttacaataa gccgctaggg
    18721 caatcgtcta tcagaatgtc cgtttatttg tcaataatcc gagaaaatct tgcaacgctt
    18781 agaagtctat aaaaactatc aacatttata tgacttgcga atagcaatcc tgctcaacct
    18841 ttccacactc tatctataca atcaagataa aaacatgtgt aagcaaatct gctatacttt
    18901 actggaggac gccaagaata agaaaagcta cgataggctg gctatctgct atgtccgtat
    18961 tgggatttgt acagacgatt ctaaacttat ccaaaaaggg ttctcccttc tggagctaac
    19021 cgaggaaact tctatgctgt ctcatctcaa aaaagaagta gagatctatt accaagcgaa
    19081 ggaaagataa aaaagccgag ggatttcctc gactctttac atattatttg ttcgttagtt
    19141 cttaatacca gccgttgtta agccagaagt ttttagcagc tgtccatgaa ccgtaacgtc
    19201 ctgcaacgta ggcatctgct acacgttctt ggttttcagc tgagtagtca ccgttcaggt
    19261 atgaatctgt taattggtaa cgtccgatat aacgtccatt tgtagctgta tagctaccac
    19321 ctgattcttt ttgagcaatc cattctttgg cttctgcttc agatccgctt acagttgaaa
    19381 caactgtttc acttactact ggagtttctg ctactggagc tgaaacagtt tcatcttgag
    19441 cggctggtgc cgcataagta gctggcgctg gtgttgcaac aggcgctaca gggccatcga
    19501 taaccaactc ttgaccaaca taaatcaaat gaatgttatc aatgtggttg ttttctgcca
    19561 atttttcaac tgttgtgttg tgagtttcag cgatttctga aagtgtatca ccttctttaa
    19621 cagtgtaagt tgatgattct tgagcagata caaatgatgg agcaaatact gcaaacaagg
    19681 cagctactcc tgcaagagtt gctttaatct ttttagttat tgatttcata ttcgaaaatt
    19741 ctccttcttt ctatagttct atcataccct ttaaatatta ccgtttcttg acacttttat
    19801 gtagaaatat tacaaaatta ttttttattt ccctaaataa ggtgtttttt gtcataaaag
    19861 atactatttt tatgctattt gaggtattag aaaggttttc atccacaatt aaagccaagc
    19921 ccctcattct ttgatataat agagataaga atttttataa ggggaaactg atgaaatcac
    19981 ttcgttttca atctgtcttt gatatcatcg gaccagttat gattggccca tctagtagcc
    20041 atactgctgg tgctgttcgt attgggaaga ttgtctcttc catttttgat gatactccga
    20101 cagaagttga attccaactt tttaactcat ttgccaagac ctatcgtggt cacggaacag
    20161 acctagccct tgttgcaggt attttgggaa tggatacaga tgatcctgaa attccaaata
    20221 gtctggaaat tgcccacaag cgtggtatca agattgtctg gaccattcag aaagacagca
    20281 atgcccctca ccctaacacc actaaaatta ctgttaaaaa tgcccacaag accatcagcg
    20341 tgactggtat ttctatcggt ggaggaaata ttcaggtaac cgaactcaat ggttttgccg
    20401 tctctctcaa tatgaataca ccgactatca tcatcgttca tcaagatatt ccaggtatga
    20461 ttgcccttgt tacagaggcg ctttcccgct atggtatcaa tatcgcccag atgaatgtca
    20521 ctcgtgaaaa agctggtgaa aaagccatta tgattatcga agttgacagt cgcaactgtg
    20581 atgaggctat cgaagaaatt cgaaaaatcc ctcatctcca caatgtcaat ttctttaaat
    20641 aggaggaagc atgttttatt ctatcaaaga attggtcgag caagcagatc tggactttca
    20701 aggaaatgtc gcagaactca tgattacaac agagtttgaa ttgaccggtc gcgaacgtga
    20761 agaagtcttc cttctcatgg aacgcaatct ggaagttatg aaagcctctg tccaacttgg
    20821 cctcaatgaa aataaatctc gtagtggcct gacaggtgga gatgctgcca aattggatca
    20881 ctacatcgaa aacggaaaaa ctttatcaga ttacacgatt ctctctgctg cccgaaatgc
    20941 tatcgcagtc aatgaacaca atgctaaaat gggcttggtc tgcgctactc ctaccgcagg
    21001 aagtgccggt tgtctccctt ccgttctcac tgctgctatt gaaaaattag acctcagcca
    21061 cgagcaacaa ttggatttcc tctttgctgc tggtgccttt ggactagtca tcgcaaacaa
    21121 tgcctccatc tcaggtgctg agggtgggtg tcaagctgaa gttggttcag cctctgctat
    21181 gagtgctgcc gccttgactc tggctgcagg tggaacacct tatcaggcca gtcaagctat
    21241 tgcctttgtc attaaaaata tgctaggcct catctgtgac cctgttgcag gtttggtcga
    21301 agttccctgt gtcaaacgta atgccatggg agctagcttt gctttcatcg cagcagacat
    21361 ggccttggca ggtatagaat ctaaaatccc tgtggatgaa gtgatcgatg ccatgtacca
    21421 agtaggagca agcatgccaa ctgcctttcg tgaaacagct gaaggtggac tcgctaccac
    21481 ccctactggt cgtcgcctcc aaaaagaaat tttcggagaa taagcttatc aaataggaga
    21541 aaccatgacc tctatcacag cgattttttt cgatttggat ggaaccctcg ttgatagttc
    21601 tatcgggatt cacaatgcct ttacctatac ctttaaagag ctgggggtgc ctagccctga
    21661 tgccaaaact attcgtggtt ttatgggacc acctctcgaa agtagttttg cgacctgcct
    21721 gtccaaagac caaatttctg aagccatgca gatatatcgt tcttactata aggcaaaagg
    21781 catctatgaa gctcaactct ttcctcagat tatagacttg cttgaggagt tatcgagcag
    21841 ttatccactc tacatcacca cgacaaagaa tacatctact gctcaagaca tggccaaaaa
    21901 cttggaaatc catcatttct ttgatggcat ttatggttct agccctgaag caccccataa
    21961 ggcagatgtc attcaccaag ccttacagac acatcaacta gcaccagaac aagccatcat
    22021 catcggagat accaagtttg atatgctggg agctcgagaa acaggtattc agaaattggc
    22081 cgtcacttgg ggatttggag agcaagcaga tctactaaac tatcaacctg attatatcgc
    22141 tcacaaaccc ttagaagttt tggcgtattt tcaatagcat agactgggcg acaactctat
    22201 ttcagaagaa aatgaagtaa tactcaatga aaatcaaaga gcaaactagg aaactagctg
    22261 cgggctgctc aaaacactgt tttaaggttg tagatggaac tgacgaagtc agctcaaaac
    22321 actgttttga ggttgtggat agaactgacg aagtcagtaa catatacata cggcaaggcg
    22381 acgttgacgt ggtttgaaga gattttcgaa gagtataagt ctctacataa taaaacgcat
    22441 attaccaagg ttgtgtaact tgatactatg cgtttttctt ttttattcaa tgtgggttgt
    22501 ttgattagca aaggcgataa tagcttgctt caactcatct ccactgagag tgcggaactc
    22561 tccaatcttt tgattgatgg attctaaagg catgacatta accttaccaa cgaaaatctt
    22621 atccataact tgattatcaa cgagttcggt tgataccaag agttcttcgt agagtttttc
    22681 acctgggcgg attccaactt caacgattgg aatttcactt tcagtgtggc cacttagaag
    22741 caccatcttc ttggccaagt cataaatctt gactggtttg cccatatcaa ggataaagac
    22801 ttccccatct ttggcataag caccagcatg gataaccaga cggctagctt ctggaatggt
    22861 cataaagtaa cgggtcatgc ggaagtctgt caccgttaca ggcccacctt cagcaatctg
    22921 acgttcaaag actggaatga cactaccacg gctaccaaga acattcccaa aacgaactgc
    22981 acagtaggtt gattggctac gttggttaaa gccagtgaca atcaactccg ccacgcgctt
    23041 ggttgctccc ataacatttg gtggattgac tgccttatct gtcgaaatca taaccatctt
    23101 agacacttta gcttcatcaa cagccttagc aacattgtaa gttccacgga tattgttttt
    23161 gaaggcttct tttggattgc gctccatcat aggaacatgc ttgtgggctg ccgcatgata
    23221 aacaatagca ggtttgtact gctcaaagac ttgcaacaaa cgatcatagt cttgaatgtc
    23281 cgcaatcaca ggtacataat caatcccttg gaacttacga atcaattcat gataaacaag
    23341 gtagattgag ttttccccat gaccgagtaa gacaatgcgt tcaggattga agcgactaac
    23401 ttgacgacag atttcagaac cgattgaacc tccagctcct gtgactaaga tggtcttacc
    23461 tgtcagttct gcacccagac gcgattcgtc aagacggatt tcctgacgac ccaaaaggtc
    23521 cgtaatatca attttttgga agccagtacc tgcttggtga aggccctgaa caacagtttc
    23581 aaccttaggc atcttgtaac atttgacacc cagcttatta cacatctgca agatacgctc
    23641 atattctgac ggatccagcg acggaatcgc aacgatgaca cgctcgattt gatggcgttt
    23701 ggctaattca ggcagattgt cataagagcc caaaacagga ataccaccaa gtttttgacc
    23761 ctttttctta gaatccttat ccaaaatacc gaccagttct aattcactgg ttggatgttg
    23821 gtaactatcc ataaagagag ccccaccatc accggcacca atcaagaagg tccgacggtg
    23881 ttctccatca ccactacctt ttttgcgtct ggagtagatt aactgccaag taatccgtgg
    23941 caataaaatc aagaaggtac tcaacaagat aaagagaatg atgaaacgga tggagaagag
    24001 tggcaagaag gcataacaga tactatatga caagacactg ctagcagtca caccaaaaaa
    24061 gattttcatg aaatccgtaa tcttgctgta acgactaatg ctcgcgttca acccccaaaa
    24121 accaatcatc aattgataga acaagaaggc caaactcgta tagataatgt agtcaacagg
    24181 tgctggatta atcagcccat aaaataaaat ataagataca attatggaaa ccaccatact
    24241 gaaaatatca aatattcccc agaaaacctg cttttgttgt ttatttaaaa tttccaccag
    24301 atcaatcaca taatctgtta gttttttatt catagaaatc tactcctcct taaaagagtt
    24361 ttactatatt gttattatag catattttta tttatttggc ttattttatc caaataaatt
    24421 attgttctct tgtactcctt cttccattta aatcctctaa ttaaacctac aatcgtccca
    24481 aggccataag caaagtgaat ggaaaataaa agaaagggca tcacaattag aaatccattt
    24541 ttatgtttta ataaagtcag caaagtgagt aatgacaaaa gtagaaaata ggcacctaat
    24601 agtaaagtta tgaatacgaa tgtgatcggt aacaatgcta gactaaacac aagactcaaa
    24661 acaaataaac aaggaacata gtgaaataat gataaacact taaactgaac atgacttgtc
    24721 aagccaatcc acaaaccatt tgaatacttt tgatgcagca ttttcttgaa tgttggtcga
    24781 atatactgat aagatagaat acttgggcta tagcggattt tataaccatg ttctcgaatt
    24841 ctataatgaa tatcattatc ttcagttcgg ccaagttgct catttactaa accaaccttc
    24901 tggaaaacct ctcgtttata catcccatga aaaatagaag aaacatatct atcctcggaa
    24961 ctatttcgat aattggcaat gctactgcca aacatatttt cctcaacaag atgcaaggtc
    25021 tctgcccatt ttccttttcc ttcgacaatc gtcggtctag gccccccaca gacaaattca
    25081 ccttgttgaa taatagccac attgttcatt acaaaactct cagtaacttt tgaatgagca
    25141 tcaattttta aaataaggtc ccctacagaa tgtttaactc ccaggttaaa accactagct
    25201 tgatttttct taggattgtt atacaatcta attgagttaa actctgtatc ttcctttata
    25261 aattgctgaa tgatagctgt ggtcccatct gtggacatag catttataaa tagaatttca
    25321 acattctctt taggataggt ttgatttttt aagtcttcaa ttagaccagg cagatatttt
    25381 tcttcattgt atgcactgat tacaatggat acgagaagac tttcaacatt ttgagtcact
    25441 actactctcc tgaatttttc cttccaccat tctatcataa ttttcaagac tttcccattt
    25501 ttatcttgaa agccagaaac cttacttgac attatagtga aaaagcctta aaataagctg
    25561 ttattaaaat cagctagaag aggtattata tgaaaaagca atcactcttt tttgttccag
    25621 gtattatcct gattggtgtt tccttgcgaa ctccttttac tgttttaccc attattttgg
    25681 gaaatatttc gcaaggtctg gaggtagaag ttagttcgct tggtgtcttg accagcctgc
    25741 ctctccttat gtttaccctc ttttcaccat tttctacccg actggctcag aaaatcggct
    25801 tggagcatct cttcacctac agcctcttct tcttgaccat cggctcactc attcgactaa
    25861 tcaatctgcc cctgctctat ctaggaacct tgatggttgg ggcaagtgtc gcagtcatca
    25921 atgtcctgct tcctagtctt atccaagcca atcaaccaaa gaaaattggt tttctgacca
    25981 ccttatatgt aacgtctatg gggattgcaa cggctctggc ttcctatcta gctgtgccca
    26041 ttacacaagc cagttcttgg aaaggactta tcctcctcct cacgttactc tgtctagcaa
    26101 cttttttggt ctggctccca aatcaccgct ataatcatag actagctcca caaaccaaac
    26161 aaaaaagtca aataaaggtc atgcgtaata aacaggtttg ggcaattatt atcttttcag
    26221 gttttcaatc cttgatcttt tacaccgtca tgacctggtt acctaccatg tctatccatg
    26281 caggtctatc cagtcacgaa gctggcttgc tgacttctat cttatctctg attagcattc
    26341 ctttttcaat gaccatccca agcctgacaa ccagtttatc tactcgcaac cgtcagctca
    26401 tgctcactct ggtttcacta gctggtgtgg tcggcatttc catgctcttt ttcccaatca
    26461 ataatttcat ttactggctt accatccatc tcctcatcgg aaccgcaacc agcgccctct
    26521 tcccttatct catggtcaac ttttcactca agacaagcgc ccctgaaaag acagcccaat
    26581 tgtccggcct atctcaaaca ggaggctata tcctagcagc ctttgggcca accctctttg
    26641 gttacagttt tgacctgttc cactcttggg taccagctgt agctgccctc ttgctcatct
    26701 atatcctgat gactgtggcc ctctttacag tggacagagc ggataagatc ctttaaactt
    26761 ctagttttag ctagaagttt tttatatata aaaattttac acatttctct tgacagggct
    26821 ttcttttaga tgtacaatgt atgtgtagaa aaattatata taaaaatctt acacattaga
    26881 aaaggaggtt tcccatgtac tttccaacat cctctgcctt gattgaattt ctcatcttgg
    26941 ctgtactgga gcagggtgat tcttatggtt atgagattag ccaaaccatt aagctgatcg
    27001 ctaatatcaa agaatccaca ctctatccca ttctcaaaaa attggaaggc aatagctttc
    27061 tgacaaccta ttctagagag ttccaaggtc gcatgcgcaa atactactcc ttgacaaacg
    27121 gtggtataga gcagctcttg accctaaaag atgaatggac actctataca gacaccatca
    27181 atggcatcat agaagggagt atccgccatg acaagaactg aatacctgac tcagctagaa
    27241 ctctatctca agaaactacc tgaagctgac cgtatcgaag ccatggacta tttcagagag
    27301 ctctttgacg atgctggagt cgaaggagaa gaagaactca tcgctagttt gggaactccc
    27361 aaagaagcgg cccacgaagt tctatccaat cttctcgata aaaaaatcaa tgaagcaccc
    27421 gctcaaaaaa ataaccgaca aattttacat atcgccttgt tagccctcct tgcagcacct
    27481 atcggcattc ctctgggaat cgccatcctc gtgaccctgt tcgcaatcct tgtagccgct
    27541 ttgactgtca ttctggcttt ctttgcagtt tccatactgg gtatcatcgg cggattccta
    27601 tttttagttg aaagtttcac tgtcctcgcc caagccaaat cagcctttat cttgattttt
    27661 ggttctggtt tactggctat cggtgcttct tcgctagttt tacttggcat ttcctatgta
    27721 actcgcttct tcggtctact cattgttcgt ctggtacaat ttgttcttaa aaaaggaaag
    27781 agaggtaacc agcatgcgta aatggacaaa aggatttctc atctttggtg tggtgactac
    27841 cgttatcggc tttatcctgc tttttgtagg tatccaatct gacgggatta agagcctact
    27901 ttccatgtcc aaagaacctg tctatgatag ccgtacggaa aagctaacct ttggcaagga
    27961 agtcgaaaac ctagaaatta ctctccacca acacacgctc accatcacag actctttcga
    28021 tgatcaaatc cacatttctt accatccatc tctttctgct caccatgatc ttatcaccaa
    28081 tcagaacgat agaactctga gtctcactga taagaaactg tctgaaactc cgtttctctc
    28141 ttctggaatt ggtgggattc ttcatatcgc aagtagctac tctagtcgtt ttgaagaagt
    28201 tattctccga ctaccaaaag ggagaactct aaaagggatc aacatctcag ccaatcgcgg
    28261 acaaaccacc atcataaatg ctagccttga aaatgcgacc ctcaatacaa acagctatat
    28321 cctccgaatt gaaggaagtc gtatcaaaaa cagtaaactc acaacaccca atatcgttaa
    28381 tatctttgat acagttctta cagatagtca gctagagtca acagagaatc acttccacgc
    28441 tgaaaatatc caagtccatg gtaaggttga actgactgcc aaagattatc tcagaatcat
    28501 cctagaccag aaagaaagcc aacgaattaa ctgggacatc tcaagcaact atggttctat
    28561 cttccaattc acaagagaaa agcctgaatc aagaggtacg gaattaagca acccttacaa
    28621 aactgaaaaa accgatgtca aggatcaact cattgcgaga tctgatgata atattgatct
    28681 aatatccaca ccaagcagac gttgacaaaa acgcttacat ctgctactat ggaagcatat
    28741 ttatctaact aaaaaggagg ttctaccatg aaacaagaat ggtttgaaag taataatttt
    28801 gtaaaaacaa caagcaagaa caagcctgaa gagcaagctc aagaggttgc agacaaggct
    28861 gaagaaacga tagccgattt cgatacacca attgaaaaaa atactcagtt agaggaggaa
    28921 gtctctcaag ctgaagtcga actggaaagc cagcaagaag agaaaattga aactcctgaa
    28981 ggcggtgaag cgagaacaga aatagaagaa aagaaggcat ctaattctac tgaagaagag
    29041 ccagaccttt ctaaagaaac agaaaaagtc actatagctg aagagagcca agaagctctt
    29101 cctcagcaaa aagcaaccac gaaagagcca cttcttatca gtaaatcttt agaaagtcct
    29161 tatatccccg accaagctcc aaaatctagg gataaatgga aagagcaagt gcttgatttt
    29221 tggtcttggc tagtggaagc gatcaaatct cctacaagta agttggaaac aagtatcaca
    29281 cacagttaca cagcctttct cttgctcatt ctgttttctg catcttcctt tttctttagt
    29341 atctatcaca tcaaacatgc ttactatgga catatagcaa gcattaacag tcgcttccct
    29401 gagcagctag ctcctttaac tcttttttct atcatctcta tcctagtagc gacaacactc
    29461 ttcttctttt cattcctctt gggtagtttc gttgtgagac gatttatcca ccaggaaaag
    29521 gactggacgc tagacaaggt tctccaacaa tatagtcaac tcttggcaat tccaatcttc
    29581 ctcactgcta ttgctagttt ctttgctttc tttgatagcc tacgatttac agctctcttg
    29641 tgtgtgatta gcattggaat cattctgctt gccagtctcc atatcattac aagaccaagt
    29701 caagcaagtg aaaccgactc cttctatcaa ttattcttgt ctgtccttgt gaacggagtt
    29761 attatcctcc tcttctttgt agctgaagtg gcactgattg gagattatct tcgtatcttg
    29821 gcctttcttt aaaattcaat cctgtcatcc ttggcaggat tttttctatg tcaaaaaagc
    29881 aagtcgattg acctgcttct gctttacttt tcttgtgcta atgttttaaa atcttgtact
    29941 aggatgggtt gtatttctat ttgattggcg tctagttggt ggtaaaaaga tgggggtaat
    30001 acctctaaga attttgcata gtccaagcga gctatggatt catagtcttc tggtttagag
    30061 tcgtctcctg tgatttgaac caagtcaatc tcccactgga cttccttatc caccaattgc
    30121 tcaatatagg ctgcaggaac aaacggttct ctcggtaaaa ctgtcttgac tccttgagct
    30181 agatggtaaa cgccatgcac ttttccttct ccatcctgat agaaggaaac tctcgcaaag
    30241 taggcatctg tctcttgaac cgcacgcaca cgcgcttcaa actgagccaa gccatctgcc
    30301 tctaaaaagc ttttcaagtt ctcacgacta aagaaaatag gattaaaaat tccttggcaa
    30361 atcgtaaaac gagctacagg gtctgctaga taggcttgaa tacttgcttg gaaataagct
    30421 tcaaaatcaa aaccatctag cccttcaata tcagtccctg tataagcaag caaagcatct
    30481 aaaaatgact tgataatctg ccagtctgtc tttgttagta ggtcaggaag atcgacacgg
    30541 taagcctttt gaccatcagc ataactgacc ttaaaaagaa attgtgattg ccccactatc
    30601 gcacactcaa tatactcgag acgattaaga ggctgacgga gatagactac atcatagcta
    30661 tgtgactcca aaccgtctag caaggccaag atcgacttgg cattcaaaat ctcttgttct
    30721 cctaaaatgc tctgtttatt tggaataaaa aatgttttcg ccataactgg actcctttga
    30781 aatcgtttac atacagtata ccttattttt ctgaaagata caaaaacaaa ctttagattt
    30841 ttgagtacaa agcatagaaa aacagcccct gaggactgtt tgatcttata cagtagctgc
    30901 ctgatccaag ctttcaccga tagcggctag gcgctcaatc acttcagctt gtgtcaattc
    30961 attttttgaa acatagcggt tacgtgggtg aacacggcac tcgtgtgagc atccacgaag
    31021 gtacttgtct tcattttctt ctgatgtcaa gatacgacgg ttacagaagg gatttccaca
    31081 gttgacataa cgttcacatg gtgttccatc aaaccagtct ttccctacga tggttgggtt
    31141 gacatggttg acatcaacgg cgatacgctc gtcaaatacg tacatttttc catcccaaag
    31201 ctcaccttga acttctgggt ctttaccgta agttgcgatt cctccgtgca attggccgac
    31261 atctttgtag ccttcacgga ccatccagcc tgagaatttc tcacagcgaa cgccacctgt
    31321 acagtaaacc acgacacgct tgtccatgaa tttttccttg ttatcacgga cccattgtgg
    31381 taactcacgg aagttgcgaa tatctgggcg aatagctcca cggaaatgtc ctaggtcgta
    31441 ctcataatcg ttacgtgtgt caaggacaac ggtatcttta tcaagaagcg cttctttgaa
    31501 ctcttttgga gacaagtaag cacctgttgt ttcaagtggg ttgatgtcat tgtcaaagtc
    31561 gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag cgaacaaaca tcttcttgaa
    31621 ggcttgttca ttttcttcgt caatcttgaa ccagagttct tccattcctg gaaggctgtg
    31681 aacgtagtcc atgtattttt gagttgtttc atagtcacct gaaactgttc cgttaattcc
    31741 ctcgtcagcg actaggatac ggcctttaag gccgattgat ttacagaaag ccaagtggtc
    31801 tgcagcaaat tgctctgcat tttcaattgg agtataaagg tagtaaagta agacacgaat
    31861 atcttttgcc ataagatttg ttctcttttc tattcttaaa ttttctaaat tttttattta
    31921 tctacactag tatacctgct tgagaaaacg aatgcaattt atttgactgg aaattgtaga
    31981 gggttctcga aatttcctga atggttaaaa taaggacaag agaaaacatg gatatctata
    32041 tccttgtgcc aaaaaaacca ctgccctccc cagaccaacc tgaggaaagc agtgattctt
    32101 attttaggag ttaggaatga atacacgaaa tcaatttagc tgattatttt ttgtttttca
    32161 agaattcatc gtattgtttt tgcatttcgt tcaatacttt ttcgtaggca ccttcagatt
    32221 tcaatttttc catcaattct ggaatcgctt tatctgggtc tacagtacca gtgttgatag
    32281 ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat ttcagatttc acattgtcag
    32341 tattgaagat aaatccaagc gctggagatt ctttagcttc tgccaattct ttcttagaat
    32401 tttcgatttg ttggtctgta acgttttcgt tgatgtaaag gatccagttg ttaccagtgt
    32461 tccatccacc catgtgagtg tttcctttgt agccatcaag aacgcgaaca cggttttctt
    32521 taccttcaat tttttcccag ttcttgcctt ctggaccgta aacaagaccg ttcaagagtt
    32581 ctggattcgt attcaagagg ttcaagattt ccattgattt ttctttgttc ttagagttgt
    32641 ttgagatgac aaagttagca acttgtgttg tttggttttt cttgatgaag ttagtaattg
    32701 gtttgatttg gatatctttg ttggcaacac gtgaaagcaa gctgttaccg tagtcagctg
    32761 gtcctactgt ttcttcacga acgaaccaag tatcttgttg aaggtcaaag gaagtatcgc
    32821 ttgttgcgac atcttttgga atgtagccag cttcatagaa tttgtgaaga gtcttcaagt
    32881 gttctttgaa acgaggcact tcgtaacggt ttacaacttt agtagtatcg ccttcaaggt
    32941 caataacgaa tggaagcccg tttgctactg ggtagtcaaa gttatcagat gggatgaaaa
    33001 ctttaccaat agcaaatggt actacgtctg gagctttttc tttaatttgt ttcaagactg
    33061 gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat accatatttg gcaaggagag
    33121 ttccgttgaa ggcaaagttt tgagatgatg caacgttggc tgcaactgga acagcgtaaa
    33181 ttttaccgtt tacagtatta cccttgatgt aagctgggtc aagtgccttg taaaggtctt
    33241 taccttcttt tttgtacaat tctgtcaagt cagcataagc acctttttga gcatttacaa
    33301 tatagttatc tgcaaaggcg atatcatagt tttcaccaga tgatgtgata actgacattt
    33361 tcttaccata gtcaccccag ccaaggtatt ggatatccaa tttagcacca actttttctt
    33421 cgatgatttt gttggcattt gctaacaatt catccaagtt atctggtttg tcaccgattt
    33481 ggtacatttt gataacaggt ttgtcacctg aatcagcagc ttttttgctg ttacctgtca
    33541 agttgccaca agcagcaaga cctgcagcca gagcgactac actagcagat gcaaaagcat
    33601 attttttcca gtttttcatg ataaaaactc ctttttttat ttttaaactt ataaacaatg
    33661 taatgatctt atactcaatg aaaatcaaag agcaaactag aaaactagcc gcaggctgct
    33721 caaagcactg ttttgaggtt gtagataaga ctgacgaagt cagttacata tatctacggc
    33781 aaggcgacgt tgacgcggtt tgaatttgat tttcgaagag tattaacttc acacaaggga
    33841 agttgggaac tgagaaatgt tctttttcaa taagcactat tctttcacac caccgatagt
    33901 caaacctttt acaaagtagc gttggaagaa tggatataaa atcgcgattg gaagggttgc
    33961 aaccacaacc atggccatac gacctgtttc tttcggtaga gcaactccca gttgaccagt
    34021 caagccgacc gctttggcaa tgtagtccat attttgttgg atttgcatga gcaaatattg
    34081 caatggatac aagttatcac tcttgatgta aagaagggcg ttgaaccagt cattccagaa
    34141 accaagagct gtcaaaagcg tgatggttgc gatacctggt agtgacaatg gcaaacagat
    34201 ttggaagaaa atccgggcct cactggcacc atcgatacga gccgattcga gaatggcttc
    34261 tggaatggtc ttcttgaaga aggaacgcat caagatgata ttgaatggtg agagaagcat
    34321 tggaacaatc aaggcccaaa cagtgtcccc aagctgaagt acacgggtca ccatgatata
    34381 acctggtacc aaaccagcgt tgaacaacat actgagaagg acgaagatgg taaaaaatct
    34441 gcgatactta aaggttgtcc gtgaaatagc gtaggcatag gttgttgtga taaagacatt
    34501 tgtcaatgtc ccaactacgg ttacaaagac agagatgaag agggcttgta ggattttatc
    34561 cttaaactgt gccaaaaact caaaaccgtc taagccaaat tgggatggga agaagctata
    34621 gccgtattgg aggaggcttt tctcgtctgt cactgaaata atgataacga atacaaaagg
    34681 taggatacaa gagagggcaa tcaaacccga aatgatactg aagaagatat ctgctttctt
    34741 actgaaggag tgaatgccga cattatcaat tttttctttt ttaattttct tttttgccat
    34801 attctcctcc tttctagaac aaagctgagt ttggatcgac tcgtcttgca agcaagtttg
    34861 ataggataac cagaatcaaa ccaacaacgg attggtaaag accggctgct gcagccatac
    34921 cgatatctgc tgtctgagtc aaaccattaa agacatatac gtccaaaacg ttggttacat
    34981 tgtaaagctg accagcattg tgtgggattt gatagaagag accgaagtct gcgcggaaga
    35041 tatttccgac tgcaaggatg gtcaatacag ttacaagcgg agtcaactga ggaatggtta
    35101 cgttgcgaat acgttgccac ttgctagctc cgtccactgt cgctgcttcg tagtaggttg
    35161 gatcaattcc catgatcgtc gcatagtaca tgacactgct atatccaaat cctttccaaa
    35221 tacctaggaa aagtaggaga tagggccaga tgcccaggtc agcgtagaaa ttgacttctt
    35281 tgagaccaag actttccaat agatgattga acaccccttt atcaatattt aggaaggcat
    35341 ctgtaaagaa actgatgata acccaagaca agaagtaagg gaacaacata gaagtttgaa
    35401 aaatcttcac cattctctta gaacggagct cgctgaggat aatggcgatc cctacagata
    35461 caactaaacc tagaaagata aagccaagat tgtagaggac agtatttcgt gtgataataa
    35521 aggcgtctct tgaactaaat aagaatctaa aattatcgag tccgacccat ttactattta
    35581 tgatactatc tatgaaacca ttactggtca tgtggtagtc tttgaaggca accacgttcc
    35641 caaatactgg aatgtaaaag aatagaatca accagagtgc ccctggcaaa accatcaaga
    35701 gaaagatcca gttgtctctc aatgtttttg aaaacttttt cataatttcc tcccttttta
    35761 ttttgatatc catctaaaaa ttctttttta gacttttgat aacgattaca ttattagtat
    35821 actcctattt gcaggttagg ttaaactcct aattatagaa aaaactccac aaattatgta
    35881 gcagatttaa aactttatca ccactatcaa acaaatgtcc taaatcaatt gtttatttta
    35941 tctctattag cccagtgatg gcgtcactct gttataagca tccaacaacg gggtatactg
    36001 aaaaatctcc agactaggga actcagcgat agttcctaat ctggagattt ttaatatgtt
    36061 attaggcgtt tgctttcaac ttagcaataa cctctttaag attatcaatc aactctgctg
    36121 cagtatgctc agagcctttt tcatctgcca agaacaaaac tgctttttga agttcttttt
    36181 gagagttttc aaggacatcc ttatctactg tttcaaggtt tgagtcttta agaagtttac
    36241 ttaattcctt ggctaatttc ttgagtttga tttgcagact catcttctcc tgctgtttct
    36301 ttgcccgctg tttgtcctcc atccttagtt gctgactggc tttccttaat ggactctagg
    36361 gaagcaatgg catctttgac tgtttgcaag atatcacgta aaccttgctc tgtcaaacta
    36421 tcatctgtaa gagctttctt agcctctgcc aaaaccagac gtgctgaatc tgtggtagga
    36481 ttcgatacac ctgtcaatga tctcaaaaga ttttctaagg tttgagtctg cttactaata
    36541 ctagactaaa atcaaaaagc attacataac agtgatatga aatcaactaa agaagaaatc
    36601 caaaccatca aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa
    36661 atcgttctat agtaaaatga aacaagaaca ggacaaatcg atcaggacag tcaaatcgat
    36721 ttctaacaat gttttagaag tagatgtgta ctgttctagt ttcaatccat tatatttcgt
    36781 ctgatgggca aatcttataa agagattata gaacttttat agtagtttga aataagatgt
    36841 gaacaactct atcaggaaag tcaaattaat ttatagaaat attttagcag ccaaggtgta
    36901 ctgttataga ttcaatacac t
//
LOCUS       DAVLAQ010000016        35699 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000016 DAVLAQ010000000
VERSION     DAVLAQ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.016"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(116..1750)
                     /locus_tag="VXB71_000798"
     CDS             complement(116..1750)
                     /locus_tag="VXB71_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450940.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1731..2480)
                     /locus_tag="VXB71_000799"
     CDS             complement(1731..2480)
                     /locus_tag="VXB71_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450941.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            2659..4113
                     /locus_tag="VXB71_000800"
     CDS             2659..4113
                     /locus_tag="VXB71_000800"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0450942.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4203..6821)
                     /gene="alaS"
                     /locus_tag="VXB71_000801"
     CDS             complement(4203..6821)
                     /gene="alaS"
                     /locus_tag="VXB71_000801"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0450943.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPCITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6843..7328)
                     /locus_tag="VXB71_000802"
     CDS             complement(6843..7328)
                     /locus_tag="VXB71_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0450944.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7603..7842)
                     /locus_tag="VXB71_000803"
     CDS             complement(7603..7842)
                     /locus_tag="VXB71_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450945.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8103..9173)
                     /locus_tag="VXB71_000804"
     CDS             complement(8103..9173)
                     /locus_tag="VXB71_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0450946.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9170..9943)
                     /locus_tag="VXB71_000805"
     CDS             complement(9170..9943)
                     /locus_tag="VXB71_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450947.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9940..10746)
                     /locus_tag="VXB71_000806"
     CDS             complement(9940..10746)
                     /locus_tag="VXB71_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0450948.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10727..11884)
                     /locus_tag="VXB71_000807"
     CDS             complement(10727..11884)
                     /locus_tag="VXB71_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0450949.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12044..12949)
                     /gene="murB"
                     /locus_tag="VXB71_000808"
     CDS             complement(12044..12949)
                     /gene="murB"
                     /locus_tag="VXB71_000808"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0450950.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13061..13813)
                     /locus_tag="VXB71_000809"
     CDS             complement(13061..13813)
                     /locus_tag="VXB71_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0450951.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13823..14554)
                     /gene="budA"
                     /locus_tag="VXB71_000810"
     CDS             complement(13823..14554)
                     /gene="budA"
                     /locus_tag="VXB71_000810"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0450952.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14696..15967
                     /locus_tag="VXB71_000811"
     CDS             14696..15967
                     /locus_tag="VXB71_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0450953.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15987..16802)
                     /locus_tag="VXB71_000812"
     CDS             complement(15987..16802)
                     /locus_tag="VXB71_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0450954.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(16959..17612)
                     /gene="phoU"
                     /locus_tag="VXB71_000813"
     CDS             complement(16959..17612)
                     /gene="phoU"
                     /locus_tag="VXB71_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0450955.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17624..18382)
                     /gene="pstB"
                     /locus_tag="VXB71_000814"
     CDS             complement(17624..18382)
                     /gene="pstB"
                     /locus_tag="VXB71_000814"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0450956.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18395..19198)
                     /gene="pstB"
                     /locus_tag="VXB71_000815"
     CDS             complement(18395..19198)
                     /gene="pstB"
                     /locus_tag="VXB71_000815"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0450957.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19209..20093)
                     /gene="pstA"
                     /locus_tag="VXB71_000816"
     CDS             complement(19209..20093)
                     /gene="pstA"
                     /locus_tag="VXB71_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0450958.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20083..21000)
                     /gene="pstC"
                     /locus_tag="VXB71_000817"
     CDS             complement(20083..21000)
                     /gene="pstC"
                     /locus_tag="VXB71_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0450959.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(21000..21878)
                     /gene="pstS"
                     /locus_tag="VXB71_000818"
     CDS             complement(21000..21878)
                     /gene="pstS"
                     /locus_tag="VXB71_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0450960.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22452..23756)
                     /locus_tag="VXB71_000819"
     CDS             complement(22452..23756)
                     /locus_tag="VXB71_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0450961.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23757..24530)
                     /locus_tag="VXB71_000820"
     CDS             complement(23757..24530)
                     /locus_tag="VXB71_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0450962.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24520..24798)
                     /locus_tag="VXB71_000821"
     CDS             complement(24520..24798)
                     /locus_tag="VXB71_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0450963.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24798..25199)
                     /locus_tag="VXB71_000822"
     CDS             complement(24798..25199)
                     /locus_tag="VXB71_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0450964.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25409..26026)
                     /locus_tag="VXB71_000823"
     CDS             complement(25409..26026)
                     /locus_tag="VXB71_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0450965.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(26016..26789)
                     /locus_tag="VXB71_000824"
     CDS             complement(26016..26789)
                     /locus_tag="VXB71_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0450966.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26800..27537)
                     /locus_tag="VXB71_000825"
     CDS             complement(26800..27537)
                     /locus_tag="VXB71_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0450967.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(27542..28672)
                     /locus_tag="VXB71_000826"
     CDS             complement(27542..28672)
                     /locus_tag="VXB71_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0450968.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28756..29145)
                     /locus_tag="VXB71_000827"
     CDS             complement(28756..29145)
                     /locus_tag="VXB71_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0450969.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29161..29544)
                     /locus_tag="VXB71_000828"
     CDS             complement(29161..29544)
                     /locus_tag="VXB71_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0450970.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29545..30333)
                     /locus_tag="VXB71_000829"
     CDS             complement(29545..30333)
                     /locus_tag="VXB71_000829"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0450971.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(30326..31261)
                     /locus_tag="VXB71_000830"
     CDS             complement(30326..31261)
                     /locus_tag="VXB71_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0450972.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31391..31567)
                     /locus_tag="VXB71_000831"
     CDS             complement(31391..31567)
                     /locus_tag="VXB71_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0450973.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31707..32414)
                     /locus_tag="VXB71_000832"
     CDS             complement(31707..32414)
                     /locus_tag="VXB71_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0450974.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32565..33593
                     /gene="queA"
                     /locus_tag="VXB71_000833"
     CDS             32565..33593
                     /gene="queA"
                     /locus_tag="VXB71_000833"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0450975.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFY
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34254..34643)
                     /locus_tag="VXB71_000834"
     CDS             complement(34254..34643)
                     /locus_tag="VXB71_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0450976.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(34697..35389)
                     /locus_tag="VXB71_000835"
     CDS             complement(34697..35389)
                     /locus_tag="VXB71_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0450977.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVFVPFATKYEADNDLSAGQEQEITLGKNGKIVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        10630 a         8170 c         6756 g        10143 t
ORIGIN      
        1 tcaaaacatt cctccctata tttttgatta ccaatcttaa tcatttacaa ctacattcta
       61 acaaactata aaagcgtttg tcgaattgaa tttatcaagc aagcaaccaa ctatctcatc
      121 ttttttctat ttctgccaat atgcgtgaca ggtaataatg atagccaaaa atagcaagag
      181 caagcaagac gataagagct cctactccca agttgatggc aaggataggg gagagagact
      241 gaaccaagaa tatgctccca attacaaggg ccatcaggat tgcactataa ataaacaata
      301 aaactatggc gactatgcca tttgaacgat tcaccaggtc cgtaatgcta ctccaattgg
      361 ttgacagatt tttaacgtcc ttaaagtaat ggtggcaaga aaggatgaca ctggcaatga
      421 tccagactac aagaaggtaa atcatcgaaa ggatggacaa gcctagatat agagaaagac
      481 cgagcaaagt cagaactggt aaaaaggact gaacagcaaa gataatccaa aatttcactt
      541 tcacataacg agcaaagtca aagggtaaac tcttcagaaa atcaacattt tccctctcca
      601 aggacaaggc aattgaatgc aggctggtga tattgttatt gacaactgct ataaacactc
      661 ctacaaaaaa caagggtaac cagtatggag gatgaatgtc tggaactatc tgagaatctc
      721 ggattttgga aatcagactg atcatcatga gataaggaag gaaagcactt gtaaaaagca
      781 ctgtaatcac accagtcccc tgtcccaaga gggtgaggtg gtagcgtaaa accatacgga
      841 aaaagccctt tttagtagtt gaaatcctct ccttgctgcg acgttctttt ttgaccttct
      901 cctcactgtt aagcaggatc acgtcataaa aacgaggaag gaccttcttt ttggtcagat
      961 aaagcaggaa gagagttagt cctatccaag cgagcagacc cactaaggct tctgtcgaaa
     1021 aaggctccac tgctattttg taaaagatat gaagaggata aaggagaaat ggaatgtctc
     1081 taactttgtc aacaatactt ccaaaagtcg actgaagaaa gaagataaat attaaaggta
     1141 tgagaactcc tatcccaatc atcacattcg aaaaaataga ctgatacttt ctgaagaccc
     1201 tagtctgagc caagaaatgt actgccacta ccgtcactaa agtaacagag acaaataata
     1261 aggtcaagga cagtagcatc aaaggcaaac ccagccaaag agaaggagct agactaatat
     1321 agagggctag aaaataagct aggattggta caattccagt tagagctggc aagaggacag
     1381 acagaccttt ggccattata atctctgatt ctttaaaggc atagggccta taggaggcca
     1441 ggtccttact ctcataaaag acattgtaaa aggcagtgaa agaagttgaa aaggccagca
     1501 ccagtaaaat agcaaccatc gagctaaaat aaataggcat ttcctcaaaa ggaaaatgaa
     1561 tggctatatt actaaaacag atgagcatca agagactgga aaaaatgtaa gaacttagga
     1621 ctctagcaga aacatttact tttttcccag gattcttagc ctgcttcttt cgtagattag
     1681 ccagattagc ttcttgagat gaatagagga tattgatatc aactaatttt ttaatgacct
     1741 tgagacgcat ccgcaacctc ctcttttcta ccagcaagac taaggtagat actttccaaa
     1801 aactggtctg ggtggtcttt cctcaagtcc tctaccttac cacaataaat caaatgcccc
     1861 tttttcaaaa tggcaatccg atcacagact tgctctgcca cctctaggac atgagttgaa
     1921 aacaagactg tcttcccttt ttgtgcatgt tccttcatca tctgtttcaa atcaaaggca
     1981 gcctggggat ccaaaccagt caagggttca tccaagaccc aaatatcggg atcagacaag
     2041 agtgctccga tgacaaagac tttctgacgc attccgtgag aaagagtttc aataacctga
     2101 tagcgatttt cagcaaaatc aaaaacgttc aatagcctag ctagactagc ctccaagtca
     2161 gatctactca gatcatagga tgaggcgatc aattcccaaa attcattggc cgttaagcgt
     2221 aaaaataagt caggcgagtc tgctacgtag ccaatctttc gtttaatagc caagcgattt
     2281 tccgataact cctgaccgtc taccaaaata cgaccactgc tgggtgaaat gatactgact
     2341 agggatttta tggtggtcga ttttccagcc ccattatgac caatcaagcc cataatctct
     2401 ccattttcaa tctgcaaatt gagattactc aaggcctctt tatcaccata caacttacta
     2461 acattttgaa attcaatcat gggacaactc ctatctttat ctgtattata catcgctata
     2521 ctagcacttt gatacaaaaa aatcaatact ttattttaag tagttaaaat agtttccttc
     2581 tatcttacgc aaacgtttgc accaagagat actttatgat agaataaaga acaagattga
     2641 caagtaagag gaaacatcat gcaaaatcaa acactcatgc aatactttga atggtatctg
     2701 ccccacgacg gtcaacactg gacgcgtctg gctgaaaatg ctccacacct agctcatctg
     2761 gggatcagtc acgtctggat gccaccagcc ttcaaggcaa ccaacgaaaa agatgtcggc
     2821 tatggggtct atgacttatt tgacttagga gagttcaacc aaaaagggac tgtccgcacc
     2881 aagtatggtt tcaaagaaga ctatcttcaa gccattcaag cccttaaagc acagggaatt
     2941 caacctatgg ccgatgtagt tctcaaccac aaggctgctg ccgatcacag ggaagccttt
     3001 caggtcatcg aagttgatcc tgtagaccgt acagttgaac ttggagaacc cttcaccatc
     3061 aatggctgga ctagttttac cttcgatggt cgccaagata cctataatgg cttccactgg
     3121 cattggtacc acttcaccgg tacagactac gatgccaaac gcagtaaatc tgggatttat
     3181 ctgatccaag gggacaacaa gggctgggct aacgaggaat tggtcgataa cgaaaacgga
     3241 aactacgact acctcatgta tgccgaccta gactttaaac atcctgaagt catccaaaac
     3301 atctatgact gggctgattg gttcatggaa acgactggtg tagctggttt ccgtttggat
     3361 gccgttaagc atattgactc tttctttatg cgcaacttca tccgcgatat gaaggaaaaa
     3421 tacggtgacg atttctatgt ttttggtgaa ttttggaacc cagacaagga agccaatctg
     3481 gactatctcg aaaaaacgga agaacacttt gaccttgtcg atgttcgtct ccaccagaat
     3541 ctctttgaag ccagtcaagc tggcgcaaac tatgaccttc gtggcatttt cacagatagc
     3601 ctggttgaac tcaagcctga caaggctgtg acttttgtcg acaaccacga tacccaacga
     3661 ggacaagccc ttgagtctac cgttgaagaa tggttcaagc cagcagccta tgccctcatt
     3721 ttgttacgcc aagacggcct tccatgtgtc ttttacggag actactatgg gatttcaggg
     3781 cagtatgctc aacaagattt caaagaaatc cttgaccgcc tcctagccat ccgaaaagat
     3841 ttggcctatg gagaacaaaa tgactacttt gaccatgcta actgtatcgg ttgggtacgt
     3901 tcaggtgctg aaaatcaatc cccaatcgca gtccttatct caaatgacca agaaaacagc
     3961 aagtcaatgt ttgtcggtca agaatggact aatcaaacct ttgtagattt acttggtaac
     4021 caccaaggtc aagttacaat tgatgaggaa ggttatggac aattccctgt ctcagctaga
     4081 tccgtaagtg tctgggcagt caataccatc taatagctca taataaccaa gctaggtcca
     4141 agcggatttg gcttttttgt attcacaaaa agacctaccc aaatggatag atctttactt
     4201 gattacaatt tacctgctac tgcatccaac aattcttgga tcttagcttg gttgcttcct
     4261 cctgccatgg ccatgtctgg tttaccacca ccacgtccat cgatgattgg tgctaattct
     4321 ttgacaaggt ttcctgcatg aaggtctttt gtcttgcttg ctacaaggac attgactttg
     4381 tcaccgatag cagcaactag gacaagaaga tcagagtagt ctttttgttt ccagttatct
     4441 gcaaaggtac gaagggcacc ggcatctgat acagacactt gactagcaat gtagcggtga
     4501 ccgttgactt ccttcacatc cttgaagata tcgcctgcgg ctgcagctgc ggctttttct
     4561 ttcaactcag cattttcttt ttgaagttga cgaagttgtt cttgaagtcc ttctaccttg
     4621 tgaggtactt ccttgacttg aggtgctttc aaggttgctg caacagcttt aagagcgtcc
     4681 tcttgttcac gataggcttc aaaggcttcc ttaccagtca ctgccaagat acgacgagtt
     4741 cctgaaccga ttccttcttc tttgacaatt ttgaagagac caatctcaga agtgttgcca
     4801 acgtgggtac caccacaaag ttcaatagag tagtcaccga tagtcacgac acgaacttcc
     4861 ttgccgtatt tctcaccaaa gagggccatc gctcccattt ctttagcagt gtcaatatcc
     4921 gtttcaactg tcttaacttc aagagcttcc cagatttttt cgttgacttg ctgttcaatc
     4981 gcacgaagtt cctcagcagt tactgcttgg aagtgggtaa agtcaaagcg aaggaattca
     5041 acttcgttaa gagatcctgc ctgtgttgcg tggtttccaa ggatattgtg aagggcagcg
     5101 tgaagcaaat gagtcgcagt gtggtttttc atgacacggt gacggcgatt gctatcaatt
     5161 gccaaggtat attcttggtt caaggcaagc ggtgcaagga cttcaactgt atgaagggct
     5221 tgaccatttg gggctttctg aacattggtc acagtagcca caaccttacc tgactcatcc
     5281 aagatttgtc cgtagtcagc tacctgtcca cccatttcag cataaaatga cgtttccgca
     5341 aagataagag aggcagttcc ttctgaaaca gcttctactt ctgcattgtc cgccacgata
     5401 gctaccaatt tagaagacaa ttggctagca ttgtagttga agacactttc tacagtgatg
     5461 ttttgaagag tttcattttg catacccatt gagccaccct tgacagctga ggcacgcgcg
     5521 cgttcttgct gttctttcat ggctgcttca aaaccttcac ggtctacagt cataccagct
     5581 tcttcagcga tttcttcagt caattcaact gggaacccat aagtatcata gagtttgaag
     5641 acatctgaac cagcgataac agattgacct ttttctttca agtctgctac aatgccttgg
     5701 gcaaagtgtt gacctgagtg aagggtacgg gcaaatgatt cttcttcgct cttaacgatt
     5761 ttctcaataa agtcacgttt ctcaagcact tctgggtagt agctttccat gatttttcca
     5821 acagttggaa ccaatttgta aaggaaaggc tcgttgatac ccaatttttg accatgcata
     5881 gaagcacgac ggagaagacg acgaagaaca taaccacgac cttcatttcc tggaagggca
     5941 ccatcaccga tagcaaatga aagagaacga atgtggtctg cgataacctt gaagctcatg
     6001 ttgtcgccat cttggtcata aaccttacca gacaatttct cgacttcacg gataatcggc
     6061 atgaagaggt ccgtttcaaa gttggtctta gccccttgga taacggccac caaacgctcc
     6121 aaaccagcgc ccgtatcaat gttcttatgt ggcaattcct tgtattcgct acgaggaaca
     6181 gcagggtctg cgttaaattg tgacaaaacg atgttccaga tttcaatata acggtcgttt
     6241 tcaatatctt ctgcaagcag gcgaagaccg atattttctg ggtcaaaggc ttccccacgg
     6301 tcaaagaaga tttctgtatc tggtccagaa ggtcccgcac cgatttccca gaagttgtcc
     6361 tcaattggaa tcaagtgact tggatccact cccacttcaa tccagcggtt gtaagaatct
     6421 ttatcgtctg gatagtaggt catgtaaagt ttttcagcag ggaaatcaaa ccattcaggg
     6481 cttgtcaaaa gctcataagc ccaagtgata gcttcgtcac ggaagtaatc cccgatagag
     6541 aagttcccca gcatttcaaa catggtatgg tgacgcgcgg tcttccctac gttttcgatg
     6601 tcgttggtac ggatagcctt ttgggcattg gtaatacatg gattttcagg gataatggtc
     6661 ccgtcaaagt atttcttaag ggttgctacc ccagagttga tccacaaaag agttgggtca
     6721 tttacaggaa ccaaacttac tgatggttct actgagtgac ctttggtcgc ccagaaatca
     6781 agccacattt ggcgtacttg tgcactagat agttgtttca tattgtctcc ttattcactt
     6841 gtttaatgtg attggctttc cagcatttcc acatagtcaa tcgcgacaca gagggaaatg
     6901 actaggtctg cataagcgtc ttcaagaacc gttacggtat aggtagaggt cagatggaag
     6961 agttccttct taatttccgc aatcaactga tcgcgatcat ccagcaattt gaaattcaaa
     7021 tcccagatat tgccctcgat acgaagacct agattatcaa actcatactt atctcgccag
     7081 aaggtcaact tcttacgaat gacaaaactc gagccatccc gaagctgaat ctcaaaacga
     7141 ggaagcaagg tcaagatttc tttactaatc tcactgactt gttcaccagc cgcatcatag
     7201 atggtaaagg ttttaggaat cttaaaaaat gatccctcca cctgataggc aatttctccc
     7261 ctgtcattct tgatagcgaa gcgttcgcct ccaagacgaa acttttgttt gacaagaaat
     7321 gttttcatca acacctccaa aaatcaaaag acaagctcat atcacgaagg gcgaaaaacc
     7381 gcggtaccac cttcattcaa tgaacttgtc attctcttgt tcttatgcaa ttgtatgatt
     7441 gagtagcatg acttcctagc ttagatggct cgcagcaccg ccatttctct ggactaagac
     7501 aagtgaaaat caattctcaa ctttcttatt atatcgtttt tttaatcttg cgtcaactgg
     7561 aaatgatctc cgttgaatta gaccaattcc ctacatctct gattactttt tcaggatata
     7621 ttttttctta ctgccatttt tctttttatc ccaaattttc atattactaa acacagctac
     7681 tagaatattt ccaaatataa aggtgcctat cacccaatat atggactcag ttgttaggta
     7741 ttgtcgatcc aagccatcct ttaaatggaa tagtataaca gtttggttaa caatcataaa
     7801 ggttggccag aaactttttt tgaaaaaagt agacattttc attatttgtt gccgctttct
     7861 gtaaggttaa tactcaataa aaatcaaaaa gcaaactagg aagctagcct caagctgtac
     7921 ttgagtacgg caaggcaacg ctgacgtggt ttgaagagta taggcttagt atactactag
     7981 gcaagcaaat aagcaaataa acaaataaac aactagaata gaaaaagata gggctctaaa
     8041 aactgacttc tattccttaa aaacgaacca gcttgactga ttcgtcttct tacgtttatc
     8101 tcctacttcc gatacatttt aaactgtagg aagaggtcgc tatatttccc tgtccattta
     8161 tggtcaaatt tctcataaac ttctaggtgt ttcatggttt caacatcggg atagaaggcc
     8221 ttatcttcct ttgtttcctc tgggagcaat tccttcgctg gtaggtttgg tgttgaatag
     8281 ccgacatact ccgcattttg gagagcattt tcaggtttca acataaagtt gataaaggca
     8341 taggctgagt tttggttttt aactgttttg ggaatgacca tattgtcaaa ccaaagattg
     8401 ctggcctctg tcggtaccac ataacgtaga ttttcatttt tttctaacat ttggctggct
     8461 tcaccagaga aggtcacgcc gattgcaaca ttattctgaa tcatatagcc cttcatctcg
     8521 tccgcaacga tagccttgat atttggagtc agtttgtaga gcttatccac tgtctcttcc
     8581 aactgctgca gatccttgga gttgaggctg tagccgaggg aattgagtcc tagtcccagc
     8641 acctcacgcg ccccatcaaa gagcatgata gaattcttat actccggctt ccaaaggtca
     8701 tcccaatgct caggcgcttc atctaccatg gtttcgttgt agacaattcc taaggttccc
     8761 cagaagtaag ggatggagaa tttattacct gggtcaaagg actggttgag aaactctggt
     8821 ccgatatttt cgattccttt aatttttgaa taatcaagcg gaaccaagag gtcttcgtcc
     8881 ttcatcttgt taatcatgta ttcacttgga atggcaatat cgtaggtcgt tccaccctgc
     8941 tttatcttag tgtacatggc ttcgttggag tcaaaagtct cgtactgaac ttgaattcct
     9001 gtttcttctg taaactgagt caagagttca ggatcgatat agtctcccca gttatagata
     9061 accaattttt gactatctcg actattgatt ttactatcta aatgagtcgc aattccccac
     9121 aagacaagga taatcgctgc aattcctgct aaaaatgaat agattttttt catgcttgct
     9181 cctccttctc acgagagata aagtaataac ctacaactag gataatacta aagagaaaga
     9241 ctagagcaga cagggcattg atttctaagg aaatcccctt gcgagcacga gagtaaatct
     9301 cgactgatag ggttgaaaag ccatttcctg ttacaaagaa ggtcacggca aaatcatcca
     9361 gcgaataggt gaaggccatg aagtaacctg caatgataga cggagtcagg taaggaagca
     9421 tgatttcctt aaacatctga aattgactag ctcccaagtc ataggccgca tgaatcatgt
     9481 cgccattcat ttccttgagt cgaggcaaga ccatcaagac cacgatagga atggagaagg
     9541 ccacgtgact agatagaacg gtcaaaaagc caagtgaaaa cttgagttgg gtaaagagaa
     9601 tcaagaagct agcaccaatc ataacgtcag gcgcaaccat gaggatatta ttgagtgata
     9661 gaaaggcttc ttggtatttc ttacgagact ggtagatgta aatggcacca aaagtcccga
     9721 taatggtcgc tatcaaggct gataggaagg ccaagaaaaa tgtctgagcc aaaatcagca
     9781 tgagtctccc atctccaaac atggtttcaa agtgagtcca gctaaaacct gtaaagctat
     9841 tcatatcatc accagcatta aaggcatagc caatcaagta aaaaatcggc aggtagagga
     9901 ccagaaagac cagtcccaga taaaggttgg caaatttttt catcgttctc tcctttcctt
     9961 ggtcacccac atggtgatga acatggtcag gatgagaatc acaccgatgg ttgaacccat
    10021 accatagttg tcattggtta gaaaattctg ctcaatagcc gtccccaagg tgataacgcg
    10081 gttcccacca atcaaacggg tcagcatgaa gagactcaaa cttgggataa agaccgactg
    10141 aaccccactt cgcacaccgt tcatagatag agggaagatg acatgacgga aggtctccca
    10201 cttagttgca ccaaggtcgt aactagcatt gatgagatta ttatccatat cgtctaagac
    10261 attgaaaatc ggcaaaatca taaaggggag ctcgatgtag cttgcgacaa agataaagga
    10321 aaaatcggta aaaagcaact gttgtgaacc aattccgata aattccaaga attggttaat
    10381 agagccattt tgaccaaaaa tcccgataaa agcataggct ttaaggagca aattgatcca
    10441 ggtaggaagg ataatcagca tgagccagag ttgacggtgc ttgagacggg tcaaaaagag
    10501 ggctgttgga tagctgataa gcaaggtcac aaaggtcaca atccctgcat aaagcactga
    10561 gttgaaactc attttgaggt aggtcaagtt ttgtgacgca aagtaagatt tataattttc
    10621 taaactaaac tggccttcaa tgttgaaaaa ggattgtccg aaaatcaaga ccaagggtgc
    10681 caatacaaag agggcaatcc aaagcatgta gggcactaca aagagtttag agcttgtttt
    10741 cttcatctct ttcctcctcg atcgcattga tcagacctgc ttcttgctct tcgatttcca
    10801 cgtattcttc gatacgagca tcgaactctt cttcggtttc attgagacgc atgatgtgga
    10861 tgtcttctga ttcaaagtcc agaccgattt cctcacccac gatggcctta cgggttgagt
    10921 ggatcatcca ttcatttcca agttcgtcat aggcgataat ttcataatga actccacgga
    10981 agagctgggt gtcgacctta acttggagtt tgccttcttc aggaagggta atgcgcaagt
    11041 cctctggacg aataacgacc tcaacaggtt catttggctt catcccacca tcaaccgctt
    11101 caaagcgttt gccgttaaat tcgaccaagt agtcctcaat catggtacct ggcaagatgt
    11161 ttgactcccc gataaaggtg gcaacaaagt ggttgattgg ctcatcgtag atgtccacag
    11221 gggttccaga ctggacaatc tcgccatcat tcataacgaa aatccagtca ctcatggcaa
    11281 gagcttcttc ctgatcgtga gtgacaaaga caaaggtaat gcccaatcgt tgttgtaatt
    11341 cacgcaattc gtactgcatg tctgttctca atttcaagtc cagcgctgat aaaggctcgt
    11401 ccaacaagac cacacggggt tggttgatga tagcacgggc gatggccaca cgctgacgtt
    11461 gtcctccaga aagtttgcgg atggaacgtt tttcataacc ttccaactga accatcttga
    11521 gaacttccgc tacacgctgc tcgatttctt tcttatcaat tttacgcaag cgaagtggaa
    11581 aggcaacatt ttcaaacaca ttcatatgtg ggaacaaggc ataggattgg aagacggtat
    11641 gtacgtcgcg cttgttggtt ggaatatcat tgatacgaac accgtctagc atgatatctc
    11701 ctgtcgtcgc atccagtaaa cctgcaataa tgtttaggat agttgatttc cccgaaccag
    11761 atgcacctag aagggtgtag aatttccctt cttccaactc aaagttgatg tctttgagaa
    11821 ccttggtgtt gctgtcttca aaaactttag agacgttttt gaattcgata attggttttt
    11881 tcaattggca taaattcctt ctttttcata gattaaccga tcggggctct gtcaggtccc
    11941 cactacctct tgcagggagt aaaaccacct gcatacatct tcgctaccga taggctttca
    12001 ccccctttcc atgacatagc agcagctttt caaatacagc ttcctacttg ctttcaccca
    12061 agatccggac ttctctttca agcgtaatac ctgagtgttc cttgactttt tcgataaccg
    12121 attggatcaa gtcctcgtag tctttggccg ttccatctgc gacattgatc ataaatcctg
    12181 catgcttttc tgacacttct acgccaccga tacgatagcc tttcaagcca gcttctgaaa
    12241 ttaactgacc tgcaaaatgc ccgactggac gcttaaagac cgagccacaa gatgggtatt
    12301 ccaaaggttg cttgagttca cgtaggtgcg tcaagcggtc catttcctgc ttgataacct
    12361 gatgggttcc tggggctagg gcaaatttaa ctgacaagac aactgcacca gactcctgaa
    12421 tagctgaatg gcggtaacca aaagccaagt ctttagcaga cagggtttcg atttctccat
    12481 ccttggtcaa gaccttacaa gactgcaaga tgtgagcaat ctcgccacca taggcacccg
    12541 cattcataaa gacagcaccg ccaacgcttc ctggaatacc acaagcaaac tcaaagccag
    12601 tcaaactatg acggagggca atgcgagttg tttcaatcaa gttagcccca gcttctgctt
    12661 caatggtata gccatcaaca gaaacgttat tgagcttgtc acacaagatg acaaatccac
    12721 gaatcccacc atcacgaacg atgatattgc ttgcattgcc aagaaccatc caagggatat
    12781 tttcttggtt ggcaaatttc acaaggcgcg ccaactcaaa acgatttcgt ggaaagacca
    12841 aataatcagc ctctccacct acttttgtat aactatagct atgcaagggt tccttaaaac
    12901 ggatatcaat tccttctaag atttcaagca ttttttctct tacagacatg tcactcttcc
    12961 ttttacaaaa ttcattccat tataccattt ttagagacat ttgacgacca taaaaatacc
    13021 ttgtttggat tttgcataag aaaaagaggt tccccccttt ttatgatttt ttacaaaaga
    13081 tttccttggt tccataggcg accagaacga gctccagtgc tagaatcact tcaaccaaga
    13141 ctggatttgt caaccagcct acttggaaaa gagatggtgc cagatcaaag aaggcatgca
    13201 agccataggc tgctaggaga taaatccatt tcttctggcg aacagcttgg taaacccaaa
    13261 ctgtcaaaag taattggaaa ccaagcgcca agattcgctc aaaaccaagc aaataaatct
    13321 gccagaccga aagtgactga atggttttta acatattttc agacagtaat tgcataacct
    13381 gtggattctg agtttgaact gccgaaagaa cgatgtaaag attgagtaaa ctaataaggc
    13441 ctagaaaaat caactccaag ccaccatgcc ctaggccata ggccaaggca tctgcctttt
    13501 ccaaacttct ctttttctcc aaccatttga agaaaacaag acgagccgtt tcctcaaaaa
    13561 atgctgccat ggctaggcca tagataatat agataagcgg atgatcttgc aagagggcaa
    13621 tactaccgtc tttttgaggg tgcaaaatca agatatgcac cagtttttcc aaaatctgcg
    13681 aagagacaaa gaaagcgact gcacccaagc ccaagacagc tagattaatc tggtatttct
    13741 ttttggcaaa ccaaatgctt cctatcagaa aagctagcaa cagcaacatg gtaataatga
    13801 tatgaatggt cattttcttc tcctattctg ccttttcaat atcttttttc atctcgtcaa
    13861 cattgaactt agcaaacaag tattgacggt cttggactgg gaaacgttgg tccaactggt
    13921 caactgctcc cacctcgata atgccttcct tgatgacaaa atccatgaca tgtccaccga
    13981 aggtcaaatc atctgatatg aagtgcagat ggtagcctgc cacactgacc ccatggaaaa
    14041 tctcaggcgt ccagaaacca acaatagtcc ccgcaacatt gtcacgacta tattccggtt
    14101 gatgggttgc gacatcagca aacttagtat cgggtgttga cttaggaatc atacgcacat
    14161 gcatatgtga aaattctccc cgaatcttga tagaacggaa aagattttcc ccatcataat
    14221 aagactcaat tcgttctttc aattccttgt ctgtcatctc aaagcgctgg cggaaaatga
    14281 cctctgcctg atgcggtacc actgcagcgt aaggaataag ggcatctggt gacacttcca
    14341 caatttctgg ctggtctcct gaccctttgg cctgataagc cttgccatcc aagacaatca
    14401 attccccatc aatagaatcc aaggttccca aaccaaggtc accatgctct agcaattctc
    14461 ccactgtcat ggtaccacca taaaggccag ccatcaaggc tccaagagta ttgtattgaa
    14521 ataatttcac tggttcctgc acgttcttat ccattcactt tcttgtctgt tattctataa
    14581 atcttactcc taagtatacc acatttgccc ctagatgtga acgagagaaa cgctctagac
    14641 attgccaaga aggaaaaaaa agggtacaat gtaacaaaat caagggaggt ctggaatgaa
    14701 gaaacaaagc aagtacaaag aggtcgtttc ctatctgaaa aatggtatcg agtctggacg
    14761 atttccgacg ggtagtcgcc tgccttctat ccgtcaactg agccttgact ttcactgtag
    14821 caaggacacc attcaacgag ccctgctgga attacggcac gaacaatacc tctatgccaa
    14881 gccccagagt ggctactatg tcctagaaca agggcaacac caggacctag aaatcgaggt
    14941 taccgacgaa catgccagtg cctatgacga tttccgactc tgtgtcaatg aaaccttgat
    15001 tggccgagaa aactacctct tcaactacta tgataatcaa gaaggattag aagacctaag
    15061 acaatccatt cacaaactcc tctttgagca agctctctac tgcaaggcta accaactagt
    15121 actgacttct ggaacccaac aagccttgtt tatcctctct caaatatcct ttcctagcca
    15181 agccaaggaa atcttggtgg aacagccaac ctaccatcgg atgaatcgcc tcttgattgc
    15241 acaggggctg gactatcaaa cgattgaacg aggcattgat gggattgacc tgaaggagct
    15301 ggagcgacac ttcaagacag gaaaaattaa gtttttctac accattcccc gatttcacta
    15361 tcctctggga cattcctatt ctgagcaaga caaacgatcc attcttaact tagctgccaa
    15421 gtatgatgtc tatatcgtag aagacgatta tctgggtgat ttggactcca agaagggcca
    15481 aaccttccac tatcttgata cagaggagca tgtcatttat atcaagtcct tctcgaccag
    15541 cctttttcct gcccttcgta ttacagcact cattcttcca aatgctatca aagaagcatt
    15601 tgtggcctac aaaaatatcc tagactacga cagcaacctc attatgcaaa aggccctgtc
    15661 actctatatt gacagtcaat tgtttgaaaa aaatcgtttg gctcgcttga ccaatcatga
    15721 atcttaccaa aaacaaatcg aggaaaggat aactaaaaca ccttgtcccc ttcctcatta
    15781 tcccctacac gatggtttat tgctagacct gagacagtat cctaaaatcg ccagtctcaa
    15841 acacagtcaa ccgggcttgg acttctttga agaggcctat ttaagtacct gtccttatca
    15901 atttgccaag gtgtccctag acaatctgga aaatgtttta aactatttaa aagcagaatt
    15961 ggaatgacat ccaactctgc tttttcttat tcttcaactt cagttagact tgctgctttt
    16021 tcaagatagc tttggtaaat tccttcatcc ttaagttttt ggatgacctt gtctaccact
    16081 tctttcaaat catcactatt ttttctaaga gcaacggcat tggcgtcgcc gtccttcatc
    16141 ttcaagctga cagttgcgac agctaagcca gcgtttttag cagcataact aagtgcaaca
    16201 ggctcatcca tatgaacagc atctactttt ccagcctgca attcattgac tgcttcaccc
    16261 atattagtta gggaagttaa ttgagctttt ggcaattgtt ccttgaccat tgattctgga
    16321 acagtccctt tttgggctgc aatattagca ctttctaggc tagttaaatc cttgtatttt
    16381 tccacatcag ccttacgaac caagaaacta atcttgtttt catagtatgg gattgaaaaa
    16441 tcaaagactt cttttctctc gtcagtagca ctaattcctg caactgctag gtcagcctta
    16501 ccagtttgaa gactggtcaa aacattgtca aaactcatgc ttgagatttc caacttaacc
    16561 ccaagttcat cagcgatagc ctgagccatg tcgatgtctg caccgactac ctggttcttt
    16621 ccatcaacca atgattgaaa ttcaaagggt gcatagtcag gactggttgc cacaactaat
    16681 ttcccctttt gcttaattgc ctcaacagct gactgagaac cattagaacc tgactggcaa
    16741 gctactaaga agaaacttgc aagaaaatta cataaaacaa atatccattt ttttgatttc
    16801 ataaataaac aacctctctg ttaattttgt ataattataa cgatatccaa gttacttgtc
    16861 aagtgttttt taaattttta tctcaaaaat attttttcgt tcaaaaaaag gagccatcag
    16921 ttgatttcaa gctccttttt atacagaatt aaactatttt atagttcgac aatcttacct
    16981 gtttcaaagt agacaaccca ttcacagata tttttagcat agtcaccgat acgctccaag
    17041 taggaaataa cttggaaata atcacgaccc gtaacaatgg cttctggatt tttcttaatc
    17101 tcttcagtcg caaggtcacg gatagtttca aaatagtggt taatttgctc atccatggag
    17161 gccacccggt atgcgtcgtc aacagaacca ttaagataaa gatcaagtgc tgcttcaaca
    17221 acgcttttaa cttcacgtcc cattttttta atttcttcct ctacagctgg aatacgttct
    17281 tcccccttca tacggatggt tgcctgggca atggctacag cgtgatcccc catacgctcc
    17341 acatctgata cagccttaag gacagtcaag actgtacgca aatcttgaga gactggttgt
    17401 tggagtgcga tcatttcaaa tgatttcttt tccagtttca cttcgtattc atttacttct
    17461 gcatcatctt cgatgacctc ttttgccagg tcacggtcat gcgtgacaaa agcacgtacc
    17521 gtacgattga tttgtgagag cacttcttgt cccatagcgt agaactggtt atgtaatttc
    17581 tctaaatctt cttcaaattg agatcgtaac atctttcatc tccttatcca aattttcctg
    17641 taatatagtc ttccgtttcc ttgtgttggg gatcaaggaa catctgcttg gtatcattaa
    17701 attcaatcaa atctccatct aggaaaaatc ctgtcttatc agagatacgt gaagcttgct
    17761 gcatggaacg ggttaccaga agcatggtgt acttgtcttt tagaccatac aaggtttcct
    17821 caattttacc agctgaaatc ggatccaaag ccgaagttgg ctcatccaag aggatgattt
    17881 taggactagt tgccaagaca cgggccacgc agacacgctg ctgttgacca cctgacaatc
    17941 caatagctga atcatataga cgatccttga cctcatccca gatagaggca ccttgcaagg
    18001 ctttttctac ggcttcatcc agaacctgct tatccttaat tccattgata cgaagcccgt
    18061 agacaacatt ctcatagata gtcataggga aaggattagg ttgttggaaa accattccga
    18121 tttccttacg taattcaacc gtatctgtac gcggactgta gatgttgtga ccattgtaca
    18181 ccacggatcc agttgtggtc acctctggat tgagatctcc catgcggttg agagacttga
    18241 ggagggttga cttccctgat ccagatggac caatcaaggc tgtaatttcc ttaggttgga
    18301 aagataggga aacactattc aaagccttct ttttattata ataaacggac aggtctgata
    18361 cctgtaaaat cgcatctgtc atacggtttc ctttctaacc aaagtgacca gatacatagt
    18421 cattggtgga ctgtagcttg gcattttgga aaatagttgc agtcttgtca tactcaatca
    18481 aatcacccaa gtaaaagaag cctgtatagt cacttgcacg agcagcctgc tgcatattat
    18541 gcgttacaat gatgatggta aagtttttct tgagctcaaa catggtctct tctagttgca
    18601 tggtcgcaat cggatccaag gctgaggctg gctcatccat taagaggata tctggcttaa
    18661 cagagatggc acgagcgata cagagacgtt gttgctgacc acctgataag gtcaaggctg
    18721 acttgtggag atcgtcttta acctgatccc agagggcagc ctgacgaagg gaggtttcta
    18781 cgatttcatc taggacttgc ttatccttaa ctccagcacg ttcatgcgca aaggtaatat
    18841 tacggtaaat tgacttagca aatggattgg ggcgttgaaa aaccattcca atgtgtttac
    18901 gcatttcata aacgttgatt tctggacggt tgacatcaat tccacgatag agaatctgcc
    18961 cagttacttt agcaatatca atggtatcat tcatgcgatt gagactgcgt aagtaggtag
    19021 atttccccga tcccgacgga ccaatcaaag ctgtaatttt atttctttca aattgcatat
    19081 caatcccctt aatggattca tttttaccat agtaaacatg gacatcctta gtagaaaggg
    19141 ctactttttc ttcaggaaag gtaaggatat gcttctcatc ccagttatat gttgacatgg
    19201 cttctccttt aggcagcggt taatttcttg tgtagatagc ttccgaactt acgagctcca
    19261 aagttaaaaa tcaggataaa gatcaggagc acagcggcag aacctgctga tacaatggtt
    19321 ccatctggaa tagtgccttc actattgact ttccagatat ggacagccaa ggtttctgct
    19381 tgacggaaga tagagatggg gctagtcaca ctgaggatat tccagttaga ccagtcaaga
    19441 gctggcgccg attgccctgc tgtatagatc agagctgcag cttcgccaaa gatacgacca
    19501 gatgccaaga cgacacccgt tacaatacct ggaagcgctt ctggaataac aacatgaacc
    19561 actgtctccc agcgagaaat cccaagagcc agaccagcct cacgttgggt atggtgaacg
    19621 tgtttcaaac tatcctctac attacgcgtc atctgaggca agttaaagac tgtcaaggcc
    19681 aaggcacctg aaatgattga aaacccatac tcaaactgga ctacaaagat caagtaacca
    19741 aagagaccca ccaccactga tggtaaagag gacaagattt caatacaagt ccgcacaaag
    19801 ttggtaacag gacctttttt agcatattca gccaagtaaa tcccagctcc catagaaaga
    19861 ggtacagaaa taatcaaggt aatgaccaat aggaaaaagg aattgtaaag ctgaatgcca
    19921 atcccaccac ctgcttgaaa agcagaagac cttccagtca agaaagacca agagatatgg
    19981 ggcaagcccc gaaccaagat atagagaatt aaggaagcca agattgtcac aatgatgcta
    20041 gcaatcgtat agaggacagc tgttgcaagt ttatctaatt tcttagcgcg cataattttt
    20101 ctttcctctt tctttcgtaa tcaatttaat cacactgtta aaaactaaac tcatcaagag
    20161 cagtaccaag gccagtgacc agagaacatt attatttaca gttcccatga cagtgttccc
    20221 aattcccata gttaatatag aagttaaagt tgcagctggt gtggtcaagg aagttgggat
    20281 aacagctgag tttccgacaa ccatctggat agctaaagcc tcaccaaagg cacgcgccat
    20341 cccaaagacc actgcagtga aaataccaga acgggccgcc ttcaagatca cacgccagat
    20401 agtctgccag cgagtggctc ccatagcgaa actggcctca cgataataac gaggaaccgc
    20461 acgcaagcta tccgttgtca taaaggttac ggtcggcaaa atcatgacaa agaggacgga
    20521 aatccctgac aaaatcccaa aaccagtccc accaaagaca ctgcgaacaa agggaacgac
    20581 gacttgcaag ccaataaatc cgtacactac tgaaggaatc ccaaccagga gttcaatagc
    20641 tggttgcaaa atcttcgccc cttttggtga tacttcggtc ataaaaactg ctgcaccaat
    20701 agcaaagggt gttgcgataa gggctgagag aatggtaacg ataaaggaac ccaaaatcat
    20761 aggaagggca ccaaattctt tactagaagg attccaagtt cctcccaaaa gaaagtcaaa
    20821 gatattcaca ccattgacaa agaaggtcga caagcctttt tgcgctacga aaaccaaaat
    20881 catggccaca aggatgacta tcaaagaaag acaggcaaag gtcaaacctt ttcctaattt
    20941 ctccagacga gaattctttg atggaagcaa cattttctta gctaattctt cttgattcat
    21001 tattgtctcc cttccaacac tgtcacagtt ccggcagcat ctttttcaac cttcatttcc
    21061 ttaatcggaa tatacttcaa tcctttgaca atcccttctt gggtctcatc cgagagaaca
    21121 aaattgagaa attctgcagc caactcattg ggctgcccca atgtatacat atgctcataa
    21181 gaccacaagg gccaattatt gctacttata ttttctggac ttaagtcata gccattcaac
    21241 ttcatgcttt tgaccgaatc atctatatag gtaagagata aataagagat agctcctgga
    21301 ctttttgata cgattgattt taccgctcca tttgaatcct gctcctgact ttgcatggca
    21361 gactgacctt ccataatgac agtatcaaag gtagcacgag aaccagagcc ggctgcccga
    21421 ttgataacag agatgggtaa gtccttacca ccaacctctt tccaattggt tacctcacct
    21481 atgaagattt gacgaagttg ctctgtcgtt aggttatcaa catcaacctc cttattgaca
    21541 atcagagcca agccagctac cgcgaccttg tggtcaacaa gagcagaagc atcaattccg
    21601 tctttttcct cagcaaatac atctgagttt cctatatcaa ctgccccaga ctgaacctgg
    21661 gacaagcctg taccagaacc tcccccttgg acattgaccg tttttccaac atggatcgtg
    21721 ccaaattcat ctgccgctac ttcaaccaag ggttgcaagg cagttgagcc aacagccgtt
    21781 atggattctc cacgatcaat ccagctagca cagcctacta aacaagccgt cagccaaaaa
    21841 gcgataagag acagagcaag cttttttctt tttttcactg tttttctcct cgaaaataat
    21901 tatgaatact gtgaattttt taagtagttc tttatgagtt gacgcatgaa ttcttaccaa
    21961 atttctgcgc aattgattat ttatataata taggctatat tactctttcc taacctcctt
    22021 ttttcatatg tggataaaat ctcttgtcta tcccttcccc cattgtcacc cattatagtc
    22081 atttcgtgtc tctttttccc ctttttaatg caagggaaat tactctcctt agatgataat
    22141 ccaaaagcta gaaaggtatc tcaaacctct ctactctccc agactagttt acaactaaaa
    22201 ggaaaagatt ctattttatg agaaatctag tttacaagcg gtaagaacgc taataactaa
    22261 acttcttgta ctctttgaaa atctcttcaa accagtgttt tgagctatct atggctagct
    22321 tcctagtttg ctctttgatt ttcattgagt agtaaaacta catgtaatgg caatcaagat
    22381 atcaagaatc atcctactaa aaaaatccat actttcacta taacatagaa taagatattt
    22441 gactagcatt ttcatttgaa tctgaggcct tttggaaaat aatttttcaa aacatttcca
    22501 gtaacctttg caaagcccaa gccattgcct ttaaccaaaa cttggtacca accatttggc
    22561 agactttctg ccagctgaac gatttctcca gccgcatact tgacaaacgc ttcttggcca
    22621 atttcaaccg actgttcgac ctgactcggt ttcaaggcta aaccaagagc gaaactgggc
    22681 tcaaagcgtt tcttcttaaa agtgcccaga tgcagtccat tgcgagcaat cttgagcttc
    22741 cctaaatctg gcaaaagttc tggcaagaga taaagctggt ctccaaaagt ctgcaagata
    22801 cccggtagat tgaccttcaa atggttttgg gcaaattcct gccacaaggc aacttgttca
    22861 cggctgaggt tactcttact tgccttaaat ttaggagctg gattgttacc cttaaactgt
    22921 agatgggcaa caaactgacc ctctccctta aactgatgag ggtacatccg agccgtttct
    22981 ggcaggtcaa taccagctac cattccattg atatgctcta ctggcaacaa gtcaaaatca
    23041 tactcttcca gcaaccaatt gacaatctct tcgttttcct cgggtgccca ggtacaggtc
    23101 gaataaacca gacgaccacc ttcagctaac atggtcactg catcctccag aatttctctt
    23161 tgcaagctag cacattgact cggataatct aagctccaat agtccatagc atcaggttgc
    23221 ttacgaaaca ttccttcacc agagcaaggg gcatcaagaa cgattaagtc aaaatagcct
    23281 ttaaagacct tgaccaagcg gtcggcagat tcattggtca ccacgacatt tgtcgctcca
    23341 aaacgctcca tgttttcaac caaaatctta gcccgtttgc ttgaaatttc attggaaaca
    23401 agtagcccct cccctgctag ataggctgcc agttgagttg atttgccccc cggtgcagca
    23461 gccaagtcca agaccttcat accaggactg ggttgagcta cttgagccac catttgagca
    23521 gcaggttctt gcgaataaac taaacctgta gcatgctcag gcgatttccc tgaaaccttc
    23581 ccatagtggc cccaaggggt ttgagtaatg gcatcagaaa aggaaagttg ctcttctttt
    23641 aagggattga cccgaaaggc cgaaaccgct tcctcctcaa aagaggcaag aaaatctctt
    23701 gcctcatctc ctagtatctc tttatatttt tcaacaaatc cttctggaaa ttgcatttaa
    23761 gttcttttcc tttcgtaaat ataggactga atttcctcct gcatctcaag aggcaccatc
    23821 atgaccggct gtctggtttg aaaatcagga gcttcaccaa aaagggtcac aacccgatag
    23881 cccagacttt cccctaaaat actagctgcg gcataatccc atggttgcag ataagtgaga
    23941 taggtcaaca aacgccctga caaaatcttg gcaaaactaa tggccgcact tccatagaca
    24001 cgaacaccaa gaaccgctcg gctcaaatca gccagccccc attcattggt ttccagcata
    24061 ccactattcc ctgcaatgag aaaatctcca agtggtttag ttttaaaagg agctaggggc
    24121 ctatcattta gacaaactgg aaattcccca ccaccgtggt aacaatcccc tttgaccaca
    24181 tcataaatca gaccaaactg tccctgacca ttttcaaaat aagccatcat aacagcaaaa
    24241 tcttcctgct gggctacaaa attattggta ccatcaatgg gatcaatgac ccaaaccttg
    24301 ccctcttgaa ccgaggctcg cagacaacct tcttcagcac aaatcttatc ctcaggataa
    24361 cgggacaaaa tctcaccaac caagagttcc tgaacttctt tgtccagtct ggtcaccaaa
    24421 tctgttggag aggacttggt ttcaacacgc aagtcttcct gcatatggtc aagaatgtac
    24481 tgacctgctt tcttaacaag ctctttagca aattcaaatt tactttccaa gagaaatctt
    24541 tccttcccct ttttctttgg cagcctgaac tgctcggtaa agtgaatagc cactaaccgt
    24601 ttcaaattct cgtcccaaac gtttctcttc gctcttgctt ggcacgaccg ctttgaatcc
    24661 cttataggag tccagtaact ttttagcctc tactttgcct tcataggcag cttcaacatc
    24721 attaaaaaaa gaaagcactg aagcaagttc ttcagtgctc cacgacaaat ctagtgggta
    24781 actatactgt ttgttcatta actaatacca gctctcattc ttgcttcttt tagttcttgc
    24841 ttacgataac tacgagggag aaaagcacga atctcatctt cattaaaacc gatttgcata
    24901 cgcttggcat caataataat tggacgacgc aaaagactag gatactgctc aatcaaatga
    24961 agcaattccg ataccgaaat actctctaca tcaatattca atttttgaaa aatttttgaa
    25021 cgagttgaaa tgatgtcatc agtaccattt tcggtcaagg aaaggatgtg ttgcaattct
    25081 tttcttgtta aaggactggt cataatattg tgttccacaa agggaacctt atgtttttct
    25141 aaccaggcct tagccttacg acatgatgta cagctcggtg atagaaatag tgtaatcatg
    25201 cttttctctt cttatctata ctttgctact tctattatac aaaaaaataa ggcgcttgac
    25261 tagggatttt tagaaaaaaa gcctattttt tcaagaaaaa taggctgttt gcgaacgatt
    25321 gacacaattg gatttggtta attcactctt aacgatggtt ttaaacgata tatattttta
    25381 tatatgcaaa ttaaaaacat ctttcatttc acttcctacg acttttcaga cacagatagc
    25441 caaagaagct ttcatagagg gcaaaaaaga ggaggaaggc atgaagaaag aaggtctctg
    25501 gcaaaatcat aataacagga tccttggctg gatcaaaaag ccaggtatca tctcccacaa
    25561 agagaatttg atggaaaaga gtaaagaatt ggtcaaaacc aatcaaaact cccccaagtc
    25621 caatcatcac aggtaagact actagagcca ggagactttt tcgataaaga gacaaaaagt
    25681 cctttttcac aatcctattg acaaagacat agaaacttgg cagtgtcact agagctacta
    25741 gctgaaccaa atgaaagaga ttcttgacca ctgcgaaatg gtgcagacca gctgctgacg
    25801 aacgaaaatc aggcatctgt aagacctgac taaaaggatt ggtcagataa ttcatcaaga
    25861 tatgaaaatt gtattgaatg gtttctggtt ttagatagac tcgattcgtt aagtttagcc
    25921 actgaatctc cataggatag aaaatccaag ccagataaat ggtcagaagg attgagaggg
    25981 agaggagaaa gagcatagag ccccaaaagg tcaatttagt tttcatcaaa atcccactcc
    26041 gcaaggctag aaaccacatg tgtcggtgcg attggcaggc cagctacttc ttctgccttg
    26101 gtaaaacctg tcgtcaccaa gagcgttgga atgccattgt caatcccagc ccggatatca
    26161 gtcaaataat tgtccccaac catgattaac tcttcacgtt ccaaacctaa gtgctcaacc
    26221 gccttgtcca taatgatggc atttggtttt ccgatataaa ccggcttcac tcgtgtcgct
    26281 acttcaagca gcgtaatcag tgagccagca cctggcaaaa gaccgcgttc cgtcgggatg
    26341 ttgaggtcag gattggttcc gataaaatgg gcaccctttt gaatagcaag agttgctgtg
    26401 gcaaattttt catagtcgac ttgccaatcc agaccaacta ccacgtaggc aggtttttcc
    26461 ttgtcttcca cataaccagc cgccttgatg gcttccttga gtcctgcttc tccgacgaca
    26521 tagacggtct tttcaagccc caaatcattc atatagtcga tggttgccaa agtcgctgtg
    26581 tagacagtcg ataggggcgt atcgatatta aaattctgag ccaacatctc cttaacactc
    26641 tctggagtgc gggttgtatt gttggttaca aagagatagg gaatgtcccg cttttgcaat
    26701 tcatgaacaa aagtctctcc agcagggatt cggtctttcc ccttataaat ggttccgtct
    26761 aaatcaatta aatagccttt atatttcatc tatttctccc taagcctttt ttatttcttg
    26821 ccaagtaatg attgcttggg cattgataac cccatcactt gtaatttcat gcttgctttc
    26881 cagtccagtc cgttcaacag ccgatgtaat caccccacct ggtcgaactt ccttgacata
    26941 cttgaggttg attttcttgg gaatatagtg ggtcaaaaaa tccgctccca tgacctcaaa
    27001 aatccagtcc aagtatttac tgttattgac atgaccattc atatccaagt cgtaaaaacg
    27061 aacatggtaa tccttgctga tcggttcttc caaggactca tacttcggtc cacggataag
    27121 ttttttatca aaatcagact ggtaaggagc cacaatctca ggttcaacaa catggacttt
    27181 tcgactgtcg cggtccatga gaacaaaggt cgccatcatg tggatgagct cctgctccgc
    27241 ttcattataa atagtaaagc gacggtagca aaaaagtcga ttgtagctca aggcttccgt
    27301 ttcgatggta atttcttccg caaaacgagg caaacgaacc acctcaatat catattctac
    27361 gataatccag accagattat attcttccaa aatggcctta tcactaactc ccagttcaat
    27421 cgactgcatc cctgaaactt gcagtgacag caaaatcaca tctggaagtt tgatatgacc
    27481 gttcatatca gccatatcaa aaggaatttt cattttcatt tgataagtta agcccatgat
    27541 cctactccaa aataaatcgt tctgctacag tatctcccaa aaagagacct ctctttgtca
    27601 tgcgaacgtg gtcaccctca atctgcatga ggccttgttg aaccaaatct ctgacaattt
    27661 ctccataaag tccagcaaaa gactgtccaa atttttcctc aaatcgcgcc atggaaaccc
    27721 cggatttctt gcggagtccc aagaacattt cttcttccat ttgctccttt tgactcaggt
    27781 gatcttctgt aatacaagca ttgccttcct caaccgcact gagataatga cgaatgggac
    27841 catgattttt atagcgtact ccattgacat aaccagatgc ccctgcacca ataccatagt
    27901 attcagcatt gtcccagtac atgagattgt gacgactttc aaaaccgggt ttggagaaat
    27961 tagaaatctc ataatgctca aaacccgctc gctccagctc tgcaatgatg tactcaaaca
    28021 tctccgcttc tagttcctcc ttaggcagag gcaatttccc acgtcgcatc cggttcataa
    28081 agaccgtatg gttttctaaa atcaaactat acaaactcat gtggggaata tccagtccaa
    28141 tggctttagc cacattttcc tttacttgct ccatggtctg accaggcaga gcataaatca
    28201 aatcaatgga gatgttgtca aaaccagcca gtttcagacg atcgatattt tcataaatat
    28261 ccttctccaa atgactgcgc ccaatctttt tcaacatctt atcatcaaag gtctggacac
    28321 ctagcgaaac acgattgaca gccgaatttt tcaaaacagc tatcttatcc gcatccaaat
    28381 cgcctggatt ggcttcaatg gtcaactctt ccaagacaga caagtccaag tttttagtca
    28441 agccattcag taacacctcc agttgcggag ccgacagggc tgtcggtgtt ccaccaccga
    28501 tataaagggt tgacaacttt tcaatatcat aagaacgaaa ctcttccagc agatgctcta
    28561 aatagctgtc gactggctga tttttgatga agacctttga aaaatcacaa taataacaaa
    28621 tctgggtaca aaatgggatg tgcacatagg ctgacgttgg ttttttctgc atagtaatta
    28681 ttataccaca aagactagat tccagataaa aatcaccatc cccagataca tagtccgtcc
    28741 ggagatggtg atggtttatt cttctgttat atcaatcaca atctcttctg agtcatcaag
    28801 agcttcggct ttttcttgcc attgttcctt gagattattt aattgatttt ttgatgcttc
    28861 tgtcgcttga aaagcatagg atttagcttg agcaagtata ctgtccacag tgatttcacc
    28921 tgactcaacc tgttcttttg ttttcagaac aaaatctgta gcctgctcct taacttctgt
    28981 cagtttttca cagacttgct ccttggcata ctccggatct tctctcaaat catctagaaa
    29041 atcttgagcc tgactgcaaa cttgtttgcc cttatcactt gttaaaaaca aggcaagagc
    29101 tgcacctgaa accgttccta aaaggattga ggataattta cccataagga ttctcctttt
    29161 ttattttttg aaaaatttac ttgcaagacg aagagctgac agacttgcac cagtcttgag
    29221 tgtttttgaa ccagctgatg aagctttctt gctcaagaca cgcgcatggt cattgaggtc
    29281 tgaaacagat agagataaat ctgcaacagc actgaagagt ggatcaatcg tagccacctt
    29341 gacattgata tcatctgcca agacattgac cttagccaac aactcattgg tgtgatgcaa
    29401 ggtcacatcc acatctgaag tcaaggtttt aatcgtcttt tctgtttcat cgatgacacg
    29461 accaagcttt tgtacagtaa tgatcagata gaccaaaaag acaatcaaag ctagggcaac
    29521 aagaatatat gcaacttcta acatttattt ttcctcctct gtaatatagt aaggggcctt
    29581 ctttcgattt tgataaataa cgatcattat accgagaccg ataaggacaa ctgacagcca
    29641 ttgggacact cgaaggctga agaacatgag actatctgtt cgcatacctt cgatgaccat
    29701 acgaccgaaa ccataccaaa tcaagtaaaa ggccgtgata tgacctcgtc tgagactctt
    29761 ccatttccgt ctaaaaatca gaatcaaagc aaagccaagc agattccata gagactcata
    29821 aaggaaagtc ggttgacggt agctcccctc aatatacatc tggtcacgga taaagccagg
    29881 tagataatcc agattatcca ctgttgcacc ataagcttct tggttaaaga aattacccca
    29941 acgccccaaa ctttgagcaa tcataacgct aggcgccgca atatctagaa aatcccaagt
    30001 attgatgagt ttacggtcag caaagatata gagcacaaga gccccagtta tcaaaccacc
    30061 gtaaatggcc aaaccaccat tccaaatggc aaaaatctct cctaaattct gactatagta
    30121 atcaaatcgg aaaataacat agtagagacg agctcctaaa atagccaagg gaaaggctac
    30181 taagataaaa tctaaaatat cgtctggtat gatcttcttt ctaggtgctt ctttcatggt
    30241 caaataaacc gcaagaatca agcctgtcac aatacataag gcataccaac gaatggctag
    30301 gggtcctagt tgaatagcaa ttggatcaag cattttgcac ctcatttcga gcaatgagac
    30361 ttgtcagtcg ttcgtcgaac aaacgggtcg catcaaagcc catttccttg gcacgataat
    30421 tcatggcagc tgcctcaatc acaacagaga tattacgacc tgttttaact ggaatacgaa
    30481 tacgaggaat ggctacgcca gaaacttcaa gttcctctgc attgtttcca agacgatcaa
    30541 aggtcttatg tgtatcgtaa ttttccaaat agacagcaag ctgaacctgt gaagaatcct
    30601 tgacagcact cgcaccgtag agactcataa catcgataat accaacccca cgaatttcaa
    30661 tcaagtgttt caaaatttca gctggttcac cccagagagt aatctcatcc ttggcaaaga
    30721 tatcgacacg gtcatcggct accaaacggt gaccacgttt gacaagctca agacctgtct
    30781 cgctcttacc aattccacta tctccctgaa tcaagacgcc catcccataa atatccatca
    30841 agacaccgtg cacactggta cgttctgcca aacgagaatc cagatagcta gataactctc
    30901 cagataaacg actggtagct gcacggctgg ttaaaatagc aatcttacat tctctagcag
    30961 cctttaacat ctcctctgga accaccaaac cacgagcaac aatgactgct ggtgtctcag
    31021 gtagaaacat ttttttcaaa acttcataac ggctgttgga aggcatgctg atcagataag
    31081 accactcctt catccccaaa agttgaatcc gctctggtgt atagtagtca aaatagcctg
    31141 tcatttcaag accaggtcgc gtaatatccg ctgtattgat ttccttttca agcaactctg
    31201 gttcaccata gacaatgtct agtctaagct tttcaatcac ttcttttact aaaaccgaca
    31261 tcatttcctc cttcaaatga gttcttctct ctattatatc aaattgtagg aggaagtttc
    31321 agatttttgc aggctttgga gtatttattt aaaagaaaaa ggactagatt tctctagcct
    31381 ttcatttcaa ttagaatttt ttacgtttac gagctacttc tgatttacgt ttacgtttta
    31441 cagaaggttt ttcatagaat tcacgtttgc gtgtttcttg aagagtacca gctttagtaa
    31501 ccgcacgttt gaaacggcga agtgcgtcgt caagagattc attcttacgt actactgttt
    31561 tagacatttt tttcactccc ttcaagttca atatctattt cattctacac gtaaaaggaa
    31621 taattgtcaa gcaaaaatgc ggtttaattt tgattttttc ttccatttat acaagagttg
    31681 aaagcgttca atagaacatt gcttttttat ttttcgagta agctaagcgc ttcagcatct
    31741 gcgatgatgg ttacatcagg gtgattttga aggctacttg caggtaggtt ctcagtcact
    31801 gggccagata ctgttccggc aatggcttct gctttcgact caccgtaagc aaaaagaata
    31861 atagacttgg catccaaaat gtttttaatc cccattgaaa tagcttgggt tgggacgtct
    31921 tcaatcttgg caaagaagcg tgcattggct tcgatagtag actggtcaag ttctactaga
    31981 tgcgtttgac tgtcaaatgg agtaccaggc tcattaaagc cgatatgccc attgcgaccg
    32041 attcccaaga tttggaggtc aactggatgg tcagccaaaa tttggttgta gcgttcaact
    32101 tcagcttcag cattgtcctt aacaccacga ggcaagaaac tttctttaaa tggtttttgg
    32161 ttgaacaagt tttcttgcat gaagtaacga taagattgtg gattgtcccc atcaaggccc
    32221 acatactcat caaggttgac actggttaga tttgaaaaat caaggtcact ctcaacaatt
    32281 tccttgtaaa attcaagtgg gctacttcct gtcgcaagtc ctagagtttg agctccatta
    32341 gccaattttt ccttcaaaat ctcaaaagca acttttccac cttgaacttg gttttcaact
    32401 ttaataactt tcatcttttc atcctccatt tctgtctata tttattatat ggtatagacc
    32461 aatttttgtc aagtgaaaac gatttaattt ctaaaaaaag agcgtccaaa cttgaaacgt
    32521 gttataatgg ataggattag aacttagaaa gaatgaacaa atatatgaat acagctgatt
    32581 ttgatttcca cttgccagag gaattgattg cccaaacgcc ccttgaaaaa cgtgatgcct
    32641 ccaaactcct catcgtcaac cgtgagacag gagaaatgca agataaacac ttctactcta
    32701 ttattgatat gctggaacct ggtgatgccc ttgtcatgaa cgacacccga gttctccctg
    32761 cccgcctcta tggtcaaaaa gtggagacag gaggtcatgt ggaacttctc ctccttaaga
    32821 acactagtgg agacgagtgg gaagttctgg ctaaacctgc caaacgcctc aaggtcggta
    32881 ctcgtatcag ctttggtgat ggccgcctca gcgctgtcgt tacagaagaa ttgacccacg
    32941 ggggacgcat tgtccgcttt gaataccaag gaattttcct agaagtcttg gaaagtctgg
    33001 gagaaatgcc tctgccacct tatatccacg aaaaattaga tgaccgtgaa cgttatcaaa
    33061 ccgtctacgc caaggaaagc ggctctgctg cagcaccgac tgctggtctt cacttcacca
    33121 aagaactgct ggcagaaatc caagctaagg gtgttcatct agtctatctg actctccatg
    33181 tcggactcgg aacctttaga cctgtttctg tggataatct ggacgaacac gaaatgcact
    33241 cagagttcta tcaactttct gaggaagctg ctgccaccct tcgctctgtc aaagaaaatg
    33301 gtggtcgcgt catcgctgtc ggaaccactt ctatccgcac cttggaaact attggttcca
    33361 agtttgatgg gcaaatccaa gcagattctg gttggaccaa tatctttatc aaacctgggt
    33421 atgagtggaa ggtcgtggat gccttctcaa ccaacttcca tctgccaaaa tcaactctgg
    33481 tcatgttggt ttctgccttt gcaggccgtg aattagtctt agatgcctac caccatgcca
    33541 tccaagaaca ctaccgcttc ttcagttttg gtgacgccat gtttatttat tgagaaagaa
    33601 tttctctaat tcttctaata ccaataaatc gctaagatat tatttcaaag aacatctaca
    33661 attgaaactc tagctagctg tagaagacgc ctagtacatt gaaattaaaa tgcttccccc
    33721 tagcttcgaa aatattgcca tagattgcgt tgactctcca aattgattca tctatatttt
    33781 atttcagctt cctatatttt cttcgctgtt tgtaaatcaa aatgcaagac acatgagtag
    33841 caccatattt gttactctta tctgtcctct caagagacta ttatgagtta tttcagaatc
    33901 attcactact ttgaccctga ctctccttag tctcaaaatc aaagacttat actcttcaaa
    33961 aatctcttca aaccgcgtca acgtcacctt ggattatata tgtgactgac ttcgtcagtt
    34021 ctatctacaa cctcaaagca gtactttgag caacctgcga ctagttttct agtttgctct
    34081 ttgattttca ttgagtatta aacaaaaagt gaacaaatct gaattctaat gtacagaaga
    34141 ctaggcttgt tcactttttt atagtcgcta taagatgacc ttatctatag ctttttatat
    34201 ataattatat attcagacat actattatca attttgtcgc agggaggaat ctgttaacgc
    34261 acccattcac cattatcatt gactctatag ccatctatac ttgtattgac cgctaactca
    34321 cccgatgtat ttacataata ccatttacca ccaacttgga accattgatt gactttcata
    34381 gaaccgttgc tgttgaggta gtaccatgaa ccattaactt gtacccaacc tgttgccatg
    34441 gaaccatcag tattataaaa ataccacata ccattttctt gtttccagcc tgttgttgga
    34501 gcaactgctt tagctggttc tactgctaca tctgttcctt ggttagatgt aacagataca
    34561 ggatacgaag gaatagatga ttgctcagga acaacaactt tttcaggttc tctcgtccct
    34621 ctccttatac gtctttttac catctcttta gtaatttgac gagaagtagt ttcttcaatt
    34681 gttccatcac gttcatctac agtatagatt gtagtaagag taatttacca atttctccta
    34741 cttcttctac ttcttgactt ttatcaagag ttgggccatc gagatattct gtttcgattg
    34801 aaatttcttg gacaagaact tggggcttgg ttcctttttt aacaactctt gtttgagagt
    34861 cttctttttg acttaaagta ctctcagtta cttgtccact ctttccatct acatcataag
    34921 ttatcgttgt aactattttc ccattctttc ctagagtaat ctcttgctcc tgtcctgcag
    34981 aaaggtcatt gtctgcttca tatttagtag caaatggaac aaaaacttct tcaaccttgc
    35041 ttttagctgg aactttgata actgtatccg tggcttcttt tctatcaaca gtaacctgtt
    35101 cggtaacatg accagtctct ggattaacat cgtaggtcct tgtcgtagtt acatagccat
    35161 cctctccatc aattgtaaca ggattttcac tacggtcttt tgtttcatct ttttcataac
    35221 gaattcgcgt acttgaaatt ttcttggtta ctaccttagg tttagtcgct acttttacaa
    35281 taatatcccc attgtcagcg tcatcatact ctattccctc ttctttatct ctagtatcat
    35341 ctctgacata ttgaatccca tcagcagcat gaacaaaact tgtattcaga ttcctcctaa
    35401 aaataaagtt agcccgatta ccgcagaacc aaaaatcttt ccgagtttac gtattgcata
    35461 gcgcttatta gtattagatt ttgccattac atcctacttc tagtatagca tcttttctat
    35521 caaacgttaa acaatatact ttatatataa aatagactta gaatgatata ttgattattg
    35581 aactaacact ttaactatat cgtaatcaat ctcatatata aaggattgca gacatcttat
    35641 ctaaatacat gctaatatat ttagatacaa acattccaac ttgataattt tcactcatc
//
LOCUS       DAVLAQ010000017        35105 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000017 DAVLAQ010000000
VERSION     DAVLAQ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35105
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.017"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(113..550)
                     /locus_tag="VXB71_000836"
     CDS             complement(113..550)
                     /locus_tag="VXB71_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0450978.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(635..3268)
                     /gene="polA"
                     /locus_tag="VXB71_000837"
     CDS             complement(635..3268)
                     /gene="polA"
                     /locus_tag="VXB71_000837"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0450979.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3524..3874
                     /locus_tag="VXB71_000838"
     CDS             3524..3874
                     /locus_tag="VXB71_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0450980.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4089..4205
                     /locus_tag="VXB71_000839"
                     /pseudo
     CDS             4089..4205
                     /locus_tag="VXB71_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            4198..4431
                     /locus_tag="VXB71_000840"
     CDS             4198..4431
                     /locus_tag="VXB71_000840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450981.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            4558..5864
                     /locus_tag="VXB71_000841"
                     /pseudo
     CDS             4558..5864
                     /locus_tag="VXB71_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5963..7585)
                     /gene="groL"
                     /locus_tag="VXB71_000842"
     CDS             complement(5963..7585)
                     /gene="groL"
                     /locus_tag="VXB71_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0450982.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(7601..7885)
                     /gene="groES"
                     /locus_tag="VXB71_000843"
     CDS             complement(7601..7885)
                     /gene="groES"
                     /locus_tag="VXB71_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0450983.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(8041..8436)
                     /locus_tag="VXB71_000844"
     CDS             complement(8041..8436)
                     /locus_tag="VXB71_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0450984.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(8514..9275)
                     /locus_tag="VXB71_000845"
     CDS             complement(8514..9275)
                     /locus_tag="VXB71_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0450985.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(9317..9943)
                     /locus_tag="VXB71_000846"
     CDS             complement(9317..9943)
                     /locus_tag="VXB71_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0450986.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(9959..10276)
                     /locus_tag="VXB71_000847"
     CDS             complement(9959..10276)
                     /locus_tag="VXB71_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0450987.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(10273..10572)
                     /locus_tag="VXB71_000848"
     CDS             complement(10273..10572)
                     /locus_tag="VXB71_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0450988.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(10857..11048)
                     /locus_tag="VXB71_000849"
     CDS             complement(10857..11048)
                     /locus_tag="VXB71_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0450989.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(11209..11883)
                     /locus_tag="VXB71_000850"
     CDS             complement(11209..11883)
                     /locus_tag="VXB71_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450990.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(11889..12335)
                     /locus_tag="VXB71_000851"
     CDS             complement(11889..12335)
                     /locus_tag="VXB71_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0450991.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPCYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(12449..12952)
                     /locus_tag="VXB71_000852"
     CDS             complement(12449..12952)
                     /locus_tag="VXB71_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0450992.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(12949..13311)
                     /locus_tag="VXB71_000853"
     CDS             complement(12949..13311)
                     /locus_tag="VXB71_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV0450993.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(13377..15236)
                     /locus_tag="VXB71_000854"
                     /pseudo
     CDS             complement(13377..15236)
                     /locus_tag="VXB71_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(15275..15724)
                     /locus_tag="VXB71_000855"
                     /pseudo
     CDS             complement(15275..15724)
                     /locus_tag="VXB71_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(15848..16564)
                     /locus_tag="VXB71_000856"
     CDS             complement(15848..16564)
                     /locus_tag="VXB71_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0450994.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(17445..18860)
                     /gene="ply"
                     /locus_tag="VXB71_000857"
     CDS             complement(17445..18860)
                     /gene="ply"
                     /locus_tag="VXB71_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0450995.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(18871..19203)
                     /locus_tag="VXB71_000858"
     CDS             complement(18871..19203)
                     /locus_tag="VXB71_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450996.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTGIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(19274..19882)
                     /locus_tag="VXB71_000859"
     CDS             complement(19274..19882)
                     /locus_tag="VXB71_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450997.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(19895..20353)
                     /locus_tag="VXB71_000860"
     CDS             complement(19895..20353)
                     /locus_tag="VXB71_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0450998.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            20478..20877
                     /locus_tag="VXB71_000861"
                     /pseudo
     CDS             20478..20877
                     /locus_tag="VXB71_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21642..21902)
                     /locus_tag="VXB71_000862"
     CDS             complement(21642..21902)
                     /locus_tag="VXB71_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0450999.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(21961..22512)
                     /locus_tag="VXB71_000863"
     CDS             complement(21961..22512)
                     /locus_tag="VXB71_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451000.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(22502..23497)
                     /locus_tag="VXB71_000864"
     CDS             complement(22502..23497)
                     /locus_tag="VXB71_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451001.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(23905..24330)
                     /locus_tag="VXB71_000865"
     CDS             complement(23905..24330)
                     /locus_tag="VXB71_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451002.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(24474..24842)
                     /locus_tag="VXB71_000866"
     CDS             complement(24474..24842)
                     /locus_tag="VXB71_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451003.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKK"
     gene            complement(24864..25070)
                     /locus_tag="VXB71_000867"
     CDS             complement(24864..25070)
                     /locus_tag="VXB71_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451004.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(25057..25218)
                     /locus_tag="VXB71_000868"
     CDS             complement(25057..25218)
                     /locus_tag="VXB71_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451005.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(25577..26533)
                     /gene="lytA"
                     /locus_tag="VXB71_000869"
     CDS             complement(25577..26533)
                     /gene="lytA"
                     /locus_tag="VXB71_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0451006.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(26909..28279)
                     /locus_tag="VXB71_000870"
     CDS             complement(26909..28279)
                     /locus_tag="VXB71_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0451007.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(28586..29752)
                     /gene="recA"
                     /locus_tag="VXB71_000871"
     CDS             complement(28586..29752)
                     /gene="recA"
                     /locus_tag="VXB71_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0451008.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(29807..31063)
                     /locus_tag="VXB71_000872"
     CDS             complement(29807..31063)
                     /locus_tag="VXB71_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0451009.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(31148..32164)
                     /locus_tag="VXB71_000873"
     CDS             complement(31148..32164)
                     /locus_tag="VXB71_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0451010.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(32172..32690)
                     /locus_tag="VXB71_000874"
     CDS             complement(32172..32690)
                     /locus_tag="VXB71_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451011.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGELFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(32680..33123)
                     /gene="tsaE"
                     /locus_tag="VXB71_000875"
     CDS             complement(32680..33123)
                     /gene="tsaE"
                     /locus_tag="VXB71_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0451012.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(33209..33829)
                     /locus_tag="VXB71_000876"
     CDS             complement(33209..33829)
                     /locus_tag="VXB71_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451013.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTVFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(34212..35075)
                     /locus_tag="VXB71_000877"
     CDS             complement(34212..35075)
                     /locus_tag="VXB71_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451014.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT        10582 a         7891 c         6046 g        10586 t
ORIGIN      
        1 caacctcaaa acggtgtttt gagcagcccg cggctagttt cctagtttgc tagtgtgctc
       61 tttgattttc attgagtata acacaaaagg tagcccatca gctacctttt tcttatgctt
      121 cctcaatcaa gcgagtatgt tctctcttga tacagcgatt catcacgata tcatcacatc
      181 caccatcacg caaaatctct ttcgcttcta aactttcaag tcctagctgt gcccaaaaaa
      241 tcttggcatc agctttgaga aaatcacgcg ccacatcggg cagaaattca ctgcgacgat
      301 aaacattgac aatatctaca ggaaaaggaa tttcagcgag gctagcataa gccttttcac
      361 ccaagatttc gccacctgcc gccttgggat tgactgggat gattttatag ccccgagcct
      421 gcatttcctt tgttactcga ttgctggttg tttcttcacg gtcagacaaa cccaccacag
      481 caagggtttt actcgttgcg agatactgac gaatcacgcc atcacttgga ttgataaatt
      541 cttgactcat agaaatcctc ctttttcatc agtatagcac attttgaaaa ggtttgcaga
      601 attatactac aaaaaaggag gactagcccc ctttttattt agcctcgtac caggttgccc
      661 cttcattctc atctgcgata agaggaacac tgagttgaat ggcttcttcc atggtttgtt
      721 tcaccaattt tttcatctct accaattcag atttaggcac ttcaaggacg atttcatcgt
      781 gcacttgtaa cagcatctta gtctgataac cacctgcaac caaggcttta tccagctgaa
      841 tcatggcaat cttgagaata tctgctgccg aaccctggat aggtgagttg atagcagttc
      901 gctccgcaaa accacgaata ttgaagttgc gcgaattgat atctggcaac tcacggcgac
      961 gcttaaagag ggtctctaca tagcccttat cacgcgcctc ccgcaccact tcatccatgt
     1021 agtttttaat atctggaaaa cgttcaaagt aggtatcaat gtaggctttg gcttccttac
     1081 gactaattcc caaattatta gacaagccaa agtctgaaat cccataaacc actccaaagt
     1141 taactgcctt ggcattgcga cggtcatttg cagtcacatt atcaggacgc tcaatgccaa
     1201 agacccgcat ggctgtcgaa gtatggatat ctgccccctc ttggaaggcc ttaatcaagt
     1261 gctcatcctt agaaatatgc gccaaaacgc gcaattcaat ctgtgaatag tcagagctga
     1321 gtagcacact atcctcccac tctggcacaa aagccttccg aatcaagcgc ccttgttcca
     1381 atcgggcagg aatattttgc aagtttggat ccacactaga caaacgcccg gtctgggtca
     1441 aatcctgcat atagcgagta tgaatctttc catcagccaa aatccagtcc tgcaagccaa
     1501 ttacataagt agattgaatc ttagcaattt gacggtaatc caggattttc ttaacaatcg
     1561 gagcaatagg agcgagacgc tccaacacat ccactgctgt cgaataacct gtcttggttt
     1621 tcttagtgta ttctagagga agtcccaatt tctcaaagag aagcacgccc aactgcttag
     1681 gcgagttgac attaaactcc tcaccagcca gctcgtaaat ctcttgagtc agtttttcaa
     1741 tgacaagctc attttcagcc tgcatctcaa gcaaggtctc tttcttgacc acaatcccag
     1801 caatttccat cttggcaaga acaaaagcca gaggttgctc catatcataa agaagctcta
     1861 attgcccatt ttcgctgagt ttttcaagta aaataggctc tgtttctacc aaaacagcaa
     1921 gtttacaagc taagtgttcc aagaatttct cacgttcagg aatggccttt ttaacaccct
     1981 taccgtagaa agtttcatca tcaaccaagt aagtctgacc ataaagacta gcgatggtcg
     2041 caatttcatt gtcctccaca gtcgaaagga ggtatttagc caaacggatg tcaaaagcag
     2101 gcgcctgcaa atccacacca aaacgttgca aaagaacttt aaccttctta aagtcataaa
     2161 ctctcagaga tgttttttct aagaaatcct tgaaaatcgg gtcttgcaac agctcaagct
     2221 tgtctgtggc atagagctta tcctcacaag accaggcaaa tccaaccaaa ttatccgtat
     2281 ggtaattctc accaaaaagc tcaaagtgga agatagactc ttcactcagc atatcttgac
     2341 tgatttggtc aacaatagta aaatccaaac ccttagccac atcagctgac gacacattta
     2401 aagcctgctt gagctgtttg aatcccatct catcgtaaaa tttcccaaga ttttcaacat
     2461 ctggaccact atagaccaag tcctctaaac caatcgcaat cggtgccttg gtatcaatgg
     2521 tcgctagtgt tttagacaaa aaggcctgtt ccttgtcatt gatgagattt tccttcatct
     2581 tagaagtctt cattccatca atattttcat aaatcccctc aagcgaacca tactccagca
     2641 agagcttaat acccgtcttt tcaccgactt tggtcacccc agggatatta tccgacttat
     2701 cacccatgag cgccttgaga tcgataaact gagctggtgt gaggcccatt tcttccatga
     2761 ggtaatctgg cgtaaaggcc tcaaactcag ccacaccttt cttggaaatt tcaaccaccg
     2821 tatgctcatc cgtcagctga atcaaatcct tgtccccact gacaatggta atatcaaaac
     2881 catcctgctc tgctagctta tccagcgtcc caatgatgtc atccgcctca tactgagcca
     2941 gctcatagtg acgaatcccc atatgatcca gcaactcacg aatgaaagga aattgctcac
     3001 gaaactcatc aggagtcttg gcccgaccac ccttatagtc cgcatacatc tctgtccgga
     3061 aggtcgtctt tcccgcatca aaagccacca aaatatgact cggctcaacc cgctccaaca
     3121 aatgactcaa catcaactga aaaccataaa tcgcattggt atgcaaacca gccgcattct
     3181 taaaacggtc caactgctga tacagcgcaa aaaacgcccg aaaagctaca gaagacccat
     3241 caatcaataa taattttttc ttatccatac acccattata aaggaaagaa tcaaaaaata
     3301 ccattgggaa gagctagagc aagtattttt caaacttttt ccgaataaat agatagagcc
     3361 agagaattta gtaaacctag atttaaaaat gtgctataat ataatatatt gaatctataa
     3421 tagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct gatagagtta
     3481 ttcacatctt atttcaactc actatagaag gaggaatagg aggattctca gacatccggg
     3541 catcagccca actaatgatt tgattgctaa gaaaatattc agcaatccag aaatcacttg
     3601 tcaatttatt cgcgatatgc tggacttgcc agcaaaaaat gtgaccattt tggagggaag
     3661 cgatattcac gtattactct ccatgcctta ctcggtgcag gatttttata ccagtataga
     3721 cgtcttggcg gagttggata acggtactca agtaattatt gagattcaag tccatcatca
     3781 gaattttttc atcaatcact tgtggactta cctgtgcagt caggttaatc aaaatcttga
     3841 aaaaattcgt cagcgagaag gtgatactca ctagagctac aaacacatcg ctcctgttta
     3901 cgccattgct atcgtggata gtaattattt ctcagatgac ctggcttttc atagctttag
     3961 tatgcgcgaa gacacaacag gtgaggtatt ggcgattacc aacaatggac aggaaaacca
     4021 tctggttaag atggcattct tggaattaaa aaatacagag aaaccagcaa agacaaggtt
     4081 cgcaagccat ggttggagtt tttcggcaac aagcccttta cccagcaacc gcaacgagcc
     4141 attagccaag caaatcaact gctggactac aagagctggt ccgaggagga caggaaaatg
     4201 tttagtcaac tacatatgcg agaagaacaa gtcttgttag cacaggacta tgccttggaa
     4261 actgctaggg ctgaaggcct tgaacaagga ctagagcgtg ggaaagttga aggaagggca
     4321 gaaaggaaac tttttgcctt cctagacata gtacgccaag gtcttctgac ttctgaggtt
     4381 gccagccagc aattaggtat gtcagtatct gaatttgagg cactgttgta aaatggctcc
     4441 ataatatcca tagtgggtaa atcccctatg gatattatgg agcctatttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattagaaa gaatcatatg
     4561 gaacaattac attttatcac aaaattacta gacattaaag accctaatgt ccagatttta
     4621 aacatcatca ataaggatac acacaaggaa atcatcgcca aactggacta cgacgcccca
     4681 tcttgccctg agtgcggaaa ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt
     4741 ccttatcttg aaacgactgg tatgcctact agaattctcc ttagaaagcg tcgattcaag
     4801 tgttatcact gttcaaaaat gatggtcgct gaaacttcta tcgtcaagaa gaatcaccaa
     4861 atccctcgta ttatcaacca aaaaattgcg caaaagttaa ttgaaaagat ttctatgacc
     4921 gatattgccc atcagctttc catctcaact tcaactgtta ttcgtaagct caatgatttt
     4981 cactttaaac atgatttttc ttgtcttcct gagattatgt cttgggatga gtatgctttt
     5041 acaaagggaa agatgagttt cattgcgcaa gattttgata atcttaatat tatcactgtt
     5101 cttgaaggca gaacacaagc tgtcatccga aatcactttc ttcgctacga tagagccgtc
     5161 cgatgtcgcg tcaaaatcat tactatggat atgtttagcc cttactatga cttggctaaa
     5221 cagcttcgct ttcaaatttc taggctcagg ctgaaacagt ctcccagact gtttcactcc
     5281 cgaatgctaa aatcgttctt gatcgctttc acattgtaca acatcttagc cgtgctatga
     5341 gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa atcccatgaa tacaaggcta
     5401 tcaagcgcta ctggaaactc attcaacagg atagccgtaa actgagtgat aagcgatttt
     5461 atcgtcctac ttttcgtatg cacttaacca ataaagagat tttaaacaag cttttgagct
     5521 attcggaaga cttgaaacac cactatcagc tctatcagct cttgcttttt cacttccaga
     5581 acaaggaacc agagaaattt ttcggactta ttgaggacaa tcttaagcag gttcatcctc
     5641 tttttcagac tgtctttaaa accttcctca aagataaaga aaagattgtc aacgcccttc
     5701 aactacacta ttctaatgcc aaactggaag cgaccaataa tctcatcaaa cttatcaagc
     5761 gcaatgcctt tggttttcgg aactttgaaa acttcaaaaa acggattttt atcgccctga
     5821 atatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagctgact tcaacccact
     5881 acagttgaca aagagcctat aaaaagaagg gttagtcatt ccctcctttt gtgtttttta
     5941 taagttgttt tctatagaaa gcttacatca tcccgcccat catacttgga tccattgctg
     6001 gagctggggc tactggttct ggtttattgg ctacgactgc ttctgttgtc aaaatcaagc
     6061 tggctacaga tgctgcattt tgtagggctg aacgactcac tttaactgga tcaatgatac
     6121 cttgatcaat catgttaacc cactcgccag ttgctgcgtt aaatcctata ccaagctcag
     6181 catttttcaa acgatcgata acgatagatc cttcaaatcc tgcattgtga gcaatttgac
     6241 gaacgggttc ttccaaagca cggagaacaa tattacgtcc tgttgcttca tctcctgtca
     6301 attccaaggt agcaacagct ggaatcacat tggcaagagc tgttccaccg cctgcaacaa
     6361 taccttcttc aacagctgca cgagtagcgt tgagggcatc ttcaatgcgg agtttcattt
     6421 ctttcaactc agtttcagtt gcggctccga ccttaataac cgctacacca cctgacaatt
     6481 tggccaagcg ttcttgcaat ttttcacggt caaattcaga agttgtagtt tcgatttgag
     6541 acttgataac cgcaacacgg tgagaaatcg cttcaggatt tcctgcacct tctacaataa
     6601 ccgtgctatc tttgtccacg gtcactctcg ctgcttgacc aagagcttca attgtcgcat
     6661 ctttcaactc aagaccaagg tcttctgtga taactgttcc gcctgttaag atggcgatat
     6721 cttcaagcat ggctttgcga cggtcaccaa aaccaggtgc cttgactgct actacgttga
     6781 aggttccacg aatcttgttc aaaacaagag ttggaagagc ctcgccatcc acatcatccg
     6841 caataatcaa gagtggacga ttgctttgga gaatgctttc caaaagtggc aagatctctt
     6901 ggatattgga aattttcttg tctgtaatca aaatgtacgg attttcaagg tcagccacca
     6961 ttttttcgct atctgtcacc atgtactgtg aaaggtaacc acggtcaaac tgcattcctt
     7021 ctacgacttc aagctctgtt tccataccac gtgactcttc gatggtgatg acaccgtctt
     7081 tgccaacttt ttccattgct tcagagatgt actcaccaac tttttcagaa cgagaagata
     7141 cggctgcaac ttgagcgata gcttctttat tggcaacagg gatggcgttg tttttcaaag
     7201 cttcaactgc tgcggcaact gctgtttcaa tcccacgacg aataccgatt ggatttgcac
     7261 ctgctgtgac gtttttgatt ccttcacgga cgatagcttg ggtcaagact gttgcagtcg
     7321 tagtcccgtc acctgcgata tcattggttt tagaagctac ttctgatacc aatttggcac
     7381 ccatattttc aaaatggtct tctaattcaa tttctttggc aatagtcaca ccgtcattgg
     7441 taatcaatgg tgagccaaat gatttttcaa gaacgacatt gcgacctttt ggtcccaagg
     7501 ttactttaac agtatctgca aggatatcga caccacggac catagctgaa cgggcatctg
     7561 atgaaaattt aatttctttt gacatactta ctttctcctt ctattcttca atgattgcca
     7621 agatgttagc ttcgcctacg atgatatact tttcatcgcc atctttgaca tcaagacctg
     7681 cgtgggcttc aactaagaca cggtctccag ttttaacact tggagcaacc aagtcaccgt
     7741 tcaaggtacg aacaccttgt ccagtagcca caacttgggc tgttttggtt ttttcttggg
     7801 ctgaacctgc gagaacaaag cctccaacag tttgttcttt ttcttctact tttaagacca
     7861 aacggtcccc taatggtttc aacatctgat ttcctccata atgagataga tattattagc
     7921 actctttata cctgagtgct aattcatagt tctattgtat cacttagtca gaaataatca
     7981 agaaaaaagt ctgactttct caagataaaa agcctgagac caactcagac tttttaattc
     8041 ttaaaatggc aattcttcct cttccaagac caaatctgcc aaatcttggc ctgcattatt
     8101 ttcacgcata gcacgttggg cacgactttc caagagttgg aatcctgtca caaggacttc
     8161 ggttacataa ttcatctgac catttttctc aaagcgacgg gtacgcaatt ctccatcaac
     8221 ggaaatgaga ctacctttgg ttgcgtagct tgccaaagtt tctgctagtc tgccccatag
     8281 gaccatattg acaaaatcaa cttcacgttc accgttttgg tctttgtaac gacggttgac
     8341 agcgatagtt gctcgcgcta ctgacttgtc attgttggtt ttgtgcaatt ctggtgtaga
     8401 cgttaaacgt ccaatcaaga taactttatt atacatattt tcttcctcct acttatctat
     8461 tcgtaggaaa tcaaaaaaag ttacagaaat ttgtaacttt tcgagaaaat tttttatttt
     8521 ttatgaacca tgaaacctgt cgcctgttga ttggccataa tggtcatatc tgtaatctga
     8581 acacgacgag gttgactagt cacatagact actgtatctg caatatcctg agcttgcaaa
     8641 gcttctattc cttggtaaac ggacgcagct cgttctttat caccatgaaa acgcactgta
     8701 gaaaaatctg tttcgacaat tccaggctga atggttgtca ccttgatatc cgttgcgatg
     8761 gtatcaattc gcagtccatc cgaaaaggtc ttaaccgcag ccttggtagc tgagtaaaca
     8821 gcggcaccag cataggcgta gattcctgcg gttgacccca tattgataat atgaccttga
     8881 ttgactttta tcattgctgg caagaaacag cgagtaaccg ccatcagacc tttaacattg
     8941 gtatccaaca tggtcaacat atccaactcc tcatagtctt gatagggagc caagtcaaga
     9001 gccagtccgg cgttgttgac caagatatca atcctcccta tcgtttctag aatatcagag
     9061 caaacagtct tcaccatgac catatccgtc acatctagtg gaaaagtcca gacggtttga
     9121 tttggaaagc ttactgcaaa ctccgacttg aggatttcta atctgtctat ccgtcgtcct
     9181 gttagaacga catcctcacc ctgctccaga taagcacgcg caatcgcttc accgattcct
     9241 gaggttgctc ccgtaatcac aacatttttt gccatcttat ttccttctag ctggtctatc
     9301 agatattaac aacttcttag gcagtccagt gtttagctga gtcaaatggt gttccgacaa
     9361 cttggtcttc tgataattca agcaccccac gtttttgtgg agcatttggc agatgcaatt
     9421 cacgaggact gcacatcata ccaaaactct tttcaccacg aagttcacct gggaaaatga
     9481 gattcccttt tggcatcata gctccaggaa gcgcgacaat ggttttcaac cccacacgcg
     9541 cattgggagc tcctgcaacg atttgtacag tcttatcact tgcgactgca acttggcaga
     9601 tgttgaggtg gtcactatct ggatgggcta ccatctcaac aatttcaccg acaacaaact
     9661 taggttcctt atcattaaca atttcttctg taaaaccttc cgcctgcaac tcttggttca
     9721 aacgagcgac ttgctcatct gtcaaaaaga cttgaccgcg ctctgcagtt tcaaataaac
     9781 ttgaaacttc gaaaatattc caagccactg tttccccatt ttctttgagg aaaacacggg
     9841 ctaccttgcc tttgcgttcc acattcagtt tggcatctcc gctatttttc acgatgacca
     9901 taaggacatc accgacatgt tctttgttat acgtaaaaat cattgtttcc tttttctcct
     9961 atttcaatcc tgctaaaaaa tcgttaattt gctccttact tttacggtcg cgattgacaa
    10021 aacgaccgat ttccttgtcc ttttctagaa caacaaggct aggaattccg taaacatccc
    10081 agagtttggc caaatccata tactgatctc ggtccattcg aataaaggtg aactctggat
    10141 tggtctcttc aatctctggt aaggcaggat aaatataacg acaatcgcca caccagtctg
    10201 ccacaaaaag gaagaccttc ttgcccgctt tttccactaa agatgctaat tcttctaaac
    10261 ttgctggctg tatcataaga cttcctcctc atagactagg tcttcatttt catagacaaa
    10321 ggtataatga cggccatcct caaaaatgac gccaccaacc aagctctcca gactgctttc
    10381 gtaaacttga acataaaggg tcgcaatttc ccccatgtcg gaaaaatggt ctcgcacaat
    10441 ctctgtcaac tcttcctgag tcttcatgag cttacggtca tctgcaactt ttttcgtagc
    10501 aagggcaagg cttccgatac ctagcagagc caagcctgcc atccacattt ttttagcttt
    10561 cataccattc attttaacac aaaaaaggct tcaggacaaa tgaggaagca gcagaaaagc
    10621 aagtaaaaag cctcttcctt taaggaaaag gacttcttat actaagagca aactagaaag
    10681 ctagccgcag gctgctcaaa acacggtttt gaggttgtag ataaggcgac gttgacgtgg
    10741 tttgaagaga ttttcaaaga gtattattct tattgccagg cacctaagtt gccaacgtag
    10801 taaccatcag gtgtgtaggt attgcgaagc atcttacctg atgaagccag ataatactac
    10861 ttgccattgt ctttgaccca atcattcgca atcatggaac cagaagaact tacataatac
    10921 cattctccct tgtcataaac ccaagtactg actttcatgg ttcctgagca attaaaggca
    10981 aaaaaactgt ccaatatcat tcgtttttta aaagcattcg acactacatc atctacgctg
    11041 tagtacatag atacatcaaa cgtaaaagcc aaaatatcga aaaatataca acttttaaag
    11101 gcagcatttc attttttaaa gtctaacaac catagaactg aaatcagagc aaggcatcaa
    11161 tttcctactc tatagtacgc ctattttgat ggttgaagtg aagatttttt atttaacgta
    11221 gacaatttcc aacttcccaa aagccacatc tccacggata atcaaggttt tgctggttgg
    11281 ggctacagga gcgtcagcct tagctgcacc aaaggaggtt tctactttca aatctacacg
    11341 ccagtgttgt ggaacataga cggttgcatt tccgaaggct acttcaatat ttaaagttgc
    11401 aaaatcacct agcatctctg cattatcata gtagatttta gcatccccaa aagcgacttc
    11461 cacttggtca tctacgagat cttgatcttg cttatagaag gtcccgctac caaaagcgac
    11521 ttccttatcc gtgacgactg tttttttccc attgtaccac catttttttt cattccagaa
    11581 cttacttgaa tgcgtcagat aaccaacacc aagtaccacc aagatgctag cccaaataag
    11641 agaatgattg gtaactggta acaagtcata agcgtaattt gcaatgatga gcgccagtaa
    11701 acctgtaaaa actgccgaag tgagatgacg tctaaggatg gactcaatgg acttataagc
    11761 aaaaaaaaca atacctagta aaggccatat tttaccatcc aaagaaggaa ttccaaaatt
    11821 cccttgcagc aagatccaag ctgctaaaac caataaaaca ataccaaatg ctttcttttt
    11881 catgtttttt acctcatgtt tcttagattt tcttttagga gggattggta atgccgtgag
    11941 acatgaacct ccttgtgcgt ctgataaaag gaaatggtgc ccgttcctga aaaggacttg
    12001 tccactgagt aaatctgacg gatgtttgcg atcgttgact tggaaactcg attaaaatag
    12061 caaggcaaga tagactccaa ctcatagagc ttgaggcgaa cctcataagc ttccttctgg
    12121 ttatgagcgt agatcttgct cccttctgtt tcaaagaaga gaatttctga caggtctaga
    12181 taatattcac ctgtcccctt gtaaaaagtc aacctcggag cctttgactc ttgcaagagc
    12241 cgttgcaagt ctgcaatttc atctgtcaaa gtgggggtct tgatgacaat ttcagtctcc
    12301 tctaaattgc cgtcaatctc aattcgtaac ttcatcacat ctcctttctg actctactat
    12361 atcaaagcta agttaggaat acaagggcaa aaaagcaagt ggtcaatttg aagcagtaag
    12421 tggttgtagg actagcttaa cttacatgtc agaataggaa gaaaaggaat ccccacacca
    12481 aaccacaagc atagccaacc aagacatcct tgggataatg aacaccccct aaaaccctca
    12541 ccaaccccag caaagctgaa aagatcaagc atactaagcc aataggtaga ctagcatgca
    12601 gacaggccat ggagatgata gttgccgaaa agacatggcg actgggcatc gaccgtcccg
    12661 aactatcctt atcaagaagg ggacagatat cccaagtttc ataaggtctc gggtgattga
    12721 ttttcttacg aaacagggac aaggtcacaa aacctgatgc aggaataagc acataaaccc
    12781 caacttgctg accaagtcct agttgcaggt aagtggtgac tagcaagatc agatagacca
    12841 ggggcatggc gactgtcatc aaacgattga aactgcgtaa taggaataaa agaattggac
    12901 gactagttag tctggagctg atatttcgat accattcttg ataatttttc atttatgctt
    12961 ctcatacttt tctagaactt gttgagatgt tttccccttg gcaagccaat ccactagctt
    13021 gtccaagcga cgtatttcct gcatcagagg atcatcaatt tcctcaatac ggacaccgca
    13081 aatcttccct gtaattgcaa ttcgttcagg gacataatat ggtgcttgtc taaaaaaatc
    13141 tccgtaagta acatccctat ccagacaagc aagaacatca ctcacttcat accctgtcaa
    13201 ccaactggtc acttggtgaa ctgactctgc ctttccaccc tttcgctcaa cttttgcaat
    13261 caaggctaag tagacagcag caaatttcat attgtataat ttctgactca tacttctctc
    13321 tttctatgtg tactagtata aataagaaaa agaaggccgt caagccttct tttgatttat
    13381 tcttctgctt catcttctgt aaattgacta ttgtacaagt cagcgtagaa gccaccttgc
    13441 gccatcagtt cctcatagtt gccttgctcg atgatatttc catctttcat gaccaagatc
    13501 aagtctgcat ttcggatggt tgacaagcgg tgggcaatga caaaggatgt gcgtcattcc
    13561 atcaaacggt ccatggcttt ttggatcaat tcctctgtcc gtgtgtcaac agaagaagtc
    13621 gcctcatcca aaatcaaaag cggtgcatcc ttaagaaggg cacgagcaat agtcaatagt
    13681 tgtttttgtc ctacagacaa ggtcacggtg tcatccaaga tggtatcata gccatctggc
    13741 aaggtcataa taaagtggtg aattcccaca gccttactag cttccatcat tcgttcatca
    13801 ctaatcccta tttgattata gatgagattg tctcgaatag ttccttcaaa gagccaggta
    13861 tcctgcaaga ccattgaaaa ggcatcatgc acttctgaac gcgtcatagc cttggtatcc
    13921 acaccatcaa tgtgaatact tcccttatca atctcataga atttcatcaa aagattgaca
    13981 atggttgtct taccagtccc agtcggccca acaatggcaa ccttttgacc agcatgagct
    14041 gtcgcagaga agtcatagtc ttgaacattg acaccgtcca ccagaatttc tcctgctgac
    14101 acgtcgtaga aacgtggaat cagattgacc agagttgatt taccagaacc tgttgaccca
    14161 ataaaggcca ctgtttgacc agtttctgct ttaaagctaa catgttcaat aactgcctcc
    14221 gaatttgccg catagcggaa ggtcacatcc ttaaactcga cctgaccttt gaagttttca
    14281 tcagtcagct gcacttgaac agggttttgg atagaagaat gcaaatctaa aacttgatta
    14341 atccgcttag cagagaccat agttcgggga agaacgatga agagtgctcc catgagaagg
    14401 aagcccatga caacctacat ggcataagac atgaaaacaa tcatgtcact aaagagaggc
    14461 agacgcgcta tcgaagcagc gtcgttaatc acataggccc caatccagta aatcgctaca
    14521 ctcaaaccac ttgaaatccc catcatgata ggattcaaaa tagccataag acggttgaca
    14581 aacaaattca aacgggtcaa ttcatcattt actgctgcaa atttttcatt ttgataatcc
    14641 tctgcattgt aggcacgaac gacacgaata cctgttaaac tctcacgagt gatactgttc
    14701 agtttatctg tcaacccctg aatcaaggac tgttttggaa aggctagcgt catcaaaacg
    14761 gtcgtcatca ggacgttgac aatcactacc acaagtacgg cccagagtca gtattctgaa
    14821 tgacctaaaa tcttcccaat agcccagata gccataattg gaccacgcgt taccacttgc
    14881 aagcccatag taatcaacat ttgaacttga gtaatgtcat tggtagtacg cgtcaagagg
    14941 ctaggaattg aaaatttctt aatctctgtc tgcgagtaat ccaaaactcg gttaaaaata
    15001 tcacttctca gcctactagt ataagaagcc gccactcggg atgcaaaaaa tccaactgca
    15061 actacggaca agaaggcaag aaagagcatt cccatcatca tgcttgccgg ctgccacaac
    15121 tcatctaaat tagtttcttg actacctagc aaatccgtaa ttttcgagat ataggtcggc
    15181 acttccaact ctagatagac cgaaaagcaa gtaaagaaaa tggctagtaa aatcatcccc
    15241 cattcttttc tactaattct tttggttaat ttctttattc tctcctccta ttcccttgat
    15301 attttgcctg tagttgaccg agaactttct caaaaatcag taattcatct tcatcaatgt
    15361 cttccatcaa ctgcttgtct atgcgttcaa aaaaagcctt aacctgttgc atctgagaac
    15421 gtgctttgtc cgtcagacga acaaacttag cccgcttatc aacaggactc gcctccaatt
    15481 ccaccaaacc attttgcact atacgcttaa ccagattact agcaacagac ttggtaatat
    15541 tgagttcctg ctcgatatct ttaatcaaga ccaagtcttg gtttttctag cgattatcca
    15601 aaaaacgcac aacctgacct tgcggcccac ccataaattc aatgccgcaa cgtttggctt
    15661 ccttttgcac catcaggtga atttgatgac caaaacgctt aaagactaac atcggtttat
    15721 ccataatctc ccccttctaa ataaaaatag ttctctggag aataattaaa tttctatgag
    15781 aactattttc ttgattaaaa aaatcccaag tgattttctc acttaggatc atgttctata
    15841 ggttaaatta aaacccatct acgttcgtat aaatcttttg gacgtcttcg tcgtcttcaa
    15901 gaacgctgta aagtttttca aaggtttcaa ggtcttcgcc tgacaattcc acttctgact
    15961 gaggaatcat ttccaattca gtcacttgga attcttcaat accagactca cggagagcaa
    16021 cgatagcctt gtgaaggtca gttggcgctg tgtaaactgt gattgtacct tcttgtgctt
    16081 ctacgtcatc cacatccaca tccgcttcga gcaattgctc aaagactgcg tctgcatctt
    16141 cacctccaaa tacaataaca cctttgttgt caaagaggta agaaacagaa cctgaagcgc
    16201 ccatgtttcc gccgttttta ccaaaggctg cacggacatt ggctgctgta cggttgacgt
    16261 tagaagtcaa agtatccaca attagcatag agccatttgg cccaaaacct tcgtaacgtc
    16321 cttctgtaaa ggtttcgtct gtgtttcctt tggctttatc aatcgcttta tcgataatgt
    16381 gttttggcac ttgggcttgt ttagcacggt cgataacgaa tttcaaagct gagtttgatt
    16441 ctggatctgg atcacctttt ttagctgcta catagatttc tacaccaaat tttgcatata
    16501 ccttagagtt agctccatct ttagccgttt tcttggctac gatattggcc catttacgtc
    16561 ccattaggaa tctccttttt tcacatttta atctttatta ttataacaca agtttttttg
    16621 attttcacta gaggaaatgg attttattag caaatcaagc taggatagca ctttacctgc
    16681 taagatggtc ttacctttct atctttatca acagacactc atccacattc aaaaaacaaa
    16741 ctagaccatt atctgcaaat agaaagtttc agccaagttt gacaaagtca gctcaaatta
    16801 ctgtttgaag tttgtagata taagcgacaa aaacaatcat actgcacctt ttgttgacag
    16861 tctactccag acatatcata gttcaagtaa atactttgaa attcaacagt tcttataggc
    16921 gctattgtat tctaagaaat caatagaaga gtttctaagc aaacctctaa tactcaataa
    16981 aaatcaaaga gcaaaccaga aagctagccg caggttgctc aaaacactgt tttgaggttg
    17041 cggatggggc tgacatggtt tgaagagatt ttcgaagagt ataatttacg tgttcccaag
    17101 atggagaagt tagactagta cactggcact tctaaaccat tgctagcaat tgatttgttc
    17161 atatttaatt tcattttttc cataaatggg tattagatat aaacagcaaa atatttccga
    17221 tacgtgtcgt tcttgaattt ccaatcatct aaaacaagta aaggataatc aatcccctgt
    17281 atatcaagga attggctacc ctttttactt ttttacacat tctgtttgat agattcattt
    17341 taacatcacg agcatactcc aatggaaatc gctaggcaag agataaactt tcagatatcc
    17401 gcagagagat catcgcctct ttttgtcgca agcattctcc tctcctagtc attttctacc
    17461 ttatcttcta cctgaggata gagagttgtt ccccaaatag aaatcgtccg cttacgcact
    17521 agtggcaaat cggttttttc ataaaccgta cgccaccatt cccaggcaag cccggtacac
    17581 tctctaattt tgacagagag attacgaaca ttccctttta aaggaatact agtggtaaag
    17641 tgagccgtta aatcctgccc atttctgtcc caagccttag gagtcaagac ttccttacct
    17701 tgatgatcat aggataattc attccaagta atataatatt gggcaacata ggcaccacta
    17761 tgatccagca gtaaatctcc gtttctgtaa gctgtaacct tagtctcaac atagtctgta
    17821 ctattttgaa aggtcgcaac tacattgtca cgtaaaaaag aagttgtata ggaaatcggc
    17881 aagcctggat gatctgctgt aaagcgactg ccttcttgaa tcaagtcctc taccatatcc
    17941 accttgcctg ttacaactcg ggcacccgaa cttgggtcgc cccctaaaat aaccgccttc
    18001 acttctgtat tgtccaaaat ctgtttccac tctgtctgag gagctacctt gactcctttt
    18061 atcaaagctt caaaagcagc ctctacttca tcactcttac tcgtggtttc caacttgaga
    18121 tagacttggc gcccataagc aacactcgaa atatagacca aaggacgctc tgcagaaatt
    18181 cctctctgtt ttaaatcctc taccgttaca gtatcttgaa acacatctcc tggattttta
    18241 acagcatcta cgctgactgt ataataaatc tgcttaaaat taacaatctg aatctgcttt
    18301 tcgcccgaat ggacagagtt aaaatcaata tcaagagaat tccctgtctt ttcaaagtca
    18361 gaaccaaact tgaccttgag ttgttccatg ctgtgagccg tgattttttc atactgcatt
    18421 ctagctggga cattattgac ctgaccataa tcttgatgcc acttagccaa caaatcgttt
    18481 accgctccgc gaacacttga attgctgggg tcttccactt ggagaaagct atcgctactt
    18541 gccaaaccag gcaaatcaat actataagtc atcggagcac gatcgaccgc aagaagagtg
    18601 ggattattct ctaacaaggt ctcatccact acgagaagtg ctccaggata gaggcgactg
    18661 tcgttggtag ctgttacaga aatatcactt gtatttgtcg acaagctccg cttctttctt
    18721 tcgataacaa caaactcatc gggtagctga ttaccctctt tgatgaaacg attttcaata
    18781 ctttctccct gatgggtcaa gagtttcttt ttatcgtaat tcatagctag tataaagtca
    18841 tttactgctt tatttgccat cttctacctc ctaataagtt cctggattga gttgcataaa
    18901 ctcagacttg ttcagcgaaa tcagccgtgg ttggactaag taatccaaaa tttcctcgta
    18961 caattcttct gagacattgc gtcgccgtct ggctagataa gaagtcggaa tgcccgtatt
    19021 atccaacata aataccttat ctaagtcaat caaggttggt cttgtaaaag gattacgagc
    19081 tagatccggc tcttctatca taaagttctt gaccaaacgt ctggtcaaga gagctggttt
    19141 gaaggtctga tttttaacca actctttgtt tttagtcatg ctgttgtcaa tacagatata
    19201 catatgattc ttcacagcca aatcgctact aatagtcgga aaaggcaaat aaagagctac
    19261 aacatctcct ctcttaatca agcaagagca cccccttttc tcctaatgta acatagacag
    19321 gattgaccaa gtcttctgat tgactcagaa tttccaaagt ttgagtttgg cgcgctgtca
    19381 atttagtagc atcttgtctc ttcaatacaa aatgcttgtc gccaataacc ttgacaatat
    19441 aatccttctc caaagctgac tggtaaatcc acatcagatg ttgtctgtcc tgagaactca
    19501 agagagaagg attttcaagc ctcccgatag tctgataaaa atcaaaaaca ggagctaact
    19561 cctgccaatc tgattggcta gttgtcaagg ctagaaaaag ggctttgcga gctgatactt
    19621 cttggttagc cttgagagtt actttcccct ccaagttttt tagaaatcgg gaaactccag
    19681 aaagcaaatt tttctctaac tgcgagaaat aaaaaccttt cgttcccaga cataagtctt
    19741 tcatgtcgct ttctctagca aataagagct caaacatttg atagtaaaag aaaaatatct
    19801 ggcactgggt cgcgctcatc ttttccttat cggcttcttt ttttaaccag agcaagggcg
    19861 acaggtaact ggattgagac atttcctcta cctcctactc ttttttaact ggagcatctg
    19921 cactagctgc cacttctttt gactggatac tttcccactg gttaatctcc tctgagataa
    19981 gaccttcgca tgtcttgaca aatagggcaa aagccttggt ctttcctgca tatttctccg
    20041 tttggcattg atagaggaat ttttctttct ccaggagttg cgcagttttt tggtaagaaa
    20101 tccaattttc ctttgcatta tacaaattga taatcccctc acacagcaag ccgagactgg
    20161 ataaggcaac cgaaatcaaa cggtagcgat cacctggcat aggaatagca caaaagacag
    20221 ctatgaggaa acctgccacg atttctgtta tttttaatac cttatagcgc ctacgatgtt
    20281 gaacgctttt ctttaaaaaa tgagctatct gtacgtctaa tcgctctgtc aggtacattt
    20341 cttctggcgt catattcgta actcctttca tttactttga taaccatagt ataacatatt
    20401 tgaatatcaa agtatagtaa aaactggact ataacttatt agacttcctg cgaaacaaaa
    20461 tatggtatag tagttctatg aattatgaag caagtaaaca actaactgat gcacgattta
    20521 agcgtcttgt tagtgttcag cgtaccactt ttaaagagat gttagctgta ttaaaaacag
    20581 cttatcaaaa aagtcggaca agctggtaaa atcttggctg acagtggtta tcaagggctc
    20641 atgaagatat atcctcaagc acaaattcca cgtaaatcca gcaaactcaa gccgctaaca
    20701 gttgaagata aagcctgtaa ccatgcgcta tctaaggaga gaagcaaggt tgagaacatc
    20761 tttgtcaaag taaaaacgtt taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc
    20821 ttcggattac gaatgaattt gattgctggt attatcaatc ataaactagg attctagttt
    20881 tgcaggaagt ctattatata tatgcacaga catatgaaat ctttttgata cagccttctt
    20941 tttacataga gagacagcag ttatgatata tttatccatt cacaaaatct tctgtaccaa
    21001 tactacaata attggtacat tttgattaca caatcgtttc aaaaaatatg atggaagact
    21061 gagtatttta tagtaattcc cttcctatca actagatcaa ccagttgagt gttgaatgtt
    21121 gaaacaccct agcctcagca aaggactatg atcagcattt cctagccaat aggacgctcc
    21181 aaatcaccta ttctaagtcc atcactagct tggtcagtaa gatacagact gcaaggcaag
    21241 actgacgtgg ttgatgagat tttggaagag tattacaatc atagattcac cagtagactt
    21301 gaccgcagat ttaactatag tagattgaaa ctagaatagt acacttctgc ttctaaaaca
    21361 ttgttagaaa tcgatttgac tgtcctgatc aatttgtcct gttctcgttt cattttacta
    21421 tactaaaaaa ccacctgaaa caaatcaagt gactagagga taaaaacaaa gactgggcaa
    21481 aaagttttga aaagcaaaaa acgcataata tcaggtcttg aaaaaccttg ctactatacg
    21541 tttgattgtg ggaagattga cttcattttc tcctgaaatt gaagtttttt ctagtttcca
    21601 ggtatagacg aattcaatat agccatctcg ctacaattat tttaaccatc gaaaaaattt
    21661 ttcagaattt caaaaatttc attttgatcc aatgaaatgt cattattttg aagaatagtt
    21721 gacttcacag gctctaattc tatcacaaag cggtgcatgt ctgcttttac cgcactactt
    21781 gatgttatag ccgataactt ttcatctcct agcaaggaag ctgtcaaacg ggtaaggtca
    21841 ttcaaatgct ttttaatgga cttacttaaa ccttgagcac ctgtggcaga gcgctccctc
    21901 atatccagcc aagctttagc cttaaaaata attaatactc aatgaaaatc aaagagcaaa
    21961 ctaggaagct agttgcaggc tgctcaaaac actgttttga ggttgtagat ggaagctgac
    22021 gtggtttgaa gagattttcg aagagtatag accacaatta ctcaataccg aatacccctg
    22081 aatggtttct tttacatgca ccaatatatt ataataatct tcatccaata ataaggctga
    22141 taaactagca tcttggtcaa aatataaggg aatttctcga ccgtccttct ttaatggata
    22201 ttctggtaag atactaaata gttcaatcat agaaggaaac tcagaattag ttgttgtaaa
    22261 tcgaaaaagc tgcgctttct catctttctg acttccttga tactctccca attctaaaaa
    22321 atgattcaag gtagtataaa attccttatt ttttacttca tcaatgatga ccatatcata
    22381 atcttttgtt gtgcgacttt taaatccttg cgaatccaat acgatagagg tagcagttcc
    22441 cccaatcaga acataatagt tctgaaaatc cgcaaacatt tcttgaaaaa taactttcgt
    22501 attagctggc atcatcttct cccagatact gtaatatcat attttctagt gcttcactct
    22561 cttcctctat acgtgggtca tcatcatctt ttaaggtcaa ataaagagaa atcggatcta
    22621 caaattgttt atcatgatta tttttaaaat cattccaaaa ctcagataca aaaggacgat
    22681 atttccatat ctctagcatc tttcctttta aaatatgctg agaaagtggc aaggataact
    22741 gattgaattt tctctgccat atgacatagc tagtattttc atccgtttca gctaaaaaag
    22801 ttgaatgcga caaagcataa gcaccaccat atagaaggtt agaaacagat tttatctgct
    22861 ttatatcgcc atctggcaat aaaatccgtt ttttgatggg attaaataaa catgacacgg
    22921 attttaagaa taattctttc tttgacaccg tatatgtgta aagcttattt tgcttgttta
    22981 accaatataa agctttaaaa gtcctcaaac acctataaat tgttgagttt ggaagtccag
    23041 tgacttgtga aagcaaatca acatctacta ctttttgacc ttttgtcaat aaaaaggcaa
    23101 tccacgttaa ttgttcgcta ggtgttaatt ccttagggac ttcagtatca ttcgcattga
    23161 gtactagtcc caatggaggg aagaagaggt ttcccttaaa gtctacaaac ggaactctag
    23221 cttgaagtaa ttgctttttt tcactgtctg ataacttcga aaacaccaaa acaacatcca
    23281 tattggcttt ttcacccata gtgcgagcct gagtaacaaa tgaactcaaa ctcccccttc
    23341 tcttttcttt aatcaataaa aatgattcct tatgaaaagt catttgagta tactcaaacc
    23401 tttttacaaa actgattggt aaagtcaaag tcagttcctc aatactgaca tcaacataaa
    23461 aggattgaaa aattgacatt atctttttga cattcatgtt ttttccttat tctatcattt
    23521 ttattatatt ttatcattcg gtataataaa atataagttt tttgataaaa taaccaaaaa
    23581 ctactcccta tcccctctca cattacccta catatcgttt gacatgcgac tgatagttca
    23641 ggaaaacttc aaggagaact tttctctcat ccactatgca ggacttacta tttcacttct
    23701 actcctatag gctcaatttg acacttttct ttttcgaatt gctcatatgc ctcctgaata
    23761 gtgagttcga tttatccaaa tttatttttg tctattttga tgaatacttc cacgaagata
    23821 gtctgaaaat gaatttgcac caattttcct tctcttttta agcatattat tccagatatg
    23881 attgccctct tgttcagtaa taaattacgc tttaaacgct tcaatcagta tatctcctgt
    23941 tgtcatatgt tctaaagaaa attcttctac atatgattta acatctctta ggttattact
    24001 tcctaatatc ccattatgct ttttcgctaa ggaaatagaa gccgcttctc ccttaccaat
    24061 aatcttgtta ctatcatgat ttcttgttaa atctctatat aatgcgtatt cttcagttcc
    24121 aatgtctatg ctcacaatct cagctgaacc cttagctacc aactgatcta tcctagattt
    24181 taaatgggga attgtaggta tattgatttc atcatacacc tcttgtggaa taacaatttt
    24241 acccgaatag agcttttcta aaagatgttc agtaccaacc cataaaaata ctgaaataca
    24301 atctgcatca ataaatacac gactagtcaa acgacaactc ccccctcttc atctagccca
    24361 tatacaatat catatctgaa agcatctagt aacagttcct catacttccc ttgcgaaatt
    24421 ctgttatttt ctaaaagttg ttcagttgaa ttaacatatt atcctaatat catttacttt
    24481 ttactttctg acaaaggacg atataaactt gtatcatagc ctaatcttga agctgtctct
    24541 ataacactaa tatccatatt tttaatttct tctgcatcaa ggtatccatc attcctcaat
    24601 ctatataaca taactttatg actgatacca taaaactgac ccaattttat aatatcttct
    24661 acttcaagat gagttctatt ggcattttct ctaatttcct caaccatcct atacagtgaa
    24721 gatgggaaaa ttaaaaaata agaagcaaac tgatccgctt ttctttcagt ttcatctcct
    24781 tcaccaatca agataagact gactgaactc ttcttcacct catcataata aagatgatac
    24841 agttcatgtg ctaaagaaaa tctttacctt cctaatgaca tgtctgaatt gactgcaatg
    24901 agactgaact gagttccttt ataacagact ccgctaatat tctttccgag tccataaaat
    24961 accagcgtca aattttctat cttttgtacc aatttaaaaa tatctatcgg cgattcacca
    25021 tcagctccca acttttttct aagatttgaa gctttattac ttaaatccat tcgtgatatt
    25081 cctttcacct ttttccattt tggcaatcat gctttgattc aaagacaaat actcagcaat
    25141 cttatcttga gtaagatttg aagatattct aagttctttt attctttttc caacatcaca
    25201 tacatttatc acatacattt atcatattca tacacctctc ataaaaagaa tagcacactt
    25261 ttgtcataat tttttaaata aaaaaattat gacaaaacaa ggaagcaatt tattgatgct
    25321 gcttaaaaat ctaaaattga tgagttccta tcaaaaatcg tatcttcaac ctcaaaacag
    25381 tacttaaagc tatccgactc ggtttacatt gtcaaattta gattttattt gagcataact
    25441 ttctagtttg ctttctgatt tttgtttaat atagtagcaa acattgaagg aaatatctcc
    25501 acaaaaaaac gcatactatt aagctttttc aagacctaat aatatgcgct gttctgattt
    25561 gaaagacatt ccattattat tttactgtaa tcaagccatc tggctctact gtgaattctg
    25621 gcttgtctgc cagtgttccg tctggtttga ggtagtacca gcctgttccg tccgctgact
    25681 ggataaaggc atttgatacc atggcgcctt ctttagcgtc taagtagtac caagtgtcct
    25741 tgtacttgac ccagcctgtc ttcatggcac cttcttcgtt gaaatagtac cacttatcag
    25801 cgattttctt ccagcctgta gccatttcgc ctgagttgtc gaaccagtac cagttgccgt
    25861 ctgtgtgctt cctccagcgg tctgcaagca tatagcctga actgtcaaag tagtaccaag
    25921 tgccattgat tttctcaaac ttgtcttttg gataagagcc gtctgaatgt acgtaccagt
    25981 agccagtgtc attcttctgc cagcctgttt caatcgtcaa gccgttctca atatcatact
    26041 taaactgctc acggctaatg ccccattttg ccaagtaagg gtatggatcc acatggtctg
    26101 agtggttgtt tggttggtta ttcgtgcaat actcgtgcgt tttaattcca gctaaactcc
    26161 ctgtatcaag cgttttcggc aaacctgctt catctgctag attgcgtaag agttcgatat
    26221 aaaggcggta gtccgtcatg aactcttctt tagttgaatg gctttcaatc agttcaaccg
    26281 ctgcataggt ttcagcattc caaccgcccc caacgtccca ggcaccatta tcaacaggtc
    26341 ctacctgcat gatgcaaccg ttcccaacaa tgtgcgagaa aaaacctaat tctgggtctt
    26401 tccgccagtg ataatccgct tcattctgta cggttgaatg cggattccca gttgagtgtg
    26461 cgtgtacttg cctatatggt tgcacgccga cttgaggcaa atctgttctt aatttactca
    26521 cattaatttc catattctac tccttatcaa ttaaaacaac tcatttttta caatccagaa
    26581 ccagaaactc ctttatttct accttacaaa gaagacaatc ttagtcacga ttaggcttgt
    26641 agatagaacc tcaaaacgca ctattttgac actgtaaata ggactgacaa ggtctgcatt
    26701 ctatctacaa taacacccca gactaaaaag cttttcaaaa gtatattttt acagtctcta
    26761 tatgtccttt tcataaatac tatactttat tatatcatat aaaagaagtc aaaagtctgt
    26821 taaactattt tcaacaccaa actaaagaag agaacacaag ttttttcgat gttcactaga
    26881 ggaaatggat tttattcagt aaatccaact aggattgcac tttggttgcc aaaattgcct
    26941 ttccttcttt tatcaaggga tgacggaata gtgagaagta cagttgaact gtcatggcaa
    27001 cccagataag aggttcacaa aggataacac ccttatatcc tgcccaagga ataatcaaaa
    27061 ccacaaaaac gatttttccg attagttcaa taaagctaga aactagagga aggatcttct
    27121 gccccaagcc ctgcaagcaa ttgcgataaa tcaacaagag gctcaaaatg ggataaaagg
    27181 ctgaactgat ttgcagatag agacttccat tttctatcaa gtaaccatct gtcgaactag
    27241 ccaagaagga aaccaaggct ggactggcaa aaaagaggaa aatacaaaca aaaactgccc
    27301 aggatatact taaacgactg ccgattcgaa gaccttgaac aatgcggtca ggtcgcttag
    27361 ctcctagatt ctgagaagca aaggtcgtca ttgatgcaga aatagcggtc ataggaagaa
    27421 gggcaaaggt cataatgcgt cgagctgccg tctgggcact aataatcact gcaccaaatg
    27481 tattaacaga aaactgtaaa atcacactgc cgatagatac aattgaactc atcaagccca
    27541 tagccaaacc ttgctccaag agatccgcgt acaagctttt gtcccatttg aaatgtttaa
    27601 actgtggcaa gagttctggc acacttttac gaatataata aaagcagaga accgctgata
    27661 aaccttgcga aataatggta gcaagtcctg cggattgaac tcccagatgc aattgcgtaa
    27721 taaaatagag atccagaacc acattaacca aggcagagaa aatcagaaat cccagggctg
    27781 ctagactgtc accaatagac cgcaacaagc ctgcaaaaag attataagca aagctgacac
    27841 ctacacaggt cacaatcata gaaatatatt gataagattg aggaagaatt tctgcaggag
    27901 tatctaagta ttgcaagaga ggatacaagc caagaaagcc cagcaacata actagaatgc
    27961 tcaaaagagc acctaaaatc caggtggctg ctactgcttc cttgatttta gtgaaattcc
    28021 gagccccata ataacgagca atgacaatcc ccatgccatt gccaacacca agtgtaaagc
    28081 ctacaatcag gtcaaaaatc gctgtcgtcg ctcctactgc agccaaggat tcttgaccaa
    28141 gaaatcgtcc aacaatcaag acatcagcag tgttatagag ctgttgaaaa atatttgata
    28201 gcaagattgg aaaggtgaag cttaagagcg agggaagaat cggaccatgt atcaggtcca
    28261 ctgttcgttt tttattcata aagctattat atcagctttc cagaggagcg acaagaaaca
    28321 gcaaacttat atatagcgga atgaaataag gacagtcaaa tcgattttta acaatgtttt
    28381 agaagtagat gtgtactatt ctagtttcga tctattatag ttggttgagt ttggaatagt
    28441 acgctgtagc tgctaaaaca tttctagaaa ttaatttgac tttcctaata aagttgttca
    28501 tatcttattt caagctacta tatataatct aaaaacttga atcaaaaatc gaaaaagtag
    28561 cggatttctc cactgcttta acagcttatt cttcaatttc gatttcaagt tcatcgccta
    28621 agtcaagcgg aacttcttca ttcactgctt cttctttctt tggctcatct tttttgtttt
    28681 cagtatcttg ttctgaaact tcttctccat caatcaagcc aaatttagaa cggacttgct
    28741 tatcaatttc atcaaagatt tctgggtgct ctgccaagta tttcttagca ttctcagaac
    28801 cttgcccaat tttttcatct ttgtaagaat accaagcccc tgcttttttg ataatatcca
    28861 aatcgcttgc aatcttcaaa agctcaccag tcttagaaat tccttctccg tacataattt
    28921 caactacggc ttccttaaac ggtggagcta ccttattttt tacaacctta atcttagttt
    28981 ctttaccgac attggtttct ttttgatcac cagttccctt aatttgtgta ttaccacgaa
    29041 catccaagcg gactgaagca tagaatttca aagcacgtcc gcccggtgtt gtttctggat
    29101 ttccaaacat cactccaact ttttcacgca attggttgat aaaaatggca attgttttgg
    29161 ttttattgat agaggcgcca agtttacgca tggcctggct catcatacga gcctgcaaac
    29221 caacatggct atctccgata tctccatcaa tttccgcacg aggaacaagg gcagcaactg
    29281 agtcgactac gacaagatca actgcacctg agtcaatcaa ttttcccgca atctcaagac
    29341 cttgctctcc tgagtctggt tgagacaaga gcaattcgtc aatattgaca ccaagggccg
    29401 cagcataagc tggatcaagg gcatgttccg catcgataaa ggcagcaatc ccaccttctt
    29461 tttgcgcttg tgcaactgca tgaagggcaa ccgttgtctt accagatgac tctgggccat
    29521 agatttcgat gatacgtccc ttaggataac cacctgagcc aagggcaatg tcaagagcta
    29581 aagaacctga gctcatcact tgcacctttt gctccgcacg ttcacccaaa cgcatgattg
    29641 atcctttacc aaagtctttc tcaatcaatt taagagcatc attcaaggcc ttttcacgtt
    29701 ctgccccaaa tttttttgaa atttcttcta atttttttgg ttttttcgcc attctattct
    29761 cctacattct aatgatcctc agacctatct actattatat caaaagttag tcacttaata
    29821 aagccttgcg aactaggtta aaggcatgca taaccgcaat atgacgtaca tctgctcggc
    29881 ttctgcctcc aatattaacc ttgataacct cagttccttg ctcttgcgcc aagcctatga
    29941 agactgtccc aactgggtgt ccttctaggc tatctggtcc tgccactccg gtcaaactaa
    30001 ttccaaaatc agactgggtc ttgcttcgtg cctgctcagc catcttctga gctgtaaatt
    30061 cagacaccac accatgttct tccaaattct tggcaggaat atccaacatc cttgattttt
    30121 cctccaagct ataggtcaca aaaccaccct taaatatact tgaagctcca gaaaaattcg
    30181 ccacggtagc ttggaaaaga cctgccgtta aactctctgc agccgcgatg gttttccctt
    30241 gccttttcag ttcttctacc acaatgctgg ctaaactagt ttcttcccca taaccatagc
    30301 aaaagtctcg taaagaaatt ccttcgaaag tctggcagtc caagatttga ttttccaaga
    30361 tatccagcgc ttgattcgcc tcttcttgac tgctagcctt tgttgacaga cgtagagtga
    30421 cttctcctgt cttggcataa ggggccaagg taggatcgat ctgattatca attaaatcag
    30481 ccaaaatcgt aaccaactgg ctctcgccaa tcccaaagaa acgaagaact cgggaataca
    30541 gcttgctccc tgtcatcaac ttgggtagaa gttggtttaa gaccatgggt ttcaattcac
    30601 ttggcggacc tggaaggacg acataggtca ctccgtctac ttctaatttt cctccaacag
    30661 ccagtcctgt ttcgtttggc agtggaatcg ctccttctac aatttgagct tgtctttcgt
    30721 tattcggtgt tcgggcatag tctggtcgca gggcaaaaaa gatatccaac ttctcctgag
    30781 cctgaggatc aaagactaat gctttcccta aaaatttagc tagggtttgt ttggttaggt
    30841 cgtcctcagt tggccccaaa ccgcctgtca aaatcaccag actgctacgt tgactggcaa
    30901 tctcaagcaa agacaagaga cgaacttcat tgtctcctac agccgtctga aaatatacat
    30961 ctaccccaat ctcagctagt ttttccgaca aaaactgggc attggtgttg acaatctgtc
    31021 ctgtcaaaat ctctgttcca acagcaatga tttctgcttt catgtttcct cctacctatc
    31081 tattcgtatt tttttgaaaa aatcgcagga attttcctac gattgatttt tttatttgta
    31141 tcaaaagtta attatcttca tcaccaacag gtgctctgcc aaataaatct tcaaataaaa
    31201 ccgcattggt ttcaagctga gtaacttctt cttgtcccaa agaacgtcgg agtatatttt
    31261 gcatttccaa catatgtgct ctcgaaacaa tctggtaaga aacaccttga agtatctctc
    31321 cttcaccctg caactgctga gtttcaatgg ttttaaatga atctttatag cctagcaagt
    31381 tagggatact ttttgcagac aaatcaatat tggtctgcat attgtcactc aaagctttta
    31441 gaatctcttg ataatgacca acgctattta aactgagagc tttttccatg actttttgaa
    31501 taacttcacg ttgacgtttt tgacgaccat aatccccctc aggatcttgg taacgcattc
    31561 gtgcatagac tagggcttct tctcccccaa tatgttgctc cccaacaccg atagaaatag
    31621 tattaaattc ttcttggtca ctgatagaaa ttgggaaacc taggatatta ttgactgtaa
    31681 tacctcctac tgcatccact agtttttgca accctctcat attgaccatc acatagcgat
    31741 caatatggat attcatcatt ttttgaatgg tttctatagc aagctctgct ccaccatctg
    31801 catatgctga gttcagtttc gcttcatgag cctgaccatt ccctgattca atgcgcgtca
    31861 gaatatcccg ctctaaactc atcattgttg tttttttcgt tttaggattc actgtcatca
    31921 agatcatgct atcacttcta ccgacccaag tttcagttcg ttcaacattt ccggtgtcca
    31981 ctcccattaa cagaatggtt agaggttcag tcgcttcaat aaccttggtt tcttcaccga
    32041 tttttttata ggttttagct aaggtttctg tcccttgttg ataaatagta taagcaaaaa
    32101 cacctactcc tactacagtt acagaaagta aagctagcac cattccaata atttttttaa
    32161 ccatatttct actaacctat cagtttaccc atcaagtaaa catcgataaa tttcccttct
    32221 tctatatatg ccccacgctc ttggctacct tcaatgacaa agccatgctt ttgataaaga
    32281 tggactgctg cttgattacg agtttggaca gtcagttgga gacgacgcag aatgccactt
    32341 gcttgtgccc actctatcgc ttcttctagc aacaaacttc ccaagccatt attccaatat
    32401 ctttttccaa tcacaatgaa gagttctcca atatgacgga ctctcttacg ctggtcagct
    32461 gtaatattta caataccagc aattttgcca tttaagaatg caagtaaggt tatctgattg
    32521 tccgaactag cttgcttgtt gaggaatatt tccatctcct cactagtcaa gagaatacca
    32581 tctccgtcta ggctggtaaa gtctgtctcc aaactcacac gatttaaaaa ggccactaat
    32641 tcagctgcat ctttgggctc tgcttcccta atgagcaatt catactccat attgaagctc
    32701 ctctaacaat ttctcagcac gcaaaccctt tgcctgaaaa tttaaacggc gtccatctgc
    32761 ttcttttaga atttccaatt ctaaataagc atctggcaag gcatctccta agagattgcc
    32821 ccactcaata acagtcacgc cgccaccaaa gataaactca tccaagtcga tagaatcagc
    32881 atctccttca atacgataaa catctaggtg ataaagtgga agtcgacctt catactctct
    32941 cacgatagta taggtgggac ttttaatcat ttgagaaatc tgtaatcctt ttgcaagtcc
    33001 tttagtaaag gtcgttttac ctgcacccag ttctccagtt aagattaaaa catcattctt
    33061 tgctaataga tggcccaaac gctcccctaa ggcttgcaac tcttcttcat tttttgtgta
    33121 catactctta ttataccaaa aacttttctt ttgtgtctat tttcctacta aacttatcat
    33181 cataacatcc ataaaaaaca ggctttctct aaaagaaaat gagcgtaaca atgaccaata
    33241 caagatctcg gaaaatatga ccataaaagg aaacttcctt cttaaccgaa tttgggacaa
    33301 gataggctgc aaaaaacaag cccagtccaa tataaatcag aagtgagaca atggtcattg
    33361 gatttcttaa gaaaagaagt gttgctaaaa tagtcaccaa cactgtcttt tttctgtcta
    33421 gcatagcaag aaaatcgcgc acgtattttt tcaagggtaa aaaaatcagc aaatctagcc
    33481 caaataggaa aaagaaggat ggcaataaaa agtcaactaa ttcttgctgc agcgtatttt
    33541 tgatgaacaa gttatctgac aaaacaagaa cagctcctaa caaattaatt aagagtaaca
    33601 tactgtaaaa aagcttcaca gacttcttac tggctaggac actatggact tcttgcttac
    33661 gggtataaag ataatttact ccagcacaga ttcctgaaac gaaaaccatg cttccgatga
    33721 aaaaaactgt actttgttta aaggacaaga tgcattcctt ccataggaaa cagctactca
    33781 aactgatttg aattaaagct aacaaaaata agattctcat tgatttcatc ttctctctcc
    33841 cttcctacca atcattatac taggagaaaa gagagaactg tttctaatct tctcaaatgt
    33901 ctctttaaga cgctaaacaa acactagaga ctaatactca atgaaaatca aagatcaaac
    33961 taggtagcta gccacaggtt gctcaaaaca ctgttttgag attgcagata gagctgacgt
    34021 gatttgaaga gattttcgaa gaatataaat ttgaaatcat gaaaatccgt caaacgggtg
    34081 gttgttttgt ctcgcacctc acggagcgag acggactcag agtcacataa ttataaggct
    34141 gatagtatta atctaactat cagccttaca ggttatttaa cgtttcagaa aaactataat
    34201 gtcaagatta actaaacagt atctaattcc ttcaaataat tttctatctt catcaacatt
    34261 aaaggattgt tataaatctt acataactct cttgcttcta tataataatt tttgacttgt
    34321 tctctgtcta gaaatttggc tccagcattt cctacaagaa taagtagagg agccaattgg
    34381 tagcttgtct gtctttgttt acagagttca atcgtttcaa gagcttcttg gatggcttca
    34441 ttatattttt cctttgatac taggtagtga gcgtagttgt aacgaactct gatgtagcca
    34501 aataaaaact cttgatggtc caaatttttt gtctgataca actctattaa atgagagtag
    34561 tttgcctcat attcttgttc acgacccact aaggaataga aattagatag agtattcaac
    34621 gcctttaaat aaatcagagt atttgaagag acttttaata atatattttc caatgacgaa
    34681 attgcctcac acttactgtc atattgatag aagtcaatta tagatttaat ccattcaagg
    34741 taagttcggt cttctaatgt tagaaaagtg cttcgttcta cctctatttt ataaagatat
    34801 tctaaatcgt cataatttct gtcatctaat aggcgagcag atagatgttt gaaattagag
    34861 aggttagact taacttcgat ttgttcattg aaaaagtaat ccaaagggac ttcaagtcgt
    34921 tgagagagtt tgaataacaa gtctgcggag ggaataaaat gacctctttc aattttacta
    34981 atctggcttt gttcacaaat tccttctgca agagtttgtt gggagagtct caactctttt
    35041 cttttcaatc tgaatttctc tgcgagtgta ttcattaaag ataataaacc ttcctatttg
    35101 cttaa
//
LOCUS       DAVLAQ010000018        35037 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000018 DAVLAQ010000000
VERSION     DAVLAQ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35037
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.018"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(1..533)
                     /locus_tag="VXB71_000878"
                     /pseudo
     CDS             complement(1..533)
                     /locus_tag="VXB71_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(609..821)
                     /locus_tag="VXB71_000879"
     CDS             complement(609..821)
                     /locus_tag="VXB71_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0451015.1"
                     /translation="MIQPLLHADETSYRVLENDSHLTYYWTFLSGKAENQAITLYHHD
                     QRRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(830..1135)
                     /locus_tag="VXB71_000880"
     CDS             complement(830..1135)
                     /locus_tag="VXB71_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEV0451016.1"
                     /translation="MFPVETEEITYKRKKSKGKRQAILAQFDSEEVHHQVEESICPDC
                     QDDLKEIGASLQRQELVFIPAQLKRVDHIQHAYKCQTCSKNNPSDKIVKAPIPKAPL"
     gene            complement(1122..1316)
                     /locus_tag="VXB71_000881"
     CDS             complement(1122..1316)
                     /locus_tag="VXB71_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0451017.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(1486..1836)
                     /gene="tnpB"
                     /locus_tag="VXB71_000882"
     CDS             complement(1486..1836)
                     /gene="tnpB"
                     /locus_tag="VXB71_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0451018.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1817..2002)
                     /locus_tag="VXB71_000883"
                     /pseudo
     CDS             complement(1817..2002)
                     /locus_tag="VXB71_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2306..3868)
                     /gene="guaA"
                     /locus_tag="VXB71_000884"
     CDS             complement(2306..3868)
                     /gene="guaA"
                     /locus_tag="VXB71_000884"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0451019.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CLYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4010..4708
                     /locus_tag="VXB71_000885"
     CDS             4010..4708
                     /locus_tag="VXB71_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0451020.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4751..5647)
                     /locus_tag="VXB71_000886"
     CDS             complement(4751..5647)
                     /locus_tag="VXB71_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0451021.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5656..6591)
                     /locus_tag="VXB71_000887"
     CDS             complement(5656..6591)
                     /locus_tag="VXB71_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0451022.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6588..7313)
                     /locus_tag="VXB71_000888"
     CDS             complement(6588..7313)
                     /locus_tag="VXB71_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0451023.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7397..8032)
                     /locus_tag="VXB71_000889"
     CDS             complement(7397..8032)
                     /locus_tag="VXB71_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0451024.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8034..8861)
                     /locus_tag="VXB71_000890"
     CDS             complement(8034..8861)
                     /locus_tag="VXB71_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0451025.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8883..9218)
                     /locus_tag="VXB71_000891"
     CDS             complement(8883..9218)
                     /locus_tag="VXB71_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0451026.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9219..9935)
                     /locus_tag="VXB71_000892"
     CDS             complement(9219..9935)
                     /locus_tag="VXB71_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV0451027.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            10448..11059
                     /locus_tag="VXB71_000893"
     CDS             10448..11059
                     /locus_tag="VXB71_000893"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0451028.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11104..11832
                     /gene="rlmB"
                     /locus_tag="VXB71_000894"
     CDS             11104..11832
                     /gene="rlmB"
                     /locus_tag="VXB71_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0451029.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11871..12782)
                     /gene="trxB"
                     /locus_tag="VXB71_000895"
     CDS             complement(11871..12782)
                     /gene="trxB"
                     /locus_tag="VXB71_000895"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0451030.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12848..13072)
                     /locus_tag="VXB71_000896"
     CDS             complement(12848..13072)
                     /locus_tag="VXB71_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0451031.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13150..13893)
                     /locus_tag="VXB71_000897"
     CDS             complement(13150..13893)
                     /locus_tag="VXB71_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0451032.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13893..14693)
                     /locus_tag="VXB71_000898"
     CDS             complement(13893..14693)
                     /locus_tag="VXB71_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0451033.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14851..15207)
                     /locus_tag="VXB71_000899"
     CDS             complement(14851..15207)
                     /locus_tag="VXB71_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0451034.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15220..15732)
                     /locus_tag="VXB71_000900"
     CDS             complement(15220..15732)
                     /locus_tag="VXB71_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0451035.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15732..16226)
                     /locus_tag="VXB71_000901"
     CDS             complement(15732..16226)
                     /locus_tag="VXB71_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451036.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16361..16807
                     /locus_tag="VXB71_000902"
     CDS             16361..16807
                     /locus_tag="VXB71_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0451037.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16804..17451
                     /locus_tag="VXB71_000903"
     CDS             16804..17451
                     /locus_tag="VXB71_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0451038.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17472..18053)
                     /gene="pdxT"
                     /locus_tag="VXB71_000904"
     CDS             complement(17472..18053)
                     /gene="pdxT"
                     /locus_tag="VXB71_000904"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0451039.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18054..18929)
                     /gene="pdxS"
                     /locus_tag="VXB71_000905"
     CDS             complement(18054..18929)
                     /gene="pdxS"
                     /locus_tag="VXB71_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0451040.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19081..20460)
                     /locus_tag="VXB71_000906"
     CDS             complement(19081..20460)
                     /locus_tag="VXB71_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0451041.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20754..21677
                     /locus_tag="VXB71_000907"
     CDS             20754..21677
                     /locus_tag="VXB71_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0451042.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21737..22342
                     /locus_tag="VXB71_000908"
     CDS             21737..22342
                     /locus_tag="VXB71_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0451043.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22361..23605
                     /locus_tag="VXB71_000909"
     CDS             22361..23605
                     /locus_tag="VXB71_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0451044.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSS
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23828..24085)
                     /locus_tag="VXB71_000910"
     CDS             complement(23828..24085)
                     /locus_tag="VXB71_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0451045.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24127..26163)
                     /locus_tag="VXB71_000911"
     CDS             complement(24127..26163)
                     /locus_tag="VXB71_000911"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0451046.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26423..27340)
                     /gene="glyQ"
                     /locus_tag="VXB71_000912"
     CDS             complement(26423..27340)
                     /gene="glyQ"
                     /locus_tag="VXB71_000912"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0451047.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27359..28120)
                     /locus_tag="VXB71_000913"
     CDS             complement(27359..28120)
                     /locus_tag="VXB71_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0451048.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28393..29235)
                     /locus_tag="VXB71_000914"
     CDS             complement(28393..29235)
                     /locus_tag="VXB71_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0451049.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLESLKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(29350..30741)
                     /locus_tag="VXB71_000915"
     CDS             complement(29350..30741)
                     /locus_tag="VXB71_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0451050.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(30976..31353)
                     /locus_tag="VXB71_000916"
     CDS             complement(30976..31353)
                     /locus_tag="VXB71_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0451051.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31568..32545
                     /locus_tag="VXB71_000917"
     CDS             31568..32545
                     /locus_tag="VXB71_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0451052.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32542..33624
                     /locus_tag="VXB71_000918"
     CDS             32542..33624
                     /locus_tag="VXB71_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0451053.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTINLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33688..34718)
                     /locus_tag="VXB71_000919"
                     /pseudo
     CDS             complement(33688..34718)
                     /locus_tag="VXB71_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10395 a         7794 c         6281 g        10567 t
ORIGIN      
        1 tcataataat agctcttgct ttagctcctt caaaactttg agaaaataac caccctcgct
       61 tttttaaact gagcttaggc taaaagagtc cactggactc ttttactccg tcccataacc
      121 aatgatttaa tggcgcattc agctagatta ttggaaagga ccagatgtcc gtctttcaaa
      181 atagtcttaa aggtttcttt atacttgagg ctatacttga ggctgtattc aattgccctt
      241 cctagttttg aacccgataa aactgactga cgccggcacc aagcaaagaa atcttccatt
      301 aggggttgga gatgttcttg acgtttctgt agtcgttcat cagctggcaa agcctcccag
      361 tttctttcca aggaaaataa ctgattacaa taagctaaac ctttagctcc taaggatgat
      421 ttattcgctt gcttgggggt cgcttcaaaa aacttccttc tcacatgtac ccaacatcca
      481 acaagttcag cttcttccag ttgacaataa gcttctagcg gttcgcagtt taccaagctt
      541 agcgtcgcct tgctcctaaa ccttggactg ctatcgcata ggcagaacta gaggactaaa
      601 gtcctaagtt actgccgcaa catatcacaa tgcacatagc cagaataatc tcctaggaat
      661 tcttgcacta ccgaaccact ccgacgctga tcatggtggt acagcgtgat tgcttgattc
      721 tcagctttcc cagacaaaaa ggtccaatag taggtcagat ggctatcatt ctctagaacc
      781 cgataggagg tttcatctgc atgaagtaag ggctgaatca atagtctcgt tataaagggg
      841 ctttaggaat aggagctttt acaattttat cacttggatt attcttactg catgtttggc
      901 atttgtaagc gtgttggata tgatccactc tttttaattg cgcaggaata aagaccaatt
      961 cttgtcgttg aaggctcgct ccaatctctt ttaaatcgtc ctgacaatca gggcaaatgc
     1021 tctcttctac ttgatgatga acttcttctg aatcaaattg ggcaagaata gcttgacgtt
     1081 tccctttaga tttcttacgt ttgtaggtaa tttcctctgt ttcaactggg aacatctcca
     1141 tctttctcag atggagactc ttcctcaaaa aggttgagtt gtccaaaagg gcaaacactt
     1201 ttctcagagg attttccaga gagcttttgc gttagataag ccacttgttc acacagaagg
     1261 gaaagttcat tagtgagact atcaattata gcactctgtt gttgaatgat tttcaatctt
     1321 ctcccataga ctttcctcct tatttcctaa ctttattata tagtgtattg aatctataac
     1381 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagatgt
     1441 tcatatctta tttcaattca ctatactaaa aagaaagtcc tcatttcaat agaaatcacg
     1501 actttctgat aaatttattt tgggagtgat agaaaagccc ttcataagcc aatctacttg
     1561 ttcaggtgtg agagctttga catccttttc tgtactgggc caagtcagtc tgccgttctc
     1621 aaagcgttta tatagtagcc aaaatccttg accatcccag taaagggctt taaagcggtc
     1681 tttacgtcca ccacaaaaga gaaaaacttg accggagaaa ggatccaatt caaagtgggt
     1741 tttaaccaga taagccagtg aatcgattcc ttgtctcata tcagtcttcc cacacacgag
     1801 atagacctgc cctaggctag atagatgaat tgtcatagag caacacctta tccaaaagct
     1861 gttctaccat ttcgagattg agagattgaa aaaaacttac ttcaagcttg ccaatacgaa
     1921 tttaaagcag aatatcattt ctctttttag aatcaaaagg acgagattgt ggaatctcta
     1981 caggaacaat aggttgtggc attaaaatat cctccaatag ttttacttta ctaatagtat
     2041 acaggaggaa ctccatgaat gatagatacc ttgttatgac gcgcttacta tattagaaag
     2101 ttggctctct aattaaatta attctcatta tatatatcaa aagaccgcag tttgaaaact
     2161 acggtctaat tttttgtcca aatgtaaatc acttggaact attattcaat ttattctttt
     2221 tagtaaatgt tcccgtttta atcccagtta cagtttttaa tcctctgtaa ccgttgattt
     2281 tacaaagctt ttaatttttt tgcgattact cccactcaac tgttgcaggt ggtttacttg
     2341 taatatcgta gacgatacgg ttaacatgat ccacttcatt tacgatacgt actgagattt
     2401 tttgaagtac ttcccatgga attttggcaa aatcagcagt cataccatcg atagaagtga
     2461 tagcacggat tgcaatcgtg tagtcatacg tacgaccgtc acccataaca ccgactgaac
     2521 gaacgcctgt gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca gctttagcga
     2581 tttcttcacg aagaatagcg tctgattcac gaacggtttc aagtttctct tcagtgattt
     2641 cacccatgac acggatagca agtcctggtc ctgggaatgg ttggcgccat acgatatggt
     2701 ctggcatacc aagctctgta ccaagagcac gaacttcatc cttgtaaaga gtattgagtg
     2761 gttcaatcaa ttcaaactgc atatcttctg gaagaccacc tacgttgtgg tgtgacttga
     2821 tagtttgagc tgtatccgta ccagactcga taacatctgt atataaagta ccttgagcaa
     2881 ggaatttcac atctttgagc ttgcttgctt cgtcatcgaa tacatagaca aactcgttac
     2941 cgatgatttt acgtttttgt tcaggatcag aaacgccagc aagtttgtca aggaaacgtt
     3001 tagcagcgtc tgctttgacg atattcaaac caaacttacc accgagcatg tccataactt
     3061 gatcagcttc gcctttacga agaagaccgt ggtctacgaa gatacagatc aattgatcgc
     3121 caatcgcttt ttggagaaga accccaacga cagatgagtc aacaccacct gatagaccaa
     3181 gaaggacacg tttatcaccg acggtttcac gaattttttt gatctgcatg tcaatgaaat
     3241 tatccattga ccagtcacct ttagccttac aaatgttaag ggcaaagtta cgaaggatat
     3301 catttccgta tacagaatga cgaacttctg ggtggaattg gataccgtaa atgtgtttat
     3361 ctgggttttc gatggctgcg tataggcagt cagctgatgt acctgtacga acaaagtcag
     3421 caggaatctc agtaaccgca tcaccatggc tcatcaaaac agtctgttca tcaggtgttg
     3481 attcaaaaag cgctgatggt gtgtgagtta gggttgattg accgtattca cgatttccag
     3541 catcacctgc aggaacaact tttcctccaa gtttatgggt caataactgc ataccataac
     3601 agattcccaa aattggaatt ccgagttcga agatttctgg gtcaatatca aatgaaccat
     3661 cttcatatac agaatttgga ccacctgata gaataattcc tacaggattg acttcacgaa
     3721 cttcagcagc tgaaatttta tggcttttta gttctgaaaa aacaccaatc tcacggatac
     3781 ggcgtgaaat cagctggttg tactggctac catagtccaa tacgatgatt ttttctacat
     3841 cttgcaaatc agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa tatcttttct
     3901 caatattcta tcacaaataa gggcgaatta ccaactaaac aaggcgaagt ttgacttttt
     3961 ctagtttatt ggggtacaat agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc
     4021 ttatatgaaa atccatgatc agataaaaaa ggatattgac gagcaccgtt gggctattgg
     4081 tgagaggctt cccagtgaaa gagatttagc tgagcagttt gcggtcagtc gcatgaccct
     4141 ccgccaagcc gtatctctat tagtcgaaga aggcgtctta gagcgccgtg taggaagcgg
     4201 cacctttgtt tccagtactc gagtacaaga aaagatgcga gggacaacca gttttactga
     4261 aattgtcaaa tcccaaggta aagttccctc tagccagctc atttcctaca aaaaaaccat
     4321 tcccaatgag caagaagttg ccaagctagg aatttttcca acggacaata ttatccgaat
     4381 ggagcgggtc cgctatgccg accaagttcc cctagtttat gaagttgctt ctattcctga
     4441 aaaattcatt aaggacttta aaaaagaaga aatcaccagt catttcttcc aaaccttgca
     4501 aaaacatggc tatcgtatcg gcaaatctca acagaccatc tatgctcgcc ttgctaaaga
     4561 aaagattgcc cactatttgg aagttgaaaa aggacatgct attcttggat tgacccaggt
     4621 ttcctaccta gaagatggta ctgcttttga atacgtaaaa agtcaatatg taggcgaacg
     4681 ctttgaattt tatcttgaaa ataattagat taccacgcaa aaactctctg tcacggacaa
     4741 agagtctttt ttatttttct aagaataaat ctttcaaaga aatcaaagtt acagcaaaca
     4801 atatcattgc cataccaata aaatcaatgg gataaaattg ttcattcatt attaagaagg
     4861 caaagaaaac cgccgatatt ggctcaattg aagccaacaa gcttgacttg accggtccta
     4921 tcagactggc tcctttaagg aaagctgtat aggcaaagac agtcccgata aggataatgc
     4981 ctgcaaacgc aaggagaaaa tcaagactag tcgggatatc ggcctgtaga acccctgtaa
     5041 aaggaagggc gaccaaacct gctatgacca tccccacacc aatgaccaag ctgctccccc
     5101 actttttaat caaggctatg ggtaaaatga tatacaaagc ataagtcaag gcagaaaaga
     5161 gaccccagaa caggccagca ggtgtcatgg ataactggtc caactgccca tgtgttgcga
     5221 tcaggaaggt tcctccgatg gcgaatatga tggaaactat ctctcccagt gtcggtgcca
     5281 ccctatcctt gatacagcta taaattaaaa ttccgacagg acaaacatac tgaagcaccg
     5341 tcgctgttcc cgcattggtc tcctgaatag cagacagata ggcgaattgg ttgagaaaaa
     5401 gaccaatcag agcaaaaata agaagagaca gcaaactctt tctatccttt aaaaagacca
     5461 gtattttatc ctttgcagta gcataagcca agagcatgag aattccacca gcgattaaaa
     5521 gacgcaagtt ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat tggccactcg
     5581 ttcctgacaa cccccaagca ataccagcca caactgttag taaagtccct tttaaactat
     5641 ttgacatgtc tctccttact cttctttgcg aatcaagttc atcacttgat tgcggtctaa
     5701 tatccattga gctctctcgt ccttttcata ggtacgattc gataggaaaa tagtggcttc
     5761 ttgcttctga cgattccaca tgataaaggt acctgtatag cccgtatggt ctagccaatc
     5821 tccttccaaa ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa aattttgatt
     5881 taagtctctt gcaaaatcat ctgctaaata gtgttctaaa aagatttgta aatcctttat
     5941 agtcgaaaat aaaccagcac tcccagcatg tctacccagg agacgagcct tgggatcatg
     6001 cactatgcct gcctctacac ctctaactgt tggaacagca agctcaactg gcccaaactt
     6061 ggtttccgtc attccccaag gtttccagac ttgatccttt aaaatcacat ccaaatcttg
     6121 attaaaaatt ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg aataaagaaa
     6181 ggctggctga cttcgtctgt tgagatgaaa catcgcttcc tttaattcag gggctgttaa
     6241 aagatcacga ttaggaataa aaggatcaag gtctgttgca tgagtcaaga gctggcgaat
     6301 agtgatgtct ggataatcac tctcaggtaa aaaatctatt accagtctat caatatctaa
     6361 ttgacctatt tcccacaaga aggtacaaac tgtgccaacc ccaacaacct tgctgacact
     6421 agctaggtca taaactagtc ctgcctcagt ctgcaagcca tgctctgggt cactctggcc
     6481 taaatagaac tctgtccatt gattgtcctt aaaatacgca aaagaggctc cgggataaat
     6541 tcctgcctcg atttgttctt ctattttttt aataatcttg gtccacttca tacttcttca
     6601 aaccacaatt caacattatt tctatcttta caaaggaaga atttttcaga cttaggaata
     6661 aaatattcag tagactcaaa cttctggcga agacttgcta tgtctaattc attgaccaag
     6721 aacttgagca tagataagtc ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga
     6781 gctggaataa aatcaaggga tgccccaatt tcagatgatt ccaagaaact ttcgatatca
     6841 gttgggagat gtaattccat agaaatctca aatttactta aagaaattga tgccaaatct
     6901 gtttgaaatt caggcttttc tcctacttct actagacttg ctatgtcatc ttccgcatga
     6961 atcaaaatca aatcatcttc tggtgagaaa atttcaaaag cgtagccatt ttgaccttta
     7021 tataatcgat gaatcgaatc tgttttagat aagattcctt caatttctaa gggattttcc
     7081 accttgacaa tcaatctagc tagttttttt cttccctcta ccttacgagt acgcatactg
     7141 ggagcttctt ctaaaaccag cttttcaaga cccgtttggt cacctagtga cagaaaggcc
     7201 gattcttcta acaaggcctt cattccaagg gtttcaatat aaaatgtttc atttaatttt
     7261 ctattattag cttttaaagt aggaataatc cgtacaatct gatttacatt cataaattcc
     7321 tccgtcactt tttattttaa aggattttag aattttttac aagatattat gctcaaattt
     7381 aacattattt agctatttag taaagatagt ctttcaagga ttttgacaaa gcctgataac
     7441 cagcaatact gaggtgcagt ccatcagttg tatattcttt tttgagttgg cctgcttggt
     7501 ctgtcaaaca atcaaatact ggcacaaatt ccacctgcat ataggcagat gcaagctctt
     7561 gataggcttg attccagttc tgaatttttt cattcgagcg gatatagact gcctgctggt
     7621 actcctctct ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc aatggataat
     7681 cgcgagcaac ggattgaatg atagcttcga gattattgag agcctcattc acaggaacat
     7741 cctttccgat atcatttgtc ccaatcagaa gaaaaatttt atctactgct ccaccatata
     7801 gatgagcatc aaggttctct agtaacagtc ctgtctgata gccacgaatt cctcgattga
     7861 caatcgtctt tgaagtccca aatagctcct gtagaggata atactcgaca atggaatccc
     7921 caataaaaag aatgtttggt tctacaacag aaatgtgatt taggtgacga tacttagttt
     7981 gaattttttc ttgttccttt aggagccaat tttctaataa ctgtactgcc acttcattct
     8041 cctttttcta accagttttc caagacttga taaactcctc cttggctgtt ggctggtgct
     8101 agagcagtcg ccacagcttt ggctttctca tcagcatttt ccatcgcata ggcaattcca
     8161 gccatttcaa gcatttcaac atcattttca ctatcaccaa aagccatgat ttcttgggat
     8221 ttcaagtccc agcgcttgag taattcctcc aagccccatg ctttatgaat cccagcttgg
     8281 aggatatcaa tgcaaccata gccactggat acagctcgga cacggccatc aaagagagca
     8341 ttgatttctt ccaaaaccga actcaaacgt tcctcaccaa caaccatgct catcttgagc
     8401 acaccaccaa agaggtcaga tgttaattca tccacaaatt gcatccgttg gtagaatttt
     8461 tcaatcattt ctggagtcat aaaactttca agatctgtaa aaatcgtacc ttccttgaca
     8521 aaatcaccct tcatccccgt tacaacaaac tggtcctgac acgctcgacc cttgaaatga
     8581 gtcaaagcct tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt
     8641 tcaaaaatac gagcgccatt agcaacaacc agaaccactc gatccaccaa gggactcagt
     8701 agttgtctca tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat gcccctttga
     8761 tccaactgat ctaaaatctt ttccaatcgt gggagatcaa gctgacctct agcatccagc
     8821 aaggtcccat ccatatctgt cgcaattacc ttaatcatca tttactttcc tctggattca
     8881 agctaatacc acttcaatcc cacatgttca ttcatttctt tataggctgt atcaattcgt
     8941 tccttagtcg cttcatctaa ctggtcacga tgactgccat cctctataaa atcttccaaa
     9001 atataagttt ggtaatgata caagggatat ccttctggtg aaaaggttcc ctttggtgtt
     9061 cgattgaccc aagtaggatg agctttagct gttccgatag ttgtttttcc atccttcttc
     9121 ttgatggtga catccatgag aacaccacgt tcagtccact tagcattctc ttcatctccc
     9181 atagattcaa ttcgttgatt ggaaatgaag ttccccattt aatagacaat gagcttttta
     9241 tctccatctt tttccaccgt ttcagatggt tcaacaacgt gaggatgccc tccaaagata
     9301 atatccgctc cccaatcaat catcttgtga taaagagctt tttgttcttc agttggttcc
     9361 aatcgatact caacacccat ctgaggcatg ataatggtga tatctgcttc cttctctgcc
     9421 cgttcaactt cagcctttat cttatcttcg tttaaatctg aaagataacg attatagtct
     9481 tcctgagaaa tatactgctc aattccattg aaaccatagg aataggctaa caatgcaacc
     9541 ttgatagcat tcacttcctt aatgaccagc ggagcctgag cacgtggttc gtgcgtataa
     9601 actccgattg gagtgattcc agctttctca ataatatcgg ccattgaaat aactccctca
     9661 atttgcgaat ccaaaatatg attatgagct aaatccagca catgataacc tgcctcctta
     9721 atagcatcca taacttcaac aggagcatta aagagaagat aacccgctaa ataatgatcc
     9781 ttattaatgg ttccttcaaa atcaccaata gctaaatctg cttgcttgag ccaaggagtc
     9841 acatactcaa aattttcatg aaagtcatag gtaccgtctt cttttttagc tgaaaagaaa
     9901 agtccatcgt ggtagagcaa atccccgtgg gccataattc tggcagtttt ttcctcttcc
     9961 tactcctgag acttttgctt agtcccctct tgagaaatag tatctcgttt ttgactagtc
    10021 aagggattcc ttggaagctt tcaaacaaca agaccaagcc cattgataaa ccaactgcta
    10081 gcaagagtat cgccacaaat cccttattgc tccacttgcg ataactccta aaaagtttac
    10141 caagcccttc ataaaacgaa aagctgaacc accctgattt cgattttgtc ttctttgtat
    10201 cttcgttctc cctactttct tatgcaagcc ttttcttttt attatatcac agataagtat
    10261 ttctttcaca attgaattga acttcctatc tattttctat aaatcctaaa tgccataatg
    10321 ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa tgaactaatc cacagtggct
    10381 tattccaagt ataccacttg ggctttggca gtagctaact gcactaaaca taatataagg
    10441 agagaaaatg tctgcaatag aacgtattac aaaagctgct cacttaattg atatgaacga
    10501 tattatccgt gaagggaatc ctactctacg cacggttgct gaggaagtca ctttccccct
    10561 atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa ttccttaaac attcccaaga
    10621 tcctgtcatg gctgaaaaaa tgggactccg cggtggtgtt ggactggctg ctccccagtt
    10681 agatatctca aaacgcatta tcgctgtttt ggtacctaat attgttgaag aaggcgaaac
    10741 tccacaggaa gcctacgatt tggaagccat tatgtacaat ccaaaaatcg tctctcactc
    10801 tgttcaagat gctgctcttg gcgaaggaga aggttgcctg tctgttgacc gtaacgtgcc
    10861 tggctatgtt gttcgccatg cccgcgttac tgttgactac tttgacaaag atggagaaaa
    10921 acaccgtatc aaactcaaag gctacaactc cattgttgtt cagcatgaaa ttgaccacat
    10981 taacggtatc atgttttacg atcgcatcaa tgaaaaagac ccatttgcag ttaaagatgg
    11041 tttactgatt cttgaataaa gaaaatcccg ttgcaagacg gggttttgtg ttataataga
    11101 ggcatgaaaa caaatgatat tgtctatggt gtccacgctg ttaccgaagc cctccttgca
    11161 aatacaggaa acaaactcta cctccaagaa gatctccgag gtaagaatgt tgagaaagtc
    11221 aaggaactag ctacagaaaa gaaggtgtcc atttcttgga catcaaaaaa atctctctct
    11281 gagattactg aaggtgctgt tcatcaaggt tttgttctac gagtgtctga atttgcctat
    11341 agcgagctag attacatcct tgcaaaaaca cgccaagaag aaaatccact tctattgatt
    11401 ctagatggtc taaccgatcc ccataatctg ggttctatct tgcgaacagc cgatgcgacc
    11461 aatgtttcag gtgtcatcat tcccaagcac cgtactgtcg gagtaactcc tgtcgttgcc
    11521 aaaacagcca caggtgctat tgaacacgtt ccaattgccc gagtgaccaa cctcagtcaa
    11581 accttagata aacttaagga tgaaggtttc tggacctttg gaacggatat gaacggtact
    11641 ccttgccaca agtggaatac aaaagggaaa atcgccctca tcattggaaa tgaaggaaaa
    11701 ggtatctcta gcaacatcaa aaaacaggtc gatgaaatga ttaccattcc gatgaatgga
    11761 catgttcaaa gccttaatgc cagtgttgct gcggccattc tcatgtacga agttttccga
    11821 aatagactat aaaaaagttt ccagtcatct gattggaaac ttttttatga ttaactatgt
    11881 tctgtaatga atttataggc ttcttgacca gcgatagctc catctccaac cgctgttgtt
    11941 acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa agataccgtc gactgcagtt
    12001 ttcatgtggt tatctgtcac aatccatcct gcctgatctt ggatattcaa ttctttaaca
    12061 aaatcgctaa gagggtccaa accaacatag ataaagacac caccgaaggc ttgttctgtc
    12121 acttgacctg ttttcacatt ttcaaatacg actgattcta ctcggttttc acccttgatt
    12181 tcccttacta cagaatccca gataaagctg attttttcat tcgcaaaggc gcgatcttgt
    12241 aaaacctttt gggcacgaag ttggtcacga cggtgaacaa tggtaacagt cttagcaaaa
    12301 cgagtcaaga agagggcttc ttcaacagct gaatctccac caccaactac caataaatct
    12361 tggtcacgga agaaagcacc atcacacaca gcacagtaag aaacaccacg actgttcagt
    12421 tcttcttctc caggcactcc caaaggacgg tgtttagaac cagttgctac gataactgta
    12481 cgtgtttcat atgtttggtc atcagtcatc actttcttaa aatcaccatg gtcttcgaca
    12541 ttttcaacat aaccataaat gtgctcaaca ccaagatttt caagtggttc aaacatcttt
    12601 tcagccaatt caggtccact aatattagcg tatcctgggt aattttcgat atcagatgta
    12661 ttattcatct gaccacctgg cagaccacct tcaatcaaag ctacttttag attgcttcga
    12721 gcagcataca aggccgcagt catccctgca ggtccagcac cgataataat agtatcgtac
    12781 atatagattc cttctttctt gttgtaacta tctttattct aactctttct tgtcaatcac
    12841 gcaaggatta tgccttgaaa acaagaatta aactcataac cgcaaaggat aatactggga
    12901 caaccaagac tccaatcata atcatatcat agagatgggc ttggcgagcc ctggctgtct
    12961 tatcaactcc cgacatggct ctcagaccaa tccaaatccc taaaaaaatc agaacaagga
    13021 tggtggtcaa gatcaaactc tcgaaatata aagaaaatag ttgcagtagc atgatttctc
    13081 tcatttctat cttttttaaa gagtaaactc agctagtcca actaactgag ttttccttta
    13141 tctattatat caaatataag tccgtttgta actagcgaag aattcttttg tccgctcttc
    13201 tttaggggtg tggataatct catccggagt tccagactcg atgattttcc ccttatctaa
    13261 gaagagaatt ttatccgcaa cttgggctac aaaggacatg tcatgactga ccaaaatcat
    13321 ggtctgacct gacttagcag catctgcaat agacttttct acttcaccga ccaattctgg
    13381 gtcaagggct gaagttggtt cgtctaagag caaaacatct ggtttcatag caagcgcacg
    13441 cgctagggca acccgttgct tctgtccacc tgataaatgg cgaggataat ggttttcacg
    13501 gtccgaaagc ccaaccttag ccaactcttc cttggcaatc ttagtcgctt cttggtcaga
    13561 taatttcttg acaacaacca agccttcttt cacattatca agtgctgttc ggcgttcaaa
    13621 taaattaaac tgttggaaaa ccatagacaa cttacggcgt agggcaagga tttcttcttg
    13681 agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga atagagccac tgtcaggtgt
    13741 ttcaagataa ttgagactgc gaagaaaggt tgattttcca gctcctgaag aaccaatcaa
    13801 ggctacgact tctccttttt gaatatccaa gttcagatga tccaagacag tctgtcctga
    13861 aaaggatttg cttaaattcg aaatcttaat cattaacgaa ggtctccttt cacatctgtt
    13921 tgcactgtat caggtgcaga aatagccatt tttctctcga tgaaacgacc gaggctttca
    13981 attccgatat tgactaccca ataaacaagg gcaacggaga tgaagcgttc aaaatagcga
    14041 taatcagctc cacctagaat ctgagcttgg gcaaagactt ccacaacacc cgcactaaaa
    14101 gctagagatg ttcccttggt caaaccgatg agggaattaa tcaaggttgg agtagctacc
    14161 accgctgcat taggaataat cactcgtcga taaacttgcg ctcgggtcat acccagactg
    14221 cgtgccgcct caatctcacc aggattaact gagagaatgg ctgcacgaat ggtttcacta
    14281 gcataagctg cctcattaaa ggcaaaagcg acaatcgcaa aagctgcagc tggaatcgca
    14341 ttgatattga gaccagttcc ccattgctga ttgagggctt tcaaagccaa agggattccg
    14401 tagtaggtca acatgagttg caccaaaatc ggtgtccctt ttaagaaact aacaaagaag
    14461 gcctgcaagg gatataaaat cttgacacga ttgatcttca caatggcaaa aagaagcgcc
    14521 aaaaccaagc caaaaagggc accaccaatt gtcaacataa ttgttgttgg aagttgttgg
    14581 acaattctag ggattccatc aaagaccgaa cgtaggctaa acagcttgcc atccggaatc
    14641 aattgcatca agttttggta ccaatctgat gctaaaatcg ttgtaacatt cataaaaaca
    14701 tcctcttctg ataatgattc attctaccat gcttctgccg tcaatgaaat tatttgctac
    14761 ggtcagatac agactttgtc tacctactag tttatcatac tttgaaacag ggaagttata
    14821 tattttatct atcaaagaga tagataaaaa ctatttcagt cccagttctt cataagattt
    14881 tcgataaccg atttgcttaa cagttccatt ttctactaaa atgggccgtt ttaacaacat
    14941 accgtcactt gctagcaact cagccgcttc ttggtttgac aaacttccta ccttatcttt
    15001 tagccctaat tcacggtatt tgataccact ggtgttgaaa aattgcttca attcaaatcc
    15061 tgaggtttct agccaattca aaatgacttc ttggctaggt gtttcttcca cgatatggac
    15121 ggctttatag tccacaccta attgatttaa ttcttgtttt gcttttttac aagttgaaca
    15181 tttggggtat tcgataaatt ctaacatgtg cttctccttc tatttgttta tatctttaaa
    15241 atctacgcct tcatgctcca agagccaagc tttcttttcc actcctgcag catagcctgt
    15301 cagacgcttg cctgctccca acacacgatg acaaggtact aggatagacc aaggattgcg
    15361 tcccactgct ccaccaattg cttgagcaga agccacttgc aggtcttgag caatttgtcc
    15421 ataggtcact gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc tcttttcaaa
    15481 attcgttccg attggcgcca agagcaagtt ggataaatcc tgaggcttgc ctttaaagta
    15541 atcatctaag caagcaataa ctgggtctaa aataggatga ctaacaactt cttctatcgt
    15601 ttcatctcct agtcccctct caaaatgctt ctgctcctga acccaaattc catacaaata
    15661 atggtcatca gctacaagtg atagaatacc aattggtgag gagtagagta tttttacata
    15721 cttcttttgc attatttctt taatttttga taggccaagc gttcgccatc tactggcacc
    15781 ttaccaactt gtttaaaacc aagtttttca aaaatatgtt gcataacctt gttttcagca
    15841 tgcgtatctg agcgaaaatc aagataatca aaaccttcaa tcaagccctc taagaaggtt
    15901 tgagcaactc cttttccctg cacatctgct gccacagcaa tacggtgaaa gactagatac
    15961 tctgactctc cagcttgcca gtttccctca taaatagctt cataggcctc ctctggactc
    16021 ttggtcacag cagcataggc tagcagttct ccctcttcca aggctacgta ggcttgccct
    16081 gagatgatat catcgataat aacatctgca tttggatagc cattttgcca ctggtcacta
    16141 ccagcatctg ctaaacattt tttggcatcc tccatcacct gcatgatggc atctacttca
    16201 tttggaaaag ctaaacgaat ttccatcttt tttcctcatt tctgactagt ttctcccatc
    16261 atagcataat ttaagtattt ctacaagcag ttaaaacttg actttgtgtt tttgttattt
    16321 tataatctag ttatcaaaac tatataaaaa ggagttaaaa atgaaaacta ccttttccta
    16381 cccaaaatgg gcagaaattc caaacattga cctctatctg gaccaggttt tgctctatgt
    16441 caatcaggtc tgcgccccta tctctcctaa taaagacaag ggcctaacag catctatggt
    16501 caacaattat gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat accaacgcca
    16561 acagattgcc cgtttgattg ctatcacaac cctcaagtct gtattttcta ttcaagaaat
    16621 agcccagaca cttaatactc tacaaactca agcaagttca gaccaactct acgatgcttt
    16681 tgtggactac atgaaccaag gaattgaccc agctaaccct attatccaaa ccagctgcca
    16741 aaccgttaaa ctctatcatc aaactctaga cttaatcgat catactcaag aggaggtaat
    16801 ccaatgaaca ctagtcttaa actcagcaaa caactcagtt ttggagagga gattgctaat
    16861 agcgtgaccc atgctgtggg tgcagtcatc atgcttatct tgctgcctat ttcatccatc
    16921 tatagttatg aagcacacgg atttttatcc tctatcggcg tttccatttt cgtcatcagt
    16981 ctctttctca tgttcctatc atccaccatt tatcactcta tggcctatgg ttcgacccac
    17041 aaatatgttt tgcgaatcat tgaccattct atgatttacg ttgccattgc cggatcatac
    17101 acgcccgttg tcttgacctt gatgaataac tggtttggct atctgattat tgtcatccaa
    17161 tggggaacga ccatctttgg tattctctat aaaatctttg ctaaaaaggt caatgagaaa
    17221 tttagccttg ctctttacct gattatgggc tggttggttc tggctatcat tcctgccatt
    17281 atcagtcaaa cgacacccgt tttctggagt ctcatggtaa ctggcggact ctgttataca
    17341 gttggagctg gattttatgc caagaaaaaa ccttatttcc acatgatttg gcatctcttt
    17401 atcctagctg cgtccgcact tcaatacatc gctattgttt attacatgta aaaaagttga
    17461 gaaattcaat ctcaactttt ttctttacac atattgataa agtactggtg caagcgcaca
    17521 tcatcagtca attctggatg aaaagaactt accaacatat ttttttcttg ggctgcaaca
    17581 atttgattgt tcactgttgc taaaatttct acaccctcac caacactact gataatcgga
    17641 ccacggataa aggtcattgg aatcttgcca actcccttac attctgcttc cgtgtagaaa
    17701 cttcctaatt ggcgcccata agcattacgc tcgaccacca tatccatagt tcctagatga
    17761 ctctctttct gagaagtgat ttccttagcc agcaaaatta agcccgcaca ggtcccaaac
    17821 actggtaagc cagatagaat ggcttctcgg atgggaagta gcatgttctg gtcacgtaag
    17881 agcttgccca tggttgtaga ctcaccacca ggcaaaatca aacccgacaa gtcactctga
    17941 tcttgctgaa aatcatctag atttctgagt tctacactct cgacacctaa ttgatctagc
    18001 acttttgcat gttctgcaaa ggccccttgc aaggccaata ttccgatttt catctatttt
    18061 cctcgttcag ccatgagaat ttggatttca ttttcattaa taccaaccat ggcttctcct
    18121 aaatcttcag agatttgagc taggatttga ggattacgga agttagtcac agccttaaca
    18181 atggcactcg ctcgtttaac aggatctcct gacttgaaaa tacctgaacc gacaaagacc
    18241 ccctctgccc ctaattgcat cattaacgca gcatctgctg gcgttgcaac acctccagca
    18301 gcgaaattta caactggcaa ttttccatgt tcatgaacat attggaccaa ttctacaggg
    18361 acttgcaaat ccttggcagc aacataaagc tcgtcctcac gtaagttttg aatgcggcga
    18421 atttcctgat tcatcatacg catatgacga acagcttgga cgatatcccc tgtccctggt
    18481 tctcctttgg tacgaatcat ggaagcacct tcagcgatac gacgcaaggc ttcacccaaa
    18541 tccttagcac cacagacaaa aggaacttgg aattctttct tgtccacatg gaaacggtca
    18601 tcagctggag atagaacttc actctcgtcg atataatcaa tttcaatagc ctctaaaatc
    18661 tgagcttcaa caaaatgccc gattctgacc ttagccatta ctggaatact aaccgcttct
    18721 tggatttcct taatcatctt tgggtcgctc atgcgggaaa ctcctccagc tgcacgaata
    18781 tcagccggaa ttcgttccaa ggccatcaca gctgccgcac cagcagcttc tgcgatacga
    18841 gcctgttcag gattctgcac atccataata acaccaccct tgagcatctg tgccaagttt
    18901 ttatttagtt cataacgatt ttcagtcatt tgttttatcc tcatcatttg tattggtagc
    18961 taccttttca ttttaagtca gaacagaatg aagcacaaga taaaaaaact ataattgtat
    19021 ggggacaaat tagctaaaaa ctatctgacc ttaacttaag gccagatagc tcattcattt
    19081 ttatttttca gccgtaaggg cagccattgt gatgtagttg tatggtttgt tgaagtgtgg
    19141 caagaagaag aggtctgtca atgccaattt atcaattgtc acatgctctt ggatagcaag
    19201 tgagaacatg tggattccca tgctaattgc aatatcatgt gaaaccattt gggcaccaag
    19261 aatttcacgg ctatctttgt caaagacaat cttaattgct acttcatggt tgtcatgttt
    19321 catgaattct ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt aaccagcagc
    19381 tttcgctttt tcaagagtca aaccagttga aaccatgtga agaccgtaga ttgagatacc
    19441 atttgaacct tgaacaccga ttccttccaa ttcatgtcca caagcattgt aggcaccaac
    19501 gataccagtg cgaacagcat ttgaagcaag agcgatatag cttgtatctt tacgagcatt
    19561 gtcataaaca gtcgcacagt caccaacagc gtaaacgtct gggatagatg tttcttgttt
    19621 cttgtctaca aggaaggcac cgttgcggaa gagttcgatc ttaccacctg caagggctgt
    19681 gtttggacgg aaaccaactg caaggataac catatccacg tcaaagcttt ctttgtcagt
    19741 aatcaagcgt tcaactttac cgtcaccttc gattgcttta acagtttgac ctagagccaa
    19801 gcggatgttg tgatcttcca agttcttcgc catcatttgt gtgaagtctt tgtcatagta
    19861 accgttcaag acagtatcaa cgatatcaac aaggacaact tcttttccaa gacgttcaaa
    19921 ggcttcagca agttcaacac cgatgtaacc accaccaaca acggcgatac ggtcgaggtg
    19981 ttggctcttg tcagaaagtt tattgataac ttcttcagca ttttggtaca atttcacgaa
    20041 ttgtacgttt tcaagagttg ctttaaattc gcggtttcct ttaacaattt caacaccttc
    20101 gattggtggc aagattggtg tagaacctgt agcgaaaatc aatttttcgt atgattcttt
    20161 gtgctctttt ccttcaactt ccgctgtaac tactttgtta tcatagtcga ttgaaagaac
    20221 aggtgagttc atgtaaactt tagcaccttt agcttccaat ttttctttat cagaatagaa
    20281 caagccttca gcaccgtcaa tttgttcacc aatccaaaga gccattccac atcctaggaa
    20341 agagatgtta gagttttggt caaatacaac aatttcgttc tcatttccaa aattatccaa
    20401 catggtattg atacatgctg taccagcgtg gttagcaccg actacaacga ttttactcat
    20461 aaaaatttcc tgccttcatt ctaaatttac cttactagta taccatttac cgttagcgtt
    20521 tacaaggggg gtactattat ttcagcattt tttatcaaaa ataattcccc atttatcctg
    20581 ttttcaagcc tgatgaattt tatgagcata tttcttgact ttttccaaat tttgtttgtg
    20641 aaaattctaa ctttatggta ttataataac atgaaaatga aatgtaaggg cttcaattta
    20701 gatgattatt tgatattaca acttattttc tataagagaa aggagttggt agcttgactc
    20761 ttcgttcaca ttctgaacgg ctaatgggga ctactatcac tatttcatta gtggatgagc
    20821 aagccgatat ctttctccaa aaatcctttg acttgctcaa agaacttgaa taccgcttca
    20881 acgccaatag tcaagaatct gagttgatgg aaatcaatta tcaagcagga atagcccccg
    20941 tcacggttca tccagacctg tttgagctga tttcacttgg gttagagcat agcctagcgc
    21001 tctctagcca cctcaatatc agcattggtc ccttaattca aacctggcgt atcggttttt
    21061 cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta atcaatcctc
    21121 atggtatcga gttagattct tctacttcta ctgtgttttt aaaacagaaa ggaatgaaga
    21181 tcgatctagg ttgtttagcc aaaggataca gtgcggataa ggttgcccaa tttcttagga
    21241 aagagggggt gacttctgcc ttgatcaatc tgggagggaa tatcctgacc attggaaaaa
    21301 atcaggcaag aggggataac ccatggcaaa tcgggattca agacccagcc aatcctaggg
    21361 gaaatcattt aatgaccatc cctgttgtca ataaatctgt cgtgacttca ggcatttatg
    21421 aacgtcacct gaccgtcgat ggacaagatt accatcacat ttttgacagt caaacaggat
    21481 atcctgttga aacggaacta gcgagtctaa caatcatctc tgataaatca gtcgatggcg
    21541 aaatctggac gactcgactc tttggagaaa gacctgcttc tatcctctgg caagtcgaaa
    21601 gtttggaggg catcgaagtc atcctcatcg ataaagaagg ccacctaagc tgttcttcag
    21661 gaattcctac tctatagaga caactgtttc aatggaattt taaaattgta ttatgtaaaa
    21721 agagaaagga aatctcatgt taaaacttat tgctattgtt ggaacaaatt caaaacgttc
    21781 tacaaaccgt caattgcttc aatacatgca aaaacacttt actgacaaag ctgaaattga
    21841 acttgttgaa atcaaggcca ttcctgtctt caacaaacca gctgacaagc aagtacctgc
    21901 tgaaatattg gaaattgctg ctaaaatcga agaggcagat ggcgttatta tcggtactcc
    21961 tgagtatgat cactctattc cagctgtttt gatgagcgct cttgcttggt tgtcttatgg
    22021 tatttaccca cttttgaaca aaccaatcat gattacaggt gcttcttacg gtacgcttgg
    22081 ttcatctcgt gcccaattgc aacttcgtca aatcttgaat gctcctgaaa tcaaggcaaa
    22141 tgttcttcca gatgaattct tgctctcaca ctctcttcaa gcatttaacc caagtggcga
    22201 cttggttgac cttgatgtta tcaagaaatt ggatgccatc tttgatgact tccgtatctt
    22261 tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta cttcgcaaag atgctgaaga
    22321 ctttgactgg gaaaatttgt aagataggag accaaaaaga atgaaatttg ttggacttgt
    22381 tggatcaaac tacgatcaat catataaccg taagctcttg gaatttatcc gtcgctactt
    22441 caaactcaaa tttgaattag aagttcttga aattgacgaa gttccaatgt ttaaccaaga
    22501 tgaaaaatgg gatgaaagtt tccaattacg ttatttatat aacaaaatta ctcgtgcaga
    22561 tggtgttatc attgctactc ctgagcataa ccacactatc tcagcttcac tcaaatctgt
    22621 acttgaatgg ctttcatacg aagttcatcc atttgaaaac aagcctgtta tgattgtggg
    22681 tgcatcatac tatgaccaag gaacatcacg tgctcaagtt caccttcgta aaatccttga
    22741 tgctccaggt gttaatgcct acacgcttcc aggtaacgaa ttccttcttg gtaaagctaa
    22801 ggaagctttt gataacaacg gaaatatcac caacgaaggc actgttaaat tccttgaaac
    22861 ttgcttagat aactttgtta aatacgtagg agtcgtttcg aaattgaaaa aaccaaaacc
    22921 aatcgaatca gaagacttgg attgtggaaa accaatcgct acaaccatca cagaagttga
    22981 ccctgacgat ccagaatggg tagaaaaagt tgcagcattc actggtgctg tttctggtga
    23041 tacctatgtc aaattggacc acggtatcct aacagttaac caaattgata tgttcttgaa
    23101 agctatgcca tttgaattga catacgctga cgacaacaac caattcctct actacaacaa
    23161 cgctcaccaa gatccagaca ctatgttcgc taaacgtgta ccacctcaat caggtagccg
    23221 tatgtcgact gttcatggtt ctcttccacc agcacgtatg aagaacgtag agtgggttat
    23281 cggaacactt cgcaacggaa accaagaata cgtccgtacg atcgttccag gttctcctgc
    23341 aggtgttatc aacactcaca actaccaagc aatgtactat cctgatggat catacgctgg
    23401 tatcaatgaa atcgtcttta acttccaacc atggcttgac tggtacctaa aagagactgg
    23461 tcaacgtttg gtgggtggta gcggaccatt tgctcctgct gccggaggtc atggagacgc
    23521 cgatgctact tctagcgctt ctgattcagg ggatgctgga ggccacggtg gtgacgcaga
    23581 cgctacagcc ggtgcaagtt actaatgata gtttttagga actattatgg ttcctttttt
    23641 agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt gttatcgttt catctatctt
    23701 tgttaaaaga aagaatacat atactcaatg aaaatcaaag agcaaactag gaagctagcc
    23761 gcaggctgta cttaagtacg gcaaggtgaa gctgacgtgg tttgaatttg attttcgaag
    23821 agtattatta tgaatttgga tcatcaagac tacggccatg taatcctttt tcacgttgta
    23881 cttggcgtag tttttctggt gtaacatcgt ttccttcttc gtccacaatt ttgattcctt
    23941 caatgtggtg acgaacagcg cggcgataac cttcgatgta ctcctcacgt agtttggctt
    24001 gttccacttt ttcttctggt gttaagcctt ctgttttttt ctttttagca agctcattga
    24061 tacgagcaat ttttttcgga tccatttctt ctcctttgta ataagataaa gtccgtttat
    24121 caaattttat ttagtgttaa tttggttaaa acaagcaaac ttagctgctt tcttggttag
    24181 ttgtgacaag attgccaaac gattttgacg gacagcctga tcttcagcca ttaccatagt
    24241 attttcaaag aaagcatcaa tgactgggct aagcgcaaaa agttgtttca attgctgact
    24301 tgcaggtcct gataaaatga gtgtttctac tgcttctgcc aaagcttttt cttggtcatt
    24361 ctcaaatagt gctgaatcaa ccgtagcaac cccttctgcc ttctcggcca ggttaaaggc
    24421 acgagaaagt gattcaacag atggtttaaa atcttcttcc ttgcttactt ctacgagagc
    24481 acttgctgct tccaacatat ctgccacaac aaagtttgaa cctgcaagaa ctgcttcctt
    24541 gatatctttt ggagtagagc ccatcatctt atcaacacga gccttgataa agtccataac
    24601 ctctgcttta ttttcataag tcaaactgtc aaatttcaat gcataaaggc tatcaatcag
    24661 ctcatccata gcaatgtgcc aaccaaaggc atccaagata cgaaccacac cttgagttgc
    24721 acgacgaagg gcataagggt cattagaacc tgatggaatc aatcctactg agaagaaact
    24781 caaaatcgta tccaatttgt ctgcaatggc tagaactgcg ccgaccttgc tctctggaag
    24841 ttctccttca gctgatgtag gcatgtagtg ttcacgaata gcagctgcca ccgctggagt
    24901 ttcaccagca agaagggtgt atttttcacc cataattcct tggagttcgt caaattcacc
    24961 aaccatacct gtcaacaagt caaacttgta aatggctgct gcacgagcaa ggtcaactgt
    25021 ttcatccact gacaaactag ctttttctgc caaaagtaca gtgatttgac ccgtacgaat
    25081 catgtgttca cgaagggaac caatcttctc atggaaggtg acattgttta atttttcaac
    25141 aagatctgaa atcaccaatt tttggtcttc acgccagaag aattctccgt cttccaagcg
    25201 ggctaccaag actttttcat ttcctttgat gacatttttc aaacgctctg cgtttccgtt
    25261 acgaacagaa atgaagtttg gcaagagttt tccatcttga tcacgaacaa caaagtaacg
    25321 ctggtgttcc ttcatagaag tcaccaagac ttcttctgga acttcaaggt atttagcatc
    25381 aaaacttccc atgaaggcag ttgggtattc aaccaaattc aagacttcat tcagcaaatc
    25441 cgcatcaatt tcgatacgta caccatgttt tgcctcaatt tccttgattt ggtcaacaat
    25501 catttgctca cgttcacatg gatctgcgat tacaaactgc ttacgaaggt cttcttcata
    25561 gctcaatgct gactgaatct tggtttcttg tcccaaaaaa cgatggccac gactcacacg
    25621 acttcccttg atatcaagga aatccaagtc aaactcttgc tcatccaaga gaacagttaa
    25681 agtgtgaaca gggcggatgt attcaaagct atttcccgcc cagtgcatgc tgacagggaa
    25741 agtcagtgac ttcaagacat ccacaatgcc tggaacaatg gcttcaactg cttgaccaat
    25801 ttcttcctta gtgacataga catattcttc acccttgatt tcacggaatt cgatatcttc
    25861 aacagtcaaa cctttcccac ggacaaatcc ttgagctgct ttggtgaagt ttccatcact
    25921 atctaaggca attttctttg ctggaccctt gaaatcttct gttaaatcag actgtttgtc
    25981 tgcaagacca gttacacgaa cagccaaacg acgtggtgtt gagaaagttt gaatggcttc
    26041 aaaagacagg cgttttccct tgaggaaggc tgccattttt tcgcctagtt gtttttcact
    26101 tggcgtaaca acataggctg gtaattcttc aagaccgagt tctactaata agttttttgt
    26161 catgtttttt cctttacatt ttcttcaatc ttttttgata tgcaccttag gtactgggga
    26221 cgtcgctaac taactctgtg agtctgtatg gaaatccaat gctaaattta tcaagatttc
    26281 caacaatctc atcaaagtgg atttagctga ctgatttttg aacctaaggt ttcaaaaatc
    26341 cccacataac agtacagcgg tgcatatccc tctagcaagt cttcgacttg cctctaacga
    26401 ttttagagta cagtattact cactattctg cgtcttctgc taaaagttta actcgtgttt
    26461 cttcatccaa aagtgggtaa cctaggcgtt tgcgttctgc aacaaaggtt ttggctacaa
    26521 cacgggccaa gttacggata cgagcgatat agcctgcacg ctctgttaca gatacggcac
    26581 cacgcgcgtc aagcagatta aaggtatgtg aacatttgag aacatagtca taggcagggt
    26641 gtaccaagcc ttcttctaat gcacgaccag cttctttttc aaacttatca aaattttcaa
    26701 gcaacatttc ttggtccgaa atttcaaatg aatattttga gtgctcatac tcaggctgga
    26761 taaagatttc tccgtatttt acaccatcag cccactcgat atcatagaca gagtctactt
    26821 cttgaatgta agaagccaag cgctccaaac cataggtaac ttccgcagtc acagggctag
    26881 ttgccaatcc accgacttgt tggaaataag tgaactgagt gatttccatt ccgtcaagcc
    26941 aaacttccca accaagacca gctgaaccag ttgatgggtt ttcccagttg tcctcaacaa
    27001 aacgaatatc gtgctccaaa ggattgattc ccaatttttc caaagactca aggtaaagtt
    27061 cttggatatt tgatggagaa ggcttcatga ccacctggaa ttggtggtgt tggtagagac
    27121 ggttagggtt ttccccataa cgaccgtcag caggacgacg tgatggctct acataagctg
    27181 cattccatgg ctcaggtccg atagcacgaa ggaaagtgta aggactcatt gttcccgcac
    27241 ctttttcatt atcataagcc tgcataagca tacaaccttg gtcattccaa aattgttgca
    27301 aagtaaggat gatttcctgg aaagtcaatt tcttagacat tgtttactcc tttagttttt
    27361 atatttcttt ttcaattaat ttctgctgaa caaaccaatc taacaaggga aaagtttttt
    27421 ctgtatttgc ccataaatga taagaatcta agaccgcttg tacactacct aaattttcta
    27481 ccaacttatc tactgtcaaa aagctgcgcc agtattcata aaaaatactt gcatagttct
    27541 tatcataagt cgaagaacca aaatcattca atgaatgcca accatacttc ttctgaaaaa
    27601 gttctacgag agattgatta caaatttttt ccgcttgaaa ttcctcttct gtcaagaaat
    27661 acttgcgact aatatattca accatcccct cttcgaacca gatataagag tcataaccat
    27721 caaaatcatc taaaaaatgc tccgaccaat gagctaactc atgtcctaca atctgtaaga
    27781 ggaaattttc agataaagaa tgatagtgac tttctattgc ttgagtttgc tcagaacact
    27841 cgtagtccat caattgatac aaatacaact ctttccaaac agctaaatca ggcgccataa
    27901 ccattcgtct attatttgta taggctggaa cagcgctttc cctaataatc tgtgtagcag
    27961 cattaaaatc tgaccaaata acggcttgcg gtaaatcaca gactgcaagt tcattcttta
    28021 aaaaagattg ataatctttc aacttttcag tatttcttac tacaaaatca cgaaatgtag
    28081 ctagttgact atcgtctttt acaagataaa ggttgtccac ggctctcctt tctttcacac
    28141 aatagactga ataagcaaaa gaaccacatc tgacaatcct aggttgattt aacctagggg
    28201 cgtcagaaac gcggttccac cctaatttat tacttcattg tttttgaaaa tactacagaa
    28261 agcgccagct cattattttg ccctacttgg ctcccactgt cccaagctcg cttgaagaac
    28321 gccataagac tttctttcct gctgactatt atatcaaaaa ttagaataat gtacaattct
    28381 ttttatgatt ttctagaaat ccacatcatc aactcgtgga gcccccgact gaacagcagt
    28441 cgtttttaag gtttctctct cctcatgact cagttcaatt ccaaaacaat caagattagc
    28501 ttgaatacga gaggttgtga cagattttgg aagtggtaaa aatccttctg ccaagctcca
    28561 ggccaaggct atctgagcaa ccgattttcc gtgatttgct gcgatttctt ggacttgctt
    28621 gctatcaaac agttctcctt gtccaaaagg cccccaagct tccaataaaa ttcccttttc
    28681 acgacagtaa gctacgactt cctcttgata cacacctggc gccaagcgaa cttgattgac
    28741 cgcaggaacg atagttgcag tttcaagcaa ggcatccaaa tgatggggaa gaaaattgct
    28801 aacgccgata gcacggattt tcccttcttg atagaggtct tccatcgctc tccaaacttc
    28861 cgcattgcga gttttccatg cgtcattttc tctgagcggt tttgggttcg gccaatgaat
    28921 caaatacaaa tccaaataat ccaagcccag tttttctata gatttttcca aagcttgacg
    28981 agtttgctca taggtttgct gactattcca aagcttggta gttacgaaca tttcttcacg
    29041 tggaactccg ctatctttga ttgcttgacc aacactttct tcattctgat aaatcgccgc
    29101 cgtatcaata tgacgataac cagccttcaa ggattctaac actgcacgat aggcttcttc
    29161 tccatcctta gccttaaaag ttccaaatcc caatactgga atttctactc cattatttaa
    29221 ttgataggta ttcatatgct tctccttcta tatttattca tcaattatag cataaaacat
    29281 tttttaagta gtactatctt ctgtaaaaaa taagtctgtc aaatatctaa cagacctatt
    29341 ttttcttgct tattcatcac gactatagta cagctcatga gcttttaggc gagtattgag
    29401 catctctggt atggtcacaa aggtataacc ttgatttttc aaatactcaa tgacccttgg
    29461 caaggcattg actgtcggac tgtgaatatc atgcatcaaa acgatagagc cgttagctac
    29521 ttgatgctga atttctgtca aaatagatgc ttcattttta ctcttccagt ccagactatc
    29581 cacatcccac atgataaagc tcaaatccaa gctattgcga atatcatctg taatagcacc
    29641 ataaggtgga cgcatgagtt tagaactaga acccagcact ttagttagca catcctcagt
    29701 atcagtaatc tgctttttag cttcatcaag agagagttgc gagagaatcg gatggctcca
    29761 actatggttt ccaacaacat gaccttcaga ttttatcctc ttcaccaagt cctcattccc
    29821 agaaacattt ttcccaagca caaagaaagt cgctttaata tcatatttag ctagggtctc
    29881 taatacctgc ggggtcgttg ctggatttgg accatcatca aaggttagag cgacaacttt
    29941 ttgatatttc ttatcaaagt aagattggta caaggccgca tctttttcga gtaagtacga
    30001 agattggata acatcaaaga aagcagatac tggcaaggct atctcttcta aattttcaac
    30061 cacaggactt ggataaagga taatctgact atccttgtaa tcaaaattcc atgcagacaa
    30121 gtcttggtca gagaagtttt ttacaatctg ctcactctgg tcttgctcta tttttttatc
    30181 ctctatgaag gaggtcaact cttttatcag ctgttcctta gccttactag catctgaaaa
    30241 cagttggtca agtgtaaaag gttgcccatc ttctgttaag tgaacctttc ctagactggt
    30301 cttttcagtc tcttcaacct taaaagcaac taaatcatag atttgtttgg tcacattacg
    30361 attaacgact ccctttaaac ctgactcttc ttgctctgta tagtagaaaa caagattgtc
    30421 cttactttct agcttgtcct taacatcttg atttatcaac tccctaacag aggaaatcac
    30481 tttctcccct tggagaggat aataggcaat cacttcggct tgcccctgac gaaaatgctc
    30541 cttctgattt ccctcactca attgatcatc tttctctttt ttgagcgatt caatcttttg
    30601 ctcaaaactt ttttgctggt agatcttaaa agcaataaat ccgcctaata ggcaaataga
    30661 aattgctaaa ataccaatca aagccaataa tacatgtctc gttttcccgt gtctgccacg
    30721 tcctagtcta cttttattca tatttatatc ataacaaatt tgagcaataa tttcaatgat
    30781 acaatttggc aatccacaat tcctctagca agccaaagca tcttacatca actccaacat
    30841 ccgtatctgt agagattatg tagttttcta tctatggaat ttctagtaga ttgaagctag
    30901 aatagtagac ctatacttct aaaacattgt tagaaatcga tttgattgtc ctgatcgatt
    30961 tgtcctgttc tcatttcatt ttactataaa actatgaaaa gctaggtcat ctgagaagta
    31021 attactatcg acaattgcga tagcgtatac tggtgcgatt tgtttgtagc tctggtgggt
    31081 atcaccttca cgttggcgaa ttttttctag gttttgatta acctgactgc acagataagc
    31141 ccataggcga ttgatgaaaa aattctgatg atgaacctga atttcgatga taacttggat
    31201 tccattatct aactccgcca agacgtctat actagtatag aaatcctgcg ctgagtaggg
    31261 catggaaggc aagacgtgaa tgttacttcc ctccaaaatc gtcacatttt ttgctggcaa
    31321 gtccagcata tcgcggataa attgacaaat cattagttgg gctgataccc ggatgtctga
    31381 gaatcctcct tttcctcctt ctattatagc acatttttaa atctaggttt gctagattct
    31441 atgcttctat ctatttattc ggaaaagaaa gctaatagct tatttgaaat tttctcctct
    31501 ctgttggata gtcccgtcta tctatgttat aatgaaagaa ggatttaaaa tcggaaaagg
    31561 agtatttatg ctaaaattag gtgtcatcgg aactggcgct atcagccatc atttcataga
    31621 agcagcccat accagtggag aataccaact ggtcgcaatc tattctagaa aactagaaac
    31681 tgcagcaacc tttgcttctc gctatcagaa tatccaacta ttcgatcaat tagaagtctt
    31741 cttcaaatct tcttttgatt tagtctatat cgccagtcca aactccttac attttgctca
    31801 ggcaaaagct gccttgtctg ctggtaaaca tgttattctc gaaaagccag ctgtcactca
    31861 accacaagaa tggtttgatt tgattcaaac agctgaaaaa aataactgtt ttatctttga
    31921 agcagctcgt aattaccacg agaaagcctt tactactatc aaaaactttt tagcagataa
    31981 gcaagtgtta ggagcagatt tcaactatgc caaatactct tccaagatgc ctgacttgtt
    32041 gactggacaa acaccaaatg tcttttcaaa ccgttttgct ggtggagccc tcatggattt
    32101 ggggatttat cccctctatg ctgctgttcg tctttttgga aaagccaatg acgcgactta
    32161 ccatgctcaa cagcttgaca atagcattga cctaaatgga gatggtatcc tcttctaccc
    32221 agactatcaa gttcacatca aggctggaaa aaacatcact tccaatcttc cttgcgagat
    32281 ttatacaaca gatggaacct tgactctcaa cacgattgag catattcgct cagctatttt
    32341 taccgaccac caaggaaatc aagtccagct tcctatccaa caggctcctc atacgatgac
    32401 tgaggaagtc gctgcatttg cacacatgat ccagcaacca gatctgaatc tctaccaaac
    32461 ttggctgtat gatgcaggct ctgttcatga gctactatat accatgcgcc agactgctgg
    32521 cattagattt gaggcagaaa aatgaaaacc aaactaccga ctgaatggca agaactgagt
    32581 gaccaactcg gtttccaaga attcaccccc attcaaactc aactatttga gccccttctt
    32641 gctggagaaa acctcctagg agtgagccaa accggaactg gtaagaccct agcgtatctc
    32701 ctaccaagtc ttctcagact acaaaagaaa aaagcccaac aactcttgat tctagcacca
    32761 aacacggaac ttgctggaca gatttttgat gtatgtaaaa cgtgggcaga agctatcgga
    32821 ttgactgctc aactcttcct ttcaggttca agtcagaaac gacaaattga acgccttaaa
    32881 aaggggccag aaattctgat tggaactcct ggccgtatct ttgaactcat taaacttaaa
    32941 aaaatcaaga tgatgaatgt ggaaaccatc atcctggatg aatttgacca attactagat
    33001 gattctcaga ttcactttgt agaaaaaatc actcactacg cacctcgtga ccaccaactg
    33061 gtctacatga gtgccacgac caagtttgac caagaaaaga ttgtgccgaa tacacgcact
    33121 attaatctct ctgaccaaaa attggacaat atccagcatt tctacatgca ggtagaccaa
    33181 cgtcatcgag tggatatgct acgaaaactg gctcatgtag aggatttccg tggtctagtc
    33241 ttcttcaata gcctgtcaga ccttgggaat gccgaggaaa aactacagta tcgtgatata
    33301 ttgactgttt ccctcgctag tgatgttaat gttaaattta gaaaaatcat cttagaaaag
    33361 tttaaagata accaactaac cctgcttctt gcaactgacc ttttggctcg tggaattgat
    33421 atcgatagcc tagaatgtgt cgtaaacttt gatattccta gagatagcga aacctacaca
    33481 caccgtgctg gccgtactgg ccgtatgggc aaggaaggat atgttattac tctcgtcact
    33541 catccagaag aaatcaaaaa acttaaaaag tttgcaagta tccgagaaat tgtcctaaaa
    33601 aaccaagaac tctatatcaa ataaagcccc attgctctat acacatccag tgtatggagc
    33661 ttttttataa gcaattcaat tttatactca tctgctttca aaaagcattc tattccatct
    33721 ccgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat cttggagttg
    33781 attcatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    33841 tttccacact tgttcaatgg gttcatctct ggtgtgtatg gaggaataaa ggtaaaatca
    33901 atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt
    33961 aaaaaataat catctggata agcttgtgaa agctcttcta aaaagacgtt catccactca
    34021 gtattacatc caccagctat taagaaaaat gattcgcctg tatggggcat caacagctcc
    34081 ataacaatag cgaaattctc gtatatagtg actatggaca tgtggaccta ctcctattgg
    34141 agaccaacaa gatcccagtt tactgattct accgaaacca gcctcatctt ggtacatcaa
    34201 gcgaacctta tgaaaaggtc tactggtttt aaagcgcttt cttgtcttct tgaattgaga
    34261 ttttattttt agacgcgaca atggtttgag cgtctgcttt cctaggatgt tctggacgtg
    34321 gcataatatt tcgccaacca tggtgcttca acagttgata gaaggcatca cgtgtgtagg
    34381 aacgatataa gcctgaaata aggtattgta acaaattctc ctgcctctgt agccttcaaa
    34441 tggcgggcaa gaaaggcttt ctcttcctca actgtcatat atgcatggtt acgaccacca
    34501 cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa
    34561 atcgttgttt gattacagtc taaaagatct ataatctctt tataagattt gcccatcaga
    34621 cgaaatagaa cgatttgaag gcgtttatga tatttagctg tacgaaagtc ttttaaaagt
    34681 gttttgatgg tttggatttc ttctttagtt gatttcatat tactattgta taatgctttt
    34741 tgatttgagt ctagtattat actcttcgaa aatctcttca aaccgcgtca gcttcgcctt
    34801 gtcgtataga atgttactga cttcgtcagt tctatctaca acctaaaaac agtgttttga
    34861 gcagtctgca gctaactttc tataacaaaa tgaaataaga acaagacaaa tcaatcaaga
    34921 caatcaaatc gatttctaac aatgttttag aagtagatgt gtactattcc agtttcaata
    34981 tattatagtt tgctctttga ttttcattga gtattagttc aatatctaaa aaaagag
//
LOCUS       DAVLAQ010000019        34694 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000019 DAVLAQ010000000
VERSION     DAVLAQ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.019"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            226..1077
                     /locus_tag="VXB71_000920"
     CDS             226..1077
                     /locus_tag="VXB71_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0451054.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(1309..1659)
                     /locus_tag="VXB71_000921"
     CDS             complement(1309..1659)
                     /locus_tag="VXB71_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451055.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(1799..2134)
                     /locus_tag="VXB71_000922"
     CDS             complement(1799..2134)
                     /locus_tag="VXB71_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451056.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(2222..3532)
                     /gene="der"
                     /locus_tag="VXB71_000923"
     CDS             complement(2222..3532)
                     /gene="der"
                     /locus_tag="VXB71_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0451057.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(3546..4259)
                     /locus_tag="VXB71_000924"
     CDS             complement(3546..4259)
                     /locus_tag="VXB71_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0451058.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(4256..5152)
                     /gene="dnaI"
                     /locus_tag="VXB71_000925"
     CDS             complement(4256..5152)
                     /gene="dnaI"
                     /locus_tag="VXB71_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0451059.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(5153..6322)
                     /locus_tag="VXB71_000926"
     CDS             complement(5153..6322)
                     /locus_tag="VXB71_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0451060.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(6323..6796)
                     /gene="nrdR"
                     /locus_tag="VXB71_000927"
     CDS             complement(6323..6796)
                     /gene="nrdR"
                     /locus_tag="VXB71_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0451061.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            6936..7301
                     /locus_tag="VXB71_000928"
     CDS             6936..7301
                     /locus_tag="VXB71_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0451062.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            7306..8001
                     /locus_tag="VXB71_000929"
     CDS             7306..8001
                     /locus_tag="VXB71_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451063.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            8018..8785
                     /locus_tag="VXB71_000930"
     CDS             8018..8785
                     /locus_tag="VXB71_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451064.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(9138..10337)
                     /locus_tag="VXB71_000931"
     CDS             complement(9138..10337)
                     /locus_tag="VXB71_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451065.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(10334..11227)
                     /locus_tag="VXB71_000932"
     CDS             complement(10334..11227)
                     /locus_tag="VXB71_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451066.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11344..11424
                     /locus_tag="VXB71_000933"
                     /pseudo
     CDS             11344..11424
                     /locus_tag="VXB71_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11934..12122
                     /locus_tag="VXB71_000934"
                     /pseudo
     CDS             11934..12122
                     /locus_tag="VXB71_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            12537..13154
                     /locus_tag="VXB71_000935"
     CDS             12537..13154
                     /locus_tag="VXB71_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0451067.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(13474..14361)
                     /locus_tag="VXB71_000936"
     CDS             complement(13474..14361)
                     /locus_tag="VXB71_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0451068.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(14510..16393)
                     /locus_tag="VXB71_000937"
     CDS             complement(14510..16393)
                     /locus_tag="VXB71_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0451069.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            16770..18224
                     /locus_tag="VXB71_000938"
     CDS             16770..18224
                     /locus_tag="VXB71_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0451070.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            18205..19170
                     /locus_tag="VXB71_000939"
     CDS             18205..19170
                     /locus_tag="VXB71_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0451071.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(19205..20479)
                     /locus_tag="VXB71_000940"
     CDS             complement(19205..20479)
                     /locus_tag="VXB71_000940"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0451072.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(20479..21651)
                     /locus_tag="VXB71_000941"
     CDS             complement(20479..21651)
                     /locus_tag="VXB71_000941"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0451073.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(21782..22030)
                     /locus_tag="VXB71_000942"
     CDS             complement(21782..22030)
                     /locus_tag="VXB71_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451074.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(22098..22723)
                     /locus_tag="VXB71_000943"
                     /pseudo
     CDS             complement(22098..22723)
                     /locus_tag="VXB71_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(22785..23234)
                     /locus_tag="VXB71_000944"
     CDS             complement(22785..23234)
                     /locus_tag="VXB71_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0451075.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(23236..23994)
                     /locus_tag="VXB71_000945"
     CDS             complement(23236..23994)
                     /locus_tag="VXB71_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0451076.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(24109..26088)
                     /gene="pknB"
                     /locus_tag="VXB71_000946"
     CDS             complement(24109..26088)
                     /gene="pknB"
                     /locus_tag="VXB71_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0451077.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(26085..26825)
                     /locus_tag="VXB71_000947"
     CDS             complement(26085..26825)
                     /locus_tag="VXB71_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0451078.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(26840..28153)
                     /gene="rsmB"
                     /locus_tag="VXB71_000948"
     CDS             complement(26840..28153)
                     /gene="rsmB"
                     /locus_tag="VXB71_000948"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0451079.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(28146..29081)
                     /locus_tag="VXB71_000949"
     CDS             complement(28146..29081)
                     /locus_tag="VXB71_000949"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0451080.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(29094..31490)
                     /locus_tag="VXB71_000950"
     CDS             complement(29094..31490)
                     /locus_tag="VXB71_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0451081.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHARDVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(31556..31870)
                     /locus_tag="VXB71_000951"
     CDS             complement(31556..31870)
                     /locus_tag="VXB71_000951"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0451082.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(31895..32521)
                     /gene="gmk"
                     /locus_tag="VXB71_000952"
     CDS             complement(31895..32521)
                     /gene="gmk"
                     /locus_tag="VXB71_000952"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0451083.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(32651..34264)
                     /locus_tag="VXB71_000953"
     CDS             complement(32651..34264)
                     /locus_tag="VXB71_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0451084.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(34334..34624)
                     /locus_tag="VXB71_000954"
     CDS             complement(34334..34624)
                     /locus_tag="VXB71_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0451085.1"
                     /translation="MEVEEKSIELSYEYVDDGYSGSNFERPNFKNMIDDLNKGKFSII
                     MVKDLSRFGRDYIESGKYLQKIFPEKGIRFISVNDNYDSDNADVSDIHLRFV"
BASE COUNT         9918 a         7828 c         6593 g        10355 t
ORIGIN      
        1 tttacttatt atatatagac tctaatttct ttatccccaa aaccatgttt caaaccagat
       61 aagttgaatc caactccaaa tcaaaaatcc agagtttttc ggtaaattct tcaaatattt
      121 tttaaagccc atgacttttt ccctcctttt tgatataata ataccacctt tttctacgtt
      181 ttttataaat gtagaaaata ttcacattta cctaggagga acaatatgag atgggattat
      241 ggacaaattt ttaaagaaat tcgaaagtca aaaggattga cccaacaaga tgtatgtgga
      301 caagtcatac atcgaacaac tctaacaaat attgaacacg gtaaagttat tcccagtttt
      361 gaaaacatgg tatttcttct tgaacaaatt gatatgagct tggcagaatt caagtatata
      421 tgcaacgaat accatcctag taaaaggcga gatattattg tagagagcca aaatccgtct
      481 acttttcaag atactagaaa aatggttgaa ctcactgaga aatgtcaaaa atatcttaag
      541 acacatcacg atgttcctat tcaaaatatc tatcgtcata caaaaattgt cacagagtta
      601 cgaactaaag gattcaaaaa caaccacgtc ttgaaagatt tgtatgaaga aatttgggac
      661 tatcttgaac ctatggatac atggtacatt agtgatttga aattgcttgg aaccattctc
      721 tttttctttc cttctgaaaa tcttcccctt cttattgata gaattatgaa aaccatcgag
      781 aaatataaat acttccgaga aacaaaagca tttttatcat cttttttagc caatctctcc
      841 actgtatatt ttcaacatca tttattcaaa gaatgtgaaa caatcaccct acaacttttg
      901 gtattagcag aagaattaaa aatatacgat attcttggat tctctcaagt acgcttggga
      961 atactacaac ataactccga tttgattgat aaaggaataa ctttattacg actaaccaaa
     1021 gaagaggcat tagttaaaat actcgaaaaa gaaattaatg atttttcaaa cctataattt
     1081 gtaataactc tcatcatttt attatagtag attgtaatag aatgtaatag aatgtgaacg
     1141 aatcaattag gggatctaaa gcattttata ccaatgtttt ataagttgta ttgtattatt
     1201 ccatattcaa tccactatac aagatgaata tttctctcaa gtttcataat caaaataaaa
     1261 atgactgtat ctatagctcc ataaacaaat catagataca gtcatttttt agttcctaca
     1321 ccttccttta tgcacacctt tagatttccc tagttcccgc ctcaagcgaa tcattttttt
     1381 gaaaaagaca taggctaacc aatcactagc aaaagcgata agtagtaata atagccaaat
     1441 accccataac ttgatatctg tcaaatttct caagacgata ttgaaaaaca gaactgaaaa
     1501 aactgtccaa gcaaggctaa aaagagcata gagggtgatg taaatccagt aaaaatagta
     1561 aaaaattggg aaaaatttac tttctctatt atccttgtca atccagctga aaaagtaaaa
     1621 acagggtaat aagattatca ttttaaacaa gtgttccatc acaagcctcc ttttttaaat
     1681 tgttttcttt agtttcgttc tattaaatgt tattaccaat ataaaccttg gaatagcgtg
     1741 taataaatga ttttagaggt accataagcc acctcctaca aatagaaacc gatataaatc
     1801 aatgccttcc acccttagac ttccctagtt cctgtctcaa gcgaaacatt tctttgaaac
     1861 aggaataagt taaccaattc ataccaatag ctagcagaat aaaaagaaac caaatgcccc
     1921 ataacttgat atctgtcaca tttctcaaga cggtattgaa aaacagaact gaaacaactg
     1981 tccaagcaag gctaaaaaga gaatagaagg ggatgtaaaa ccagtaaaaa taataaaaaa
     2041 ttggaaaaaa cttactattt ctgttggcct tttcaatcca gttatcaaaa taaaagtacg
     2101 gtgctaaaag taagaattta aacaaatgtt ccatcaccga catccccctt cttttgatag
     2161 cgttttctat tattttatta tatcaaaaaa atccggaact gtcattccag attctacttt
     2221 tttatttgcg ttttcttgcg atgagatgaa tcggtgttcc ctcaaaaaca aaggccttgc
     2281 ggatttgatt ttccaagaaa cgcaggtaag aaaagtgcat gagttcttct tcattgacaa
     2341 agatgacaaa ggttggtggt ttggttgcca cttgggtcgc atagaaaatc ttgagacgtt
     2401 ttcctttgtc tgtcggtgtt gggttgatgg caatggcatc catgatgaca tcgttcaaga
     2461 cagctgatgg aatacgtgta ttttgacttt cgctgatttg cttaatcatc tcaggaagtt
     2521 tgtggagacg ttgcttggtt aaagctgata caaagataat cggtgcgtaa ggcaggtatt
     2581 ggaactgctc acggatatct tcttcccagt ttttcatagt gtggttatct ttttcaagcg
     2641 tatcccactt gttgaccacg ataatcatcc ctttaccagc ttcatgagca aatccagcga
     2701 tacgcttgtc gtattcacga atcccctctt ccgcattgat gaccattaag accacatctg
     2761 aacggtcaat agcacgcatg gcacgcatga cagagtactt ctcagtattt tcataaacct
     2821 taccagactt acgcatacca gccgtatcaa tcatggtaaa ctcttgacca tctgtatctg
     2881 taaagtgggt atcaatagcg tcacgagttg ttccagcaac aggactggca atgacacggt
     2941 cttctcccaa gatagcatta atcaagcttg attttccaac gttaggacga ccaatcaagc
     3001 taaacttaat gacatctgga ttttcttctt catattcatt tggaaggttt tccacaatcg
     3061 catctagtac atcccctgta ccgataccat ggacagatga gataggcagt ggttcaccca
     3121 aaccgagagc atagaaatca tagatatcat ttctcatctc agggttgtcc accttgttga
     3181 ctgcgaggat aactggtttg tgggtcttat aaagcttacg agctacgtat tcgtctgcat
     3241 cagtaattcc ttccttacca gacacgacaa aaacgataac atctgcttct tccatggcaa
     3301 tttctgcctg gtgcttgatt tgttccatga aaggagcatc gacatcatca attcctcctg
     3361 tatcaatcat gctaaaagaa cgattgagcc actcacccgt tgcataaata cggtcacgtg
     3421 tcactccttc gacatcttct acaatggaga ttcgctcacc agcgatccga ttaaataggg
     3481 ttgatttccc aacattggga cgtcctacaa tggcaatagt tggtagggcc ataatttctc
     3541 actttctaca ataatttctt ctgttcaaga ttttttctag ttgagcttgg ttcagcttga
     3601 ccaaactgtt ctgctaggcg ctgactccag cttgtggtcg cacgcgcccc agcatagtca
     3661 gcctgaacac ggtcataagc ttggattgcc tcagttgact gttcttggta ttcttcctca
     3721 aagacaacat tctctagtgg cagtctcggt ttcatatcat gatgttgatt tggcacaccc
     3781 agtgccatcc caaagacaga ataggtgtag tcaggtaggt taaagagctc tgccacttct
     3841 tcagacttgt atcgaaccaa accgataatc acaccaccat agcccaagct ttcagctgcc
     3901 aacaaggcgt tttgtccagc aagagctgca tcgaccgaac taatcaagag accttccaca
     3961 ccttggggtt ggaaggtgtc ggtatgaagt ctggctccct tttctgctcg gttcaaatct
     4021 ccgacaaaga gaaggaaaac agcagactgg cgaatggctt cttgaggtac caattcatac
     4081 aaggcatctt tcttctcttg acttcgtacc acaatcacag agtaggattg gaaattcttc
     4141 caagatgatg ccatctgggc tgctgtcaaa atctcattta agtctacttg gggaatttct
     4201 tgctctttaa acctgcgcac tgaagtatga gccttcatca atttaatggt ttctgtcatc
     4261 gacggtttac tccttctaaa cgagtctcct cagccaaata acggatgcgt tccatgaccc
     4321 gtctggcttc ccaggtttcg tcatttccat gtttcacttt cgcaaaatgc ttctccaaat
     4381 cttcaaagtt gaagttggat gtgaaaaagg tcggtaaatt ttcctgcatc cgatattgga
     4441 gaatgacctg caggatttca tcacgcaccc aagcggtgga ttgctcggcg ccaatatcat
     4501 ctaaaatcag gacctcagac agcttaatct catccaccaa ggtcttaaca ttgccatcac
     4561 tgatagcatt tttgacatca atgacaaagc taggatagtg gaggagagtt gatgaaacac
     4621 cacgtttttc tgataaatca tgagctaagg ccgccaccat gaaactttta cccacaccaa
     4681 agtctccata taagtaaaga ccttttcgaa tagctggata ttgctccacg aaggctagta
     4741 gcttttcaaa aactggtaag cgccccaaat catccaagtc aacttgagcc aaactagctt
     4801 tcttgagact ggctggtaga ttgattaact tgagacggtt cttaatagcc gcttcttttt
     4861 cagccgcgat tagctcagga gtttcttcat atgaaacatc tgcatagcca tgattcttaa
     4921 ccaaaatcgg cttgtagcct ttggcaatat aatccgtatc cccacggaga aacttgtcac
     4981 gctcggtgat gtactgatta aacttggaga tactgcgatt taattcctct ggagtcaagg
     5041 attcttgctg gataaaagcc gcaacatcag ggtccttcat gattttctgg accaaatctt
     5101 gataataaaa acggctgggt tgacgtttga gtacgtctcc gacactttcc atctaatctc
     5161 ctcctttttc taatcgagct aatagttctt gcttcttacg ttctagttcc agacgagttt
     5221 cctcgctggt ttcattctta tattcaggat tactccattt aggaacattg gtttttactg
     5281 gggcagtctg attctgtttt tgtgtttttg ctttctgtcc tcgctcacgg atgcgcaaga
     5341 ctgccttttc tgccgaatga atcttttgat aggcatagtc attggctacc ttcatggcat
     5401 atttctcatt gatatttgcc gaatcgacct tattaaaggt caataaaaga atgatattga
     5461 tgacttcgtc cagcaagccc aagccagcca tctgttgcaa gagttctctt tctgtttggg
     5521 taatggttcc cttgcgtgtt tgcttgattt ctgccaagaa ctgcagggca gttttacttt
     5581 tggcttcttt gataatggtt gtttccttaa gactaaagtc agaggaaact ggtttttgag
     5641 caattttttc acgcatgcgt ttggttgaaa taacctgaga aacagctgtt gacttggcca
     5701 attgataggt ttcaaaccaa gtccatttct tctcctcggc aatagcaaag aggtttaaga
     5761 catcggactg ctcatccgca aaacgaagtc catctcgagc catcagctgg cgaaaatgtt
     5821 ccaagtcaaa atcattggcc actttcttct tgagaccaag gtcttcttga ctgcctagtt
     5881 ctgccaattc tggaaagact tgattgagtg agacaggtat ttcttcacca tcagcacttt
     5941 caactttcaa atcctccaca gcagagtcgc caatcttttt ctctaagagt ctgcgataaa
     6001 caggatgctc caagaagtct tgactagata gaggagcatg gagggctagc tgataaacat
     6061 cccccttttg atagagggtc aagagattaa aagcagataa gattttcaat gattttatca
     6121 gtctatccat cccaaagttg agatgattga ggatacttga aaaaagatat tcctttctac
     6181 cattatccca aaaactgatt gtataaagat aaaggctcag tgcctcctga ccgataatcg
     6241 ggaggtagca ctgtaccaga gatgaggtat cttgcgacac ccgattattc tttagataag
     6301 aaaaacggtc aattggcttc atttatcttt cctttttctt tttagaggac tgggtgattt
     6361 gttggagcaa gctctctaac tcactgacat ccttaaaact acgatagaca ctagcaaaac
     6421 gtacataggt aatctcgtcc aattcagcca actcctccat gacgagtgaa ccaatgtcct
     6481 cactttgaat ttcattttca tttcgaccac ggagtttctg ttcgatacga ttgactacca
     6541 tgttgatttc atcacttgac acaggacgtt tctgggctga gcggataatc ccattaaaga
     6601 ttttatctct ggagaattgt tcccgtgtgc catctttttt aacaaccact aaggttcttt
     6661 cttctactcg ttcgtaggtt gtaaaacggt gttggcactc gtcgcactct cgtcttctac
     6721 gaatggtgtt cccttcttct gcttggcgac tatcgataac acttgacttg gtagccccac
     6781 attttggaca acgcatcctt tccctcctta tcgttttctt ttcattatac cattttttaa
     6841 gcgattccca aaacaattct tctttttgct tgacaagttt tttgttttgt tgtattattt
     6901 aattaagaca aaaggataag agaaaggaga ctaagatgtc ctggacattt gacaacaaaa
     6961 aacccatcta tttacagatt atggagaaaa tcaagcttca gattgtttcc catacactgg
     7021 aacccaatca acaacttcca accgtgaggg agctagctag cgaggctggt gtcaatccca
     7081 ataccatcca aagagcctta tcagaccttg aacgagaagg atttgtctac agcaagcgaa
     7141 caactggacg atttgtgact aaggataagg agctaatcgc ccagtcacgc aaacaattat
     7201 cagaagaaga attggaacac ttcgtttcct ccatgaccca ttttggctat gaaaaagaag
     7261 aactaccagg cgtagtcagt gattatatta aaggagttta agcctatgtc attactagta
     7321 tttgaaaatg tatccaaatc atatggagca acaccagccc ttgaaaatgt ttctcttgac
     7381 attccagctg gaaaaattgt cggccttctt gggccaaacg gctcaggaaa aacaaccctg
     7441 attaaactaa ttaatggcct cttacaacca gatcaaggac gtgtcctcat caacgacatg
     7501 gacccaagcc cagcaaccaa ggccgttgta gcttatttgc ctgatacgac ctatctcaat
     7561 gagcaaatga aggtcaaaga agccctaacc tacttcaaga ccttctataa agatttcaat
     7621 cttgaacgcg cccatcatct acttgcagac ctgggcattg atgaaaatag tcgtctcaag
     7681 aaactatcaa aaggaaacaa agaaaaggtt caactgattt tggttatgag ccgtgatgct
     7741 cgtctctatg ttttggacga acccattggt ggggtggatc cagcagcccg tgcttatatc
     7801 ctcaatacca ttatcaacaa ctactcacca acttctaccg ttttgatttc tacccacttg
     7861 atttctgata tcgagccaat cttggatgaa attgtcttcc taaaagacgg aaaagtcgtc
     7921 cgtcaaggaa atgtagatga tattcgctac gagtcaggtg aatccattga ccaactcttc
     7981 cgtcaggaat ttaaggccta agcaaaggag attatttatg ttttggaatt tagttcgcta
     8041 cgaatttaaa aatgttaaca agtggtattt agccctctac gcagccgtgc tagtcctttc
     8101 tgccctcatc ggaatacaga cacaaggctt taaaaatcta ccttaccaag aaagtcaggc
     8161 tactatgcta ctttttctag ctacagtctt tggtggcttg atgcttacac ttgggatttc
     8221 aaccattttc ttgattatta aacgcttcaa aggtagtgtc tacgaccgac aaggctatct
     8281 gactttgacc ttgccagttt ctgaacacca tatcatcaca gccaaactaa tcggtgcctt
     8341 tatctggtca ttgattagca ccgctgtatt ggctctaagt gctgttatta ttctggcttt
     8401 aacagctcca gaatggattc ctctttctta tgtgattaca tttgtagaaa cacatctccc
     8461 tcagatcttt cttacaggta tatccttcct actaaatact atttcaggaa tcctctgcat
     8521 ctacctggct atttccattg gacagctttt caatgaatac cgtacagcac tcgctgttgc
     8581 agtctacatt ggtatccaaa tcgtcattgg atttattgaa cttttcttca atcttagttc
     8641 taatttctat gtcaattcac tggtaggact caatgaccat ttctatatgg gagcaggtat
     8701 agccattgtt gaagaactca tattcatagc tatcttttat ctcggaacct actacatctt
     8761 gagaaataag gttaatttgc tttaaataat ttttacctag atatgtaaca tactcataga
     8821 acaaaagaga ccaggcaaaa agtctttaca attagaaaac gcatagtatc aagtgttaaa
     8881 aatccttgat attatgcgtt ttttgtgagc tgacttattt cctttcacta tatcgcaaaa
     8941 tgaaataaga acggaacgat gggattttgg aattcaaatc aatttataag aatgttttag
     9001 aagtaatatt atcctattcc agattcagtt cactatacaa ttgagttttc aagcaacctg
     9061 tttacataat gtgtacataa ttaggttcgt gattccaccc ttttcacctt taaaaacctc
     9121 gctttcgcaa ggctcttcta tttataagat aaggcacgtt taaaggtttt ccaaatccct
     9181 aaatcatccg tttgaagaac gagactagca tacatgcgtc cgataaatcc tgttgctacc
     9241 accgcaaaaa tcactgtaat agcaagtgaa atccatgctt ccgctccctc cgcatagcca
     9301 ttaatcgttc gaaacggcat aaagaaggtc gaaataaagg gaatataaga accaatcttc
     9361 aagaggagat tgtcaccagc tgcacctaga gctgtcactc caaaaaaacc acccataatc
     9421 aaaatcatca aaggcgacaa ggctttccct gagtcttcag gacgagaaac catagatcct
     9481 aggaaggctg ccaagactac gtacatgaaa agactgatca aaataaagag caaggtattc
     9541 agtgagatag catctcccaa gtgatccaaa ataccagact gagccaagaa tggcaaatct
     9601 ttaaagagca aaacggcagc cagaccacct acaacataga tcccaatatg cgttaaaatc
     9661 actagaaaca gagccatcat ccgcgcatag aaatagtgac ttgcccttat gctagaaaag
     9721 acgacttcca taattttggt gcctttttca ctggcaactt cctgagctgt tacacccgca
     9781 taggtaatca gaatcatata aagaaagaat cctaaggcac ctgctgcaat tgtttgaata
     9841 aactttttat tttccttggc ttcatcaatc ttttctgtga attgaattgt ctgcgctaag
     9901 cgtttttcct gctcttgaga caaggaagca gttgaacgat taagctgatt ttgcagttca
     9961 ttgagtgtac ctgtaacctc aaatttaatt ccattttcaa gcgatgtttc gccatgataa
    10021 actgccttta gaacactatc ttcttgatca atggtcaaat aaccttttaa tttttcttct
    10081 ttaattgctt ctttggcact tgcttcgtct ttatagtcga agttaacacc atttacattc
    10141 ttcagtcctt ctgctacaga tggcactgtt gtcactactg ccactttatt atttttagcc
    10201 atagaagaac cttggagatg cccaattcct acagagattc ctaaaaagag gaacggcgaa
    10261 atcaccataa agaagaaact ccatgactcg acatgtcgaa gataggtttc cttgattaca
    10321 acccacatat ttctcatact tccactcctg attctagttt aaagatttca tcgatagttg
    10381 gcgcttgttg gtcaaatgtt gcgatatatt gaccttgagt caagattggg aagagttccc
    10441 ttccagcgct ctcatcctcc aaaatcaatt tccaactgcc ttgtttggtc aagctcacct
    10501 gtttgacatg aggaagattt tccaattctt ccttgcttcg ttcacttgaa acaaagagac
    10561 gcgttttccc gtattgattg cggacatcct gaactggtcc gtgcaagacc acacggccat
    10621 ctcgaatcat cagaatatcg tcacaaagtt cctcaacatt ggtcatgaca tggtcagaaa
    10681 agataatggt tgctccgcgc tctttttcct gaaaaatgac ttgtttgagc aattctgtat
    10741 taactgggtc caatccacta aaaggctcat ccaagataat caggtctggt tcatgaatca
    10801 gagtaataat gagctgaatc ttctgctgat ttccttttga cagactcttg attttatctg
    10861 tcagctttcc ttttacttcc aacctcttca tccattgagg gagtttttct ttgacttctt
    10921 tggcatccat gccttttaga gtcgccaagt agcgaacttg ttcaagaact gtcaatttag
    10981 gcatgagact gcgttcttca ggcagataac caatccgagc atagatctcc tgacgaatat
    11041 cctgaccatc cagaccgatt tctccctgat attctaggaa ttttaaaata ctatggaaaa
    11101 tcgttgtttt tccagcacca ttttttccga ctagtcccaa aatacgacct ggtcgcgctt
    11161 gaaagtcaat accaaacaaa acttgcttgg atccaaaact tttctctaga cttcttactt
    11221 ctagcatctt tcacctccga aatttcttgc actcattata ctcctttttg atagccttta
    11281 caatgttttt tgtccatttt tagaagacta ttgctgtgta aaatatggcc tggagcactt
    11341 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgtagactg ctcaaagtac
    11401 agctttgagg ttgcagataa aactgacgaa gtcagctcaa aacactgttt tgaggttgtg
    11461 gatagaactg acgaagtcag taactatacg tacggcaagg cgaagctgac gtggtttgaa
    11521 gagattttcg aagagtatta gtgataaatc cattatacag cagcaaactt aatttatacc
    11581 ttccgctcct caactgtcta tttttaatcc tgaattgtta tttgagtaac tcctttttcc
    11641 tcgtaaagtt ttcttcctct aaaacttctg gaaaaaggct aatagtttca gacaacattt
    11701 ttataagaaa caagttcatc tgtcatttca agaaggagta atcctttatc tactaatgga
    11761 cggaacagaa ttcaaccgct tgtccgatat gttttctaag gattatatag taaaatgaaa
    11821 taagaacagg acaaattgat caggacagtc aaattgattt ctaacaatgt tttagaagta
    11881 gatgtatact attctagttt caatctgcta tatctattat gcacacccct ataggatcta
    11941 atgaaaatca caacaggctc attcatagat agttacctca ggaaactaag aaaacgacta
    12001 caaaggaagt cgcattcatc gaaaagtgga ttaacaacta tcctaaaaaa tgcttgaact
    12061 acaagtcccc cagagaagac ttctggatga ctaacttgaa cttgaaattt agcaataatt
    12121 aattcaccat ctaactatat ttagtaatta tttcagaact gattaatatt aaaattaact
    12181 aacaattcaa aggattcata ctagccataa attacgtcca tcagagagag actcttacta
    12241 cttttagatt ttagtctttc tagcttcaga atacatctaa actttaggga aaatgactat
    12301 tcgaaagcgc gaatgcctca aaattatctc agataagcta ttcgaaactt agaatgcttt
    12361 taaatttatg gaattgcgat tattcgaaac ctagaatgca tataaccttt agttgacaga
    12421 cctattctaa gtctcgaagg gctatttact ttctattcct tatcaaaaaa gactcattcc
    12481 ccctttctcc tccaaaatat ggtatagtag aaatatacta tctatgagga gtttacatgt
    12541 cacaggataa acaaatgaaa gctgtttctc cccttttgca gcgagttatc aatatctcat
    12601 cgattgtcgg tggggttggg agtttgattt tctgtatttg ggcttatcag gctgggattt
    12661 tacaatccaa ggaaaccctc tctgccttta tccagcaggc aggcatctgg ggtccacctc
    12721 tctttatctt tttacagatt ttacagactg tcgtccctat cattccaggg gccttgacct
    12781 cggtggctgg ggtctttatc tacgggcaca tcatcgggac tatctacaac tatatcggca
    12841 tcgtgattgg ctgtgccatt atcttttatc tagtgcgcct atacggagct gcctttgtcc
    12901 agtctgtcgt cagcaagcgc acctacgaca agtacatcgg ctggctagat aagggcaatc
    12961 gttttgaccg cttctttatt tttatgatga tttggcccat tagcccagct gactttctct
    13021 gtatgctggc tgccctgacc aagatgagtt tcaagcgcta catgaccatc atcattctga
    13081 ccaaaccctt taccctcgtg gtttatacct acggtctgac ctatattatt gactttttct
    13141 ggcaaatgct ttgacacgta aaaaatccgt ttggtttccc aagtggattt ttaaagcgta
    13201 gattaactat agcttgatac taaatatact ttggtatgga aatcatgcat atttttcgat
    13261 agtgaagcga ggacttacct agcctttcca ccgtgataga aacacctgaa atctaatggt
    13321 ttcaggtgtt cggaaacttt gagcctagtg tctcaaagtt taggtatgga atttcgaaga
    13381 aagtcgctac cgtccgtaat cacttaagga aaggctcaaa aatattgttt tcaaccacaa
    13441 aatccgtttg gtttcccaag cggattttgt gctttatttt gaaacttctt ttgcaagaac
    13501 aaagttccca agtgtggcag aaccatttcc tgcgactgct ggcgtcacga tatagtcacg
    13561 cacatctggt actggtaggt aaccattaag aagagatgta aatttctcac ggacacggtc
    13621 cagcatatgt tgttgagcca tgacccctcc accaaagaca atcacgtctg ggcggaaagt
    13681 cactgtcgca ttaaccgcag cttgagcgat atagtaggct tgaacatccc aaacagggtt
    13741 gttgagttca atagtttccc cacgtacacc tgtacgagct tccaaacttg gaccagctgc
    13801 atagccttcc agacatccct tatggaaagg acaaacaccc ttaaactctt tttcaatatc
    13861 cattgggtgt ctagcaacat aataatgacc catttcaggg tgacccacac caccgataaa
    13921 ctcaccacgt tggatgacgc ctgcaccgat acctgtaccg attgtgtagt aaaccaagtt
    13981 ttcgatacga ccaccagcat tgttacgggc aaccacttca ccgtaagcag agctgtttac
    14041 gtctgttgtg aagtacattg gcacgtttag ggcgcgacga agggcaccaa gcaagtccac
    14101 atttgcccag tttggttttg gagtcgtcgt gataaagcca taagtttttg agtttttgtc
    14161 aatatcaatc ggcccaaatg aaccaactgc aagaccagca aggttatcga attttgagaa
    14221 gaactcaatg gttttatcga ttgtttcgat tggagttgtt gttggaaatt gtgttttttc
    14281 tacaacgtta aagttttcat caccgacagc acagacaaac tttgtaccgc cagcttccaa
    14341 gcttccatat aattttgtca tgataaacct cttgttttta ttttctttat tatagcatac
    14401 ttcgaaagtc taaatgtctc tattttttag attttcctct gtaaatctta ctatctaata
    14461 aaaacgaaca aacatgtcat ttgttcgttt tcacattaga gaggattgat tagattttca
    14521 cttcgatcac agcatccccc ttcgcaactg aacctgttgc gactggagct actgaagcgt
    14581 agtcagctgt atttgtaacg ataaccattg ttgtatcatc aagtccagct gtagcgattt
    14641 tatttgagtc aaatgttcca agaacatcgc caactttcac cttatcacct tgagcaactt
    14701 ttgcttcaaa accgtcaccg ttcatagata cagtgtcaat accaacatga atcaaaactt
    14761 cagcaccatt tcttgttttc aaaccaaaag cgtgccctgt tggaaaggca attgaaactt
    14821 cagcatcagc tggtgcatag accacgcctt ggcttggttt cacagcgata ccttgtccca
    14881 tagctccact tgagaagact gggtcattga catcagcaag agcgacaaca tcaccgacga
    14941 taggagttac aagtgtttca ttttgaagag ctgctggcgc aacttcttct ttttcttcag
    15001 ccacttcagc ttgttttgca gctgcagttg cgtctacttc atcttcgtaa ccaaacatgt
    15061 aagtaagagc aaaaccaagg gcaaatgata cagctaccat aagaaggtat tgtggaagtt
    15121 gtccgttacc aacataaagc attgtaccag ggatgatggt gataccatta ccagtaccag
    15181 caagtccaag gatagaagcc aatccaccac cgattgcacc agcaatcaat gaaaggaaga
    15241 atggtttacg gaagcgcaag ttcaccccga agatagcagg ctctgtaata cctaggaagg
    15301 cagaaagagc agccgggaaa gcaagtgttt tcagttttgg attttttgtt ttaacaccaa
    15361 ccgcaacagt agcagcacct tgagctgtca tagcagctgt gatgatagcg ttgaatgggt
    15421 tagcatggtc agcagcaagt aattgcactt caagcaagtt gaagatgtgg tgcacacctg
    15481 acacgacgat caattggtga accccaccaa tcaagaaacc accaagacca aatggcatgc
    15541 taagaatcgc ttttgtagca ataaggatgt agttttcaac aacgtggaaa actggtccaa
    15601 tgacaaagag tccaaggata gacatgacca aaagtgtcac gaatggtgtt accaagaggt
    15661 caatgacatc tggaacaacc ttgcggacag ctttttcaaa tttagctccg acaaccccga
    15721 tgatgaaggc tggaagaacg gaaccttgca aaccaacaac agggatgaaa ccaaagaagt
    15781 tcatcgctgt tacttcacca ccttgagcaa ctgcccaagc gtttggaagt gagccagaga
    15841 caagcatcat accaagaacg ataccaacgg caggatttcc accaaataca cggaaggttg
    15901 accacacaac caaacctggc aagatgatga aggctgtatc tgtcaagatt tgtgtgtaag
    15961 ttgcaaagtc acctggaagt ggcatttcaa gagcgttgaa aagaccacgc acacccatga
    16021 agagacctgt cgctacgata actgggatga ttggaacgaa aacatcacca aaagtacgga
    16081 tagcacgttg gaaccagttc ccttgtttag caacttctgc tttcatgtca tccttagatg
    16141 atgttggtaa tccaagtaca acaacttcat cgtacatttt gttaactgta cctgtaccaa
    16201 agataatttg gtattgccct gagttaaaga aagcaccttg aactttttcc aagttctcaa
    16261 tcacttcttt attgattttc tcttcatctt tgaccatgac acgtagacgt gtcgcacagt
    16321 gggcaacact attgacattt tcacgtccgc ccaaggcatc gatgactttt tttgcaattt
    16381 cctgattgtt catttgcaaa aatctcctta tataacattt tgttcttgtt tgaaagcgat
    16441 tttattcgcc cttacgacta ttattttatc atgttttaaa aatatgtcaa gcgttttgca
    16501 gaaaaaatat tctatctact tagtgggcaa gctttagatt gattgttttt gactgtttca
    16561 tcaggaattt cttgaaaaat aagtttgaaa ccttggttaa aaagtctttt atttcattat
    16621 ctttcacatt ttcgtaaaaa tttgattgat ttcctgtatt tattttatga taatcgtttg
    16681 acagtttttt ctctttttta acataaaggg cttgcatttt ttatcgaaaa cagttactat
    16741 taaaagtgat aagatttttg gaggaatgaa tggaatggac aactgagcgt cgttacagac
    16801 tttatcaaga ttggacgcaa gaagaaattc aacatataaa ggaaaatatg gcacaatctc
    16861 catggcatac tcattaccat gttgagccaa aaacaggact tctcaacgac ccaaatggct
    16921 tttcttactt tgatggcaag tggatcctct tttaccagaa ttttcctttt ggtgcagccc
    16981 acggtttaaa atcttgggca cagctagaaa gtgatgattt ggttcacttt agagaaactg
    17041 gagtcaaagt tttgccagat actccattag atagtcacgg tgcctactct ggttctgcca
    17101 tgcaatttgg cgataactta ttcctatttt atacaggaaa tgttcgcgat gaaaactgga
    17161 tccgtcaccc ataccagatc ggtgctttga tggacaagga gggtaagatt acaaagattg
    17221 acaagatctt gattgaccag ccagcagact ctactgacca cttccgcgat ccacaaattt
    17281 ttaactttaa aggtcaatac tatgctgtcg tcggtggaca ggacttggag aaaaaaggct
    17341 tcgtccgtct ctacaaggct gtcaataacg actacacaaa ctggcaagca gttggcgacc
    17401 ttgactttgc taacgaccgt actgcctaca tgatggaatg tcctaatctg gtctttgtag
    17461 aggaacagcc tgtccttctc tactgtccac aaggattgga taagaaagtt ctagactacg
    17521 ataatatctt tccaaatatg tataagattg gggcttcctt tgaccctaaa aatgccaaaa
    17581 tggtagatgt gtctcaactt caaaacatgg attacggttt cgaagcctat gcaactcaag
    17641 ccttcaacgc tcctgatggg cgtgctctag cagttagctg gcttggtttg ccagatgttt
    17701 cttacccatc tgaccgtttt gaccaccaag gaaccttctc tttggtcaag gaactcacta
    17761 tcaaagacga caagctctac cagtatccag tcgctgctat taaggacctt cgtacttctg
    17821 aagaagcctt ctcaaaccgt tcccaaacca agaacactta cgaacttgaa ctcaacttgg
    17881 aagctaatag ccagagcgag attgtcttac ttgctgataa agaaggtaag ggactttcaa
    17941 tcaactttga ccttgtaaac ggtcaagtga cagtggatcg tagccaggct ggagagcagt
    18001 atgcccaaga atttgggata actcgttctt gccctatcga gaatcaggct actactgcta
    18061 caatcttcat cgataactct gtctttgaaa ttttcatcaa taaaggagaa aaagtatttt
    18121 ctggtcgtgt cttcccacat gcggaccaaa atggtatcct gatcaaatct ggaaacccaa
    18181 ctggaactta ctatgaatta gattatggtc gcaaaactaa ctgatgtcgc caaacttgca
    18241 ggcgtcagtc ctactaccgt ttctcgggtt atcaataaaa aaggatatct atctgagaaa
    18301 accatccaaa aagtcaatga agccatgcga gaattgggct ataaacccaa caacctggct
    18361 cgtagtctgc aaggaaaacc agctaagtta atcggcttga ttttccccaa tatttccaat
    18421 gttttctatg cagaattgat tgataaattg gaacaccaac tcttcaaaaa tggttacaag
    18481 accatcatct gcaacagtga acatgattct gagaaggaac gtgaatacat cgaaatgttg
    18541 gaagccaatc aggtggacgg catcatttct ggtagtcaca acctaggaat cgaagactac
    18601 aatcgtgtga cagcgccgat tatttccttt gaccgaaacc tatcgccaga catccctgtc
    18661 gtctcctctg acaactatgc tggtggggtt cttgctgccc aaaccttggt caagacaggt
    18721 gcccagtcta tcatcatgat tacagggaat gacaattcca attcgccaac cggactgcgc
    18781 cacgctggtt ttgcatccgt actcccaaaa gctcctatta tcaatgtttc cagtgacttt
    18841 tctcccgtca gaaaagaaat ggaaatcaag aatatcttga cccgggaaaa accagatgcc
    18901 atttttgctt cggatgattt gacagctatt ctggtcatta aaatcgctca agaattgggc
    18961 atttctgtcc caaaagagct caaggtcatc ggctatgatg ggacctactt tatcgaaaat
    19021 tactaccctc aattggctac tatcaagcaa cctttggaag agattgcttg tctcactatt
    19081 gatcttctct tgcaaaagat tgaaggcaag gaagtcgcca caactggtta cttcttacca
    19141 gttacgctat taccaggaaa aagtatttaa acacaagaaa actcagaccg attcgtctga
    19201 gtttttatga tcttaaattt tcgagatagc gctgggctgt ctctaggtta aaggttttat
    19261 ctgagatgag gcgctctact aggggagcaa cttcagattc actagcccca gctaggagag
    19321 ctagggattt ggcctgtagt ttcatgtggc cttgctggat gcccgtactt accaaggctt
    19381 tgagggctgc aaaattttga gcaagaccga tggacacgat aatctgggct aattctctgg
    19441 cagaaggatt tcctagtaga tcatgactga gagctacacg tgggttgagg ccgatagagc
    19501 cacccttagt cgctacaggc atgggcaggg tcatctcacc gaccaattct tctctttcaa
    19561 ggtccagcgt ccagcagcta agaccttgat agcgtccatc tcgactggca aaggcatggg
    19621 ccccagcttc gatggcacgc cagtcattac cagtggcaat caaaatcgca tcaataccat
    19681 taaaaattcc tttattatga gtagcagctc ggtaaggatc agcctgcgca aactgactag
    19741 ccaacgcaat tttctccgca atctctcgtc cttgatcctt ttggcggctc aagtagcgaa
    19801 aggcgatgcg acagcttgca gtcaccagag aatcagtcgc gtagttggac aggattccca
    19861 tgagactctg tccctgactg agttcttcta agactggttt caaggcttcc agcatggtgt
    19921 tgagcatatt ggcacccatg gcttcctggg tatcgacatg aatataaaca acgagaaagt
    19981 ctggttcgcc ttttatctgc tcgacatgca gatcacgcgc cccaccccca cgtttaacga
    20041 tagaaggata ggcttgattg gcaagctcca agagctccgc tttcttgctg gcaatcttct
    20101 cttgcgctag tttaggatta gcaacttgat aaagggctac ctgcccaatc atctggcgct
    20161 gatggacttg tgcagtaaaa ccacctgcac gcttgatgat tttgctggca tagctggccg
    20221 ccgcaaccac agagggttct tctgtcacat agggaacggt gtattcctga ccgttgacaa
    20281 gtacctccgg aaccagcgaa taaggcagag aaaaagttcc caccacattc tcactcagct
    20341 ggtctgccac agtcacactc atctgttcat ccttctccag actagcttgt ctctcaggac
    20401 taaggagcgc ctgagctttt agcagctcga ggcgctcttg gtatgatttt ttagaaaatc
    20461 cattccaact tatcttcatt atttttcaac cttgctataa cggcgttggt ggtcaagaat
    20521 ttcaaccaag gcaaaatctt gattttcata gccagcaaac tgggcagagt ttgtttcatc
    20581 caagtttact tcctcaaaaa agaccttttc atagtctgca acggataggg cagttcgttg
    20641 gttgagcttg ttcaagcggt ctttatccaa ataagcttca tatccttcaa ccaattcacc
    20701 actgaagaac tcagccacag ctccacttcc gtaactataa agggcgattt tatccccagc
    20761 tttcaagcta tctgtatttt ccaagagaga caaaagtcca aggaaaagtg aacctgtgta
    20821 gatattcccc accttttgac tgtagagaat agactggtca aaatgctttt gtaagaggtc
    20881 ttttttctct tgaggcaggc tcttatccat gatttttttc aagcctttta gcgctaattt
    20941 aggataaggc aagtggaaac aaacagccgc aaaatcatcc aaagtaagct ggtagcgttt
    21001 ttgatattca agccaagtcg ttttcaaact atccaagtat tgttgggtag aatagacacc
    21061 atttacataa ggagttgtcg agtaatttgg tcgccagaaa tccatgatgt cacgggtctg
    21121 agctacattg tcattattaa aggccatcat gcgtggattt tgtgtaatca acatagctac
    21181 acttccagca ccttgagttg gttctcccgg agtttcaata ccatatttgg caatatcact
    21241 ggcaatgacc aagaccttgg actccggaga attttccaca tgcaatttgg cataatggag
    21301 ggcagctgtc gccccatagc aggcttcttt aatctcgaaa ctacgagcaa agggctggat
    21361 gcccagcaag ccatgcacaa agacggccgc agccttactc tggtcaattc ctgactcggt
    21421 agccacaatg accatgtcaa cttcttgtct ttcttgctca gttaaaatag agtcactagc
    21481 actggccgcc aaggtcacga tgtcctcagt taggggcgca atactcaatt ccttgagtaa
    21541 gagtccttta cttaattttt cagggtcaat tcccctcgct tctgctaagt cttgtaattt
    21601 caagacatat tgactggtcg caaaaccaat cttatcaata ccgattgtca tatttacctc
    21661 tgttttatca ttcatgtaaa aaatcgttct atactatttt atcacaaatg gcagtaaaag
    21721 agagaaaaaa gacttgattc accaaatcaa gcctcttatt ggtcatcatt ttaaagaatg
    21781 attagttgct agagagttca ccgatataag tagctttata agctccattc acagttatca
    21841 gctcctggag gatcaaattt cctgagtaaa tccttcccat ctcatctaca aatttttgat
    21901 aaaactgact gatcggaatt tctctgacat ccttatcaaa tgtcttatca agtgttttac
    21961 taaccttctc agcaatcaat tgatgctctt gccatccact ttgaaactct gagcccgaac
    22021 tagaaaccat gactgggata aacaacaagg tcagtagatt tacagacaat aaggaaagta
    22081 gtagacttcc tgcaaaacta gaatcctagt tcatgattga taatgccagc aatcaaattc
    22141 attcgtaatc cgaagcgttt acgatgattt cgataggttg ttgaaaacat tttaaacgtt
    22201 tttactttgg caaagatgtt ctcaaccttg cttctctcct tagatagcgc atggttacag
    22261 gctttatctt caactgttag cggcttgagt ttgctggatt tacgtggagt ttgtgcttga
    22321 ggatatatct tcatgagccc ttgataacca ctgtcagcca agattttacc agcttgtccg
    22381 atatttctgc gactcatttt gaacaacttc atatcatgac aatagttcac agtgatatcc
    22441 aaagaaacaa ttctcccttg acttgtgaca atcgcttgag ccttcatagc gtgaaatttc
    22501 tttttaccag aatcattcgc taattgtttt tttaggacaa ttgatttgta cttccgtcgc
    22561 atcaatcatt accgtgtctt cagaactgag aggagttctt gaaatcgtaa caccaccttt
    22621 gaacaagagt tacttcaacc cattggctcc gacggagtaa gttgctttcg tggataccaa
    22681 aatcagccgc aatttcttca taagtgcggt attctcgcac atatagaaag cgttgttaat
    22741 ttatttatct catttttcag aaaattcttt tatttctgta aagtctacga tactcgatgt
    22801 gtttttatat aatgatacag tctgagaatc actgttccgc tagccattcc aatagagatt
    22861 accaaagcca acatgacaac caaggtcgca cttgccagtg ctttattata gtcccctgtc
    22921 acaaaaaagg cagttgttcg gtaggagaga taacctggaa ccagcggtgc caaaatggcc
    22981 aagataaaga ccacagcagg tgtcttataa agaatactta aaatctggct gacacaagaa
    23041 ccaataatgg ctgcaatgaa ggtagctaca atgacattgg tcggttcctt gagcaagaga
    23101 tagattagcc agacagtcat gcccaaaatc cctccaggta agagcataga ccgttgcaca
    23161 ttgagtacga ttaaaaaagt gataatggca agaaaacttg ctactgcttg taataaaaag
    23221 gttgttagtg tcatattagt tcatcaatac caaggcgaca gaagttcctg cccctaaagc
    23281 gagggtaatg agcagggatt caaacatctt actcatacca gagtttatgt ggttggtcat
    23341 aatatcacgg accgcattgg tcaaggcaat acctggtaca aacggcatga ccgcaccagc
    23401 tataatcaaa tctgccgttg aaggaaaacc tgtgtagcga gcccaaaact gggcaattat
    23461 cccaaagaca aaggctccag caaaggctgt cacaaaggga attcggataa atttttccac
    23521 atagagggaa aaggcaaaac caaataaggt cgccactcct gccccaagtg cgtcgtagat
    23581 atttccgcta aacataactg aaaagaaagg agcactaaag gtcgcagcca gagttacctg
    23641 caacttagta tagggaaggg gtttggcttg caaggccgtc aattgcttaa aggctgtttc
    23701 taagtcaatc tgccccccaa ctagctgacg agaaatctgg ttcacatcgc agactttttc
    23761 gatgttataa gaagaggagg tcacgcgctt catgcgcgaa atattggtat tttcaataga
    23821 gaaaaagata gcggcaggca tggcaaggac attgcaatcc acaatcccct gcgaatgcgc
    23881 gattcgaatc atggtatctt ctacacgatg gatttctgag ccacttttaa ggagaatagt
    23941 ccccgctagc ataatcacat caatgacggc atttaattct tttgattctt ccatgctttc
    24001 ctccttttat caactccctc tattctatca caaatccgga ctcaaaaaaa atctttgcca
    24061 tgaaatcatg acaaagattg attactcatt ttgattatcc atctgctttt aaggagtagc
    24121 tgaagttgtt ttaggtttgt agattgaaat cttgactcta gtcttattta ggtctacctt
    24181 ttcacctgct ctaggacttt gttcaacaac catgccttct acactacctg caggcgctgt
    24241 cgtcacttct acaacttcta tattagcttc cttaatccca acaatttgaa tcaaattgtt
    24301 cttagtaaac tccaagctgg aaccaatgta actcggcatg gcaacacttg taactttttt
    24361 agctactgtc aagacaattt gagtaggttt actcacatca taagtcgttc cggcacctgg
    24421 actttgtttc ataatcgttc ctggttcgct ttcgctggac tcttcttcct ctatcttaat
    24481 caaattctca ggaaccttct tctgcttgag ttctgagatt acttctgtag agttccgtcc
    24541 aatatagttc cctaattgaa tcgtcgtagc ttttttagct actgtcaaaa caatttgagt
    24601 tgccttgctc aagtcatagg tcgtaccttc tggtagactt tgcttcaaga ccgttccagc
    24661 ctcactctca ttggactctt cttcctcaat tttaatcaaa ttatctggaa cttttttctc
    24721 ttttaattcc gcgataacat cagaagattt ccggccgaca taattactaa tttggaagga
    24781 ttgtttgcct gatgagacaa ccagattgat tttcgttcct tcttttcgac cagttccagc
    24841 gccaggatct gtacggataa tccgcccttc ttccaccttt tcactagcct ctgtcttctc
    24901 ctcaccaatc tcaaaattgg cttttttgag cgttgccttg gcctctgcaa ctgtctgacc
    24961 tgccacatcc ggaatggcaa tggttgcagg agttctggat aagatccaaa taagagaagc
    25021 tgccaccaat acaaggctgg ccaacaaaat caggtaacgc atcttaaatc tatgtttttt
    25081 cggtgcttgt ggttggtaag tttcctctgt cacagcctgg cttgggtttt tgattgattt
    25141 gtgttctgtc tgcgcttgaa ccttaggaat agatgtcaag gtactctgag aaaccttcgg
    25201 caaggtcttg gtatctgcct tgctcgtttc atcaaagatt aacttacttt catttctacg
    25261 attgtaggac aagctactag acaagtccac atacatctct gaaaccgatc ggtagcgatt
    25321 ggtcaacttt ttagcagttg ccttgataat aacattttct aaagcctgag gtacagatgg
    25381 attttctgca ataacggacg gcaggggttt ctggaaatgc tggagggcaa tggtcaccgc
    25441 gctatccccg tcataaggga tatggcctgt caacatctca tagaaaataa tccccatggc
    25501 atagatatca ctctgcacag tcgccttaga accacgcgcc tgctctggtg acaagtaatg
    25561 aactgagccc aacatcgagt tagtctgggt cagacttgtc tctgcaaagg ctacagcaat
    25621 cccaaagtct gtgaccttgg cagtcccatc tggtgtcaaa aggatatttt gaggtttcaa
    25681 gtccctgtga acaattcctc gagtatgggc caagcgcata gccaagagaa tttgtcccat
    25741 gatacggacg gcttcttcat tagaaagagg ataatgttcc ttgatatagc gtttgaggtc
    25801 tagtccagca acatactcca ttgcaagata ctgttgaccg tcttcctcac caatatctgt
    25861 tatccgaacg atatgaggat ggtctagatc tgccatagct ctcgcttcac gctgaaaacg
    25921 agctacagct atcgggtccg tctggtagtt ggtcctcaga accttcactg ccacttcttc
    25981 cccatctaag attaagtctt tggctaggta aacatccgcc atgcctcctc gaccaatctg
    26041 tttgacaatc cgatagcgtc cggcaaaaat cttgccgatt tggatcattc ttcatcctcc
    26101 tcgttcatag aaacaagggc aaccgtaatg ttgtctaaac ctcctgcatt gttagcaaaa
    26161 cgaacaagtg tctccgtttt atctgctaaa ggaatatcac tggttacaat atcacgaatc
    26221 tcactgcctg aaatcatgtt ggtcaagccg tcactattga gcaagagata gtcacctgac
    26281 tcaaggataa ctgtcccaaa atcaggctga atttcatctt tttgcccaat agactgggtg
    26341 ataatatttt tttgcggatg agcttctgcc tcttctggtg tcaattgacc agccttgagc
    26401 aattcattaa ccaaggaatg atcgctcgtc aactgatggt attcttctcc acgaatcaag
    26461 ccgatacgcg aatcaccaat atgagcatag atagcctgat tatcaataat agcaaggact
    26521 tccaaagtag ttcccatgcc tctgtaagct tcatcctgac caagctggtg aatcttttga
    26581 ttttcaattt ctaggtaatg ggcgaaccat tcacgcactt cattgactgt atcgatctgg
    26641 gtatcaaccc aagctacacc caggtctgtg accgccattt cactagcgat attccctgca
    26701 cgatgacctc ccatcccatc agctaaaata atcatggtac gtccagctct attgacatag
    26761 tggttgacat agtcttggtt atttgttcgt ttctgaccaa catctgttaa taatgaaatt
    26821 tccatgtgtc agttccttcc taatccgata tcttgcgaaa ttgactgatg aagaatccat
    26881 cacttccata caattcaggt gtaatgagga tacagccgtc tttcatgata tccttacatt
    26941 catgttctag ttttacctgc tcgaactcgg gatgactctc taaaaaggcc ttaacgactt
    27001 gaaaattctc ctctgagacg atagtgcagg tgctataagt tattatacca cctttgccta
    27061 gtatttgaca aacactacct aatatttcta actgaatttc ctgcaaggac gcgaaatctg
    27121 ccgtttcttt attgtatttg atatctggtt ttcggcgcaa aagaccgatt cctgaacaag
    27181 gagcatccac caaaatctta tcaaaggaat cctggtcaaa aaactcatgc acctttctgg
    27241 catccaattt ttgagtttga acccgatctt caactcccag acgttgggca ttttcttgaa
    27301 ttaaatccaa cttgtggtcg tacaagtcca gagcagtaac ctgacctgtc gtaagataag
    27361 aggctatatg ggctgttttc ccacctggag ccgcacaggc atcaagcact cgctcatcac
    27421 cttgtaaatc aagcgtcgga gcaaccagct gactggactc gtcttggatg gtaatggctc
    27481 catccgcaaa caaattatgc cctgcaaaat gcccctgctc cttaaccaga ccagtggttg
    27541 ctaaaaggga atcattcgcc tccaacaagg cttggatttc ctcttttcga cttaggtctg
    27601 ttacacgaat actggctttg tttcgcacta acaggctttc aaagatggct tttgctctct
    27661 cctctccgta ttcttccttg agtttggcaa ctagccaaac tgggagagaa taggcaatgg
    27721 agtcacgctt gttttttcgc ttgatgctag caatatctgg ccagccttca cgcaagatac
    27781 ggcgaaggag ggcattgacc aatttttcac tgcctttttt acgaagtttg gccaattcca
    27841 ctgcttcatt gaccacagca tgatctggaa tcttgtccaa atagcggagt tggtaggcac
    27901 tcatgagaag aaggacatag agccagctgt ctaactggtc tctgtcttcg ataaagtggg
    27961 ataggtacca ttccagagtc agtttacggg ctaccgttcc atagaccagc tcggtcacta
    28021 agcccttgtc tgctgccaaa agttgactcc cctttagatg cttatttaag gcgatatttg
    28081 agtatgcttg gttcacaaaa acatcctcta gcactgctag agctaaactt ctagccgttt
    28141 ctactttagt caccaaatcg ttctcctaca gtcaatgtac gtccaactcc gttgaggaag
    28201 gaagcaatgt ccatcttagg cttaccagct ggctgcactt gtttgaggga tagagcccct
    28261 tcagccgttg cgacaatcaa ttctttcttg ccgatagaga gaatctcacc tggatttccc
    28321 tgaccttcta ctggtagggc ttcataaatc ttaaagcggt cgcccttaag gaaagcatgg
    28381 gcaacaggcc aggggttcat tccacgaatt tggttaaaga gttgacgatt ggttttgttc
    28441 cagtccagtt tttcttcctc tggctttata tttggagaga aggtaacctg actcgtatcc
    28501 tgcggttcag gtttgatatc accagcaata taggcaggca gagtgtccaa aagcaaatca
    28561 cgaccaacta gcgccaattt ttcaaacaag gtgccaacat tgtcctcatc tgtgatcgga
    28621 atgctgcgac gagaaatcat atctcctgca tccatttcct taaccatttc catgatggtc
    28681 acaccagctt cctcatcccc ttgaatcaag gcataatgga taggcgcacc accacggtgt
    28741 ctaggaagga gggaggcatg aacgttgaca gcaaagtcca tgctatcaag gagtttgctt
    28801 gggagaaact gcccaaaagc agcagtcaca attccatctg ctcctagctt cataagttct
    28861 tccatctctg gacttccaga taatttttca ggttggtaga tagatagtcc tgcttccttg
    28921 gcagcctgct tgactggggt ttcttggata acttttttac gaccaacagc acggtctggc
    28981 tgggtcacaa cggctagaat ttcgtaacgg tcatctgtca aaagtccttt taagactgtt
    29041 gctgaaaagt cgggggtccc cataaagatt agttttgtca tatcttctcc ttcttataaa
    29101 aattgctgcg gctcatggtc aatgctgaga cggagctcac tattttcccg ttcttgagtc
    29161 aaggccaaga cctggttgag ggtcggcccc agctcatctt ctaaacggta tttaattaaa
    29221 atctggtaat gatagaggtt gtgggtacgg gcaatcggtt ttggcgttgg ccccagaatg
    29281 ggactggtct ctgacaagcc tgaccgcaaa atgttcatga cttcataggc acgtttgaaa
    29341 acctcttctt ctttcttgtg agaaagggta ataccaatcg tgaaatagta aggtggatag
    29401 ccgagttgtc gtctgattcc catttcatag gcataaaagc cttcgtaatc ttgatccttg
    29461 gcaaatcgaa tagcatagtg ctgcgaattg taggactgta tcaagacttg acctgctttt
    29521 tcagcccgac ctgctcgacc tgccacctga gtcaagagct ggaaggttct ctcagaagaa
    29581 cggaaatcag gcagattcaa ggccgtatcc gcatttagaa ctccgactag ggtaacattg
    29641 ggaaaatcca aaccctttgc aatcatctga gtaccaagta aaatatccgc ttcccctcgc
    29701 ccaaactggt caagcaaggc ttggtgactg cctttctttc gagtcgtatc cacatccatc
    29761 ctcaaaatgc gagcttgggg aaagagttct gctagctcat cataagcctt ctgagttccc
    29821 gtcccatagt aacgaatact gcggctctta cagttaggac agacctgagg aatatccttc
    29881 gagaaaccac aataatggca gttcatagtc ttggtatcca tatgcaaggt cagagaaata
    29941 tcgcagttgg gacaagtatc caccgtccca cactcccgac acatgacaaa gctagaataa
    30001 ccacggcgat tgagcatgag aaccacctgc tcttttttaa ccagacggtc ttggatagcc
    30061 tctagcaaag gaggcgtaaa gtttgacgtc tcattttgtc cgatatagtc tcgaaagtca
    30121 atcacttgaa cctcagggat tgtagccaaa ggattagcac gttgggttag acgtaagtgt
    30181 tgatagacgc ctttgccagc acgtgcccgg ctctctaagc tcggcgttgc agatccaagt
    30241 accagagttg cttgattata ctgagcccgt aaaatagcta catctctggc atggtaacgg
    30301 ggattgctgt cctgcttata agccacttca tgctcttcat caataatcat gacacccaga
    30361 tttttcagag gagcaaagat agcagatctg gcaccaacaa caacttgggc atcgccacgc
    30421 tccaccttgc gccattcatc atacttttca ccattggata atcctgagtg aagaatggct
    30481 accttgtccc caaaacgtgc tataaaacgc tcggtcatct gaggagtcaa ggaaatctca
    30541 ggtaccagca aaatagctgt cttgccctta tccagggcac cttggataat ctgcaagtaa
    30601 acctcggtct tcccacttcc tgtaatccct tgaagtagaa agggaggttg agaactgcca
    30661 atagaactca caaccgcatc acgcgcctgt ctttgttctg gatttaactc caaaggtcta
    30721 cttgcttcaa ttccttcaaa ataagcagcc gagcgttgaa cttccttttg gactatggta
    30781 acagcacctt gatccacaaa gaagttgact tgctctcgcg agtaggactc taacaagcta
    30841 gccaaggaag cgctctctgg atgagacagc agataatctc tcagttccaa ctttttcttg
    30901 gcacgtgtag aaatctcaac accttctaat tgagcatggt caacctcata ccaagactgg
    30961 gtcttgacct tcttttgatc gactgcctga tattccagac caagcaggcc ttttctagtc
    31021 aaacgcatca tttcagcttg cttggcaagg tctagtgaag aaaaggctag cgaatcttct
    31081 gaaccaaaca ggcgcactcg ttcttcctga ctcaagcctt ccagaggata gagaatcttg
    31141 tcatagctag aattcagaaa tcctggaagc atggccttga ggatagaaat tttgtaggag
    31201 aagacagatt tgcgtaactc ctcagccagc cagagttgtt ctggcgtgag aacaggagaa
    31261 aaatccagca cctctgcaat atcttttaaa tcttgctcca tctcttctcc atctgattgg
    31321 gactccaaac caagaacaat cccttgaatc aggcgattcc ccttaccaaa aggcacatga
    31381 acccgcatcc caacttccag cattccctca aattcctccg gaatcctgta actatagggc
    31441 tggtccgtct gcatcaaggg cacatctacg ataatcttag ctagggccat cgtctcacct
    31501 cctccttgtc agtacattct tgcaatagaa aaaataagat tgagtccccc caaccttaaa
    31561 ttttttcacc atcttctttt tctttagcaa tttgctcttt gattttcttt tcttcttctt
    31621 ctttgcggcg tttttcttct tcgatacggc gacgcactgc ttcacgtttt ccttctggat
    31681 ctgggtgaat tgtaacgttt cctgattcga tttcttctaa agcgcgaaga gttgattttt
    31741 cagacttaaa accttgagtt gctggggcac ctgcttccaa ttcgtgggca cgttttgctt
    31801 ccaagattac gagtgaatat tttgaaggaa ccttgtcgag caaggtatca atagagggtt
    31861 ttaacatcat ttgcttgtac ctattttcta aattttatcg ggtagttgga gattttggta
    31921 acatctcctg atagtgacca atgacacgat ccacacagaa gtgttctgct tcaatcacac
    31981 atttgacacg ttcagcagct aggggtacct gatcgttgac aatcgcataa tcatactcac
    32041 gcatgagggc aatttcttcc ttggcctttt cgattcgttg ggcaatcact tctgcactat
    32101 ctgttccacg acctaccaag cgatcttgca attcatccaa atctggtggt gtcaggaaga
    32161 taaagacagc atctggaacc tttttcttga cctgaagagc accctgaact tcaatttcaa
    32221 ggaaaacatc gattcccttg tccaaggttt cattgacata ggtcagagga gttccatagt
    32281 agttgccgac atattctgcg tattccaaca tctgtccttg acgaatcagc tcttcaaatt
    32341 cttcacgagt acggaagaaa tagtcaacac cgtccacttc tccaggacgt tgtgcgcgtg
    32401 tcgtcatcga tacagaatat tgaaattggt tttcagaact ctcaaaaatc tctcttctaa
    32461 ccgttccttt tccaacccct gaaggaccag aaaaaacgat tagtaagcct cggtctgcca
    32521 ttgtgtctcc ttttagtcaa tctgtgaaat aacatttctc tagaataatg gcaaaaagcc
    32581 agattatcct ttacagtctt tctatctagt gtaacaaaaa agcagtaatt tttcaactgc
    32641 tctttcttat ttatttagca taatctactg cacgaagctc gcgaatcacg gttaccttga
    32701 tatttcctgg ataatcgaga ttgttttcaa ttttcttacg aactttgtga gccaagattg
    32761 tgactttgtc gtccttgatt tttcctggat tgaccatgat acgaatttca cgtcctgctt
    32821 gaagggcaaa gctagtttgc actccttcaa agccgttagc aatttcttcc aaatcatgga
    32881 gacgcttgat gtagctttca agagactcac tacgagcacc tggacgggct gcgctcaagg
    32941 catctgctgc agcgacgata actgctatca cgctctcagc ttcaacatct ccgtggtgac
    33001 tagcaatcgt attcaccaca actgggggtt ccttgtactt acgggccaat tccataccga
    33061 tttcaacgtg gctaccttca acctcatggt caatggcttt cccgatatcg tgaaggaatc
    33121 cagcacgacg ggcaagagcc gcattttcac caagttcgct cgccatgata ccagccaact
    33181 tagcaacctc aatcgaatgg cgcaaaacat tttgtccata tgaagtacgg aactgcaaac
    33241 gtcccataat cttcatcaag tctggatgaa ggtttggcgc accaatttca taggcagcag
    33301 cctcaccgta ttcacgaatc ttattgtcaa tctcttgacg gtttttctca accaactctt
    33361 cgatacgagc tggatgtata cgaccatctt tgagcaacat ttccatagtc atacgggcaa
    33421 tctcacgacg aatcggatca aatcctgaca aggtcaccac ttctggtgta tcgtcgataa
    33481 tcacatcgac ccctgtcaaa ctttcaaagg tacgaatgtt acgaccttca cgaccaataa
    33541 tgcgtccctt catagtatcg tctggcagat gaactgttga gtttgttgac tccgctacat
    33601 attcaccagc gatacgttgc atagcttgaa ccaagatgtc cttggccatt ttgtcagaac
    33661 gttccttgac ctcttgctca gcttcgcgaa tgcgactggc aatctccctg gtcaagtttt
    33721 cctctgtctg agccaagata atatctcgtg cttctgcctg agacagagca ccaatacgct
    33781 ctagttctgc ttctttttgt ctttcgactt cctctaattg ctcttcacgc gcatcaaggt
    33841 ttttcgctct atcagaaata ctttgttctt tttgttcaag tgtttgttct ttactcgtca
    33901 aattgtcgtc cttacggtca aggctagtag ctctctctgt caaacgactt tcgatttgtt
    33961 tgagttcttg acgttctgat ttgaattcag cgtccacttc ttcacggtat tttctggctt
    34021 cttctttggc ctccaatagt gcttcttttt taagagactt gctttcacgt ttggcttcat
    34081 taacaagtaa atccgcttca cgctcagctt gtccacgtaa attagttgct tcttgttcag
    34141 catttaaaag catcaactct gcagcttcct gagatgattt catcttagct gagatgctga
    34201 catatccaat gactaaacca atgatgacgg caaaaacagc aatcgcaagc gacatgattt
    34261 ccatgttttt acctcatttt attgttattc cgaatgacat acattctttt acattctacc
    34321 ataaaaaaag aatttaaaca aaccttaaat ggatatcgct aacatccgca ttatcactat
    34381 catagttatc atttacagat ataaagcgaa tacctttttc aggaaatatc ttttgtaagt
    34441 actttcctga ctcgatataa tctctgccga aacgagataa atcttttacc ataatgatag
    34501 aaaactttcc tttattcagg tcatcaatca tattcttaaa atttggtcgc tcaaaattag
    34561 aaccactata tccatcatct acatattcat aggataattc aatagatttc tcttctacct
    34621 ccaaaaagca aaaaggataa atttccccta cactttaata gtgaaaattt atccctcttg
    34681 gtaagctctt ttat
//
LOCUS       DAVLAQ010000020        34558 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000020 DAVLAQ010000000
VERSION     DAVLAQ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34558
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.020"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            656..877
                     /locus_tag="VXB71_000955"
     CDS             656..877
                     /locus_tag="VXB71_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451086.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1394..1647
                     /locus_tag="VXB71_000956"
                     /pseudo
     CDS             1394..1647
                     /locus_tag="VXB71_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1775..3004
                     /locus_tag="VXB71_000957"
     CDS             1775..3004
                     /locus_tag="VXB71_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0451087.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3024..5720
                     /gene="ppc"
                     /locus_tag="VXB71_000958"
     CDS             3024..5720
                     /gene="ppc"
                     /locus_tag="VXB71_000958"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0451088.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5803..6020
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6133..7137
                     /locus_tag="VXB71_000959"
     CDS             6133..7137
                     /locus_tag="VXB71_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0451089.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7206..8072
                     /locus_tag="VXB71_000960"
     CDS             7206..8072
                     /locus_tag="VXB71_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451090.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8069..8827
                     /locus_tag="VXB71_000961"
     CDS             8069..8827
                     /locus_tag="VXB71_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451091.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8917..10677
                     /gene="dnaG"
                     /locus_tag="VXB71_000962"
     CDS             8917..10677
                     /gene="dnaG"
                     /locus_tag="VXB71_000962"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0451092.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10680..11789
                     /gene="rpoD"
                     /locus_tag="VXB71_000963"
     CDS             10680..11789
                     /gene="rpoD"
                     /locus_tag="VXB71_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0451093.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11803..12132
                     /locus_tag="VXB71_000964"
     CDS             11803..12132
                     /locus_tag="VXB71_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0451094.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12247..13290
                     /gene="cpoA"
                     /locus_tag="VXB71_000965"
     CDS             12247..13290
                     /gene="cpoA"
                     /locus_tag="VXB71_000965"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0451095.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13306..14631
                     /locus_tag="VXB71_000966"
     CDS             13306..14631
                     /locus_tag="VXB71_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0451096.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14662..14838
                     /locus_tag="VXB71_000967"
     CDS             14662..14838
                     /locus_tag="VXB71_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0451097.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14897..15031
                     /locus_tag="VXB71_000968"
     CDS             14897..15031
                     /locus_tag="VXB71_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0451098.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15095..16405
                     /gene="obgE"
                     /locus_tag="VXB71_000969"
     CDS             15095..16405
                     /gene="obgE"
                     /locus_tag="VXB71_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0451099.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16415..16573
                     /locus_tag="VXB71_000970"
     CDS             16415..16573
                     /locus_tag="VXB71_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451100.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17660..18919
                     /locus_tag="VXB71_000971"
     CDS             17660..18919
                     /locus_tag="VXB71_000971"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0451101.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18935..19486
                     /locus_tag="VXB71_000972"
     CDS             18935..19486
                     /locus_tag="VXB71_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451102.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            19479..20756
                     /locus_tag="VXB71_000973"
     CDS             19479..20756
                     /locus_tag="VXB71_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0451103.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20772..21632
                     /locus_tag="VXB71_000974"
     CDS             20772..21632
                     /locus_tag="VXB71_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0451104.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            22013..22815
                     /locus_tag="VXB71_000975"
                     /pseudo
     CDS             22013..22815
                     /locus_tag="VXB71_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23006..25297
                     /gene="pcrA"
                     /locus_tag="VXB71_000976"
     CDS             23006..25297
                     /gene="pcrA"
                     /locus_tag="VXB71_000976"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0451105.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNVQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            25340..26020
                     /gene="radC"
                     /locus_tag="VXB71_000977"
     CDS             25340..26020
                     /gene="radC"
                     /locus_tag="VXB71_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0451106.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(26017..26706)
                     /locus_tag="VXB71_000978"
     CDS             complement(26017..26706)
                     /locus_tag="VXB71_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0451107.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26724..27365)
                     /locus_tag="VXB71_000979"
     CDS             complement(26724..27365)
                     /locus_tag="VXB71_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0451108.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(27448..27663)
                     /locus_tag="VXB71_000980"
     CDS             complement(27448..27663)
                     /locus_tag="VXB71_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0451109.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(27671..28018)
                     /locus_tag="VXB71_000981"
     CDS             complement(27671..28018)
                     /locus_tag="VXB71_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0451110.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(28023..29138)
                     /locus_tag="VXB71_000982"
     CDS             complement(28023..29138)
                     /locus_tag="VXB71_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0451111.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(29148..30107)
                     /locus_tag="VXB71_000983"
     CDS             complement(29148..30107)
                     /locus_tag="VXB71_000983"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0451112.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(30220..30789)
                     /locus_tag="VXB71_000984"
     CDS             complement(30220..30789)
                     /locus_tag="VXB71_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0451113.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            30917..31588
                     /locus_tag="VXB71_000985"
     CDS             30917..31588
                     /locus_tag="VXB71_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0451114.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            31572..32390
                     /locus_tag="VXB71_000986"
     CDS             31572..32390
                     /locus_tag="VXB71_000986"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0451115.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            32387..33283
                     /locus_tag="VXB71_000987"
     CDS             32387..33283
                     /locus_tag="VXB71_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0451116.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            33327..34301
                     /gene="pta"
                     /locus_tag="VXB71_000988"
     CDS             33327..34301
                     /gene="pta"
                     /locus_tag="VXB71_000988"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0451117.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT        10444 a         6165 c         7594 g        10355 t
ORIGIN      
        1 attcagtcaa ctacaaactt aggtattaaa ttattagttt gtatctggat tatgggattt
       61 gaatttttcc ttcttccaaa actaataaaa ttgaaagaac aaaatctagt ttaaatgttg
      121 ctcgaaaatt aaataattga atacgattaa caatgaaaca atacaacgtg agtcatgact
      181 tcaaagtaat tgattttatg attctggttt cttacgctta attaagcaag ttgtattcac
      241 tttatcaaat tgttattact ctaaaaagcg tctaacagct atagagtgtc tgtttgcttc
      301 tctttacttt tattttaaat aattcattaa ccttccgtaa gtgcccaata ataaggtgtg
      361 ttgaagaagt ctgagataaa atagttctca gtcacaaaaa agctatagat tcccattggt
      421 gaacagctcc ctgtcaagta gacagtaaaa taatataaaa tcttaagcga cctgattcct
      481 gaattccagt ggagtcaggt tgttttttaa ccgtctttct taatattgtc ttacctataa
      541 tagatatgct tatgagatat gtttaataaa ttaattttag ttcaaaatgt ccagttagga
      601 cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa gctagatgta
      661 cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa tagctaaaat
      721 actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata cgttaacagc
      781 agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc tattggaatt
      841 gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc atagagtgtg
      901 aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat ggtactttcc
      961 tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa aaccatcaat
     1021 aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata cttctgaccg
     1081 ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt catcagtcat
     1141 gccacgttaa atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa ggttccccga
     1201 accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct aaaagcgtaa
     1261 aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa tacaataaaa
     1321 ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc cttgtaggtg
     1381 ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg taaacgcgca
     1441 aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac tattcaatac
     1501 atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca cgaaagcaac
     1561 ttaatccgtc ggagccaatg ggttgaagta actcttgttc aaaatggttt tacgatttca
     1621 aattctgccc taattatgaa aaacagtaaa attcgaagga ttgtaaggta agagtttttt
     1681 tctttctgaa aaaatggtat aatagcaatc aaaactagaa aataaaacgg aatttggaac
     1741 agatttgtct gtatcctagt agagtggtga tgctatgaag attagtaaga ggcacttatt
     1801 aaattattcc atcttgattc cctacttgct tttatctatt ttgggcttga ttgtggtcta
     1861 ttcgaccacc agtgctattt taattgaaga aggcaagagc gccttgcagt tggttcgaaa
     1921 ccaaggaatc ttttggattg ttagtttgat actgattgcc ttaatttata aattgagact
     1981 agattttttg agaaatgagc gactaatcat tttagttata ttaatagaaa tgcttttatt
     2041 gttcttggct cgttttattg gtatttccgt aaacggggca tacggttgga tttcggttgc
     2101 aggagtaact attcagccag ctgagtactt aaaaatcatt attatttggt atttagctca
     2161 ccgattctcc aaacagcaag aagaaatagc tacttatgat tttcaagttt tgactcaaaa
     2221 tcaatggctt ccccgtgctt ttaatgattg gcgattcgtt ctcctagttc tgattggaag
     2281 tttgggaatt ttccctgatt taggaaatgc gactatttta gtcttggttt ccttgattat
     2341 gtatacagtt agtggaatcg cttatcgctg gttttcaacc attctggcgc tcgtatctgc
     2401 cgcttctgtc tttgtcttga ccactatcag cctaatcggt gttgagacct tttcaaaaat
     2461 tccagtattt ggctatgtag ccaagcgctt tagtgccttt tttaatcctt ttgccgatcg
     2521 tgctgatgca ggtcaccagt tagctaattc ttattttgcc atggtcaatg gtggttggtt
     2581 tggtctaggt cttggaaact cgattgaaaa acgaggttat ttgccagaag ctcatacaga
     2641 ctttgtcttt tctatcgtga ttgaagaatt tggctttgct ggtgccagtc ttattttagc
     2701 tctcttgttt ttcatgattt tgcggattat cttggtcggt attcgagcgg agaatccttt
     2761 caatgccatg gttgcactcg gtgtcggagg gatgatgttg gttcaggtat ttgtcaatat
     2821 cggagggatt tcgggcttga ttccatctac aggagtaacc ttccccttct tatcccaggg
     2881 tggaaatagt cttctagtct tatcagtggc agtagccttt gtcttaaata ttgatgccag
     2941 tgaaaaacgc gctaagttgt accgagaatt ggaaaatcaa ccaatgaacc ttctgttgaa
     3001 gtaggataaa gaaaggatag tttatgtctc ttcaaaaatt agaaaattat agtaataaaa
     3061 gtgttgtgca agaagaagtc ttgattctaa cagaattact ggaagatatt actaaaaata
     3121 tgcttgcccc agagaccttt gaaaaaataa tacagttgaa agaattatca acgcaggaag
     3181 attatcaagg tctaaaccgt ctagtgacta gcttatcaaa tgatgaaatg gtctatattt
     3241 cacgctattt ctctatctta cctcttttga tcaatatttc agaggatgtg gatttagctt
     3301 atgaaatcaa tcatcaaaat aatattgatc aggactattt aggtaaatta tctacaacga
     3361 ttaaattggt agcagaaaag gaaaatgccg ttgagatcct agaacacttg aatgttgtcc
     3421 ctgttttgac agcccatcca acacaagtgc aacgcaaaag tatgttggat ttaacaaatc
     3481 atattcatag tcttttgcgt aaataccgtg atgttaagtt ggggttgatc aataaagata
     3541 aatggtacaa tgatttgcgt cgttacatcg aaattatcat gcagacagac atgattcgtg
     3601 agaaaaaatt aaaagtgact aacgaaatca cgaatgctat ggaatattat aacagctcct
     3661 ttttgaaagc tgtacctcat ttgacgacgg agtataagcg cttagcgcaa gcgcatggtc
     3721 tgaatttaaa acaggctaaa ccaatcacca tgggtatgtg gataggtggt gaccgtgatg
     3781 gaaatccatt tgttacagca gagaccttga agcagtctgc actcactcaa tgtgaagtca
     3841 tcatgaacta ctatgataaa aagatttacc aactttatcg tgaattttct ctttcaacta
     3901 gcattgtcaa cgtcagcaag caagtcagag aaatggctcg tcaatccaag gataactcga
     3961 tttaccgcga aaaagagctt taccgtcgtg ccttgtttga tattcaatca aaaattcagg
     4021 caactaaaac ctatctgatt gaggatgaag aagttgggac tcgttatgaa accgccaatg
     4081 atttctacaa ggatttgatt gccattcgag attctctact agaaaataag ggtgagtcct
     4141 tgatttcagg tgattttgtg gaattattgc aggcagtaga gatatttggt ttttacctag
     4201 catcaattga tatgcgacaa gactctagcg tctatgaagc ctgtgtggca gaactcttga
     4261 aatcagcagg aattcattct cgttatagcg agttgagcga agaagaaaag tgtgaccttc
     4321 tcttgaaaga attagaagaa gatccccgaa ttctttctgc gactcacgca gaaaaatcag
     4381 aattattagc aaaagaatta gctattttta agacggctcg tgttttgaaa gataagttgg
     4441 gagatgatgt catccgtcag accatcattt cacatgcaac cagcctttct gatatgctag
     4501 aattagctat tctgttaaaa gaagtaggac tggtggatac ggaaagggcg cgtgttcaga
     4561 ttgttcccct ttttgaaaca attgaagact tggatcattc agaagaaaca atgagaaaat
     4621 atctttctct tagccttgcc aaaaaatgga ttgactcacg aaataactac caagaaatca
     4681 tgcttggcta ctctgacagt aataaagatg gcggttactt gtcatcatgt tggaccctct
     4741 acaaggctca acaacaattg actgctattg gagatgaatt tggcgttaag gttaccttct
     4801 tccatggtcg tggtggtact gtcggtcgtg gtggtgggcc aacctatgaa gccattacat
     4861 ctcaaccgct caagtctatc aaggatcgta tccgcttgac ggagcagggt gaagtaattg
     4921 ggaataaata cggtaacaaa gacgccgctt actataacct tgaaatgcta gtatcggcag
     4981 ctattaaccg tatgattact cagaagaaga gcgataccaa taccccaaat cgttatgaag
     5041 ccattatgga tcaagtagtg gaccgtagtt acgatatcta ccgtgatttg gtctttggta
     5101 atgagcattt ctatgattat ttcttcgagt caagtccaat caaggctatt tcaagtttta
     5161 atattggttc tcgtccagcc gctcgtaaga ctattactga aatcggtggt ttgcgtgcca
     5221 tcccttgggt attctcatgg tcacagagtc gtgttatgtt ccctggatgg tacggggttg
     5281 gttcaagctt caaggaattt atcaataaaa atccagagaa tattgctatc ttacgagata
     5341 tgtaccaaaa ttggcctttc ttccaatcgc ttctttcaaa tgttgatatg gttttgtcaa
     5401 aatcaaatat gaatattgct tttgaatatg ctaaactttg tgaagacgag caagttaagg
     5461 ccatctatga gactatttta aatgaatggc aagttactaa gaacgttatc ttggctattg
     5521 aaggacatga cgaactctta gctgacaatc catatctaaa agctagtctg gattaccgta
     5581 tgccttactt taatattctc aactatattc agttagagtt gattaaacgc caacgtcgtg
     5641 gagaattgtc cagtgatcaa gaacgattga ttcatatcac catcaacgga attgcgacag
     5701 gattgcgtaa ttcaggttga taattttcaa gagtgaatgc taaaagtgaa tatcaaaaaa
     5761 attctaatag actattgaca agtagtttaa aaatgatata atttaaccat tcagaaaagt
     5821 aatcatacaa actttttaga gagtctgtgg tagctgaaaa cagataagtg gcgatgatga
     5881 aaattgggct gaatgctatt tagaatttga aattataaaa attcggtaag cacaccttac
     5941 agtgcatctc gttattgcga gactgagcga tagggaaatt ccctataatt gaggtggtac
     6001 cgcgcatcga cgtcctcaca caagtttttt gtgtgaggat ttttttgatg gaggttagta
     6061 tggaaagaaa acgatggcgt cgcttgttta gataagtgaa atatgttaaa ggaaataaaa
     6121 aggagaaaca gaatgaaaaa taaacgttta attggaatta ttgctgcatt agcagtctta
     6181 gtagcaggaa gcttgattta ttcttcaatg aataaatcag aagctcagaa taataaggat
     6241 gagaagaaaa taactaagat tggtgtgctt caatttgtga gccatccatc ccttgatttg
     6301 atttataaag ggatccaaga tggacttgca gaagaaggat ataaagatga tcaagttaaa
     6361 attgatttta tgaactcaga aggtgaccaa agtaaggttg cgacaatgag taaacaattg
     6421 gttgcaaatg ggaatgacct tgtggttggt atcgcaacac cagcagccca agggttggct
     6481 agtgcaacaa aagacctacc ggttatcatg gccgctatta cagacccaat tggtgctaac
     6541 ttggttaaag atttgaaaaa accaggtggc aacattacag gggtatctga ccacaatcca
     6601 gctcaacaac aagttgaact catcaaggct ctgacaccga atgtgaaaac aatcggagct
     6661 ctttactcaa gtagcgaaga caattcaaaa acacaggtcg aagaatttaa ggcttatgct
     6721 gaaaaagcag gtctgacagt ggaaacattt gcagttcctt caacaaatga aattgcctca
     6781 actgtcactg ttatgactag caaggtagat gctatttggg ttccaattga taacaccatt
     6841 gcatcaggat ttccaacggt tgtctctagc aatcaaagtt ctaagaaacc aatttatccc
     6901 agtgcgacag ctatggtaga agtaggtggt ttggcatcag ttgtaattga ccaacatgac
     6961 cttggtgtgg caacaggtaa aatgattgtg caagtcttga aaggtgcaaa accagccgat
     7021 accccagtca atgtcttttc aactggtaag tcagtcatca ataaaaaaat agcacaagaa
     7081 ctaggtatta ctattcctga gtctgttctc aaagaagcag gacaagtcat cgaataaata
     7141 aggtagggag gaggagactc ttcccatttt ttaaaaagat gaatatagaa aggattaaat
     7201 aaaatatgat tgtttccatt atttctcaag gatttgtctg ggctattcta ggtctgggaa
     7261 tctttatgac atttaggatt ttaaactttc cagatatgac gacagaaggt tccttccctc
     7321 ttgggggagc tgttgctgtc actttgataa ccaaaggcgt gaacccattt ttagcgacac
     7381 ttgttgctgt aggagcaggt tgtttggctg gaatggcagc aggccttctt tatacaaaag
     7441 ggaagatccc aaccttgcta tcagggattt tggtgatgac ttcttgtcac tcaatcatgc
     7501 tcttgattat gggacgtgcg aatttaggcc tgcttggaac caagcaaatt caggatgttt
     7561 tgccttttga ttcggatttg aatcaactct tgacaggtct catctttgtg agtattgtta
     7621 ttgctctcat gctctttttc ttggacacta aactcggaca agcctatatt gctacagggg
     7681 ataatcctga tatggctaga agtttcggga ttcatactgg acgcatggag ctcatgggct
     7741 tggtcttatc aaatggtgtg attgcccttg caggtgccct cattgctcag caagaaggtt
     7801 atgccgatgt gtctcgaggg atcggggtta tcgttgtggg gcttgcaagt ttgattattg
     7861 gagaagttat tttcaagagt ttgagcttgg cagagcgttt ggttactatc gttgtaggtt
     7921 ctatcgctta tcaattttta gtgtgggcag ttatcgcact tggctttaat acaagttacc
     7981 ttcgtttata cagtgccttg attttagcag tctgcctcat gattccaaca tttaagcaaa
     8041 caatcttgaa aggagccaag ttaagcaaat gacagcaatt gtagaattaa aaaatgcaac
     8101 caaaatcgtt aaaaatggct ttgatgaaga aaagattatt ttaaatgatg tttccttaga
     8161 aatttttgaa cgggacttta tcacgatttt gggcggaaat ggtgctggaa aatcaaccct
     8221 ctttaacact atagcaggga ccttatcact aactagtgga actatccgta ttttaggtga
     8281 agaactcact aagttttcac ccgagaagcg tgccaagtac ctgtctcgtg tcttccaaga
     8341 tccaaagatg gggacagctc cccgtatgac ggtcgctgaa aatcttttaa tcgccaagtt
     8401 tcgtggtgaa aagcgtggat tgttaccacg acgcttgact agctataagg atgaatttca
     8461 ggcaaccatt gaaaaagtag gaaatggtct tgagaaacac ttgaatacac cgattgagtt
     8521 cttatcaggt ggacaaagac aggctttgag tctcttgatg gcaaccttga agcgacctga
     8581 attactcctg ttagatgagc atactgctgc cctggatcca aagactagtg ttgctttgat
     8641 ggaattgaca gatgaatttg ttaagaaaga tcagctaaca gcccttatga ttactcatca
     8701 tatggaagat gctctcaaat acggcaatcg cttgattgtc atgaaagaag gacggattat
     8761 ccaagattta aaccaagaag aaaaagcaaa aatgaaaatc tctgattatt atcaactctt
     8821 tgaataaagt agggaaaatg agtgaaatgg tttacttttt ttctgaaata aagtatacta
     8881 tataaagtaa actatgataa catggaggta ttgtgtatgg ttgacaaaca agtcattgaa
     8941 gaaatcaaaa acaatgccaa cattgtggaa gtcataggag atgtgatttc tttacaaaag
     9001 gcaggacgga actatctagg gctctgtcct tttcatggtg aaaaaacacc ttctttcaac
     9061 gttgtagagg ataagcagtt ttatcactgt ttcggttgtg gtcgctcagg tgatgtcttt
     9121 aagttcatcg aggagtacca aggggttccc tttatagagg cagtccaaat cttaggtcag
     9181 cgtgttggaa ttgaggttga aaaaccgctt tatagtgagc agaagccagc ctcacctcac
     9241 caagctcttt atgatatgca cgaagatgca gccaaatttt accatgcgat tctcatgaca
     9301 acgactatgg gcgaagaggc cagaaattac ctttatcagc ggggtttgac agatgaagtg
     9361 cttaaacatt tttggattgg tttagcacct ccagaacgaa actatctcta tcaacgtttg
     9421 tctgatcagt atcgtgaaga ggatttactg gattcaggcc tgttttatct ctcggatgcc
     9481 aatcaatttg tagacacctt tcacaatcgc attatgtttc ccctgacaaa tgaccaagga
     9541 aaggtcattg ccttctcagg tcgtatctgg caaaaaacgg attcacaaac ttctaagtat
     9601 aaaaacagcc gatcgactgc aatttttaac aaaagttacg aattatatca tatggatagg
     9661 gcaaaaaaat cttctggaaa agctagtgag atttacttga tggaaggatt catggatgtt
     9721 attgcagcct atcgggctgg aatcgaaagt gctgtggcgt cgatgggaac ggccttgagt
     9781 cgagagcatg ttgagcatct gaaaaggtta accaagaaat tggttcttgt ttacgatgga
     9841 gataaggctg ggcaagccgc gacattgaaa gcattggatg aaattggtga tatgcctgtg
     9901 caaatcgtca gcatgcctga taacttggat cctgatgagt atctacaaaa aaatggtcca
     9961 gaagacttgg cctatctatt aacgaaaact cgtattagtc cgattgagtt ctacattcat
    10021 cagtacaaac ctgaaaacag tgaaaatctg caggctcaga ttgagtttct tgaaaaaata
    10081 gctcccttga ttgttcaaga aaagtccatc gctgctcaaa acagctatat tcatatttta
    10141 gctgacagtc tggcgtcctt tgattatacc cagattgagc agattgttaa tgagagtcgt
    10201 caggtgcaaa ggcagaatcg catggaagga atttccagac cgacgccaat caccatgcca
    10261 atcaccaagc agttatcggc tattatgagg gcagaagccc atctactcta tcggatgatg
    10321 gaatcccctc ttgttttgaa cgattaccgt ttgcgagaag actttgcatt tgctacacct
    10381 gaatttcagg tcttatatga cttgcttggc cagtatggaa atcttcctcc agaagtttta
    10441 gcagagcaga cagaggaagt tgaaagagct tggtaccaag ttttagctca ggatttgcct
    10501 gctgaaatat cgccgcagga acttagtgaa gtagagatga ctcgaaacaa ggctctcttg
    10561 aatcaggaca atatgagaat caaaaagaag gtgcaggaag ctagccatgt aggagataca
    10621 gatacagccc tagaagaatt ggaacgttta atttcccaaa agagaagaat ggagtaataa
    10681 tggcaacaaa acaaaaagaa gtaacaacat ttgacgtaca ggtagcagaa tttatccgta
    10741 atcataagca aaaagggaca gcaacagatg atgaaatcaa tgcaagtctg gttattcctt
    10801 ttaccttgga cgctgatggg attgaagatc tcttgcaacg gattcaggat gcaggaattt
    10861 ctatcacaga taacgaagga aatccaagtg cgcgtgttct tagcaatgaa gaagaaccag
    10921 aactcagcga tgaggacttg attgggtcaa cttctgctaa ggtcaatgac cctgtccgta
    10981 tgtacttgaa agaaataggg gtcgttcctc tcttgaccaa tgaagaggag aaagagttgg
    11041 cactggctgt tgaagctggt gatatcgaag ccaaacaacg tcttgcggaa gccaatcttc
    11101 gtttggttgt ttccattgcc aaacgctatg tcggtcgtgg catgcagttc cttgacttga
    11161 ttcaagaagg aaatatgggc ttgatgaagg cggttgacaa gtttgactat tctaaagggt
    11221 tcaagttttc aacttatgca acttggtgga ttcgtcaggc tatcactcgt gctattgcgg
    11281 accaagctcg taccatccgt atcccagttc acatggttga aactatcaat aaattggttc
    11341 gtgaacagcg gaatctcctt caagaattgg ggcaagatcc gacaccagaa cagattgctg
    11401 aacgaatgga tatgacacct gataaggttc gtgaaatctt gaagattgcc caagaaccag
    11461 tatctcttga aactcctatc ggtgaagagg acgatagcca ccttggagac tttatcgaag
    11521 atgaagtgat tgaaaatcca gtggattata cgactcgtat cgtcttgcgt gagcaattgg
    11581 atgaaatctt agatactctt acagaccgtg aagaaaatgt tctgcgtcta cgttttggac
    11641 tagatgatgg aaaaatgcgc acacttgaag atgtggggaa agtctttaac gtaactcgtg
    11701 agcgtatccg tcagattgaa gcaaaggctt tgagaaaact acgccaacca agtcgtagca
    11761 aaccgcttcg tgattttatt gaagactaag agtgaggaaa atatggctta tacagaagag
    11821 caaattgaaa acatcaaaac acggatttta acagccttgg aagaagtcat cgaccctgag
    11881 ttgggaatcg atattgtcaa tcttggtttg atctatgaga ttcgttttga cggtgacaca
    11941 gggcaaacag agattgacat gactttgaca actatgggtt gtcccttagc agaccttttg
    12001 acagaccaga tttatgatgc tatgatagag gttccagaag taacggatac tgaggttaaa
    12061 ttagtctggt atccagcctg gacagttgaa aaaatgagtc gctatgcccg cattgcccta
    12121 ggcattaagt aaacatataa aagcatgtga gagactgttg gaaaagcgag gaaatttccc
    12181 ctcttttcct ctagtctctc ctttcttttg ctgattttat tcaaagaaaa tgatataata
    12241 gtagttatgg agaaaaagaa attacgcatc aatatgttga gttcaagtga gaaagtagca
    12301 ggacagggag tttcaggtgc ttaccgtgaa ttagttcgtc ttcttcaccg tgctgccaag
    12361 gaccaattga ttgttacaga aaatcttcca atcgaggcag atgtgactca ctttcatacg
    12421 attgattttc cctattattt atcaaccttc caaaagaaac gctcagggag aaagattggc
    12481 tatgtgcatt tcttgccagc tacacttgag ggaagtttga aaattccatt tttcttaaag
    12541 ggaattgtga aacgctatgt attttctttt tacaaccgga tggagcactt ggttgtggtc
    12601 aatcctatgt ttattgagga tttggtagca gctggtattc cacgtgaaaa agtgacctat
    12661 attcctaact ttgtcaacaa ggaaaaatgg catcctctac cacaagaaga ggtagtcaga
    12721 ctgcgcacag atcttggtct tagtgacaat cagtttatcg tagtaggtgc tgggcaagtt
    12781 cagaaacgta aagggattga tgactttatc cgtctggctg aggaattgcc tcagattacc
    12841 tttatctggg ctggtggctt ctcttttggt ggtatgacag atggttatga acactataag
    12901 aaaattatgg aaaatccccc taaaaatttg atttttccag gcattgtatc gccagagcgg
    12961 atgcgcgaat tgtatgctct agcggatctt ttcttgttgc ctagttacaa tgagctcttt
    13021 cctatgacta ttttagaagc tgcgagttgt gaggctccta ttatgttgcg tgatttagat
    13081 ctctataagg taattttgga gggaaattat cgggcgacag cgggtagaga agagatgaaa
    13141 gaggctattt tggaatatca agcaaatcct gctgccttaa aagatctcaa agaaaaggct
    13201 aagaatattt ccagagagta ttctgaagag catctgttac aaatctggtt ggacttttat
    13261 gagaaacaag ccgctttagg gagaaagtaa aaagtgaggt aatctatgcg aattggttta
    13321 tttacagata cctattttcc tcaggtttct ggtgttgcga ccagtattcg aaccttgaaa
    13381 acagaacttg aaaagcaggg acatgctgtt tttatcttta cgacgacaga taaggatgtc
    13441 aatcgctacg aagattggca aattatccgc attccaagtg ttcctttctt tgcttttaag
    13501 gatcgtcgct ttgcctaccg aggttttagc aaggcacttg aaattgctaa acagtatcag
    13561 ctagatatta tccatactca gacagaattt tctcttggcc tgttggggat ttggattgcg
    13621 cgtgaattga aaattccagt catccatacc tatcacaccc agtatgaaga ctatgtccat
    13681 tatattgcta aggggatgtt gatccggccg agtatggtca agtatctggt tagaggtttc
    13741 ctgcatgatg tggatggggt tatttgtcct agtgagattg tccgtgactt gctatctgat
    13801 tataaggtca aggttgaaaa acgggtcatt cctactggga ttgaattagc caagtttgag
    13861 cgtccggaaa tcaagcagga aaatttgaaa gaactgcgta gtaaactagg gattcaagat
    13921 ggtgaaaaga cgttgcttag tctttcgaga atctcctatg aaaaaaatat tcaagcagtt
    13981 ttagcagcct ttgctgatgt tctgaaagag gaagacaagg ttaaactggt agtagctggg
    14041 gatggccctt atctgaatga cctcaaagag caagctcaga acctagagat tcaagactca
    14101 gtcatcttta cagggatgat tgctcctagt gagacggctc tttactataa agcggcggat
    14161 ttcttcattt cggcatcgac aagcgaaacg caaggtttga cctacttgga aagcttagcc
    14221 agtggaacac ctgtcattgc tcacggaaat ccttatttga acaacctcat cagtgataaa
    14281 atgtttggaa ccttgtacta tggagaacat gatttggctg gtgctatttt ggaagccctg
    14341 attgcaacac cagacatgaa cgagcatacc ttatcagaga aattgtatga gatttcagct
    14401 gagaactttg ggaaacgagt gcatgagttt tatctggatg ccattatttc aaataacttc
    14461 cagaaagatt tggctaaaga tgatacggtc agtcagcgta tctttaagac agttttgtat
    14521 cttcagcaac aggtggttgc tgtacctgta aaaggatcta gacgcatgtt gaaggcttca
    14581 aaaacacagt tgatcagtat gagagactat tggaaagacc atgaagaata gaaagaggaa
    14641 cagctatgaa aaaaacaatt aatgagaagc ggtcgtgata aaaagattgc gggtgtttgt
    14701 gctggggtgg cccattatct ggatatggat ccgactatcg ttcaagtcat ttggggtgtt
    14761 cttacttgct gttacggagc tggaattgta gcttacatta ttttatggat tatcgcacca
    14821 gtagcaactg actattgaaa actagctcaa ttcatgctaa gataatagaa aatagaatgt
    14881 aacgaaggag agaaaaatgg catttggaga taatggaaat cgtaaaaaaa ctatgtttga
    14941 gaaaataacc ttgtttatcg tgattatcat gctagtagca agtttattgg gaatttttgc
    15001 aactgcaatt ggtgccctca gtaatctata aaatagattc aagaaaattt agtgactggg
    15061 atttcccagc ccttttttaa agtgagaaga aataatgagt atgtttttag atacagctaa
    15121 gattaaggtc aaggctggta atggtggcga tggtatggtt gcctttcgtc gtgaaaaata
    15181 tgtccctaat ggaggccctt ggggtggtga tggtggtcgt ggaggcaatg tggtcttcgt
    15241 tgtagacgaa ggactacgta ccttgatgga tttccgctac aatcgtcatt tcaaggctga
    15301 ttctggtgaa aaagggatga ccaaagggat gcatggtcgt ggtgctgagg accttagagt
    15361 tcgagtacca caaggtacga ctgttcgtga tgcggagact ggcaaggttt taacagattt
    15421 gattgaacat gggcaagaat ttatcgttgc ccacggtggt cgtggtggac gtggaaatat
    15481 tcgtttcgcg acaccaaaaa atcctgcacc ggaaatctct gaaaatggag aaccaggtca
    15541 ggaacgtgag ttacaattgg aactaaaaat cttggcagat gtcggtttag taggattccc
    15601 atctgtaggg aagtcaacac ttttaagtgt tattacctca gctaagccta aaattggtgc
    15661 ctaccacttt accactattg taccaaattt aggtatggtt cgcacccaat caggtgaatc
    15721 ctttgcagta gccgacttgc caggtttgat tgaaggggct agtcaaggtg ttggtttggg
    15781 aactcagttc ctccgtcaca tcgagcgtac acgtgttatc cttcacatca ttgatatgtc
    15841 agctagcgaa ggccgtgatc catatgagga ttacctagct atcaataaag agctggagtc
    15901 ttacaatctt cgcctcatgg agcgtccaca gattattgta gctaataaga tggacatgcc
    15961 tgagagtcag gaaaatcttg aagaatttaa gaaaaaattg tctgaaaatt atgatgaatt
    16021 tgaagagtta ccagctatct tcccaatttc tggattgacc aagcaaggtc tggcaacact
    16081 tttagatgct acagctgaat tgttagacaa gacaccagaa tttttgctct acgacgagtc
    16141 cgatatggaa gaagaagctt actatggatt tgacgaagaa gaaaaagcct ttgaaattag
    16201 tcgtgatgac gatgcgacat gggtactttc tggtgaaaaa ctcatgaaac tctttaatat
    16261 gaccaacttt gatcgtgatg aatctgtcat gaaatttgcc cgtcagcttc gtggtatggg
    16321 ggttgatgaa gcccttcgtg cgcgtggagc taaagatggg gatttggtcc gcattggtaa
    16381 atttgagttt gaatttgtag actaggagac tggtatggga gataaaccga tatctttccg
    16441 agatgcggat ggtaattttg tttccgccgc agacgtttgg aatgaaaaga aattggaaga
    16501 actatttaat cgtctcaatc caaatcgtgc cttgagattg gcacgaacta aaaaggaaaa
    16561 tccatctcag taaagaagct aaaaaatccc gtgcctcatc agacacggga ttttgtggta
    16621 cgacaggcat gtatagcaaa ctgaatctgg aatagcacag catatcttct aaaatattgc
    16681 tataaattga tttgaatttc aaaattaaat tgttttattc ttatttcaat ttgttatagt
    16741 atatctgatg tcaaagttct cggcgagtca aatagtgatt cccaagcctg actatcgtga
    16801 ggtagcggat taaaatggtc tggggataga ccgttttaag tctgatgctg gaaataagaa
    16861 ttgtcagaag aagggatagc gaaatcgtgg ctctacgaac aggaacgtga taataaggcg
    16921 tatatagcga ataagagggc ctcaaactct aaagtccaaa aaggtagtcg taacctatat
    16981 gcgtaaatca tgagagtaat tgaattcgta ctaagatttt ctatttttac tgtaaccttt
    17041 taacgtcctc atatcttgta tacacgagga aagatgtacg acttatcccg tgaggtctat
    17101 cactataaag agaaaacgac agatagaagt gatcctgagt cacggttatc tttaaaatag
    17161 attgtctgat aggatgctag cctgaaaacg tcttgttcat gaaatatagg acggtatgta
    17221 taaaacgctt ctgtgaactg agagaagggg gagaagttct tgctaaaatt tagttgaaca
    17281 gccgtattcc gatacttaga taagagatct agtcttagct cctactcagt ttcaggggat
    17341 aaaaaagggg caatagcgat tcgagaaaga ttatactctt cgaaaatctc ttcaaatcac
    17401 gtcaatatcg ccttgccgta tgtgtaggat actaactacg tcagttccat ctacaatctc
    17461 aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgatctttga tttttattga
    17521 gtattagtaa ttcagttact aactcgtcaa ctctgattta tccaataaaa ttgaaaagga
    17581 tggaaaaaag gataaattta tgatatactt tattttgaag accttattag aaatcttgaa
    17641 agagtattga aaacttagaa tgagaaaaat tgttatcaat ggtggattac cactgcaagg
    17701 tgaaattact attagtggtg ctaaaaatag tgttgtggcc ttaattccag ctattatatt
    17761 ggctgatgat gtggtgactt tggattgtgt tccagatatt tcggatgtag ccagtcttgt
    17821 cgaaatcatg gaattaatgg gagctactgt taagcgttat gacgatgtct tggagattga
    17881 tccaagaggt gttcaaaata ttccaatgcc ttatggtaaa attaacagtc ttcgtgcatc
    17941 ttactatttt tatgggagcc tcttaggccg ttttggtgaa gcgacagttg gtctaccggg
    18001 aggatgtgat cttggtcctc gtccgattga cttacacctt aaggcgtttg aagctatggg
    18061 tgccactgct agctacgagg gagataacat gaagttatct gctaaagata caggacttca
    18121 tggtgcaagt atttacatgg atacggttag tgtgggagca acgattaata cgatgattgc
    18181 tgcggttaaa gcaaatggtc gtactattat tgaaaatgca gcccgtgaac ctgagattat
    18241 tgatgtagct actctcttga ataatatggg tgcccatatc cgtggggcag gaactaatat
    18301 catcattatt gatggtgttg aaagattaca tgggacacgt catcaggtga ttccagaccg
    18361 cattgaagct ggaacatata tatctttagc tgctgcagtt ggtaaaggaa ttcgtataaa
    18421 taatgttctt tacgaacacc tggaagggtt tattgctaag ttggaagaaa tgggagtgag
    18481 aatgactgta tctgaagaca gcatttttgt cgaggaacag tctaatttga aagcaatcaa
    18541 tattaagaca gctccttacc caggctttgc aactgatttg caacaaccgc ttacccctct
    18601 tttactaaga gcgaatggtc gtggtacaat tgtcgatacg atttacgaaa aacgtgtaaa
    18661 tcatgttttt gaactagcaa agatggatgc ggatatttcg acaacaaatg gtcatatttt
    18721 gtacacgggt ggacgtgatt tacgtggggc cagtgttaaa gcgaccgact taagagctgg
    18781 ggctgcacta gtcattgctg ggcttatggc tgaaggtaaa actgaaatta ccaatatcga
    18841 gtttatctta cgtggttatt ctgatattat cgaaaaatta cgtaatttag gagcggatat
    18901 tagacttgtt gaggattaaa ccgtagaggt gtttatgaat atttggacca aattagcaat
    18961 gttttctttt tttgaaacgg atcgcttgta tttgcgtcct ttctttttta gtgatagtca
    19021 ggacttccgc gagatagctt caaatccaga aaatcttcaa tttattttcc caacgcaggc
    19081 aagtctggaa gaaagtcaat atgcactggc caattacttt atgaagtccc ctttgggagt
    19141 gtgggcaatt tgtgaccaga aaaatcaaca aatgattggt tctattaaat ttgagaagtt
    19201 agatgaaatc aaaaaagaag ctgagcttgg ctattttttg agaaaagatg cttggtcgca
    19261 aggatttatg acagaggttg ttagaaaaat ttgtcagctt tcttttgagg aatttggctt
    19321 aaaacaatta tttatcatta cccaccttga aaatgaagct agccaaagag ttgctcttaa
    19381 gtctggattt agtttgttcc gtcagtttaa gggaagtgat cgttacacaa gaaaaatgcg
    19441 ggattatctt gaatttcggt atgtaaaagg agagttcaat gagtaagcat caggaaattc
    19501 taagctattt ggaggaatta ccagtaggta aaagggtcag tgttcgtagc atttcgaatc
    19561 atctaggagt tagtgatgga acagcctatc gagctattaa agaagctgaa aaccgtggaa
    19621 ttgtggagac ccgtcctaga agtggaacaa ttcgtgttaa atcccagaaa gttgctatag
    19681 agagattaac gtttgctgaa attgcagaag tgacttcttc tgaggttctg gctgggcaag
    19741 aaggtttaga gagagagttt agtaagtttt caattggtgc catgactgaa caaaatatct
    19801 tgtcttacct tcatgatggg gggctcttga ttgtcggaga ccgaacccgt attcagttgc
    19861 tagccttgga aaatgaaaat gcagttctgg ttacaggggg atttcaggtt catgatgatg
    19921 tgcttaaact ggccaatcaa aaagggattc ctgttctaag aagtaagcat gataccttta
    19981 ccgtcgcgac catgatcaat aaagccttgt caaatgtcca aatcaagact gatattctga
    20041 cagttgagaa actttatcgc cctagtcatg agtatggttt tctgagagag acagatacag
    20101 ttaaagatta tttggacttg gttcgtaaga atcgtagcag ccgtttccct gttatcaatc
    20161 aacatcaggt cgttgttggt gttgtaacca tgagagacgc tggtgataaa tcaccaagca
    20221 cgacaattga taaggttatg tctcgtagtc tattttgggt tggattatcg acaaatattg
    20281 ccaatgtgag tcaacggatg atcgcagaag actttgaaat ggtaccagtt gttcgaagca
    20341 atcaaacttt gcttggcgtt gtgacgcgac gagatgtcat ggagaagatg agccgttccc
    20401 aagtttcggc tctaccaact ttttctgagc agattggaca aaagctctct tatcaccatg
    20461 atgaagtagt cattacagtg gaacccttta tgctagaaaa aaatggagtt ttggctaatg
    20521 gtgtattggc agaaattctg acccacatga cccaagattt agttgttaat agtggtcgca
    20581 atctcattat cgagcagatg ctgatctact ttttgcaggc tgttcagata gatgatatat
    20641 tgcgcattca ggcacggatt attcatcata cgagacggtc agctataatt gattacgata
    20701 tttatcatgg tcaccagatt gtttcaaaag caaatgtgac tgttaaaatt aattagaaac
    20761 taggagaaaa gatgataaca ttaaaatcag ctcgtgaaat cgaagctatg gacaaggctg
    20821 gtgattttct agcaagtatt catataggct tacgtgattt gattaagcca ggcgtagata
    20881 tgtgggaagt tgaagaatat gtccgccgtc gttgtaaaga agaaaatttc cttccacttc
    20941 agattggggt tgacggtgcc atgatggact atccttatgc tacctgttgc tctcttaacg
    21001 atgaagtggc tcacgctttc cctcgtcatt atatcttgaa agatggtgat ttgctcaaag
    21061 ttgatatggt tttgggaggt cccattgcta aatccgacct gaatgtctca aaattaaact
    21121 tcaacaatgt tgaacaaatg aaaaaataca ctcagagcta ttctggtggt ttagcagact
    21181 catgttgggc ttatgctgtt ggtacaccgt ccgaagaagt caaaaacttg atggatgtaa
    21241 ccaaagaagc tatgtacaag ggtattgagc aagctgttgt tggaaatcgt atcggtgata
    21301 tcggtgcggc tattcaagaa tacgctgaaa gtcgtggtta cggtgtagtg cgtgatttgg
    21361 ttggtcatgg tgttggccca actatgcacg aagaaccaat ggttcctaac tatggtattg
    21421 caggtcgtgg actccgtctt cgtgaaggaa tggtcttaac cattgaacca atgatcaata
    21481 caggcgattg ggaaattgat acagatatga aaactggttg ggcgcataag accattgacg
    21541 gtggattgtc atgtcagtat gaacaccaat ttgtcattac gaaagatgga cctgttatct
    21601 tgactagcca aggtgaagaa ggaacttatt aataaaaagt gaaaagacta ctggaagttt
    21661 attttgataa aaaatccagt agatcttttc ataataaaac gcattgtatc aagtgttagg
    21721 agctgatatc atgcgttttt ctgcttttaa gattttttcc aactctgttt gtaagcgcat
    21781 cataacaaag ggtctaggat tcagggctct cctcctatat actattagta aagtaaaact
    21841 aagagaggat attttagtgt cgcagtctat tgttcctgta gagattccac aatattgtcg
    21901 ttttgattct aaaaagagaa atggaattct gtttaacgtt cgtattgcca atcttaaatt
    21961 tacctttttt agattagact tcctgcgaaa taaaatatgg tatagtagtt ctatgaatga
    22021 tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt cttgttggtg ttcagcgcac
    22081 gacttttgaa gagatgttag ctgtattaaa aacagcttat caacttaaac acgcaaaagg
    22141 tggacgaaaa cctaaattaa gcctagaaga ccttcttatg gccactcttc aatatgtgcg
    22201 agaatatcga acttatgaag aaattgcggc tgtttttggt atccacgaaa gcaacttaat
    22261 ccgtcggagc taatgggttg aagtaactct tgttcaaagt ggtgttacga tttcaagaac
    22321 tcctctcagc tctgaggcca cggtaatgat tgatgcgacg gaagtaaaaa tcaatcgccc
    22381 taaaaaaaca attagcgaat tattcttgta aaaaaatgcc acgctatgaa ggctcaagcg
    22441 attgtcacaa gtcaagggag aattgtttct ttggatatca ctgtgaacta ttgtcatgat
    22501 atgaagttgt tcaaaatgag ttgcagaaat atcggacaag ctggtaaaat cttggctgac
    22561 agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg taaatccagc
    22621 aaactcaagc cgctaacagt tgaagataaa gcctgtaacc atgcgctatc caaggagaga
    22681 agcaaggttg agaacatctt tgccaaagta aaaacgttta aaataatttc aacaacctat
    22741 cgaaatcatc gtaaacgctt cggattacga atgaatttga gtgctggtat tatcaatcat
    22801 gaactaggat tctagttttg caggaagtct attgaggtat tgagctagtt tatgaaaaaa
    22861 ttgggtgaaa agtcgagtgt tttagaaacc cacagtgtag tattctagtt tcaatccact
    22921 atattttgct actccccgta aagtttctat tttccctgat ttctgatata atagaaatat
    22981 tgacttcaag agtaaggaag agaagatgaa cgcattatta aatggaatga atgaccgtca
    23041 ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc atggcagggg ctggttctgg
    23101 aaagactcgt gttttaaccc accgtatcgc ttatttgatt gatgaaaagc tggtcaatcc
    23161 ttggaatatc ttggccatta cctttaccaa caaggctgcg cgtgagatga aagagcgtgc
    23221 ttatagcctc aatccagcta ctcaggactg tctgattgcg accttccact ccatgtgtgt
    23281 gcgtattttg cgtcgcgatg cggaccatat tggctacaat cgtaatttta caattgtgga
    23341 tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa cagttgaact tggatcctaa
    23401 aaaatggaat gaacgaacta ttttggggac catttccaat gctaagaata atttgattga
    23461 tgatgttgct tatgctgccc aagctggcga tatgtatacg caaattgtgg cccagtgtta
    23521 tacagcctat caaaaagaac ttcgtcagtc tgaatccgtt gactttgatg atttgattat
    23581 gctgaccttg cgtctctttg atcaaaatcc tgatgttttg acctactacc agcaaaaatt
    23641 ccaatacatc cacgttgatg agtaccaaga taccaaccac gctcagtacc aattggtcaa
    23701 actcttggct tcccgtttta aaaatatctg tgtggttggg gatgcggacc agtctatcta
    23761 cggttggcgt ggtgctgata tgcagaatat cttggacttt gaaaaggatt accccaaagc
    23821 caaggttgtc ttgctggagg aaaattaccg ctcaaccaaa accattctcc aagcggccaa
    23881 cgaggttatt aaaaataata aaaatcgccg tcctaaaaat ctctggactc aaaacgctga
    23941 tggggagcaa atcgtttact atcgtgccga tgatgagctg gatgaggctg tatttgtagc
    24001 cagaaccatc gatgaactta gtcgcagtca aaacttcctt cataaggatt ttgcagttct
    24061 ctatcggact aatgcccagt cccgtacaat tgaggaagcc ctgctcaagt ctaacattcc
    24121 ttataccatg gttggcggaa ccaaattcta cagccgtaag gaaattcgcg atattattgc
    24181 ttatctcaac cttattgcta atttgagtga caatattagt tttgagcgta ttatcaacga
    24241 gcctaaacgt ggaattggtc taggtacagt tgagaaaatc cgtgattttg caaatttgca
    24301 aaatatgtct atgctggatg cttctgctaa tattatgttg tctggtatca agggtaaggc
    24361 agcccaatct atctgggatt ttgccaatat gatgcttgat ttgcgggagc agctagacca
    24421 cttaagcatt acagagttgg ttgagtccgt cctagaaaaa acaggttatg tcgatattct
    24481 taacgtccaa gcgactctag aaagcaaggc acgggttgaa aatatcgaag agtttctttc
    24541 tgttacgaag aactttgatg acaccacgga tgtgacagaa gaggaaactg gtctggacaa
    24601 actgagtcgt ttcttaaatg acttggcttt gattgccgac acagattcag gtagtcagga
    24661 gacatcagaa gtgaccttga tgaccctgca tgctgccaaa ggtctcgaat ttccagttgt
    24721 ctttttgatt gggatggaag aaaatgtctt tccacttagt cgtgcgactg aagatccaga
    24781 tgaattagaa gaagagcgcc gtctagccta tgtaggtatc acgcgtgcag agaaaattct
    24841 ctatctgacc aatgccaact cacgcttgct ttttggtcgt accaattata accgtccgac
    24901 tcgttttatt aacgaaatca gttcagactt gcttgagtat caaggtctgg ctcgtcctgc
    24961 aaatacaagc tttaaggcat catatagcag tggtagtatt tcctttggtc aaggtatgag
    25021 tttggctcag gctcttcaag accgtaaacg cggtgctgcc ccaaaatcaa tccagtcaag
    25081 cggtcttcca tttggtcaat ttacagctgg cgcaaaacca gcatctagcg aggcaaattg
    25141 gtccattggt gatattgctc tccacaagaa atggggagag ggaaccgttc tggaagtttc
    25201 aggtagcggt gctaggcagg aattgaaaat caatttccca gaagtaggtt tgaaaaaact
    25261 tttagccagt gtggctccaa ttgagaaaaa aatctaattt tccatccttc tcacgaataa
    25321 taaagtgagg aggattttta tgtacagtat ttcattccaa gaagattcac tattaccaag
    25381 agaaaggctg gccaaggaag gagttgaagc gcttagtaac caagagttgc tagctatttt
    25441 actcaggaca ggaacacgtc aagttagcgt ttttgaaatt gcccaaaaag tcttgaacaa
    25501 tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag gaattgcaga gtttgtctgg
    25561 tattgggcgt gttaaggcca tagaattaca agctatgatt gaactggggc atcgtattca
    25621 caaacacgag actcttgaaa tggaaagtat tctcagcagt caaaagttgg ccaagaagat
    25681 gcagcaggaa ttaggggata aaaaacaaga gcacctggtg gcactctatc tcaatactca
    25741 aaatcaaatc atccatcagc agaccatttt tatcgggtct gtaactcgta gtatcgctga
    25801 accgcgagag attcttcact atgcaatcaa gcatatggcg acttctctta tcttggtcca
    25861 caatcatcct tcaggagcgg tagcgcctag ccaaaatgat gatcatgtca ctaaacttgt
    25921 taaagaagcc tgcgaattga tggggattgt tctcttggac catttgattg tctctcattc
    25981 taattacttt agttatcgtg aaaagacaga tttaatctaa agttcattaa cgacatagtc
    26041 aaagagtttt ttatctttgg gacgattttc aaaaagaagt tctggatgcc attggacacc
    26101 gagaaaggcg acatcatccg tactcatgac agcctcaatg ataccatctt taggatcatg
    26161 agccacaact tttaaatttg gtgctaagtc cttgatgctc tggtggtgga aggagttgat
    26221 atgagagatt tctccataga tttcttggag aacggtatct ggttctgtta ccaagcgttg
    26281 agttgtgtac tcaacagaag aatcctgcca atggtcttcg atatcttggt acaaagttcc
    26341 acccatggca acgttaaaga gttgggtacc acggcagaca gagaaaatgg gctttttctg
    26401 tttaatagct tccttgatga gggtcagttc gaagatatct ctttgaaggt gatagtcatc
    26461 gctatcaatg gttttgggtt cgccataaaa ttttggatcg acattttgcc cacctgtcaa
    26521 gatgagcttg tcaatcaaac tgatatagtg gcaggccatt tcttgatcac caatcggtag
    26581 gatgatggga atccctccag catctttaac gccttcaaca aagccttttg ctgcgtagct
    26641 catcatgatg tcatcatctg gatgagcttt ttcgtttcct gtaatcccaa taactggttt
    26701 tttcataaaa tgattttcgc tttctaatcc tcttttcgca tgaagtagag gagggtttgg
    26761 agttcacttg tcaaatcgac atactgaacg accacgtctt ttggtaaatg cagatggact
    26821 ggtgaaaaac tgagaattcc tttcacacca gcatcaacca agagattagc aacctcttgt
    26881 gacttgacgc tgggaacagt taggatagca gtcttcacat cagcatcctt gattttatcc
    26941 ttgatctgag aaatcccgta aatgggaatc ccgtcaggag tttgggtacc gacttcagga
    27001 tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt tacgttcgtg gaagcggtag
    27061 tggagaaggg catggcccat atttccaata ccaaccagca tgacattggt aatagagttg
    27121 tcattgagca aatcggcaaa aaatgtcatt agttttttga catcatagcc aaaaccacga
    27181 cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg tcgctgaatc aataccgata
    27241 gcctctgcaa tttgcttaga gttggcacgt tcaatctttt ctgcatgaaa tctcttaaaa
    27301 attcgatagt agagagagag tctttttgct gtagcttttg gaatagcaaa ctgtttatct
    27361 ttcacaaaat cacaaccttt ctattcttct attttataga aacattgtga aaaaatcaac
    27421 aaaaataaga aaaaactaag aaaaatctta gttttgatgt aaaaaatctg catgagatag
    27481 aaaacggtag aggtctccga ccagaccctg ataaactttt tggcccctaa aagtcagaga
    27541 agtcacataa agtgtatctg gtaaggttac acatcctgac aaagtcaaca tgagagcctc
    27601 atgatcctca tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa
    27661 cattttggct ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga
    27721 ggaagtagaa tttttcctga tgaatatggt ggtcttctga tttgaaaata tcaactagac
    27781 gaaggccaaa cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga
    27841 ttttgagttg gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat
    27901 agttaccaac cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag
    27961 ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat
    28021 ggctaacctc cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta
    28081 ttttgtggcg acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac
    28141 atggcttcaa gaacatggct ggattggaca acgcctgcag tacaggctga gccagtagag
    28201 attgaaattc cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat
    28261 ccaatattga gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaatgccc
    28321 tccagctctg ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt
    28381 ttttctaggt cttcttttag ggctgcaacc atgcctacga tagcaggcag attttcagtt
    28441 cctgcacgtt ttttctgttc ctggtctccg ccatgtagat aggaatcaaa gtccatgcta
    28501 gatgcgtaga gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga
    28561 aaatcaatgc ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca
    28621 acatgatagg cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggcagtagg
    28681 tttcctgtct cattattggc aaacatggta gaaaccaaaa tcgtatcgtc acgtaaagcc
    28741 ttttgaattt gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaac
    28801 ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt
    28861 gtgatgatat gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta
    28921 ttgccttcag tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg
    28981 gctagttcct gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata
    29041 ctagaaggat ttccgtgggt ttcttgcata accttggtca tagctgaaat agcaactgct
    29101 gacataggag tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta
    29161 ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca
    29221 attaactcac tagcagtgat gtagcataca tttttaggag ttttttcttt tgttgctact
    29281 gaatcagtca caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg
    29341 acgaagagac cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt
    29401 ttagaagctt cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc
    29461 ttaccttcaa catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag
    29521 tcgataatgg cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct
    29581 gaatttttag ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt
    29641 tttgcgaata ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc
    29701 tgaacggcat gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg
    29761 gcaactagtt ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag
    29821 ccaaaatatg gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc
    29881 atgattaaca attccattag gtggttgttg acagggaaac ttgttgattg gatgatgtaa
    29941 acatcataac cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga
    30001 cgtgatgata gttttccaag tgggacacca acagcttggg caattttttg tgcaatctct
    30061 tggttagagt tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct
    30121 ctgtaaactt tataaatcct agttatattt accttacata tatgaactgg gatttgtgta
    30181 tttttatctt ttctatttta ccaaaaaatg gagattattt cagctatttt tcatactttt
    30241 gacaaatcga accaattttg aaggagcttt ttggtaggaa atctgatttt tctctaaaaa
    30301 ttgtcggaaa tcctgtttgc cttgctcatg attttccact tcaagctcca attcgtaatc
    30361 tgttatatca aagtatcggc tctgatccag tgccatgaga ccaatagctg ttttcatttc
    30421 atagcgaagc gttgttagac aaccaagaac ctgccagttc ttactttgga taccatgttt
    30481 cgccaattca tccagtacta gcccttgagg aagttcttcc ttactcagat agttctcagc
    30541 atcttttagt tgcaattttt ggttgtattc catgtttcca acactctgcg ggactttgag
    30601 tgtcaactca gcccagtctt caaaggttcg aatgcgcata gcgactttct tttctcgcag
    30661 ttcaaaatca ggcgtgtcga tgtagtaatt tgtttgaaga acaggagtga cacctgtgaa
    30721 ctggtctttt agacgattgt attcatcttt tttcaatagt gttttcaatt caatttctaa
    30781 atgtttcatt tttcttacct ttttttatcg ttgaaagcgg atttatggta taataagcat
    30841 tgtatttatt gtatatgaat ctggagaaaa aatcaaagat atttttgacg gataatatga
    30901 gaacaaggga gaatatatga ccttagaatg ggaagaattt ctagatcctt acattcaagc
    30961 tgttggtgag ttaaagatta aacttcgtgg tattcgtaag caatatcgta agcaaaataa
    31021 gcattctcca attgagtttg tgaccggtcg agttaagcca attgagagca tcaaagaaaa
    31081 aatggctcgt cgtggcatta cttatgcgac cttggaacac gatttgcagg atattgctgg
    31141 cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa gtagtggata ttttgcacaa
    31201 gcgtcaggat atgcgaatca tacaggagcg agattacatt actcatagaa aagcatcagg
    31261 ctatcgttcc tatcatgtgg tagtagaata tacggttgat accatcaatg gagttaagac
    31321 tattttggca gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa cgatagaaca
    31381 ttctctcaac tacaagtacc aaggggattt cccagatgag attaagaagc gactggaaat
    31441 tacagctaga atcgcccatc agttggatga agaaatgggt gaaattcgtg atgatatcca
    31501 agaagctcag gcactttttg atcctttgag tagaaaatta aatgacggtg taggaaacag
    31561 tgacgataca gatgaagaat acaggtaaac gaattgatct gatagccaat agaaaaccgc
    31621 agagtcaaag ggttttgtat gaattgcgag atcgtttgaa gagaaatcag tttatactca
    31681 atgataccaa tccggatatt gtcatttcca ttggcgggga tggtatgctc ttgtcggcct
    31741 ttcataagta cgaaaatcag cttgagaagg tccgctttat cggtcttcac actggacatt
    31801 tgggcttcta tacagattat cgtgattttg agttggacaa gctagtgact aatttgcagc
    31861 tagatactgg ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt cttgaaaatg
    31921 gtgaagttaa gattttcaga gcactcaacg aagccagcat ccgcaggtct gatcgaacca
    31981 tggtggcaga tattgtaata aatggtgttc cctttgaacg ttttcgtgga gacgggctaa
    32041 cagtttcgac accgactggt agtactgcct ataacaagtc tcttggcggt gctgttttac
    32101 accctaccat tgaagctttg caattaacgg aaattgccag ccttaataat cgtgtctatc
    32161 gaacactggg ctcttccatt attgtgccta agaaggataa gattgaactt attccaacaa
    32221 gaaacgatta tcatactatt tcggttgaca atagcgttta ttctttccgt aatattgagc
    32281 gtattgagta tcaaatcgcc catcataaga ttcactttgt cgcgactcct agccatacca
    32341 gtttctggaa ccgtgttaag gatgccttta tcggtgaggt ggatgaatga ggtttgaatt
    32401 tatcgcagat gaacatgtca aggttaagac cttcttaaaa aagcacgagg tttctaaggg
    32461 attgctggcc aagattaagt ttcgaggtgg agctattctg gtcaataatc aaccgcaaaa
    32521 tgcaacgtat ctattggacg ttggagacta cgttaccatt gacattcccg ctgagaaagg
    32581 ctttgaaacc ttggaggcta ttgagcttcc attagatatt ctctatgagg atgaccactt
    32641 tctagtcttg aataaaccct atggagtggc ttctattcct agtgttaatc actctaatac
    32701 cattgccaat tttatcaagg gttactatgt caagcaaaat tatgaaaatc agcaggttca
    32761 cattgttacc agactagata gggacacttc tggcttgatg ctctttgcca agcacggtta
    32821 tgcccatgca cgattagaca agcagttgca gaagaaatct atcgagaaac gctactttgc
    32881 tttggttaag ggagatggac atttggaacc agaaggggaa attattgctc cgattgcgcg
    32941 tgatgaagat tccattatta ccagacgagt ggctaaaggc ggaaagtatg cccatacttc
    33001 atacaagatt gtagcttctt atggaaatat tcacttggtc tatattcacc tgcacactgg
    33061 tcgaacccat caaatccgag tccatttttc tcatatcggt tttcctttgc tgggagatga
    33121 tttgtatggt ggtagtctgg aagatggtat tcaacgtcag gctctgcatt gccattacct
    33181 atccttttat catccatttt tagagcaaga cttgcagtta gaaagtccct tgccggatga
    33241 tttcagtaac cttattaccc agttatcaac taatactcta taaaaactgt ctcagagtat
    33301 aattattatc ttaaaggaga aaactcatgg aagtttttga aagtctcaaa gccaaccttg
    33361 ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga gcctcgtatt cttcaagcaa
    33421 caaaacgctt agtaaaagaa acagaagtga ttcctgtttt gcttggaaat cctgaaaaaa
    33481 ttaaaattta tcttgaaatt gaaggaatca tggatggtta tgaggtcatc gaccctcaac
    33541 attatcctca atttgaagaa atggtttctg ccttggtgga gcgtcgcaag ggcaaaatga
    33601 ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa ctactttggt gtgatgttgg
    33661 tttacttggg cttggttgat ggaatggtgt caggagcgat tcactcaaca gcttcaacag
    33721 ttcgcccagc tctacaaatc atcaaaactc gtccaaatgt aactcgtact tcaggagcct
    33781 tcctcatggt tcgtggtacg gaacgttacc tatttggaga ctgtgccatt aatatcaatc
    33841 cagatgcaga agccttggct gaaattgcca tcaactcagc aatcacagct aagatgtttg
    33901 gcatcgaacc taaaattgcc atgttgagct attctactaa aggttcaggg tttggtgaaa
    33961 gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct gaccttgaaa
    34021 tcgatggtga gttgcaattt gatgcggcct ttgttcccga aactgcagct ctgaaagctc
    34081 cgggaagtac agtagctggt caagcaaatg tcttcatctt cccaggtatc gaggcaggaa
    34141 atatcggtta caagatggct gaacgcctgg gtggctttgc ggctgtagga cctgttttgc
    34201 aaggtttaaa caagccagtt aatgatcttt ctcgtggatg taatgcagat gatgtttaca
    34261 agttgaccct catcacagca gctcaagcag ttcatcaata gtgaaaacta taaagtgata
    34321 tactatgcta tactgtagtt atgaaactat gtacgaaaag cactgccatt aattcctgag
    34381 aactaaatta ctgattggtg tcaaaaagga aaacttccaa gcgatgatat cctgtctata
    34441 cacgacctat agaaatctgt aatatacata tccgtaaaac gataaattcc ctttttgatt
    34501 ttaaatgagt atgaaaagag aattttttgg ctctttgtca actgtagtgg gttgaagt
//
LOCUS       DAVLAQ010000021        34488 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000021 DAVLAQ010000000
VERSION     DAVLAQ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.021"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            559..1011
                     /locus_tag="VXB71_000989"
     CDS             559..1011
                     /locus_tag="VXB71_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0451118.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKAGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1030..2367
                     /locus_tag="VXB71_000990"
     CDS             1030..2367
                     /locus_tag="VXB71_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0451119.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2446..3330
                     /locus_tag="VXB71_000991"
     CDS             2446..3330
                     /locus_tag="VXB71_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0451120.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWIINGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3330..4163
                     /locus_tag="VXB71_000992"
     CDS             3330..4163
                     /locus_tag="VXB71_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0451121.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4181..6274
                     /gene="nanB"
                     /locus_tag="VXB71_000993"
     CDS             4181..6274
                     /gene="nanB"
                     /locus_tag="VXB71_000993"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0451122.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6286..7389
                     /locus_tag="VXB71_000994"
     CDS             6286..7389
                     /locus_tag="VXB71_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0451123.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7563..8261
                     /locus_tag="VXB71_000995"
     CDS             7563..8261
                     /locus_tag="VXB71_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0451124.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8280..9797
                     /locus_tag="VXB71_000996"
     CDS             8280..9797
                     /locus_tag="VXB71_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0451125.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9922..11250
                     /locus_tag="VXB71_000997"
     CDS             9922..11250
                     /locus_tag="VXB71_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0451126.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11502..12368
                     /locus_tag="VXB71_000998"
     CDS             11502..12368
                     /locus_tag="VXB71_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0451127.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12384..13223
                     /locus_tag="VXB71_000999"
     CDS             12384..13223
                     /locus_tag="VXB71_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0451128.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13495..13947
                     /locus_tag="VXB71_001000"
     CDS             13495..13947
                     /locus_tag="VXB71_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0451129.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14044..14388
                     /locus_tag="VXB71_001001"
     CDS             14044..14388
                     /locus_tag="VXB71_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451130.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14675..15319
                     /locus_tag="VXB71_001002"
     CDS             14675..15319
                     /locus_tag="VXB71_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0451131.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15488..16405
                     /locus_tag="VXB71_001003"
     CDS             15488..16405
                     /locus_tag="VXB71_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0451132.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            16423..17307
                     /locus_tag="VXB71_001004"
     CDS             16423..17307
                     /locus_tag="VXB71_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0451133.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17323..18174)
                     /locus_tag="VXB71_001005"
     CDS             complement(17323..18174)
                     /locus_tag="VXB71_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0451134.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18374..20431
                     /gene="pbp2b"
                     /locus_tag="VXB71_001006"
     CDS             18374..20431
                     /gene="pbp2b"
                     /locus_tag="VXB71_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0451135.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20442..21038
                     /gene="recR"
                     /locus_tag="VXB71_001007"
     CDS             20442..21038
                     /gene="recR"
                     /locus_tag="VXB71_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0451136.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21214..22257
                     /locus_tag="VXB71_001008"
     CDS             21214..22257
                     /locus_tag="VXB71_001008"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0451137.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22341..23714
                     /locus_tag="VXB71_001009"
     CDS             22341..23714
                     /locus_tag="VXB71_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0451138.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            23701..24312
                     /locus_tag="VXB71_001010"
     CDS             23701..24312
                     /locus_tag="VXB71_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0451139.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24403..25107
                     /locus_tag="VXB71_001011"
     CDS             24403..25107
                     /locus_tag="VXB71_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0451140.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25326..26699
                     /gene="ftsA"
                     /locus_tag="VXB71_001012"
     CDS             25326..26699
                     /gene="ftsA"
                     /locus_tag="VXB71_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0451141.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26716..27975
                     /gene="ftsZ"
                     /locus_tag="VXB71_001013"
     CDS             26716..27975
                     /gene="ftsZ"
                     /locus_tag="VXB71_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0451142.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27980..28651
                     /locus_tag="VXB71_001014"
     CDS             27980..28651
                     /locus_tag="VXB71_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0451143.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28661..29200
                     /locus_tag="VXB71_001015"
     CDS             28661..29200
                     /locus_tag="VXB71_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0451144.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29200..29463
                     /locus_tag="VXB71_001016"
     CDS             29200..29463
                     /locus_tag="VXB71_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0451145.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29460..30245
                     /locus_tag="VXB71_001017"
     CDS             29460..30245
                     /locus_tag="VXB71_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0451146.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30254..31042
                     /gene="divIVA"
                     /locus_tag="VXB71_001018"
     CDS             30254..31042
                     /gene="divIVA"
                     /locus_tag="VXB71_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0451147.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31390..34182
                     /locus_tag="VXB71_001019"
     CDS             31390..34182
                     /locus_tag="VXB71_001019"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0451148.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10613 a         6076 c         7495 g        10304 t
ORIGIN      
        1 acaaaactaa tttagagaat gaaatataga gtatttctct cttaaaagtt tttggtgaaa
       61 cgagatgtag aaaggagatt tagccaaaga gtctattagt gctagaataa tagattagaa
      121 ttattttaga aaaacgaagt gagcagctta taaattcaag tccccaaata gattcatact
      181 agtatctttt gcaaaaaata aagggcgact tccttcatga atatcaattt catctataag
      241 gaaggtagct aattgaacta acttatttat tctgtttgtc gctagaaaaa tcagacctcc
      301 ttgtgaagat tgaggagata cttaatgaaa atcaaagaag aaactagcaa gctagtagca
      361 gattgcccaa aacaccgctt tgaggttgta gataagactg acgtatataa tccaaggtga
      421 agcgactgtg gtttgaagag attttcaaag agtataggct agagagtagt gtttttatgt
      481 ccttctagta gaaaatgcta gacagaagaa tggggaactt ggataggaga aatagattga
      541 gaaaggaggt tagaagagat gattattaca aaaattagcc gtttaggaac ttatgtggga
      601 gtaaatccac attttgcaac attaatagat tttctagaaa aagcaggact agaaaattta
      661 acagaaggtt cgattgctat cgatggtaat cgattgtttg ggaattgctt tacttatcta
      721 gcagatggtc aagcaggggc tttctttgaa acacaccaaa aatatttgga tattcattta
      781 gttttggaaa acgaagaagc catggctgtt acatcgccgg aaaatgtaag cgttacccaa
      841 gaatatgatg aagagaaaga tattgaatta tacacaggga aagtggaaca gttggttcag
      901 ttgagagctg gcgaatgcct catcactttt ccagaagatt tacatcaacc caaggttcgt
      961 ataaatgatg aacctgtgaa aaaagttgtc tttaaagttg cgatttctta atgtagaaag
     1021 agaagaacga tgaaaaaaat gagaaagttt ttatgtctag ctggaattgc gctagcggct
     1081 gttgccttgg tagcttgttc aggaaaaaaa gaagctacaa ctagtactga accaccaaca
     1141 gaattatctg gtgagattac aatgtggcac tcctttactc aaggaccccg tttagaaagt
     1201 attcaaaaat cagcagatgc tttcatgcaa aagcatccaa aaacgaaaat caagattgaa
     1261 acattttctt ggaatgactt ctatactaaa tggactacag gtttagcaaa tggaaatgtg
     1321 ccagatatca gtacagctct tcctaaccaa gtaatggaaa tggtcaactc agatgctttg
     1381 gttccgctaa atgattctat caagcgtatt ggacaagata aatttaacga aactgcctta
     1441 aatgaagcaa aaatcggaga tgattactac tctgttcctc tttattcaca tgcacaagtc
     1501 atgtgggtta gaacagattt gttaaaagaa cataatattg aggttcctaa aacttgggat
     1561 caactctatg aagcttctaa aaaattgaaa gaagctggag tttatggctt gtctgttccg
     1621 tttggaacaa atgacttaat ggcaacacgt ttcttgaact tctacgtacg tagtggtgga
     1681 ggaagcctct taacaaaaga tcttaaagca gacttgacaa gccaacttgc tcaagatggt
     1741 attaaatact gggttaaatt gtataaagaa atctcacctc aagattcttt gaactttaat
     1801 gtccttcaac aagctacctt gttctatcaa ggaaaaacag catttgactt taactctggc
     1861 ttccatatcg gaggaattaa tgccaacagt cctcaattga ttgattcgat tgatgcttat
     1921 cctattccaa aaatcaaaga gtctgataaa gaccaaggaa ttgaaacctc aaacattcca
     1981 atggttgttt ggaaaaattc aaaacatcca gaagttgcta aagcattctt agaagcactt
     2041 tataatgaag aagactacgt taaattcctt gattcaactc cagtaggtat gttgccaact
     2101 attaagggga ttagcgattc tgcagcctat aaagaaaatg aaactcgtaa gaaatttaaa
     2161 catgctgaag aagtaattac tgaagctgtt aaaaaaggta ctgctattgg ttatgaaaat
     2221 ggaccaagtg tacaagctgg tatgttgact aaccaacaca ttattgaaca aatgttccaa
     2281 gatatcatta caaatggaac agatcctatg aaagcagcaa aagaagcaga aaaacaatta
     2341 aacgatttat ttgaggctgt tcagtagatg taaaagacta gaaaataggt gggctagtga
     2401 gctgaaaagc tctagcccaa tcttgtaaaa gaagggagaa ggagaatggt taaagaacgt
     2461 aatttaactc gctggatatt tgttttgcca gctatgatta tcgtaggatt actctttgtt
     2521 tatccgtttt tctcgagtat tttttatagc tttaccaata agcatttgat tatgcctaat
     2581 tataaatttg ttggtttggc taactataaa gctgtgctat cagatcccaa cttctttaat
     2641 gcgttcttta attcaattaa gtggaccgtt ttctcattag ttggtcaagt tttagtaggg
     2701 tttgtattgg ctttagctct tcacagagta cgccacttca agaaattata taggacctta
     2761 ttgattgttc cttgggcatt tcctaccatc gttattgcct tctcttggca gtggattata
     2821 aacggggttt atggctactt acctaatcta atcgtaaaat taggtttaat ggaacataca
     2881 cctgcatttt tgacagatag tacatgggca ttcctatgtt tggtgtttat caacatttgg
     2941 tttggagcac caatgattat ggttaatgtg ctttcagctt tgcaaacagt accagaagaa
     3001 caatttgagg ctgctaagat agatggtgct tcaagttggc aggtgttcaa gtttatcgtc
     3061 tttccacata ttaaagtggt tgtaggactt ctagttgttt tgagaactgt atggatcttt
     3121 aataactttg acattatcta cctcattact ggtggtggac cagccaatgc tacaacgacg
     3181 cttccaattt ttgcttacaa cctgggttgg ggaactaaat tgttgggtcg tgcttcagca
     3241 gttacagtat tgctctttat cttcttggtg gcgatttgct ttatctactt tgctatcatc
     3301 agtaagtggg aaaaggaggg tagaaaataa tgaagaagaa atccagtatt tatttagata
     3361 ttctctcaca tgtactttta gttggtgcga ccatcgttgc aattttccca ttggtatgga
     3421 ttatcatatc ttctgtcaaa gggaaagggg aattaactca gtatccaaca cgattttggc
     3481 ctgaacagtt tacattagat tatttcactc atgttatcaa cgatttgcac ttcattgata
     3541 acattcgaaa cagtttaatc attgccttgg ctacaaccct cattgcgatt attatttctg
     3601 ctatggcagc ctatggtatt gttcgattct ttcctaaatt gggagcaatc atgtcgagac
     3661 tactcgtcat tacctacatt ttcccaccaa ttttgttagc aattccctat tcaattgcca
     3721 ttgctaaagt tgggttaaca aatagtttat ttggcttgat gatggtttat ctatctttta
     3781 gtgttccata tgcagtttgg ctcttagttg gatttttcca aacagttcca attggaattg
     3841 aagaagcggc tagaattgat ggtgcaaata aatttgttac gttttataaa gttgtgctac
     3901 cgattgtagc accaggtatt gtagcaacag ctatttatac atttatcaat gcttggaatg
     3961 aattcctgta tgccttgatt ttgattaaca atacaggaaa gatgacagta gcagtagccc
     4021 ttcgttcact taatggttca gaaatactag actggggaga tatgatggca gcgtctgtta
     4081 ttgtagttct tccatcaatt attttcttct ctatcatcca aaataagatt gcaagtggat
     4141 tatcagaagg atctgtgaag tagacgaaag aaggaaaaaa atgaataaaa gaggtcttta
     4201 ttcaaaacta ggaatttctg ttgtaggcat tagtctttta atgggagtcc ccactttgat
     4261 tcatgcgaat gaattaaact atggtcaact gtccatatct cctatttttc aaggaggctc
     4321 atatcaactg aacaataaga gtatagatat cagccctttg ttattagata aattgtctgg
     4381 agagagtcag acagtagtaa tgaaatttaa agcagatgaa ccaaactctc ttcaagcttt
     4441 gtttggccta tctaatagta aagcaggctt taaaaataat tacttttcaa ttttcatgag
     4501 agattctggt gagataggtg tagaaataag agacgcccaa aagggaataa attatttatt
     4561 ttccagacca gcttcattat ggggaaaaca taaaggacag gcagttgaaa atacactagt
     4621 atttgtatct gattctaaag ataaaacata cacaatgtat gttaatggaa tagaagtgtt
     4681 ctctgaaaca gttgatacat ttttgccaat ttcaaatata aatggtatag ataaggcaac
     4741 actaggagct gttaatcgtg aaggtaagga acattacctc gcaaaaggaa gtattggtga
     4801 aatcagtcta tttaacaaag caattagtga tcaggaagtt tcaactattc ccttatcaaa
     4861 tccatttcag ttaattttcc aatcaggaga ttctactcaa gctaactatt ttagaatacc
     4921 gacactatat acattaagta gtggaagagt tctatcaagt attgatgcac gttatggtgg
     4981 gactcatgat tctaaaagta agattaatat tgccacttct tatagtgatg ataatgggaa
     5041 aacgtggagt gagccaattt ttgctatgaa gtttaatgac tatgaggagc agttagttta
     5101 ctggccacga gataataaat taaagaatag tcaaattagt ggaagtgctt cattcataga
     5161 ttcatccatt gttgaagata aaaaatctgg gaaaacgata ttactagctg atgttatgcc
     5221 tgcgggtatt ggaaataata atgcaaataa agccgactca ggttttaaag aaataaatgg
     5281 tcattattat ttaaaactaa agaagaatgg agataacgat ttccgttata cagttagaga
     5341 aaatggtgtc gtttatgatg aaacaactaa taaacctaca aattatacta taaatgataa
     5401 gtatgaagtt ttggagggag gaaagtcttt aacagtcgaa caatattcgg ttgattttga
     5461 tagtggctct ttaagagaaa aacataatgg aaaacaggtc cctatgaatg ttttctacaa
     5521 agattcgtta tttaaagtga ctcctactaa ttatatagca atgacaacta gtcagaatag
     5581 aggagagagt tgggaacaat ttaagttgtt gcctccgttc ttaggagaaa aacataatgg
     5641 aacttactta tgtcccggac aaggtttagc attaaaatca agtaacagat tgatttttgc
     5701 aacatatact agtggagaac taacctatct catttctgat gatagtggtc aaacatggaa
     5761 gaaatcctca gcttcaattc cgtttaaaaa tgcaacagca gaagcacaaa tggttgaact
     5821 gagagatggt gtgattagaa cattctttag aaccactaca ggtaagatag cttatatgac
     5881 tagtagagat tctggagaaa catggtcgga agtttcgtat attgatggaa tccaacaaac
     5941 ttcatatggc acacaagtat ctgcaattaa atactctcaa ttaattgatg gaaaagaagc
     6001 agtcattttg agtacaccaa attctagaag tggccgtaag ggaggtcaat tagttgtcgg
     6061 tttagtcaat aaagaagatg atagtattga ttggaaatac cactatgata ttgatttgcc
     6121 ttcgtatggt tatgcctatt ctgcgattac agaattgcca aatcatcaca taggtgtact
     6181 gtttgaaaaa tatgattcgt ggtcgagaaa tgaattgcat ttaagcaatg tagttcagta
     6241 tatagatttg gaaattaatg atttaacaaa ataaaggaga aaaacatggt taaatacggt
     6301 gttgttggag cagggtattt tggagctgaa ttggctcgct acatgcaaaa gaatgatgga
     6361 gcagagatta ctcttctcta tgatccagat aatgcagagg cgattgcaga agaattggga
     6421 gcaaaagtag caagttcctt agatgagttg gtttctagcg atgaagtaga ttgtgttatc
     6481 gtcgcaactc caaataatct tcataaggaa ccggttatta aggctgcaca gcatggtaaa
     6541 aatgttttct gtgaaaaacc aattgcgctt tcttatcaag attgtcgcga gatggtagat
     6601 gcgtgtaaag aaaacaatgt aacctttatg gcaggacata ttatgaattt ctttaatggt
     6661 gttcatcatg caaaagaact cattaatcaa ggagttatcg gagacgttct atattgtcat
     6721 acagctcgta atggttggga agaacaacaa ccgtcagtat catggaaaaa aattcgtgaa
     6781 aaatcaggtg gtcacttgta tcaccacatc catgaattgg attgcgttca attccttatg
     6841 gggggcatgc ctgaaactgt aaccatgaca ggtggaaatg tggcccatga aggtgaacat
     6901 ttcggtgatg aagatgatat gatttttgtc aatatggaat tttctaataa gcgttttgct
     6961 ttgttagaat ggggttcagc ttatcgttgg ggtgaacatt atgtcttaat ccaaggaagc
     7021 aaaggtgcca tccgcttaga cttattcaac tgtaaaggaa ctcttaagct agatgggcaa
     7081 gaaagctatt tcttgattca cgaatcgcaa gaagaagatg atgatcggac tcgtatctat
     7141 catagtacag agatggatgg agcaattgct tatggtaaac caggtaaacg tactccatta
     7201 tggctatcat ctgtcattga taaagaaatg cgctatctgc atgagattat ggaaggagct
     7261 ccagtatcag aagaatttgc aaaacttttg acaggtgaag ctgccctaga agcaattgct
     7321 actgcagatg cttgtaccca gtctatgttt gaagatcgca aagtaaaatt gtcagaaatt
     7381 gtaaaataaa ttttggtatt ctcctattta taggtcgact tgctcctctg aaagtacttt
     7441 tagaggagct gtttgacttt gctagttttt gaaactgaaa tctattatac tacaaactat
     7501 tgaaagcgtt ttaattttaa ggtataataa tctcatagaa ataaagaaaa ggaggaaaga
     7561 ggatgccaca gattagcaaa gaagccttga ttgagcaaat caaagatgga atcatcgttt
     7621 cttgtcaggc tcttcctcat gaaccgcttt atacagaagc gggaggggtg attcccttgc
     7681 tggtcaaagc ggctgagcaa ggtggagcag tcggtatccg agcaaacagt gttcgcgata
     7741 tcaaggaaat taaggaggtc actaaacttc caatcattgg gattatcaaa cgtgattatc
     7801 cacctcagga acccttcatc acggctacta tgaaagaagt tgatgaattg gcagaactgg
     7861 acatcgaggt gattgctctg gattgtacca agcgtgaacg ctacgatggt ttggaaattc
     7921 aagagttcat tcgtcaggtt aaggagaaat atcctaatca gcttttgatg gctgatacta
     7981 gtatcttcga agaagggcta gcagctgtag aagcaggaat tgactttgtc ggaacaacct
     8041 tatcaggcta cacatcctac agtccaaaag tagacggtcc agattttgaa ttgattaaga
     8101 aactctgtga tgccggtgta gatgtcattg cagaaggaaa aattcataca ccagaacaag
     8161 ccaaacaaat ccttgaatat ggagtgcgag gcatcgttgt tggtggcgcc attactagac
     8221 caaaagagat tacagaacgc ttcgttgcta gtcttaaata agatgtgagg gggagtttta
     8281 tgtttaaagt tttacaaaaa gttggaaaag cttttatgtt acctatagct atacttcctg
     8341 cagcaggtct acttttgggg attggtggtg cactttcaaa cccaaccacg atagcaactt
     8401 atccaatact agacaatagt atttttcaat caatattcca agtaatgagc tctgcaggag
     8461 aggttgtatt cagtaatttg tcactacttc tctgtgtggg attatgtatt ggcttagcga
     8521 aacgagataa aggaaccgct gcgttagcag gagtaactgg ttacttagtt atgactgcaa
     8581 cgatcaaagc tttggtaaaa ctttttatgg cagaaggatc tgcaattgat actggagtta
     8641 ttggagcatt agctgtcgga atagttgccg tatatttgca caaccgatat aacaatattc
     8701 aattaccttc cgctttagga ttctttggag gttcacgctt cgttcctatt gttacatcgt
     8761 tctcttctat cttgattggc tttgtcttct ttgttatttg gccacctttc caacaacttc
     8821 ttgtttctac aggtggatat atttctcagg cgggtccaat tggaactttt ctatatggat
     8881 ttttaatgag actttctgga gcagtaggct tacatcatat aatttaccct atgttttggt
     8941 atactgaact tggtggtgtt gaaactattg caggacaaac agtggttgga gctcaaaaaa
     9001 tattttttgc tcaattagcc gatccggccc attctggatt atttacagaa ggaacaaggt
     9061 tttttgcagg tcgtttctca acaatgatgt tcggtttacc ggctgcctgt ttagcgatgt
     9121 accatagtgt tcctaaaaat cgtcgtaaaa aatacgcggg tttgtttttt ggagttgctt
     9181 taacatcttt tattaccggt attacagaac caattgaatt tatgtttcta ttcgtcagtc
     9241 cggttctata tgttgttcac gcattccttg atggtgttag cttctttatt gcagacgtct
     9301 taaatatttc aataggaaac acattttcag gaggtgtaat cgatttcact ttatttggaa
     9361 ttttgcaggg gaacgctaag acgaattggg ttcttcagat tccaattgga cttatttgga
     9421 gtgttttgta ttatattatt tttagatggt tcattactca attcaatgtt ctaacgccag
     9481 gacgaggaga agaagtagat tctaaagaaa tttctgaatc cgcagattca acttcaaata
     9541 ctgcagatta tttaaaacag gatagcctac aaattatcag agccttgggt ggatcaaata
     9601 atatagaaga tgtagatgct tgtgtgacac gtttacgtgt agctgtaaaa gaagttaatc
     9661 aagttgataa agcactttta aaacaaattg gtgcagttga tgtcttagaa gtgaagggtg
     9721 gcattcaagc aatctatgga gcaaaagcaa tcttatataa aaatagtatt aatgaaattt
     9781 taggtgtaga tgattaagta cttactgact taataaaaaa cagaggagag tgatggatga
     9841 gtaggatgaa atgaaatcgc atacaagaaa taaagaactc attatccaag ttggatacgc
     9901 ttattacata ggagaataca aatgaaattt agaaaattag cttgtacagt acttgcgggt
     9961 gctgcggttc ttggtcttgc tgcttgtggc aattctggcg gaagtaaaga tgctgccaaa
    10021 tcaggtggtg acggtgccaa aacagaaatc acttggtggg cattcccagt atttacccaa
    10081 gaaaaaactg gtgacggtgt tggaacttat gaaaaatcaa tcatcgaagc gtttgaaaaa
    10141 gcaaacccag atataaaagt gaaattggaa accatcgact tcaagtcagg tcctgaaaaa
    10201 atcacaacag ccatcgaagc aggaacagct ccagacgtac tctttgatgc accaggacgt
    10261 atcatccaat acggtaaaaa cggtaaattg gctgagttga atgacctctt cacagatgaa
    10321 tttgttaaag atgtcaacaa tgaaaacatc gtacaagcaa gtaaagctgg agacaaggct
    10381 tatatgtatc cgattagttc tgccccattc tacatggcaa tgaacaagaa aatgttagaa
    10441 gatgctggag tagcaaacct tgtaaaagaa ggttggacaa ctgatgattt tgaaaaagta
    10501 ttgaaagcac ttaaagacaa gggttacaca ccaggttcat tgttcagttc tggtcaaggg
    10561 ggagaccaag gaacacgtgc ctttatctct aacctttata gcggttctgt aacagatgaa
    10621 aaagttagca aatatacaac tgatgatcct aaattcgtca aaggtcttga aaaagcaact
    10681 agctggatta aagacaattt gatcaataat ggttcacaat ttgacggtgg ggcagatatc
    10741 caaaactttg ccaatggtca aacatcttac acaatccttt gggcaccagc tcaaaatggt
    10801 atccaagcta aacttttaga agcaagtaag gtagaagtgg tagaagtacc attcccatca
    10861 gacgaaggta agccagctct tgaatacctt gtaaacgggt ttgcagtatt caacaataaa
    10921 gacgacaaga aagtcgctgc atctaagaaa ttcatccagt ttatcgcaga tgacaaggag
    10981 tggggaccta aagacgtagt tcgtacaggt gctttcccag tccgtacttc atttggaaaa
    11041 ctttatgaag acaaacgcat ggaaacaatc agcggctgga ctcaatacta ctcaccatac
    11101 tacaacacta ttgatggatt tgctgaaatg agaacacttt ggttcccaat gttgcaatct
    11161 gtatcaaatg gtgacgaaaa accagcagat gctttgaaag ccttcactga aaaagcgaac
    11221 gaaacaatca aaaaagctat gaaacaatag tccttagtta ttctataaaa agtagttttt
    11281 taaagaacct aagagtgtat accccctttt ccctctacac agatagtgta agaaaagggg
    11341 gcttttgttt aaaatgtaag aaactgtcac gaaattaaaa tgaagttctt acataagcga
    11401 atcataaaaa atttcatttt gattttaaaa cagttcaaga aagtcaaaaa attattctat
    11461 ttgaaagaga ggtgccgact gtgaaagtca ataaaatccg tatgcgggaa acagtgattt
    11521 cctacgcttt cctagcacca gtattattct tctttgtcat ctttgtgttg gctccgatgg
    11581 tgatgggctt cattacaagt ttctttaact actcaatgac taaatttgag tttgtaggct
    11641 tggataacta tatccgtatg tttaaagatc ctgtctttac aaaatctctg attaacacag
    11701 ttattttggt tattggatct gtaccagttg ttgttctatt ctcactcttt gtagcatctc
    11761 agacctatca tcaaaatgtc attgccagat ccttctaccg tttcgtcttc ttccttcctg
    11821 ttgtaacggg tagtgttgcc gtgacagttg tttggaaatg gatttatgac ccactatcag
    11881 ggattctaaa ctttgtcctt aagtccagcc acatcatcag ccaaaacatt tcttggttgg
    11941 gagataaaaa ctgggcattg atggcgatta tgattattct cttgaccact tcagttggtc
    12001 agcccatcat cctttatatc gctgccatgg ggaatattga caattcactg gttgaagcgg
    12061 cgcgtgttga tggtgcaact gagtttcaag ttttttggaa gattaaatgg ccaagccttc
    12121 ttccaacaac tctttatatt gcaatcatca caacaattaa ctcattccag tgttttgcct
    12181 tgattcagct tttgacatct ggtggtccaa actactcaac aagtaccttg atgtactacc
    12241 tttacgaaaa agccttccaa ttgacagaat acggctatgc caacacaatt ggtgtcttct
    12301 tggcaatcat gattgctatc gtaagctttg ttcaatttaa agtacttgga aacgacgtag
    12361 aatactaaag aaaggagaca gctatgcaat ctacagaaaa aaaaccatta acagccttta
    12421 ctgttatttc aacaatcatt ttgctcttgt tgactgtgct gttcatcttt ccattctact
    12481 ggattttgac aggggcattc aaatcacaac ctgatacaat tgttattcct cctcagtggt
    12541 tccctaaaat gccaaccatg gaaaacttcc aacaactcat ggtgcagaac cctgccttgc
    12601 aatggatgtg gaactcagta tttatctcat tggtaaccat gttcttagtc tgtgcaacct
    12661 catctctagc aggttatgta ttggctaaaa aacgtttcta tggtcaacgc attctatttg
    12721 ctatctttat cgctgctatg gcgcttccaa aacaagttgt ccttgtacca ttggtacgta
    12781 tcgtcaactt catgggaatc cacgatactc tctgggcagt tatcttgcct ttgattggat
    12841 ggccattcgg tgtcttcctc atgaaacagt tcagtgaaaa tatccctaca gagttgcttg
    12901 aatcagctaa aatcgacggt tgtggtgaga ttcgtacctt ctggagtgta gccttcccga
    12961 ttgtgaaacc agggtttgca gcccttgcaa tctttacctt catcaatact tggaatgact
    13021 acttcatgca attggtaatg ttgacttcac gtaacaattt gaccatctca cttggggttg
    13081 cgaccatgca ggctgaaatg gcaaccaact atggtttgat tatggcagga gctgcccttg
    13141 ctgctgttcc aatcgtcaca gtcttcctag tcttccaaaa atccttcaca cagggtatta
    13201 ctatgggagc ggtcaaagga taatactctg agaaaatctc ttcaaactac gtcagcgtca
    13261 ccttgccata cttaagtatt gcctgcggtt agcttcctag tttgttcttc aattttcatt
    13321 gagtatagga aaatcaatct atcaagatac agaagtatat tttatagatt tagagaatat
    13381 agaggttata agtgtctaca aaatggaggg tatgcagtta ctttatgaag ttttgtcaga
    13441 cacttataaa cttaagaatg gttttagtta actatcagaa acgaaggaaa gagtatgatt
    13501 tttgacgatt tgaaaaacat caccttttac aaagggattc atcccaattt agacaaggct
    13561 atcgactatc tctaccaaca tcgtaaagat tcattcgaat taggaaagta tgagattgat
    13621 ggagataaag tctttctagt tgttcaggaa aatgtcctca atcaagttga gaataatcga
    13681 tttgaacacc ataagaacta tgcagatttg catttgctga tagaagggca tgaatattcg
    13741 agctacggtt cacgtatcaa agacgaggca gtagcattcg acgaagcgag tgacattggc
    13801 tttgttcatt gtcatgaaca ctacccactc ttgttgggtt atcacaattt tgcgattttc
    13861 ttcccaggtg agccacatca gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa
    13921 tatctcttta aaattttgat tgattaaaaa taggatgaat tgtttttttg taaagctttg
    13981 ataatactct accatgaaat tgatctttgt gaggtagaga aatgagaata aaatatttaa
    14041 aaattggtat cttctaagta tgctgcaaga gctagtttct tagatggaca ggggattaca
    14101 gttgatgaga tggcttggat aattaggggc attgtgactg cattgattgg tagatacata
    14161 aaattaggta cttatgcagt taagtatggt attagtatgg cgcgctcgat cttaagtagg
    14221 gcagctgcaa ctgcggcagc aagagtagga ttattgacta agatttttgg atggatttta
    14281 cgaatagctg tgctcgcagc tgatgtatat ggtaattttg ccaacaatat tgctgtagct
    14341 tgggatgcac atgataaaat ccctaacaat ggtcgtataa acttttaaaa tgcgagaatg
    14401 aaagcacttt gtattttttt attgtatatg ttagcttgga cagtgcttgc aatgataatc
    14461 cgtggagggc tagatggatt tgatgaacac acttggcgta ctattttaat tgcttcgctg
    14521 tccgggatat atatagatta tatgtccata gataaaagta gaaaaaagtc caaaagaaaa
    14581 aagaaaaaat agatttgttc atggtaggga cttatgaaag ctttactgac aaaaaagaaa
    14641 acagtttaca aagaaaaatg atggaggagc aaacatggca caaaaaggag taagccttat
    14701 caaggcagca tttgatacag ataactttct catgcgtttt agtgagaaag tcttggacat
    14761 cgtgacagcc aatcttcttt ttgtcgtctc ttgtttgccc atcgtgacga ttggagtggc
    14821 taaaatcagc ctctacgaga ccatgttcga agttaagaag agcagacggg tgcctgtttt
    14881 taaaatctat ctaagatctt tcaagcaaaa tctgaaacta ggtcttcagc tgggtttaat
    14941 ggagttagga attgtgtttc ttaccctttc agatctctat cttttctggg gtcaaacagc
    15001 tctgcccttc caattgctga aagccatttg tctaggcatt ctgattttcc ttacgattgt
    15061 gatgttggct agctatccaa tcgcggcacg ttatgattta acttggaaag aagtgttaca
    15121 aaaagggctt atcttggcta gttttaactt tccttggttc ttcctcatgt tagccattct
    15181 tgtcctcatt gtgatggttc tttatctgtc cgccttcagt ctactcttag gtggctcagt
    15241 cttcctactt tttgggtttg gactattggt ctttatccag actggattga tggagaaaat
    15301 tttcgcaaaa taccaatagg agccttattt ctgaaactac tttcaaaggc tccaaacgct
    15361 attctataag cgagaaacta aaatctaagt gtctataaga tattgaaagc cttttcggta
    15421 aagtgtatac taaagaagta aagaaaaatc tgctttagca gaaaataaaa ataataggag
    15481 aaaatctatg tcagatttga aaaaatacga aggtgtcatt ccagccttct acgcatgtta
    15541 tgatgagcaa ggagaagtaa gtccagagcg tacgcgtgcc ttggttcaat acttcattga
    15601 taaaggtgtt caaggtcttt atgtcaatgg ttcttctggt gaatgtatct accaaagcgt
    15661 tgaagatcgc aagttgattt tggaagaagt catggcggta gccaaaggta aattgaccat
    15721 tattgcccat gttgcttgca ataatactaa agatagtatg gaacttgctc gccatgctga
    15781 aagcttggga gtagatgcta ttgcaacgat tccaccaatt tacttccgct tgccagaata
    15841 ctcagttgcc aaatactgga acgatattag ttctgcagct ccaaacacag actacgtgat
    15901 ttacaacatt cctcaattgg caggggttgc tttgacttca agcctttaca cagaaatgtt
    15961 gaaaaatcct cgtgttatcg gtgttaagaa ctcttcaatg ccagttcaag atatccaaac
    16021 ctttgtcagc cttggcgggg aagaccatat tgtctttaac ggtccagatg aacagttcct
    16081 aggtggccgc ctcatgggtg ctaaggctgg tatcggtggt acttatggtg ctatgccaga
    16141 actcttcttg aaactcaatc agttgattgc ggataaagat ttagaaacag cgcgtgaatt
    16201 gcagtatgct atcaacgcaa tcattggtaa actcactgct gcacatggaa atatgtacgg
    16261 tgtcatcaaa gaagttttga agatcaatga aggcttgaat attggttctg ttcgttcacc
    16321 attgacacca gtgactgaag acgatcgtcc agttgtagaa gcggctgcag ccttgattcg
    16381 tgaaaccaag gagcgcttcc tctaatctaa aaggaggtat ttatgacata ctacgttgca
    16441 attgatatcg gtggaactaa catcaagtat ggtttggttg atcaagaggg gcaacttctt
    16501 gaatcacatg aaatgccaac agaggcgcat aagggtggac ctcatatctt acaaaagacc
    16561 aaagatatcg tagctagtta tttagaaaaa ggcccagtag caggtgttgc catatcttct
    16621 gctgggatgg tggatccgga taagggtgag attttctatg ctgggccgca aatccctaac
    16681 tacgcaggca cccagttcaa aaaggaaatc gaagaaagct ttactattcc ttgtgagatt
    16741 gaaaatgatg tcaactgtgc aggtcttgct gaggcagtat ctggttcagg caagggagca
    16801 agtgtgacac tttgcttgac cattggaacc ggtatcggtg gttgcttgat tatggatagg
    16861 aaagtcttcc atggttttag taattcagcc tgtgaagtcg ggtatatgca tatgcaggat
    16921 ggagcttttc aggatctcgc ttctacaaca gctttagtga aatatgtagc tgaagcccat
    16981 ggagaagatg ttgatcagtg gaatggccga cgtatcttta aggaagctac tgaaggaaac
    17041 aaaatctgca tggaaggtat tgaccgtatg gttgactatc taggaaaagg tctggcaaat
    17101 atttgctacg ttgccaatcc agaagtggtc attcttggtg gtggtatcat ggggcaagag
    17161 gctatcctca aacctaagat ccgcacagcc ttgaaagagg ctttggtacc aagtttagca
    17221 gaaaaaacac gattagaatt tgcccatcac caaaatacag cagggatgtt gggtgcatat
    17281 tatcatttta agacaaaaca atcctagttt ggctcagcca aactaggatt ttcttacacg
    17341 tttttgtcta cgatagccgt tgagtttttt attttcccag tagctattaa agattttttc
    17401 cttgctttcg cgattgattt ccaaaaagta ggcataaatc aaatcgataa agaagagcat
    17461 aggaagttga gcggatattc gttggatata ggagggttgg ctgtgggtgg ctacaagaac
    17521 agtctctgta taggtctggc tatttttatt gggaacactt gtaaagagta cagtctttgc
    17581 ccccatctcc ttggcatcta atagactatc taaaatagaa ggagttgagc ctgaaagtga
    17641 gaagcccagt actagacaat tttcatccat gatgctggtt gtccaggcaa agccgtcttg
    17701 gtctgtcaaa gcttcgcaga ccacacctaa tcgcataaaa cgtaatttca tttcacgggc
    17761 gacgaggcca gaactccctg ttccaaagaa gtagatacgc tcagcatctt cgattagctg
    17821 ggcaattcgt tctagttgga tttcgtcaat caagtcttgt gtttgttccc tcatattgct
    17881 ataacttctg aggactcgtt tggtcagtgg actgtgcttg gaaacttggt tggcttgatt
    17941 ttctgcctga tgttggtatt ggaaaataaa ttctcggtag ccagtaaagc cacacttttt
    18001 agcaaagcgg gtcaaagcag cttgagaaat atgtaatttt tgggtgactt gttgagaaga
    18061 taaatcatct gtaatcgttt cagcttgcaa aaaatagcga gcgatttctt gctctaggtc
    18121 tgtcatttct tcaaaatgtg aatcaatgat agttgcgata tctggtttgt ccatagggaa
    18181 agctccttta catgagtcat actggaagac tagatcaggg aatagtcaca cttcattata
    18241 acacataata taaggataga taaataaaaa cgcatctctg ttttaaaaac gaaaaaatcg
    18301 aaaaagcttc tctcttttcc ataattttct actcaaattg tggtacaatt aagagtaaga
    18361 ttttaagtta gaaatgagac tgatttgtat gagaaaattt aacagccatt cgattccgat
    18421 tcggcttaat ttattgtttt caatcgtcat tttactcttt atgaccatta ttggtcgttt
    18481 gttgtatatg caggttttga acaaggattt ttacgaaaaa aagctagcct cagctagtca
    18541 gaccaagatt acaagcagtt cagcccgtgg ggaaatttat gatgctagtg gaaaaccttt
    18601 ggtagaaaat acgttaaagc aggttgtttc ctttacgcgt agcaataaaa tgacggctac
    18661 agacttaaaa gaaacagcta aaaagttact gacttatgtg agcatcagtt ctccaaattt
    18721 gacagaacgc cagctggcgg attactattt ggctgatcct gaaatctata aaaaaatagt
    18781 ggaagctctc ccaagcgaga aacgcttgga ttcagatggc aatcgtctat ccgaatcaga
    18841 actgtataac aatgcggtcg atagtgtaca aacgagtcaa ctaaactata cagaggatga
    18901 aaagaaagaa atctatcttt ttagtcagtt aaatgctgtt ggaaactttg cgacaggaac
    18961 cattgctaca gatcctctaa atgattctca ggtggctgtt attgcctcta tttcaaagga
    19021 gatgcctggc attagtattt ctacttcttg ggatagaaag gttttggaaa cttccctttc
    19081 ttctatagtt gggagtgtat ccagtgaaaa agctggtctc ccagcggaag aagcagaagc
    19141 ctatcttaaa aaaggctatt ctctaaatga tcgtgtagga acctcctatt tggaaaagca
    19201 atatgaagag accttacaag gaaaacgctc ggtaaaagaa atccatctgg ataaatatgg
    19261 caatatggaa agcgtggata caattgagga aggtagtaag ggaaacaata tcaaactgac
    19321 cattgatttg gctttccaag atagcgtgga tgctttactg aaaagttatt tcaattctga
    19381 gctagaaaat ggtggagcca agtattctga aggtgtctat gcagtcgccc ttaacccaaa
    19441 aacaggtgcg gttttgtcta tgtcagggat taaacatgac ttgaaaacgg gagagttgac
    19501 gcctgattcc ttgggaacgg taaccaatgt ctttgttcca ggttcggttg tcaaggcggc
    19561 gaccatcagc tcaggttggg aaaatggagt cttgtcagga aaccagacct tgacagacca
    19621 gtccattgtc ttccaaggtt cagctcccat caattcttgg tatactcagg cttacggttc
    19681 attccctatc acagcggtcc aagctctgga gtattcatca aatacctata tggtccaaac
    19741 agccttaggt cttatggggc aaacctatca acccaatatg tttgtcggca ccagcaatct
    19801 agagtctgct atggagaaac tgcgttcaac ctttggcgaa tatggcttgg gtactgcgac
    19861 aggaattgac ctaccagatg aatctactgg atttgttccc aaagagtata gctttgctaa
    19921 ttacattact aatgcctttg ggcagtttga taactatacg ccgatgcagt tggctcagta
    19981 tgtagcaact attgcaaata atggtgttcg tgtggctcct cgtattgttg aaggcattta
    20041 tggtaataat gataagggag gactgggtga cttgattcag caactgcaac cgacagagat
    20101 gaataaggtc aatatatccg actccgatat gagcatcttg caccaaggtt tttatcaggt
    20161 tgcccatggt actagtggat tgacaactgg acgtgccttt tcaaatggtg ccttggtatc
    20221 cattagcgga aaaacaggta cagccgaaag ctatgtggca gatggtcagc aagcaaccaa
    20281 taccaatgcg gtggcctatg ccccatctga taatccccaa atcgctgtcg cagtggtctt
    20341 tcctcataat accaatctaa caaatggtgt aggaccttcc attgcgcgtg acattatcaa
    20401 tctgtatcaa aaataccatc caatgaacta gaaaggaaat tatgctttat ccaacaccta
    20461 ttgccaagtt gattgacagt tattctaagt taccaggtat cgggattaag acggctacgc
    20521 gtctggcctt ttatacgatt gggatgtctg ctgatgatgt caatgaattt gcaaaaaatc
    20581 tcctttctgc taagagagaa ttgacatatt gttctatttg tggacgtttg acagacgacg
    20641 atccttgttc tatctgtact gattcgactc gtgaccagac aacaatttta gttcttgagg
    20701 atagtagaga tgtggcagcc atggaaaata tccaagaata ccatggactc tatcatgtcc
    20761 tgcatggcct catttctcct atgaatggta tcagtccgga cgatatcaat cttaagagcc
    20821 ttatgactcg tcttatggat agtgaggttt cagaagtgat tgtggcgact aatgctacag
    20881 cggatggtga agcgacctcc atgtatcttt cacgtttgct caagccggct ggtatcaagg
    20941 ttacgcgtct agcacgaggt ctcgctgtgg gagcggacat tgagtatgcg gacgaagtga
    21001 cactcttacg agcgattgaa aatcggacag agttgtaagt gtaggcaaat ttacgaactc
    21061 cattcattta taaaaaatca aagaggctga aaatcgttcc tatcggcctc tttttgtata
    21121 gtgtgatgag tagaatcagg ttcaagtttt aaaaaaccaa gcaaatatga tatactaaag
    21181 agcgagtatt ctagtagaat taggacaaat aatatgaaac aaacgattat tcttttatat
    21241 ggtggacgga gtgcggaacg cgaagtctct gtcctttcag ctgagagtgt catgcgtgcg
    21301 gtcaattacg accgtttcac agtcaagact ttctttatca gtcagtcagg tgactctatc
    21361 aaaacgcagg aatttagtca tgctccgggg caagaagacc gtctcatgac caatgaaacc
    21421 attgattggg ataagaaagt tgcaccaagt gctatctacg aagaaggtgc agtggtcttt
    21481 ccagtccttc acgggccaat gggagaagat ggctctgttc aaggattctt ggaagttttg
    21541 aaaatgcctt acgttggttg caacattttg tcatcaagtc ttgccatgga taaaatcacg
    21601 actaagcgtg ttctggaatc tgctggtatt gcccaagttc cttatgtggc tatcgttgaa
    21661 ggcgatgatg tgactgctaa aatagctgaa gtggaagaaa aattggctta tccagtcttc
    21721 actaagccgt caaacatggg gtctagtgtc ggtatttcta agtctgaaaa ccaagaagaa
    21781 ctccgtcaag ccttaaaact tgccttccga tatgacagcc gtgtcttggt tgagcaagga
    21841 gtgaatgccc gtgaaattga ggttggcctc ttgggtaact acgatgtcaa gagcacgcta
    21901 cctggagaag ttgtcaagga cgttgccttt tatgactacg atgccaagta tattgataac
    21961 aaggttacta tggatattcc tgccaaaatc agtgatgatg tggtggctgt catgcgtcaa
    22021 aatgcagaaa cagccttccg tgccattggt ggccttggtc tatctcgttg cgatttcttc
    22081 tatacagata agggagagat ttttctcaac gagctcaata ccatgccagg tttcacccag
    22141 tggtctatgt acccactact ttgggaaaat atggggatca gctacccaga actaatcgag
    22201 cgtttggttg accttgccaa ggaaagtttt gacaagcgcg aagcgcattt gatataaaat
    22261 gaaagagagg gtagaagcca gaaccatcac tgcaaggtga ctagagttct cggacttcag
    22321 ccctttttaa aggagtagaa atgaaattaa caatccatga aattgcccaa gttgttggag
    22381 ccaaaaatga tatcagtatc tttgaggaca ctcagttaga aaaagctgag tttgatagtc
    22441 gtttgattgg aactggagat ttatttgtgc cacttaaagg tgcgcgtgat ggccatgact
    22501 ttattgaaac agcctttgaa aatggtgcag cagtaacctt gtctgagaaa gaggtctcaa
    22561 atcatcctta cattttagta gatgatgttt tgacagcctt tcaatcccta gcatcctact
    22621 atcttgaaaa aacgactgtt gatgtctttg ctgttacagg ttcaaatggc aagacaacga
    22681 ctaaggatat gttggcgcat ttactgtcaa caagatacaa gacctacaaa acacaaggca
    22741 attacaataa tgagattggc cttccttaca cagttcttca tatgcctgaa ggaacagaaa
    22801 agttggtttt ggagatggga caggatcact tgggagatat tcatctcttg tctgaattgg
    22861 ctcgtccaaa aacagccatc gtgaccttgg ttggagaagc tcatttggcc tttttcaaag
    22921 atcgttctga gattgctaaa ggaaaaatgc aaattgcaga cggaatggct tcaggttcct
    22981 tgcttttagc gccggctgac cctatcgtag aggactattt gccaattgat aaaaaggtgg
    23041 ttcgttttgg tcaaggagca gagctggaaa ttactgactt ggttgagcgt aaggacagtc
    23101 tgacctttaa ggctaatttc ttggaacaag cccttgattt gccagtaact ggcaagtaca
    23161 atgcgacaaa tgctatgatt gcatcctatg ttgccttgca agaaggagtt tcagaggagc
    23221 aaattcgttt ggcattccaa catcttgaat tgacgcgtaa ccgtaccgag tggaagaaag
    23281 cagccaatgg agcagatatc ctgtcagatg tttacaatgc caatccaact gctatgaaac
    23341 tgattttaga gactttctct gccattccag ccaatgaagg tggcaagaaa attgcagtgt
    23401 tggcggatat gaaggagctt ggtgaccagt ctgttcaact tcataatcag atgattttga
    23461 gcctctcccc agatgtgctt gatatcgtta ttttctatgg agaagatatt gctcagttgg
    23521 ctcaattggc cagtcaaatg tttccaatcg gccacgttta ctacttcaag aaaacagaag
    23581 accaggatca atttgaagac ctagtcaagc aggttaagga aagccttgga gcctatgacc
    23641 aaatcttgct aaaaggttct aactctatga atctagccaa attggtagaa agtttagaaa
    23701 atgaatgcaa gtgattttgc taagtatctt caaagaatga ttgctcttac agatactgga
    23761 ctaaccttta caaaggatcc gtttgaccgt gagcgctacg aagacttgcg aagtctgtta
    23821 tctgaaatgt tgaatcaggt atcagacctt gatgcagacg aagtggcaga actcttgaaa
    23881 ccgacctccg cttatgcgac tcctttaatg gacgtccgtg cttggatagt tgaggatgaa
    23941 aaaatttgtc tggttagggg acaaggagag aatgattggg ctttgccagg tggctttggc
    24001 gaggtcggtt attcaccaac tgaaaatatt ctcaaggaaa ttgaagaaga aaccggtttt
    24061 aaagccaaag ttgaacgact actagctgtt tttgatacca atcgtttcca actacagagc
    24121 aaacaatatg caaagtttgt ttttgaatgt aagcttctcg atggacaatt tcaagaaaat
    24181 caagaaatcg ctgaccttca attttttgca attgaccaac tgccgaattt atctgaaaaa
    24241 cgcattacca aggagcaaat agagcttctt tggcaggttt atcaaggtca tagggggcaa
    24301 tatcttgact aagaagatga ttatcgtatt tctaaatcca tttttaacaa ctagcatggt
    24361 ataataatat gcaggaaaat tttgaattat gaggaagact agatgaattt atgggatatt
    24421 ttctttacga ctcaggcaac cgagccgccc aaatttgacc ttttttggta tgttagccta
    24481 tttacgctct tagccttaac cttttataca gcccatcgct atcgtgaaaa taaggtttac
    24541 caacgatttt tccaaatctt gcagactgtt cagttaatcc ttctttatgg ttggtactgg
    24601 gtcaatcata tgccactgtc agaaagccta cccttttacc attgccgtat ggctatgttt
    24661 gtggtactct tgcttcctgg tcaatccaaa tataaacaat actttgcatt attgggaaca
    24721 tttgggacat tagcagcctt tgtttatcca gtgccagatg cttacccttt tccacatatc
    24781 accattctat cctttatctt tggtcattta gcactcttgg ggaactctct agtttatcta
    24841 ttgagacagt ataatgcgcg attgctggat gtgaagggaa tttttctcat gacctttgcc
    24901 ctaaatgcct tgatttttgt ggtcaatttg gtgacaggtg gcgattacgg atttttgaca
    24961 aaaccgccat tggttgggga tcacggtcta gtagctaatt atttacttgt ttcaattgtg
    25021 ctggtagcta ctatcagttt gactaagaaa atcttagaat tctttttagc tcaagaagca
    25081 gaaaaaatga ttgcaaagga agcttaacac agagctttct tttttgctct tagagagttt
    25141 ttacaagcag cttataaaat aagaatttct gaatagacaa actcaaaaaa tggctgggaa
    25201 atttaggaaa aaagcaagca cgattaaatt ttttgtgtta taatattttg tgaatagcta
    25261 tgcctatgtt tagctatgga ataatacgaa gtgcgaaact tggaagatag agaggaagcg
    25321 atgtaatggc tagagaaggc ttttttacag gtctagatat tggaacaagc tctgtcaagg
    25381 tgcttgtggc cgagcagaga aatggtgaat taaatgtaat tggcgtgagt aatgccaaaa
    25441 gtaaaggtgt aaaggatgga attattgttg atattgatgc agcagcaact gctatcaagt
    25501 cagccatttc ccaagcggaa gaaaaggcag gcatttcgat taaatcagtg aatgtcggct
    25561 tgcctggtaa tcttttgcag gtagaaccaa ctcaggggat gattccagta acatctgata
    25621 ctaaggaaat tacggatcaa gatgttgaaa atgttgtcaa atcagctttg acaaagagta
    25681 tgacacctga ccgtgaagtc attaccttta ttcctgaaga atttattgtg gatggtttcc
    25741 aagggattcg tgacccacgt ggcatgatgg gggttcgcct tgaaatgcgt ggtttgcttt
    25801 atacaggacc tcgtactatc ttgcacaatt tgcgtaagac ggttgagcgt gcaggtgttc
    25861 aggttgaaaa tgttatcatt tcaccactag caatggttca gtctgttttg aacgaagggg
    25921 aacgtgaatt tggtgctaca gtgattgata tgggggcagg tcaaacgact gtcgctacaa
    25981 tccgtaatca agaactccag ttcacacata ttctccaaga aggtggagat tatgtaacta
    26041 aagatatctc caaggttttg aaaacctctc gcaaattagc ggaaggctta aaactgaatt
    26101 acggggaagc ctatccgcct cttgcaagca aagaaacctt ccaagtagag gttattggag
    26161 aagtagaagc agtcgaagtg acggaagcct acttgtcaga aattatttct gcacgaatca
    26221 agcacatcct tgaacaaatc aagcaagaat tagatagaag gcgtctattg gacctccctg
    26281 gtggtattgt cttaatcggt gggaatgcca ttttaccagg tatggttgag cttgctcagg
    26341 aagtctttgg cgtccgtgtc aagctttatg ttccaaatca agttggtatc cgtaatccag
    26401 cctttgcgca tgtgattagt ttatcagaat ttgcgggtca attaacagaa gttaatcttt
    26461 tggctcaggg agcgataaaa ggtgagaatg acttaagtca tcagccaatt agttttggtg
    26521 ggatgctgca aaaaacagct cagtttgtac aatcaacgcc tgttcaacca gctcctgctc
    26581 cagaagtaga gccggtggcg cctacagaac caatggcgga tttccaacaa gcttcacaaa
    26641 ataaaccgaa attagcagat cgtttccgtg gcttgatcgg aagcatgttt gacgaataaa
    26701 gaggaaaaat aaattatgac attttcattt gatacagctg ctgctcaagg ggcagtgatt
    26761 aaagtaattg gtgtcggtgg aggtggtggc aatgccatca accgtatggt cgacgaaggt
    26821 gttacaggcg tagaatttat cgcagcaaac acagatgtac aagcattgag tagtacaaaa
    26881 gctgagactg ttattcagtt gggacctaaa ttgactcgtg gtttgggtgc aggaggtcaa
    26941 cctgaggttg gtcgtaaagc cgctgaagaa agcgaagaaa cactgacgga agctattagt
    27001 ggtgccgata tggtcttcat cactgctggt atgggaggag gctctggaac tggagctgct
    27061 cctgttattg ctcgtatcgc caaagattta ggtgcgctta cagttggtgt tgtaacacgt
    27121 ccctttggtt ttgaaggaag taagcgtgga caatttgctg tagaaggaat caatcaactt
    27181 cgtgagcatg tagacactct attgattatc tcaaacaaca atttgcttga aattgttgat
    27241 aagaaaacac cgcttttgga ggctcttagc gaagcggata acgttcttcg tcaaggtgtt
    27301 caagggatta ccgatttgat taccaatcca ggattgatta accttgactt tgccgatgtg
    27361 aaaacggtaa tggcaaacaa agggaatgct cttatgggta ttggtatcgg tagtggagaa
    27421 gaacgtgtgg tagaagcggc acgtaaggca atctattcac cacttcttga aacaactatt
    27481 gacggtgctg aggatgttat cgtcaacgtt actggtggtc ttgacttaac cttgattgag
    27541 gcagaagagg cttcacaaat tgtgaaccag gcagcaggtc aaggagtgaa catctggctc
    27601 ggtacttcaa ttgatgaaag tatgcgtgat gaaattcgtg taacagttgt cgcaacgggt
    27661 gttcgtcaag accgcgtaga aaaggttgtg gctccacaag ctagatctgc tactaactac
    27721 cgtgagacag tgaaaccagc tcattcacat ggctttgatc gtcattttga tatggcagaa
    27781 acagttgaat tgccaaaaca aaatccacgt cgtttggaac caactcaggc atctgctttt
    27841 ggtgattggg atcttcgccg tgaatcgatt gttcgtacaa cagattcagt cgtttctcca
    27901 gtcgagcgct ttgaagcccc aatttcacaa gatgaagatg aattggatac acctccattt
    27961 ttcaaaaatc gttaagtaaa tgaatgtaaa agaaaataca gaacttgttt ttcgagaagt
    28021 tgcagaggct agtctgagtg ctcatcgaga gagtggttcg gtctctgtca ttgcagttac
    28081 caagtatgta gatgtaccga cagcggaagc cttgcttccg ctaggtgttc atcatatcgg
    28141 tgaaaatcgt gtagataagt ttctggaaaa atatgaagct ttaaaagatc gagatgtgac
    28201 ttggcatttg attggtacct tgcaaagacg taaggtgaaa gatgtcattc aatacgttga
    28261 ttatttccat gcattggact cagtaaagct agcaggggaa attcaaaaaa gaagtgaccg
    28321 agtcatcaag tgtttccttc aagtaaatat ttctaaagaa gaaagcaaac acggtttttc
    28381 gagagaggaa ctgctggaaa tcttgccaga gttagccaga ctagataaga ttgaatatgt
    28441 tggtttaatg acgatggcac cttttgaggc tagcagtgag cagttgaaag agattttcaa
    28501 ggcggcccaa gatttacaaa gagaaattca agagaaacaa attccaaata tgcctatgac
    28561 cgagttaagt atgggaatga gtcgtgatta taaagaagcg attcaattcg gttccacttt
    28621 tgttcgtata ggtacatcat tttttaagta ggagagaacc atgtctttaa aagatagatt
    28681 cgatagattt atagattatt ttacggagga tgaggattca agtctccctt atgaaaaaag
    28741 agatgagcct gtgtttactc cagtaaattc ttcacaggaa ccggctctcc caatgaatca
    28801 accttcacag tcggctggta caaaagagaa caatatcacc agacttcatg caagacaaca
    28861 ggaattggca aatcagagtc agcgtgcaac ggataaggtc attatagatg ttcgttatcc
    28921 tagaaaatat gaggatgcaa cagaaattgt tgatttattg gcaggaaacg aaagtatctt
    28981 gattgatttt cagtatatga cagaggtgca ggctcgtcgt tgtttggact atttggatgg
    29041 agcttgtcat gttttagctg gaaatttgaa aaaggtagct tctaccatgt atttgttgac
    29101 accagttaat gttattgtaa atgttgaaga tatccgttta ccagatgaag atcaacaggg
    29161 tgagttcggt tttgatatga agcgaaatag agtacgataa tgattttttt aattcgtatg
    29221 atttataatg cagtggatat ttactccctg attttggtag ccttcgctgt catgtcttgg
    29281 tttccaggtg cctacgaatc cagtttaggt cgttggattg tagcgttggt gaaaccagta
    29341 cttgctccct tgcaacgcct gcctttacag atagcgggtc ttgatttatc tgtttgggtc
    29401 gcgattgttt tggttcgatt tttaggagaa aacctagtgc gttttctggc gatgatagga
    29461 tgaataaagg gatttatcag catttctcca tagaagatcg tccatttctt gacaagggaa
    29521 tggaatggat aaagaaggta gaagatagct atgctccttt tttaactcct tttatcaatc
    29581 ctcatcagga gaagctatta aagattttgg ccaaaaccta tggtcttgct tgtagcagta
    29641 gtggggaatt cgtctcgagt gagtatgttc gagttttatt atacccagat tatttccaac
    29701 cagagttttc agattttgaa atatctctcc aagaaattgt gtattccaat aaatttgaac
    29761 atttaacgca tgctaagatt ttagggacag tcatcaatca attagggatt gaacggaaac
    29821 tttttggaga tatcctagta gatgaagaac gggcgcagat tatgattaat cagcagtttc
    29881 ttcttctctt tcaagatgga ctaaagaaaa ttggtcgtat acctgtttcg ctggaggaac
    29941 gtcctttcac cgagaaaata gataagctag aacagtatcg agaactggat ttatctgtgt
    30001 ctagttttcg attagatgtt cttttatcaa atgttttgaa actatctagg aatcaagcaa
    30061 accagttgat tgaaaagaaa cttgtccaag taaattatca tgtggtagac aaatcagatt
    30121 acactgttca agttggagac ttgattagtg tgagaaaatt tggtcgcttg agattacttc
    30181 aagataaggg acaaacgaaa aaagagaaga aaaaaataac cgtccagtta ttattaagta
    30241 agtgaggaat agaatgccaa ttacatcatt agaaataaag gacaagactt ttggaactcg
    30301 attcagaggt tttgatccag aagaagtcga tgaattttta gatattgtgg ttcgtgatta
    30361 cgaagatctt gtgcgtgcga atcatgataa aaatttgcgt attaagagtt tagaagagcg
    30421 tttgtcttac tttgatgaaa taaaagattc attgagccag tctgtattga ttgctcagga
    30481 tacagctgag agagtgaaac aggcggcgca tgaacgttca aacaatatca ttcatcaagc
    30541 agagcaagat gcgcaacgct tgttggaaga agctaaatat aaggcaaacg agattcttcg
    30601 tcaagcaact gataatgcta agaaagtcgc tgttgaaaca gaagaattga agaacaagag
    30661 ccgtgtcttc caccaacgtc tcaaatctac aattgagagt cagttggcta ttgttgaatc
    30721 ttcagattgg gaagatattc tccgtccaac agctacttat cttcaaacta gtgatgaagc
    30781 ctttaaagaa gtggttagcg aagtacttgg agaaccgatt ccagctccaa ttgaagaaga
    30841 accaattgat atgacacgtc agttctctca agcagaaatg gaagaattac aagctcgtat
    30901 tgaggtagcc gataaagaat tgtctgaatt tgaagctcag attaaacagg aagtggaaac
    30961 tccaactcct gtagtgagtc ctcaagttga agaagagcct ctgctcatcc agttggccca
    31021 atgtatgaag aaccagaagt agctccagtg catccgacag gtccaacacc agctacagaa
    31081 actgttgatt cagcaccagg atttgaagca ccgcaagaat ccgttacaat tttataagaa
    31141 acgatgtgag aacaatatct tatccttata tttccagcga gcaggagatg gtgtgagtcc
    31201 tgcattccct aacgataaga ttatcctctc aaaaactcaa gtctgaagct agtaagattt
    31261 gacgtttccc acgttacggg ataagaggga gaaagactaa atctttttcc gaataaaggt
    31321 ggtaccacga ttttcgtcct ttttggaagt cgtggttttt aatttgttat tatttataaa
    31381 ggagatacca tgaaactcaa agataccctt aatcttggga aaacagcttt cccaatgcgt
    31441 gcaggccttc cgaccaaaga gccagtttgg caaaaggaat gggaagatgc aaaactttac
    31501 caacgtcgtc aagaactaaa tgaagggaaa ccgcattttg tcttgcatga tggccctcca
    31561 tacgcaaacg gaaatatcca cgttggacat gccatgaatc atatctcaaa agatatcatc
    31621 attcgttcta agtctatgtc aggttttaac gcaccttata tcccaggttg ggatactcat
    31681 ggtctgccaa tcgagcaagt tttggcaaag caaggtgtga agcgcaaaga aatggacttg
    31741 gttgagtact tgaaactctg tcgtgagtac gctctttctc aagtttataa acaacgtgat
    31801 gatttcaaac gcttggggat gtcaggtgac tgggaaaatt tatatgtgac tttaactcca
    31861 gactatgaag cagcccaaat ccgtgtcttt ggtgagatgg ctaataaggg ttatatctac
    31921 cgtggtgcca agccagttta ctggtcatgg tcatctgagt cagcccttgc cgaagcggaa
    31981 attgaatacc atgatttggt ttcgacttca ctttattatg ccaataaggt aaaagatggc
    32041 aaaggtatcc tagatacaga tacttatatc gtagtctgga caacaactcc atttaccatc
    32101 acagcttctc gtggtttgac tgttggtgca gatattgatt acgttttggt tcaacctgct
    32161 agtgaaactc gtaagtttgt cgttgctgca gaattgttga ctagcttgtc tgagaaattt
    32221 ggctgggctg atgttcaagt gttggcaact taccgtggtc aagaactcaa ccacatcgta
    32281 acagaacacc catgggatac agctgtagat gagttggtaa tccttggtga tcacgttacc
    32341 actgactctg gtacaggtat cgtccataca gcccctggtt ttggtgagga cgactacaat
    32401 gttggtattg ctaatggtct tgaagtcgca gtgactgttg acgaacgcgg tatcatgatg
    32461 gcgaatgctg gtcctgagtt tgaaggtcag ttctacgaca aggttgtacc aactgttatt
    32521 gaaaaacttg gtaacctcct tctagcccaa gaagaaatct ctcactcata cccatttgac
    32581 tggcgtacta agaaaccaat catctggcgt gcagttccac aatggtttgc ctcagtttca
    32641 aaattccgcc aagaaatctt ggatgctatt gataaagtta aattccatac agaatggggt
    32701 aaagtacgtc tatataatat gattcgtgac cgtggtgact gggttatctc tcgtcaacgt
    32761 gcttggggtg ttccacttcc aatcttctat gcagaagacg gtacagctat catgacagct
    32821 gagactattg aacatgtggc gcaactcttt gaagtacatg gttcaagcat ttggtgggaa
    32881 cgtgatgcca aagacctctt accagaagga tttacacatc caggttctcc aaatggggag
    32941 ttcaagaaag aaacagatat tatggatgta tggtttgact caggttcatc atggaatggt
    33001 gttttggtaa atcgtcccaa tctgacttat ccagctgacc tttaccttga aggttctgac
    33061 caataccgtg gttggttcaa ctcatcactc attacatctg ttgccaacca tggcgtagca
    33121 ccttacaaac aaatcttgtc acaaggtttt acccttgatg gtaaaggtga gaagatgtct
    33181 aaatcacttg gaaataccat tgctccaagt gatgttgaaa aacaatttgg tgcagaaatc
    33241 ttgcgtctct gggtaacaag tgttgactca agcaatgacg tgcgtatctc tatggatatt
    33301 ttgagccaag tttctgaaac ttaccgtaag attcgtaaca ctcttcgttt cttgattgcc
    33361 aatacatctg actttaaccc agctcaagat gtagtcgctt acgatgaact tcgttcagtt
    33421 gataagtaca tgactattcg ctttaaccag cttgtcaaga ccattcgtga tgcctatgcg
    33481 gactttgaat tcttgacaat ctacaaggcc ttggtgaact ttatcaacgt tgacttgtca
    33541 gccttctacc ttgattttgc caaagatgtt gtttacattg aaggtgccaa atcattggaa
    33601 cgccgtcaaa tgcagactgt tttctatgac attcttgtca aaatcaccaa actcttgaca
    33661 ccaatccttc ctcacactgc ggaagaaatc tggtcatatc ttgagtttga agctgaagac
    33721 ttcgttcaat tgtcagaatt gccagaagct caaacttttg ctaatcaaga agaagtcttg
    33781 gatacatggg cagccttcat ggacttccgt ggacaagctc aaaaagcctt ggaagaagct
    33841 cgtaatgcaa aagttatcgg gaaatcgctt gaagcacact tgacagttta tccaaatgaa
    33901 gttgtgaaaa ctctactcga agcagtaaac agcaatgtgg ctcaactttt gatcgtgtca
    33961 gacttgacca tcgcagaagg gccagctcca gaagctgccc ttagcttcga agatgtagcc
    34021 ttcacagttg aacgcgctgc aggtcaagta tgtgaccgtt gccgtcgtat cgacccaaca
    34081 acagcagaac gcagctacca ggcagtcatc tgtgaccact gtgcaagcat cgtagaagaa
    34141 aactttgcgg aagcagtcgc agaaggattt gaagagaaat aaggttgaaa agtctaggca
    34201 aaattcaatt tgagaagaaa agacaactaa ttttatagtc tattaaacgc attgtatcac
    34261 gtttttgaat acctgatatg atgcgttttt tatttatttt aaaaatttgc gaggtatgac
    34321 tttttatact caacaagaat caaagagaaa cttagcaagc taacagtagt aagataaaat
    34381 aggaatttga tattagggat aagattgcta aatagtgtaa tatttttaca ataataaatt
    34441 tatatagtta tttttggttt ctgaaaagta ttatatttta tttcatat
//
LOCUS       DAVLAQ010000022        33665 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000022 DAVLAQ010000000
VERSION     DAVLAQ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.022"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(224..442)
                     /locus_tag="VXB71_001020"
     CDS             complement(224..442)
                     /locus_tag="VXB71_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0451149.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            600..746
                     /locus_tag="VXB71_001021"
     CDS             600..746
                     /locus_tag="VXB71_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451150.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FKEY"
     gene            complement(1338..2027)
                     /gene="rplA"
                     /locus_tag="VXB71_001022"
     CDS             complement(1338..2027)
                     /gene="rplA"
                     /locus_tag="VXB71_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0451151.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2235..2660)
                     /gene="rplK"
                     /locus_tag="VXB71_001023"
     CDS             complement(2235..2660)
                     /gene="rplK"
                     /locus_tag="VXB71_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0451152.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2783..3499)
                     /locus_tag="VXB71_001024"
     CDS             complement(2783..3499)
                     /locus_tag="VXB71_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0451153.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3517..3978)
                     /locus_tag="VXB71_001025"
     CDS             complement(3517..3978)
                     /locus_tag="VXB71_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0451154.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3980..5017)
                     /locus_tag="VXB71_001026"
     CDS             complement(3980..5017)
                     /locus_tag="VXB71_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0451155.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(5115..6440)
                     /gene="brnQ"
                     /locus_tag="VXB71_001027"
     CDS             complement(5115..6440)
                     /gene="brnQ"
                     /locus_tag="VXB71_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0451156.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6611..6703)
                     /locus_tag="VXB71_001028"
     CDS             complement(6611..6703)
                     /locus_tag="VXB71_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0451157.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6746..6898)
                     /locus_tag="VXB71_001029"
     CDS             complement(6746..6898)
                     /locus_tag="VXB71_001029"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0451158.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(7058..7636)
                     /locus_tag="VXB71_001030"
     CDS             complement(7058..7636)
                     /locus_tag="VXB71_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0451159.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7690..9090)
                     /gene="pepV"
                     /locus_tag="VXB71_001031"
     CDS             complement(7690..9090)
                     /gene="pepV"
                     /locus_tag="VXB71_001031"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0451160.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9103..9708)
                     /locus_tag="VXB71_001032"
     CDS             complement(9103..9708)
                     /locus_tag="VXB71_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0451161.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9879..10679
                     /locus_tag="VXB71_001033"
     CDS             9879..10679
                     /locus_tag="VXB71_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0451162.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10863..11696)
                     /locus_tag="VXB71_001034"
                     /pseudo
     CDS             complement(10863..11696)
                     /locus_tag="VXB71_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(11686..13533)
                     /gene="uvrC"
                     /locus_tag="VXB71_001035"
     CDS             complement(11686..13533)
                     /gene="uvrC"
                     /locus_tag="VXB71_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0451163.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGSIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(13573..14274)
                     /locus_tag="VXB71_001036"
     CDS             complement(13573..14274)
                     /locus_tag="VXB71_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0451164.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLAGQ
                     FLSVTVRLNHYYLSNPHYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14353..15585)
                     /gene="murN"
                     /locus_tag="VXB71_001037"
     CDS             complement(14353..15585)
                     /gene="murN"
                     /locus_tag="VXB71_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0451165.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEYFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15590..16810)
                     /gene="murM"
                     /locus_tag="VXB71_001038"
     CDS             complement(15590..16810)
                     /gene="murM"
                     /locus_tag="VXB71_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0451166.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16922..17701)
                     /locus_tag="VXB71_001039"
     CDS             complement(16922..17701)
                     /locus_tag="VXB71_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0451167.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17770..19431)
                     /locus_tag="VXB71_001040"
     CDS             complement(17770..19431)
                     /locus_tag="VXB71_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0451168.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19606..21828)
                     /gene="recJ"
                     /locus_tag="VXB71_001041"
     CDS             complement(19606..21828)
                     /gene="recJ"
                     /locus_tag="VXB71_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0451169.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GGASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22105..22908
                     /locus_tag="VXB71_001042"
     CDS             22105..22908
                     /locus_tag="VXB71_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0451170.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     EVADRIIFMADGEVLVDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22948..23712
                     /locus_tag="VXB71_001043"
     CDS             22948..23712
                     /locus_tag="VXB71_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0451171.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQGDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     EFNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23725..24402
                     /locus_tag="VXB71_001044"
     CDS             23725..24402
                     /locus_tag="VXB71_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0451172.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24412..25071
                     /locus_tag="VXB71_001045"
     CDS             24412..25071
                     /locus_tag="VXB71_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0451173.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNSVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25367..26557
                     /locus_tag="VXB71_001046"
     CDS             25367..26557
                     /locus_tag="VXB71_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0451174.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26878..27759)
                     /locus_tag="VXB71_001047"
     CDS             complement(26878..27759)
                     /locus_tag="VXB71_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0451175.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27900..29228)
                     /gene="vncS"
                     /locus_tag="VXB71_001048"
     CDS             complement(27900..29228)
                     /gene="vncS"
                     /locus_tag="VXB71_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0451176.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(29225..29881)
                     /gene="vncR"
                     /locus_tag="VXB71_001049"
     CDS             complement(29225..29881)
                     /gene="vncR"
                     /locus_tag="VXB71_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0451177.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29930..30013)
                     /gene="pep27"
                     /locus_tag="VXB71_001050"
     CDS             complement(29930..30013)
                     /gene="pep27"
                     /locus_tag="VXB71_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0451178.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(30193..31572)
                     /gene="vex3"
                     /locus_tag="VXB71_001051"
     CDS             complement(30193..31572)
                     /gene="vex3"
                     /locus_tag="VXB71_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0451179.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31624..32271)
                     /gene="vex2"
                     /locus_tag="VXB71_001052"
     CDS             complement(31624..32271)
                     /gene="vex2"
                     /locus_tag="VXB71_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0451180.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32284..33561)
                     /locus_tag="VXB71_001053"
     CDS             complement(32284..33561)
                     /locus_tag="VXB71_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451181.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGNSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9546 a         7688 c         6252 g        10179 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaaggc ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taatcaaatt
      121 ttattcaatc catctactca ttcccaaaaa gttgctgtat aatgcaagac atttttctta
      181 ctgcttttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactatt gaaacaatag aacgtaaata aggataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatggct ataatcatct gtatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaactgatt aggaaattta aaccaacttc taacaatgtg ttatactcaa
      601 tgaaaaccaa agagcaaact aggaaactag ccgcaggttg ctcaaaacac tgttttgagg
      661 ttgtggatag aactgacgaa gtcagtaacc atacgcacgg caaggcgacg ttgacgtggt
      721 ttgaagagat tttcaaagag tattagaaag ctcgatggac tattccagat tcattccact
      781 agatttcgaa atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt
      841 tcggcatacg gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca
      901 cgaaaccagt ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt
      961 ctgagctact atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta
     1021 gaaatcgatt tgactgtcct gaacgattcg tcctattctt atttcatttt attataattg
     1081 atagtggtcg ccccagccag ataccttatc cgctatatag gccttattat cacgttcctg
     1141 ttcgtagagc cacgatttcg ctatcccttc ctctgacgat tcttatttcc agcgtcagac
     1201 ttgggaatcg ctattgggtt caccggtagt aggtgcccac cgaggactta cacctcagat
     1261 atacgacatg cccgtcgtac atcaaaaaaa gttgagacat agtgtcttca acttttttac
     1321 attactttaa ctactgatta aagtgagttt acgtcaactt tgataccaac accttgagta
     1381 gttgtgatag tcaagtttgt tacgtaagtt cctttagctg tagctggttt tactttttgg
     1441 attgtttcgt tgaaagcttt aaagttttca accaattttt cagcttcaaa tgatacttta
     1501 ccgatgattg cttgaacgtt acctgcacgg tcagcacggt aagtgatttt accaccttta
     1561 gactcttcaa ctgctttagc aacatccatt gttacagtac cagttttagg gtttggcatc
     1621 aagttacgtg gtccaaggac acgtccaaga cgtccaacaa gagccatcat atcaggtgta
     1681 gcgataacta cgtcgaagtc caaccaaccg tcgttgattt tagcaacaag gtcatcttca
     1741 ccaacaaagt ctgcaccagc agcttttgct tcttcagctt ttgcaccacg tgcgaaaaca
     1801 agaacacgtg aagttttacc agtaccgttt ggcaatacca ttgctccacg gatttgttgg
     1861 tcagcttttt taacgtcgat gttcaagttg taagcaactt ctacagttgc atcaaatttt
     1921 gcaaagttag tttcttttgc aagtgctaca gcttcttcta cactgtatgc ttttgtgctg
     1981 tcgattttct caagagcagc acgaagttgt ttgctttttt tagccatttt ctattctcct
     2041 tgtaagtggt tcaatcgatt ttcatctccc acgtcacttc tcgaaatgat gaagtcttgc
     2101 gggttttcag tctactattt ttctcttcct acggccttaa gctcccttgc tgtatccaag
     2161 tacaagcctc agtcacttgc ctagtatgaa aagcaactaa tagactgctg tgagattttc
     2221 tactgtgtta ttgattagtc aacaacagtg aatcccatag aacgagcagt accttcgatc
     2281 atacgcattg cagactctac gtttgctgcg ttcaaatctg gcatcttagt ttctgcaatt
     2341 tcttgtactt gtgcacgagt aactgtagca actttagttt tattaggtgt acctgatcct
     2401 ttttcaacac ctgcagcttt tttcaaaaga acagcagctg gtggtgtttt cgtaacgaaa
     2461 gtaaatgatt tatcttcgta aactgagata acaactggaa tgatcatacc agcttggtca
     2521 gctgtacgag cgttgaactc ttttgtgaat cccatgatgt tgataccagc ttgaccaaga
     2581 gcaggtccaa ccggtggagc tggtgtagct ttaccagcag ggatttgcaa ttttacaagt
     2641 ttttcgactt ttttagccat ttttaaatcc tcctttgtgg ttttggcggt aattagagat
     2701 ttttacctcc cacaagtatg ctttacacat acctttccat tatacactat ttatctaaaa
     2761 atgcaagaga aaactttcat ttttaatcga cataatcgcc gccttcaaag ccatagtact
     2821 cttccaaact gagaccactt gcagcaattt ctttggcttc ttttccaacg tagcggagat
     2881 gccattcttc tgccatgtag ccagtctcct tttccttgcc tttaagatag cgaacaacaa
     2941 agccatagtc agccgcatgg tccaagagcc actgggctgc cttttcttca gtaactaaat
     3001 ccccatctgt cccaatcaaa tcaaaagcaa gacccgtctg gtgttcactg taacctgggc
     3061 gtgctgagta gcgatctgct gcttccttac catcttgatt gacatagtct tggtagagct
     3121 tagcctgagt ttcataactc ctaaacccac tgtattggtc actgattgga tagccctcag
     3181 cctgcatagc tgcgattagt ttgagcaact ctgccttggc tgttggattt tctcctggat
     3241 tgtaatcttt tgacaaagga taacgtttat tagctaggat aatctcatcg tatttccctt
     3301 ggatactata atagctccct ttattgctaa cttctgcctt tttctgacta gaagcttgag
     3361 atttgctacc tacagttcct tccggttgac tgctttgctc cgttttttga gtgttttctt
     3421 caactttggt tttttcttgc gaacaagctg caagggtcaa tgctagtaaa ccagataaaa
     3481 tgacatatct ttttttcatt tctttcttcc tctctcttag gccaaatact tctccaattc
     3541 atgagataag attttaatca tctcttccag ctctggcgat tgtacttggc aatcttctgc
     3601 cgccatttct tcccagggca cccaccagac tgggccacgg ccattcaaac cgtgactctt
     3661 catatcacct gctcttcggg gaaaaagatg ccaatgagcg tgggcatcgc catttcctag
     3721 gagttcaata ttcatctttt cagcctcaaa tgctttggcg actgcttctt ggactaaact
     3781 catttcctct aaaaagcgaa gttttacaga agtttccata tgatggagtt ctgtgacatg
     3841 atcttttgct aaaaataagg tatagccctt aaagtattgg tagtcaccaa taacaacata
     3901 gcctgtttct agttctttta caaagtaggg attttgccca gctttaatga gttcgattct
     3961 ctgacagatt aagcacattc tatgataccg cctcgctctt aagataagca tcaaccatac
     4021 gctcagtcgc tattactgaa tcgatgtggg tgcgctcata agagtgactg gactcaatac
     4081 cagctccaag aagtgcatgc ttgacctctg cacctgctga catcgctgct gaagcgtccg
     4141 atccgtaaaa tggatagatg tcgagcttaa atggaatatc ttgctcttta gccaaggcaa
     4201 ccaagtgttg acggaagtca tagtgataag gacctgaagc atccttgaca cagatagata
     4261 ctgtgtactc atctgtctgc tggtcatctc ccatagctcc catatccaca gccagatatt
     4321 ctactacctg agcaggaatg ttagaattag caccatgtcc tacttcttca aaaactgaaa
     4381 aagcaaaatg agttgttact ggcaattcaa tcttctcttt cttataaata cgaagcaggt
     4441 tgagcaaaat cgctgcgctg accttatcat ccaaatgacg agacttgata aaacctgtat
     4501 cagtcacaac agttcgtgta tcgaagctga taaaatcacc gacctcaatc ccaagagcac
     4561 gagtttcttt ttcattgctt acttttacat ccaaacgcac ttccatattg tcctgcgtgc
     4621 gttctgcagt tcctgcatcc ttgtagacat ggcaagaagt ttggtggatg aggatggttc
     4681 ctgatacctt ttgacctgtg ctagccacat gaacggtaca gttttcacct tcaatcatgt
     4741 tccaaggaaa accaccgata cggtccaatt taagacgacc atctggtttg acagcacgaa
     4801 caatagcacc cagcgtatcc acatgggcag tcacatagcg atgttgctca tcattttgac
     4861 ctttgatggt cacattgaca ccacccttag ctgtgcgaac tggctggtaa ccaaaacctt
     4921 ctagagtctt gactaaataa ttcgaaattt cacgagtgaa gcccgttggc gatgcgatgg
     4981 ctgtcagttc tttgatatat tctactgttt gattcatttc ttcacctctt tcgctaccta
     5041 ttataacaca tttatcatcg gataaaaaaa gaaaatcact cctgtagact tggctacaaa
     5101 agtgatttaa gtgattattc catttcaaaa acatcgcttt cttgcttgtt tggtagaacc
     5161 aatgagagca agattccaac aatggctggc accaaccatg ggagagatgc cttggcaaaa
     5221 ggaagaacgc taacaagatt tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt
     5281 gcaatggcaa taactgtaac cacagcaatt gtcaactgca tacctggttt tgaaagggca
     5341 acaaatttgt tgacaatgac aatcataacg atagcaatcg tgattgggta caagataacc
     5401 agtactggaa ttgagtactt gataatcgca tcaagaccca aattggcaat agcaaatcca
     5461 atcaaggtaa aggctgtcgc ataaaccttg tagctgattt gtgggaagcg ctcattaaag
     5521 aactcagctg ttgacacaat caaaccaaca gtcgttgtga agcaggttac ggtaaccata
     5581 gctgcaagga agagttgagc tgttgagcca aagatttctt gagtggcttg tgacaagatg
     5641 taaacacctg gtgttccacc cttcatcgct tcagctggta ctgggaaatg atttccaaga
     5701 aaacctaaac cgatgtaaag agcgctgaag gcaagggcaa caacgatacc aacaacccaa
     5761 atagttgaaa tgtattcttt cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg
     5821 attacgctaa aggccactga agcaagggcg tccaaggtat tgtaaccttc taggaaacct
     5881 gtaccaaagg cagaagcttg ataagcagct gaagcagctt gaggacttgt tccaccatat
     5941 ttgatagctc ccagaacgac caagataaca atcaaaattg caaagactgg cgttaaaaca
     6001 cgtccaatgc ggtctaagat ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa
     6061 tacagaaccg taaatacaat caagccaagt cctttatttg catccgacaa aagggggcta
     6121 atccctactt cgtaagctgt tgtagcagta cgtggggtag caaagaatgg accgattgac
     6181 aagtaaagaa ctgagaggta aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg
     6241 tagatatatc ctttaggatt tagcgttcca ataataaggg tcaagacggc gataccaacg
     6301 cctgaaaaga caaaacctgc gatggcagga agaaaatgtt ctccagatag agcacctaga
     6361 gaaggcggaa aaatcaagtt ccccgcacca aaaaatattc caaacaggag caaacctgtt
     6421 agggtacctt ttttagccat aaaaatctcc ttcatattta taaaatactg acctagtata
     6481 ccacgattag gagtctgaaa aaagcatcac gaggcaaata ttaaatgttt tcaattttct
     6541 taaaaataag aattatctaa aaataaaact ctcctaccca gtccacacca agcaggagaa
     6601 atgcaaaatt ttaaagttct tcaaaggcta acatgccacc ctggacattg ataacattat
     6661 aaccttgttc taacaggaat tggcaagcac gcgccgatct cattccagat ttgcaaataa
     6721 tataatgcaa gcgatctttg tccaattaat cataactatc agccaattga ctaagcggta
     6781 ggttgtgggc acattctaaa tgaagagctg caaactcatc cacttctctc acatccacta
     6841 gagaaagctg gtcgttttgg taaagctggt aaaatgcgtc aaaggctatt tctttcattc
     6901 tttttcttct aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc
     6961 gtatgttacc gacttcgtca gttttatctg caacctcaaa gctgtacttt gagcagccta
     7021 cgactagctt cctagtttgc tctttgattt tcattgacta taaaatggtt ttaattcttt
     7081 ttttcaaatc tggcactact tctgcctcaa accaaggatt tttggccatc cagatttgat
     7141 ttcgtggtga tgggtgaact agcggaaaat aggctggcag atagtcttta tagtgtttca
     7201 ccctctccgt taccttccca ctgattttct cctgtaaata gtaggcttgg gcatattgcc
     7261 caatcaagag ggttaactga atatcaggca attcctgtaa gagctgcgga tgccattttt
     7321 ctgcaaaacc tgtacgaggc ggaagatcac ccgacttgcc atgtcctgga aagtagaaat
     7381 ccataggcaa aacagcaaaa taacctgaat tgtaaaaggt atcttcatcc acacctagcc
     7441 agtcccgcaa gcggtcacca cttttatctt tccagtaaag gcctgcttct tgagttttaa
     7501 gtcccggagc ctgaccgatg atattgatgc gagcagtttt tggcgctgca aagagaggct
     7561 caatgccacg ctctgtatag ctggcattct gtgaatccgc catgatagcc tgtttgattc
     7621 tttcgatttg agacatctac tttccctcca aaaagaagtc caagcataag atctcagact
     7681 tctatcgttt tatttgatca attcgtaaat agcttcggca tagattgctg ctgctcggaa
     7741 gagatcgtcc aaggcgataa attcattggc ttggtgcatg gtatcaattg agtctgggaa
     7801 catagcacca taggcaactc cgcgctctaa caagcgacca aaggttccac caccgatgac
     7861 ttgttcatga cctttaaagc cagtttgttt ttcatagata ttcaacaagg tttgcacaag
     7921 tggatcttcc attggcacat agtgaggcgt gtgaccgtgt tcagacaggc taacagaaac
     7981 aactggcaag ttttcaagga ttgacttgat ttgttctgga cttgttcctt ttggatagcg
     8041 gatgttgagg gcaatggtat tatcagcact tgtttcatcg aagcggaaga cgccggcatt
     8101 catagaaaga gcacccatct tttcatccac atgagcaatc ttaagatttt caccctcatg
     8161 atcgttcaag agaattttac ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc
     8221 aaactgactg aggaagaggg caaggtaagt tgcgccattg acacctgaag caggcatagc
     8281 accgtgggct gatttaccaa tgatcgtcac cttgtatttg ccagcttctt cttggagttc
     8341 tcctctaagt ttgtgttctg caacaaaggc atctagttta gcttgcaagt cagccaagtc
     8401 acctgaaacg actgctgttg ctgattctgg taccatattt tcacgtaaac cacctgtaaa
     8461 gctgtgaaga cgggcaacac ctgtattttc tcctgcaaag tggaggtatt ccgtgatatt
     8521 tcctttttca ccattgatga ttggaaattc agcatctggt gagaaaccga aatctggttt
     8581 ggcaagtcct acgtgctcaa agtagtagtc catgtctgcc cagcctgatt cttcgtctgt
     8641 tccaacgatg aagcgaactt tcttagaagt tggaagaccc aattctttga tgattttcaa
     8701 accatagtaa caagctgttg taggaccctt atcgtccgaa gccccgcgcg cataaaggcg
     8761 accatctttg atagttggtg tgtaagggtc tgtgtcccaa ccgctaccag caggcaccac
     8821 atccatatgg gcaaagattc cgagaacttc ttctccatca ccaaactcaa aatgtcctgc
     8881 atagttatca acattcttag ttgggtagcc atcgcggtct gcgatttcaa ggaatttctc
     8941 caaggctttt actggaccag gcccaaatgg atgctgggca tcagccttgc tgtcatcacg
     9001 ttctgaattg atttccaaaa ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc
     9061 tacttctgct gtaaaatcaa ttgctgtcat tttttcttct ttctatcttt tctcgatgat
     9121 ttcatctact ggcaagcggt agcttggttc caatttttcg tctgtataac ccactgtgat
     9181 caagagttct gggcggaaac ggtcttcgat ttccaaaact tcattaactt ttgatttgtc
     9241 aaaaccaaga ataatgttag aaccaattcc ttggtctgtc aatgcaagaa ccaagttcat
     9301 ggcaaccaaa cctgcattga gagctaggta gtcgctgact tgttgttcat tgtagcgtgc
     9361 aaattcagct ggcaaatttt tcatgaagta ttgaagttgt tcttctgaga aattgttagc
     9421 accaccaact cgggcaatct tacgagcgcg tttggcaagg tctgtatctg taaatagggc
     9481 aatggttaca ggtgctgatg atacctgctc aaagtttgaa ccataagcca actttgccag
     9541 ttcagcattt ttctcacgaa caactacaaa tttccaaggc tggctgttgt gggcgcttgg
     9601 cgccaaggtt gcaatttcga tagccgtacg cacatctttt ggatcaacag gcttatcagt
     9661 gaaatgcttg gtcgcatgac gttttttatt taattcaaga aatttcataa tcgatttcct
     9721 tttctaattc tactgcttcc attctaccat aatttgaaag agcttgcagg gatttttcat
     9781 gattaagttt ttctatcaca gacataaaag atatatattg gtttatcagg aaagtttctg
     9841 ataaactagc aagtacttta catttgaatg gagacagtat gaaaaaattt agcctattac
     9901 tagctatcct accatttttg gttgcctgtg ggaatcaagc tacacccaaa gagactagcg
     9961 ctcaaaagac aatcgtcctt gctacagctg gcgacgtgcc accatttgac tacgaagata
    10021 aaggcaatct gacaggcttc gatatcgaag ttctaaaggc agtagatgaa aaactcagcg
    10081 actacgagat tcaatttcaa agaaccgcct gggaaagtat cttcccagga cttgattctg
    10141 gtcactatca ggctgcggcc aataatttga gttacacaaa agagcgtgct gaaaaatacc
    10201 tttactcgct tccgatttcc aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt
    10261 tgacttctct tgaccagatc gctggtaaaa caacacaaga ggataccgga acttctaacg
    10321 ctcaattcat caataactgg aatcagaaac acactgataa tcccgctaca attaattttt
    10381 ctggtgagga tattggtaaa cgaatcctag accttgctaa cggagagttt gatttcctag
    10441 tttttgacaa ggtatccgtt caaaagatta tcaaggaccg tggtttagac ctctcagtcg
    10501 ttgatttacc ttctgcagat agccccagca attatatcat tttctcaagc gaccaaaaag
    10561 agtttaaaga gcaatttgat aaagcgctca aagaactcta tcaagacgga acccttgaaa
    10621 aactcagcaa tacctatcta ggtggttctt acctcccaga tcaatctcag ttacaataac
    10681 actcttcgaa aatctcttca aaccacgtca gctttatctg caacctcaaa gctgtgcttt
    10741 gagcaaccta cggctagctt cctagtttgc tctttgattt tcatattgag tataagatat
    10801 attaaaagcg atgggatcag ccaatcgctt ttttagtttg cattggttat tttaggaaac
    10861 tcttacaaaa aatcaaaaaa attcttcaca tcctctacat acctatgctt ttctattaag
    10921 cttgctaata gttccagatt gtgcctctga tagttatctt cacgacgtag ttcttcatac
    10981 atttcgataa agggaaaacc cttggatttg gcaaattcta actcagcctc gtaatcataa
    11041 gcgactttac gaaataggat atttaccaat tccccatctt caacctctat cacggcatac
    11101 tgggcacggt gattttttaa cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga
    11161 ttgatgattt gttgcccttg actaccataa cgaagcaact acttgtgaac atgaccataa
    11221 actgccacgt ccgtttccgc atctagcagt tggtcaaatt tctctgtatc attctcaact
    11281 agcaagtcac caccatagtt tttgtcaggt aaattatgag agatagaaaa gcgcaatccg
    11341 tcaatttctt tcttttccag caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc
    11401 attcgctcca tcaaatactg tgtcatacgc aagagctgaa cttcctgtgg gtcttctaag
    11461 ccatattgcc catctaaagc ctcaaggaca caatcatccc aattgcctcg aacacttgcc
    11521 gtgataggaa gttcctttaa cagagcgacc aagtcatttg cacctggacc agggaggaaa
    11581 atgtctccca tgagccaata ttcactggct ccttgagttt tagcatctgc aatcactgct
    11641 tctagcgccg tcgcattgcc atgaacatct gataaaattg cgattttatg gtttattgtg
    11701 gtttccttcc gtttggtaat ctactctttc ttccgccact tgaagcaaga tttctgtttc
    11761 ctgcgggttc aacttggttt gcacagcctc tgctactgct cttggtactc caacttcgac
    11821 aatctcatcc acactggctt ccttgatttt ggtcagagac ttgaagtgcc tcatgagatt
    11881 ttgcttgcgt ttaggtccca gaccatcaat cccatccaat tgagatgaga aagaattttt
    11941 ggagcgcagt tggcggtgga aggtaatggc aaagcggtgg acctcatctt gaatgcgttg
    12001 gaggaggaaa aattcctgag aattgcgaga caagtccacc acttccagcg gatctccaaa
    12061 gagcaattca tgggtttggt gcttatcatt cttttgcaga cctgcaattg gaatatccaa
    12121 gcccagttct tcttggatga cttgcttagc aatattgact tgaccttgcc ccccatcaat
    12181 cacaatcaaa tctggaggag tcaaagcctc acgctgtact cgaccatagc gtctgcgaat
    12241 gacctctcgc atactggcat agtcgtctgg cccgactacg gtcttgattt tatacttacg
    12301 gtaatctttt ttacttggcc tgccgttaac aaagaccacc atggctgaaa caggactggt
    12361 ccccatgatg ttggagttat cgaaggactc gatgcgaact ggagtcggaa tttggagcaa
    12421 acgtcctaga ttttcaatag ctccttgggt cttttcgact gatttttcta gcaggttaaa
    12481 tttctgctcc agactaacac gtgcattttt tatggctaga ttgaccagct gttttttctc
    12541 tccacgttgg ggtttgagaa tcttggtatc caccaaagcc ttgacagctt cttcgtcaat
    12601 atcctgcgga atcagtacct cattgggaac taggtgagat ttttcttgat agaattgtcc
    12661 cacataggtc aagaaatcct catctggatc attgaagtag gggaagagat tgacatcgcg
    12721 ctcgatgagc ttgccctgac gaacaaagaa aacctgcaca cacatccagc ccttatccac
    12781 atagtagcca aagacatcgc gattttggag atccttagcc atgacccgtt gcttggttcg
    12841 aagcgttcca atagcctgaa tcaggtcacg gtattccgcc gcacgttcaa actccatagt
    12901 ctgggctgcc gctgccattt tgccctttag ctcatcaatg attttgttat cctgcccttt
    12961 cagaaaatca gaaacctcct gggccataga cttgaaataa gcctcatcct tcttacagat
    13021 ggtgtgagcc atacactggc cgatatggta ataaaaacag accttagagg gcgggttggt
    13081 acacttacga aaagggaata tccgatccag caaccgcttg atttcattgg ctgcccccac
    13141 atcgggatag ggtccaaaat aaagacctcc gtcctttttg acctgacgag tgataatcaa
    13201 gcgtggatag cgctcattgg tgattttgat gaaaggatag gacttgtcat ccttgagcat
    13261 gatattgtac ttgggcttgt tttccttgat caggttgatt tctaggagaa gtgcctcaat
    13321 attagactcc gtaacaataa attcaaaatc cacaatttca gacaccagag cctctgtctt
    13381 ggtatcatga cttccacgaa aataggaccg tactcgatta cgcagatttt tagcctttcc
    13441 tacatagata atggagccat ttttatcctt atgaatgtag caaccagggc tggtcggcaa
    13501 gagctctagt tttgatttaa tcaagttgtt catagttcca ttatagcaaa aaaagtaggg
    13561 aaagatagta ccctactcac tagtctcata tatttttcgg aggtttgcaa catcctcttc
    13621 ctggatacca taaaaggaac ctgctggttg catgacagac ttctcatctg tatggtccaa
    13681 gccaatcgca tgacctaact catgttctgc cgtatggaca aggcgttcat aggagtagcc
    13741 atagtgtgga ttggacaaat aataatgatt caaccgcacc gttacggaca agaattgccc
    13801 tgctaagaga ttagtttgac tttccgcctc tcctgccaca ggagtgcctc cgtcgttcat
    13861 ctccgtagcc gtaatatccg ccttactaga ctcagtcacg agttcaaagt taaaagcacc
    13921 agtttgattc cagttctgga ttgcttctaa ataagcctct tgaaagcgtg aatccatctg
    13981 cggatccagg taaatacgag cagaggcctg tgcccacctt ccttcagaat gctggtgact
    14041 atctgtctgg cttaacttag gcagttgccc tgttttctcc cattggtcaa tactttgttg
    14101 accaattttt actgaccgtt ctgcttgctt tagcgctcct tgaaaatccc cgttcagata
    14161 ccagagaagt ccgaaagcaa gcacacataa gagcacaact atccaaacca gacgccaaaa
    14221 caaacgccac acaaaagaaa agaaagcccc tatcaaacga aaaagccagc gcatgtctct
    14281 ccacctttct agcaaataag aattatttta ctaaaagaag ctaaaagaaa tctaaatact
    14341 gactttttca tcttaacgtc ctactatttt tttgagtaac tggatagctt tgtattttaa
    14401 aggcgatgga tggtaacgga aagtacccgc tttgcgtaca atatagccat taaaattctg
    14461 tttaaaacgc aaaacaccat cacttccatc aaaaatccct tgaatgccta ggaaattgta
    14521 tttaggtatt ccacgtttta tgctttccaa cataacatat ttttgaagca gtgcaggggc
    14581 atagaactta ttaaactcag tgtaggaacc actaaagaga taagtcgttt cctgaggcat
    14641 ataaacaaat aaactcccag ctaaaacaat atcttcttct ccatattttt caatcaagtc
    14701 tcgcgcttct gcttttcgaa cttcaaacgt ttcaaattga ctagaatatt ctctcagttg
    14761 attttgtttt ttctcagaat gaggattttt actcaaatca agtcgcaact tgtccaagtt
    14821 ttcttctagt ttactttgtt caccttgcaa tttgctcata tactccgaaa aattcaagct
    14881 tgctatgaga aactccgctt gttctccaaa agtatcataa aaatactcat aatattctaa
    14941 acttttatca ctatattctc tacgttcaga ggtttctttt gttatattct taaaaatcga
    15001 tagttcttca cgttttaact ttttcaaccg aatgccaaag gtttcagcct ttttcaccaa
    15061 gggtttaccc tttttgctaa aacttttaag caaactcttt tcagttaatt cagttaaatc
    15121 tttatagtat aaccaatctg gttctccacc tgggtaacct gttgttaagc catcaaattg
    15181 ataacctaaa tcagtcaaac cttgaataat actttttttc tcagcatcta ttggattacc
    15241 ttggctatca aaagtttgat aagtttcata aggttttaca agcaactcta atacaccatt
    15301 ttgcttggca tattctttta actctgcata aaaaactgga agagcatctt gttgggtata
    15361 aatcggcccc gaattgagtt ccatatgcag accacccagc atgggcaggc tataaaccag
    15421 agctgcaact tgaatttctc cttcttgttt caaagcaaga taaacaattc gagcccctct
    15481 tttttctagc aaatccccca tctggacaga ttgcataaag gaacgagaag aaacctgatc
    15541 agaataagtc tgaaactctt ctttcgtgag tgttgttagt gccatatact tactttctat
    15601 gtttttttct taatgtttta cggaaatcaa gagcaagtct taacagagga tagagaggat
    15661 gagtgggcat tgtaaattca cccaagtatt cttcaatcgt tggattaaat ttttccttaa
    15721 aatgataaag tccaccattg agagagtttt caacaccacc taaattttgc cagaccatac
    15781 ctcgctcaaa ggcatagcga gccgtttcat accatgttaa aattggtgca ttgtaacgtt
    15841 taaaatcatc atccatacca gcatatatat tgacagaggt agtaccaaat tccaaactca
    15901 aagtagccgc taaaggaact ctcgcttgac ctacatctat atattcctgc aagaaggtca
    15961 attcctctaa caaacgttct ttttccttct tctgcgcttc tacttttgaa gttcgagtcg
    16021 actcagtaaa cgtctcttcc aaggctctat ttttcgctaa ctgttcttct aactcttgcg
    16081 aacgtttaga aacatccaag gtggccaagg tgatataggc cttgtcctta aaattatcta
    16141 acaatttttt ataataggct tcattcctca aatgaatctc ttttcgcttc tcagtttttt
    16201 tcatcaactc cgaaaatgaa tctaatagtt ccagtccacc atattgaatc tcaagccctt
    16261 tgtttcgtgc tgttcgaata gcctgttttg ttgacttgga aagtttatct tcttcaaaat
    16321 tttccttgta tattttcgcc tgaatacgag gttgaatggt gtctcccatt tcctccgttt
    16381 ttcctgacca ccttactccc atttgttgca aactatcaat aatagccaga ttttcaggaa
    16441 attctgtctt ttcctgattg attaaacttt gagataggca aatacttggg tcaaaagtca
    16501 caaaaaccgc tctcttactg cgagcatagg acttaataga ctgaatgaca aaattcaaga
    16561 gttctttatc cccataatcc aatataggtc ctcttgggat gtaaaacatt ttatagccta
    16621 gcggaagagt tctaatcaaa atactagctg tcgccagtaa tttttcttcc ctgtaaacac
    16681 caaacttctc atgttgccaa ttagacttaa cttcctccca agcactactt tgtaatacat
    16741 tggctaattc atgttctttg acaaactgat catattctaa tgtgggaatg ccaatttgat
    16801 aacggtacat ttcctactct ctttcctcca gtattttatt actattctac tactttcgtt
    16861 tgaaaagtct agtgaaaaca tattttattt tagttctact ccccctatgc tgaagttcaa
    16921 actaagtcag tctctcttct aatttgaaat caattggtag ggttgttaaa aaaacttcca
    16981 attgtttttc ccagtagtac cactcgtgag ttccagcgct atggctatag gtcacatcaa
    17041 aacctagttt tttgagattt ttcactgcga gattattggc ttcgtacaag aaatcctgtt
    17101 cgccacacca cgcccaaagt ttggtctttt tatccgattt tttagccaga ctttcaagag
    17161 aatagggact agttgtccag tctttaatct ctccaaaaac acctctccag taggctggac
    17221 ttcccagatt ttgactttca ggagaaaagt tttgaaagct gagggcacct gaaaagctag
    17281 ctgcatgaga aaaacgattt gtcgcaagag ccagtttgaa gcagccgtag cctcccatag
    17341 aaagaccagc gataaaggtc ttttcacgct tgctagtcat attagggaag aagcgtttca
    17401 gaacctgtgg caattcctct gctagagccg tgtagtagtc aaaaccatac tgggtatcgg
    17461 tgtaccaacc attgctggta ttgggcataa caacgatgag attagttcct cgaagcaagc
    17521 gttctacatt ggtccgctta agccaactat tatgatttcc agacatcccg tgcaaaaggt
    17581 acaagacggg aatatcttca cactctggtt cttccactcg attggcatca gggtagagga
    17641 cattcacccc ccactccata tccaatactt gtgagtaata ctcgattttc attactgcca
    17701 tgattttctc cttctatttt tctataagaa aaagccgaaa ctcgactttc tctctgttta
    17761 tttcaacgat tattttgctt ccatgactac tggtaaaata gctggacgac gcttggtttg
    17821 gtcaaagaga tacttggtca aattatctcg aaccttccct ttaagatctg cccagtcaaa
    17881 gtcatctcct tgaagatact cttctaccgt ttggttaatc aattctgaac tttcacggag
    17941 aatatcgcga ctcttcttga gataaacaaa tccgcgcgta tgaacacgag ccctagccac
    18001 aattttcttc tcacgacggt tgactgtaat agccacgatg aaaattccat cctctgacaa
    18061 gaccttacgg tcacgaagaa caacatttcc aacatcacca atggcattcc catcaatcaa
    18121 gatatctcct gctgaaaccg atccagctgg aacaaagtct ccattctcgt aagccatggt
    18181 cgtccccttt ttaggaatga agatgtgttc tggcaacatc ccaactgcca tggcagcctt
    18241 agcgtgagca tccaactcac gatactcccc ttggacaggg aagaggtact taggttgcaa
    18301 aagattgatc atcagctgca aatcacgcac atttccgtgc cctgatacat gtaaactttg
    18361 ggtaatcaat ttgacaaccc cacctgcctg ataaatcata ttttccacac gcgcaacaaa
    18421 ggcttcttta gcaatagacg gagccgtagc aatatagacc aggtccccat ccttgatttc
    18481 tacataacga tggcgaccaa tcgacatctt acgaagtcca ttgataggtt cacccatacg
    18541 acctgtctca agaataatca actcatggtc ttcaaagcga gacatatctt taggcttaat
    18601 caagagaatt tcgttggcta aagacaactt cttaagacga atcgctgtgc ggacgatatt
    18661 ttcaatatca aatcctgtca agacgatacg tcgacctgtt ttatccgcag cgtcaaaaat
    18721 ctgctgaata cgagaaagat tactggaaac agctgcaacg atgatacgac cttcccagtc
    18781 agcaatagtt tgggtaattt catccctaac ttcactttca ctagccacct gaatattgct
    18841 gtctgcattg gccgaatcac tgaggagagc caggacgccg tcacgaccaa tctctgccaa
    18901 acgagcaaaa tcagttgcat aagattcact agccgtttgg tcaaatttga agtcacctgt
    18961 ataaacgatg cttccttccg atgtcttcaa gacaattccc agactctctg gaacggagta
    19021 agtcgtaggg aagaaggaaa ccactgtccc accaaaatca atctccgtat tctcatcaat
    19081 gacatggaaa tcattaaatt tcttaacggc atcatttcct ttgacaaaga gctttgccaa
    19141 ctcaatggtc aactcagacc caaatacagg aactttagcc tctgccaaga gataaggtag
    19201 agcaccaatg gcatccgcat gcccgtgggt caagaaaacc ccagcaatac ggtcgctatt
    19261 ttcaaaaagg taatccatgt ttggaatcac cacatcgacc cctaattgtt cattttcagg
    19321 atattttaac cctacattca aaacaaaaat ggactctcca atttcagcaa tgtacatatt
    19381 ttttccattc tcacgcacac caccaagtgt tgttaaactg atattactca tttttcctcc
    19441 aaaatcttag tttatcttga ttatagggca actctaccct cttattctaa aagttctaat
    19501 actttcagcc gaatcttttc ctaccattat accatttttt tgatgatttt caaaatgaag
    19561 gtctgttttc aaaaaagagt tgatttccca actctttcct aacttctact ctttttccat
    19621 caaaaaatca taaatttctt gcaccgtacc cagcgccatc atttcttggt ctttaacggt
    19681 ttgtttgaga ttttggtaaa tttgactttc tcctatctcc cgctttggcg cctctttatt
    19741 gactgtcatc acaccatctt ttatcgtcac aaagcctagt tcttcaaata cttgaatcat
    19801 cttgaccagc aagatttgtt gaatattaag atatgcagcc aaatctttca gcttgtagcg
    19861 aatatcaaac tctgggaact ggtaaatagt cttgtacaat ttggcaaact gatctctagt
    19921 cccataacct gtcagataat aggccttgtc aatatcattt ttgaaataga cagcagagaa
    19981 atgctgttcc tgaaaaatgg tcttcagctg agtaatatcc tctggaatgt tttttacgac
    20041 aatagcttca ctagccgcaa gatttggcag ttctccagga aaatccaaga ctggaacacc
    20101 ttctggcaag actgcatttt ttccacgaat gttaaaaagt tgaacacctt ccactcgcgc
    20161 atccaccatc atcaactgga gggcagtttg gccattccat tggttgacag acaatttaac
    20221 cgctaactct agattcttgg tttgagaaaa ctctgtcgcc catctgcctt gaccaaaggc
    20281 taccacttca aaactcgccc cacccttgga aattttcagc tttagatggg cattacctgc
    20341 ccccatagta cgagcacttt cgacctgaaa attcttgata taaaaaatag gtttctgatt
    20401 atccattcca aaaggagcta aacgttcaaa acttttgacc gtttccaagc taagtgcctc
    20461 caaatccaac tcttcatcta ggtttaactt attcttgcca ccagcatctg cacctttttc
    20521 acgaacataa tcttccaaaa cctgagataa atctgagagt tgctcaactt ccagcgtcat
    20581 acccgctgca cctgcatgac ctccaaaggc gatgaagagg tctcgatggg gatccagagc
    20641 ttcaaaaata tcgaccgctt ccacactacg agcactgccc ttggcacgac cgtcttctat
    20701 attaagaaca atgactgtct gtcccaattc ttccaataaa cgaccagcca cgattcctag
    20761 aaccccagga ttccagcctt ccttggccaa gacctgaacc ttcttctcag gatccaccat
    20821 ggtcttggct tcttcataga tagactgaac gatttccttg cgctcttcgt ttttctggtg
    20881 aatcataagg gcaatctcat gcgcttcctc atcatcaaat ccagtcaaca aatcaatggc
    20941 aggattggga tcatccaagc gacccaaggc attcaaacga ggagcaatct ggaaaccaac
    21001 cgtttcttct gttacttcgt tggcagcaat cccagccatg tccagcattt cttgcagacc
    21061 aatgcgctgg gtatgaccca acatttccag accatattga actaagatac gattttcatc
    21121 cgtcagactc accatatctg caatagttcc aatagcgacc aaatcaagca attccacttg
    21181 cacttcttct aacagggcac aagccaactt gaaagcaact ccacaaccag ccaaatattt
    21241 aaaaggataa tccgcatctg gatgttcagg atggacaata gcataagcat ctggcagggt
    21301 ttcaggcatg gaatgatggt ctgtcacaat gacatctact cccatagact gagccaatgc
    21361 aatagcctca tgaccagcaa ccccattgtc caccgtcaca atcaaggaaa ttccttcttg
    21421 ctcgataaag tatttataaa cactagcatt agggccatag ccatcggtaa aacgatttgg
    21481 caggtaaact cggcactccg caccaagttg ttccaaactt tccttcacaa tagaagccga
    21541 agtcatgcca tccgcatcgt agtctccata aacgagaata ttttcccttt cttcaatagc
    21601 ctgacgaatc cgctccactg ccttgtccat atcatggagc agataagcat catgtaagtc
    21661 ctccaaggaa ggttctaaaa acttcttcag actttcttgg tcctgaatcc ctctctcaaa
    21721 caataaccga gccacctcag gacccagtcc agccttcttg gctatctttg taaaatccgc
    21781 atcttctacc tgcagggcaa actgccattc ataagtaggt gttatcaaaa agacatccac
    21841 tccttctaag aattctattg cttcattata acatgattta gacgttttct ctatccagat
    21901 tgctttttta taacatttca tagtatattg aaactagaat agtacacctc tacttctaaa
    21961 atattgttag aaatcgattt gactgtcccg atcgattttt cctgttctta tttcactata
    22021 gtgaattttt tcagatatgg tttgacaaga acattctttt attgcagaat tgtgttataa
    22081 aatctaacat aaaggagttc tctcatggct ttagtagaat ttaaaaacgt cgaaaaatat
    22141 tacggagact accacgcact ccgcaacatc aatctccgtt ttgaaaaagg acaagttgtt
    22201 gtcctgcttg gaccttctgg ctctgggaag tccactctta tccgtacgat caatggttta
    22261 gaggctgttg acaaaggaag tctcctagtc aatgggcacc aagttgctgg tgccagccag
    22321 aaagatttgg tacctcttcg caaggaagtc ggcatggttt ttcaacattt taacctttat
    22381 ccacacaaaa cagtgttaga aaacgtgaca cttgcaccca ttaaagttct aggaattgat
    22441 aaaaaagaag ctgaaaaaac cgccaaaaaa tatctggaat ttgtaaatat gtgggacaag
    22501 aaagattcct atcccgccat gctatctggt ggacaaaaac agcggatcgc catcgctcgt
    22561 ggtcttgcta tgcatccgga actcctcctc tttgatgaac caacatctgc tcttgatcct
    22621 gagactatcg gagatgttct agcagttatg cagaaactgg cgcgtgatgg gatgaacatg
    22681 atcatcgtta cccacgaaat gggctttgct cgagaggttg cggaccgcat tatctttatg
    22741 gccgacggag aagttttaga ggttgcggac cgcattatct ttatggccga cggagaagtt
    22801 ttagtagata cgacagatgt cgataacttt tttgacaatc caagcgaacc tcgtgcccaa
    22861 caattcctca gcaaaattat caaccacgaa agtgacaaag tcaaataagg aggcgcctat
    22921 gaaaaaaaat tctttttatc agcattattg attagccttt tcggccttgc tgctgccaaa
    22981 ccagtccagg ctgatacaag tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt
    23041 gtcaaacaag acgttcccaa ttttggttac aaagatccca agaccggtac ttattctggt
    23101 atcgaaaccg acttggccaa gatggtagct gatgaactca aggtcaagat tcgctatgtg
    23161 ccggttacag cacaaacccg cggccccctc ctagacaatg aacagggcga tatggatatc
    23221 gcgaccttta ccatcacgga cgaacgcaaa aaactctaca actttaccag tccctactac
    23281 acagacgctt ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta
    23341 aacggcaaaa ccatcggagt cgcccaaggt tctatcaccc aacgcctgat tactgaactg
    23401 ggtaaaaaga aaggtctgaa gtttaaattc gtcgaacttg gttcctaccc agaattgatt
    23461 acttcccttc acgctcatcg tatcgatgcc ttttccgttg accgctctat tctatctggc
    23521 tacactagta aacggacagc actactagat gatagtttca agccatctga ctacggtatt
    23581 gttaccaaga aatcaaatac agagttcaac gactatcttg ataacttggt tactaaatgg
    23641 agcaaggatg gtagtttgca gaaactttat gatcgttaca agctcaaacc atctagccat
    23701 actgcagatt aaggaggaca ccccatgaca gatttatcat cttggacagc ctattttcag
    23761 gattttggac aatttttcaa tggtttcctc ttcacccttg ccctagcgat tggatccttt
    23821 atcctcgcca tggtcttagg aatcttcttt ggtgccatgt caaccagtaa acgtccaatt
    23881 ttacgcattt tagctcgcat ctttgtggaa ttttaccaaa acactcccct cttggtgcag
    23941 tttgttattg ttttttatgg cctacctctt atcagtgacc atactatcat gattccgatt
    24001 tattggacag ctgttctctg cgtgggactc tatcacggcg cttatatcgc tgaggttatt
    24061 cgttcaggga ttcagtctat tcctagtggt cagatggagg ccgccttatc gcaaggtttt
    24121 acctatatca gtgccatgcg cttgattatc ttgcctcaga ccttccgcat cattctccct
    24181 ccattgacca accaaattgt taacctcatc aagaacacct ctactgtagc tatcatctct
    24241 ggagtagact tgatgtttgt gactaagtct tggtcggctc tcaacggaaa ctatatccca
    24301 gcctttttag gtgctgctct tctctacttt gccctatgct tccctgttgc ccagtttggt
    24361 cgcaagatgg agcaagccaa caaaaaagcc tattcacttt aggaggttac tatggaatct
    24421 attttagaag ttttaacccc agataaccta gtctttatct ttaaaggatt tggcttgacc
    24481 ctctatattt ctctgattgc catcatcctc tctactatca tcggtacggt gctagctgtc
    24541 atgagaaatg gcaaaaattc tgtcttgcga atcatctcca gtatttatat cgagtttgtg
    24601 cgcaacgttc ccaaccttct ctggattttt actatctttt tggtgttcaa aatgaaatcc
    24661 acaccagcag gtattacagc ctttactctc tttacatcag cagccttggc tgagattatt
    24721 cgaggcggtc tcaatgccgt agacaaggga caatacgaag caggaatgtc acaaggcttc
    24781 acctcagccc aaatcctcta ctacatcatt ctcccacaag ccatccgcaa aatgctacca
    24841 gccatcattt ctcagtttgt taccgtgatt aaggatacca gtctcctcta ctctgttatc
    24901 gccctacaag aactctttgg agccagccaa attctcatgg gccgttattt cgaaccagag
    24961 caggtcttca gtctttacat cctgattgcc ctcatctact tcagctttaa cctagcaatt
    25021 tctagcctgt ctcatatgct agccaaacgt tggcaacaag ccgcagaata atactcttcg
    25081 aaaatctctt caaaccacgt cagcttcacc ttgccgtata tatgttactg acttcgtcag
    25141 ttctatccac aacctcaaaa cggtgttttg agcagcctgc gggctagctt cctagtttgc
    25201 tctttgattt tcattgagta taaacagcca ctctccaatt caattggaga gttttttgat
    25261 gagagtagat atttatagac ctcaatttga caccatacat tttctatgat aaaatgtaac
    25321 aaattcattt acaacaaatc gaaatctaaa tgaaatggaa ttttctatga aatcagtcaa
    25381 aggactactc tttatcatag ctagttttat cttgactctt ttgacttgga tgaacacttc
    25441 tccccaattc atgattccag gactagcttt aacaagccta tctctgactt ttatcctagc
    25501 cactcgtctc ccactactag aaagctggtt tcacggtttg gagaaggtct acaccgtcca
    25561 caaattcaca gcctttctct ccatcatcct actaatcttt cataacttta gtatgggcgg
    25621 tttgtggggc tctcgcttag ctgctcagtt tggcaatctt gccatctata tctttgccag
    25681 catcatcctt gtcgcctatt taggcaaata catccaatac gaagcttggc gatggattca
    25741 ccgcttggtt tacctagcct atattttagg actctttcac atctacatga taatgggcaa
    25801 tcgtctcctt acatttaatc ttctaagttt tcttgttggt agctatgccc ttttaggctt
    25861 actagctggt ttttatatca tttttctata tcaaaagatt tccttcccct atctagggaa
    25921 aattacccat ctcaaacgct taaatcacga tactagagaa attcaaatcc atcttagcag
    25981 acctttcaac tatcaatcag gacaatttgc ctttctaaag attttccaag aaggctttga
    26041 aagtgctccg catccctttt ctatctcagg aggtcatggt caaactcttt actttactgt
    26101 taaaaattca ggcgaccata ccaataatat ctatgataat cttcaagccg gcagcaaagt
    26161 aaccctagac agagcttacg gacacatgat catagaagaa ggacgagaaa atcaggtttg
    26221 gattgctgga ggtattggga tcaccccctt catctcttac atccgtgaac atcctatttt
    26281 agataaacag gttcacttct actatagctt ccgtggagat gaaaatgcag tctacctaga
    26341 tttactccgt aactatgctc agaaaaatcc taattttgaa ctccatctaa tcgacagtac
    26401 gaaagacggc tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat
    26461 gtgtggtcct atttctatga tgaaggcact tgccaaacag attaagaaac aaaatccaaa
    26521 aacagagctt atttacgaag gattcaagtt caaataagta atcatactct cctgggattt
    26581 cccaggagag ttttttatag ccaaatgaaa taagaccgga acgatggaat tttggcattc
    26641 aaatcaattg ataagaatat tttatagtgg agtgaaatag gatacgaaca aattgattag
    26701 gaaaatcaaa tgaatttata gaaatctttt agcagttatg ttgtcctatt ctagtttcaa
    26761 aacgctatag aagcagcatt gtactagtct agattcagtt tactatacta aaacgagtag
    26821 cttgaaatca aaaaacccac cctcacaggc aggttttatc tgtattattc agctagatta
    26881 tgctttacct tctgaaccga atacgtcgat acgttcttca accgatgctt ggatagcttt
    26941 tacaccgtca gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc
    27001 gtttgcttcg tagtcacgag caaatttacg agttgcgtta gcgaatgcga tttggcattc
    27061 tgtgttaacg ttaactttgg caacaccaag tttgatagct gcttggattt gctcatcagg
    27121 aatacctgat ccaccgtgca atacgattgg gaatcctgga agagcttctg tcaatttttg
    27181 caagtggtca aggtcaagac cttcccagtt tactgggtaa gggccgtgga tgttaccgat
    27241 accagctgcc aagaagtcga taccagtttc aaccattgct ttagcgtctt cgattggagc
    27301 caattcacct ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc
    27361 tactgagata cctttagcgt gtgctttttc aacaacttct ttagccaatt taaggttttc
    27421 ttcaactgga aggtgtgaac cgtcaaacat gattgaagta taaccaactt cgatacactc
    27481 aagtgcatct tcgtagtgac cgtggtcaag gtggatagct actggtacag tgatacccat
    27541 tgattcaaca aggttagcga tcaagttgcg agcaactttg taaccaccca tgtatttagc
    27601 agcacccatt gaagtttgga tcaaaactgg agctttttta gcttctgctg cgcgcaagat
    27661 agcttgagtc cactcaaggt tgtttgtgtt aaatccacca actgcataac cgttgtcacg
    27721 ggctgcttgg acaaattttt ctgctgaaac gattgccatt ttatcaggcc tcctgtatat
    27781 ttttatgggt catcccattt acattgttca ttttatcact ttttgccaaa aaaatctagt
    27841 ttttcccgca gtttcgattg attttcttct aactccatct atgtaaaccc tttctctccc
    27901 tagtcttggg cgacttttgg aaaagctata aagaaggtta aacgattctc ctccatctcg
    27961 aaacgataag ctaatttttc atgttctaat agactcttaa ccacaaagag ccccatacca
    28021 gaccccttga ccttgcgact ggcattgtca gaaaaagact gggctagttt ttcttgttcc
    28081 tctgagctac agctattttc gataaaaagt tctccttctc tttctccaat tcgaactaag
    28141 ccacctggaa cagagtgctt aatggcattg ctgatgagat tagaaagaat caacttcata
    28201 actgatgggt ttagataagc ctgctgatgg gtcaaactat tgtctatctg gagctctctt
    28261 tccttggcta gcaaggcata atctttgacc agattttgcg tcatctggag gaggtcaatt
    28321 gtttccctat catctcgcaa ttcctgcaca gaagagaggg aaagtatctg cagaacatgg
    28381 tgattgagtt catccacaat ccccaaggca actcccagat actggtctct atccttataa
    28441 cgaccgatat tctctctcat attttcgatt aggattttca aactagccag cggtgttttc
    28501 aattcatgag aagctcctcg taggaattcg accttcatct tctccagctg gagaatggct
    28561 tcattctttt catgcaagtc cgcaataaca gtcaagagat gctggtagag gctattgatt
    28621 tgttccttga gattacctat ctcatcctta gaatccacgc gcaatcgcac ttgggaatcc
    28681 aggtccatca tccgacgggt cacccgcttg atttccaaaa tcggtgcaac aatagtccgg
    28741 gcgtagatgt aggccaccaa gagggaaatc agaaaggagg ccagcaaggt atagggaaga
    28801 aactggagac tgatttgctc cgcttccttt tgtaaatcca tggaagctag aaactggaga
    28861 atcatagtac caccgtcttg cgttttcacc tcgcgctcct caataaagag agaggttgtc
    28921 tggcggtctg tgtccagagg aagactgtcc ttgacttcta acttgtcctc ggtcatctca
    28981 cctttgacgg tccccttgat atcactagtc tgggaataca agtctaacac ttgctcgata
    29041 ctctgcctat ctttcccttc tagggactgg gcaatggctg ttgccttttg accaatggtt
    29101 tcctgacgat gactcagata agtcgaagga aaaagaaaat aaatagctaa atgaaggcag
    29161 ataaccagaa cactaaatat cgagaaggta tagataaata tctttgcaaa taaacctgtt
    29221 cgtttcattt tcgctccaat ttataaccaa cattgcgcac agtgaggata caatccaagt
    29281 ctagcttttt ccgcaattcc ttgatataaa catcaataac acggtcaaag ggaacctcat
    29341 ctgtcgcttt ccagacggca tcgataatct gagaccgagt caaggcccgg ccttcatttt
    29401 tcactagata gtccagaatt tccaactctt tggcattgat aggcacttct tgacctgcga
    29461 ggcttgcact gtagctttca aagtccacct tggtatcctt gtaagaaaag attcgtcctg
    29521 tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt taagagggag agagagaaag
    29581 gtttttccag atagccatct gccaaagagg caaaggcact catcttgtat tcctcatcct
    29641 gaaaagctgt caacatcaag acaggaacct gactggtttt acgaatctca gctaggactt
    29701 ctaagccgtt aagcttgggc atctggatat ccagtaaaac cagggccacc tcatagctag
    29761 aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat agtttcatag ccacaatccg
    29821 tcaaataatc actgaccccc tcacggatca tctcttcatc ttctacaatt aaaattttca
    29881 tactttaact gctctctatt ttttattttt cttagaataa atacctactc tattttctat
    29941 tatagtctct tgctggcctt ttgtctgtaa gcaactgatc actagataaa acgttgtgaa
    30001 attcctttct cataaattcc ataactttag tatattatat ttaagcacta aagtacaaag
    30061 aaagcaactg aaagcaatga ttttcaccac tgctttcaga tttattttga attgttaaat
    30121 agctattcct atccactatt cttgaataga aacacaagat gcaatcttta ttccagactc
    30181 attttttcaa atttattcac catccagcaa gagctctttt ggttgttttc taaggagatt
    30241 gcttgaagca agcgccataa cgagaaccac tagaaccaag gcaaggacaa aaatgatgat
    30301 aaagtctgat gtctgaatgg aaatgtctag gctcgacaag gtcttgctaa agccatctac
    30361 ttctgcaccg ccaccaaggt tagaggcttg agccgcctta ctagcctgtt tggcaacacc
    30421 tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg gcagtgtaat tagctaggaa
    30481 gtaagcagaa actagagcag ggatagcaat caagatagat tcggtgatga attgacccaa
    30541 gatacttgcc tgcttgaggc cgatagagag gagaattccc acttccttgc gacgggcgtt
    30601 gatccaaagg ctgagcaaga gggcaaggag gagaactgag aagctcaagc taccccagaa
    30661 gaggaggttg gccatcttgt acataccaga gatagattgc tcaagagctg ggtagttaga
    30721 ggagctcttg acgagtgtgt agctcttcca gttgatacca ctgatgccat tcaactcttt
    30781 cataacatca tccaagttct tgtctgctgt tacaaagaag gttgcgtccc cataaatggc
    30841 tgtgtcttct gtgtatccat aaagttttgc agcagtgtga atgtctgtaa tagctgtgtt
    30901 ttcgtaaagt tcttgtgagt aggttactgc tgacttatta tgaccatcaa agagtccctt
    30961 gattgtcact tcaactgttt ccttggctcc tttttcatta tctgcatcgt agatattaga
    31021 gtccagttta accttgtccc ctactttcca gccgtgtttg gctgccaagt ccttgtgcaa
    31081 gaggatttta tccttgtcgt cgttggttaa gtgctctcct tcgactagtt tataagaacc
    31141 agagacaaac ttgtcttctt tagaggagtc attgacacct gtaatcatca agctacttcc
    31201 aaaacgtttg gcacgatcag cagtgagatt cttcttggtt tctggcgttt caatcaggtc
    31261 atatccagtc aaatctccga tagcgttgat acgtttgaca taagactcaa tggccttgtt
    31321 ttcggtgatt tttttgatgt cttcaccctt gatattccca gcaccgcgag gcgttccttg
    31381 gttgacgcga cgattgattt gcatggagaa gctattggtg atatttttaa aggtctcctg
    31441 agaagccttg gcagtagctc ccttgattga caagccgacc aaactcaagc tcgccatgag
    31501 gagaataatc aggaagatga caatcgattt gaaaaacttc cttgtaacat aggcaaatgc
    31561 gttgtgtaac atagattccc tttctagatt ttgttttaat cattctatta aagtaagctc
    31621 aaattattta ctagtattgc gcgtttcagt cagtttctta tcctttaatt caagtgtaat
    31681 atctgacgct tgtgccactt ctttactgtg agttacgaca atcacacatt tacctgtttt
    31741 ctgggcaagt gatttgagta gttcgacaat atctccagca gttttaggat ccagatttcc
    31801 tgttggctca tcagctagaa taactggagc ttctgagacc aaactgcgag caatggcaac
    31861 acgttgctgt tgaccacctg ataactggag aacattccgc ttgatctggc tttcatccaa
    31921 accaagctca agaagtgtat tcttgcttgc ctttttgttg accaatcgga tattttccag
    31981 cggagaaaga taatctatca agttataatt ttgaaagacc agggaaatat ggtgcatgcg
    32041 atggtaagaa tagcccttct tacgaatatc ctctccttga aaaaggatag aaccttcaac
    32101 aggactatct agaccagcaa gtagggacaa gagtgtggat tttcctgctc ctgactcccc
    32161 aataatactg taaaattttc cgggttcaaa attataattg atctgatata ggactgcttc
    32221 agcagtattc ttataacggt aggtaacatc ttgtaattgt aataaagtca tgatttctcc
    32281 ttcttaacta atagatgata aaatttcttt cggtgatttt ctaaataaga ataggaaaca
    32341 aagggctaca gataagcaac taagcagaac tagaaaaaca taggattctg caaaagataa
    32401 gatgctagtt gataaactgc ttgctttggc tagtgtatct tgtaagcttg cctgatctcc
    32461 acttgctagt agagtttgga gtaggtaagt tgtgattccg tttcctgcaa caaatgctgg
    32521 aagcaaagct ccaagagata ccaaaactac ctctaaacag aattgtagga aaatcgagct
    32581 cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag acccgttctc tcaaccagag
    32641 agacaaaacc agaattaagg ctccagctcc tgctatcaac atcccataaa ggaagatggt
    32701 caggaaggtt tggaaagttg caactgagtc tttgatttgt tcaaaagcct tgttttcctt
    32761 ttcgacttgg tagccttgat tttccaaggc caagttttct acctgcttca tgagtccgtc
    32821 catttcctta ggattttcta catagaagcg tgctgcactg acttgagctt cactattgcc
    32881 caaaagggtt tggctacttt catagtctgt aaagacttga ttttcactga agtcagaaga
    32941 caagcctgtg aatttctctt gttttttacc agaaaagatg ccgataatct caaactctac
    33001 tgtttgtcct tttccagatt cagactgacc agcatccaag ccaatcttgt catgaagtga
    33061 aagaccgttc ttcttagcca attcttcgtg gataaggatt ttcttggaat tccctttttg
    33121 aaggtgtcgc ccttctttta gattgaaagc cgaactggta aaggttacat ccttggatga
    33181 atcctcaaga gccgttaagc taaccaagtt attgtctgca gctgataaat catcacgctc
    33241 cacgctctgc tcgccagtca ctgcttcctt gtcttttagt tttgcgaccg tctcgagttc
    33301 aggagagaca ttttccagcc ccttaatctt gcttacagat gctaggtctg acaacttgaa
    33361 tgtctgacca ttctctatct tcttaataga aaaagatgta ttgagtgatt tataaagatt
    33421 gctttctact gttttgttgg acttcatcag agtcaaacag gctgaaattc cggccaataa
    33481 gaccaataaa atcagaaata aaataaaact tctcagtcgc tttctgctga cataagccca
    33541 agatctttgg attggattca tttgtcacct ccatatttgt aagactatta taaaacccaa
    33601 atatgaaatg tttatgaaat acgaaaaaaa aatatcgagt aggggataat ctctagcccc
    33661 tctca
//
LOCUS       DAVLAQ010000023        32355 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000023 DAVLAQ010000000
VERSION     DAVLAQ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.023"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            100..534
                     /locus_tag="VXB71_001054"
     CDS             100..534
                     /locus_tag="VXB71_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0451182.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQESVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            546..1736
                     /locus_tag="VXB71_001055"
     CDS             546..1736
                     /locus_tag="VXB71_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0451183.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1747..2238
                     /locus_tag="VXB71_001056"
     CDS             1747..2238
                     /locus_tag="VXB71_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0451184.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2253..3032
                     /locus_tag="VXB71_001057"
     CDS             2253..3032
                     /locus_tag="VXB71_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0451185.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3019..3837
                     /locus_tag="VXB71_001058"
     CDS             3019..3837
                     /locus_tag="VXB71_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0451186.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3837..4130
                     /locus_tag="VXB71_001059"
     CDS             3837..4130
                     /locus_tag="VXB71_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0451187.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4152..6053
                     /locus_tag="VXB71_001060"
     CDS             4152..6053
                     /locus_tag="VXB71_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0451188.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6113..7114
                     /locus_tag="VXB71_001061"
     CDS             6113..7114
                     /locus_tag="VXB71_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0451189.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7224..7559)
                     /locus_tag="VXB71_001062"
     CDS             complement(7224..7559)
                     /locus_tag="VXB71_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451190.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7570..7812)
                     /locus_tag="VXB71_001063"
     CDS             complement(7570..7812)
                     /locus_tag="VXB71_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451191.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7828..8022)
                     /locus_tag="VXB71_001064"
     CDS             complement(7828..8022)
                     /locus_tag="VXB71_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451192.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8188..9138
                     /gene="rsmH"
                     /locus_tag="VXB71_001065"
     CDS             8188..9138
                     /gene="rsmH"
                     /locus_tag="VXB71_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0451193.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPEGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9150..9467
                     /gene="ftsL"
                     /locus_tag="VXB71_001066"
     CDS             9150..9467
                     /gene="ftsL"
                     /locus_tag="VXB71_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0451194.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9471..11723
                     /gene="pbpX"
                     /locus_tag="VXB71_001067"
     CDS             9471..11723
                     /gene="pbpX"
                     /locus_tag="VXB71_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0451195.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11725..12705
                     /locus_tag="VXB71_001068"
     CDS             11725..12705
                     /locus_tag="VXB71_001068"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0451196.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13269..15374
                     /locus_tag="VXB71_001069"
     CDS             13269..15374
                     /locus_tag="VXB71_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0451197.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(15670..16152)
                     /locus_tag="VXB71_001070"
     CDS             complement(15670..16152)
                     /locus_tag="VXB71_001070"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0451198.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16247..17731)
                     /locus_tag="VXB71_001071"
     CDS             complement(16247..17731)
                     /locus_tag="VXB71_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0451199.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            17884..19494
                     /locus_tag="VXB71_001072"
     CDS             17884..19494
                     /locus_tag="VXB71_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0451200.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVEMTD"
     gene            complement(19625..21055)
                     /locus_tag="VXB71_001073"
                     /pseudo
     CDS             complement(19625..21055)
                     /locus_tag="VXB71_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398391.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            21212..22657
                     /gene="cps4A"
                     /locus_tag="VXB71_001074"
     CDS             21212..22657
                     /gene="cps4A"
                     /locus_tag="VXB71_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0451201.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHRKFLFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTDRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            22659..23390
                     /locus_tag="VXB71_001075"
     CDS             22659..23390
                     /locus_tag="VXB71_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0451202.1"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            23399..24091
                     /gene="cpsC"
                     /locus_tag="VXB71_001076"
     CDS             23399..24091
                     /gene="cpsC"
                     /locus_tag="VXB71_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0451203.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            24101..24784
                     /gene="cpsD"
                     /locus_tag="VXB71_001077"
     CDS             24101..24784
                     /gene="cpsD"
                     /locus_tag="VXB71_001077"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEV0451204.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            24800..26167
                     /locus_tag="VXB71_001078"
     CDS             24800..26167
                     /locus_tag="VXB71_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0451205.1"
                     /translation="MDEKGLKIFLAVIQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            26173..26916
                     /locus_tag="VXB71_001079"
     CDS             26173..26916
                     /locus_tag="VXB71_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV0451206.1"
                     /translation="MNERMQILGVTIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCHEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEILQDMLKVFKQRYPNLNVVGYRNGYFSPEDEKKIQEDIKGGKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQKLNLEWLFRVVN
                     EPKRLFKRYFIGNVTFIKRVLDEKRKSKK"
     gene            26891..27976
                     /locus_tag="VXB71_001080"
     CDS             26891..27976
                     /locus_tag="VXB71_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0451207.1"
                     /translation="MKSENQKNNILHISRTMDIGGAERIVYQLSSDLKDEFDSVHVAS
                     TGGLWESKLLSKGVQHHKILDVDSKNPLTMVKILSSFYRIIKNNDITIVHTHHRMAAF
                     YIRLLKIINPKLIHVYTAHNVFKNKLPLYKFSLKKAYCVAVSKAVNDNLKHDVGISDS
                     TVIYNGVVFEKTDKLVGEIVNYNGIKLGCIARLSEQKGLTYLIDAMSLVKHRNITLFI
                     VGDGELRDELENKVKQLNLQKSVIFLGYRKDIVECINSFDYLVSSSLYEGFGLNAIEA
                     FMKGKTMVSSDIPGINEVVNNKNGILVPVKDDVALARAIEKLATDKKLREKLAYQAKK
                     DYETKFNYSLFLDNYRRLYRKLMGESK"
     gene            27973..29061
                     /gene="wecB"
                     /locus_tag="VXB71_001081"
     CDS             27973..29061
                     /gene="wecB"
                     /locus_tag="VXB71_001081"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000758382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV0451208.1"
                     /translation="MKKVMLVFGTRPEAIKMCPLVNELKQNDSIKTLVCVTGQHKEML
                     EQVLEVFKVVPDYDLGIMKANQTLFTITTSILDKIQAVLEKEKPDLVLVHGDTTTTFA
                     TALAAFYMGIKVGHVEAGLRTYNLQSPFPEEFNRQTTSIIADYHFAPTEVAKENLLRE
                     DRKNIFVTGNTVIDALKTTVQDNYHHPILEWAKGSKLIMLTAHRRENLGKPMENMFNA
                     VNRILNEFEDVKVVYPIHKNPKVRELASKVFGDNERMKIIEPLEVIDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVVAGTLKLVGTEEENIYSNFKLLLEDET
                     EYNKMSKASNPYGDGMTCKRIVDIILEV"
     gene            29103..30242
                     /locus_tag="VXB71_001082"
     CDS             29103..30242
                     /locus_tag="VXB71_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0451209.1"
                     /translation="MIKRKIYIICVLLSYFLPSFFTVGSMATLFALLSTLVKLFVTFD
                     YIPKVLLQHKVTLIDILVVLFLFFQAFAAFQSQTLYLNYVGGQFFLLGLYSFLKHFLL
                     LDCKTTIKSLFLTFILFLCVQVITQLLFPVGFDSLHPTGDNRLYFLGRKNIATPYIIV
                     GLGGFYLLNKKMNEFISLKEIIFLGLFGILSFLTQSSTAIICYGLFIFIRLLGLKENI
                     GKLYSLVSMAVYVCFSLSIIFSQSTILSTFTAIFSKNATFSGRINIWQLAIRIFEENF
                     WFGRGLNVNFNAWTNGIIVNSAHNTLLDILARTGIFPGVLFIVLLMNLFLGKYRIESK
                     TLLAMLASFMIYITMETSSMSILLLIIVLCVYWPRGEEKLHEQVT"
     gene            30226..31095
                     /locus_tag="VXB71_001083"
     CDS             30226..31095
                     /locus_tag="VXB71_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEV0451210.1"
                     /translation="MSKLLNTIYYRLFRLYKKIYLQVFSKKTVDILGEKANLENELIV
                     SFTTIPSRLNYLPSMIKSIFNQTIIPNRFIMYVYKDEFEGINLESILELEIKNGLEIV
                     YVDENLRSHKKYFYAMKDNPNSIVVLVDDDIIYPRNTIKKLIASYRIYPQCVSAMRCH
                     RIKLFSDGSLYPYNQWEYEISGATIPSYFNFFTSGGGTLFPPCTRNEDLFNKKNIREL
                     SFLADDVWLNFLVVKNGIKTVKATRYKGTPLTIDDNPEESLVYLNTVYDNNNDKCIRN
                     MVEYYQINFTEDK"
     gene            31095..>32355
                     /locus_tag="VXB71_001084"
     CDS             31095..>32355
                     /locus_tag="VXB71_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEV0451211.1"
                     /translation="MNVEKNLKRGIFYTAIGKYSNVVIQLLVTAILSRILSPVEYGIV
                     AVVNVFLLFFQMLADSGIGPAIVQNKELNKSDLISIFSLTIYSGIVLSCIFALLGYPM
                     GVLYGETIYVSLFPLLGLCVLFYTITIVPQAILMKTMNFKIVNFLTIFSNIASGLVGV
                     ILAVSHFGVYSLIFSNIVKAMVLFIALYSKAKINFYWKVSKSSIGKIFEFSKFQFLFN
                     FWNYFARNLDNLLIGRLISPSDLGYYDKAYQLSLYPNQILSQVVTPALHPIMSNFQDN
                     ISKIGEVYLQISRIFVIVGIPISAYLYFNAQYVVTFMFGDNWSQSVPVFQILAATIWL
                     QMANSPTGAFYQATNQTKLLFRIGLLTSFINILAIVIGVMLQSIQCVAYMLLISFSLS
                     LVINTLYLTKKVLNISAQKYIKPILINL"
BASE COUNT         9964 a         5356 c         6998 g        10037 t
ORIGIN      
        1 ctaatatttt tttaaaaaaa ctattgacaa gataaaaata aaggattaca atggggaata
       61 taaagtaaac cggtaaactt aaacaagaaa ggagaaaaga tgaaaattgt acttgtaggg
      121 catggacatt ttgctacagg gatttatagt tctttacaat tgattgcagg caatcaagaa
      181 agtgtggagg cgattgactt tgtggaagga atgtcagcag atgaactcaa gcaaaaaatc
      241 ttacttgcaa tttcaaatga agaagaagtt ttaatcctaa gtgatctctt gggaggatcg
      301 ccattcaagg tttcttctac cataatggga gaaaatccag ccaaaacaat gaatgttctc
      361 tcgggtttga acttagccat gttaatggaa gcagtctttg ctagaatggc tcatagcttt
      421 gatgaggttg ttaataaatc agtagtggcg gcccagggcg gagtcgtaaa tggtaaagaa
      481 ttgttttcaa cggatgcaga ggaagaggaa gaagatttcg aatcgggtat ttaaagggta
      541 aaagaatgat aaaaaaggtt acgattgaaa aaataaaatc gcctgagcgc ttcttagaag
      601 taccacttct gacgaaagaa gaagtcggcc aggcaatcga taaggttatt cggcagttag
      661 aactcaacct tgactatttc aaggaagatt tccctacgcc agctaccttt gataatgtct
      721 atccaatcat ggataacacg gaatggacca atggtttctg gacaggagaa ctgtggttgg
      781 cttatgaata cagtcaacag gatgcattta aaaacatcgc tcataaaaat gttctttctt
      841 tcctggatcg tgtcaataag agagtagaat tggatcacca tgatctcggc ttcttgtaca
      901 caccgtcttg tatggctgaa tataagataa atggagatgg agaggctaga gaagcaacct
      961 tgaaagctgc agataagttg attgaacgct atcaagaaaa aggtggtttt attcaagctt
     1021 ggggagactt gggcaagaaa gagcattacc gtttgattat cgactgcttg ctcaatatcc
     1081 aactcttatt ctttgcttat caagaaacag gcgatcaaaa atactacgat attgcagaaa
     1141 gtcatttcta tgcttcagct aataatgtaa tccgtgatga cgcttcgtcc ttccacacct
     1201 tctattttga tcctgagaca ggtcaaccct ttaaaggtgt aacgagacaa gggtatagtg
     1261 atgattcatg ctgggcacgt ggtcaatcat ggggagtcta tggtattcct ttgacttatc
     1321 gtcacttaaa agacgagtcc tgctttgact tgtttaaggg tgtgaccaat tatttcttga
     1381 atcgtctgcc aaaagatcat gtgtcctatt gggatttgat ttttaatgat ggtagtgatc
     1441 aatcacgaga ttcttcagca acagctatcg ccgtctgtgg gattcatgaa atgctaaaac
     1501 atctcccaga ggtggatgct gacaaagata tttataaaca tgctatgcat gccatgcttc
     1561 gttccttgat cgaacattat gcaaatgatc aatttacccc tggtgggaca agtctcctcc
     1621 acggtgtgta ctcatggcat tcaggtaaag gagtggatga aggcaatatc tggggtgact
     1681 actattacct agaagccctt atccgtttct acaaagactg gaacctatat tggtaggagg
     1741 agaaatatga caatgccaaa tattattatg acccgtatcg atgaacggtt gattcatgga
     1801 caaggacaac tttgggtaaa atacctaggt tgtaatacgg tcattgttgc caatgacgaa
     1861 gtaagcacgg acaagatgca acaaactctg atgaaaacag ttgtgccaga ctcagttgcc
     1921 atgcgtttct tccctttgca aaaggtgatt gatatcattc acaaggctaa tcctgctcaa
     1981 acgatcttta tcgttgtaaa ggatgtgaag gacgctttaa ccttggtaga aggtggtgtc
     2041 cctatcaaag aaatcaatat tgggaacatt cacaatgcta ctggtaaaga gcaagtgaca
     2101 cgctccatct tcctgggtga agaggacaag gcagccctca aggaattaag ccaaactcat
     2161 caagtaacat ttaatacgaa aacaactcca acaggaaatg atggagctgt tcaagtcaac
     2221 attatggact atatttaaaa gaggagatcg ttatgtcgat taatgtattt caagcgattt
     2281 taattggatt atggacagct ttctgtttta gtggaatgct attaggaatt tacaccaata
     2341 gatgtattgt tctgtcattt ggtgtcggaa ttattctagg tgatctgcct actgctcttg
     2401 caatgggagc tattggtgaa ttggcttata tgggattcgg tgttggtgct ggaggtactg
     2461 ttccaccaaa cccaatcgga cctggtatct ttggtacctt gatggctatc actagtgctg
     2521 gtaaagtcag tccagaagcg gctcttgccc tctctactcc gattgctgtg gcgattcaat
     2581 tcttacaaac tttcgcctac actgtacgtg ctggtgcgcc tgaaacggcg atgaagcact
     2641 tgaaaaacca taatttgaag aaattcaagt tcactctaaa tgcaacaatt tggttgtttg
     2701 cctttattgg atttaccttg ggttgcttgg gtgccctttc aatggatacc ttgttgaaac
     2761 tcgtagacta cattccaccg gtattgctta caggtttgac agttgctggt aaaatgctcc
     2821 cagctatcgg ttttgcgatg atcttgtcag tgatggctaa gaaagagttg attccctttg
     2881 tcttgttggg atatgtttgt gcagcttatc taaacatccc aacaattggt attgcaattg
     2941 taggtactat ctttgctttg attgaatttt ataacaagcc aaaaacagcg gatcatgtgg
     3001 tagaggagga agcacacgat gactggatct aacaaattaa caaaacgtga ttatcttaaa
     3061 acgtctttgc gggcattctt ttgtcaaaat ggatttaact atagtaacta tcaagggttg
     3121 ggatatgcca atgtgatgta tcctgctttg aaaaaacact atggagagaa tcaggaaggt
     3181 ttctaccaag ccttggaaga aaactgtgaa ttctataata ccaacccaca cttcctgcct
     3241 tttattacca gcttgcatct tgtaatgttg gaaaatggcc gtccggcaaa agaaacacgt
     3301 agcatcaaga tggccttgat gggaccatta gcaggtattg gggattctct ctctcaattc
     3361 tgtttagctc cattgttctc aaccatcgca gcttcgtttg ctcaagaagg cttggttgtc
     3421 ggtccaatct tgttcttcct tgcgatgaat acgattttaa cagcgattaa attgtcaact
     3481 ggtctgtatg gatacaaact aggaacgact gtgattgata aactaagcga gcagatggca
     3541 acgatttctc gtattgccaa tattattggt gtaaccgtaa ttgctggttt ggcagcgaca
     3601 tctgttaaga ttatggtacc gatcaccttt gctgcagggg aagttaaagc agacgctaaa
     3661 caaagtatcg taagtattca gggaatgctt gataaggttg ctccagctct tctaccagcc
     3721 ctatttacac ttttagttta ctacttgatc aaagaaaaga aatggacaac atataaactc
     3781 gttattttaa cagttatcat cggaattatc ggaagctggc ttaagattat agcttaatgg
     3841 atacaacatt gttttatgga atagtgattg tcttggcagt gagtcccctt ttactgtcaa
     3901 gctttcattc tattcgtcag caaaagttgc ttcgcaaaca gatggagcaa cgacaagagt
     3961 atttagcttc tttaacatct ggtgatgaag tgttgttatt gtctggaatt catggaaaaa
     4021 tcatttctat ccaagatgac ttggtctcct tgcagattgc aaaaggtgtg gtcatctatg
     4081 tagaaaagga aagtgtaatg ggaaagacaa aagaactgct ttttaagtag ttctttttct
     4141 ggtaatagat aatgaaagaa gaaagaagac aattttttga aagaatcgat ggaaaccaat
     4201 gtcgtgatta tatcttgtcc cactgttcaa aagactatga gaaagtcaag agttcccttg
     4261 aacgcttgat ggacaatcgt tttatgtttg atagtccttg ggatatggag ccttgttcaa
     4321 aaatccatca aatccagccg atggtatggg atcaagtatt tgaagatgat ccagaatggt
     4381 cttatatgct caatcgacaa gaatatctct tgcagtttat gatagggtat gtggtagaag
     4441 gagataagga ctatattcaa aagtgcaagt tctttctatt tgattggatt gagcaggtga
     4501 gagaattttc tcctcaatcc ttgatgacta gaaccttgga taccggtatt cgttccttta
     4561 cttggttgaa actactcttg ctcctcttga aatttgactt gctagaggag aaagaactag
     4621 agaaaatttt ggtcagtcta gaaaagcaga ttgactttat gaaaagccac tatcgcgcca
     4681 agtacaccct tagtaactgg ggaattttac aaacaattcc gatgcttgct atctatcatt
     4741 tctttgcaga taagatggac ctagaagaag cttaccattt tgcttcagag gagttgaaac
     4801 agcaaattga gacacagatt ttaggagatg gaagccagtt tgaacagtcg attctctatc
     4861 atgtagaggt ttataaagcc ttgctggatt tgtgtctctt gcttccagac ttgcaagata
     4921 gttaccaaga gttgctggaa aagatggcga cctatattca aatgatgaca ggcttagatg
     4981 gacgaacttt ggcttttggt gatagcgatt ctacagaaac gacagaaatg ttgagcctgt
     5041 ctgctgtggt tttgaacaag gaagaccttc ttaacggtct ggatgttaaa gtcgatttgc
     5101 ttagcctctt gttcctgggg cgagaaaagg tcaagcgact gcaggaattt gaaaagcgag
     5161 cttggcagcc taagttcatg agctttgaag actctggaca tgtctgcatt aaggatgaac
     5221 atcgttatct atttttcaaa aatggtccgc taggaagtgc ccatagccat agtgacgaga
     5281 atagtttttg cttacagtat caaggccaac ctattttcat agatgctggg cgttattctt
     5341 atcgggagat atatgaacgt tatctcttaa agagtgcttg gagtcattcg acctgcattg
     5401 tagatgggaa agctccggaa agaatcacgg gatcctggga atatgaatac tatcctcact
     5461 ccctgttttg tcaccataaa gaaagggagg gaatgcatta tattgaaggg gcttattggt
     5521 cagcagaacc tgatttgcct tatcttcaca ggagaaaaat cctcatgttg gtagaggatg
     5581 tctggctctt ggtagatgac atcaggtgtc aaggtcagca tgaggcgttg actcagttta
     5641 tccttgacaa ggatgtgacc tatcaagatg ggaaaatcaa tcagttgaga ctatggagtg
     5701 aagttgattt tgatttggaa gataccatca tttctcctaa atacaatgag cttgaaagaa
     5761 gtagcaaact caccaagcgc caattctttg agaatcagat gctggattat accatcattg
     5821 cgcatgagag ttttgaaatc atccgtcatt ctgtctacca gacagatgat cgtgaagtgg
     5881 aaaatgctct ggcttttgaa gtgaaaaatg acgaaacaga caagctgatt ctgttattaa
     5941 gcgaggatat ttgtgtaggt gaaaaattgt gcctcgttga cggaacaaaa atgcgtggaa
     6001 aatgtctagt atatgataaa ataaatgaga gaatgattcg cttgcagtgc tagaaatagg
     6061 cattttgaat agtgaatatg ttataataag tattagtagg aggtgtttta gattggagaa
     6121 gaaactgacc ataaaagaca ttgcggaaat ggctcagacc tcgaaaacaa ccgtgtcatt
     6181 ttacctaaac gggaaatatg aaaaaatgtc ccaagagaca cgtgaaaaga ttgaaaaagt
     6241 tattcatgaa acaaattaca aaccgagcat tgttgcgcgt agcttaaact ccaaacgaac
     6301 aaaattaatc ggtgttttga ttggtgatat taccaacagt ttctcaaacc aaattgttaa
     6361 gggaattgag gacatcgcca gccagaatgg ctaccaggta atgataggaa atagtaatta
     6421 cagccaagag agtgaggacc ggtatattga aagcatgctt ctcttgggag tagacggctt
     6481 tattattcag ccgacctcta atttccgaaa atattctcgt atcatcgatg agaaaaagaa
     6541 gaaaatggtc ttttttgata gtcagctcta tgaacaccgg actagctggg ttaaaaccaa
     6601 taactatgat gccgtttatg acatgaccca gtcctgtatc gaaaaaggtt atgaacattt
     6661 tctcttgatt acagcggata cgagtcgttt gagtactcgg attgagcggg caagtggttt
     6721 tgtggatgct ttaacagatg ctaatatgcg tcacgccagt ctaaccattg aagataagca
     6781 tacgaatttg gaacaaatta aggaattttt acaaaaagaa atcgatcccg atgaaaaaac
     6841 tctggtattt atccctaact gttgggccct acctctagtc tttaccgtta tcaaagagtt
     6901 gaattataac ttgccacaag ttgggttgat tggttttgac aatacggagt ggacttgctt
     6961 ttcttctcca agtgtttcga cgctggttca gccctccttt gaggaaggac aacaggctac
     7021 aaagattttg attgatcaga ttgaaggccg caatcaagaa gaaaggcaac aagtcttgga
     7081 ttgtagtgtg aattggaaag agtcgacttt ctaaaatgaa ggaaaatgac ttgcaatctc
     7141 tgttaagaaa taaaataatc ccacctagaa caagctaggt gggattattt gcctatgaaa
     7201 tgagaaatta tgggagcaag ctcctaaatc aactgttttt gatctacttc tttaactact
     7261 tgataaaagt tatagaagta ggccaaactt gaaatgatgg ttacgactag gaatattgaa
     7321 aatttccatt ggacagggtt ggttaaaagt tgtggaaagg atatgaggag aaagaagagg
     7381 gctgcgttga ggacaggtat ccgttttgat tgtattttct caagtccttt attgagcgca
     7441 ggaagaaaga ggagtaggag tagtaaaact gtatgagaaa cagctcctga aataagggca
     7501 aagaaaagga aaatactgat aaaaacatga atgatcagta gtctagctag tgatttcata
     7561 aggtacctcc taatcctggt cttttttagc tcttgcaata cgaagtgagt cgacaatatg
     7621 tatcatcact ccgaaaaaga aagctcccag tatagtttta aaaatatgtt ttgtatttag
     7681 aagagaactg ataaaatttg gattttcact tgttagggta tcaatgagtg gaattataaa
     7741 aaatatcact gttccataaa tcgaacctgc tttcagacca ggataacgta actgtttctt
     7801 ttcttttttc atgagtttgc tcctttttta aaaatcttcc tcccaaaaga gactgttgag
     7861 gtcagtttgg aggctgcggg cgagattgag acagagttcc aaggttggat tgtacttgtc
     7921 gttttcaatc atattgatag tctgtctcga gacaccgata tccttggcga gttcgagctg
     7981 ggaaataccc aattccttgc gaaattcttt cacacgattc atctggtctc ctttctgatt
     8041 tatgtcgtat atatttgact atattatagt cttttaaaca taaagtgtca agtatttttg
     8101 acatattttt tgaagaaata gtagtctcct tgtcctattt gtctgacaag tgcaagctgg
     8161 tcggatttgt ggtaaaatag ataagatatg acaaaagaat ttcatcatgt aacggtctta
     8221 ctccacgaaa cgattgatat gcttgacgta aagcctgaag gtatctacgt tgatgcgact
     8281 ttgggcggag caggacatag cgagtattta ttaagtaaat taagtgaaaa aggccatctc
     8341 tatgcctttg accaggatca gaatgccatt gacaatgcgc aaaaacgctt ggcaccttac
     8401 attgagaagg gaatggtgac ctttatcaag gataacttcc gtcatttaca ggcacgtttg
     8461 cgcgaagctg gtgttcagga aattgatgga atttgttatg acttgggagt gtctagtcct
     8521 caattggacc agcgtgagcg tggtttttct tataaaaagg atgcgccact ggacatgcgg
     8581 atgaatcagg atgctagtct gacagcctat gaagtggtta atcattatga ctatcatgat
     8641 ttggttcgta ttttcttcaa atacggtgag gataaattct ctaaacagat tgcgcgtaag
     8701 attgagcaag cgcgtgaagt gaagccgatt gagacaacga ctgagttagc agagattatc
     8761 aagttggtca aacctgccaa ggaactcaag aagaagggtc atcctgctaa gcagattttc
     8821 caggctattc gaattgaagt caatgatgaa ctgggagcgg cagatgagtc catccagcag
     8881 gctatggata tgttggctct ggatggtaga atttcagtga ttacctttca ttccttagaa
     8941 gaccgcttga ccaagcaatt gttcaaggaa gcttcaacag ttgaagttcc aaaaggcttg
     9001 cctttcatcc cagatgatct caagcccaag atggaattgg tgtcccgtaa gccaatcttg
     9061 ccaagtgcgg aagagttaga agccaataac cgctcgcact cagccaagtt gcgcgtggtc
     9121 agaaaaattc acaagtaaga gggaaaaaga tggcagaaaa aatggaaaaa acaggtcaaa
     9181 tactacagat gcaacttaaa cggttttcgc gtgtggaaaa agctttttac ttttccattg
     9241 ctgtaaccac tcttattgta gccattagta ttatttttat gcagaccaag ctcttgcaag
     9301 tgcagaatga tttgacaaaa atcaatgcgc agatagagga aaagaaaacc gaattggacg
     9361 atgccaagca agaggtcaat gaactattac gtgcagaacg tttgaaagaa attgccaatt
     9421 cacacgattt gcaattaaac aatgaaaata ttagaatagc ggagtaagat atgaagtgga
     9481 caaaaagagt aatccgttat gcgaccaaaa atcggaaatc gccggctgaa aacagacgca
     9541 gagttggaaa aagtctgagt ttattatctg tctttgtttt tgccattttt ttagtcaatt
     9601 ttgcggtcat tattgggaca ggcactcgct ttggaacaga tttagcgaag gaagctaaga
     9661 aggttcatca aaccacccgt acagttcctg ccaaacgtgg gactatttat gaccgaaatg
     9721 gagtcccgat tgctgaggat gcaacctctt ataatgtcta tgcggtcatt gatgagaact
     9781 ataagtcagc aacgggtaag attctttacg tagaaaaaac acaatttaac aaggttgcag
     9841 aggtctttca taagtatctg gacatggaag aatcctatgt aagagagcaa ctctcgcaac
     9901 ctaatctcaa gcaagtttcc tttggagcaa agggaaatgg gattacctat gccaatatga
     9961 tgtctatcaa aaaagaattg gaagctgcag aggtcaaggg gattgatttt acaaccagtc
    10021 ccaatcgtag ttacccaaac ggacaatttg cttctagttt tatcggccta gctcagctcc
    10081 atgaaaatga agatggaagc aagagcttgc tgggaacctc tggaatggag agttccttga
    10141 acagtattct tgcagggaca gacggcatta ttacctatga aaaggatcgt ctgggtaata
    10201 ttgtacccgg aacagaacaa gtttcccaac gaacgatgga cggtaaggat gtttatacaa
    10261 ccatttccag ccccctccag tcctttatgg aaacccagat ggatgctttt caagagaagg
    10321 taaaaggaaa gtacatgaca gcgactttgg tcagtgctaa aacaggggaa attctggcaa
    10381 caacgcaacg accgaccttt gatgcagata caaaagaagg cattacagag gactttgttt
    10441 ggcgtgatat cctttaccaa agtaactatg agccaggttc cactatgaaa gtgatgatgt
    10501 tggctgctgc tattgataat aatacctttc caggaggaga agtctttaat agtagtgagt
    10561 taaaaattgc agatgccacg attcgagatt gggacgttaa tgaaggattg actggtggca
    10621 gaatgatgac tttttctcaa ggttttgcac actcaagtaa cgttgggatg accctccttg
    10681 agcaaaagat gggagatgct acctggcttg attatcttaa tcgttttaaa tttggtgttc
    10741 cgacccgttt cggtttgacg gatgagtatg ctggtcagct tcctgcggat aatattgtca
    10801 acattgcgca aagctcattt ggacaaggga tttcagtgac ccagacgcaa atgattcgtg
    10861 cctttacagc tattgctaat gacggtgtca tgctggagcc taaatttatt agtgccattt
    10921 atgatccaaa tgatcaaact gctcggaaat ctcaaaaaga aattgtggga aatcctgttt
    10981 ctaaagatgc agctagtcta actcggacta acatggtttt ggtagggacg gatccggttt
    11041 atggaaccat gtataaccac agcacaggca agccaactgt aactgttcct gggcaaaatg
    11101 tagccctcaa gtctggtacg gctcagattg ctgacgagaa aaatggtggt tatctagtcg
    11161 gggtaaccga ctatattttc tcggctgtat cgatgagtcc ggctgaaaat cctgatttta
    11221 tcttgtatgt gacggtccaa caacctgaac attattcagg tattcagttg ggagaatttg
    11281 ccaatcctat cttggagcgg gcttcagcta tgaaagactc tctcaatctt caaacaacag
    11341 ctaaagcttt ggagcaagta agtcaacaaa gtccttatcc tatgcctagt gtcaaggata
    11401 tttcacctgg tgatttagca gaagaattgc gtcgcaatct tgtacaaccc atcgttgtgg
    11461 gaacaggaac gaagattaaa aacagttctg ctgaagaagg gaagaatctt gccccgaacc
    11521 agcaagtcct tatcttatct gataaagtag aggaagttcc ggatatgtat ggttggacaa
    11581 aggagactgc tgagaccctt gctaagtggc tcaatataga acttgaattt caaggttcgg
    11641 gctctactgt gcagaagcaa gatgttcgtg ctaacacagc tatcaaggac attaaaaaaa
    11701 ttacattaac tttaggagac taatatgttt atttccctca gtgctggaat tgtgacattt
    11761 ttactaactt tagtaggaat tccggccttt atccaatttt atagaaaggc gcaaattaca
    11821 ggccagcaga tgcatgagga tgtcaaacag catcaggcaa aagctgggac tcctacaatg
    11881 ggaggtttgg ttttcttgat tacttctgtt ttggttgctt tctttttcgc cctatttagt
    11941 agccaattca gcaataatgt gggaatgatt ttgttcatct tggtcttgta tggcttggtc
    12001 ggatttttag atgactttct caaggtcttt cgtaaaatca atgaggggct taatcctaag
    12061 caaaaattag ctcttcagct tctaggtgga gttatcttct atcttttcta tgagcgcggt
    12121 ggcgatatgc tttctgtctt tggttatcaa gtgcatctag ggattttcta tattgtcttc
    12181 gctcttttct ggctagtcgg tttttcaaac gcagtaaact tgacagacgg tgttgacggt
    12241 ttagctagta tttccgttgt gattagtttg tctgcctatg gagttattgc ctatgtgcaa
    12301 ggtcagatgg atattcttct agtgattctt gccatgattg gtggtttgct cggtttcttc
    12361 atctttaacc ataagcctgc caaggtcttt atgggtgatg tgggaagttt ggccctaggt
    12421 gggatgctgg cagctatctc tatggctctc caccaagaat ggactctctt gattatcgga
    12481 attgtatatg tttttgaaac aacttctgtt atgatgcaag tcagttattt caaactgaca
    12541 ggtggtaaac gtattttccg tatgacgcct gtacatcacc attttgagct tgggggattg
    12601 tctggtaaag gaaatccttg gagcgagtgg aaggttgact tcttcttttg gggagtggga
    12661 cttctagcaa gtctcctgac cctcgcaatt ttatatttga tgtaagaatg gcaccctgat
    12721 gtttcagggt gtttttgtgt ttaaatacac aatgaaaatc aaagaacaaa ctagaaagct
    12781 aactttaggc tgctcaaaat atagtagatt gaaactagaa tagtacacat ctacttctaa
    12841 aatattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt
    12901 aatatacagt tttgaggttg tagataagga gaagctgatg tggtttgaag aggttttcga
    12961 agagtgtaaa aaaatattgg tcagttaaag tcaaaactct tgaccttttc tgactaatgt
    13021 agtatattat gaacgtaagg taaatgaaag ccttactaga acacttattt aaagtaaaat
    13081 agaaagaggt gggtctatgt ttcatctaga aatcttcaga agtaaagata gtctactcct
    13141 gcttgaaaaa gaaaaaccag aaatagtacg tagggtagcg atctagctag tctaaatttt
    13201 ttaaaacaat ggtcaaagat agtcaatatc agtaatcata actaagtaaa caaaaagagg
    13261 taaagaatat gaataacaac tttaataatt ttaataacat ggatgattta tttaaccaat
    13321 tgatgggtgg tatgcgagga tacagttctg aaaatcgccg ttacttaatt aatggacgcg
    13381 aagtcacacc tgaggaattt gctcactatc gtacgactgg tcaattacca ggaaatgcag
    13441 aaactgatgt gcaaatgcca caacaggcat caggtatgaa acaagacggt gtccttgcaa
    13501 aactaggtcg aaacttgaca gcagaagcgc gtgagggcaa gttggatcct gttatcggac
    13561 gaaacaagga aattcaagaa acatctgaaa tcctctcacg ccgcaccaag aacaatcctg
    13621 ttttggtcgg agatgcaggt gttggtaaga cagcagttgt cgaaggtcta gcgcaagcca
    13681 ttgtgaacgg agatgttcct gctgctatca agaacaagga aattatttct attgatatct
    13741 caggtcttga ggctggtact caataccgtg gtagctttga agaaaatgtc caaaacttag
    13801 tcaatgaagt gaaagaagca gggaatatta tcctcttctt tgatgaaatt caccaaattc
    13861 ttggtgctgg tagcactggt ggagacagtg gttctaaagg gcttgcggat attctcaagc
    13921 cagctctctc tcgtggagaa ttgacagtga ttggggcaac aactcaagac gaataccgta
    13981 acaccatctt gaagaatgct gctcttgctc gtcgtttcaa cgaagtgaag gtcaatgctc
    14041 cttcagcaga gaatactttt aaaattcttc aaggcattcg tgacctctat caacaacacc
    14101 acaatgtcat cttgccagac gaagtcttga aagcagcggt ggattattct gttcaataca
    14161 ttcctcaacg tagcttgcca gataaggcta ttgaccttgt cgatgtaacg gctgctcact
    14221 tggcggctca acatccagta acagatgtgc atgctgttga acgagaaatc gaaacggaaa
    14281 aagacaagca agaaaaagca gttgaagcag aagattttga agcagctcta aactataaaa
    14341 cacgcattgc agaattggaa aagaaaatcg aaaaccacac agaagatatg aaagtgactg
    14401 caagtgtcaa cgatgtggct gaatctgtgg aacgaatgac aggtatccca gtatcgcaaa
    14461 tgggagcttc agatatcgaa cgtttgaaag atatggctca tcgcttgcaa gacaaggtga
    14521 ttggtcaaga taaggccgta gaagctgtag ctcgtgctat ccgtcgtaac cgtgctggtt
    14581 ttgatgaagg aaatcgccca atcggcagct tcctctttgt agggtctact ggggttggta
    14641 agacggagct tgctaagcaa ttggcactcg atatgtttgg aacccaggat gcgattatcc
    14701 gtttggatat gtctgaatac agtgaccgca cagctgtttc taagctaatt ggtacaacag
    14761 caggctatgt gggttatgat gacaatagca ataccttaac agaacgtgtt cgtcgcaatc
    14821 catactctat cattctcttg gatgaaattg aaaaggctga tcctcaagtt attacccttc
    14881 tcctccaagt tctagatgat ggtcgtttga cagatggtca aggaaataca gtaaacttca
    14941 agaacactgt cattattgcg acctcaaatg ctggatttgg ctatgaagcc aacttgacag
    15001 aagatgcgga taaaccagaa ttgatggacc gtttgaaacc cttcttccgt ccagaattcc
    15061 tcaaccgctt taatgcagtc atcgagtttt cacacttgac taaggaagac ctttctaaga
    15121 ttgtagattt gatgttggct gaagttaacc aaaccttggc taagaaagac attgacttgg
    15181 tagtcagtca agcggctaaa gattatatca cagaagaagg ttacgacgaa gtcatggggg
    15241 ttcgtcctct ccgtcgcgtg gttgaacaag aaattcgtga taaggtgaca gacttccact
    15301 tggatcattt agatgctaaa catctggaag cagatatgga agatggcgtt ttggttattc
    15361 gtgagaaagc ctaagacaga attttgagaa taaaaaagaa ggagccagct gaaaaaaact
    15421 ggttcctttt gaggtacgac gggcatgtcg tgtagtagag atgtactatt ctagtttcaa
    15481 tctactatag tagctcagaa atcggtactt aaacgtgcta tatcaaaacc agtccttgaa
    15541 aaacgtggac tggtttcgtg tttggattat tactttgaac gacatgcgtt aaaagttagt
    15601 tgaaccgccg tatgccgaac ggtacgtacg gtggtgtgag aggggctaga gattatcccc
    15661 tactcgattt taaatcacat gacgttcaaa ggcatcatct gaaatccctt gttccaagat
    15721 gagttttgcc cattctttag cagagaagag gctgtggtcc ttgtagtttc cgcaagattc
    15781 gatggttgtc cctgggacat cttcccaagt agtagtttca gcgatttcct tgagcgaatc
    15841 cttgataaca gctgcgattt tagcactggt gtgacgtccc cacataatca tgtggaagcc
    15901 tgtgcggcaa ccaaatggcg aacagtcaat catgccgtca atgcgggtac ggatgagttt
    15961 ggctaagagg tgctcgatag tgtgaaggcc ggcggtaggg atagagtctt cgtttggttg
    16021 caccaagcga atatcataat tggagatgat gtctcctttt ggtcctgttt cttccccaat
    16081 caagcgaaca tagggtgctt tgacaatggt gtggtcaagt tcaaaacttt cgacaataac
    16141 ttcttttgac atggtaaatc ctttcagttt tcttctctca ttatatcata aaggttgctc
    16201 ctgagacaga gagaaaacct ctccgaggct ggagaggttg aaatctttac ttacgatata
    16261 agcggtcgta ttggtagtat gggtcaaagg ttacgttgat acccagttta cgaaggacat
    16321 tcttgtcttc atcagtcaag atgatggttg agtgggcttc gcttcctttg aggttgccga
    16381 gttcttccat agcgcgggta gcatcaggat tttctgtagc tgtgatagca agtgcaatca
    16441 ggatttcatt tgaatgaagg cgtggattgc ggctaccgag atgatcgatt ttaagacctt
    16501 ggattggctt aacaacttcc ggctcgatta attttacttc tttagcgatg tcagctgatt
    16561 ttttgatggc gttgatcaag gcagcggctg tagggccaaa gagttctgag ttcttaccag
    16621 tgacgatttc cccatttggc aattcaaagg ctagggctgg tccaccagtt tcttctgctt
    16681 tttggcgcgc aacgacagca accttacggt ctgcaggtgt gataccgagg tcgttcatga
    16741 gcaactcaat tttcttgacg gcagcttcgc caactttttc agctttgaag tcaagaactg
    16801 tttgatagta acggcggatg atttcttgtt tagaagcttc gacagcggcc tcgtcatctg
    16861 taatagcgaa accaaccatg ttgacaccca tatctgtcgg tgaagcgtat ggtgattttc
    16921 cgagaatacg ttccaacatg cgtttgagca ctgggaagat ttcgatatca cggttgtagt
    16981 tgacagtggt ttctccatag gtttggagat ggaaggggtc aatcatgttg acatcatcaa
    17041 ggtcagctgt ggcagcttca taagccaagt taactggatg atgaagggga agattccaaa
    17101 cagggaaggt ttcaaattta gcgtagccag atttgatgcc attgatttgg tcgtggtaca
    17161 tattggacat acacgttgcc aattttccag aaccaggtcc aggagcggtt acgacaatca
    17221 agttgcgact ggttttgatg tagtcgtttt tgcccatgcc ttctggggaa atgatgtgat
    17281 ccatatccgt cggatatcct ttgattggat aatgaagata tgaatcaatt ccgtttttct
    17341 caagttggtt gcggaaggca tctgcagcgg gttggccagc gtattgtgta atgacaacgg
    17401 aaccaacaaa aatccccaat tcattgaatt tgtcaatcaa acgaagaact tcttggtcat
    17461 aagaaatgcc taagtcgcca cgtgctttgg aatgttcaat gttgctagca ttaatggcaa
    17521 tcacaacctc aacctgctct ttcaattctt gcaagagctt gattttgttg tcaggttcat
    17581 aaccaggaag gacacgagca gcgtggaaat cttctaacat tttaccgcca aactctaagt
    17641 agagcttgcc gtcaaattgg ttaatacgct ccaaaatatg gtcgcgttgt aaattcaaat
    17701 attgttcaga actaaaagct tgttttttca tttttttacc tctggactct attataataa
    17761 aaaattggaa gttaggaaac tacggagcta aaaaagaaat taaaaagatt aagcaaacgc
    17821 ttgcacaaaa ttttaaaaag tgctatcata gactatagat tattaaaata atgaggtaaa
    17881 cagatgcaag aaaaatggtg gcataatgcc gtagtctatc aagtctatcc aaagagtttt
    17941 atggatagta atggagatgg agttggtgat ttgccaggta ttaccagtaa gttggactat
    18001 ctagccaagc taggaatcac agcaatttgg ctttctcccg tttatgacag ccctatggat
    18061 gataatggtt acgatattgc tgattatcaa gcgattgcaa cgatttttgg aaccatggag
    18121 gatatggatc aactgattgc agaagctaag aagcgtgata tccgtatcat catggacttg
    18181 gtggtcaatc atacctcgga tgagcatgcc tggtttgtag aggcctgtga aaatcctaat
    18241 agccctgagc gagactacta tatctggcgc gatgaaccca atgacctaga ttctatcttt
    18301 agtgggtctg cttgggaata cgatgaaaag tcaggtcaat actatctcca ctttttcagc
    18361 aagaaacagc cggatctcaa ctgggaaaat gaaaaacttc gccagaaaat ttatgagatg
    18421 atgaacttct ggattgataa aggtattggt ggtttccgta tggatgttat tgacatgatt
    18481 ggcaaaattc ctgacgagaa ggtagtcaat aatggtccta tgctccatcc ctatctcaag
    18541 gaaatgaatc aggcgacctt tggagataag gatctcttga cagtagggga gacttgggga
    18601 gcaacgccag agattgccaa gctctactct gatccaaagg ggcaagaatt gtctatggtc
    18661 ttccagtttg aacatatcgg tcttcagtat caggaaggtc agcctaaatg gcactatcaa
    18721 aaagagctga atatcgctaa gttaaaagaa atcttcaaca aatggcagac agagttagga
    18781 gttgaggacg gctggaattc cctcttctgg aacaaccatg acctccctcg tattgtctca
    18841 atatggggaa atgaccaaga ataccgcgaa aaatctgcca aagcctttgc aatcttgctt
    18901 catcttatga gaggaactcc ttatatctac caaggtgagg agattgggat gaccaactat
    18961 ccgtttgaaa cactagatca agtagaagat attgaatctc tcaactatgc gcgtgaggct
    19021 cttgaaaaag gtgttccgat tgaagaaatc atggacagta tccgtgttat tggacgtgac
    19081 aatgcccgta cccctatgca atgggacgag agcaaaaacg ctggtttctc aacaggtcaa
    19141 ccttggttgg cggttaatcc aaattacgag atgatcaacg tccaagaagc gctggcaaat
    19201 ccagattcta ttttctatac ctatcagaaa ctggtccaaa ttcgcaagga gaatagctgg
    19261 ctagttcgag ctgactttga attgcttgat acggctgata aggtctttgc ttatatacgt
    19321 aaggatggcg accgtcgctt cctagttgtg gctaacttgt ccaatgaaga gcaagacttg
    19381 acagtagaag gaaaagtcaa atctgtcttg attgaaaaca ccctagctca agaagtcttt
    19441 gaaaaacaaa tcttagttcc atgggatgct ttctgtgtgg aaatgactga ctagaatgag
    19501 caaacctcaa gtttttgaag cttgaggttt tttactatag tggattgaaa ctagaatagt
    19561 gcacctctgc ttctaaaaca ttgttagaaa tcgatttgac tgtcccgatc gatttgtcct
    19621 attcttattt cattttgcta tacttgtagt tgaggagaat taagctcctc actagtaaac
    19681 tcttcataat cctttttatt tttatgaaga tattgtttga aagatgtgag tttccacgga
    19741 tgggtttgtg gagggatata cttgcgtctt tctttttttg ttctggttct tgttcaaagt
    19801 ttttcgaata gagttcatga tttagtagct cctttgtgtg atagattttg tcagcgatat
    19861 tgaggtagat gtctccgtca aatgctttta taactaatgc tttcgtcttt ctgatgaaat
    19921 agacttcttt tccttgttcg gtagggatat agtaacgatt ttggaatcgg atatggtgtc
    19981 cactatcgac gactctctcc gccagtctag ccagaatgag attcctttca gaggggttag
    20041 gaacctcctc gaagacagag agttttgtct tgtttccaaa ctgttcatta aaggtttgaa
    20101 tgtaggaaag caggaaggta ttggcttctt ccaaggtatg aatattgttt tgttccagtt
    20161 cgataggcag gcgagattgt agtgtctgat tgagtctttc gactctccct ttagcttgag
    20221 ggatagaggt tgtctcaagg agaatcccta gttggtgaca ggcgtatcca aactgtgtat
    20281 gggtatcgtc ctccattttc ttagagttgg aggcttgata ggtaaagacc gttctcttat
    20341 ctgttttaat ttgaagggga atgccgtgat tggctaagat ttgttcgagg acatgatagt
    20401 aagcattcaa gttctcttgt ttatcaaaat aagcgcctag gatattgcca gaagcatcat
    20461 caatggctaa gtgtaagtta gatgtttggg ctccaaacta ggcatgaggg ctggcatcca
    20521 tttgaatgag ttcaccagca aatttctttc tgggtctact aggatgtact tttttagggt
    20581 cttcaaggaa gttttcagcc gtcggtaaga ttggattgtc taggggttga ttcaggttca
    20641 gtttagcttg ttttcttact ctcttctttg tctttctatg ggacttaggc gacaggatat
    20701 ttttcttata gagtattttt ctaacagtag tatcagagag ctgaattcct tcttcttcag
    20761 ctagcaattc acagaaatga aggacatttg gtttatatgt ttcataggag aggtattttt
    20821 ttaggagacg ttctttgatt tcatcaggga ttgcatgttt tggttttcga tttctgtttc
    20881 cgtgtctgaa ggcttctttt cctttcagtt gataggctag tagcagacga ttgatttgtc
    20941 tttcagaaag attgagctcg acacaggctc gtttctttgt tttctttcct tgggctatag
    21001 cttttatcac aagatatttt ttcgtttcat tcatattcag ttggatcctt ttcatatgac
    21061 tattctacca aatgggacat tttcacgttc gatttactaa agacattatc acattcgaat
    21121 tacacaagat gcagatagtg aaaataaagg tgtagacatt accgtaaaaa agtgatataa
    21181 ttgtatgatg ttcaatgtat aggtgttaat catgagtaga cgttttaaaa aatcaggttc
    21241 acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat tgttagtttg
    21301 ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc ttaatctagt
    21361 ggtaactgcg ttagtcctac tagttgcctt agtagggcta ctcttgatta tctataaaaa
    21421 agctgaaaag tttactattt ttctgttggt gttctctatc cttgtcagct ctgtgtcgct
    21481 ttttgcagta cagcagtttg ttggactgac caatcgttta aatgcgactt cgaattactc
    21541 agaatattca atcagtgtcg ctgttttagc agatagtgag atcgaaaatg ttacgcaact
    21601 gacgagtgtg acagcaccga ctgggactga taatgaaaat attcaaaaac tactagctga
    21661 tatcaagtca agtcagaata ccgatttgac ggtcaaccag agttcgtctt acttggcagc
    21721 ttacaagagt ttgattgcag gggagactaa ggccattgtc ctaaatagtg tctttgaaaa
    21781 tatcatcgag tcagagtatc cagactacgc atcgaagata aaaaagattt ataccaaggg
    21841 attcactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca atatctatgt
    21901 tagtggaatt gacacctatg gtcctattag ttcggtgtcg cgatcagatg tcaatatcct
    21961 gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccac gtgatgccta
    22021 tgtaccaatc gcagatggtg gaaataatca aaaagataaa ttaacccatg cgggcattta
    22081 tggagttgat tcgtccattc ataccctaga gaacctttat ggtgtagata ttaattatta
    22141 tgttcgtttg aattttacct catttttgaa attgattgac ttattgggag gggtagatgt
    22201 tcataatgat caagagtttt cagctctaca taggaagttc cttttcccag tagggaatgt
    22261 ccatctagac tctgagcagg ctctaggttt tgtacgtgaa cgctactcac tagccgatgg
    22321 agaccgtgac cgtggtcgca accaacaaaa ggtgattgtg gctattcttc aaaaattaac
    22381 gtcaaccgaa gcactgaaaa attatagtac gatcattaat agcttgcaag attctatcca
    22441 aacaaatatg ccacttgaga ctatgataaa tttggtcaat gctcagttag aaagtggtgg
    22501 aacttacaaa gtgaattctc aagatttaaa agggacagat cggatggatc ttccttctta
    22561 tgcaatgcct gacagtaacc tctatgtgat ggaaatagat gatagtagtt tagctgtagt
    22621 taaagcagct atacaggatg tgatggaggg tagatgaaat gatagacatc cattcgcata
    22681 tcgtttttga tgtagatgac ggtcccaagt caatagagga aagcaaggca cttttaagag
    22741 aagcttataa tcaaggagtt cgaatgattg tgtctacttc gcatcgtcga aaagggatgt
    22801 ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa attgcaaaag
    22861 aagtagcaga tgatttagtc atagcttatg gcgcagagat atactatact ctggatgctc
    22921 tagaaaagct agaaaaaaaa gaaattccta cccttaatga tagtcgttat gctttgattg
    22981 agtttagcat gcatacttcc tatcgtgaga ttcatgcggg attgagcaat attttgatgt
    23041 tgggaatcac gccagtaatt gctcatattg aacgttatga tgccttagag aataacgaaa
    23101 aacgtgttcg tgaactgatt gatatggggt gctatactca gataaatagt tatcatgttt
    23161 taaaacctaa gttctttggt gaaaaatata aattcatgaa aaagagagct cggtattttt
    23221 tggaacgtga tttagttcat gtagttgcaa gtgacatgca caatttagac agtagacctc
    23281 catatatgca acaggcatat gatatcattg ctaagaaata tggagcgaaa aaagcgaaag
    23341 aattttttgt agataatccc agaaaaatta taatggatca attaatttag gagaaaatat
    23401 gaaggaacaa aacactttgg aaatcgatgt attgcaacta ttcagggctt tatggaaaag
    23461 aaagttggtc attttattag tggcaattat aacttcttca gttgcttttg cctacagtac
    23521 ttttgttatc aaacctgagt ttactagtac gactcggatt tatgtagtta accgtaatca
    23581 ggaagagaag tctggtttaa ccaatcaaga cttgcaggca ggatcatact tggttaaaga
    23641 ctatcgtgaa attatcctat cgcaggatgt tttggaggaa gttatttctg atttgaaact
    23701 agatttgacg ccaaaaggtt tggctaataa aattaaagta acagtaccag ttgatacccg
    23761 tattgtctct gtctcagtta atgatcgagt tcctgaagag gcaagccgta tcgctaactc
    23821 tttgagagaa gtagctgctc aaaaaattat cagtattact cgtgtttctg atgtgacaac
    23881 actggaggag gcaagaccgg cgatatcacc atcttcgcca aatattaaac gcaatacact
    23941 aattggtttt ttggcagggg ggattggaac tagtgttata gttcttcttc ttgaactttt
    24001 ggacactcat gtgaaacgtc cggaagatat cgaagataca ctgcagatga cacttttggg
    24061 agttgtacca aacttgagta agttgaaata ggagagagga atgccgacat tagaaatagc
    24121 acaaaaaaaa ctggagttca ttaagaaggc agaagaatat tacaatgcct tgtgtacaaa
    24181 tatacagttg agcggagata aactaaaagt aatttccgtt acttctgtta accctgggga
    24241 aggaaaaaca actacttccg taaatatagc aaggtcgttt gcgcgtacag gctataaaac
    24301 tcttttgatc gatggcgata ctcgaaattc agttatatca ggagttttta aatcgcgtga
    24361 aaaaattaca gggctaacag aatttttatc tgggacagct gatttatctc acggtttatg
    24421 tgatacaaat attgaaaatt tatttgtaat tcaatcggga tctgtatcac caaaccctac
    24481 agccttgtta caaagtaaaa attttaatga tatgattgaa acattgcgta aatattttga
    24541 ttatatcatt gttgatacag cacctattgg aattgttatt gatgcggcaa ttatcactca
    24601 aaagtgtgat gcgtccatct tggtaacagc aataggtgag gtgaataaac gtgatgtcca
    24661 aaaagcgaaa caacaattag aacaaacaga gaaactgttc ctaggagttg ttttaaataa
    24721 attggatatc tcggttgata agtatggagt ttacggttcc tatggaaatt atggtaaaaa
    24781 ataacttagg aaagatttta tggatgaaaa aggattgaaa atttttctag cagtaataca
    24841 gagtattatt gtcattttat tggtttattt tcttagcttt gttagagaga cagaacttga
    24901 acgttcttcg atggttatac tataccttct ccactttttt gtattctatt ttagttccta
    24961 tggtaacaat ttttttaaaa gagggtacct agttgagttt aatagtacta taagatatat
    25021 ttttttcttt gcaatagcta taagtgtatt aaactttttt atagcggaac ggtttagtat
    25081 ctctagaaga ggaatggtat acttcttaac tttagaagga atatccttat acttgttaaa
    25141 tttcttagta aagaaatatt ggaagcatgt gttttttaat ctaaaaaata gcaagaaaat
    25201 tttactgtta acagtaacga aaaatatgga aaaagttctt gataaattgc tagaatctga
    25261 tgaactttca tggaaattgg tagcagtaag tgttttggat aaatctgatt ttcaacatga
    25321 taaaatacct gtaattgaaa aggaaaaaat tattgaattt gcaacgcatg aagttgtgga
    25381 tgaggtgttt gtcaatcttc caggagagag ctacgatatt ggagaaatta tctctaggtt
    25441 tgagacaatg gggatagatg taactgtaaa tcttaaagca tttgataaga atttgggtcg
    25501 caataaacaa attcatgaga tggtaggatt gaatgtagtc actttctcta caaattttta
    25561 taaaactagt catgtgattt caaagagaat tctcgatatt tgtggtgcca ctattggcct
    25621 tattcttttt gctatagcta gtctagtttt agttccattg attcgtaaag atggcggatc
    25681 agctattttt gctcaaactc gtatagggaa aaatggtcga cattttacct tttataaatt
    25741 ccgttcgatg cgaatcgatg ctgaagctat caaagaacag ttgatggatc aaaatacgat
    25801 gcaaggtggt atgtttaaga tagacaatga tcctcgtgtt acaaaaattg gtcgctttat
    25861 tcgtaaaact agtttagatg aattgccgca gttttggaat gtctttatag gagatatgag
    25921 tttggtggga acacgtccac ctacagtaga cgagtatgat cagtatactc cagaacagaa
    25981 acgtcgactc agctttaaac ctggtattac aggtttatgg caggttagcg gccgtagtaa
    26041 aataaccgat tttgacgatg ttgtaaaatt agatgtggct tatattgata attggacaat
    26101 ctggaaagat attgaaattt tgcttaaaac tgttaaagtt gtatttatga gagatggagc
    26161 gaagtaattc atatgaatga gagaatgcaa atattaggag ttactataga tccattaacg
    26221 atgaaagaaa cagtggatgc tgttgaacag tatgttttaa agaagcatcc tttgcacttg
    26281 atgggagtta acgcagataa aattaatcag tgccatgaag atgagaaaat caaaaaaatc
    26341 gttaatgaat caggaatcat taatgcggat ggagcatcag ttgttcttgc aagtaagttt
    26401 ttaggaacgc ctgttcctga acgagtagcg ggtattgatt tgatgcaatg tcttttagag
    26461 ttgtcaaata aaaaaggata ttcagtttac ttttttggag ctaaagaaga aattttacaa
    26521 gatatgctaa aagtttttaa acaaagatat cctaatctta atgttgttgg ctatagaaac
    26581 ggatattttt cacctgaaga tgaaaaaaag attcaggaag atattaaagg aggaaaacca
    26641 gattttgtat ttgtagggat tacttctcct aaaaaggagt atatcatcca atcattcatg
    26701 gataatggga ttaatgctgt ctttatgggt gttggtggca gttttgatgt attatcagga
    26761 cacattaaac gagctccatt atggatgcaa aaattgaatc tggaatggtt gttccgtgta
    26821 gttaatgaac ccaaacgcct ttttaagcgt tattttatag ggaatgttac ttttattaag
    26881 cgagttttag atgaaaagcg aaaatcaaaa aaataatatt ctacatattt ctcgtacaat
    26941 ggatattggt ggtgcagaac gtattgtata tcaattgagt tctgatttga aagatgaatt
    27001 tgatagtgtc catgtcgctt caacaggtgg actatgggag agcaaacttt tatcaaaagg
    27061 agttcaacat cataaaattt tagatgttga cagtaagaat cccctaacta tggtaaagat
    27121 cctttcaagt ttttatagaa ttatcaaaaa taatgatatt accattgttc acactcatca
    27181 tcggatggct gccttttata ttcgcttgtt gaaaatcatt aatcctaagt tgatacatgt
    27241 ttacactgca cataatgtat ttaaaaataa attaccatta tacaaatttt ccttaaaaaa
    27301 agcgtattgt gtagctgtaa gtaaagcggt taatgataat ttgaaacatg atgtaggaat
    27361 cagtgatagt acagtaatct ataatggggt tgtttttgaa aaaactgata agctagttgg
    27421 tgaaattgta aactataacg gaatcaaatt ggggtgtatt gctaggttat cagagcaaaa
    27481 aggattgacc tacctaattg atgcgatgtc tttagtgaaa cacaggaata ttacgttgtt
    27541 cattgtcgga gatggagagc ttcgagatga gcttgaaaac aaggtgaaac aattaaatct
    27601 tcaaaaatca gtgatatttt taggttatcg aaaagatatt gttgaatgta tcaatagttt
    27661 tgattactta gtgtcatcat ctttatatga ggggtttggt ctaaatgcaa ttgaagcatt
    27721 tatgaagggg aaaacgatgg tttcatcaga tatcccagga ataaatgaag tagtcaataa
    27781 caaaaatggg attcttgttc ctgttaagga tgatgttgcc ttagcgagag cgattgaaaa
    27841 gcttgcgact gacaaaaaac ttagagaaaa actcgcttat caagcaaaaa aagattatga
    27901 gacaaaattt aattattcct tgtttttgga taattatcgg agactttata gaaaattaat
    27961 gggagaatca aaatgaaaaa agtcatgttg gtttttggga cacgtccaga agctattaaa
    28021 atgtgtcctt tagtaaatga actgaaacaa aatgattcaa tcaagacact tgtgtgtgta
    28081 actggtcaac ataaggaaat gttagagcag gttttagagg tgttcaaggt tgtcccagat
    28141 tatgatttgg gtatcatgaa agcaaatcag accctattta ccattacgac tagtatcttg
    28201 gataaaattc aggcggttct agagaaagaa aaaccagatc ttgttcttgt tcatggagat
    28261 actacaacaa catttgcgac agctttagca gcattttata tgggaatcaa agtgggacac
    28321 gtcgaagcag gtctcagaac ctataatctc caaagtccat ttccagagga attcaatcgc
    28381 cagacaactt ctatcattgc cgactatcat tttgcgccga ctgaagttgc gaaggaaaat
    28441 ctactaagag aggacagaaa aaatatcttt gtgacgggaa atacagtcat tgatgctttg
    28501 aagacgactg ttcaagataa ctaccatcac ccaattttag aatgggcaaa gggtagtaag
    28561 ttaatcatgc taacggctca tcgacgagaa aatcttggga aaccgatgga aaacatgttt
    28621 aatgctgtta atcgaatttt aaacgaattc gaagatgtaa aagttgtata tcccatccat
    28681 aaaaatccta aggttcgaga attagcaagt aaagtttttg gcgataatga acgaatgaaa
    28741 atcattgaac cgttagaggt tattgatttt cataatttta tgaatcaaag ctatatgatt
    28801 ttgacagatt ctggaggtgt acaggaagaa gcaccttctt taggaaaacc tgtcttggtg
    28861 atgcgtgata caacagagcg tcctgagggg gtcgttgctg gcacgttgaa gttggtagga
    28921 acagaagaag agaatatcta tagcaacttc aaacttcttc ttgaagatga aacagaatat
    28981 aacaagatga gcaaagctag caacccttat ggagatggaa tgacttgtaa acggattgtt
    29041 gatattattc tggaagtata aaaataattc aattatggat gaggaaagaa taaattagat
    29101 tgatgataaa aagaaaaata tatataatct gtgtattact gtcgtatttt ttacctagtt
    29161 tttttacagt tggatcaatg gcgactttat ttgctttgct ttctacttta gttaagctat
    29221 ttgtaacttt tgattatatt cccaaagttc ttttacagca taaagtaaca ctgattgata
    29281 ttctagttgt tctattttta ttttttcaag catttgcagc ttttcaaagc caaacgttgt
    29341 accttaacta tgttggaggt cagtttttcc ttttaggact atattcattt ttgaaacact
    29401 ttttattgtt ggattgtaaa acaacaataa aaagcctctt tttaaccttt atcttgtttt
    29461 tgtgtgttca agtaataact caattgcttt ttccggtcgg tttcgattct ttgcacccta
    29521 caggagataa tagactttac tttttaggaa gaaagaacat agctaccccg tatatcattg
    29581 ttggattagg tggtttttac ttattaaata aaaaaatgaa tgagtttata tcactaaagg
    29641 agattatttt tttaggattg ttcggaattt tatcattttt aacacaatcc agtacagcga
    29701 ttatatgtta tgggcttttt attttcatac gtctattggg attaaaggaa aatataggaa
    29761 aactatattc tttagtcagt atggctgtat atgtttgttt ttctctttct ataatctttt
    29821 cacaaagtac aattttatca acttttacag cgattttttc caaaaatgca actttttcag
    29881 gacgtatcaa tatttggcaa ttagcgattc gtatttttga agagaatttt tggtttggac
    29941 gaggcctcaa cgttaatttt aatgcttgga caaatgggat tatcgttaat tcagcacaca
    30001 ataccttatt agatatactt gctcgaactg gtatatttcc aggtgtttta tttatagtgc
    30061 ttcttatgaa tctgtttctt ggaaaatata gaatagaatc aaaaacactg ttggctatgt
    30121 tagcctcatt tatgatttat attacaatgg agacttcatc tatgagcata ttgctgctaa
    30181 ttattgttct ttgtgtatat tggccacgtg gagaggagaa gttgcatgag caagttactt
    30241 aataccatct attatcgact atttagatta tataaaaaaa tttatctaca agtttttagt
    30301 aaaaaaacgg ttgacatctt gggtgaaaag gctaatttag aaaatgaact aattgtttcg
    30361 tttacaacaa ttccaagtcg tcttaattat ttaccaagta tgattaaaag tattttcaat
    30421 cagacaatta tccctaaccg ttttattatg tatgtttata aagatgaatt tgaaggcatt
    30481 aatttggaga gtattctaga acttgaaatc aaaaatggtt tggaaattgt ctatgtggat
    30541 gagaatcttc gttcacacaa aaaatatttt tatgctatga aggataatcc gaacagtata
    30601 gttgttctag ttgatgacga tatcatttat cctcgaaata ctataaagaa actgattgca
    30661 tcctatagaa tttatccaca gtgtgtttca gcaatgcgat gtcatcgaat taagttgttt
    30721 tctgatggaa gtttatatcc atataatcaa tgggaatatg aaatatcagg agctactata
    30781 ccatcgtatt ttaatttttt tactagcgga ggtgggacat tatttcctcc atgtactcgc
    30841 aatgaggatc tttttaataa aaaaaatatc agggaactca gttttctagc tgatgatgta
    30901 tggttgaatt ttttggtagt caaaaatgga attaaaacag taaaagcaac acgatataaa
    30961 gggacaccat taactataga tgacaatcct gaggagagtt tggtatattt gaataccgta
    31021 tatgataaca acaatgataa atgtattaga aatatggttg aatattatca aattaatttt
    31081 acagaggata aataatgaat gttgaaaaaa atttgaaacg tggaattttc tatactgcaa
    31141 tagggaagta ttcgaatgta gttattcaat tacttgtaac agcaattctt agccggattc
    31201 tctcacctgt agaatatggt atcgtagcag tagtaaatgt atttctttta ttttttcaaa
    31261 tgttagcaga ttcaggaata ggacctgcta ttgttcaaaa taaagaactg aataagtcag
    31321 atttaatcag cattttctca ttaacgattt atagtggaat cgtactttct tgtatttttg
    31381 ctttactagg atatcctatg ggggtgttat acggcgaaac tatttatgtt agtttatttc
    31441 cgcttttagg tctttgtgtt ttattttata ccattacaat tgtaccgcaa gctattctaa
    31501 tgaaaacgat gaactttaaa atagttaatt ttctaactat tttttctaac attgctagtg
    31561 gcttggtggg cgttattcta gcggtatcac attttggtgt ctattctcta attttttcta
    31621 atattgtaaa agcaatggtt ttatttatcg ctttatattc taaagcaaag ataaatttct
    31681 attggaaagt ttcaaaaagt tctattggta aaatttttga gttttcaaaa ttccaatttt
    31741 tgtttaattt ttggaattat tttgctagaa atttagataa tttattaatt ggacgattga
    31801 ttagcccgtc agatcttggt tattatgata aggcttatca attatctttg taccctaatc
    31861 aaattttatc acaggttgtg acaccagcat tgcatcctat tatgtccaat tttcaagata
    31921 atatcagtaa gataggcgaa gtttatcttc agatttctag aatattcgta atagttggca
    31981 tacctatttc ggcttattta tactttaatg ctcaatatgt tgttacattt atgtttggag
    32041 ataattggtc ccaaagcgtt ccggtgtttc aaatattagc agcaacaatt tggttacaaa
    32101 tggctaatag ccctactggt gcattttacc aagcaactaa tcagacaaag ttattgttta
    32161 gaattggctt attgacatct tttattaata ttttagctat tgttattggt gtaatgttgc
    32221 aaagcatcca atgtgttgcg tacatgcttt tgatttcttt cagtcttagt ttagtaatca
    32281 atactcttta cttaacaaaa aaagtattaa atatttctgc tcaaaaatat ataaaaccga
    32341 tattaattaa tttga
//
LOCUS       DAVLAQ010000024        28958 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000024 DAVLAQ010000000
VERSION     DAVLAQ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.024"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..1823)
                     /locus_tag="VXB71_001085"
     CDS             complement(<1..1823)
                     /locus_tag="VXB71_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0451212.1"
                     /translation="MIYLTEGNTPLNEAYNDEIVHLGNNTYQLTFRFPTSDTKWELLK
                     EETFLTADDLHGEQDFYIFEVEKQQGYIQVYANQVISLLNNYIVSSIEVDRVSGTRVL
                     SAFAGSITRANPFSFFSDIDDRHTLNIKDKNAMEVLAKGKHSILGQWGGDMVRNGYNL
                     RLLKNGGSENESLFMYKKNLSSYQHKTSTKSLKTRITFKTTVKGEGENAVDHDYMVVI
                     DSPLLGNYSQIYEDVVEVNDQDVTDEASLIEYGKQYFRTSMCDMLEDNLEISVVGQSD
                     VAVQMFDVVSFYHEWYGLDVRKKITKYTYSPMAKLLKSIGFGTFQSSLANAIGGIVND
                     AVLNESRNLHQIFEERLKKEIANADRAFDAEFSKREKTITDAIELAKAKAEEVKQELS
                     DTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQTT
                     SAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASSSLAQEAK
                     RIELDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAETEIAKQVEALS
                     RTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELT"
     gene            complement(1820..2518)
                     /locus_tag="VXB71_001086"
     CDS             complement(1820..2518)
                     /locus_tag="VXB71_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0451213.1"
                     /translation="MFYMIINGFNTSTIPHCVVTDFGQVEAAKPRVVEDANLYGANGS
                     YRVLDGGYESYERTFSFYIPKLLDVSTIVEKFQPKDNVLEFSYQLGSVFYADFIGATY
                     SPHGMHAWKLEIKLNMQPFRYQKNVAPLIFTASGNINNPGSVYSEPVIEIEGDGDISL
                     TIGRTTMHLTVRRKVTIDCRHKKQNIYNADGAVQNTLRKRGGFFELAVGNNSLVFTGS
                     VRKVTVRPNWRYIL"
     gene            complement(2518..6693)
                     /locus_tag="VXB71_001087"
     CDS             complement(2518..6693)
                     /locus_tag="VXB71_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEV0451214.1"
                     /translation="MASGTPLGAMYIELGLDVSNFNPTLTGAKNAVKYFQNTVRSLDS
                     TLKGNEKNASLLQAKYKTLGQAIDSQRKVLDEMKKSFDKLEPGTAKFDKAAADIQREN
                     AKLAAMEGQLRGVEKALQDVGRENSWSGKMDALSEKFAKGGKKLRAMGDAMKPVSAAL
                     LAGFTLSTKKAIDFESQMNTTKSLLADTIPTADELNSTTQKLGESSKNWAKQYGISTA
                     SINEGMQEIIKKGFDANQTIEAMPAILDAAKASGEDFNTVMNATTNILQQFGLSTQDT
                     ERVTNSLTFVANKTAAGFADMGAAMEYVGPVAKNVGMDLEETAATVGLLSNNGIAGEK
                     AGTALRGALTRLLKPSKQNANAMAKLGFSAEEFRSGAIKLPDILDRIKKNTEGMTDAQ
                     KSALIATAFGTEAQTAMNILVDQGGDALRNLANETKGATTYTKDLANELSKSSKNGVE
                     RFKSSLEVLQINIGQKLLPLLTPVIEKVNQFIDWLSKAPPAVQSLAVGIGGFLALGYP
                     LLNFLGNGATALSILIKHAGKLGGLLKGGIGLAKLTERAGKLKGLLQGGIGLAKVGSE
                     ATVLAEGAGVAASSSGLLSGAIGALTNPIGLLVGGVALLAGGLVYLGHKKDEARIKAE
                     EFGSQLSDTARKELRDFQSKVDETSKAVANFGTHAGDAEKVSGAFKKLYDEIAAGAEK
                     SNQRMQELTGKWGLSEEDLAKAREKNAQMVSNAESMMNKINDIYQRHNGDASKFSQEE
                     KEIILNNQREMIKTRISMMNLSAEQQKAALQALNGEIGSLNETQLKHTRDVLKKSLDE
                     EKQLYETSKSELKELLEGKVIDQETYNKKLQTLETNHQQTMEALGTKYYQVMQNLDAK
                     VKARTGQSWNYWEEAKKVLEEYGLSYEVIGQKAAEASQKMGESHSILAKYTSEMSKET
                     KEANDAWSLLVGNINENGNFEIKSNVKEVIGEATKSAEGWEQLQFIVKSANINSNARV
                     MIAEALVESGKWSTMTLEEKQLIVQNQAGLQAIFDSENHLRIWNSMPAEVKQLLLENT
                     DVMNKAEEASKALYNYDALTPKQKELLATDENFRKAVARSTDTLTTWNATTPFTKDLK
                     LDPTNVLNNGQLSIDKIMVWNLSNPETKSLNATDNTSEAVDSAKASVNSPKQEKPIDL
                     LAKDQTAGVRNETSAAINAIKQNNPVDILAKNSTSSTVSEVKSGVNSIQDKTVTISAR
                     DNASGVLAGIRSWIIRVTGDFFTNVFASRHAHGTNYHPGGLAMVNDQRNSTYKELVTL
                     PDGRSFIPEGRDVLLPLPKGAKVLRADKTKRLMREMGVPKYAAGVGIPSDAKFLREME
                     EAQAKIVVQAKGETNSKDSDKVVSEIAILRASMEKILTAILEKPSDTYLDADKISMSV
                     YQRQGAIYAREGM"
     gene            complement(6750..6980)
                     /locus_tag="VXB71_001088"
     CDS             complement(6750..6980)
                     /locus_tag="VXB71_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451215.1"
                     /translation="MSRKEKARRRYWFWFTIFILYLAFGLYCICTNFGDTLGMLLLSP
                     FIFASLPLYAYLFLGLFIWAFMSLAMDDFYKE"
     gene            complement(7229..7522)
                     /locus_tag="VXB71_001089"
     CDS             complement(7229..7522)
                     /locus_tag="VXB71_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451216.1"
                     /translation="MAKVQFTIKNDKGEDVLKKSKEITTRDYRDYLVMNDSLTSDLSE
                     VEKLDKQLGFIASLFDDVTVEQLLEYTDFAKVISIFTDIYAHLVGDVDPKEKS"
     gene            complement(7571..8167)
                     /locus_tag="VXB71_001090"
     CDS             complement(7571..8167)
                     /locus_tag="VXB71_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0451217.1"
                     /translation="MTVKGTALIGLKSVTIRVHDGQTPTVGQNLFTLEGKDNEGATQT
                     ARVTGLSSDPVKTYGSNVAYHVSNRGVGDVKVEMGLLDVPLALYTNALGYGDDDGIYY
                     FGADTVAKNVSILIESNTADGEPVYYGFYKGQLSMDAIDFETIKDKANELATTNVNFA
                     ATASSDTATKGRYGAIVYGSDAEKLKKLKGQLNMAAAG"
     gene            complement(8184..8564)
                     /locus_tag="VXB71_001091"
     CDS             complement(8184..8564)
                     /locus_tag="VXB71_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451218.1"
                     /translation="MIKDKLTELYDALEEDESLSGISIKSFERPESLGDDETSIVIIP
                     VGPPMQTAHGSNTSLAKTFLYQINVESTNRVECKELQGRIEKIMEEQGFYQTEGGLEQ
                     WIPDIKRYVDVRTYRGMSALYEKY"
     gene            complement(8564..8962)
                     /locus_tag="VXB71_001092"
     CDS             complement(8564..8962)
                     /locus_tag="VXB71_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451219.1"
                     /translation="MSSGANLKGFDDILRNIEARLGEPVVRRNVNRALKETVEEFEPT
                     FKRAMAVYADTGKTVGAVVHGNVTGTSSGVPMVKLGFKSPRWTLIHLNEFGYAKNGHP
                     RGFGVMRRFFEASKPVFKSKVGMKLKQEFL"
     gene            complement(8955..9344)
                     /locus_tag="VXB71_001093"
     CDS             complement(8955..9344)
                     /locus_tag="VXB71_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0451220.1"
                     /translation="MKRSEGPSYRYKKPESQNGDLRTPLTFYTSKIKKGVDGRDVSYE
                     KAFYTMGQTYSPSMKDVEIATGKAMKAKMTLKIRDPLTDYQPENRHFVEVGDIRLVGK
                     KWQIIDVRPDYDNRDFLIVLIGGGRDV"
     gene            complement(9331..9519)
                     /locus_tag="VXB71_001094"
     CDS             complement(9331..9519)
                     /locus_tag="VXB71_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451221.1"
                     /translation="MIKVLKEFYDLKEGVLRQVGGRFEATEERFAELKEHLPGYVELE
                     KSSRSRSSKEVVSVNEEE"
     gene            complement(9512..9802)
                     /locus_tag="VXB71_001095"
     CDS             complement(9512..9802)
                     /locus_tag="VXB71_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEV0451222.1"
                     /translation="MEIEAKLHSLLDPFKERMRIFHSGEDANLSRMLESSQMVITRLV
                     GSGNIHDHQIRELILERARYVYNDQVEFFYENFKADILALSLDKIEMEDSDD"
     gene            complement(9816..10931)
                     /locus_tag="VXB71_001096"
     CDS             complement(9816..10931)
                     /locus_tag="VXB71_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEV0451223.1"
                     /translation="MMKLGNEFTTARQNFMNAVETGAPMEEQNKLYNEMIEALTDKLQ
                     DDAREAARKEIATMNPYDAQLTAEAREFFNNIEKLPPKGIEKLFPQETIDRIFEDMVA
                     ARPLLQHIGLRNAGIRLKFLKSSRTGQAVWGKINAEIQGQLKQEFAEEEAIQSKLTAF
                     VVIPKDSEKFGPAWLQSYVSIQITEAFAAALEAGYLNGDGDKQPIGLSRTLTGTVESE
                     KVTYAEKQAQKKPLTFADSATVVKELTEVYKYHSTKADNTTPVAVEGNLVMVVNPVDA
                     WDVKKQYTSLNAQGVYVTAMPYNLILVESVAQTSGKVTTFVKGRYDAFVGGGIEFGRF
                     TETYALEDLNLYTAKQFAYGKAHDEKTAAVWTLNIGK"
     gene            complement(10950..11672)
                     /locus_tag="VXB71_001097"
     CDS             complement(10950..11672)
                     /locus_tag="VXB71_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEV0451224.1"
                     /translation="MTIIQIKGAIVSNDDRWFYDWIDMDATAPKDIVLPTTGEDVEVH
                     INSGGGDVYAGSEIYTALRAYQGHVTVKIVGIAASAASVIAMAGDQVEISPTAQIMIH
                     NVSAGVRGDHKALLHEAGVLEGFNKSIAYAYIDKTGKALDDLLDLMEGETWFDARSAV
                     NHGFADKVMFESQEAPVLVASQTPVIPRDFIEKIRSAMTPDVELLADLVRDRLNNSLL
                     IPEDKKKEDKTAEPVGLGRFPF"
     gene            complement(11653..12801)
                     /locus_tag="VXB71_001098"
     CDS             complement(11653..12801)
                     /locus_tag="VXB71_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0451225.1"
                     /translation="MGFLNLFKRDAPDVGFDFEELERMLGRLQLKSLAIDKSAEFVAR
                     IFAKSEFRYMVENHHVASDWDYILNVRPNKNESASEFWQKVIYRLLTKNEVLIVLSDD
                     KQLLVADAFTRRRYALYDDTFEMVSVGDYIFQRKFAMSDVIFLQYNNNRLQEYVSDLF
                     SDYEKLHTRLVEALARNNQIRGVLATKANGTFDDDKRKKLQRYADNLFKSFTSKTVAI
                     VPTMDGVEYSELTNTVGTTNLSVEELKKLRRQFDDEVADILGLPTALMHGDMADLSNS
                     QKMFNSYCYESLVKKVGDALNHAMVSSAGYANQKKFVIFGEGGLDKFALAENIDKLIS
                     SGAMTRNEVRLELGLEAVPGGDSFLITKNYQGENEIEKGGNEDDNHSD"
     gene            complement(12858..14498)
                     /locus_tag="VXB71_001099"
     CDS             complement(12858..14498)
                     /locus_tag="VXB71_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV0451226.1"
                     /translation="MISHPLVDDYIKMAESGEIVVNKERKLLFKIIKEKIYPRDDLYF
                     DNDLIDKFIRFAEKNFFPLAKYQLFLTPFIFLFRKEDGEPHFDEYLYTLARGGGKNGF
                     MSARSSFFISPIYPIRDYDVTITANSEKQGKVSFEEVYETIQRRGLEDHFYLTKMSIT
                     GRANNSVFSFRTNNPKTMDSARDGCLEFDEIHQFEDDKAVKVQRSGLGKIAHARTFYN
                     GTNGYVREGFYDKLIEKSMQILNGEVDDFRLFPFICKLDSADEVDDMKKWPKANPMLD
                     ESTPYAKRLLARTKADYDDLELEPSGRQEFMTKRMNLPEADLEKDVTSREKLVACLRS
                     PGIDLLGKSCVAGFDYASIRDFASVGLLFKNGDEFIWKQHSFARKVFLKAFKLKAPIQ
                     EWADKGLFTIVDGPSIDPRLLVAKLEEWSKFYQIELVCADGFRMDLLKPLLEEAGFEY
                     EFLRNPGAIQSKVAPIIEDGFANERFVFENDNSMIWYTDNTYIKEDKDGNKRFLKKEP
                     VRRKTDGFHALIAALYKRELVHESNVGEFLDMLDSWDF"
     gene            complement(14495..14833)
                     /locus_tag="VXB71_001100"
     CDS             complement(14495..14833)
                     /locus_tag="VXB71_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451227.1"
                     /translation="MEEYSEKNIKELENQLLSKIGYFSPRKKDAIQYEKVNRYLYLVR
                     LLYELKAKLHEDGLVITVHNGQQRFQKANSLIKEINTTSNQLLAIERSFDFEVENSPV
                     EKPTSGSDLL"
     gene            complement(14952..15248)
                     /locus_tag="VXB71_001101"
     CDS             complement(14952..15248)
                     /locus_tag="VXB71_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0451228.1"
                     /translation="MIDVSTREERNQFYNSSEWRTIRRQALKRDHYECVWCRDEGKVT
                     TTNLEVDHIKELELYPEFALDIDNLRTLCKACHNKRHDRFDKNDRNFRKDEWWG"
     gene            complement(15245..15451)
                     /locus_tag="VXB71_001102"
     CDS             complement(15245..15451)
                     /locus_tag="VXB71_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451229.1"
                     /translation="MKGIIKRLFNKRTTKQKPLGKIVVGVEIENRSELKELTQQCCEA
                     IEHLNNCIDKLNKFELKVSTSIIK"
     gene            complement(15617..16183)
                     /locus_tag="VXB71_001103"
     CDS             complement(15617..16183)
                     /locus_tag="VXB71_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0451230.1"
                     /translation="MVVVEPIRNRDDVQLMIEWLTLHSAVKESDRQRNLMLFLSGVNL
                     GFRIGDIVKLKVKHVKGWHVQIVDEKTDKPTKRKMPKKFKNAMRQYIKDKKDEDFLFP
                     SRNGKHQHIKPNTAYKIIKRAAEEVGLENIATHSMRKTFGLFMYEQTKDVALIMDLLN
                     HSSQSISLRYIGKNQDSQDRAMTKFQGF"
     gene            complement(16270..16695)
                     /locus_tag="VXB71_001104"
     CDS             complement(16270..16695)
                     /locus_tag="VXB71_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000963208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0451231.1"
                     /translation="MAIDIKKRLKALPYIDIKAKSKHQEIISLKSGILRGQQFDSMPK
                     SKSNKNQTEELNVLIIDKSEQLYKEIKQMYHERDELVQAIESLDDPVENIVMRLLYID
                     GLSWKEVQIKLNCSPATIQRAKHKALLKLSKMYDKNDSK"
     gene            complement(16699..17097)
                     /locus_tag="VXB71_001105"
     CDS             complement(16699..17097)
                     /locus_tag="VXB71_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451232.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNIYENPVRR"
     gene            complement(17109..17387)
                     /locus_tag="VXB71_001106"
     CDS             complement(17109..17387)
                     /locus_tag="VXB71_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451233.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            complement(17489..18571)
                     /locus_tag="VXB71_001107"
     CDS             complement(17489..18571)
                     /locus_tag="VXB71_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0451234.1"
                     /translation="MKFLDLFAGIGGFRLGMESAGHKCIGFCEIDKFARESYKAIHNT
                     KGEIELHDITAVSDESIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRRERTRRFFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIIQRG
                     HGYNKGGEHDIAPTLTSNSYHENNHLSDGFRIRKLTPRECWRLQGFPDWAFDKAQEVN
                     SNSQLYKQAGNSVTVNVIAAIAKELS"
     gene            complement(18602..18889)
                     /locus_tag="VXB71_001108"
     CDS             complement(18602..18889)
                     /locus_tag="VXB71_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451235.1"
                     /translation="MTQTLEEGMKNKSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEERV"
     gene            complement(18889..19476)
                     /locus_tag="VXB71_001109"
     CDS             complement(18889..19476)
                     /locus_tag="VXB71_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0451236.1"
                     /translation="MNKDLIETPRFNFFIGDEVLLKGKIVGFDVDENKCVENVVRLEY
                     GQTLNVPNNNIYITDDIVDKSKIKVVVPQFVADWYEENKDSFEFNVWDWIAFRDEAKK
                     SENREFNNWINNSRENPIQTLVNMHQFGYEVEEEKRYTVVTKATKQPLYYNAMDKKLF
                     FSMGGLATKFTRKQLEEVGVGWVFDCPGIEIEEVE"
     gene            complement(19469..19969)
                     /locus_tag="VXB71_001110"
     CDS             complement(19469..19969)
                     /locus_tag="VXB71_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0451237.1"
                     /translation="MNKQELIKKLEERRTMTRNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQFVADFIAEQKKLGHTLSYSIDASMSDIVAEWYWDNSELFALAWLNGYEVEKEKRY
                     FVKIKGNIKENMLVYGEFLKRYFFTKGFSLDDVIYSHTRKQLEDANFGWVFDCEGIDI
                     EEVENE"
     gene            complement(19971..20288)
                     /locus_tag="VXB71_001111"
     CDS             complement(19971..20288)
                     /locus_tag="VXB71_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451238.1"
                     /translation="MMEELKQKVNAVYNWTVEDGKPQPPKQDLPQVVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKDWLPKSREFDDWIGYSPSMAQVVIAVYLIY
                     GGN"
     gene            complement(20260..20469)
                     /locus_tag="VXB71_001112"
     CDS             complement(20260..20469)
                     /locus_tag="VXB71_001112"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451239.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKLEELEDDGRVKAKS"
     gene            complement(20456..20623)
                     /locus_tag="VXB71_001113"
     CDS             complement(20456..20623)
                     /locus_tag="VXB71_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451240.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGSPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            complement(20750..20977)
                     /locus_tag="VXB71_001114"
     CDS             complement(20750..20977)
                     /locus_tag="VXB71_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451241.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            complement(20977..21171)
                     /locus_tag="VXB71_001115"
     CDS             complement(20977..21171)
                     /locus_tag="VXB71_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451242.1"
                     /translation="MFILKHGTREDKPFLMSAVIGVTGLDISCSEEKKAMRFVSRGAA
                     VQVGKALRGSFGNFYPVEVE"
     gene            complement(21186..21956)
                     /locus_tag="VXB71_001116"
     CDS             complement(21186..21956)
                     /locus_tag="VXB71_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0451243.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQARVNELADAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LVFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(21950..22108)
                     /locus_tag="VXB71_001117"
     CDS             complement(21950..22108)
                     /locus_tag="VXB71_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451244.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(22096..22896)
                     /locus_tag="VXB71_001118"
     CDS             complement(22096..22896)
                     /locus_tag="VXB71_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0451245.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNRLDKDK
                     NKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAINS
                     GKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            complement(22889..23185)
                     /locus_tag="VXB71_001119"
     CDS             complement(22889..23185)
                     /locus_tag="VXB71_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451246.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRDVELKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(23201..23521)
                     /locus_tag="VXB71_001120"
     CDS             complement(23201..23521)
                     /locus_tag="VXB71_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451247.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     AYMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPELLALPEPKQSG
                     IRFL"
     gene            complement(23607..23864)
                     /locus_tag="VXB71_001121"
     CDS             complement(23607..23864)
                     /locus_tag="VXB71_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0451248.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(23877..24590)
                     /locus_tag="VXB71_001122"
     CDS             complement(23877..24590)
                     /locus_tag="VXB71_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEV0451249.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQVTMLEDIDYLKSEQPIHPSYAQSLLKKRKA
                     RVVACLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMELNSFDEG"
     gene            complement(24733..24936)
                     /locus_tag="VXB71_001123"
     CDS             complement(24733..24936)
                     /locus_tag="VXB71_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451250.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVASSVISELLKYG
                     KGSESVKEKVADVLGIENPWRNH"
     gene            complement(24948..25094)
                     /locus_tag="VXB71_001124"
     CDS             complement(24948..25094)
                     /locus_tag="VXB71_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451251.1"
                     /translation="MEDKIIELADYFISENTTYREAKIACEKLFKQASHEIELRALES
                     ETKK"
     gene            25213..25434
                     /locus_tag="VXB71_001125"
     CDS             25213..25434
                     /locus_tag="VXB71_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451252.1"
                     /translation="MSKLTKEDVLQVSQEIINDAIPVIQDMLDEVFKEYPIDMEIRKA
                     ILNSVLVAHKLSTETTVSLLTELVNAQEN"
     gene            25812..26174
                     /locus_tag="VXB71_001126"
     CDS             25812..26174
                     /locus_tag="VXB71_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451253.1"
                     /translation="MFFTFEKIKELADKQGISLNKLEEKLGFSRNTIYNMKKSTPNVE
                     RVSMIADYFNVSTDYLLGRTDNPTIAGSHDYKWEGKTLNVEEMASNVMMFGGRELTDE
                     KKKIIQSIIEGYLKEAGD"
     gene            26187..26570
                     /locus_tag="VXB71_001127"
     CDS             26187..26570
                     /locus_tag="VXB71_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0451254.1"
                     /translation="MTEKEIISHFQIRIIDFDGDLMPDELGFYEKETNTAFLSNKLSK
                     KERVKVLLHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDAIESLDDPTEFDYLK
                     FMSYYNLKTMTNEVMVKEEYFALME"
     gene            26583..27506
                     /locus_tag="VXB71_001128"
     CDS             26583..27506
                     /locus_tag="VXB71_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HEV0451255.1"
                     /translation="MSYSYVALDVETANDFRGSVCSIGLVKFKDGNIVDSFYTLINPE
                     EEFDDFNIFIHGITPEDVLDSPTFPEVRKAIVDFIGSDIVVAHFAQFDMGALKDVYQK
                     YELDFDNIEYICSYRLAKVALPGQLNYKLKRLAKNLNIELDHHNALSDARASGLILEY
                     LLSTNSFSDLNAFLKEYSYNKTGLLGQYGFKRKKSYQYKENLIYQPTEEEKAAMNPDH
                     YFYGLYFCFTGKLERMTRKEANKATALVGGIPEKGVTKHTNILVVGEQDWRVVGTDGL
                     SSKMKKAQTLLEKGQDIEIMTENDFIRLLEE"
     gene            27685..28833
                     /locus_tag="VXB71_001129"
     CDS             27685..28833
                     /locus_tag="VXB71_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0451256.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
BASE COUNT         8261 a         6856 c         4774 g         9067 t
ORIGIN      
        1 tgcgtgagtt ctgacttgct ggctttacca ttggccaagt tggtcagttc tgacagtcta
       61 cgagtcgtcg tctcctcata cgtcgcttgc gctgacttca cgccagccag ttcattttta
      121 gtccggctaa gtgcttcaac ttgcttggca atctcagttt cagcctgtgc ttgcttcggt
      181 cgaatatcat tcgcgatagt ccgtttcaga gcgtccaagt cacccgacag agccgtttgt
      241 gcgctcgtag tctgcgactt aaacgcttca agtctagcaa cagaatccag ctcaatccgc
      301 ttagcttcct gagcaagaga actacttgcg ccatccagtt catttttagt ccggctaagt
      361 gcttcaactt gcttggcaat ctcagcttca gcctgtgctt gcttcggtcg aatatcattc
      421 gcgatagtcc gtttcagagc gtccaagtca cccgacagag ccgtttgtgc gctcgtagtc
      481 tgcgacttaa acgcttcaag tctagcaaca gaatccagcc caatccgctt ggattcctga
      541 gcaagagaac tacttgcgcc agcatttcgc aaagcttcct cagccttgcg cttagcttct
      601 ttcaatggcc cgttgtcaaa gctattaaag cgctgattga tagtgtcaga cagttcttgc
      661 ttgacttctt ccgctttggc cttggcaagt tcgatggcat ccgtgatggt tttctcacgc
      721 ttggaaaatt cagcgtcaaa ggcacggtca gcgttggcga tttccttttt caaacgttct
      781 tcaaaaatct gatgcagatt tcggctttca ttcaaaacgg catcatttac aatcccaccg
      841 atcgcatttg caagactgga ctggaaggtt ccaaaaccta ttgattttag gagttttgcc
      901 attggcgaat aggtatattt ggtgattttc ttacgaacat caagaccgta ccactcatgg
      961 tagaagctga ccacatcaaa catctgcacc gcaacatcac tctgaccgac aaccgagatt
     1021 tcaaggttat cttctagcat gtcgcacata cttgtccgaa aatactgctt accgtattca
     1081 atcaagctag cctcatctgt cacgtcttgg tcattgactt ccaccacatc ttcgtagatt
     1141 tggctgtagt tcccaagtaa ggggctgtca atcaccacca tataatcatg gtcaaccgca
     1201 ttttctccct cgcccttaac agtcgtttta aaggttatcc gagtttttaa agacttcgtt
     1261 gaggtcttat gctggtagct ggacaagttt ttcttgtaca taaaaagcga ttcattttca
     1321 gaaccgccat tcttcaacaa gcgtaaattg tagccgtttc gcaccatatc tccgccccac
     1381 tgaccaagga tagaatgctt gcctttggcc aagacctcca tggcattctt atccttgata
     1441 ttgagcgtat gcctatcatc aatatcagag aagaaagaaa aaggattggc tctggtaata
     1501 ctaccagcaa aagcactcaa cacccttgtc ccactgacac ggtcaacctc gatagagcta
     1561 acgatgtaat tatttaacaa actgataacc tgattggcat agacttgaat atatccttgt
     1621 tgcttttcaa cctcaaaaat ataaaaatcc tgctcaccat gcaggtcatc tgcagtcaga
     1681 aaagtttcct ctttcagtaa ttcccacttg gtatccgatg taggaaaacg aaaggtcagt
     1741 tgataggtat tgttccccaa atggacaatt tcatcattgt aggcctcatt taaaggtgta
     1801 ttgccttcag taagataaat cataagatat acctccaatt cggccgaacc gtgaccttgc
     1861 gaaccgaacc agtaaagacc agactgttat taccaactgc caactcaaag aagcctccac
     1921 gtttacgtaa agtattttga accgcgccat ctgcattata gatattctgt ttcttatgcc
     1981 tacaatcaat ggtcactttt cgtctaacgg tcaagtgcat agttgtcctt ccgatagtca
     2041 aagaaatatc accgtctccc tcaatctcaa tcacaggctc gctatagaca gagcctggat
     2101 tgttgatatt tccacttgcg gtaaagataa gaggagcaac atttttctga taacggaacg
     2161 gttgcatgtt caacttgatt tctagtttcc aggcatgcat cccatgaggg ctataggttg
     2221 caccaataaa atccgcataa aatacagacc ccaactggta gctaaactct agcacattgt
     2281 ccttaggctg aaatttctcc acgatagtag aaacatccag taacttagga atatagaacg
     2341 aaaaagtccg ttcataactc tcatagccac catccagcac tcgataactt ccgttggctc
     2401 cgtagaggtt agcatcttca accaccctag gtttagctgc ctccacctga ccaaaatccg
     2461 tcaccacgca gtgagggata gttgatgtat taaacccatt gataatcata taaaacatta
     2521 cattccctcc ctggcgtaaa ttgcaccttg acgttggtag acgctcattg aaattttatc
     2581 agcgtctagg taagtatctg acggcttttc aaggatagca gtaaggattt tctccatact
     2641 tgctctcaga atcgctatct cagacacgac tttatcgctg tctttgctat ttgtctctcc
     2701 tttggcttga accactattt tagcttgtgc ttcttccatc tcacgaagga atttagcatc
     2761 actcggaatg ccaactcctg cagcatattt aggaacaccc atctcacgca tcaagcgttt
     2821 ggtcttatcc gctcgcaaaa ctttagcccc tttaggaaga ggaagaagaa catccctccc
     2881 ctcaggaatg aagctcctac catctggaag agtaactaat tccttgtagg tactattgcg
     2941 ttggtcattg accatagcaa gaccacctgg atggtagttg gtaccatgag catgccgact
     3001 agcaaaaaca ttcgtaaaga aatcaccagt taccctaata atccaagacc taatgcctgc
     3061 aagcacacca gaagcattat ctcgagcgct gattgtaacc gttttgtctt gaatactatt
     3121 aacgccactt ttgacctcgc taacagtact ggaagtgcta tttttagcaa ggatatctac
     3181 tggattattt tgcttaatcg cattaatagc cgcactcgtc tcatttctaa cgcctgcagt
     3241 ctgatctttc gcaagtaaat caattggttt ttcttgtttc ggagagttta cgctggcttt
     3301 tgcactatca actgcttcac tagtattgtc agtagcattt aatgatttag tctctggatt
     3361 agatagattc caaaccatga ttttatctat tgacaattgc ccgttattca aaacatttgt
     3421 aggatctagt ttcaaatctt ttgtaaacgg tgtggttgca ttccaagtcg ttagcgtgtc
     3481 agtcgaacgc gcaacagcct ttctgaaatt ctcatccgta gccagcaact ctttctgttt
     3541 aggagtcaag gcatcgtagt tatagagagc tttggaagct tcctcagcct tattcatcac
     3601 atctgtattt tccaaaagga gttgcttgac ttctgcaggc atactgttcc agattctaag
     3661 atggttttca ctatcaaaga tagcttgcag tcctgcttga ttttggacaa tcaactgttt
     3721 ttcttccagt gtcatagttg accacttacc agactcaacc aaagcctcag caatcatcac
     3781 acgagcgtta gagttgatat tcgcactttt aacaataaat tgcaattgct cccaaccctc
     3841 agcagattta gtcgcttccc caattacttc ttttacattg gatttaatct caaagttgcc
     3901 attctcatta atattaccaa caagtaaaga ccaagcatca ttcgcttctt ttgtctcttt
     3961 gctcatttcg ctagtgtatt tagcaagaat actgtgagat tctcccattt tttgagaagc
     4021 ttctgctgcc ttttgaccga ttacttcata agacaagcca tattcttcca gaaccttctt
     4081 cgcttcttcc cagtagttcc agctttgccc agtccgagct tttaccttag cgtcaaggtt
     4141 ttgcataacc tgataatatt tagtccctaa ggcttccata gtttgctggt ggtttgtttc
     4201 taaagtttga agtttcttgt tataggtttc ttggtcaata acctttcctt ccagcaactc
     4261 tttcagctca cttttagaag tctcataaag ttgtttttct tcgtccagag acttcttcaa
     4321 aacatctcgt gtatgtttca attgcgtctc gtttaaacta ccaatttctc cattcaaagc
     4381 ctgaagcgca gccttctgtt gctctgctga caagttcatc attgaaattc tagtttttat
     4441 catctctctt tgattattca agatgatttc tttttcttct tgagaaaact tactagcatc
     4501 tccattgtga cgttggtaaa tatcattgat tttgttcatc atgctttcag catttgaaac
     4561 catttgagca ttcttctctc tagcttttgc gaggtcttcc tcactgagac cccatttgcc
     4621 agtcagttcc tgcattctct ggttagactt ttcggcacca gcagcaatct catcataaag
     4681 ctttttaaaa gccccagaga ctttctcagc atctccagca tgtgtaccaa agttagcaac
     4741 tgctttgctg gtttcatcta ccttactttg gaagtctctt aattctttcc ttgcagtatc
     4801 actcaactga gaaccaaatt cctcagcctt aatacgcgcc tcgtctttct tatgccctag
     4861 atagaccaat cctccagcta gtaaagcaac accacccacc agcaaaccaa tcggatttgt
     4921 caaagcccca atagctccag acaagagacc agaactagat gcagcaacac cagctccttc
     4981 cgctaaaaca gtggcttcac ttcctacctt agcaagaccg ataccacctt gtaaaagtcc
     5041 ttttaattta ccagcacgct ctgtcaattt agcaagaccg ataccgccct ttaaaagtcc
     5101 tcctaattta ccagcatgtt ttatcaaaat actaagagcc gtcgcaccat tgcctagaaa
     5161 gttcaataaa ggatatccta gagccaaaaa accaccaata ccaaccgcca agctctgaac
     5221 ggctggagga gccttactta accagtcgat aaattggttc accttctcaa tcacaggagt
     5281 tagtaagggt aataatttct gaccaatgtt aatctgtaaa acttctaaac tagatttaaa
     5341 acgttccaca ccatttttag aagacttaga taattcattt gctaaatcct tagtataagt
     5401 tgtcgccccc ttggtttcgt tagcaagatt acgcaaagca tctccacctt ggtcaaccaa
     5461 gatattcatc gctgtctgag cttctgtacc aaaggctgta gcaatcaagg ccgatttctg
     5521 agcatctgtc attccttccg tattcttttt gatacgatcc aaaatatcag gtagcttaat
     5581 cgcaccacta cgaaattctt ctgcagaaaa accaagtttt gccattgcat ttgcattttg
     5641 cttagatggt ttcagcagcc ttgttaaagc tccacgaaga gccgtaccag ccttttcacc
     5701 agcaatacca ttattggaca aaagaccaac agtagctgca gtctcttcca agtccatacc
     5761 aacgttttta gcaacgggac caacatactc cattgcagcc cccatatcag cgaaaccagc
     5821 agccgtttta ttggcgacaa aggttaaact attggttact cgctctgtat cctgagtaga
     5881 tagcccaaat tgttgcaaga tattcgtagt ggcgttcata accgtattga aatcctcacc
     5941 agacgcctta gcagcgtcta ggatagcagg catggcttcg attgtttgat tggcatcaaa
     6001 acctttcttg ataatttctt gcatcccttc attgatagat gcagtagaaa tcccatactg
     6061 tttcgcccaa ttttttgaac tctcccccag cttttgtgtg gtactgttca gttcatccgc
     6121 tgttggaata gtatcagcta acagagattt agttgtattc atctgacttt caaagtcaat
     6181 cgccttctta gtcgaaagtg taaaaccagc taataaagca gcagatacag gcttcattgc
     6241 atcacccata gcccgcaatt tttttccacc tttagcaaat ttctcactca aggcgtccat
     6301 cttaccagac caactatttt cacgccctac atcttgcaaa gctttttcaa caccacgtag
     6361 ctgaccttcc attgctgcta acttggcatt ctcgcgctga atatcagcag cagccttatc
     6421 aaacttagct gtccccggtt caagcttgtc aaaacttttc ttcatctcat ccaaaacttt
     6481 acgttgtgaa tcaatggctt gtcccaaagt cttgtatttc gcttgaagta agctagcatt
     6541 tttttcattc ccttttaaag tactgtccaa agaacggaca gtattttgaa agtactttac
     6601 agcgtttttt gcaccagtta gagtaggatt gaaattcgac acgtccagcc ctagctcgat
     6661 atacattgct cctaacggcg taccgcttgc cattttgttc tccttcctaa ctcctcagag
     6721 caaagaaaaa agcccttacg gacttttcat cattctttat aaaaatcatc cattgccagg
     6781 ctcataaaag cccagataaa caaaccaaga aatagataag cgtagagcgg caaggaagca
     6841 aagataaagg gtgataataa aagcataccc aaggtatctc caaaatttgt acaaatacaa
     6901 tacaagccaa aagcaagata aaggataaag atggtaaacc aaaaccaata tcttctacgc
     6961 gccttttctt ttcgagacat atcttccacc tcccttatat agctctatta tattcctaag
     7021 tcttttattt gtaaagtcct gacttagaga ctctctaaaa aatctgccaa gtcaaccact
     7081 tcttcttgtt cactcgtttt catacttcca agaacgccca tcaagtcctc ccaactcgta
     7141 tccatcacgt cgcgaatact cattccataa ggaccctctg taacttgctt gataaagcca
     7201 taaaaacgtt ggatagcttg cccaggtgct agctcttttc ctttgggtct acatcaccta
     7261 ccagatgagc ataaatgtct gtaaaaatag aaatcacttt tgcaaaatct gtgtattcta
     7321 gtaattgttc tactgtcaca tcatcaaaca aactagcaat aaatcccaac tgcttatcaa
     7381 gcttctctac ctcagataaa tcacttgtca aggaatcgtt catgaccaaa tagtcacgat
     7441 aatcacgagt tgtgatttcc ttactctttt ttaggacatc ttctcccttg tcatttttga
     7501 ttgtaaattg aaccttagcc atatactttc ctttctaaaa acggtaaaaa agagagcttt
     7561 cgccctcctt ctaccctgca gcagccatgt ttagttgacc cttcaatttc ttcaactttt
     7621 cagcatccga accatagaca atagcaccat aacgaccctt agttgcggtg tctgaactag
     7681 ctgtcgcagc aaaattcaca ttagtagtag ctaactcatt agccttatcc ttgattgttt
     7741 caaaatcaat agcatccata gaaagctgac ctttataaaa accatagtaa accggttccc
     7801 catcagcagt attactttca atgagaatgg aaacattctt agcaacagtg tccgcaccga
     7861 agtaatagat accatcatca tcgccatacc ctaaagcatt cgtatataaa gctaatggga
     7921 catcaagcaa gcccatctct accttaacat ccccgactcc tcgattggag acgtgataag
     7981 caacattact accataagtc tttacagggt cactagataa tccagttact ctagcggtct
     8041 gtgtagcccc ttcattatct ttaccttcta gcgtaaagag gttctgtcca accgttggag
     8101 tctgtccatc atgcacacga atggtgactg atttaagtcc gataagtgca gttcctttta
     8161 ctgtcatttc tttttccttc tttctagtat ttctcatata gagcgctcat accacgataa
     8221 gtccgaacgt ctacatagcg cttaatatca ggaatccatt gttccaaacc accttcagtc
     8281 tgataaaatc cctgttcttc cattattttt tcaattcttc cttggagttc tttacactcc
     8341 actcgattag tagactctac attgatttga tagagaaaag tcttagccaa actagtatta
     8401 ctaccatgag ccgtctgcat tggaggccct acagggataa tgacaatact ggtctcgtca
     8461 tctcccaagc tctcaggacg ctcaaaagac ttgatactaa taccagataa agactcatcc
     8521 tcttccaaag catcgtagag ttcagttaat ttgtctttaa tcattacaaa aactcctgtt
     8581 ttaacttcat gccgacttta gacttaaaga ccggcttact cgcttcaaaa aagcggcgca
     8641 tgactccgaa accacgagga tgcccattct ttgcatagcc aaattcattt aagtgaataa
     8701 gagtccaacg aggactttta aaacctaatt taaccattgg aactccgctg gatgtaccag
     8761 tcacattccc atgaacgacc gcaccaaccg tcttcccagt gtcagcgtac accgccatag
     8821 cccgtttgaa agttggctca aactcctcaa ccgtctcctt caaggctctg ttgacatttc
     8881 tacgaactac cggctctcct agtcgagcct caatattcct caaaatatca tcaaatcctt
     8941 ttagattagc tccactagac atcacgacca cctccgataa ggacaatcaa aaaatcccga
     9001 ttatcataat caggacggac atcaatgatt tgccatttct taccaactag acggatatcc
     9061 cccacttcga caaaatgccg attttcaggc tgatagtctg tcagagggtc acgaatcttc
     9121 aaagtcatct tagctttcat cgcttttcca gtcgcaatct caacgtcttt catacttgga
     9181 gaataagttt gccccatcgt ataaaaagcc ttctcgtaac tcacatcacg accatcaacc
     9241 ccttttttta ttttagaggt atagaaagtc aggggagttc tcaggtctcc attttgagac
     9301 tcaggctttt tgtaacgata gcttggtccc tcactcctct tcatttacac tcactacttc
     9361 cttagagcta cgacttctgg acgacttttc caactcgaca tagccaggta aatgttcctt
     9421 tagctcagca aatcgttctt ctgtcgcttc aaaccttcct ccgacctgcc taaggactcc
     9481 ctccttgagg tcataaaact cttttaatac cttaatcatc actatcctcc atttctatct
     9541 tatctaacga taatgctaaa atatccgctt tgaaattttc gtaaaaaaat tcaacttggt
     9601 cattatagac atagcgagca cgttctaaga taagttccct tatttgatga tcgtgtatat
     9661 tcccacttcc taccaagcgg gtaataacca tttgagaact ttctaacatc cgtgagagat
     9721 tcgcatcttc tccgctatga aaaattctca tccgctcctt aaaaggatca aggagggaat
     9781 gaagtttagc ttcaatctcc atccttagtc accttttatt ttccaatatt cagtgtccac
     9841 acagcagcag tcttttcatc atgcgcttta ccataagcaa attgcttagc agtgtagaga
     9901 ttcaagtctt ctaaagcata ggtttcggta aatcgtccaa actcaatccc accacctaca
     9961 aaggcatcgt agcgaccttt gacaaacgtc gtcaccttac cagaagtttg agcaacagac
    10021 tcaaccaaga tgaggttata aggcatagct gttacatata caccctgagc attgagagac
    10081 gtatattgct tcttcacatc ccaggcatct acagggttca ctaccataac caaattacct
    10141 tctactgcaa caggagtggt attgtcagct tttgtagaat ggtatttata aacctccgtc
    10201 aactctttta ccacggtagc agagtctgcg aaagtcaatg gttttttctg agcttgtttc
    10261 tcagcataag ttactttttc actttctaca gtccctgtaa gagtacgaga cagcccaata
    10321 ggttgcttgt ccccatcacc attcaaataa ccagcttcaa gagcagcagc aaaggcctct
    10381 gtaatttgaa tagagacata agattgcaac caagccggac caaatttctc agagtcttta
    10441 gggattacaa caaaagcagt caatttagac tgaatcgctt cttcttcagc aaattcttgt
    10501 ttcaattgtc cttgaatttc agcattgatt ttaccccaaa ccgcttgacc tgtacgacta
    10561 gacttgagga atttcaaacg aataccagca ttacgcaagc cgatgtgttg aagaagtgga
    10621 cgggctgcca ccatatcctc aaaaatacgg tcaattgttt cctgagggaa caatttctca
    10681 attcctttgg gaggaagttt ctcaatgttg ttgaaaaatt cgcgagcttc agcagtcaac
    10741 tgtgcatcgt atggattcat agttgcgatt tctttacgag cagcttctct agcatcatct
    10801 tgcaacttat ctgtcaatgc ctcaatcatc tcgttataga gcttattttg ctcctccata
    10861 ggagcaccag tttctactgc attcataaag ttctgacgag cagttgtaaa ttcattacca
    10921 agtttcatca ttgtttttta tttcctttct taaaatggga aacgacccaa ccccacaggt
    10981 tcagccgtct tgtcttcttt tttcttatct tctgggataa gtaaactgtt attcaaccta
    11041 tcacgaacca agtccgccaa taactccaca tctggggtca tcgcagatcg gattttttcg
    11101 ataaaatcac gaggaatcac aggtgtctga ctagctacca agacaggagc ttcctgactt
    11161 tcaaacatga ccttatctgc gaagccatga ttaacagcag aacgagcatc aaaccacgtt
    11221 tcaccctcca ttagatccag taaatcatct aatgccttac cagtcttatc aatataggca
    11281 tatgcgatgg acttattaaa cccttctaac acaccagcct catgcaagag cgccttatgg
    11341 tcaccacgta caccagcaga tacattatgg atcatgattt gcgctgtagg actaatttcc
    11401 acctgatcac cagccatagc gataacactc gcagcactag cagcaatccc cacgattttc
    11461 accgtcacat gcccctgata agcacgcaat gctgtataga tttcactacc agcatacaca
    11521 tcaccaccac cagaattgat gtgcacctcc acatcttctc ccgtcgtcgg caatacaata
    11581 tccttaggag cagttgcatc catgtctatc caatcataaa accagcggtc atcattggat
    11641 acaatcgctc ccttaatctg aatgattgtc atcctcattt cctcctttct ctatttcgtt
    11701 ttcaccctga tagttcttag tgataaggaa agaatcccca ccaggaacag cctcaagacc
    11761 aagttccaat ctcacctcat ttcgagtcat agccccagat gagatgagtt tatctatgtt
    11821 ctcagccaga gcaaacttat ccagtccccc ctcaccaaaa atcacaaatt ttttctgatt
    11881 agcgtatcca gccgaactca ccatagcatg gtttagagcg tcacccactt ttttaaccag
    11941 cgattcataa caataactgt taaacatctt ctggctatta gacaaatcag ccatatctcc
    12001 atgcatcaaa gccgtcggca aacctaatat atccgcaacc tcgtcatcaa attgacgtct
    12061 cagtttcttc aactcttcaa ctgatagatt tgtagttcct accgtattgg tcaactccga
    12121 atactccaca ccatccattg tcggtacaat ggcaaccgtc ttagacgtaa aggacttaaa
    12181 aagattgtcc gcatatctct gcagtttttt tcgcttgtca tcgtcaaagg ttccattcgc
    12241 ttttgtagcc agaaccccac gaatttgatt atttctagct aaggcttcca ctagacgagt
    12301 atgcagtttt tcataatcag aaaacaagtc tgatacatat tcttgcaagc gattgttgtt
    12361 atactggaga aagatgacat cactcatagc aaacttcctc tgaaatatat aatccccgac
    12421 agacaccatc tcaaaggtgt catcatacag agcataacgc ctacgagtaa aagcatcagc
    12481 taccagtaac tgcttatcat cagacaagac aataagtact tcgtttttcg tcaataagcg
    12541 ataaatgacc ttctgccaaa actctgaggc cgactcattc ttattgggac gcacatttaa
    12601 aatataatcc cagtctgacg ccacatgatg attctccacc atataccgaa attccgactt
    12661 agcaaagata cgagccacaa actccgccga cttatcaatc gctaaactct tcaattgcaa
    12721 gcgtcccaac attcgttcca actcttcaaa gtcaaaacca acatcaggcg catcacgctt
    12781 aaataagttt aagaatccca tgcttcccct ccttcctctt atttttgccg accacccacc
    12841 caaaatttat tcttagatta aaagtcccag ctatcgagca tgtcaaggaa ttccccaacg
    12901 tttgactcat gtactagctc cctcttgtat agagcagcaa tcaaggcatg gaaaccatct
    12961 gtctttcttc tgaccggctc tttcttcaag aaacgcttat tgccatcctt atcctctttg
    13021 atataggtat tatccgtata ccaaatcata gagttatcgt tctcaaagac aaaccgctca
    13081 ttggcaaatc cgtcttcaat gattggcgca accttagatt gaatcgcccc aggattccgc
    13141 aagaactcat attcaaaacc agcctcttcc aaaagcggtt ttaacaagtc cattctgaaa
    13201 ccatcagcac atacaagttc aatctgataa aacttactcc attcttccag cttcgcaacc
    13261 aacagccgcg gatcaatgct aggaccgtcc acaatcgtaa acaaaccttt atctgcccat
    13321 tcctgaatag gggcttttag tttgaaagct ttcaaaaaca ctttacgagc aaatgaatgt
    13381 tgtttccaga taaactcatc cccgttctta aacaacaaac caacacttgc aaagtctcga
    13441 atactagcat agtcaaaccc tgcaacacaa gacttaccta acaagtcaat accaggtgaa
    13501 cgcaaacaag caactaactt ttcacgagag gtgacatctt tctcaaggtc agcttcagga
    13561 aggttcatcc gtttagtcat aaactcctga cgaccagatg gttccaactc aaggtcatca
    13621 tagtcagctt tagttcttgc aagtaacctc ttagcgtaag gagtgctttc atccaacatc
    13681 ggatttgcct ttggccactt cttcatatca tccacttcat ccgcactgtc taacttacag
    13741 atgaaaggaa agagcctgaa atcatcaacc tctccgttca agatttgcat agacttctct
    13801 atcagcttgt cataaaatcc ctcacgcaca tacccattcg taccgttgta gaaagtccga
    13861 gcatgagcaa tcttaccgag acctgaccgt tgaaccttca cggccttatc atcttcaaac
    13921 tggtgaatct catcaaactc aagacagcca tcacgagcgg agtccatggt cttcggatta
    13981 ttcgtccgaa aagaaaagac cgagttgttc gctcgacctg taatagacat tttagttaga
    14041 tagaaatggt cctcaaggcc acgcctttga atagtctcat agacctcctc aaatgaaacc
    14101 ttgccctgtt tctcagaatt ggcagtgata gtcacatcat aatctctgat agggtagata
    14161 ggactgataa agaacgagga tctggcagac ataaaaccat tcttaccacc cccacgagca
    14221 agtgtgtaca aatactcgtc gaagtgtggc tccccgtctt ccttccgaaa aagaaagata
    14281 aacggagtca agaaaagctg atacttggcc agagggaaaa aattcttttc cgcaaaacga
    14341 atgaacttat caatcaagtc attatcaaaa tacaaatcat cacgaggata gattttctcc
    14401 ttgatgattt taaacagcaa cttcctttcc ttgttgacga caatttctcc actctcggcc
    14461 attttgatgt agtcatcaac caagggatga gaaatcatag caggtcactt ccagacgtgg
    14521 gtttctcaac aggagaattt tcaacctcaa aatcaaacga tcgctcaata gccaaaagct
    14581 gattgcttgt tgtgttgatt tccttgatga gagaattcgc tttttggaat ctctgttgcc
    14641 cattgtgaac agtgatgacc aatccgtctt catgaagttt agctttcagc tcatatagca
    14701 atctgacaag ataaagataa cgattcactt tttcgtactg gatcgcatcc ttttttctcg
    14761 gactgaaata gccgattttg gaaagtagct gattttctaa ttcttttata tttttttccg
    14821 agtattcttc cattaccccc cacccccttt aattttttgt taaaaatttg gacagtcgag
    14881 tgcagaccgc ttactggctc ctttgaaatt tcctgatttt tttgaccggg gggtgtttaa
    14941 gattcgttca cctaacccca ccattcatct tttcggaaat ttctgtcatt cttatcaaaa
    15001 cgatcatgcc ttttattatg acatgctttg cacaatgttc gtaggttatc gatatcaagc
    15061 gcgaactctg gatataactc tagctccttg atatggtcaa cttctaaatt agtagtcgtg
    15121 accttgcctt catccctaca ccatacacat tcgtaatgat ctcgtttaag tgcttgcctt
    15181 cttatcgttc tccactcgct ggaattgtaa aactggttgc gctcttctcg agttgaaaca
    15241 tcaatcattt gattattgat gttgatactt tgagctcaaa tttatttagc ttgtcaatac
    15301 aattgttcaa gtgttcgatt gcttcacaac attgttgagt taactctttt aattctgagc
    15361 gattttcaat ttcgactcca actacaattt ttcctaatgg tttttgttta gtggttcttt
    15421 tattaaaaag tcttttaata atacctttca taactgtgca atctcctttg tttttactct
    15481 ttcaattcct tgttttacat attctagtga actcgctaca tgagttttaa ctcagcttta
    15541 tcaagcgttt atcttgcatg tgcgaaatga aatcatcata accttaaaac aatgaattga
    15601 tgttaaaata aaaaaattaa aagccctgaa atttcgtcat ggctctgtct tgtgaatctt
    15661 gatttttgcc gatataccga agtgaaatac tctggcttga gtgattcagt aggtccatta
    15721 tcagagcgac atccttggtt tgttcgtaca tgaataaacc aaaggtcttt ctcatagagt
    15781 gagtagctat gttttccaga ccaacttctt cagcagctct tttgataatc ttataagctg
    15841 tgttaggttt tatatgctga tgctttccgt ttcggcttgg aaagaggaag tcttcatctt
    15901 tcttatcttt tatgtactgc ctcatagcat tcttgaattt ctttggcatc tttcgtttgg
    15961 ttggcttgtc tgtcttttca tcgacgatct ggacatgcca acctttaacg tgctttactt
    16021 tcagtttaac gatatcacca atacgaaatc ccaaattaac accagaaagg aagagcatga
    16081 ggttgcgttg tctatctgac tctttgactg cactatgcaa cgtcagccat tcaatcataa
    16141 gctgaacatc atctctattt cggattggtt caacaactac cacatatcct cacctccttt
    16201 taatgcaaaa aaaagcagag gtttcctctc tgctattctt catgatacta atttaccaca
    16261 ttaaaattat catttgctat cattcttatc atacatttta gataatttta gtaacgcttt
    16321 atgttttgct cgttggatag tggcagggct acaatttagt tttatttgaa cttctttcca
    16381 agataatccg tcaatgtaca ataatcgcat cacgatgttt tccactggat catcgagcga
    16441 ctcaatcgct tgaacgagtt cgtcacgttc gtggtacatt tgtttgattt ctttatatag
    16501 ctgttctgac ttgtcaataa tcaacacatt caattcttca gtttgattct tgttactttt
    16561 tgattttggc atgctgtcga actgctgtcc tcgtaaaata cctgacttca aactgatgat
    16621 ttcttggtgc tttgacttag ctttgatatc gatataaggc aaagccttca atcttttttt
    16681 gatgtctatt gccaaatctt acctcctgac cgggttttcg tagatgttgc cgatgatttc
    16741 ctcatattcc gtccacgcat atccatctcc aaatcctttt aggtatacag caggcattcc
    16801 acctatgaat gtaccaccat attctttttc taaatatact tcatggagac atcctcttgt
    16861 acatttaacg atgtcaccga tgaatacctc cttgccgttc ttgtctctga gtcctgttga
    16921 ttgtcctaat gttgctggat ttacaggaca ccaagaacct atagtaatgt attgttcatt
    16981 ggcttctacc acttcgttga taataaatgc tcttcctcta tcttcaatta aatgtccgta
    17041 ttgccattct cctttgcttt tttcgtcaat ggataaccct ctaaattttg gtatcatgct
    17101 aacactcctt aaataaacaa actagctaac catatcaaaa atgcacatgt aatgattttt
    17161 gaaatactgc tctttaccgc atacgaataa tcctcttcag attctttttt gctagataac
    17221 acaggccaga tgaaagatag tagtgcatcc atccctaatg cttgccagac tgtaatttta
    17281 ccaactggaa caattgttgt gataatctca ttccatccat actgaactac aaatggcgat
    17341 acaacgatta caaataccgc cccaataatg attcctagtc ttttcatttt ataaatcctc
    17401 ctctttgacg aaagcaccat caatccaacg accctaccgt tttctaaatc acggtcaata
    17461 aaccattgtt tgactttctc tattgtgttc atgataactc ctttgctatt gctgctatga
    17521 cattaactgt cacgctattt cctgcttgtt tatataattg actgttagag ttgacctcct
    17581 gcgccttatc aaaagcccaa tcaggaaaac cttgtaacct ccagcattct ctaggtgtta
    17641 gctttctgat tcgaaagcca tctgataaat gattgttttc gtgatagcta ttgctagtta
    17701 aagtaggagc gatgtcatgt tctccacctt tattataacc atgcccacgt tgaataattt
    17761 taggctcaag tcctccacct tgataggctc tgatagttgg tgcgatgccg tctgtttcgt
    17821 aaaccacccc acattgatta aaattgggtt gcaatacccc aaattgtttt atagtattgc
    17881 tttttatagc tatcttttgc ccctctccct tgtttgttgt tagcgtggga gctagaccat
    17941 cagcttgata gacttcccca ttcattccgt tgccagatgg gtttatattc ccaattttca
    18001 tgactgattg gttactagtt gactgatttt ttccgctgag aggaaaaaat cttctggtac
    18061 gttctcttct aagatgtccg ataatgaaca ctcgttcccg attttggggg actccgaaat
    18121 tcttgctgtt aagcacttgc cattccacgt tgtaccccag ttcatccaag gttgagataa
    18181 tggtctcgaa tgtaactcca ttttcgtgat tgagcaatcc tttaacattc tcaaggaata
    18241 gatatttagg tctgagaata gatgcgaacc tagcaatttc aaagaacaaa gttcctcgtg
    18301 tatcttcaaa acctcgtctg tttcctgcaa ttgagaaagc ttggcacgga aatcctccac
    18361 agataatgtc cacacttccg attcctcgaa tagattcatc tgatactgct gtgatgtcat
    18421 gtaattctat ttctcctttc gtattgtgta tcgctttata gctttctcta gcaaacttgt
    18481 caatttcaca aaagccaata catttatggc cggcagactc cattcctaaa cgaaaaccgc
    18541 caattcctgc gaataaatcc aagaatttca caacatcacc tcatccccaa ctttcacttt
    18601 ctcatacacg ttcttcaaaa taactatgaa atttacttaa attgacaata gcgacctctt
    18661 caacagaatg ctttccgatg tcaaagtctg gatcattctt cccaaactct ttttctatag
    18721 ctttttcagc cagaaaaggc aaatcgaata tacttgcccc atttcttaaa gcgagcgctt
    18781 gaccgtattt gttcactatt cgatacccta tatcaaacgg tctgatttcc cttgggactt
    18841 ttatgcattt acttttattc ttcattcctt cttcaagtgt ttgtgtcatc actccacctc
    18901 ctcaatctca atacctgggc aatcaaacac ccagccgacc cctacttctt ctagttgttt
    18961 gcgagtaaat tttgtagcta gtccgcccat agagaagaat agtttcttat ccatagcatt
    19021 ataatatagc ggttgttttg ttgctttcgt cactactgta taccgcttct cttcctcgac
    19081 ctcgtagccg aactggtgca tgttgacgag ggtttgaata ggattttctc tgctattatt
    19141 aatccaatta ttaaactctc tattttctga ttttttagcc tcatccctga aagcaatcca
    19201 atcccaaaca ttaaattcaa aagaatcctt attctcttca taccaatccg ccacaaactg
    19261 cggtactacg actttaattt tggatttatc aacgatgtcg tctgtaatat aaatattatt
    19321 gttgggtaca ttgagagttt gcccgtattc caatctaaca acattttcaa cgcacttgtt
    19381 ctcatccaca tcaaaaccga ctattttccc tttcaagaga acttcatccc ctataaaaaa
    19441 gttaaagcgt ggtgtttcaa ttagatcttt attcattttc cacctcctct atatcaattc
    19501 cttcacaatc aaacacccag ccgaagtttg cgtcttctag ttgtttacgg gtgtgggaat
    19561 atataacatc gtctaaacta aagccttttg taaagaaata ccttttcaaa aattctccat
    19621 aaaccaacat attttcttta atattccctt taatcttaac aaaataccgc ttctcttttt
    19681 cgacctcgta gccgttaagc caagctagtg cgaagagttc ggaattatcc caataccatt
    19741 ctgcaactat gtcagacatg cttgcgtcta ttgagtagga cagtgtatga cccagttttt
    19801 tctgttctgc gataaaatcc gccacaaact gcggtacttt gactggttgc ggttcgccta
    19861 gttgttcaaa gatttctttt acatccttcc accaaactac ataaccttga aaattcctag
    19921 tcattgttct tcgttcctct aattttttaa tcaattcctg cttattcatc ttagtttcct
    19981 ccataaatca aataaactgc aataactacc tgagccatgc ttggcgaata gccaatccaa
    20041 tcatcaaact ccctagattt tggcaaccaa tccttagtag ctcccaaatc atagtctgta
    20101 ggcttttcat cagcaaagat gcattccatc gctcccataa acgtcatacc atcttctgcc
    20161 atttcccaaa aatagtccgc ccggtctttc accacttgtg gtaaatcttg cttgggaggt
    20221 tgcggcttcc cgtcttctac cgtccagttg tatactgcat taactttttg ctttaactct
    20281 tccatcatct tccaactcct ccaatttccg tctcaattct ttattctttt tcctcaacaa
    20341 atcgcgctcc agcgctctaa tccgtctctt gcgtgcatcg cacggcttcg aatactcgat
    20401 tatcttctct tcgttttgct cgatcgtgcg tttcagtccg tcaatctcag cctgtttatc
    20461 gtacttcatc ttctaaaaat ctttcaatag cttctctgta ggagacttcc accagaccgt
    20521 ctaagtcgtt cagggcttca atatagtctg gactaccttg cccgtactgc tctttcaaaa
    20581 attcaacaaa gagatgaatt tcctgatagg ttactccaac catgtttctt acctcccact
    20641 aaaaatgtaa cgttattgat catctttctt ttcctttctt gctacacgtt cctcgactaa
    20701 atagccgaga aataaccaca gaatagccat tccaaattct ttaataagtt caatcatttt
    20761 tttctcctcc tgaaaaagtc gctaaatagt aacaatcctt agagccgtag tcaaatcgtg
    20821 tcgtccgctg accaatgtgc ttctgaaatc ttggatgagt gatagccgag aaagcccact
    20881 gatgatcttc catctgttca atgagatcat cgacattgtc aaacgttcca aggtaaaact
    20941 tgcagtgccc gttgtagacg aagtaaagct ctaacatcac tccacctcaa cgggataaaa
    21001 attcccaaag gaacccctca atgccttacc aacctgtacg gctgccccac gagaaacaaa
    21061 ccgcatggct ttcttctcct cagaacatga aatgtccaag ccagtcacac cgataacagc
    21121 ggacatcaga aacggcttat cctctcttgt cccatgcttt aaaataaaca tcagccacct
    21181 ccattctaaa aatattgttt ccgcttgttc gtcaaatcat tgaaaaccat caaatggtct
    21241 ttatccaccc ccttcatcag tctggacata aagggtctgc catatctttt ctgaatatca
    21301 gcagaaatca aattcgtggt aatgattgta tttgaacgct tattcaggat attgtagaga
    21361 atagtaaacg accattcgct atccttctcc atgcccaaat catccaaaac caagaactta
    21421 gcgctagcaa tcttattgac cagaaactct tcctgactaa aatcagcttt aatcttcatc
    21481 agcaagtccg tcacattgat aaatatagca atctctttcg tgtactcaga taaagccttt
    21541 accatagcaa aggccaaatg gctcttgcca gttccagctt ctccttgtag cacgatgttg
    21601 ttcctagcac cctcagacca ctcacgacaa atcctctttg caaaaactag cttttccgct
    21661 tctttttcgg ttggcgtctc aaaattgtcc aaagtcgcat ttttcaaaac ctcatcataa
    21721 agagagaact tttcaagata gtatttcctc tctcgctcat tctcagcgtc ggccagttca
    21781 ttcactcttg cttgattctc ctcatggatc cgctcagatt cacacatgcg acatacaaca
    21841 ctttcagtcc gcaatatctt tatcaaaggg atgttatgct tttcacagaa ctcttcttgt
    21901 tgttctgtat tcctacgata agataaggcg atttcctcaa acacattgtc taccatacta
    21961 gtcgacctcc gcattcatgc cagctagcca tttcagacaa gcaggcaacc acttgatgaa
    22021 ttggttggtc tgctaaaaga gttttcttct cgtagcttaa cggataatag tcaatctcga
    22081 attgttcaat tagttctagt acccccattc gtccttggcc tcctgttctt ctttcttatc
    22141 cttgttcttc ttttccgatt gacgaacctg ttcaacagtg gtaacattgt tcatctgcca
    22201 atttcttaaa atcccaccaa tatatttgat gttcggcttt cctgagttaa tagcagtctt
    22261 caatgcttct ttcaccaaat ccacatcatt ctcatttagt agatggttga tttcttcaat
    22321 ttcaaatcca gataagagtc tacgaaactc agattgaaaa agttctaaga tattttcttc
    22381 actaccacta ctagtagtag ttattctttt cttattctta tctttatcta atctattctt
    22441 atctttatct tcttctagtg cgttaccgtc cgttactgta acgttacctg taacgttacc
    22501 aagagcaaga tttttttgtt ttttacggta tttggctaca cggttacgtg tctgttcctt
    22561 gattttctcc attccgtcaa cgttttgatg tttttcccaa tttggcaagc taataatacc
    22621 atcgataatc tcaatcatcc caaactgttc aaaaactcca atagccattc ttactgtatt
    22681 caatggtcta cgaaaaatag tagctaacat ttcatctgta tagtgaacct tatcagtcat
    22741 catcaacaaa ccattactgt tatgttttcc agcaagtgtc aaaatcttga accatatcac
    22801 taagatggca tcaggatcag gcaaggcatc aatcaggcaa atcttttcat cgtcaaaaat
    22861 atcggttgtg atttttatcc acttaatttc agacataccg agcaccccac ttcctgcgat
    22921 tggcacgata cttcatacgc atatcctcat agatgtgcct gccttccagc tccatttttt
    22981 caatctttag cagcttattt ttaagctcca catcacgata gtccttagct agtttttcat
    23041 agtctgttag gtattctttg actcgtaata gatttttata atcgttttcc catatcgtaa
    23101 taaaatgtct tgaagttgat tcccttcctt ccagttcttt aacaatcata atcaggttat
    23161 ccagcgattc aatcaattct tccatttcct gacctcctca ttacaaaaat ctgattccag
    23221 actgtttagg ttctggcaaa gctaacagct cagggcgcaa tcctacaggc ggttcgttgt
    23281 catatgtgaa tcctttgaac tctctgcgaa tattcttgcg aatttcttgc catttgtcct
    23341 ctctaccacg ttcatatgca tgattacgca cttggataat catatacgca aattcttgct
    23401 cttctcgtct ttcttcttcc ttgcgttgtt cctgcaattt gatatgacgg caagcccctg
    23461 caaatccaag cagcaaggct ccaaccccca tcagctggtc taaaatcggt ggttcaaaca
    23521 tttttatctc cttatcctct ttttgtgcta taatatagtc aaataatttt gctaagacct
    23581 tgtccagaag ccttttagta aagttattat atttgattag agagccattc tttgatggct
    23641 ctttttgacc atttcttacc aggtaattcc tttggaaatc cctttaagta acgataatta
    23701 tctgaaaatg tggcatactt aattcctaga aaatcacagg tagtgttcac atccatcagc
    23761 tctggatagt ggtcactatc tttttctatt tcgactagcc ttgtgattgt gtccttgata
    23821 atggatttaa tccattcaga cagtgaaagt agaacattgt ccatcttctt cccctcctac
    23881 ccttcgtcaa atgagttcaa ttccatgatt ttcatcttgg tattggtgct tggctcccaa
    23941 gtcatccaat aggccaaggc tgcatctgcg aattttttcg gtagcaagtc atagcgatta
    24001 atgttgaagt ggtctttaaa gtcaatctca gcttgtctaa agactgactg agcgaaagtc
    24061 ttatccgcat aagccggact atcaatgcca cctaagcaag ccacgacccg agccttacgc
    24121 ttcttcagta atgattgagc atagctagga tgaatcggtt gctcactctt gaggtagtca
    24181 atatcttcaa gcatggtaac ctgttgctca cgcaatttct tttgaccagt gaatagagcg
    24241 ataaaggcat cctcgtccaa gtcctcgcga atgaaaccgc cctgcttgcg aatagctggc
    24301 aaaacctctg atgtcaccca gcgcttaaac tctttagcct gaggcaactt gctggataag
    24361 ataagagagt agagaccaga ttcgttgatg ataatagttt cttggaccct tcctaaatta
    24421 tctgtgaggc cctgttttag ggcgtcatct tcatcaacat gaagagcaat cgcatttcta
    24481 gccttgctat atcctaggat gtctgcaaca tctttcccaa cgaaccaagg ctcgtcatca
    24541 attgtcaaag tacggacttc ctgcccgtga aaattaaaaa tttcgttcat aatattcctc
    24601 ttcttacttt tcctagtgtt aaaatagttt cccaaacatc tagtccctca agactatcga
    24661 tcatcatctg actaagttgg tgatttttct tctgccaatt cagtattatt ttcgcttgca
    24721 tgtatggacc tctcagtgat ttctccaagg gttttcaata cccaaaacat ctgcaacttt
    24781 ttccttaaca gactcactac ctttgccata cttcagcaac tctgaaataa ctgatgatgc
    24841 tacagatact tgttttgcca attcagcttg agtcatatcc aactcaatca aacgagtttt
    24901 gattttagcc ttgattatct ttagttcttt actcatcttt ctcctttcta tttcttcgtt
    24961 tcactttcca gcgctctgag ttctatctca tggctggctt gtttaaatag cttctcacac
    25021 gctattttag cttctctgta cgttgtgttc tcgctgatga agtaatcagc aagttcgatg
    25081 attttatctt ccattcaacc tcctatatca gtctcaagac tgaggtaata tcttcctaaa
    25141 ttgctataat aatcttgact aggacctctc accgttttag tcaaaattcc aatagaaagg
    25201 aggaaatttt atatgtcaaa actcactaaa gaagatgttt tacaagtttc tcaagaaatt
    25261 atcaacgatg ctattccagt tatccaagat atgttagatg aggtatttaa agaataccca
    25321 atcgacatgg aaattagaaa ggctattctt aatagcgtcc ttgtcgctca taaactcagt
    25381 acagaaacta cggtttcgtt gctaacagaa cttgtaaacg ctcaagaaaa ctagtgtttc
    25441 ttagaatttt ttctactaat tcagggtctg cctttacgag ggtagactct tttttcccac
    25501 tatacggata tcgtcttggt ctcatttcct cacctccttt taaaaaatta tctaaaaagt
    25561 tagcgaattt cttgacattg ataaataaat ttattaaaat caaaacatag agaaaagacc
    25621 tactaaaaag taaggttata cctagaaaac ggacgccaat cagtttcatt aggctttatt
    25681 ttttagttgt cttgttcgct aactctttag cttacaaaaa ctattgtagt aaatttatta
    25741 aactttgtca acagttttgt agtaaattta ttaaatattt tttgtcatgc cttagaaagg
    25801 ttgatgtatc aatgtttttc acatttgaaa aaataaaaga attggctgac aaacaaggta
    25861 tttcattaaa taaacttgaa gaaaaactag gttttagcag aaatacaatt tataacatga
    25921 agaaatccac accaaatgtt gaacgagttt caatgattgc tgactacttc aacgtgtcca
    25981 cagattattt acttggtcgc acggataacc caacaatcgc tggtagtcat gactacaaat
    26041 gggaaggtaa gactctaaac gttgaagaaa tggcatctaa tgtcatgatg tttggcggtc
    26101 gagaattaac agatgaaaag aagaaaatca tccagtctat cattgaaggt tatctcaaag
    26161 aagctggtga ttagaggtac tgcttagtga ctgaaaaaga aattataagt cattttcaga
    26221 ttcgtattat cgattttgat ggagatttga tgcctgatga acttggattt tacgaaaaag
    26281 aaaccaatac agctttcttg tctaacaaac tcagcaagaa agagagagtt aaagtactac
    26341 tgcatgaact tggacacaaa gaccacacac gctcagagta ccagaacgct cgcctacgct
    26401 gtgaaaacga agctgatagg aatatgatcc atcatctcgt aaaagacgcg atagaaagct
    26461 tagacgaccc cacagagttt gattacctca aattcatgtc ctactacaat ctaaaaacca
    26521 tgacgaatga agtcatggta aaagaggaat actttgcatt gatggagtga aaggagactc
    26581 atatgtctta ctcgtatgtt gctttagatg ttgaaactgc gaatgacttt cgcggtagtg
    26641 tttgttctat cggattagta aaatttaaag atggaaatat tgttgattct ttttacactt
    26701 taatcaatcc agaagaagag tttgatgatt tcaatatttt catccatggc attacacctg
    26761 aagatgttct tgattcacct acattcccag aggtgagaaa ggcgattgtt gattttattg
    26821 gttctgatat agttgtagcc cactttgcac agtttgatat gggtgctctt aaagatgtat
    26881 accaaaaata cgagctggat tttgataata tagaatatat ttgttcgtat cgattagcca
    26941 aggtcgctct ccctggacaa ttgaattaca aactaaaaag actagctaaa aatttgaata
    27001 ttgagctaga ccaccacaac gctttatcag atgcacgagc aagcggattg attttagaat
    27061 acttattatc tactaattca ttttccgacc tcaacgcttt tttaaaagaa tatagctaca
    27121 ataaaactgg cttacttggt cagtatggat ttaaaaggaa aaaaagttat cagtacaaag
    27181 aaaatcttat ctatcagcca acagaagaag aaaaggcagc aatgaaccca gaccattact
    27241 tttacggttt gtacttttgc tttactggaa aactcgagcg aatgactaga aaagaagcta
    27301 acaaagctac tgcattagtt ggtggtattc ctgaaaaagg agtgactaaa cacactaata
    27361 tcttagttgt aggagaacaa gattggagag tagtcggtac agatgggtta agtagtaaaa
    27421 tgaaaaaagc acaaaccttg ttagaaaaag gtcaagatat tgaaatcatg acagaaaatg
    27481 attttataag attgcttgag gagtaattaa caaaaaagct ccacaatctc cctcgccaaa
    27541 gtttgattgt gaagcccacc cttataaaaa atcagccatt aaaaaggcct cttttctata
    27601 ctctatttta caccatgaaa ggggtgatgt caatattctc aatgtttaga ccttgtccag
    27661 aagctgataa acaaggagaa tacaatgaaa tataataaaa caaaataccc aaatatctat
    27721 tactatgaga ctgctaaagg caagcgttac tatgtcagac gttctttttt cttccgaggt
    27781 aaaaaaagag aaaaaagtaa aagtggtttc acaactctcc ctcaagctcg cgcagccttg
    27841 gtagagcttg agcaacaaat tcaagaacaa gaattaggta tcaatacgaa tctaacgctt
    27901 gatcagtatt gggatatcta ttctgaaaag agattgtcaa cagggcgctg gaatgacact
    27961 tcctactacc tcaatgacaa tctctataag aaccatatca aggcaaagtt tggttctatc
    28021 ctgcttaaaa atttggatag aaatgagtat gaactattta tcgctgaaaa gttgcagaac
    28081 cataccagat acactgttca aaccctcaat tccagcttca tggcattgct gaatgatgcc
    28141 gtcaaaaatg gaaatctgct ctcaaatcgc ttgaaaggtg ttttcatcgg ccagagtgat
    28201 atccctgctg caaacaagaa agtgactctc aaagagttta agacttggat agcaaaggca
    28261 gaagagatta tgccaaaaca attctacgct ctgacctatc tgacaatttt tggattgaga
    28321 agaggagaag tctttggatt gcgtccaatg gacatcactc agaacgacag cggacgggct
    28381 atactgcatc ttagagacag tcgaagcaac cagaccttaa aagggaaagg agggcttaaa
    28441 acgaaggatt cagagcgata tgtctgcctt gatgatatcg gaacagacct gatctattat
    28501 ctgatagctg aagcttctaa gattaagcga aagttaggaa ttatcaagga acagcacaag
    28561 gattatataa ctatcaacga gaaaggtggt ctcatcaatc caaaccagct aaatagaaac
    28621 ttcaatctag tgaatgaagc aacaggattg catgtaacac ctcacatgat gcgccacttc
    28681 ttcacgactc aaagcattat tgcaggggtt ccgcttgaac aattaagcca ggcgctgggc
    28741 catacaaaag tctatatgac cgatcgttac aatcaagtag aggacgaact tgctgaagcg
    28801 acaacagacc tatttcttag tcatattcgc taaaaaagtc cccgccaatt ccccgaccaa
    28861 aatccgaaaa ataccgaaaa atatcgaaaa attattttta gaatagtccc caaaagcctg
    28921 aaataaagct aaaaaactcc acctgattgg gtggagtt
//
LOCUS       DAVLAQ010000025        25285 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000025 DAVLAQ010000000
VERSION     DAVLAQ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25285
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.025"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..1229
                     /locus_tag="VXB71_001130"
                     /pseudo
     CDS             1..1229
                     /locus_tag="VXB71_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1272..1913)
                     /gene="plsY"
                     /locus_tag="VXB71_001131"
     CDS             complement(1272..1913)
                     /gene="plsY"
                     /locus_tag="VXB71_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0451257.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            2049..3992
                     /gene="parE"
                     /locus_tag="VXB71_001132"
     CDS             2049..3992
                     /gene="parE"
                     /locus_tag="VXB71_001132"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0451258.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAVVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            4412..6883
                     /gene="parC"
                     /locus_tag="VXB71_001133"
     CDS             4412..6883
                     /gene="parC"
                     /locus_tag="VXB71_001133"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0451259.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            7015..8037
                     /locus_tag="VXB71_001134"
     CDS             7015..8037
                     /locus_tag="VXB71_001134"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0451260.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            8093..8797
                     /locus_tag="VXB71_001135"
     CDS             8093..8797
                     /locus_tag="VXB71_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0451261.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8862..9551
                     /locus_tag="VXB71_001136"
     CDS             8862..9551
                     /locus_tag="VXB71_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0451262.1"
                     /translation="MEWIRLIGIAIIVVGFIFKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9548..10471
                     /locus_tag="VXB71_001137"
     CDS             9548..10471
                     /locus_tag="VXB71_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0451263.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10486..11130
                     /gene="pcp"
                     /locus_tag="VXB71_001138"
     CDS             10486..11130
                     /gene="pcp"
                     /locus_tag="VXB71_001138"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0451264.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            11298..11528
                     /locus_tag="VXB71_001139"
     CDS             11298..11528
                     /locus_tag="VXB71_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0451265.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11578..11658
                     /locus_tag="VXB71_001140"
     tRNA            11578..11658
                     /locus_tag="VXB71_001140"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11612..11614,aa:Tyr,seq:gta)
     gene            11668..11739
                     /locus_tag="VXB71_001141"
     tRNA            11668..11739
                     /locus_tag="VXB71_001141"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11700..11702,aa:Gln,seq:ttg)
     gene            11901..13103
                     /gene="rpsA"
                     /locus_tag="VXB71_001142"
     CDS             11901..13103
                     /gene="rpsA"
                     /locus_tag="VXB71_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0451266.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(13188..14490)
                     /locus_tag="VXB71_001143"
                     /pseudo
     CDS             complement(13188..14490)
                     /locus_tag="VXB71_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14683..15180
                     /locus_tag="VXB71_001144"
     CDS             14683..15180
                     /locus_tag="VXB71_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0451267.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            15180..16835
                     /gene="dnaX"
                     /locus_tag="VXB71_001145"
     CDS             15180..16835
                     /gene="dnaX"
                     /locus_tag="VXB71_001145"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0451268.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            16863..17057
                     /locus_tag="VXB71_001146"
     CDS             16863..17057
                     /locus_tag="VXB71_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0451269.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            17207..17977
                     /gene="sufC"
                     /locus_tag="VXB71_001147"
     CDS             17207..17977
                     /gene="sufC"
                     /locus_tag="VXB71_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0451270.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            18005..19267
                     /gene="sufD"
                     /locus_tag="VXB71_001148"
     CDS             18005..19267
                     /gene="sufD"
                     /locus_tag="VXB71_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0451271.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            19278..20504
                     /locus_tag="VXB71_001149"
     CDS             19278..20504
                     /locus_tag="VXB71_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0451272.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            20491..20931
                     /locus_tag="VXB71_001150"
     CDS             20491..20931
                     /locus_tag="VXB71_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0451273.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20985..22397
                     /gene="sufB"
                     /locus_tag="VXB71_001151"
     CDS             20985..22397
                     /gene="sufB"
                     /locus_tag="VXB71_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0451274.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22596..23837)
                     /locus_tag="VXB71_001152"
     CDS             complement(22596..23837)
                     /locus_tag="VXB71_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0451275.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23940..25049
                     /locus_tag="VXB71_001153"
     CDS             23940..25049
                     /locus_tag="VXB71_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0451276.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         7730 a         4499 c         5580 g         7476 t
ORIGIN      
        1 tgattgatcg ttacggaata gagttcgtca aaaaaggaaa aaatcgttac tattctcctg
       61 atttaaaaca agaaatgatt aataaagtct gacatgaagg ctggactaaa gacagagttt
      121 ctcttgaata cggtctccca agtcgtacga tacttcttaa ctggctagca caatacagaa
      181 aaaaacgggt atactattgt tgagaaaaca agagggagag tacctaaaat gggacgtaag
      241 ccaaaaaaga gacctgaaga gaggacagaa ttagaacatc ttcaagcaga aaatgagtac
      301 ctgagagcgg agaatgccat cctaaaaaag ttaagagaac tccgattgaa ggaggaaaaa
      361 gagaaagaag aaagacagaa attgttcaag aattaatgac tgagttttcg ttagatattc
      421 ttctaaaagc cattaaacta gctcgttcga cctactacta tcacttgaaa cagctagaca
      481 aaccagataa ggaccaagag cttaaagctg aaattcaatc catttttatc gaacacaagg
      541 gaaattatgc ttatcgtcgg atttatttag aactaagaaa tcgtggttat ctggtaaatc
      601 ataaaagagt tcaaggcttg atgaaagtac tcaatttaca agctaaaatg cgacagaaac
      661 gaaaatattc ttctcataaa ggagacgttg gtaagaaagc agagaatctc attcaaggcc
      721 aatttgaagg ctctaaaaca atggaacagt gctacacaga tgtgactgaa tttgccattc
      781 cagtaagtac tcaaaagctt tacttatcac cagttttaga tggttttaac agcgaaatta
      841 tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg
      901 cattcacaga gaagcactac gagaatacga ttctccatag tgaccaaggc tggcaatatc
      961 aacacgattc ttatcatcag tttcttgagg gtaagggaat tcaagcatcc atgtcacgta
     1021 agggtaacag cccagacaat ggtatgatgg agtccttctt tgggattctg aaatcggaaa
     1081 tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa gccattgtag
     1141 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccctg
     1201 tgcaatacag aactaaatcc ttcggataaa ttaattgtct aactttttgg ggtcagtaca
     1261 gaactggcgt tttatttttt aggatcttga tgggttaggt tcaatcccca agggaccaaa
     1321 ttttcagttt tatttttgat acgagctata ttgtccttat gacgaatgat aatcaaacta
     1381 gcaagtgcta agataatagc gatgaagaga gagtcatagt tactcaggat aaaaccaaaa
     1441 agtggaaaga gcagaacccc gataacagcc gcgatcgatg ctgtgacact agacagtgaa
     1501 atcatactgc caagatagag agctccaaag aagataatcg caaggtagag acagaagata
     1561 ggcgcaaatc cgaaaatcac tccagcactg gttgcgacag ccttaccacc tttaaatcct
     1621 gcaaagatag ggaaggtatg gccgataaca gccaaaagtc caaagatgag aggagaaacg
     1681 ccttgtagat gaaaaataat cggaagcagc gttgctaggg ttcctttgaa aaagtcaatc
     1741 acaaaggttg ccataccagc tttcttacct aaaatgcgga aggtgttggt cgttccagtg
     1801 ttaccagaac catgctcgcg tagattgatt tgaaagaata cttgtccaat ccagagacca
     1861 gatggaatcg aacccagcag ataggctagg attaataaaa ctattgtaat catactccta
     1921 ttatatcatg aattgggaaa gaaaagcaga gaatctctgc tgaaattgtc acatcggaga
     1981 aagaaaaatt ttgcaaaatc cttggaaaac ctgtagaata gtaaagatga acgaatagga
     2041 ggttccttgt gtcaaaaaag gaaatcaata ttaacaatta taatgatgat gctattcagg
     2101 tgctagaagg gttggatgcg gtccgaaaac gtccagggat gtatattgga tcgaccgatg
     2161 gcgctggtct tcatcaccta gtttgggaaa tcgttgataa tgcagtcgat gaagccttgt
     2221 ctgggtttgg tgatcgtatt gatgtaacta tcaataaaga cggtagtcta acggttcaag
     2281 accatggacg tgggatgccg acaggtatgc acgctatggg aattccaact gttgaggtta
     2341 tctttaccat tcttcatgcc ggagggaaat tcggtcaagg tggctataag acatcaggtg
     2401 gacttcacgg agtgggttct tccgttgtta acgccctttc tagctggtta gaagttgaaa
     2461 ttacccgtga tggcgcagtt tacaagcaac gttttgaaaa tggtggaaaa cctgtcacga
     2521 ctttgaagaa aatcggtaca gcacccaagt ctaaaacagg caccaaagtt acttttatgc
     2581 ctgacgcgac tatcttttct acgacagatt tcaagtacaa taccatttca gagcgcctta
     2641 atgaatcagc ctttctcttg aaaaatgtga ccttgtcttt aacggacaag cgaacagatg
     2701 aagcgattga gttccactat gagaatggag tacaagattt tgtttcttat ctcaacgaag
     2761 ataaggaaat cttgacgcca gttctttact ttgaagggga agacaatggt tttcaagtgg
     2821 aagtagccct ccagtacaat gacggattct cagataacat tctatccttt gtcaataacg
     2881 ttcgcaccaa ggacggtgga acgcacgaga caggattcaa gtctgccatt accaaggtca
     2941 tgaatgacta tgcacgtaaa acaggtcttc tcaaggaaaa agataaaaac cttgaaggtt
     3001 cagactatcg tgagggacta gcggtcgttc tttctatctt agttcctgaa gaacacttgc
     3061 agtttgaagg acagaccaag gataaactag gaagccccct agctcgccca gttgtggatg
     3121 gaatagtggc tgataagttg acctttttcc ttatggaaaa tggggaatta gcttctaacc
     3181 tcatccgcaa ggctatcaag gcccgtgatg ctcgtgaagc agcacgtaag gcgcgtgatg
     3241 agagccgaaa tgggaagaaa aacaagaaag ataagggctt gttgtctggg aaattgaccc
     3301 cagcccaatc taagaatcct gctaagaatg aactctatct agttgagggg gactctgccg
     3361 gtggttctgc caaacaaggt cgtgaccgca agttccaggc tattctacct cttcgtggta
     3421 aggttgtcaa tacagccaag gccaagatgg cggatatcct caaaaatgaa gagattaata
     3481 ccatgattta taccattggt gcgggtgttg gagcagactt ctctattgaa gatgccaact
     3541 atgataagat cattatcatg accgatgcgg ataccgacgg tgcccatatc cagaccttgc
     3601 tcttgacatt tttctaccgt tacatgcgtc cgctagtcga ggcaggtcat gtctatattg
     3661 ccctcccacc tctttataag atgtccaaag gtaaaggcaa gaaagaagaa gtggcctacg
     3721 cttggacgga cggagaacta gaagaactcc gtaaacagtt cggtaaaggc gctaccctcc
     3781 aacgatacaa aggacttggt gagatgaatg cggaccagct ctgggaaaca accatgaacc
     3841 cagaaacacg taccctcatc cgtgtcacaa ttgaagattt agcgcgcgcc gaacgccgcg
     3901 tcaatgttct catgggagat aaggtagaac cacgccgtaa atggattgaa gataatgtca
     3961 agtttacgct agaagaagcg acagtgtttt aatgaaagaa aataatatgt tagtaaactg
     4021 gaaattagag tcggatgtga atgactatgt gaaaaagcag tttgaaaatc ttggtttgaa
     4081 aaaattgcag gattattaat gaagaatctg ctatgagtgc ttatctcaaa gaggcgctta
     4141 agggagcggc taagacacaa actaagacta attttggaaa accagatttt catattgaaa
     4201 aatacaaaca ggatagtttg gttacttatc gtaactgaac acgggaggaa ttcccgtaaa
     4261 atatctttta ctgcataaaa acctactcta cattctttga aaggagttga acacgcccta
     4321 gatactgtgt gaaaaagata aattctcttg tgagtttgct tacttcaaga attttctatt
     4381 ttcacttggt attttatggg ctttgtatct tatgtctaac attcaaaaca tgtccctgga
     4441 ggacatcatg ggagagcgct ttggtcgcta ctccaagtac attattcaag accgggcttt
     4501 gccagatatt cgtgatgggt tgaagccggt tcagcgccgt attctttatt ctatgaataa
     4561 ggatagcaat acttttgaca agagctaccg taagtcggcc aagtcagtcg ggaacatcat
     4621 ggggaatttc cacccacacg gggattcttc tatctatgat gccatggttc gtatgtcaca
     4681 gaactggaaa aatcgtgaga ttctagttga aatgcacggt aataacggtt ctatggacgg
     4741 agatcctcct gcggctatgc gttatactga ggcacgtttg tctgaaattg caggttacct
     4801 tcttcaggat atcgagaaaa atacagttcc ttttgcatgg aactttgacg atacggagaa
     4861 agaaccaacg gtcttgccag cagcctttcc aaacctcttg gtcaatggtt cgactgggat
     4921 ttcggctggt tatgccacag acattcctcc ccataattta gctgaggtca tagatgctgc
     4981 agtttacatg attgaccacc caactgcaaa gattgataaa ctcatggaat tcttgcctgg
     5041 accagacttc cctacagggg ctattattca gggtcgtgat gaaatcaaga aagcttatga
     5101 aactgggaaa gggcgcgtgg ttgttcgttc caagactgaa attgaaaagc taaaaggtgg
     5161 taaggaacaa atcgttatta ctgagattcc ttatgaaatc aataaggcca atctagtcaa
     5221 gaaaatcgat gatgttcgtg ttaataacaa ggtagctggg attgctgagg ttcgtgatga
     5281 gtctgaccgt gatggtcttc gtatcgctat cgaacttaag aaagacgcta atactgagct
     5341 tgttctcaac tacttattta agtacaccga cctacaaatc aactacaact ttaatatggt
     5401 ggcgattgac aatttcacac ctcgtcaggt tgggattgtt ccaatcctgt ctagctacat
     5461 cgctcaccgt cgagaagtga ttttggcgcg ttcacgcttt gacaaagaaa aggctgagaa
     5521 acgtctccat atcgtcgaag gtttgattcg tgtgatttcg attttggatg aagtcattgc
     5581 tcttatccgt gcttctgaga ataaggcgga cgccaaggaa aacctcaaag ttagctatga
     5641 ttttacggaa gaacaggctg aggctatcgt aactttgcaa ctgtaccgtt tgaccaatac
     5701 cgatgtggtt gtcttgcagg aagaagaagc agagcttcgt gagaagattg ctatgctggc
     5761 ggctattatc ggtgatgaaa ggactatgta caatctcatg aagaaagaac ttcgtgaggt
     5821 caagaagaaa tttgcaactc ctcgtttgag ttctttagaa gacactgcga aagcaattga
     5881 gattgataca gctagtctta tcgctgagga agatacctac gtcagcgtga ccaaggcagg
     5941 ttacatcaag cgtaccagtc cacgttcctt tgcggcttcc accttggaag aaattggcaa
     6001 gcgtgatgat gaccgtttga tttttgttca atctgccaag acaacccagc acctcttgat
     6061 gttcacaagt cttggaaatg tcatctacag accaatccat gagttggcag atattcgttg
     6121 gaaggacatc ggagagcatc tgagccaaac catcacaaac tttgaaacga atgaagaaat
     6181 cctttatgtg gaagtactgg atcagtttga cgatgcgaca acctactttg cagtgactcg
     6241 ccttggtcaa atcaaacggg tagagcgaaa agaattcact ccatggcgga cctatagatc
     6301 taagtctgtc aagtatgcta agctcaaaga cgatacagat cagattgtag cagtggctcc
     6361 gattaaacta gatgatgttg tcttggttag tcaaaatggt tatgccctgc gtttcaatat
     6421 cgaagaggtt ccggttgtcg gtgctaaggc agcaggtgtc aaggctatga atttgaaaga
     6481 agatgatgtc ctccaatctg gctttatctg taatacttcg tccttctacc tcttgaccca
     6541 gcgtggaagc ttgaaacgtg tttccattga ggaaattcta gcaaccagcc gtgccaaacg
     6601 aggattacaa gtcttgcgtg agttgaaaaa caaaccgcat cgtgtcttct tggcaggagc
     6661 agttgcagag caaggatttg ttggcgattt cttcagtacg gaagtggatg tgaacgacca
     6721 aactctgctt gtccaatcca ataaaggaac aatctatgaa agccgattgc aagacttgaa
     6781 cttgtcagaa cgcactagca atggaagctt catttctgac acgatttcag atgaagaagt
     6841 ttttgacgct tatcttcagg aagtagttac tgaagataaa taagtgaaat gaagaatcag
     6901 ttctaagagc tggtttttat tggagaaatt ttctgaaaat tacaaaatat acttgctatt
     6961 ttagaaaaat agtgtagaat ataagaaata ggtttttaga ataaggagtg gaatatgaca
     7021 gtaacgattg attgggaaaa cctcggtttt tcctatatga aattacctta tcgctatctt
     7081 gctcatttca aaaatggaca atgggatcaa ggagagctta cagaggatgc aactttgcat
     7141 atttcagagt cttctccaag tcttcactat ggacaacaag catttgaagg tttgaaagct
     7201 tatcgtacta aggatggcag tgttcaactg ttccgtcctg atgaaaatgc taaacgtctg
     7261 caacgtacat gtgaccgtct cttgatgcca caagttccga cagacatgtt tgtagaagct
     7321 tgtaaagcag ttgtccgtgc gaatgaagaa tacgtaccac catacggaac aggtggaacc
     7381 ttatatcttc gccctctttt gattggtgtc ggagatatta tcggggtaaa accggcagaa
     7441 gagtacattt tcaccatctt tgctatgcca gttggaaatt actttaaagg tggtttggtc
     7501 ccaaccaact tcttgattca ggatgagtac gaccgtgcag caccaaatgg tacaggtgcg
     7561 gctaaggttg gtggaaacta tgctgcaagt ctcttaccag gaaaaatggc caagtcacgt
     7621 catttctcag atgttatcta tctggaccca tcaactcata caaagattga agaagtcgga
     7681 tcagctaact tctttggaat tacagctgat aatgaatttg taacaccatt gagtccatct
     7741 atcttgccat ctattaccaa gtattccttg ctttatttgg cagaacatcg cttgggatta
     7801 actcctattg agggtgatgt tccaattgat aatcttgacc gttttgtaga ggcaggtgcc
     7861 tgtggtacag cagcggttat ttctccaatt ggaggtattc aacatggtga tgatttccat
     7921 gtattctata gtgaaacaga agtaggtcct gtgacgcgta aattatataa tgaattgacg
     7981 ggtattcagt ttggcgatat tgaagcgcca gaaggttgga ttgtaaaagt agattaaaat
     8041 aaaccaaagg agatttttta tgaaatagaa aaagtggctc ttaacagcag gagtggtcct
     8101 gagcacgtca gctattttag tggcttgtgg aaaaactgat aaagaagcag atgcaccgac
     8161 aacattttct tatgtctatg cagtagatcc agcatcattg ggctacagta tagcgactcg
     8221 aacatcgagg acagacgtta ttggaaatgt tattgatggt ttgatggaaa atgataaata
     8281 cggcaatgtt gctccttctc aaaaagacta tgatttgaat agtacaggat gggctccaag
     8341 ctatcaagat ccagcgtctt acttgaatat tatggatcca aaatctggtt ctgccatgaa
     8401 acaccttggt attacgaaag gaaaagataa ggatgttgta gctaaacctg gtttggataa
     8461 atataagaaa ttgttagaag atgctgtttc tgagaccact gacctagaga agagatatga
     8521 aaaatatgcc aaagctcaag cttggtcgac agatagttca ttattgatgc caacagcttc
     8581 atctggtggt tctccagttg taagtaacgt agtaccattc tcaaaaccat actcacaagt
     8641 tggtattaag ggggaaccat atatctttaa aggaatgaaa ttgcaaaaag atattgttac
     8701 aacaaaagaa tataacgagg tttttaaaaa atggcaaaaa gaaaaattgg aatccaatag
     8761 caaataccaa aaagaactag aaaaatacat taaataagga atggtattga tcttgataaa
     8821 atttttaaaa tactgtcatt ttgaatataa aggagtttga tatggagtgg attagattaa
     8881 taggaatagc aatcattgtt gtgggtttta tttttaaatt tgatacaatt gcaacagtag
     8941 tcttagctgg tttggttaca gctttagttt caggtgtttc tctcgttgaa tttttggaga
     9001 ttttgggaaa agaatttagc aatcagcgag tgctcacgat ttttatggtt accttgcctc
     9061 ttgtggggct gtcagaaacc tttggactca agcaacgatc aatcgatttg attcgaaaga
     9121 ttaaaggtct gacagttgga aacttctata cagtttattt ttttattcga gagttagctg
     9181 gtttcttttc aattcgtcta ggaggacacc ctcagtttgt cagacctttg gttcaaccta
     9241 tgggagaagc agctgcagag tctcaattag gtagaaagtt aacagaggtt gaagatgaga
     9301 caataaaagc gcgtgcggct gcgaatgaaa attttggaaa tttctttgct caaaatacgt
     9361 ttgtaggtgc tgggggagtc ctcttgatag ggggaacatt agatcagtta ggctatgaaa
     9421 gcaattatgc agggattgct tctacatcta ttattgttgc tgttataaca cttattgtag
     9481 tggggattta caattattta tttgataaaa aattgatatc aaaaaagact aggggaggag
     9541 aacaaaaatg acagagttgg caaagcaact attagagttg acctatattg tgattggttg
     9601 tcaatttctc catacagcct attgtagtta taaagataaa acaaacccag ttcgacttgg
     9661 gacatctgca ttttggactc tattgtctat tacgtttata ggtggttcct atatgccaaa
     9721 tatgagtatt ggtattattg taatcctatt atcgctgtta acattgttta agcaagtccg
     9781 tatcggaacc ttgccatcct tagatgaaat gaaagccaat attgaatcta acaggttgaa
     9841 aaataaaatt tttattccag ttatgctgat ggcaatactt gcgttggtct tagcgcaaat
     9901 gattccagaa tttagcaaga tttcgattag ccttgccgcc ttgtttgcta caatttctgt
     9961 tcttgtgatt accaatagtc accctaagag tctgttatca gaaaataatc gaatgactca
    10021 gcaagtttca acaagtggta ttgttcctca attattaggg gctttggggg ctatttttac
    10081 tgtagcaggt gttggtgatg ttatctctca tctgattagc ggtattgttc cttcagatag
    10141 tcgctttata ggagttttgg cctatgttct tggaatggtt ctattcacaa tgattatggg
    10201 aaatgctttt gcagcattca ccgttattac agcaggtgtt ggagttccct ttgtatttgc
    10261 tctgggagct aatccaattg tggctggtgc tcttgccatg acagcaggtt attgtgggac
    10321 cttattgacc ccaatggctg ctaattttaa cgctctacca gcagcattga tggatatgaa
    10381 agatcagaat ggcgttataa aggctcaagc aggtgttgct ctagtaatga ttgttattca
    10441 catattctta atgtactttc tcgcatttta gtaaaggaaa ataaaatgaa aatattggtt
    10501 acaggtttta atccttttgg aggtgaaaag attaatccag ctttggaggc tgtaaaatta
    10561 ttaccatctg agattaatgg ggctgaagtt cgctgggtag aaattccaac ggttttttat
    10621 aagtcgtcag aagttttaga ggcagaaata ttacgatatc aaccagatgc tgtactttgt
    10681 attggacaag caggcggcag gaccggctta acacctgaac gagtggctat taatcaagat
    10741 gatgctcgca tacctgataa cgaaggcaat caaccaattg atacaccgat tcgtattgat
    10801 ggagcatcgg cctattttag tagtttacct atcaaagcga tggtacaagc tatcaaaaaa
    10861 cagggacttc cggcagttgt atccaatagt gcaggaacct ttgtttgcaa tcatttgatg
    10921 taccaagctc tttatttagt ggataaaaaa ttccctaata tgagagcagg tttcatgcat
    10981 attccatata tgatggaaca agtagtaaat aagccgaata ctgcaggaat gagtctatgt
    11041 gatattgtaa gaggcataga ggtagctatt gaagctattg tagactacaa agataaggat
    11101 ttgcagttag taggcggtga gactcactga taacctaaaa aggatagtca attatgcttg
    11161 tttactaact attagctatg ctaaatcgat tgaggttgtt tacataaaac tctatatcag
    11221 agaagcctga tatagagttt tttcttgcta gttttaggat tttcttgtaa aatagaaaaa
    11281 gtgaagagag gtatgaaatg agcaagaaag ataaaaaaat cgaaattcaa gtagcggatg
    11341 ccaaagttaa tgttggtaaa gacagttttg aaggttatac attgactatc ggtaaaaaag
    11401 ttatcggaga aattgccgaa ttagacggac aatttgccat tataaagaat gggaatgtcg
    11461 atagttttta taaaaaattg gaaaaagctg tggaaatttt gattgaaaat tataatttag
    11521 caaaataagt cttgtttttt tgaaattttc atgatataat agtccatgtt gattgtagga
    11581 gagatagcga agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt
    11641 cgaatccctc tctctccatt tcattaatgg ggtatagcca agcggtaagg caagggactt
    11701 tgactccctc atgcgttggt tcgaatccag ctaccccagt tcttaggtaa taatcaagat
    11761 aaaaagcaaa atatcttagg gtattttatt tttataattg aaagacgtga atgatatgaa
    11821 catgtccttg cgggtgctta ggaaaaaaat tataagtatg tcaagtttaa gaaaaacttg
    11881 attgttggag gattttttag atgaacgaat ttgaagattt gctaaatagc gttagtcaag
    11941 ttgagactgg tgatgttgtt agtgctgaag tattgacagt tgatgcgact caagctaacg
    12001 ttgcaatctc tggaactggt gttgaaggtg tcttgactct tcgcgaattg acaaacgatc
    12061 gtgatgcaga tatcaatgac tttgttaaag taggagaagt attggatgtt cttgtacttc
    12121 gtcaagtagt tggtaaagat actgatacag ttacatacct tgtatctaaa aaacgccttg
    12181 aagctcgcaa agcatgggac aaacttgttg gtcgcgaaga agaagttgtt actgttaaag
    12241 gaacgcgtgc cgttaaaggt ggactttcag tagaatttga aggtgttcgt ggatttatcc
    12301 cagcttcaat gttggatact cgtttcgtac gtaacgctga gcgttttgta ggtcaagaat
    12361 ttgatactaa aatcaaagaa gttaacgcta aagaaaaccg cttcatcctt tcacgtcgtg
    12421 aagttgttga agcagctact gcagcagctc gcgctgaagt attcggtaaa ttggctgttg
    12481 gtgatgttgt aactggtaaa gttgctcgta tcacaagctt cggcgctttc atcgaccttg
    12541 gtggtgttga cggattggtt cacttgactg aattgtcaca tgaacgtaac gtatcaccaa
    12601 aatcagttgt aactgttggt gaagaaattg aagtgaaaat ccttgatctt aacgaagaag
    12661 aaggacgtgt atcactttca cttaaagcaa cagtaccagg accatgggat ggcgttgagc
    12721 aaaaattggc taaaggtgat gtagtagaag gaacagttaa acgtttgact gacttcggtg
    12781 catttgttga agtattgcca ggtatcgatg gacttgttca cgtatcacaa atttcacaca
    12841 aacggattga aaatccaaaa gaagctctta aagttggtca agaagttcaa gttaaagttc
    12901 ttgaagttaa cgcagatgca gaacgcgtat cactttctat taaagctctt gaagaacgtc
    12961 cagcccaaga agaaggacaa aaagaagaaa aacgtgctgc tcgtccacgt cgtccaagac
    13021 gtcaagaaaa gcgtgatttc gaacttccag aaacacaaac aggattttca atggctgatt
    13081 tgtttggtga tatcgaactt taatcaaatt gaaaattcac aaaatccttt gtttactaaa
    13141 caagggattt ttctggctct ttgtcaactg tagtgggttg aagtcagcta aggttgagaa
    13201 aggacaaatt tcgtcctttc ttttttgatg ttcagagcga taaaaatccg ttttttgaag
    13261 ttttcaaagt tccgaaaacc aaaggcattg cgtttgataa gtttgatgag attattggtc
    13321 gcttccaatt tggcgtttga atagggtagt tgaagggcgt tgacgatttt ctctttgttc
    13381 tttagaaagg ttttaaagac agtctgaaaa agaggatgaa cctgcttaag attgtcctca
    13441 ataagtccga aaaatttctc tggttcctta ttatagagct gatagtggtg tttcaagtct
    13501 tctgaatagc tcaaaagctt gtttaaaatc tctttattgg ttaagtacat acgaaaagta
    13561 gaacgataaa atcgcttatc actcagttta cggctatcct gttgaatgag tttccagtag
    13621 cgcttgatag ccttgtattc atgagacttt cgatgaaact gattcatgat ttggacatgc
    13681 acacgactca tagcacggct aagatgttgt acaatatgaa agcgatcaag aacgatttta
    13741 gcattcggga gtgaaacagt ctgagagact gtttcagcct gagcctagaa atttgaaagc
    13801 gaagttgtct agctaagtca tagtaaggac taaacatatc catagtaatg attttcactt
    13861 gacaacgaac ggctctatca tatttaagaa agtgatctcg gatgatagct tgtgttctac
    13921 cttcaagaac agtgatgata ttgagctttt caaaatcttg cgcaataaag ctcatctcca
    13981 tctcccgatt gaaacagtca ctccccggac tgtttcaacg tcccaagaca taatctcagg
    14041 cagatttcta aaattacact caaagtggaa gtcattgagc tttcgaatga cagttgaagt
    14101 tgagatggaa agctgatggg caatatcggt catagaaatc ttttcaatta acttttgagc
    14161 aatcttttgg ttgatgatac gagggatttg gtgattcttc ttgacgatag aagtttcagc
    14221 gaccatcatt tttgaacagt gatagcactt gaatcgacgc tttctaagga gaattctagt
    14281 aggcatacca gtcgtttcaa ggtaaggaat tttagacggt ttttgaaagt catgtttctt
    14341 catttgactt ccgcactcag ggcaagatgg ggtgtcataa tccagtctag cgatgatttc
    14401 cttgtgtgta tccttattga tgatgtctaa aatctggata ttagggtctt taatgtctag
    14461 taattttgtg ataaaatgta attgttctat atgattcttt ctaatgagtt gttttgttgc
    14521 ttttcattat aggtcatatg ggactttttt tctacacaaa ataggctcca taatatccat
    14581 aggggattta cccactacaa atattataga gcccaaaatc ctttgtttac taaacaaggg
    14641 atttttcttt tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa
    14701 caatcacgtt atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat
    14761 gttttggcta atctttccaa cgccagtgct ctcataaaat cacgttttcc taataccgta
    14821 tttgcaggct tttatttgtt cgatggaaag gaattggttt taggcccctt ccaaggaggt
    14881 gtttcctgca tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag
    14941 gaaactgtta ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta
    15001 gctaaaagtg aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat
    15061 ctggattctt cagagattga ggattacgat gctatggatc gagattattt ggaacaattt
    15121 gtcgctattt tgcttgaaaa gacaacatgg gactttacga tgtttgagga aaaatcttaa
    15181 tgtatcaagc actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag
    15241 aagttgtggc taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc
    15301 ttttttctgg tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta
    15361 tgaactgtcc caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag
    15421 tgacggacgg tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag
    15481 atgaaattcg cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg
    15541 tttatatcat agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga
    15601 cgctggaaga accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga
    15661 ttcctgctac tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg
    15721 atattaagga acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg
    15781 ctgtggaaat cattgccagg cgggcggaag gtggaatgcg ggacgccttg tctattttgg
    15841 atcaagccct gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta
    15901 ctggcaccat tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg
    15961 ttcccaaagc tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt
    16021 ttgtgaccga tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa
    16081 atactcatca tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg
    16141 aaatgattcg cttagcaaca gtgagtttag cagatattaa gtctagtttg cagcccaaga
    16201 tttatgctga aatgatgacc gtccgtttgg cggaaatcaa gcccgaacca gctctatcag
    16261 gagcggttga aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc
    16321 tttctaatgt aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg
    16381 gcaaaacagt ctatcgtgtc gatcgcaata aagtgcaatc tatcttacaa gaggccgtcg
    16441 aaaatcctga tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa
    16501 ttgaaagtct aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca
    16561 atgaacacca tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac
    16621 gagacaatct caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg
    16681 agattttagc tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag
    16741 ccaaatcttc tcaaactgaa aaagaagtag aagaaagcct gattccagaa ggatttgaat
    16801 ttttggctga taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt
    16861 ttatgaataa acaacaattt attattatgg cgctgtttac agctgctgag acctattttt
    16921 tcaatgaagc ctggatgact ggccgctata ttatggcagc cttttgggca attttactct
    16981 ttagaaattt ccgagtcagt tatgtgatgg gcaaaatcgt tgatgtcatc gatcagcatt
    17041 ttaataggaa agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt
    17101 tgttatacta gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt
    17161 ttttctagta agtactgtaa aagttttgaa aaagaaagga actatcatgt cagtattaga
    17221 gattaaagat cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac
    17281 cctgaaaaca ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct
    17341 ttctgccgct atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga
    17401 tggcgtaaac atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc
    17461 tatgcaatac ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat
    17521 gaatgcgggt aaagaaggtg atgagaagat ttcagttcgt gagtttatta ctaagctaga
    17581 tgaaaaaatg gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg
    17641 cttctctggt ggtgagaaaa aacgcaatga aattcttcaa cttttgatgt tggagccaac
    17701 atttgctctt ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc
    17761 taaaggtgtc aatgccatgc gtggtgaagg ttttggtgct atgatcatca ctcactacca
    17821 acgtcttttg aactatatca cacctgatgt ggtacacgtg atgatggaag gtcgtgttgt
    17881 cctttctggt ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaattagc
    17941 tgaagaactt ggctacgact acaaggaaga attgtaattt cctcgtatct tttaggagaa
    18001 gtaaatgact agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt
    18061 ggctgatctc cgtcaaaaag cttttgacaa gattgagact ttggaattac cagttattga
    18121 gcgtgtcaaa ttccaccgtt ggaatctggg tgatggaacg attacagaaa atgagccatc
    18181 agcaaatgtt ccagatttca cagctttaga tcatcacttg aagttggtgc aagtaggaac
    18241 tcaaactgtt ttcgaacaaa ctccagttga gttagctgaa cagggtgttg tcttcacaga
    18301 ctttcactca gctttagaag aaattccaga gctgatcgaa gaattcttca tgtcatctgt
    18361 taagtatgat gatgacaagt tggcggctta ccacacagct tactttaaca gtggtgctgt
    18421 actctatatt ccagataacg tagaaatcac agagccaatt gaaggaattt tctaccaaga
    18481 tagcgatagc aatgtgccgt ttaacaagca tattatgatt atcgctggta aaaattctaa
    18541 gattagttat ctggagcgtt tagagtcacg cggtgaagga agtgacaaag caactgccaa
    18601 tatcacagtg gaagtgattg cacgttctgg tgcgcaagtc aagtttgctg ctattgaccg
    18661 tctaggtgaa aacgtcactg cctacattag ccgtcgtggt aaattaggca acgatgcaag
    18721 tattgactgg gctatcggtg tcatgaacga aggaaatgtc gttgctgatt ttgatagtga
    18781 cttgattggt aatggtagcc atgctgacct caaggttgta gctctttcaa gtggtcgtca
    18841 ggtacaaggg attgatactc gtgtaactaa ctatggctgc aactctatcg gaaatatcct
    18901 acaacatggg gttatccttg aaaaagcaac tttgactttc aatggtatcg gccacatcat
    18961 caagggtgct aagggagcag atgcccaaca agagagccgt gttctcatgc tttcagacca
    19021 agcgcgttca gatgctaacc caattctttt gattgatgaa aatgacgtca ctgcaggaca
    19081 tgcagcctct attggtcagg tagatccaga agatatgtac tacctcatga gtcgtggatt
    19141 ggataaggca actgcagagc gtttggttgt tcgtggtttc cttggatctg ttatcgtgga
    19201 gattccagtc aaggaagttc gtgatgaaat gattgcaact atcgaagaga aattgtcaaa
    19261 acgctaaggg gaagcctatg ttagatgtag aagcgattcg caaggatttt ccaattttag
    19321 atcagattgt caatgatgaa cctctggtct atctggacaa tgctgcgacg acacaaaaac
    19381 cactagtagt tctgaaagct attaacagtt actatgagca ggacaatgcc aatgttcacc
    19441 gtggtgtcca taccttagcg gaacgagcga cagcttctta tgaagctgct cgtgaaacca
    19501 ttcgtaagtt tattaatgca ggctctacaa aggaagttct ctttaccaga ggaacgacaa
    19561 ccagccttaa ctgggtggca cgctttgctg aggaaattct cactgaggga gaccaggtct
    19621 tgatttcagt aatggaacac cattctaata tcattccatg gcaggaagct tgtcgaaaga
    19681 ctggagcaga gcttgtctat gtctatctta aagacggtgc cttggatatg gaggatttgc
    19741 gagctaaatt gactgataag gttaaatttg tttccctagc tcatgcctcc aatgttcttg
    19801 gtgtggtcaa tccgatcaag gaaatcactc aattagccca ccaagttggg gcaatcatgg
    19861 tagtggatgg tgctcaatct acacctcata tgaagattga tgtccaggac ttggatctgg
    19921 actttttcgc cttttcgggt cacaagatgg ctggtccgac tggtatcggt gtcctttacg
    19981 gcaaagaaaa gtatcttgag caaatgtctc cagtagaatt tggcggcgag atgattgatt
    20041 ttgtctacga gcaatctgct agttggaagg aattgccttg gaaatttgag gctggaacgc
    20101 caaatatggc aggagctatt ggacttgcga ctgcagttga ttatctggaa aagattggta
    20161 tggatgccgt tgaagctcat gaacaggaat tgattgcgta cgtctatcca aaactgcagg
    20221 caattgaggg attgaccatt tacggttctc aggatttggc tcaacgttcg ggtgttattg
    20281 cctttaacct aggtgatctc catcctcacg atcttgcgac agctctggat tatgaaggag
    20341 tggctgttcg tgctggtcac cattgtgcgc aacccttgct tcagtatttg gaagtcccag
    20401 caacagctcg tgcaagtttt tatatctata ataccaaggc agattgcgac aaactagtcg
    20461 atgccctaca aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat
    20521 atggcagtgg tagcagacca ttcgaaaaat ccacatcacc aagggaagtt agaagacgct
    20581 gagcaaatca gtctcaacaa tccgacttgt ggagatgtca tcaatctctc tgtcaagttt
    20641 gatgcagagg accgtttgga agatattgct tttctaaatt caggatgcac gatttcaact
    20701 gcttctgcta gtatgatgac agatgccgtt ttaggaaaaa ccaaacaaga aattttagaa
    20761 ctggcgacta ttttttctga aatggttcaa gggcaaaaag atgagcgtca agaccaactt
    20821 ggagacgcgg cattcttgtc aggtgttgcc aaattccctc aaagaatcaa gtgtgcaacc
    20881 ctagcttgga atgcccttaa gaaaacaatt gaaaatcaag aaaaacagta agacaagttt
    20941 cttttgtctt atgaattatt agaaatgaag aaagaaagga tattatggct gaagaaagag
    21001 tagaaccaaa accaattgac cttggtgaat ataaatttgg tttccatgac gatgtagagc
    21061 ctgtcttatc gacaggaaaa ggactcaacg aaggtgttat tcgtgaatta tctgctgcta
    21121 agggtgagcc tgagtggatg ttggagttcc gtttgaagtc ttatgaaacc ttcaaaaaaa
    21181 tgcccatgca aacttgggga gcagacttgt cagagattga ctttgatgac ttaatctact
    21241 accaaaaacc atctgacaaa ccagcccgtt cttgggatga tgtacctgaa aagattaaag
    21301 aaacctttga acgtatcggg attccagaag ctgaacgtgc ttatttagca ggggcttctg
    21361 cccagtacga gtcagaagtg gtttaccaca acatgaagga agagttccaa aaattaggta
    21421 ttatctttac agatacagat tccgcactca aggaataccc agacttattt aatcaatact
    21481 ttgcgaagtt ggtaccgccg acagataaca agttggcagc cctcaactca gcagtatggt
    21541 cgggtggaac ttttatctac gtgccaaaag gtgtcaaggt agatattcca cttcaaactt
    21601 atttccgtat caataacgaa aatataggtc agttcgaacg taccttgatt atcgttgatg
    21661 agggagcaag cgtccactac gtagaaggat gtacagcacc aacatattca agcaatagct
    21721 tacacgctgc cattgtagaa atttttgctt tggacggagc ttatatgcgt tatacaacta
    21781 tccaaaactg gtctgataac gtctataact tggtaacaaa gcgtgctaag gctcaaaagg
    21841 atgccactgt tgagtggatt gatggaaact tgggtgccaa aacgactatg aaatatccat
    21901 ctgtttacct tgatggagaa ggagcgcgtg gtaccatgct ctctatcgcc tttgctaatg
    21961 cagggcaaca ccaagacacg ggtgctaaga tgattcacaa tgctccacat accagctcgt
    22021 ctattgtgtc taaatccatc gctaaaggtg gaggaaaggt tgactaccgt ggacaagtca
    22081 cctttaacaa gaactctaag aaatctgttt cccacattga atgtgatacc attatcatgg
    22141 atgacttgtc agcatcagat actattccat ttaatgaaat tcacaactcg caagtggctt
    22201 tggaacacga agccaaagta tctaagattt cagaagagca attgtattat ctcatgagcc
    22261 gtggattgtc agaatctgag gcaactgaaa tgattgtcat gggatttgta gaacccttta
    22321 caaaagaact tccaatggaa tacgcagttg agctgaaccg cttgattagc tatgaaatgg
    22381 agggatcagt tggataaaat ttgattttat actcttcgaa agtctcttca aaccacgtca
    22441 gcatcgcctt accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac
    22501 agtgttttga gcaacctgcg gctagcttcc tagtttgttc tttgattttg aagatgaact
    22561 tgtatcaaaa aatcgcggtt taaaatcgcg attttttata atttctcgtt aacaaagcgg
    22621 acaaactgat tccaccaaac ttttaagaag aaggcttttt caattttctt gtctgctacc
    22681 atttcgaaac tagggcgctc tgtggtgatg taaccttgac caatcaagtc cttgtcttca
    22741 taagtcaaat ggccaaccac tgttccagct tcaagtggtg ctgggattgc tttggaatca
    22801 ggtgtgaatt gaacagattg ggaagattga ttcccaacac gttctattag atagatatcc
    22861 tctggagcca ctgcagttac tgtatcttct tttccatctt gtacaggggt tttgctatct
    22921 tgataggcat cgccttgttg aacgattttg cgaagtgtaa atgtagaaga aatataatcc
    22981 attagggaag atgtagctgt aaatcgagcg taaggattat tgtcttgatg atctgcattt
    23041 aaaacaactg tgatgactct catgcctttt tcgacagtag taccaacaaa agactctcca
    23101 gccttatctg ttgttcctgt ttttagccca tcaaaaccac cacggtaagc aggcatacct
    23161 tctaacatgt agttggttga agtgattgtc atcccagcaa aagtagaaga aggttttttg
    23221 gtgatttcta agacttgtgg gtattttttg atgaggttgc gagcaacgat agcgacatca
    23281 taagcactaa gcttattttc ctcatctttt ttagaacctg ggtaaatgtt atcccctaga
    23341 gtttcattgt taagacctgt cgtattgaca acagtggcat cctgaattcc ccattccaag
    23401 agttttgccc gcatcatatc gacgaaatct ttttctgagc cagcaatttt ctcagctagg
    23461 gcaatagcgg cgctgttggc actagatacc agagttgctt caagcaactc ttcgacagta
    23521 taattacggg cctccatagg aatattactg gcttcagaat ttgtcgtcaa ttgataagga
    23581 taatcagaaa tatctacagg agtggagagg gtaatacttc cgttttccaa agcttcatag
    23641 accagataaa cagtaatcaa ttttgttatg gaagcaattt cgacaggttg cgttgcatcc
    23701 ttctcataga gaattttacc agtatttgcc tcaacagcaa tcgcatgttt agcggcaatg
    23761 gtaaaatctt gagcaacagc agtagaagca ccccctaaaa gagagacagt taacaaagtt
    23821 aaaaatattt ttttcatagt agtcttattc tatcataaag aaaaaaaata ttcttgcttt
    23881 aataattcat ctgttaagct ttttgaaaat atggtaaaat aaagtgaggg aggtaactca
    23941 tgtttcgtag aaataaatta tttttttgga ccacagaaat tttactctta accatcatct
    24001 tttacctatg gagacagatg ggatctttga ttaacccttt tgttagcgtg cttaatacaa
    24061 ttatgattcc atttttatta gggggctttc tttattattt gacaaaccct attgttactt
    24121 tcttaaataa agtctgtaaa ctcaatcgtt tgcttggtat tttaattacc ttgtgtactt
    24181 tggtctgggg aatggtcata ggtgttgtct atctcttacc tattttgatt aatcagttat
    24241 ctagtttgat tatatctagt caaactattt atagtcgagt acaagactta atcatagact
    24301 tatctaatta tcctgcgctc cagaatttgg atgtagaagc tacaattcag cagttaaact
    24361 tatcctatgt tgatattctt caaaatatcc taaatagcgt atcaaatagt gtggggagcg
    24421 tcttgtcagc tcttatcagt actgttttga ttttgattat gactccagtt tttttggttt
    24481 atttcttatt agatggacat aaattcttgc ccatgcttga aagaacgatt ctaaagaggg
    24541 atcgcttgca tattgcaggc ttattaaaga atttaaatgc gacgattgct cgctatatta
    24601 gtggagtttc gattgacgca atcattatag gttgtttggc ttatattggc tatagtatta
    24661 ttggtttaaa atatgcttta gtttttgcca ttttttctgg tgtagccaat ttaattcctt
    24721 atgtggggcc aagtattggt ttgattccta tgatcatcgc aaatatattc actgatcccc
    24781 atagactgct gattgcagtg atttatatgc ttgttgttca gcaggtagat ggcaatatct
    24841 tatatcctcg aattgtagga agtgttatga aggttcatcc aatcacgatt ttagttttac
    24901 ttttgttgtc aagcaatatc tatggtgtag ttggaatgat tgtcgcagtg ccaacctatt
    24961 ctatcttgaa agaaatttct aagttcttat cccgtttgta tgaaaatcat aaaataatga
    25021 aagaacgaga aagagaatta gctaagtaaa agtcaggaga accctgattt ttctttactg
    25081 gaagtggcct ttagattaga agactgaaaa taagttaaag tcttaaacta attttcacag
    25141 ctaagaatag tagaagttaa tctgataaaa atcgaaaaaa ccagtggaat tccgtgtcag
    25201 ggtaagttcc actggttttc atagtctatt aaagttcgaa tgaaacctat ttataatata
    25261 ttgaaactag aatagtacac ctcta
//
LOCUS       DAVLAQ010000026        24380 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000026 DAVLAQ010000000
VERSION     DAVLAQ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.026"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            111..275
                     /locus_tag="VXB71_001154"
     CDS             111..275
                     /locus_tag="VXB71_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0451277.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            359..925
                     /gene="amaP"
                     /locus_tag="VXB71_001155"
     CDS             359..925
                     /gene="amaP"
                     /locus_tag="VXB71_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0451278.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            937..1107
                     /locus_tag="VXB71_001156"
     CDS             937..1107
                     /locus_tag="VXB71_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0451279.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1146..1754
                     /locus_tag="VXB71_001157"
     CDS             1146..1754
                     /locus_tag="VXB71_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0451280.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1785..1988
                     /locus_tag="VXB71_001158"
     CDS             1785..1988
                     /locus_tag="VXB71_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0451281.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2098..2376)
                     /locus_tag="VXB71_001159"
                     /pseudo
     CDS             complement(2098..2376)
                     /locus_tag="VXB71_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3140..3910)
                     /locus_tag="VXB71_001160"
     CDS             complement(3140..3910)
                     /locus_tag="VXB71_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0451282.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3925..4773)
                     /locus_tag="VXB71_001161"
     CDS             complement(3925..4773)
                     /locus_tag="VXB71_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0451283.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDNFEDPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTGLDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4770..6245)
                     /locus_tag="VXB71_001162"
     CDS             complement(4770..6245)
                     /locus_tag="VXB71_001162"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0451284.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVNFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6568..7923)
                     /locus_tag="VXB71_001163"
     CDS             complement(6568..7923)
                     /locus_tag="VXB71_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0451285.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLNQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWHAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7933..8250)
                     /locus_tag="VXB71_001164"
     CDS             complement(7933..8250)
                     /locus_tag="VXB71_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0451286.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8267..8584)
                     /locus_tag="VXB71_001165"
     CDS             complement(8267..8584)
                     /locus_tag="VXB71_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0451287.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8599..9495)
                     /locus_tag="VXB71_001166"
     CDS             complement(8599..9495)
                     /locus_tag="VXB71_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0451288.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9498..10760)
                     /locus_tag="VXB71_001167"
     CDS             complement(9498..10760)
                     /locus_tag="VXB71_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0451289.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11040..12218
                     /locus_tag="VXB71_001168"
     CDS             11040..12218
                     /locus_tag="VXB71_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0451290.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12446..12892)
                     /locus_tag="VXB71_001169"
     CDS             complement(12446..12892)
                     /locus_tag="VXB71_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451291.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
     gene            12962..13621
                     /locus_tag="VXB71_001170"
     CDS             12962..13621
                     /locus_tag="VXB71_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0451292.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWKLLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTCHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13673..14824)
                     /locus_tag="VXB71_001171"
     CDS             complement(13673..14824)
                     /locus_tag="VXB71_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0451293.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14839..15570)
                     /locus_tag="VXB71_001172"
     CDS             complement(14839..15570)
                     /locus_tag="VXB71_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451294.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            15799..15900
                     /locus_tag="VXB71_001173"
                     /pseudo
     CDS             15799..15900
                     /locus_tag="VXB71_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(15872..16648)
                     /locus_tag="VXB71_001174"
     CDS             complement(15872..16648)
                     /locus_tag="VXB71_001174"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0451295.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(16641..17864)
                     /gene="trpB"
                     /locus_tag="VXB71_001175"
     CDS             complement(16641..17864)
                     /gene="trpB"
                     /locus_tag="VXB71_001175"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0451296.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(17842..18441)
                     /locus_tag="VXB71_001176"
     CDS             complement(17842..18441)
                     /locus_tag="VXB71_001176"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0451297.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(18428..19195)
                     /gene="trpC"
                     /locus_tag="VXB71_001177"
     CDS             complement(18428..19195)
                     /gene="trpC"
                     /locus_tag="VXB71_001177"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0451298.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(19192..20196)
                     /gene="trpD"
                     /locus_tag="VXB71_001178"
     CDS             complement(19192..20196)
                     /gene="trpD"
                     /locus_tag="VXB71_001178"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0451299.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDVRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(20207..20773)
                     /locus_tag="VXB71_001179"
     CDS             complement(20207..20773)
                     /locus_tag="VXB71_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0451300.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(20770..22131)
                     /gene="trpE"
                     /locus_tag="VXB71_001180"
     CDS             complement(20770..22131)
                     /gene="trpE"
                     /locus_tag="VXB71_001180"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0451301.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNSFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGVTDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(22678..22755)
                     /locus_tag="VXB71_001181"
                     /pseudo
     CDS             complement(22678..22755)
                     /locus_tag="VXB71_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     misc_binding    complement(22921..23150)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23362..24363)
                     /locus_tag="VXB71_001182"
     CDS             complement(23362..24363)
                     /locus_tag="VXB71_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0451302.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         7633 a         5208 c         4007 g         7532 t
ORIGIN      
        1 ttgatttttt gatattaaaa taaaaaagga gggtaggcag tgttgtgatc aattattgct
       61 ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa aagtagttct atgggaatca
      121 tcgcaaatgt attcgctggt ttagtcgggg catatgcagg acaatctctt ttaggtagtt
      181 ggggtccatc aatcgctgga atggctttgc tcccatctat tgtaggtgca gcgattgtga
      241 ttactgtagt gtcattcttt acaggtagaa agtaaacttt tcgccagtaa agttagcaaa
      301 ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag gattgtatat
      361 gtcaaaagca aagaaaatat gtttcattat tttctgtatt ttaatcttga caattttcct
      421 tcctgttttg atagattatc atcaagttag tgatctaggt attcatctac ttagctggag
      481 acagaactcc gtagttgaat tctatcttgc tagatatgtc ttttggggga cagtggttct
      541 atcaacttta gttttattat ccattttagt tgtgatgttt tatcctaaac gttacttgga
      601 aatccaactt gaaactaaaa acgatacatt aaaattaaag aattcggcaa tcgaaggttt
      661 tgttagaagt ttggtgagtg atcatagatt gatcaagaac ccaactgttc atgtaaattt
      721 acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag acaacatcgc
      781 tgacagatgc caaataattc aaaatgaaat aactaatgga ttgaagcagt tttttggtat
      841 tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac caaccaaaac ctcaaaacaa
      901 aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa acaatatcga
      961 tatccaatta tcgctggtct cataggcgta tttctggctt gtttgattgt ctcctttggc
     1021 ttcttcaaaa caatatttgt attgatttta ggagcactgg gagttgcagc tggattatat
     1081 atcgaaaaaa actatataga taaataaaaa aataaaaatt actaatttaa ttaaaggagt
     1141 ttcatatgtc aaacgaaaaa aacacaaaca ctaacgtaga aaagaaagat gctactgttg
     1201 tagctcacga aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg
     1261 gtctttcact agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc
     1321 ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta
     1381 aaacacaagt tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt
     1441 tatattcaga aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa
     1501 ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact
     1561 cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag
     1621 aacaattcga aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag
     1681 ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca
     1741 ctcgtgtaaa ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa
     1801 aattaaatca agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa
     1861 aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gtcgccgaag
     1921 atgccaaaga cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg agtggcgacg
     1981 ataaataagg ttaaaagtta ctttatcttt ttagtaacat tagtcaaaag agtctgagtc
     2041 aagatgattc tcagaaaaca aaaagctaga gattcccaat tgcggaactc tagcttttta
     2101 attttgcctc tttctcttat tatatttcag caggttgttg gccatgagta tgaatcccat
     2161 gtcaattctc acttgacgct tacctctcag atgacatctc ttataaccca aacaaacctt
     2221 tatctgccca aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt
     2281 ggaagataaa agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata
     2341 cagtcccttt tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct
     2401 gtttgctttc tatctcccct ttttcatgat atattttcgt acaggtgctt caatagtttc
     2461 tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata atgttcttgt ggcatattca
     2521 ttagattttc gtaaaaagtt ctctcctatt tgtgagcgaa caggtatagt caattgattg
     2581 tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc agaatccatc caagggtggc
     2641 tggcacaatt tctagtgaac ctctttaaat ctattacgtt tgactgtgga aaagagtttt
     2701 caaaatggaa agatatttcc aatcatcacg atagtgagag cttttttgcg aatctaggat
     2761 gtccaagata gcggtgtctc aacgaacatt caaatagact tttaaggtgt catgacttgc
     2821 caaagcagac agatttcaac gaagtcagtc aagaatttta ggctgggcaa gaactcaatt
     2881 tcaggagaaa atgaaataaa tattcccaca ataaaacgca tagtatcaaa gtttttccaa
     2941 cacctgatat tatgcatttt ttaattttaa agactttttc ccagcctcaa gaaatcacat
     3001 cccacctaaa tcctttggat accaaatacc tcatcaggtt attttctgag ttggtaagac
     3061 tgtctagctt aatttgacaa atggagggcg ttaaatccag tttttacagg aagtctattt
     3121 aaatattttc acactgacct tacaaaatat gaaataaatt atataaagtc attcccatga
     3181 caaagaataa catcccttta aaacagtatc ttacccaatt ttcaggtaag acttttgata
     3241 caaccgtccc caatacccct ccgcatatag aagcaagaaa aataactgga acaggtgcta
     3301 aatgatactg atttaaacct gtaaccacaa caattgtagc caaatgagac agctgggaaa
     3361 agaaaataat tgcaagagaa tacatcgttg cttcttttat cgaaatagaa aaaaacacca
     3421 tcaataaaga tacattgagc ggacctccac caatccctaa aaaactagaa atcaagccca
     3481 atagaagacc acaaatcata tagaatccta tcttatcaaa ttgataagtt tttttaaaat
     3541 ctgttaaaac aaatgataca agtagcatca caaatagtaa aatcatttga acaatggata
     3601 ctagccgtac tgataattga gataacaaaa cttgaaaaat aagatgacct agaaatcctc
     3661 ctaaaacaga agaaaaggat accgtaaaaa tcaatctcca ttttatctct ttactttgtg
     3721 aaaatctttt ggttgttgaa ataatcgcca ttataaaaac agagaaacta gaataaaaag
     3781 caatatcact gaccgaatgg tatccaaaac tatccataag tggcttaatt ataattccac
     3841 cacccatgcc tgatatagaa cccaatccac tagctattat aatgattaga aaataaataa
     3901 tctcaaccac tttttaagtc catcctattc tttcaaacat ctaaaaccta gatggctact
     3961 agtggaagta gaaatacatc catttctagc agctactcgg tatcgattac aataagaaca
     4021 atgacataaa aaggaacctc ctctgatagc atactcctca tcttgtatcc catattttgg
     4081 caactcatag tcatcttcat taaaactagc taataaggta tatctcggat tgcgacacca
     4141 ttcccaaaca ttcccaatca tttgatatag accaaaatca ttaggtaaaa attcatagac
     4201 aggagccgtt cctataaatc catctaagcc agtattttca taaggaaatc ttccttgcca
     4261 agtattggca tgataatatc caccttctaa aagagtatct ccccaaggat attcagattg
     4321 tcttcctcct ctagcagcgt attcccactg tgcttcagtc ggtaaagaca ttccgctcca
     4381 attacagaaa gccaatgcat cttctaaagc aacatgaact actggatggt cttctaaacc
     4441 cactagatta ctgttctcac cgtagggatg tttccagcaa gcgttcggaa cttgtaacca
     4501 ccacggagcc ccggcaggat gaggatatcc ctccctttct gcctccggaa cgaacaatat
     4561 aaaaacaaaa gaccactctt gtcgctcagc tagtgtttta tagcctgttt ctttcacaaa
     4621 ttgagcaaat tcttgattcg taactggagt atccgcaatg gaaaaatcct ttacactaac
     4681 agcgacttga ggatcttcaa aattatctaa aaagccctct tcagaatttg ttcccatcat
     4741 aaatgtccca cccttgattt ttttcatttt catgattgac tatcccccgt tttcgttaga
     4801 gttggcgtta ttttagaaag ttcaacagga actaactctt catccacaac aaaaccttct
     4861 tctctatatc taagaaagtt tactaatttt ttcttcatct gacgaacaat aggttggtat
     4921 ttttcacttg gatacaaatc attcatttca tgcggatctt ttttcatatc aaataactga
     4981 taatgattta aaacaggaaa ccagataaat ttccactggt ctgtcaaaat atattgacta
     5041 gaatcttttc ctaaagcatg ttcaccatga aattctgttc gccacccctc gtactgtcca
     5101 aataataaat tcttaacact ccgtccatct agttcatctg tagtagttcc tcctgccaaa
     5161 tccacgagtg aaggaaaaat atcttgaatt ttcactaatt gcttgattgt tcccctatta
     5221 ccagctatca atccagccgg atcgtaaata aacgaaggaa tgtggatact tccctgataa
     5281 ggatatccct ttctaaacag ataatgttca ccaagctgat ctccatgatc cgaaacaaac
     5341 cagataatcg tatctttatc atgacgaaat tcttttaggg cagtcaaaaa gcgactaatt
     5401 tgatggtcta tatgagtaat caatccaaaa taagcagcaa ccattcttct ttgatcatct
     5461 tcctttaatt tccctcttaa agcataaata gacggaattt gcttttctaa tacttcccaa
     5521 ttcccgatat gcaaatcgag aaattgaggc aagcgttcca tatacatatc aaaatagtat
     5581 tttgggggat ttaatggagc atgtggtttt tcaaaagaca ttttgagaaa aaaaggaacc
     5641 gttggatctc ttctttgtaa aaatgaaatg gactcactca caacccagtt tgttggatgt
     5701 aacttttcat ctttatccca aggtctagct tcccaagaat tacaatccat tccgtcatca
     5761 atcaaatcaa catcataacc aactttaccc tttaaaaagg ctagatagtc actagcataa
     5821 tcaaattgac ttccataagc cttatcatac tttctatcaa catgtagata cccatcgtga
     5881 agtaagacat gatcaaaccc aagtctctgt ctggaaggaa aaacatgcat cttaccaata
     5941 cactctgttt gataacccat atctttaaag acttttggaa gagtattagt aaaattccaa
     6001 ggcacctcat cttgataacc aacacgtcca cttttatctt ggtctaagcc agtcaataaa
     6061 gctgccctag caggaacgca agaaggaact ggagaatagg cattttcaaa attataacct
     6121 acactagcca tcatatctaa tgttggagtg ctaactagct tatccttact attcaaggat
     6181 aaggcgtctg ctctcatttg atctacaaca atcaaaataa tatttggctg ttttgtctga
     6241 accataaaat ctcctttcta atatggcaaa agaggcacaa gaagatatct acctttactg
     6301 cacccctttc tatatcaatc tctctatata aaacaataac attcttgtta tgttttatat
     6361 aaaaatgaac taaaatatga ctaaatcgat taggaaattc aaatcatttt ctagtactgt
     6421 tttagaagtt acagtgtact attccaactt caataaacta taaacctttg tctattaaca
     6481 attttagtgg agataagaaa tcctacacct aactcatctt acacgtaatc tatttctatt
     6541 ttatcacaaa aaacgcaagt aagaccatta actcaattca gttttatctg ccattttcac
     6601 aaatgggaaa taagtcaaga cactaataat caaacaaaca actgataaga tgatggcatg
     6661 ccaatcaaat gctgtagaga agaaaccata taaaattgga ggcattaccc aagtaacatt
     6721 ttgtgtaaca ggtgaaacaa gaccccagct tgttgcccag taagctaccg ttgccatgaa
     6781 aaccgggcta agtacaaatg gtataaatag caaaggattc aagacaactg gtaaaccata
     6841 attgaccggc tcaccaatat taaacagaac tggtgctaga ccaagtttag caacttttcg
     6901 ataatgactg tttcttgaaa aaattaaaat agcaagtact aatcctaatc ctccaaacca
     6961 gacaaacgcc ccaaaagacc cacttgtcca tatataagga atcggttcac ctttttggaa
     7021 agcatccaga ttcgctaaca tagcaactcc aaatagccct tccatgatgg gagccaatac
     7081 atttcctcca tggagaccaa aaaaccagaa taacttattc aaaaagatca tcagaataac
     7141 tgcaaagaaa ctttgagaca aacctagtaa tggcgtttgt aacaccttgt aaacccaatc
     7201 aatcaataag tcattgctaa gtaaatggaa aacataagtc aagatggcta ctatatacat
     7261 cgccataaat cctggaatga tagaagtgaa cggcttagca atcgcagggg gaactgaatc
     7321 tggtaacttg attacccagt tctttttcat tactttacag aaaataatag aggctaaaaa
     7381 tccaatcatc atggctgtaa agtatcctct ggcattaata tggtttcctg gaatcacatt
     7441 cccaatagtt accatcagat ttttaccatc aaatgctaga ttatcaattc cttgtaagat
     7501 ttgatttaat ttcacatctc ctacatttgc caaagggaaa ctctttgtaa ctgtacttcc
     7561 aatcgaaatg acaaacgaag caagtgatac caaaccagca gaaactgtat caaccttgta
     7621 aatcttagcg atattcactc ccaagcaata gatgaacaat aaggaaacaa ttggtatact
     7681 tcccttgaat accaaattat tgatgtcaac aagccactga aaggttttcg taatactttc
     7741 taggtgaaat tgttgtggta aatccactag aaaagcattt aataacaaag caatggaacc
     7801 tgtcataata acaggcatag tccccacaaa tgaatcacgt aaagcaacta aaaacttctg
     7861 attcccaact ttcattgcaa ttggagaaag tttttcttgc attttatcca acattgtatt
     7921 catagcaaat tcctaatttt tttcaaatcg ttcgtatact tctaccactt ctttcgccaa
     7981 gtcaacaaag gtcagactcg tcattaaatg atcttgcgcg tgtaccatca agaggctaat
     8041 tgaagtttct tccccctgtg cctctcttgt caacatttct gtttgagcct tatgcgcctg
     8101 taataaggca gcattcgcat cagctaatct tcgattggct ttagagaaat cccctttttt
     8161 tgctgcctga atagcctcca tagcattact tttggcttcc ccaccataca taattagccc
     8221 cattgcagat tctaaattac tttcattcat agcattctcc tcaatcttag tctaataaac
     8281 tttcagctaa atctaagact ttagaaccat tcatcattcc ataatctgtc atcggaataa
     8341 ccgccacagg aatctgtcta tcttttagtt tttcttgaaa gtcccctagt aaatagcgaa
     8401 cttgagggcc taaaagcaac acatttactt cctttgttgc tacaatttct tctgcttcag
     8461 gagctggaac tgcaaaaatt tctgcatcca accccttatc ttctgctgcc ttttgcatct
     8521 ttgtcactag cagacttgta ctcatacctg ctgcacatgc taacataatt gttactttag
     8581 ccatagctta ctcctttatc acctatttac tgacctagcc aagcgagata ctgtatgtct
     8641 cactcctcta attgccttgc tcaatgcata aatattatcg actgttgcca gtcccccata
     8701 tcctgcgtca cctatatgtt gaatatcaac tccacaaatt ttatttctaa gtgcaatttc
     8761 cttgatagta tctgtatcag atgtttcttg gctagtacca atagcactca gtactagccc
     8821 acccttacta tgaacgagat caacgacttc acgcaactct tggtcatgaa aggctggaac
     8881 ggttccaact gctggaacaa gtatcacatc cgcacctgct tccaacaatt gctctgctac
     8941 agaaagctct gccacaggct cattcactcc tgccccgtgc atcttacctg caataatcaa
     9001 accagaaaag ttttccttag cagtttgaac agccttaatg atttctcgat tgctaactcc
     9061 tgttccagga tttccagtca aacagacaaa gtcaaaacct aactcctcta ttcgattcaa
     9121 tgtttcaaca ctagcaacac gacctgcaac aatttcctgt gtttcctcta gcatctttgc
     9181 agatgggtca atcggttcca aatttacacc aattggacaa gcaacaagct ggtgtaagcg
     9241 atgaataaca tcatcacctg aactatccaa agcataaatt ttaggctcaa aaacatcaac
     9301 acaattcaat aaaatcatat cagctccaaa agctctagca atttcagaat tagttatatc
     9361 cccaacaaat gtctcacgag taactacatt ttcagataga acaactctac cttcacttgc
     9421 taaaatactt tgttttaatt cttcagcatt catctgtaat atctcagatg gatttgcact
     9481 aattaaacgt ttcattctca atcctccaat aacttaaacc gtttttcaat agctattaca
     9541 aatggtaaat aaagtaagac atccaaaaca atcaatacaa tttgtaataa tgaaccagaa
     9601 atacttcctg tagcaagtaa accacttata acaggtggca tagtccaacc tggatctgta
     9661 taagttagcg gaaccaaacc tgatgccatt gctccccacg ctactagtaa gttaaacatt
     9721 ggagctaaga taaatggaac tagtaacaaa atgttcaaaa caataggaac gccaaacatt
     9781 gctggttcat ttatattaaa taatccaggt ataacagtta taggtgccaa agtttttagt
     9841 tgtttactag ctttcttctt atgtgctaaa tatcctaacg caagaactaa acctatggtt
     9901 gcaccaccgc cacctatgaa tacaaaatta tccataaata cgctagtaaa aatatttgga
     9961 agagtttctc cagtttgata agctacttta tttgcatcta gattagctaa ccataacggt
    10021 ttcataactg cattaacaac atttcctccg tgtaatccta caaaccaaaa actactatta
    10081 aggaaaatta agataagaag accaataaca ttatttccta aaagtccaag tggacctccc
    10141 aaagctactt gagcaatttc atgaagatta ggtaaactta atttatctaa agttgcataa
    10201 acaatcaacc aaccaacaat agtcactgca ccaggaataa tggcactaaa gcttttagat
    10261 actgctggtg gaacaccatc cggcattttt atctgtatat tatgatttat aaaccattgg
    10321 tagatatagc cattaatcaa tcctaaaatc atagcaacaa ataaaccttt tgatgccatg
    10381 aaagcggtag gcattcctgc tccagcctct cctctaatga aaggcgtaac tgtaataaaa
    10441 gatgataatg acacaatacc agcaggaata ccatcaactt tgtattgtct agccataaag
    10501 taagcgatac caaaactagc tacaagacca agtaatccaa aactactatc aacacccttc
    10561 cataaatagt cagcaacacc aatatcaccc agatattttt cccatcctgg aataggaaaa
    10621 cttgcaataa ccattagtaa tgaacctatc aacaataaag gtatagttag agtaataccg
    10681 tctcgaatag aaaccaacgc tttattatta cccaatctag ccgctactgg aagtaacttt
    10741 tcttgtaata atttttccat aaccttttcc tcttaaatat attttattat caaaagttat
    10801 caattatctt tattttttga cgtcaagttg ttatttgatt atcttttgtt atttatattt
    10861 tacaactata agaaagcctt gtcaaggatt tgtgtaaata tttgattatt ttttattatc
    10921 aatatataat aaaaagagac cagtaagcaa tgaaaagctt aaaaagatta acatctacat
    10981 ttatccatag caaaaaatca taggatttta agaatctgac aactaggaag aaaactaata
    11041 tgaccttatc taagaaacaa ttacaactac gagctaaaat actggaaaca gtttacacat
    11101 taggtcccat ttcacgaatt gaaatcgcta ctaaaacagg aataacacct gcaacaacta
    11161 gcagtatcac aaatgatctg attaaagaaa acattctctt agaacttggt gaagacgaac
    11221 acgatacaag cgtagggaga aaaaaaatcc tgctagacat tcaagctaaa cgattttact
    11281 acattggttg tgaactatct gaaaaacatt tcacttttgc tttaggagat aatctaggaa
    11341 atatcttaaa ggaagagaaa gaaattgtta ctaaacagtt aatccaagaa aagggaaatc
    11401 aactcattag ccagacacta aagcaattct taaataactg ctctgattat gaaatagaag
    11461 caattggaat cgcgctacct ggtcgctatt tagatgatta taaaataaca acaaacaatc
    11521 ctttatggca acatatcgac ttagaaatga ttcaatccca ctttgataag cctttgtttt
    11581 tctctaacaa tgttaactgt atggctatag gtaaacgcct atttagtcgc caacagaatg
    11641 accctaattt tgcttatttt cattttgcta gaggtatgca ctgttcttat atctacgacg
    11701 gaaacattta tggaaaagga aatctaatga ttggagaaat agggcataca gttgtttcat
    11761 ctgagggaga agaatgtagt tgcgggcgca agggatgctt acaaactttt gctggagaat
    11821 cttggttaat caaaaaatca aaaattctat atcatcaatc tccctattct ctacttccta
    11881 gtttagtcaa aaatgccgat gatattgata tccaagttat tttaaccgct tatcaattag
    11941 gtgacactgg aataatcaca cttatccatc aagccttact ctatcttagt caaaccattt
    12001 taaatatcag tatgatgatt gactctcaaa aaatctacct acatagtcct ttactaacaa
    12061 atcaacacat catccaaaaa ctatatagtg aaatgaacta caaacccaaa ctgctctata
    12121 atcgcctacc tgaagtcatt attgaacctt acaatgattt tacagccgca cactcagcta
    12181 ttgcactttg tttgtatcat acaattctac attcctaatt ttctattaca tttaataaat
    12241 aggctaaaaa gagggagtat atcataaaaa gcgaacaaac ctgttttctg aaaatcagaa
    12301 ttctgttttg ttcgctttct ttatatttgg aattatactc ctatctcccc tttttcataa
    12361 tgtatagtaa aatgaaataa taacaggacg aatcgatcgg gacagtcaaa tcgatttcta
    12421 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tatactatat tttcgtacag
    12481 gtgcttcaac catttgaacg atttcaaatc cttctttttg gtaaagattc tgagctcttt
    12541 gatttgcctc gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac
    12601 taacaaattt ccttaaagcc tggctaccta agccttgctc ctgtttctgg gggttgataa
    12661 aaaatctccc gatatgaaga ttgctgtctt ctagcctgat tttctggata aatcccacaa
    12721 actcttgttc atcaaagatt gaaaagactc cttccaaggc ttgaagggtc agtagaaaag
    12781 gaatccttgg tcccatccat tgttcttgaa aggatttgcc tagggagttg gaccactggc
    12841 atacaaattg agcgttttct atactcacct tttcttcaaa acgaattgtc atcttttcct
    12901 caccatctta tctatgtttc tccattatac tatttctccc attttttacg aatagataag
    12961 tatgattgat ttttattttt ttctcgtcgg gagcattctc gcttcctttc ttggtttggt
    13021 cattgaccgt tttccagagc aatccattat cagttcagcc agtcactgcg attcctgtca
    13081 gactcgcttg cgtcccttag atttgattcc gattctctca caggtcttca atcgctttcg
    13141 ctgtcgctac tgcaaagttc gctatcctgt ctggtatgcc ctctttgaat tagtcttagg
    13201 actcctcttt ctgctttact cttggaaatt gctttccttg gggcaagtcg tcctaatcac
    13261 cgctggtttg accttgggta tctacgactt tcaccatcag gaatatccct tactggtctg
    13321 gatgacttgc cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt
    13381 cctcatactt ggaattttgg ctcattttat cgatatccgc atgggtgcag gggatttcct
    13441 ttttttagct tcttgtgctc tcgtctttag cgtaacggag ttactgatct tgattcagtt
    13501 cgcttctgcg acgggtatcc tggcctttct cctgcaaaag aaaaaggaaa gacttccttt
    13561 cgtgcctttc ctcttacttg ctacttgttt gattattttt ggtaagctac tgcttgtcta
    13621 ataaaatcca atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat
    13681 tatttctttt gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat
    13741 actgatcaaa aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac
    13801 tttgtttaga cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa
    13861 tactctttac tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt
    13921 tgtaaccttt ttgcgcaatt tgacgataaa agtaagaatg ttgctttgga gtcaataatc
    13981 ctaacttaaa agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata
    14041 aaatataact atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa
    14101 actcttcttt tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat
    14161 cgccatcttc attcatatct ttatatttat gtaaaagaat atgtcctagc tcatgagcta
    14221 agtcaaaatt tcgacgtaca gatgatttat tcgttcccaa cacaatataa ggtcttccca
    14281 attttgacca tgcgctataa gcatcagctt ggccattaat taatcgttcc acgatataga
    14341 tgcctgaacg ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt
    14401 ccctggcata aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta
    14461 cattacttag gtcatgaatt gtaatattag gtataattac aaaactttca aaataatcaa
    14521 tcaaactatc taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta
    14581 ggtctgcatt tctaaaggca attacagaag aatcaaatcg aatgctctct tcttcctgtt
    14641 caaaataagt taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag
    14701 gtttcgtttc gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag
    14761 ctaattctgc tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa
    14821 acatttacat actccttact acttttgacc ttcttgtttt tctattcttg gaataatttc
    14881 aaaatcttct gtttccgata attctgaaaa attaggaata tcttggtatt tagcttcttc
    14941 gaaatggtac gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc
    15001 agttcgtgca tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc
    15061 ataagttaaa atcataaatt tttcgatatt cgaatttttg gtagcttgtt caatttcttg
    15121 aatcatttca tcagaaacta actccatctg aattggaaag gaatgactat cttcatcatt
    15181 tttgtaggaa gaatgttgat taagataaag tgtattcatt tgagcatatt caaataagta
    15241 gccactctta tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat
    15301 aattaacaat actttcccat atttttctgt atttgtttca aattctaaat atccccaagt
    15361 ctgtcctgct aattgtaatt tatactcaaa caaatctgct gatgcaaatg cagtatcaat
    15421 atgattaggt cgcgtccatg cataaccatt cgacactatc attgtctctc ttttttctag
    15481 acgttcatct acataatctt tttgcccttt catcaaagta tctacaattt tttgtgcctc
    15541 aagcgaatca aagagatcct gattcaacat aattcttcct cctccaaata ctttttaatg
    15601 aattatatca ttttcttaaa gaaattacta caataattag ctttttctta aagttctgtg
    15661 tcagagtaat ttagaaaatt atatcttcta tagtaaaatc aattaaaaac tgaacaaatt
    15721 tattgggaaa ttcaaatcac tttcttaaaa tattttagga accgtagtgt aatattccag
    15781 attcaattca ctataaaact agcctttctc ctgcaaaaga aaaaggaaag acttcctttc
    15841 gtgcctttcc tcttacttgc tacttgttta attatttttg gtaagctact gcttgtttga
    15901 taaagtcctg aatcggctct ccttggtgga gagcttttac tattttcgaa ccgacgataa
    15961 caccatctga caccgcattg aagcgttcca gatcggcttg actagataca ccaaaacctg
    16021 tcaagactgg gatgtcggcc acttgatgaa gttgcgccaa gtgcttgtcc aaatctgcac
    16081 ggtaattgcc tgatttccct gttaccccat tgatggcaac ggcatagacg aatccctccg
    16141 ccccttcaat caactctttc tggcgctcaa ttcctgtggt caagcttact aaaggaatca
    16201 aggcgatatc tgtatctgcc aaaaatggtt ctacaaagtt ggcatgttca tgaggcaggt
    16261 ctgggataat caagcccttc acagctgtat cagccagatc tttgacaaag ttctccacac
    16321 cgtactgaaa gagggggttg aagtaggtca tgatgaccag tggaatctct gtttcaatgg
    16381 ttttcaaggt ttcaactaaa gcctgggtag aggtcccgtg ggctaaactg cgcaagccag
    16441 cttcttcgat aacaggtcca tctgcaacag ggtctgaaaa gggaataccc acttcaattg
    16501 cagagacacc caaatcttct aaaaagtgaa ttgtttcagc aagaccatcc aaaccttttt
    16561 cgtggtcacc agccatgata tagggaacaa aaattccttt tccagctgct ttaatagcat
    16621 ttaatttttt tgttagtgtc ttaggcatga gcttctccct tctttgctgc atctgcttcc
    16681 aagcggtctt ttacttgaac cacatccttg tccccacgac ctgataggca tacaatcata
    16741 gacttttctg gtccaagttc tttggccaat ttcaccgcaa aggcgatagc atggctagat
    16801 tccaaagctg ggataatccc ttccacacga gacaagagtt ggaatccttc caaggcttct
    16861 tcgtctgtca cagggacata gctggcacgt ttaatatcgt ggtagtgaga atgctctgga
    16921 ccgataccag gatagtccaa acctgctgag atagagaagg cttcaagaat ttgaccatgg
    16981 gcatcttgga gcacatccat gagggaaccg tgaaggacac ctggacgacc cttggtcaag
    17041 gtagctgcgt ggtgctccgt atccacacca aatccagccg cttcagctcc atacatggct
    17101 actgactcat cttctacaaa gggatggaag agaccgatgg cattcgaccc accaccaaca
    17161 caggctacta gggcatctgg cagattttgt cctgtcaagt cacggtactg ttgtttagcc
    17221 tctcgaccaa tgacactttg gaagtcacga acaatttctg gaaatggatg aggccccaag
    17281 gcagaaccaa ggatatagtg ggtatcatct atattagcca cccatgaacg aagggctgca
    17341 ttgaccgcat ccttgagcac gcgcgaacca tctgtcacgg cctcgacctt agctcccaaa
    17401 agctccatac ggaagacatt gagggcttgg cgtttgacat cttcctcacc catgtagatg
    17461 gtacattcca tgttaaagag ggccgcagca gttgcagttg ccacaccgtg ctgaccagca
    17521 ccagtttctg cgataatttt ctttttaccc atgcgtttgg caagccaaac ttgtcccaag
    17581 gcattgttaa tcttgtgggc tcctgtatgg ttaaggtctt cccgtttgag ataaatcttg
    17641 gctccgccga tatgctgggt caagtttttt gcgtaataaa gaggagtttc acgtcctacg
    17701 tactggcgca aaagctggtt taattcctct tggaaacttg ggtctgcctg actttcacgg
    17761 taggccttct ccaactccaa aactgctgtc atcaatgttt ctgggacaaa acgtccgccg
    17821 aattttccgt aaaatccatc tttatttggt tcctgatatg ccatgcttta ccctctctat
    17881 aaatcttcta atcttttcat gatctttttg tccatctgtc tccactccgc tcgatacatc
    17941 tactgcatag ggagtaaaat gttgaattgc ttttactaca ttatcttcat taaggccacc
    18001 tgcgataaag aagggctgtg ctagtccagt cgtatccagt tgaccccaat caaaggactg
    18061 accacttcct gccacagggg catcaaagag tagataatct gcctgagaat tggggacatg
    18121 cccatttcca tctacctgca cagcctgaat actggcacaa ggcaaattct caaataaatc
    18181 agctgccacc tgaccgtgaa cttgaaccaa gtccaagcca actttgtcaa tcgcttccag
    18241 cagttctacc cgacttggtg aaacaaatac tccaaccttt ttcacatctg caggaataag
    18301 ctttgccaac tcagctgcct cttctaaagt cacctgtctt ttactaggtg caaagacaaa
    18361 accgatatag tcggctcctg ctgaaacggc tgtttccacc gcttctttgg tcgatagtcc
    18421 acaaatttta acctttgtca atctgcaact ccttgattct ctgggccaca ttttctgcct
    18481 gcataagagc tgtccctacc aaaattccgt taaagtatgg ggctagtcgt tccgcatcct
    18541 gccctgtgaa aatggcagat tcagaaatgt aatagcgacc ttcctcaaag taaggggcta
    18601 aatctacact ggtctgcaag tcgacctcaa aggtagtcaa gttgcggttg ttgaccccga
    18661 taatctcagc accaagtctg tgggctacct ctagttccgc tagattgtga gtctccacta
    18721 agacttccag accaagctct gtcgcgtagt catacagttc cttgaggcgt tcttcggaca
    18781 aggctgccac aataagcaag ataactgtcg cacctgcatt gcgagcgcgg atgatttgct
    18841 tttcatctat gataaagtct ttgttgagcg tcggaatctc tacctgactg gaaatttccc
    18901 gtagataatt caaatgccct ttaaagaaaa cctcatctgt caacaccgaa atcatcactg
    18961 ctccgttttc ttcataagtc tgggcctgtt gcacaatatc cacatcgaga ttgatatctc
    19021 ccaaactagg gctagctttc ttgacctcag cgattacctg caagcggtcc tgatgattct
    19081 tcaaaaattc tgccaagcga taggtctggc gcagaggctg gatttgctcc agcttcattt
    19141 gctccacctc acgcgccttc tgctctaaga ttcgtgctaa aaattcctga ctcatttttg
    19201 atactcctgt aacagtctga gtttttcaag ggccttgcct ctagcaatca cttgacgggc
    19261 caaggcaact ccttccttga tgctatcaat cttaccatta gcatagaaac caagaccagc
    19321 attcaagact gtcgtttcca agaatggact tgcttcgttt ttcagaacgc taagcaaaat
    19381 ttctgcattt tcctgagcat tcccaccacg aacatcttcc atagcatagc cttccattcc
    19441 caaatcctct ggagtaaagc ttgacaagct gatttcgcca ttttcaagaa gtgcaatctt
    19501 ggttgttccg ttcaagccag cttcatccaa cccttctggt ccagcaacca cgatggcacg
    19561 tttgcgaccc atatttttca aaacctgagc tgtactttct aggagttctg gacgactaat
    19621 tccaagaagc tgtgtttcta aagccattgg atgaatcagt ggaccagtca agttcataat
    19681 cgttggaatt cccaattcca aacgagctgg catgatgtat ttcatagctg ggtgcatatt
    19741 tttagcgaag agaaagacga ttccagtttt atcaaagacc ttacctagtt cagctggttt
    19801 gaggtcaaga ttgattccca aggcttcgag gacatctgcg gaaccagatt tagaagaaat
    19861 cgagcggtta ccatgcttgg ccatgtgaat accgccacca gccaagacaa aggctgcagt
    19921 tgtggaaata ttaaaactga aagacttgtc cccacctgta ccacagttgt ccatggcatc
    19981 atgaatctca gttggaatat gctgggcatg tcctctcatg acttgggcaa tggctgtgcg
    20041 ttcttcaggt gtttccccct tcatcttaag agctaagagg agagaagcaa tctgcgcttc
    20101 agttacacgc ccagttacga tacgctcaat gacatccgtc atttccacac ctgataaatt
    20161 ttcaaatttt gctagttttt caataatctc tttcatccta gtttcctcac tttacaacct
    20221 tctcgataaa attccgaata gaagacaagc cgtctggcgt tccaatgctc tctggatggt
    20281 actggaagcc ataaatcggt aggtttttat gttgaatccc catgatggct tggtcatcag
    20341 tcgaacgagc tgtcacttca aagtcttctg gcatttcctc aatcaaaata ctgtgataac
    20401 gcatgaccgc acgtccatcc tcaatacctt gatacaaaac agatggcgct tcaaagttga
    20461 tattgctctg tttcccatgc atgacttttg gagccaaacc tagcttacca ccaaagactt
    20521 ctgcaatggc ttggtggccc aaacaaatcc ctagaatcgg cttcttgcct gcaaaatcac
    20581 gaatcatgtc ttccatcttt ccagcatcaa ctggccaacc aggaccagga gaaaagacca
    20641 gaccatctgc tttttcagct tcttcataca gcttggaatc atcatttctc agaacctgaa
    20701 cttctgcaaa attcccaatg tattgggcca agttataggt aaaagaatca tagttgtcaa
    20761 tcaataaaat catggtctta gttctccaat tctagtcata gattttgctt tgttaatggt
    20821 ttcttggtat tcgttttggg cgatagagtc gtagacaatc cctgccccag cctgcacata
    20881 ggctctttga tttttgagaa tcatggttcg gatggcaatg gccaaatcca tatcacccgt
    20941 cgcagacaag tagccgattg ctcctgcata tacgccccgt ttttccgttt ccagttcata
    21001 gatgcgtctc atcgcccgaa tctttggtgc tccagaaacg gttccagcag gaagcgttgc
    21061 tttcaaggca tccatggcag tgagttctgc aagcaaacgc cccttgacca cgctggtcaa
    21121 atgcatgacg tagcggaaga gctccacctt catatactta gtaacttgga cactggccgt
    21181 ttcagagatg cggccaatat cgttacgccc caagtctacc aacattcgat gttctgctgt
    21241 ttccttctca tcagagagga ggtcagtcgc caaggtcttg tcttcttcat ccgtaacccc
    21301 tcttggtcgc gtccctgcaa tcggattggt tgtcacgatg ccatttttga cagaaactaa
    21361 actttctgga ctagctccga tgatttgata atccccaaaa tcatagaaat agaggtaatt
    21421 ggatggattg gtcacgcgga gatttctgta gaagtcaaat gaatttccag taacttctgc
    21481 tgagaaacgc tggctgagta cacattggaa catatcacca ttacgaatca agtcacgagc
    21541 tgtttctacc attacctcaa acttatgtgg agcgatatgc ggtttgaagt caagtggtga
    21601 taaatccaag tcttcaaatt catttggagc aggaatgcgt aattcctcaa gcacttggtt
    21661 caaggatttt tccaaggcct cttgactgcg ctcactatag agagcatcct ctatgacatg
    21721 tatcttctcc ttcttgtggt caaagaccat atagctctca tagacaaaga aatgcatgtc
    21781 tggcgtccca attgtatcct cagggatttg accaatttct tcataaagcg aaatcatatc
    21841 gtaacccaca aaaccaatgg ctccaccacc aaaaggtagc tctgagtggt gctgactctt
    21901 atgaatcact tcataaagga aatccaaggg atctcgatca atcacttgac cattttgata
    21961 aagaactcca ttttcaaact taatctcaaa aacaggatta taggctaaga tagaaaaacg
    22021 agctgtttcc ttgtctctcg gaatactctc taagataacc ttgtgttgcc cctttaagcg
    22081 catataagcc aagattggtg ataagacatc tccatgaatg attcgttcca ttgtaatttc
    22141 cctttcagtt ctacttctag tccgtggtga ctgtatgaaa aatccccacg caaaataact
    22201 tgcgtgagga cgaaattcgc ggtgccacct caattatagg atttctccta tctctcattc
    22261 ctgtctcaga tacctcctgt aacaggctgt gcgataaagg gcactccctt gagaatgatg
    22321 ttttcttctc tcgtttcaga tgaacccaac tttacagctt tctctgcttg ttttcagcaa
    22381 ccacaagctc tctgtgagag aaaagactgt aatttttcca tctattattt tttagcttct
    22441 aggtaatctg caatcgcagc taggtccttg cctccacgac cagagatatt gatgaggaga
    22501 tttttatttc gatacacctt tatactcttc gaaaatctct tcaaaccgcg tcaacgtcgc
    22561 cttgccgtag gtatggttac tgacttcgtc agttctatct gcaacctcaa aacagtgttt
    22621 tgagctgact tcgtcagttc tatccacaac ctcaaaacag tattttgagc tgacttcgtc
    22681 agttctatcc acaacctcaa aacagtgttt tgagcaacct gcggctagtt tcctagtttg
    22741 ctctttgatt ttcattgagt attactagct tttttcgtat tagtccagct ttttgtttgc
    22801 ttttagtagt aggcaaggag ctgtagatag aactcaagtt catcaaagcg acttaaggcc
    22861 ctaataaaag ataaaccaaa cgacggatag aaaaaagccc acacacaaaa tatacttccg
    22921 tgtgagggcg ttggtaacgc ggtgccacct caattataaa gggactatcc ctttacatct
    22981 ctgccttgtt taacaacaag ctgcactgta aggtgtgcgc accgaatttt cattgtttca
    23041 aattcatttt caaaatcagc ccactttcac tacttccaac cacctattca caaccaccac
    23101 aggctccctg aagatcaaaa atagttactt ttctgatttg ttgaacttat tttaatactt
    23161 tgttttttct ttgtcaagac ttttttacga tttttttgaa aatatcattc gaatgtgacc
    23221 atgtcttcct tagatcgaac atgaacatgt cccacttgtt agaaattgga tccaactcaa
    23281 tagaaactga atggaggcta aacagaactt attttagaac actccatctt ttccactagg
    23341 attttcaaga attaaacaat actagaaact ctgtctccta acaaatttag gagaaacttc
    23401 aacagatgtg acactttccc ctttaataat tgctaaaaca ccttctatca tttctttagc
    23461 caatttaaca taattgggag caattgtaga caaagctgga gtataatact gagaaatagg
    23521 aatattatca aatccaatga tagaaatatc atctggaata agaattcctt tctcatagca
    23581 cgcacgaatc aagccctgaa ccttttcatc tcctgaaaca aaaataatgt ccggataatt
    23641 ttgggtagtc aagtgctgca ttgcataaga ataaactgaa tcaattgtag ataagccata
    23701 aatgactttt aaatccataa agtaattttt atcattcaga aaagaacgca cacctctttc
    23761 acgatcctta ttaacatggg attctcctcc cataagcaac cacatatttt taaatttttc
    23821 ttcagttaca gctttcatca tatcataagt agcttgaaaa ttattattag atacatagac
    23881 tactccagac gtttgagatt caccgaaaac aagaaaaggc atatggttct tctttaaata
    23941 ctgaattctg atatcatcta cactttcata aaaaacaata acaccatcta ctaggctacc
    24001 tgtgcttgat ataattgaat tactaattgt atcctcctct ccaaagtact caactatagc
    24061 attaacacca aattctttac acgtccgtaa cactttatct aacagcgtat gaaaccaaat
    24121 taaaggaaaa gagtcgattt tttttacaga aatcaatata tttatagctt cttttttagt
    24181 taaatttttt gcatacgcat ttggaatata cgacaattcc tctataactt tttgaatcgc
    24241 ttgataagtt tcttctttaa catttactcc accattaata actcgtgaaa ctgtttttgg
    24301 agaaaaacct gataaacgtg caatatcata aatagttacc tttttcccat ttatattttt
    24361 catttcagtc ctccattacg
//
LOCUS       DAVLAQ010000027        24193 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000027 DAVLAQ010000000
VERSION     DAVLAQ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.027"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(99..248)
                     /locus_tag="VXB71_001183"
                     /pseudo
     CDS             complement(99..248)
                     /locus_tag="VXB71_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(402..2033)
                     /gene="rlmD"
                     /locus_tag="VXB71_001184"
     CDS             complement(402..2033)
                     /gene="rlmD"
                     /locus_tag="VXB71_001184"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0451303.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2107..3081)
                     /locus_tag="VXB71_001185"
     CDS             complement(2107..3081)
                     /locus_tag="VXB71_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0451304.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3155..3769)
                     /gene="pmp23"
                     /locus_tag="VXB71_001186"
     CDS             complement(3155..3769)
                     /gene="pmp23"
                     /locus_tag="VXB71_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0451305.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(3769..4743)
                     /locus_tag="VXB71_001187"
     CDS             complement(3769..4743)
                     /locus_tag="VXB71_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0451306.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4751..6007)
                     /locus_tag="VXB71_001188"
     CDS             complement(4751..6007)
                     /locus_tag="VXB71_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0451307.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(6069..6500)
                     /locus_tag="VXB71_001189"
     CDS             complement(6069..6500)
                     /locus_tag="VXB71_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451308.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6502..7104)
                     /locus_tag="VXB71_001190"
     CDS             complement(6502..7104)
                     /locus_tag="VXB71_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0451309.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7088..7927)
                     /gene="prmC"
                     /locus_tag="VXB71_001191"
     CDS             complement(7088..7927)
                     /gene="prmC"
                     /locus_tag="VXB71_001191"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0451310.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(7927..9006)
                     /gene="prfA"
                     /locus_tag="VXB71_001192"
     CDS             complement(7927..9006)
                     /gene="prfA"
                     /locus_tag="VXB71_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0451311.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9003..9593)
                     /locus_tag="VXB71_001193"
     CDS             complement(9003..9593)
                     /locus_tag="VXB71_001193"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0451312.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9716..9898
                     /locus_tag="VXB71_001194"
     CDS             9716..9898
                     /locus_tag="VXB71_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0451313.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10034..11407
                     /gene="mnmE"
                     /locus_tag="VXB71_001195"
     CDS             10034..11407
                     /gene="mnmE"
                     /locus_tag="VXB71_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0451314.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11454..12389)
                     /gene="dapA"
                     /locus_tag="VXB71_001196"
     CDS             complement(11454..12389)
                     /gene="dapA"
                     /locus_tag="VXB71_001196"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0451315.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12445..13521)
                     /locus_tag="VXB71_001197"
     CDS             complement(12445..13521)
                     /locus_tag="VXB71_001197"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0451316.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14152..14224)
                     /locus_tag="VXB71_001198"
     tRNA            complement(14152..14224)
                     /locus_tag="VXB71_001198"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14189..14191),aa:Thr,seq:ggt)
     gene            complement(14324..14833)
                     /locus_tag="VXB71_001199"
     CDS             complement(14324..14833)
                     /locus_tag="VXB71_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0451317.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14831..14927)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14956..15387
                     /locus_tag="VXB71_001200"
     CDS             14956..15387
                     /locus_tag="VXB71_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0451318.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15469..15846
                     /gene="mscL"
                     /locus_tag="VXB71_001201"
     CDS             15469..15846
                     /gene="mscL"
                     /locus_tag="VXB71_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0451319.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15888..16982)
                     /gene="hemH"
                     /locus_tag="VXB71_001202"
     CDS             complement(15888..16982)
                     /gene="hemH"
                     /locus_tag="VXB71_001202"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0451320.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVAFVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17137..18360
                     /gene="pepT"
                     /locus_tag="VXB71_001203"
     CDS             17137..18360
                     /gene="pepT"
                     /locus_tag="VXB71_001203"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0451321.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18396..19025)
                     /locus_tag="VXB71_001204"
     CDS             complement(18396..19025)
                     /locus_tag="VXB71_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451322.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            18990..19211
                     /locus_tag="VXB71_001205"
     CDS             18990..19211
                     /locus_tag="VXB71_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451323.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19482..20493)
                     /locus_tag="VXB71_001206"
                     /pseudo
     CDS             complement(19482..20493)
                     /locus_tag="VXB71_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20719..23838)
                     /gene="phtE"
                     /locus_tag="VXB71_001207"
     CDS             complement(20719..23838)
                     /gene="phtE"
                     /locus_tag="VXB71_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0451324.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         6927 a         5016 c         4453 g         7797 t
ORIGIN      
        1 caactattta ttttttgagt tttaaacttt ggtagaagtc ttgaactcct tatatttaca
       61 taactatttg cctctataac tgttatgaca cgaaaccaac aagcaagttc aagcacctcc
      121 atatctttat tcaaatgagg actaagatat tcacaaactt tatcataaac ctctttatct
      181 tttttcataa aaggggcata caacttagca aatttatcct aaaatttttt gttgccttta
      241 tcaatcattt caacgctcct ttaaatataa aaatgatcct atcaatcttt atattgagcc
      301 tattttctaa ttgatacctt gcaagaaagg aataatagct gttcctatac caagtaggaa
      361 tgtaataaat gcagaaagtc atatactgtc attcttttct attaaatcat tttgaagtgt
      421 ctcaaagcat ccatgatggc ttcttctttt tcaggtgtac actgtggaat aatttgttta
      481 tcctttttag acttgttgta atgttctcgt aattctattc cacatttctt ttttatctgt
      541 gcaatatata atgtcgaaac ttttaattca aatttattcc aaacatattc tttgatttga
      601 gcatatgttg ctttgctctc cgcacttgtc aaatccatct catccagctc aatttcaaca
      661 cttatgtgct tatcgacatc gagtttggac aaaagtgcta ccgtctcgac gtgatgcgtt
      721 tgaggaaata gatccaccgg ctggactttc ttcaattcat atcccaactc ttggtatagt
      781 ttaatatcac gcgccatggt tgcgacattg caggagatat aggcgatgcg atcggctcct
      841 gtttgggcgc ttgctttgat aaagctttct gtcaagccct tgcgtggagg atcaaccaag
      901 ataacggttg gttgaatacc ttccttgagc catttcttca tggcattttc agccgtgtca
      961 cagacatagt gggcattagt aatcttgttc aaagaagcat tcttctggct attctctact
     1021 gcttctggaa tcagttcaac accgtagact tctttgacat gcttggcgac tgataaacca
     1081 atggttccaa taccagaata ggcatcaata atcacatcat ctttttttaa ctctgcaaag
     1141 tcaatggctg tttgatagag tttctccgcc atttcagtat tgacttggta aaaggctggg
     1201 ccagcgattt ggaagtcatt tcccaacatc tggtccgtaa tatagtcttg accataaaga
     1261 gtgcgccact ccttaccaaa aatcgcattg gtattctggt cgttgatatt ttgcatgaca
     1321 gacacaatct ctgggaactg cttgataact tgttcaatca attggtcaac acgaaaaact
     1381 tttggacgag ttgtcaccaa aacgaccatg atttgtcctg aatagtgacc acgacgcacc
     1441 acaagattcc gaatcaatcc agattgttcc ttttcgtcat aaggttttaa atcaaaacga
     1501 cggagcaggt ctcgaagagc tactacgact tggtcaatga caggatcctg gataaagaaa
     1561 tcttcaaggg gcatgaggtt atgcgaattc ttacggaaaa atcctgtttc caagacacca
     1621 ttcactcgac gaacgggcac ctgcgcctta ttgcgatact tgactggatg ttccatatca
     1681 agcgtttcag caacttctac atctgcaatt ccagcaatct tgtagagact gtccttgact
     1741 tgcttggttt taaacttgag ctgttctgga taagaaaggt gtcctaaatc cgcgattcct
     1801 gaacgcaggt aagccaaatc tagatcttga ttacggtgtg gtgactggac aaggtatttt
     1861 tcaacttttc caaagccaat ctttttattg accttgagga cacgcatgag aattttttca
     1921 ctcggtaaag cattctctac aaaaaagacc aaaccatcta ccttggcaac tcctgcccct
     1981 tcatgggtca aatcaacaat ttcaacttct acaatatcat ttttctttaa cattcttttc
     2041 tctttctatt ggccgacaaa aaagacggca acgttacggt taccatccat tataccatga
     2101 aatttcttaa gaaccaaaac tcttgaagaa gttgacaagg gcttgccaga gggagcttaa
     2161 gaagttacca ccgtcctcta gcgccttatc cgcatcaaag ttaaggttga tatttttaaa
     2221 actgtcgcca gcttgtgata cgatgctttg tttaaggtca tttagggttt tagtgaaatc
     2281 tgcattgctg aggatatcac tctttgagag attcaaggca aaattgatga tgatattgat
     2341 ctggtttcct gttatgacct gatcaagttt gtaatttttt aaggtatctt caacaatctt
     2401 gcgtacatct tcttctgtca gatttccctt gctttcttta gctttggcga gtcctgactt
     2461 gatatcagct agggcaacgt ttaatttatt agcatcatag cctgatttgt ccttgttttc
     2521 agcattgata tctgacaaag cctttagctc ttcttgagcc aaatctttat tggcttgcgg
     2581 caccttggct ccattagctt ctagcgaata gtagatccca gccaaagcac tctcacctgt
     2641 aactggaata ggggctgcta cagtgatttt ggcatgttcc atacccagcg ttactgctgc
     2701 gtttcggtac atatcctgag tcaccttagt gatattttct ggtgtttcaa tcttgacctc
     2761 aagtggcgat ttgtcaccta gcttttgaat cttggctgat gaatacaact gtaagctaga
     2821 gtcattggcc acattcatga ttttagaata aacatcaggt gtcatggtct tgagttcttt
     2881 ggtatctgtt gaggcattgt agcccagttt tttaagagtt tgattttttt ggtcttcaga
     2941 tagggaggaa cctaggacat attcaggttg gacataggtt tcatcgataa ctttttgaac
     3001 atctgttgct gcatggacgc tattcatagc tgttactgcc cacaagaccg cagcactagt
     3061 cagaaagagt ttctttctca tagggaattt cctcctttac ctttctagag taatatatct
     3121 atcttaaaga aaacttataa caaaaacacc tgaactagcc agatgttgaa aagagagtga
     3181 aacatttgat gatgtaaagg ttgagttgca cctgtctaga ataataatag tttcctccat
     3241 ttacatagag ttcggcaccg tgaaaaatgg aaatgggatg aatataacta taagtctttc
     3301 cagtcgtatt accaagcaag ggggcaacag tctcacgaga gtactgtttg gctagagcca
     3361 aggtattttc cttgccattt tgggcgataa aatcgatata ggcaggtcca aaattatagg
     3421 cttgaacagc tgtccagata tctacaccct tcttctgcgc cagatagaga ttgcctgtca
     3481 gagtttgaat gccttgccga atgctagagg cattatcatt gatggtgttg gtggaaccac
     3541 ttgcagactc actagactgc ataacatcgc cttcttttcc ttttgtttca gtataaatca
     3601 tagcaagcac aagctcttcg tttgctgggg tgtctttttc actcaatatt tctcgcacca
     3661 tgggttgata ggtcatgact tgtttgacat cttgatgaac gcggtaagct ttatagccag
     3721 caaaaaggaa gactgctagt acaagcactc ttcgaattcg tttaaacatt atttactttg
     3781 gatatcctcg atatttttga ttaagataga gtaggttcca ttttcgtttt ggataaactc
     3841 aacagactcg gcgtcttgat agacgttatt gggaacgatg agctcaattc catttgataa
     3901 ggagagtttt tggttttcaa atttctttaa ttggcgactg acatcaattt catcaaattg
     3961 aacaggttct ggtacggctt ctttgacttg gtcaataaag ctcaaacgag ccgtcagatt
     4021 gttgtcaaaa aggtcattag ccaatttctc aggtgacaat tcattgcttt cttctaggtt
     4081 gttgaaaata gctgatttga ccttggattg aaattgaaaa tcatctgtgt taaaagattc
     4141 agcaattctc tgggctgttt tttccagttc cttgatagat tttttaggag aaatcttagg
     4201 agcgacagca agaagattat ctgaaaaata gttcaaaaaa gtcccgttgt acttgattcg
     4261 tttttcaatc aggtgatact tgctactctg aagattgacc accaaggcct catcagctcc
     4321 tgttccaaat ccaggcaggt tattctgagt tagcttgatt ggattatcaa cttctcctcc
     4381 gaggtgggtc aaggtctccc gcagggcaat tcgcaagaaa gcgaaatgtt ctacaccttc
     4441 tttagaaaat tgaacaaaaa tcaagtcatt ggtcttgaga ttttcagaaa tgctaaactc
     4501 ctctttccag agattagcca gcgttactga tgtctccaac aaatcgtctg taatatgatt
     4561 gaagaaggga ttttcttctt cgaaaatccc agtcttggct tcatctgaat acacatgttc
     4621 aattttttta cgcaggtatt cttcgatttt tggagtaata ttgagaaact tatctgctaa
     4681 gaacagttcg gtatcatccg gactgaactg gtgaataatg gctttcttaa tataaatgtc
     4741 cataaaagtt ttagtcctcg tatagtagga aggcatctgt caattctttg actgcacttc
     4801 tcacttcttc taatacagcc tcattttctg aattcttaag ggttttaatg atgagttcag
     4861 ccactttgcg actttcttct tcaccaaatc cacgtgcagt aatggctgct gctccgatac
     4921 gaatcccact tgtcttgaat ggtgacaagc tttcgtaagg gattgagttt ttatttaagg
     4981 taatattgac ttcatccaac aagttttgag caactttgcc gttttctaca actttagtca
     5041 catcaacaag gaagagatgg ttttcagttc cacctgaaat aatacggaaa tcagggtctt
     5101 gcaagaagac atctgccata gccttgctgt tcttaattac attggcagca tattccttga
     5161 aggctggatc caaaacttct ttgaaggaaa ctgccttagc cgccacaaca tgctctaaag
     5221 gaccgccctg aatacctggg aaaatagctg aattgatttt tttagcaagt tcttcgtcat
     5281 tggtcaaaat caaaccacca cgaggtccac gaagggtttt gtgggtcgtt gttgttgtga
     5341 tatgagcgta tggaactggg cttggatgaa ggccagccgc aaccaaacca gcgatatggg
     5401 ccatgtccac catgagcttc gcaccgacag catctgcgat ttcacggaat tttgaaaaat
     5461 cgataatttg agaatatgct gaagcaccag ctacaatcag ttttggtttt acttcttggg
     5521 cttgtttcaa gatagcatca aagtctaaga gttccgtttc aggatcaaca ctataagaaa
     5581 caaagttgta ggtttgacca gagaagctaa caggagcccc atgagtcaaa tgaccacctg
     5641 atgccaaatc cattcccata accgtatcac ctggctcaat caaggacatg taagccgcac
     5701 agttagcttg gcttcctgaa tgtggttgga cattggcaaa tttagcaccg aaaatttctt
     5761 ttgcgcgttc aatagcaaga gtctctacaa cgtctactac atcagttcca ccataataac
     5821 ggcgtcctgg gtaaccctcg gcatatttat ttgtcaagat agacccttga gctgccataa
     5881 cagccttgga aactacgttt tccgaagcaa ttaactcgat attattttgt tggcgttctt
     5941 cttctttggc aatagcattc cagagatcag catcatatgc tttaaaatca tctttgtcaa
     6001 aaatcatagg tcttctcctt tattgtgtga ctagtccatt agtttgattt tacaataaga
     6061 aaatcaaact aaaagatgcg aataaaccgt ttctgcattt tatcacaagt atagccaact
     6121 ttttcataaa atgcatgagc acccagacga tgattggcag aatttaagcg gataaaccca
     6181 taaccacatc tttttgcttc ttcttccaac ccttgtagta aacttttacc aataccttga
     6241 ccttgcgctt gaggtgaaac tgctaaagct aagatattaa atcctgcttt ggaatagagt
     6301 gattcgtaaa cttcagcgtg gacatatcca agtaagacat gattagctgc atcctcatag
     6361 ccaagtagga aatgatggga atcctgagac agtctagcta gttggctagc cgtttcctct
     6421 ggactaaaag tataacccaa agcctcttgg ttgatgtcac atatcgcttt cacatctgtt
     6481 tcttgcaaat ctcttagcat ttcaagcctc ctcaaaagaa atctctggca accgagcaag
     6541 aatatcttct cgtttaattg cgccttggcg taagattttc accttgtctc cagacaaatc
     6601 cacaatagtt gaatcctgtc cagttagaaa agcatcgtct tccagaccca gaacctcttg
     6661 gtcaaaatcc ttcagaattt gttcaaaggt tacaccactt gcctgacctg agatattggc
     6721 agacggccca atcaagggac ctgtctctcg aattaaatcc agtgtgatag ggtgactggg
     6781 catccgaaat ccaatagttg caaggtcaga atttacccaa tagggaactc ggtcattggc
     6841 ttcgagaata atggtcaagg gacctggcaa aaaggtctct acaagttttt gtagataagt
     6901 tggctgattc ttagaaaagt gcaagatatc ctcgaaagag gcgatattga gattgagtgc
     6961 cttatctcta ggacgacgtt tgagttggta aacatggtca actgcttttt catctaaggc
     7021 cttggcaaaa agaccataaa cagtctctgt aggtagaacg acagctccac cattttccaa
     7081 ctcttgtcta atcctgtcca tcatcaacca caaccatcct attttgacca aattggtctt
     7141 tgagtgttcg aacttttttt tcaggaagat gttttctaaa aagttcggga acactttgac
     7201 cttgcttgta tccaatttca aggtaaatct taccaccatc cttgagatag tcttttgcat
     7261 cttccgcaat tctacagtaa atagctaggc catcctcgtc tgcaaagaga gctagatgag
     7321 gctccgaatg caaaacattc aaacctacct ctgactcatc ttcacgagag atatagggtg
     7381 gattggatac aattatatca tatttttcag aaatttctgc aaaacaatca gattttttaa
     7441 aaaatatatt aagattttga tcgctagcat tctctgatgc aagctctaag gcctcttgag
     7501 aaacatctgc tgctgtcact gaccaatctg gtctattttt tgctagagcg agagcaatag
     7561 ctccactacc tgttccaata tccagaactg agagattcgt ctcaagattt tcagttagaa
     7621 taagctccac taactcctct gtttctggac gaggaatcaa aacccgttca tccaccttta
     7681 aatgcattcc ataaaaatct gcctgtccaa tgatgtactg agctggcttg tgagctgcta
     7741 gttgctggta aatatcttct acaaattgtt tttcttcctc tgttgtcacc tcctgctgga
     7801 gggcaaaaat aaagtctgta aaagatagat ttttcagact acgatagaca aaagagaggc
     7861 tttccgcttc ctctccttgt cttatcaact cttcttcaaa atttgaaaat aattgagcta
     7921 atttcattat ttgtttaatt cttctagttt ttgtgtttgg tcataaagca ccaaggcatc
     7981 cacaacttcg tccaatttac cagacaaaat cgtatctagt ttttggaggg tcaagccgat
     8041 acggtggtct gtgacacggt tttgtgggaa gttataagtt cggatccgtt ctgaacggtc
     8101 accagtaccg attgtcgact tacgctcagc gtcttgttca tcctgagcaa tctgagcaaa
     8161 gtggtcagcg acgcgtgcac ggataatctt catagccttc tcgcggttct tctgctgggt
     8221 acgttcttcc tgcatctcaa ccttgatatt ggttggcaag tgaacgatac gaacggcagt
     8281 cgcaacctta ttgacgttct gtccaccagc accagaggcg tgatagatgt cgacacgaag
     8341 gtcttttgga tcaatgtcgt attcaacctc ttcaacttct ggcataacaa gaactgtcgc
     8401 tgtcgaagta tgaacacggc cttggctttc tgtcacagga acacgttgca cacggtgggc
     8461 acctgattca tacttaagct tagagtatac agactgacct gaaaccatag caaccacttc
     8521 tttaaaacca ccgacaccat tcatagaggc ttccatgact tcaaagcgcc aaccttgggc
     8581 ttccgcatac ttttggtaca tagttagcaa atctccagcg aaaagtgccg cttcgtctcc
     8641 accagctgct ccacggattt caaggatgat attcttgtca tcgtttggat cctttggaag
     8701 gagcaaaatt ttcagttttt cttcatattc ttctttttca gccttggcat ctttgagttc
     8761 ttgcttggcc atttcttcca agtccgcatc tccgcctgat tccttaatca tctcttcggc
     8821 atcgacgata ttttgaagga cttgtttata ctcacggtag gctattacgg tgtcacgatt
     8881 ggaagcttct tcttttgaaa gctccataaa acgcttggtg tctgaaacga catcagggtc
     8941 actcagcaat tctcctagtt cttcataacg gtcttctaca gcttgtagtt gatcatagat
     9001 gttcattttt cttcattctc cttattgatt tcaggggcaa aataatgttt acggcaaacc
     9061 gagatatagg tttcattacc accaatctgg atctgttctc catcgtaaac gggcagtcca
     9121 tcctgtgttc gcaacaccat ggtcgccttt ttcttgcaat actgacagat ggtcttgatt
     9181 tcgtcaatct tgtctgctaa aagcaagaga tatttggaac cttcgaacaa ttcattgcga
     9241 aagtcatttt tcaagccaaa agccatgacg ggtatgtcta actcgtccac aacacgagct
     9301 aggtcataaa catggtggcg tttgagaaac tgggcttcat cgaccaaaac acagtaaggt
     9361 ttttctggta ggtctcggat atagccaaag atatccgttg tttcctcaat cgcaagggca
     9421 gggcgtttca tgccaattcg actcgacaca tagccaacac cgtcacgcgt atccagagcc
     9481 gaggtcataa tcacaacacc ttttccttgc tcctcgtagt tataggccac tttgagaatc
     9541 tcaatcgttt taccagagtt catggtccca taacgatagt acaactgtgc catgtttctt
     9601 gcttcacgtc catttctaaa tttttgctac attctagtat atcataattt tcttaagctt
     9661 taaacggcaa aatgtggtaa aatggaagaa atcaaaacta gtggaggaag ctattatgcc
     9721 atttgtacgc atcgatttat ttgaaggacg cacgctcgag caaaagaaag ctcttgctaa
     9781 ggaagtaacg gaagcggttg ttcgcaacac tggagcacct caatctgctg ttcatgtcat
     9841 catcaacgac atgccagaag gaacttattt cccacaaggg gaaatgcgca ccaaataagc
     9901 tagcttaagc agaattgctt aggctttttc aatctccaag tagcacccat tgaagaaata
     9961 gtctaaattt gttacaattt gaaaagagac ttggaaaatt ccaagaaaag agcaattaat
    10021 taaaggaaac attatgatta cacgtgaatt tgataccatc gctgctatct ctactccact
    10081 aggtgaaggg gctattggta ttgtccgcct gagcggaaca gacagttttg ctattgtgca
    10141 aaagattttt aaaggaaaag acttgaacaa ggttgccagc cacactctca actacggtca
    10201 cattattgat cctctgactg gtaaagtcat ggacgaggtt atggttgggg ctatgaagtc
    10261 tccaaagacc ttcactcgtg aggatattat cgagattaac acccacggtg ggattgcggt
    10321 gaccaatgaa attctccagc tagctattcg tgaaggggct cggttggcag aacctggtga
    10381 atttaccaaa cgtgcttttt taaacggtcg cgtagacttg acacaggcag aggctgtgat
    10441 ggatatcatc cgtgccaaga ctgacaaggc catgaacatt gcggtcaaac aattagacgg
    10501 ctccctttct gacctcatta acaatacccg tcaagaaatc ctcaatacac ttgcccaagt
    10561 tgaggtcaat atcgactatc ctgaatatga tgatgttgag gaagctacta ctgccgttgt
    10621 ccgtgagaag actatggagt ttgagcaatt gctaaccaat cttcttagaa cagcccgtcg
    10681 cggcaaaatc cttcgtgaag gaatttcaac agctatcatc ggacgtccca acgttgggaa
    10741 atccagcctt ctcaacaacc tcttgcgtga ggacaaggct atcgtaacag atatcgctgg
    10801 gacaacacga gatgtcatcg aagagtacgt caacatcaat ggtgtacctc tcaaattgat
    10861 tgatacagcc ggtattcgtg aaacagatga catagtggaa caaatcggtg ttgagcgttc
    10921 gaaaaaagcc ctcaaggaag ccgacttggt tctactagtg ctaaatgcca gtgaacaact
    10981 gactgcgcaa gacagacaac ttcttgaaat tagccaagat accaatcgca ttattctact
    11041 taataaaacc gacctgccag aaacgattga aacttcgaaa ctacctgaag acgttatccg
    11101 tatttcagtc cttaaaaacc aaaacatcga caagattgaa gagcgaatca acaacctctt
    11161 ctttgaaaat gctggcttgg tcgagcaaga tgctacttac ttgtcaaacg cccgtcacat
    11221 ttccctgatt gaaaaagcag ttgaaagcct acaagccgtt aatcaaggtc ttgagctggg
    11281 gatgccagtt gatttgcttc aagttgactt gactcgtact tgggaaatcc tcggagaaat
    11341 cactggggat gctgctccag atgaactcat cacccaactc tttagccaat tctgtttagg
    11401 aaaataagaa aaatccatga tccttcattc ggtcatggat tttattgtct ttattagtaa
    11461 tctggtctta agacccctgt tacagttgcc ttagttgctt cgtagtcgcc atctacgaca
    11521 accttgataa tgcgtttggc atcttcttct ggtgctggaa caagaggtag acgagtgggt
    11581 ccagcttcaa atcccatata gttaagaatt gccttaactg gagcaggact tggataagag
    11641 aagagagcat taaccttagg aatgaattta cgctgaattg ctgcggcttt cttcatatcg
    11701 ctttctgcaa tggcagtaaa catctcgtgc atttcatccc catttgtatg agaggcaaca
    11761 gaaataaccc catccgcccc aaggttcatg gcatggaaag catctccatc ctcacctgta
    11821 taaatcaaga actcttcagg cttgtgctca atcaagtaag ccatattagc caagctagta
    11881 cattctttga caccgataat atttggatgg tcagccaagc gaagcatggt ttctggagtc
    11941 aattcgacaa ctacacgccc tggaatgtta tagataataa ttggtaggtc agaagcatct
    12001 gcaatagcct taaagtgctg atacatccct tcttgagaag gtttgttgta gtaaggaaca
    12061 atagcaagcc cagctgcgaa accaccaaat tccgctactt ctttgacaaa ctcaatagag
    12121 tcacgcgtat cattagtacc tacacccgca atcaaaggaa cgcgtccatt gacaaccttt
    12181 tgtacagccg caaacaactc caactcctca tcgtgggtca aagttggact ctcagcagtc
    12241 gttcctgcga gaagaattcc atccgtatga tgggccaata aatgctcaat caaggctgga
    12301 atagcatcaa agttaatgga accatcctca tggaaggggg taataaaggc tgtaatgatt
    12361 ttacattctt ttaaatcttg ataagacacg aaaacacctc tctatttcaa agaaggagtt
    12421 catctgaact cctaaacgat atgactattt taattcaaat ttcaattcag ctgttggacg
    12481 aaccaatcca cgttcatgaa gagtttcagc aatctgaact gagttccaag cagcaccttt
    12541 gagaaggtta tctgaaacaa cccacatgtg aattcctttt tctgcatcca agtctttacg
    12601 gatacgacca acaaaggtat cacgtgaacc aactgcattg atggcttgag gatagatttg
    12661 atgaactaca tcatcttcaa gaacagcacc tgggaaggat gcgatagctg ctttgacttc
    12721 ttcaattgga gccacttcct ttgtttcaat ataaactgac tcagagtgag ctgacaagac
    12781 tggaatacgc acacatgtcg cagatactgc aatgctatca tcttccataa ttttcttagt
    12841 ttccttggtc atcttcatct cttcgtacgt gtaatcatta tcagtgaaga catcaatttg
    12901 tggaagagcg ttaaaggcga taggataatg tttcttgtca ccacctgaag gcaagatttc
    12961 cgcatgcaaa tcacgtggtt tcactccatc attcaagacc tcacgaagtt cacgttgtgt
    13021 ctcaagaatt gctcccatac cagcacctga aacggcttga taagttgaaa caatgatacg
    13081 gtccaagccc catttttggc gaaccggctc aagagccacc atcatttgga ttgttgaaca
    13141 gttagggcag gcaatgattc cgttgtgggc atcaagtgca tgagcattga cctctggaac
    13201 aaccaaagga acatctggat tttgacggaa ataagatgta ttatccacta ctaccacgcc
    13261 agcttttact gcgtatggtg catacttagc tgatgtcgaa ccacctgctg aaaagagagc
    13321 aatatcaact ccttcaaaag ctgtttcagt cgtttcttca atcgtaatat cttgatcttt
    13381 aaatttcaat gacttacctg ctgaacgtgc agaagcaagg taacggattt tatcgattgg
    13441 aagtgttgat tcttccaaca tttttatcat ctgagcaccg acagcacctg tcgcgccgac
    13501 tacagcaact gtatatccca taaataacct ctttcggaat tttctaaaaa tttctataat
    13561 agaagtatta tactactttt tccatgaatt gcaaagcttt ttcatcattt tttggaaaat
    13621 aaaaatcccc aatcgctaga ctagggatta agaggcatct tcatgtgatg agcaggttca
    13681 cacaactcat caaggtccgc tcctgcgtta tgacctcctt atgctcaata gtagcccgaa
    13741 gactacctat cgactcatcg catctactat tctactagat agagtcattt ttgtcaacag
    13801 ccaaaactct ttatactctt cgaaaatctc ttcaaacttc gtcagcgtcg ccttgccgta
    13861 tgtatggtta ctgacttcgt cagtttcatc tacaacctca aaaacatgtt ttgagctgac
    13921 ttcgtcagtt tcatctacaa cctcaaaaac atgttttaag ctgacttcgt cagttctatc
    13981 tacaacctca aagcagtgct ttgagcaacc tgcggctagt ttcctagttt actctttgat
    14041 tttcattgag tattagtttt atttacacag gtgcataaga aatatattgg aaaaattggg
    14101 ggcagacata acaaaaaccc ttgtaaatca agggcttttc tgtctattta atgctaattg
    14161 ccgggattga accggcgacc tcatccttac catggatgcg ctctgccaac tgagctaaat
    14221 cagcttactt aagaagtata ctatattcag aaaaacttgt caagtttcct tagaaatttt
    14281 ccataggaaa aagccaggta agaactacct agcttatctt cttctattta cttaaatcaa
    14341 ttcgacgacc aattttacca ataataatcg ctccaataat caatgaagca aattcaccga
    14401 ttcctgttgt aaaccaagta aggaagaatg gtaattctgc tacaatattt aactctgcag
    14461 cgatagtaaa catggaaatt gaaaagagga ttgaaaagaa gaaatgatct tttcgaatca
    14521 atccgttaaa gaggtaatcc ttgctatatt ttgcaaaaag ccaaacacct aaactgagga
    14581 atactaaggt tgaaccacca ccaacaaaga catctagcag tccgaagcta aagaaattag
    14641 caatcataca accgatggta actccgatga tgtacttagg attgtaaaaa gccataaagt
    14701 tcatcatttc tgaaatacga aactgataag caccatagct gatggcattt aggggcggtg
    14761 tgacagtcaa aacgacgtag atagcagcga cgattgcaat atctgcaaca tcacgaatag
    14821 ttaatttttt catcttttct cctttggcgg ttatccgcgt gtaatatgct tggtgaaaga
    14881 agctaagcac caagggttga ttcattcaac cttactagta tagcacaata gcctgcttta
    14941 tgctatactt aaagcatgaa aaaacctatt caaaaatttt ttaacaatga aatcttagcc
    15001 tatctctttt ttggccttgc gacaactcta gtttcgattc tctcacgact agtcatttat
    15061 caactaagtc atcaggaact ccttgctacg gccttggcaa atattatcgg tatcttattt
    15121 gcctttatca caaatgatac gattgtattt aagcaaaaaa agaaaaatag acttatccgt
    15181 ttagtgaaat tttctcttgc tcgcctttct acttttctgt tagacttgtt tttaactttt
    15241 ctctttgtaa cccaatttcc tcacatcata gggcaattcg taactgaaaa cattgataag
    15301 ataaatgcta ttgaaacaat aattgcacaa atattcatta ttatcatcaa ttatatcttg
    15361 agcaaggtct atatttttag aaaataatgc tccatttatg agccttttaa ttgccttcta
    15421 taatgattta ggatacaatg aaacacgaaa cattgaaagg aaaacagtat gttaaaaaat
    15481 ctaaaatcgt tcttgcttcg aggaaatgtt attgaccttg ctgtcggtgt tgtcattgcc
    15541 tctgcttttg gtgctatcgt tacttcactt gtaaacgaca ttatcactcc tcttatttta
    15601 aatcccgctt tgaaagctgc taaagtcgaa cgtatcgctc aactttcttg gcatggagtc
    15661 ggctatggta actttttaag tgctattatc aattttatct ttgtgggtac cgccctcttc
    15721 tttattatca agggcattga aaaagcacag aaactgactg gcataaagaa agaaaaaact
    15781 gccgaaaaaa aaccaaccga attggaagtc cttcaagaaa taaaagctct ccttgagaaa
    15841 aaataatcga ttaaaaggat ctagcgcaaa gctaaatcct tttttcttta ctctttgggt
    15901 aacttgcctg ctttttcaag catttttttg ataagataag gcatcttaac attctcccgc
    15961 ccttttttct caatcagttt tttcacaaat tctggcattt gtaaatcttc agattcagct
    16021 aaaatgtttt tcgtctcgtc tgaaggaact aactcatcaa aggtctcttc ttctgggaga
    16081 aattccttaa actcttgatt ttcattgact ctaactgtat tgaccaaagc atcaatcaaa
    16141 cgagaatctg tatttggcat tggtggacga tggtagttta ccccaaattc ctggcataag
    16201 tcataacatt ctacatcatt gtcaaacaag acctcaatat gctcactgat gaaactaata
    16261 ggtacaaaaa tataatggtc tggatgttct gtctgttctc tgagatactc caaaacatct
    16321 ggtttaatcc atggaatacc aatatcactc tcactctgcc aagtgttggt atattgttct
    16381 gaactcaagc ccagtttttc agcgactagc ttgctatttt cgaaaatttg gtctatataa
    16441 ggatcaccaa agtccaaggc aaaaatgggc acactatggg ctgaaaagat gactttaaag
    16501 ctgtcttgct ttacttcttc ttttaaaatc ttagcaattt catctgccca atagtttaag
    16561 agcgcttctt cctgatacca gtccttaatg accaaaaatt gaatttgttt gctttctaaa
    16621 aatttttcat agcccatgac agagtagaaa gaataatggg gctccaaaat caagcaaata
    16681 cactgttcaa ttccgtctgc ttccatttga ccgatcacat ctggaataaa gggactggaa
    16741 aacttattag caaagtagac actgtattca ttccccagcc tagcttctac aaaggcaacc
    16801 tcttgacggg taattttttg cagaggcgtg cctccaattc gtacataatt atcatagaga
    16861 gtctgaatct cgtggtcttg gggtctcacc ccacgacgaa tatttgtgaa aaaatcagct
    16921 acaccttcaa aggtaatctc ttctggtgaa ccgaaggtca tcattaaaat tgcttttttc
    16981 atgactgctt ccttgtgatg tttttatcaa gtttatttta tcattaatta atcgataagt
    17041 aaacgctaat atagggacat tctcaatctt ctgtcttttg tttttctctt ctttctatga
    17101 tacaatggaa aaaataaatt caaaaggagt ttttttatga cttatccaaa tctcttggac
    17161 cgcttcttaa cctacgttaa ggtcaacacg cgctctgatg aacactctac tactactcca
    17221 agtacacaga gtcaggttga cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt
    17281 ggactgcaaa atgtttacta tctaccgaat ggttttgcta ttggaacctt gccagccaac
    17341 gatccgtctt taacacgtaa gattggtttt atatcgcaca tggatactgc tgattttaat
    17401 gctgaaggag tcaatccaca ggtaattgaa aactacgatg gtggtgtgat tgaactaggg
    17461 aattctggtt tcaaactcga tccagctgac ttcaagagtc ttgaaaaata tccaggacaa
    17521 acgctcatca caacagatgg aacaagcttg ctaggtgctg atgacaagtc aggaattgct
    17581 gaaattatga cagccattga atatctaact gctcatcctg aaattaagca ctgtgagatt
    17641 cgtgttggtt ttggtccaga tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa
    17701 gattttgatg tggattttgc ctacactgtt gatggtggtc cactaggtga acttcagtac
    17761 gagactttct cagccgctgg tgctgaattg catttccaag gccgtaatgt ccaccctggt
    17821 actgccaaag agcagatggt caatgccctt cagctagcaa ttgattttca taatcaactt
    17881 ccagaaaatg accgacctga gttaactgaa ggttaccaag gtttttacca tctaatggat
    17941 gtgacaggta gtgttgagga ggtgcgtgca agctacatca ttcgtgattt tgaaaaagat
    18001 gcctttgaag cgcgtaaagc atccatgcaa tctatcgctg ataagatgaa tgcagaactt
    18061 gggagctacc gtgtcactct caacttgaca gaccagtact acaatatgaa agaagtcatt
    18121 gaaaaagata tgactccaat taccattgct aaagccgtta tggaagatct aggtatcacg
    18181 cctattatcg aaccaatccg gggtggaaca gacggctcta agatttcctt tatgggaatc
    18241 ccaactccga atatctttgc aggtggcgaa aatatgcacg gacgttttga atacgttagc
    18301 cttcagacta tggaacgtgc agttgatacc atcattggca tcgtagctta taaaggctaa
    18361 aaagacgagg tagctcagct acttcgcctt tctttttatt ctactggttt ttcttgattt
    18421 ccagtagttg tagaagattc tgttgtttca ttttctgaag ttgattcagc aggtttagaa
    18481 tctcttgtat tgcttggttt gttttcgtcg ctagcaattt caatgttaga ttctgcagtt
    18541 gcgtttggtt ggttctcagc actggtgtta tcactatttg cttcagcatt tcttgctgga
    18601 cttgtttctt cacttgcgct agcttttgac tggatttgat gattcaaaac tagaatagct
    18661 tttgtcgatt caagtaaagc tgttttgtct ttactcttag cagaaagttg atctaataat
    18721 gcatccacct tatcaaagtc cgcatcagat ccattattac tttctaaata agagtgaagc
    18781 gacatgagaa tatcgtagag tttttgatag agtacaagtg tctgagaatc ttgctcagca
    18841 ttttcctttt cttgttgaag ggcgctagcg atacgagtca agacatcttt tacctgactg
    18901 tttacttcat ccaagtctgc atcagccttg tttgtggcag cttttagatt ttctacttct
    18961 tctgccaagg attgtctgat tccttcttca tggatttgtt ccaagagttg atttaccttg
    19021 ctcaaaagac tttctacttc ttccttgcta tctgtcgcag attattggtt gccatctacc
    19081 atgtactcct aaaacaggag agttataatc caagattaca aggccttaca gaaataagaa
    19141 atccagataa gacaatgttc gtccaagacg ctattcgctt cgcacagcag cacggattca
    19201 atatgcttta attttaaagt ttaggtgtca agacctcttt ttagtgtgcc caaaatttag
    19261 agaagtaatc aatcaactaa cttttatttt tttcaaactt tcagtaaact gacctaaagc
    19321 taactcaatc tgtctttgta gatgcttctg ctatcagcta gaagttgatc tacttttgcc
    19381 aagactgcct tctcatcaaa agttccaggt tgatagttgg attgcaggga tggaatcttg
    19441 tttttcaaag ccgcttcata tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca
    19501 tgaggaatca caaaaccttc tgaatcttca cttataattc gattggcatc aaaaccatga
    19561 ccatcttctt cctcatgatg gacatgtagt gacggattac ttaatacaga actagaagaa
    19621 cttcctacct cttccgtgtt agagtgtgat gggggattgt taagagatga cttaggaata
    19681 tagtgatagt gatccccatg tcttactata taagcatcac ctgtatctct gacaatatca
    19741 ttagggttaa agacatatgt ggctgctaat tcacctgccg acaagtcact ctcaggaatg
    19801 aaatgatagt gaccaccatg tggtactata gtagattgaa atagaatatg agcaaattga
    19861 taaggggatt ttaaagtaat ttctaacaat gatttagaaa ctatgatgtg ctattctaaa
    19921 ttcaactcac tatatataac catcatcggt agtataacgt ccctgtaatt ttgctacaga
    19981 tacttctgca ctagctcctt tatcgtcttt accatgttct tgtttttggc gattgatttc
    20041 atcttttgtt cgtacatttt ctgcatgagc ttgatcttta aggtaaacat aatactttcc
    20101 atctacctta ataatatatc ctcccttaac ctaactgacg atatcttgat ctttcggctg
    20161 atagttgggg gctttcatta atagctcttc actaaagagc gcatcaaaag gaactttacc
    20221 attatagtag tgataatgat cgccatgaga agttacataa ccttgatctg taatcttaat
    20281 aacaatttgt tttgcttgaa ttccttcttt ttgactaacc tagtctggag tcaaattttc
    20341 agtcttctta gtgtctttat tactgtttac atatgaaaca cgatttttat ctgtattggc
    20401 ctgttagcta tgttggttca gagcataaac acacagactt aaggaaagga taacaacaga
    20461 tccagctgct atatatttct ttttaaattt cataattacc tcatttctat aattatttat
    20521 atgatgtctt cattattaaa tgattaaata aattaattaa ccaattaatt aactagtaaa
    20581 tattccacct ctttttaagt tgtatgtcaa gaaattttat atattaataa taaaatgaaa
    20641 ttctcccaaa gtcagagttt tatttctaac ttttgagaga acttcatttt tgattcagac
    20701 tttttctact gctattcctt acgctatgag atcagataaa ttctttttta tcacttctcc
    20761 acttggcaat cttaattcaa tcgttccatc catattgaat ataacactat ctaagcctaa
    20821 tccgtaacta gctgtaaatt tttctaattt ttcttgtaca ggatctactg ctggagcttc
    20881 ctctaatgct ggatctaaca tagggtcact ccccacattc ccttctggat tcaacattcc
    20941 attatccgtt gagttttctg gttttacagg tttttcgttt ggtgcctctg gtaaagaatc
    21001 tgctggttta ttttctgttg gttggttctc aactgttcca gtagatactt ttccattttc
    21061 agatggttta ttttcaccat ttccttgagg tgcttctcct gtaaaatctg ccatattctt
    21121 tttaatgact tctcccgatg gtaaatataa ttcaattgtt ccgtccatat taaacaagac
    21181 attttctagc ttcatcccat aactttcagc aaattttgct actttttctt gtacaggatc
    21241 cactgtagga acttcttcta acgttgaatt actagtacta ttcccagttt cagaaagttt
    21301 ttctttttct accttctcac tagtctttgg ttcttctacc ttttcatcaa gttttgagtt
    21361 ttcttgtgct ttattccttt taaattgtgg tagaatactt ggtttatcag tttgattttc
    21421 tttttccaag ataggtactt ccacaatata agtcgattga ttgtccaaat aagcatttgc
    21481 catgaaggtt acaggaattt tatttccggc cgttctggtt gttccttggt ttaatttcgg
    21541 aatcggtaat ttgatttcac caactttata gttattttct aaataagcat ttccatgaaa
    21601 ttcatcaaac actctgacta aagcatcagt tcctttaggc actgcaaatt gagggttcac
    21661 tcttaaataa gtatcccctg catggaaagg atagaaaatc gtttgactgg ccattttgta
    21721 agctaaagag gttggaactg taaatgtacc atcataactt acttctggat aatcttttga
    21781 agcgatagta tacttaaatg tttgtcctgg taaataaggt tgatctaatt caaagtttgc
    21841 aatattccct actccttctc caaatacttt accagatact ttctccaata cttttccatc
    21901 tggtgttatt aattttacta gcatattgat acctaatttt ttctccaatt caggcggaaa
    21961 actaaaagaa acgcgttttt gaccattggc tagagtaaag ttttgattat taaacgtact
    22021 attttttaac aaattaacaa cattcgttaa ttcttctcca gtataaactt tattcccttc
    22081 ttttttagca actccttctt cgggtttaaa cagttcatag ttactgtgag aatgaccaat
    22141 tccaaccggt ttatgttcat caatcggatc tgcatgatgg tgatctccat gcggataaat
    22201 aatcgcattt ttttctttat tcacgacaat actttcacgt ttgacaccat attgtttcat
    22261 aatgccagca attttttctt cgattttttt atctaaatct ttcatttctt tggcattact
    22321 tggataatcc tgttcatgag atgacaaaga atctaatcca ttatgactag ttttaacttc
    22381 ctctaaatgt ttttgcgcag ccttaatttg ctcttctgtc aagtccttct tgaagaaata
    22441 atgattgtgg tctccgtgac tcatgacaaa acctgattca tcttcagcga taatacgatt
    22501 agcatcaaat ccgtatccat cttcttcatg tttctcatgt gaagttcctg gattgattgg
    22561 aagagatgga gaaggtgttg ctagactatt gtttggaaga gtcggttgcc caatttgatt
    22621 tgattttgga atgtaatgga aatgatcacc atgtcttaca atataagctg tagccgtttc
    22681 ttcaacgata tcttttggat taaaaatata accatcagat gctgaagaga gctccttact
    22741 tgtcgttaaa gaagaaggat tgcttgaaag actgcctaga ctagacacta cttcattagg
    22801 ttttgcattt gtagaaactg tagaaccagt tccactgata ggcaccattc tggcaatctt
    22861 ttcttctaag gcagaaagct tgctgtaagg aataaagtgg taatggtcgc catgcggaat
    22921 cgcaactcca tttggtgtac gactgataat cttagcaggg tcaaagacca ggccatctga
    22981 ttcactgtaa cgttgggcgc taggtgaatc atagagttcc ttcaaaagac tctggagatt
    23041 ttcagattta tttgctggct tgctagttga tccttttgct acagattgcg tgttattgtc
    23101 actagctgtt gaagaatagc ttaactgact cggttgcata ttttttccag ccagatgtgc
    23161 tttagctgct gctaattcac tagcagataa atcgcttttg ggaatgtagt gatagtgacc
    23221 tccatgagga acgatataag cattacccgt atcttcgata atatcagctg gattaaagac
    23281 ataaccatca tttgtcgtat atcgtccctg agaccttgct acagcaacat tagagttaac
    23341 cttctcatta tctttgacat gttcttgttt ttgacgattg atttcatctt tagttcgaac
    23401 attatcagca tgagctgcat ctttcaggta gacataatat tttccatcga ccttgatgat
    23461 ataaccaccc ttgacttcat tgacaatatc agcgtcttta agttgatagt ttggatcctt
    23521 catcaagagt tcttcactaa agagggcatc ataaggaact ttcccattat agtaatgata
    23581 gtggtcaccg tgtgacgtta catagccctg atctgtaatt ttgattacaa tttgctcagc
    23641 ctgaattcct tctttctggc taacctggtc tggtgtcaag ttttcacttt tctgacttga
    23701 ctggctgcca tccacataag agacacgatt attgtcctta ttttcctgcg aacgatgctg
    23761 gtttagtgca taggcacata gactcaagga tacgataaca gctgatccag ctgctatata
    23821 ttttttacta aatttcataa atccctcatt tcaataaatg atgaagtttt ttctcaactt
    23881 cttttacttt attaaatagt tttctaaacc ggttatttaa ccatttaatt aaccagtaaa
    23941 tagtttacta tttaaaatta cttttgtcaa gtttctgtta cgtttttcta aaaaagagaa
    24001 gtaacacgaa aggttacttc tccataaaat atgctccatt cattttacta ctgtatagga
    24061 gccggttgac ttttttttaa caaagccaag agactatcta cttctgctga aatagtgtta
    24121 ttatctttcg ttccgagaag aagactactt tttagaccag tcaatgtctc catagcattt
    24181 tgtctaatac tag
//
LOCUS       DAVLAQ010000028        22666 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000028 DAVLAQ010000000
VERSION     DAVLAQ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22666
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.028"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..160
                     /locus_tag="VXB71_001208"
                     /pseudo
     CDS             1..160
                     /locus_tag="VXB71_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            555..941
                     /locus_tag="VXB71_001209"
     CDS             555..941
                     /locus_tag="VXB71_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase"
                     /protein_id="HEV0451325.1"
                     /translation="MFAWFLFYEVGSKKDYVSYINPGLWGIAFIVCVLVAFAIFPKME
                     KNFPKTFLYFTKYGKDSLGIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLS
                     ILATYILKKIPFLNIVLLPQKYIKLK"
     gene            1119..3101
                     /locus_tag="VXB71_001210"
     CDS             1119..3101
                     /locus_tag="VXB71_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0451326.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKVLDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            3402..8705
                     /locus_tag="VXB71_001211"
     CDS             3402..8705
                     /locus_tag="VXB71_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0451327.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDERDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KQALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEITVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(8872..11031)
                     /locus_tag="VXB71_001212"
     CDS             complement(8872..11031)
                     /locus_tag="VXB71_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0451328.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(11028..11624)
                     /gene="recU"
                     /locus_tag="VXB71_001213"
     CDS             complement(11028..11624)
                     /gene="recU"
                     /locus_tag="VXB71_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0451329.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            11690..12217
                     /locus_tag="VXB71_001214"
     CDS             11690..12217
                     /locus_tag="VXB71_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0451330.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            12287..12616
                     /gene="gpsB"
                     /locus_tag="VXB71_001215"
     CDS             12287..12616
                     /gene="gpsB"
                     /locus_tag="VXB71_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0451331.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            12637..13017
                     /gene="rnpB"
                     /locus_tag="VXB71_001216"
     ncRNA           12637..13017
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXB71_001216"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13102..14259
                     /locus_tag="VXB71_001217"
     CDS             13102..14259
                     /locus_tag="VXB71_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0451332.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREMRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            14272..15666
                     /gene="mapZ"
                     /locus_tag="VXB71_001218"
     CDS             14272..15666
                     /gene="mapZ"
                     /locus_tag="VXB71_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0451333.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLGKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            15742..17166
                     /gene="gndA"
                     /locus_tag="VXB71_001219"
     CDS             15742..17166
                     /gene="gndA"
                     /locus_tag="VXB71_001219"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0451334.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPYLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            17178..17867
                     /locus_tag="VXB71_001220"
     CDS             17178..17867
                     /locus_tag="VXB71_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0451335.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGIGYTMQE"
     gene            17965..18987
                     /gene="cbpC"
                     /locus_tag="VXB71_001221"
     CDS             17965..18987
                     /gene="cbpC"
                     /locus_tag="VXB71_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0451336.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            19005..20003
                     /gene="cbpJ"
                     /locus_tag="VXB71_001222"
     CDS             19005..20003
                     /gene="cbpJ"
                     /locus_tag="VXB71_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0451337.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(20121..21353)
                     /locus_tag="VXB71_001223"
     CDS             complement(20121..21353)
                     /locus_tag="VXB71_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0451338.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(21396..22358)
                     /locus_tag="VXB71_001224"
     CDS             complement(21396..22358)
                     /locus_tag="VXB71_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0451339.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLFLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
BASE COUNT         7068 a         3996 c         5034 g         6568 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccgct aatagctgaa gataaagcct ataaccatgc
       61 actgtctaag gatagaagca aggttgagaa catccttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga tattttaggc atactatata
      181 ttttttattc aattattcac ttttgtattc aaaaggttgc gggtgcctct gtccgagtac
      241 ccactatgat atttaaccta ttgaatatct ataaatttcc tctgggagtt tcatggtatc
      301 tatatacgtt atggtcgata ttgatagttt atggtttact atctgttgtt ttcaaaaatc
      361 gtaagtccct tttgttagtt agtgtttttg cctatatttt cacactattt attcaaactg
      421 atatttttat tgtgcaacgg acgttggttt gggggatttg tttctttctt ggcagtgtat
      481 tgagtgaaat tcactttgat aaaattaatt tgaaaaaatt tctttttttc tttgtgttat
      541 ttgattttat ttatatgttc gcttggttct tgttttatga agtagggtct aagaaggatt
      601 atgtaagcta tattaaccca ggtttgtggg ggattgcttt tattgtctgt gtattagttg
      661 cttttgcgat ttttcctaaa atggagaaaa attttcctaa aactttccta tatttcacta
      721 aatacgggaa agatagttta gggatctata ttcttcatgc accaatttgt agcatgattc
      781 ggattctaat gttgaaagtg ggaataaact cagtttttct tcacgttgtt gttgggattg
      841 tgctaggctg gtatttatcc atactagcaa cttatatatt gaaaaaaatt ccatttttga
      901 atattgtttt attaccacaa aagtatatta aattaaaata aattatttta gatttataat
      961 gtggctcttt gtcaactaac atctggagag gacaatcact gtcttctctt tttttgtctt
     1021 ttcagaatat accaaattaa cacaaaaatt ctgaaaattc tgttgacatc tttctgaaaa
     1081 gagtttataa tggagagaaa gttttaaagg agaaaatgat gaaaagttca aaactatttg
     1141 cccttgcggg cgtgacatta ttggcggcga ctactttagc tgcatgctct ggatcaggtt
     1201 caagcactaa aggtgagaag acattctcat acatttatga gacagaccct gataacctca
     1261 actatttgac aactgctaag gctgcgacag caaatattac cagtaacgtg gttgatggtt
     1321 tgctagaaaa tgatcgctac gggaactttg tgccgtctat ggctgaggat tggtctgtat
     1381 ccaaggatgg attgacttac acttatacta tccgtaagga tgcaaaatgg tatacttctg
     1441 aaggggaaga atacgcggca gtcaaagctc aagactttgt aacaggacta aaatatgctg
     1501 ctgataaaaa atcagatgct ctttaccttg ttcaagaatc aatcaaaggg ttggatgcct
     1561 atgtaaaagg ggaaatcaaa gatttctcac aagtaggaat taaggttctg gatgaacaga
     1621 cagttcagta cactttgaac aaaccagaaa gcttctggaa ttctaagaca accatgggtg
     1681 tgcttgcgcc agttaatgaa gagtttttga attcaaaagg ggatgatttt gccaaagcta
     1741 cggatccaag tagtctcttg tataacggtc cttatttgtt gaaatccatt gtgaccaaat
     1801 cttctgttga atttgcgaaa aatccgaact actgggataa ggacaatgtg catattgaca
     1861 aagttaaatt gtcattctgg gatggtcaag ataccagcaa acctgcagaa aactttaaag
     1921 atggtagcct tacagcagct cgtctctatc caacaagtgc aagtttcgca gagcttgaga
     1981 agagtatgaa ggacaatatt gtctatactc aacaagactc tattacgtat ctagttggta
     2041 caaatattga ccgtcagtcc tataaataca catctaagac cagcgacgaa caaaaggcat
     2101 cgactaaaaa ggctctctta aacaaggatt tccgtcaggc tattgccttt ggttttgatc
     2161 gtacagccta tgcctctcag ttgaatggac aaactggagc aagtaaaatc ttgcgtaatc
     2221 tctttgtgcc accaacattt gttcaagcag atggtaaaaa ctttggcgat atggtcaaag
     2281 agaaattggt cacttatggg gatgaatgga aggatgttaa tcttgcagat tctcaggatg
     2341 gtctttacaa tccagaaaaa gccaaggctg aatttgctaa agctaaatca gccttacaag
     2401 cagaaggtgt gacattccca attcatttgg atatgccagt tgaccagaca gcaactacaa
     2461 aagttcagcg cgtccaatct atgaaacaat ccttggaagc aactttagga gctgataatg
     2521 tcattattga tatccaacaa ctacaaaaag acgaagtaaa caatattaca tattttgctg
     2581 aaaatgctgc tggcgaagac tgggatttat cagataatgt cggttggggt ccagactttg
     2641 ccgatccatc aacttacctt gatatcatca aaccatctgt aggagaaagt actaaaacat
     2701 atttagggtt tgactcaggg gaagataatg tagctgctaa aaaagtaggt ctatatgact
     2761 acgaaaaatt ggttactgag gctggtgatg aggctacaga tgttgctaaa cgctatgata
     2821 aatacgctgc agcccaagct tggttgacag atagtgcttt gattattcca actacatctc
     2881 gtacagggcg cccaatcttg tctaagatgg taccatttac aataccattt gcattgtcag
     2941 gaaataaagg tacaagtgaa ccaatcttat ataaatactt ggaacttcaa gacaaggcag
     3001 tcactgtaga tgaataccaa aaagctcagg aaaaatggat gaaagaaaaa gaagagtcta
     3061 ataaaaaggc tcaagaagat ctcgcaaaac atgtgaaata actgttgcaa aatataagaa
     3121 aggatttagt atttctcttg aatgctgaat ccttttttac atttgtaaag aaagattcta
     3181 aatgtactga cccccaaaag ttggagcctc tttttgtcag aatagagaaa atttttgtta
     3241 attttacttg tttcctattg ctttatcagt tattatttgt tatattaaaa gtataattat
     3301 tttttattta tcagggttaa gcattgcact ttcagaggaa ggagtatttt ttaaaaagga
     3361 aatgtaaacg cttgcccaaa aatgaaagga tttagaagtt tatgaataaa ggattatttg
     3421 aaaaacgttg taaatatagt attcggaaat tttcattagg tgttgcttct gttatgattg
     3481 gagctgcatt ctttgggaca agtccggttc ttgcagatag cgtgcagtct ggttctacgg
     3541 cgaatttacc agctgattta gctactgctc ttgcaacagc aaaagagaat gatgagcgtg
     3601 attttgaagc gcctaaggtg ggagaagacc aaggttctcc agaagttaca gatggaccta
     3661 agacagaaga agaactatta gcacttgaaa aagaaaaacc ggctgaagaa aaaccaaaag
     3721 aggataaacc tgcagctgct aaacctgaaa cacctaagac ggtaacccct gaatggcaaa
     3781 cggtagagaa aaaagaacaa caaggaacag tcactatccg agaagaaaaa ggtgtccgct
     3841 acaaccaact atcctcaact gctcaaaatg ataacgcagg caaacaagcc ctgtttgaaa
     3901 agaagggctt gaccgttgat gccaatggaa atgcaactgt tgatttaacc ttcaaagaag
     3961 attctgaaaa gggcaaatca cgctttggtg tcttcttgaa atttaaagat accaataata
     4021 atgtttttgt cggttatgac aaggatggct ggttctggga gtataaatct ccaacaacta
     4081 gcacttggta tagaggtagt cgtgttgctg ctcctgaaac aggatcaaca aaccgtctct
     4141 ctatcactct caagtcagac ggtcagctaa atgccagcaa taacgatgtc aatctctttg
     4201 acacagtgac tctaccagct gcggtcaatg accatcttaa aaatgagaag aagattcttc
     4261 tcaaggcggg ctcttatgac gatgagcgaa cagttgttag cgttaaaacg gataaccaag
     4321 agggggtaaa aacagaggat acccctgctg aaaaagaaac aggtcctgaa gttgatgata
     4381 gcaaggtgac ttatgacacg attcagtcta aggtcctcaa agcagtgatt gaccaagcct
     4441 tccctcgtgt caaggaatac agcttgaatg gacatacttt gccaggacag gtgcaacagt
     4501 tcaaccaagt ctttatcaat aaccaccgaa tcacccctga agtcacttat aagaaaatca
     4561 atgagacaac agcagagtac ttgatgaaga ttcgcgatga tgctcactta atcaatgcgg
     4621 aaataacagt acgcttgcaa gttgtggaca atcaattgca ctttgatgtg accaagattg
     4681 tcaaccacaa tcaagtcact ccaggtcaaa agattgatga cgaaagaaaa ctactttctt
     4741 ctattagttt cctcggcaat gctttagtct ctgtttctag tgatcaaact ggtgctaagt
     4801 ttgatggggc aaccatgtca aacaatacgc atgtcagcgg agatgatcat atcgatgtaa
     4861 ccaatccaat gaaggatttg gctaagggtt acatgtatgg atttgtttct acagataagc
     4921 ttgctgctgg tgtttggagt aactctcaaa atagctatgg tggtggttcg aatgactgga
     4981 ctcgtttgac agcttataaa gaaacagtcg gaaatgccaa ctatgtagga atccatagct
     5041 ctgaatggca atgggaaaaa gcttataagg gcattgtttt cccagaatac acgaaggaac
     5101 ttccaagtgc taaggttgtt atcactgaag atgccaatgc agacaagaaa gttgattggc
     5161 aagatggtgc cattgcttat cgtagcatta tgaacaatcc tcaaggttgg gaaaaagtta
     5221 aggatatcac agcttaccgt atcgcgatga actttggttc tcaagcacaa aacccattcc
     5281 ttatgacctt ggatggtatc aagaaaatca atctccacac agatggtctt gggcaaggtg
     5341 ttctccttaa aggatatggt agcgaaggcc atgactctgg tcacttgaac tatgctgata
     5401 ttggtaagcg tatcggtggt gtcgaagact tcaagaccct aattgagaag gctaagaaat
     5461 atggagctca tctaggtatc cacgttaacg cttcagaaac ttatcctgag tctaaatact
     5521 tcaatgaaaa aattctccgt aagaatccag atggaagcta tagctatggt tggaactggc
     5581 tagatcaagg tatcaacatt gatgctgcct atgacctagc tcatggtcgt ttggcacgtt
     5641 gggaagattt gaagaaaaaa cttggtgacg gtctcgactt tatctatgtg gacgtttggg
     5701 gtaatggtca atcaggtgat aacggtgcct gggctaccca cgttcttgct aaagaaatta
     5761 acaaacaagg ctggcgcttt gcgatcgagt ggggccatgg tggtgagtac gactctacct
     5821 tccatcactg ggcagctgac ttgacctacg gtggctacac caataaaggt atcaacagtg
     5881 ccatcacccg ctttatccgt aaccaccaaa aagatgcttg ggttggggac tacagaagtt
     5941 atggtggtgc agccaactat ccactgctag gtggctacag catgaaagac tttgaaggct
     6001 ggcaaggaag aagtgactac aatggctatg taaccaactt atttgcccat gacgtcatga
     6061 ccaagtattt ccaacacttc actgtaagca aatgggaaaa tggtacaccg gtgactatga
     6121 ccgataacgg tagcacctat aaatggactc cagaaatgcg agtggaattg gtagatgctg
     6181 acaataataa agtagttgta actcgtaagt caaatgatgt caatagtcca caatatcgcg
     6241 aacgtacagt aacgctcaac ggacgtgtca tccaagatgg ttcagcttac ttgactcctt
     6301 ggaactggga tgcaaatggt aagaaacttt ctactgataa ggaaaagatg tactacttca
     6361 atacgcaggc cggtgcaaca acttggaccc ttccaagcga ttgggcaaag agcaaggttt
     6421 acctttacaa gctaactgac caaggtaaga cagaagagca agaactaact gtaaaagatg
     6481 gtaaaattac tctagatctt ctagcaaatc aaccatacgt tctctatcgt tcgaaacaaa
     6541 ccaatcctga aatgtcatgg agcgaaggca tgcacatcta tgaccaagga tttaacagtg
     6601 gtaccttgaa acattggacc atttcaggcg atgcttctaa ggcagaaatt gtcaagtctc
     6661 aaggggcaaa cgatatgctt cgtattcaag gaaacaaaga aaaagttagt ctcactcaga
     6721 aattaactgg cttgaaacca aataccaagt atgccgttta tgtcggtgtc gataaccgta
     6781 gtaatgccaa ggcgagcgtc actgtaaata ctggtgaaaa agaagtgact acttatacca
     6841 ataagtctct cgccctcaac tatgtaaaag cctacgccca caatacacgt cgtaacaatg
     6901 ctacagttga cgatacaagt tacttccaaa acatgtacgc cttctttaca actggatcgg
     6961 acgtatcaaa tgttactctg acattgagtc gtgaagctgg tgatcaagca acttactttg
     7021 atgaaattcg tacctttgaa aacaattcaa gcatgtacgg agacaagcat gatacaggta
     7081 aaggcacctt caagcaagac tttgaaaatg ttgctcaggg tatcttccca tttgtagtgg
     7141 gtggtgtcga aggtgttgaa gataaccgca ctcacttgtc tgaaaaacac aatccatata
     7201 cacaacgtgg ttggaatggt aagaaagtcg atgatgttat cgaaggaaat tggtcactca
     7261 agacaaatgg actagtgagc cgtcgtaact tggtttacca aaccatccca caaaacttcc
     7321 gttttgaagc aggtaagacc taccgtgtaa cctttgaata cgaagcagga tcagacaata
     7381 cctatgcttt tgtagtcggt aagggagaat tccagtcagg tcgtcgtggt actcaagcaa
     7441 gcaacttgga aatgcatgaa ttgccaaata cttggacaga ttctaagaaa gccaagaagg
     7501 caaccttcct tgtgacaggt gcagaaacag gcgatacttg ggtaggtatc tactcaactg
     7561 gaaatgcaag taatactcgt ggtgattctg gtggaaatgc caacttccgt ggttataacg
     7621 acttcatgat ggataatctt caaatcgaag aaattaccct aacaggtaag atgttgacag
     7681 aaaatgctct gaagaactac ttgccaacgg ttgccatgac taactacacc aaagagtcta
     7741 tggatgcttt gaaagaggcg gtctttaacc tcagtcaggc cgatgatgat atcagtgtgg
     7801 aagaagcgcg tgcagagatt gccaagattg aagctttgaa gaatgctttg gttcagaaga
     7861 aaacggcttt ggtagcagat gactttgcaa gtcttacagc tcctgctcag gctcaagaag
     7921 gtcttgcaaa tgcctttgat ggcaatgtgt ctagtctatg gcatacatct tggaatggtg
     7981 gagatgtagg caagcctgca accatggtct tgaaagaacc aactgaaatc actggacttc
     8041 gttatgttcc acgtggatca ggttcaaatg gtaacttgcg tgatgtgaaa cttgttgtga
     8101 cagatgagtc tggcaaggag cataccttta ctgcaactga ttggccagat aacaataagc
     8161 caaaagacat tgattttggt aagacaatta aggctaagaa aattgtcctt acaggtacta
     8221 agacttacgg agatggtggc gataaatacc aatctgcagc ggaacttatc tttactcgtc
     8281 cacaggtagc agaaacacct cttgacttgt caggctatga agcagctttg gctaaggctc
     8341 agaaattaac agacaaagac aatcaagagg aagtagctag cgttcaggca agcatgaaat
     8401 atgcgacgga taaccatctc ttgacggaaa gaatggtgga atactttgca gattatctca
     8461 accaattaaa agattctgct acgaaaccag atgctccaac tgtagagaaa cctgagttta
     8521 aacttagctc tttagtttcc aatcaaggta agacgccaga ttataagcaa gaaatagata
     8581 gaccagaaac acctgaacaa atcttgccag caacaggtga gagtcaatct gacacagccc
     8641 tcttcctagc aagtgttagt ctagccctat ctgctctctt tgtagtaaaa acgaagaaag
     8701 actagtattt agtaaaacct cttaacaaga ttacggaagc agtctctatc ttttccaatg
     8761 aggtttatag tacagaaaaa gcctgagaag atgtcttctc aggcttttgt taagcacata
     8821 aatacaatag tgctatgaca aaatcaccca gaaaaatctg ggtgataaat gttatggttg
     8881 tgctggttga ggattctgat tttgttgatc aggggttgta tttgattgtt gcgtattatt
     8941 gttaggattg gtagtcgtac tattatttgt gcttggagtg gttgagctag actgtgaagt
     9001 tgaactatct gatgatgagc ttgaactttc agttgatggg ggttgttgtg gagcaggtga
     9061 gttccacgta gaacgagcac catttttaaa tacgaattct ccatttctgt agagcccctc
     9121 tggtatattc caatcctctg gattgcttcc ttcagacaga taggtcatca tagagcggta
     9181 aactttggca gcgaccgtaa ggccattgcc tacaagtggt gtcagacggt tagaatagcc
     9241 tgtccataca gccattgaat atttacgcgt atagccagca aatagttcat caggtgctac
     9301 aaattgagag gtcttgatgt ggttttcaat ttcctcgtct gtatagttag aggttcctgt
     9361 tttaccagcc tgagggagcc aagcaagata ggcatttcgt ccagttccat aactcaagac
     9421 tgttttcatc atgtcggtca tcatataggc tgtcgtttcc ttcatggcac gagttccgac
     9481 attagagaac tctttttcac tcccatcact aaagacgact ttatggatat acattggttt
     9541 atagtaagtt ccaccatttg caaaggcagc gtaagcagca gccatctttt cactacttgc
     9601 tccatatttt ttgtctgatt cggttgtgtt acttgaaatg gcatttgagt agtgaatact
     9661 tgggtagtcg attccgagac catttaggaa agtcttggcg cggttgagtc cgaccttgtt
     9721 tagagtttcc acggctggga cgtttcgcga ttgttgcagg gcgtattgca aggtgatgtt
     9781 gccaaagtag cccctatccc agttataaac aggggtattt gtcccagggt agttataggg
     9841 ctcatcgtga acgatagtag cagttgaatc gtagataccg tactccaagg caggagcata
     9901 gtctgtgatc ggtttcatag ttgatcccca gtcgcggttt gtttctactg cttggttaat
     9961 tccgaaggaa acattacttg actgatggcg tgctcctagc tgggcaatga ctttaccgtt
    10021 agaaacatca acaatggtag aagcgacttg caattcatcg tctggatagg caacgtattc
    10081 gtctgtattg taaatatccc acagatgttt ttgagcttct tggtctacat ttgtgtagac
    10141 atccatccca gttgtgagca ggttatagcc tgtttcttct tcaacttgat tgatgacttc
    10201 cttgaggtaa ttatccatgt aagcagggta attacttgct gatttgagac tttgtagtcc
    10261 atcagtaatt ggtgtattga ctgctttctc atactgttca gcagagatgt agccttgatt
    10321 tttcatttca gataagacca agtttcggcg gtcttgggct gcttctggat gtgaataggg
    10381 gtcatattgg tttggtgcct gaggcattcc agccagcaag gctaactgag gtaaacttaa
    10441 attattgagg tctttaccat agtagttttg agctgctgtc tgcattccat agttcccatt
    10501 agacatgtag accttattta tatagtaggt caagatttct tgcttggttg ctttttgttc
    10561 taactgaatc gctaaccaag cttcctgagc cttacgagaa atagtctggt cggaagtcga
    10621 agttgaaaag taagtcaact taatcaactg ttgggtgaga gttgatccac cttggaggga
    10681 attgctttgc agattgcgca agaaagctcc taggatacgg atggtatcaa tccccctgtg
    10741 gtcgaagaag cgatggtctt cgatagaaac gattgcctta accaaatctg tgggaatatc
    10801 attagcttgg gcattgacgc ggcgttcaga acccaagtca gcaatgagtt gatttttatt
    10861 gtcgtagatt ttactagaag ttgttgcaac tagtttactc tcggataggc taggagcctt
    10921 gctaacgtag tagaaaaaaa ctcctccgcc taagacaatg gctgcgataa ccaagcttaa
    10981 gaagctaatg ctcagatact tgattaggcg cagaatcgtt ggtttgttca tcttgtttta
    11041 ccacctaata aatgttcttt gataacattg agataaggaa tttgagggaa ggcaccagcc
    11101 ttgatttcat atccatattc tcgaatatat tcaagtggca ttgatttttg tcccttatct
    11161 tgatgataga agcgaatcaa atcgaatgcc ggcaataagt aggtttcttg ctgagaagaa
    11221 aagtgaagaa ggacaaagca gattccttgt tgggcaagga cttgttccat atgctgaatc
    11281 tgatgtggat gaaaattttt catcggaatc gcacgttttt gttttgtttc cttgacttca
    11341 aagtcgatgt aatatccatt ataaacgcca gaatagtccg tcgttgaagc ttgtcgaaaa
    11401 taggcttcaa caatcttggc acgacttcgt tgtggatagt ccacttgtac gatttgaata
    11461 ggagttggtt tcttatgtat aacagccaag ccctgagaca aatagtagtc gttggtagca
    11521 ttgatcatct tttcaaaaga cattcctcga tttgcgaaat ttttgggttg agaaagagat
    11581 gtttgtcttt tttgtgatga aactttatgt ggatagttga ccataattct ccttattggt
    11641 acaataacat cactttatta taccataatt tgcacagaaa gggttaaaaa tggctacagc
    11701 tttggtttta ggctattctg cttttgattt gggtttattt tctgataagg atcctcgtct
    11761 taaattgatt aaaaaagcga tacgtaaaga tttagaggct atggcagcag atggggtgtc
    11821 ttggcttgtg tttacaggga gtttgggttt tgaatattgg gttttagagg ttgctcagga
    11881 gatgaaaact gaatacggtt tccagttggc caccattttt gcttttgaaa cccatgggga
    11941 aaattggaat gaaggcaatc agatgaaact gagtcgcttt aagcaggtag actttgtcaa
    12001 atatgcctat cctcgctatg aacacaaggg gcagttaaga gattaccagc agtttttgct
    12061 ggaaaacacg actagttcct atctttttta tgatgaagaa aatgaaacaa aactagctta
    12121 tttttaccaa aagatgaaaa atcaagagga ctattttata aagagattaa catttgatga
    12181 attaaatgaa cttgctgaaa atttttccga aaattgaagc tttgaccttg atttttgttt
    12241 gccttttttt atataataat actagcaagc gagaatggag agagacatgg caagtattat
    12301 tttttcagcg aaagatattt ttgaacaaga gtttggacgt gaagtccgtg gctataataa
    12361 agtagaagtt gacgagtttt tagacgatgt catcaaggac tatgaaacct atgctgcctt
    12421 ggtcaagtca cttcgtcagg aaattgcgga tttgaaggaa gaattaactc gtaaaccgaa
    12481 accttcacca gttcaagcag aaccccttga agcggcaatt acaagttcta tgacgaattt
    12541 tgatattttg aaacgcctga atagattgga aaaagaagtt tttggtaaac aaattttaga
    12601 taactcagat ttttaagtag ttatttgaga tgtgcaattt ttggataatc gcgtgaggag
    12661 aattgcttct catgaggaaa gtccatgcta gcacaggctg tgatgcctgt agtgtttgtg
    12721 ctaggcgaaa ccataagcct agggacgaga aatcgttacg gcagttgaaa tggctaagtc
    12781 cttggatagg ccagagtagg cttgaaagtg ccacagtgac ggagtctttc tggaaacaga
    12841 gagagtggaa cgcggtaaac ccctcaagct agcaacccaa attttggtcg gggcatggag
    12901 tacgcggaaa cgaacgtagt attctgactg ctatcagcta gagctgttag tggtagacag
    12961 atgattatcg aaggaagtgg tcctagtcac ttctggaaca aaacatggct tatagaaaat
    13021 tgcatatagg ttggggctga gaaattttct caacctcatt ttttaaagtg gacatataga
    13081 aaggtcttgc aagactgtaa catgaaaaaa gaatttaatt taattgcaac tgtggcagca
    13141 gggcttgagg ctgtcgttgg tcgtgaaatg cgagagttgg gctacgattg tcaggttgaa
    13201 aatggacgtg ttcgttttca aggagacgtg agagctatta tcgaaaccaa cctttggctt
    13261 cgggcagcag atcgtatcaa aattatcgta ggaacgttcc cagctaagac ttttgaagag
    13321 ctatttcagg gagttttcgc tttagattgg gaaaattatt taccacttgg agctcggttc
    13381 ccgatttcaa aagctaaatg tgttaagtcc aaacttcaca atgagcccag tgttcaggct
    13441 atttctaaga aagctgttgt caagaaattg cagaaacact atgctcgccc agaaggggtt
    13501 cctctgatgg agaatggtcc agagtttaag attgaggtct ctattctcaa agatgtggca
    13561 actgtcatga ttgatacgac cgggtctagc ctctttaaac gtggttatcg taccgaaaaa
    13621 ggtggcgctc ctatcaagga aaatatggca gcagccattt tacaactttc taactggtat
    13681 ccagacaagc ctttgattga tccgacctgt ggttcgggga ctttctgtat tgaggcagtt
    13741 atgattgcta gaaagatggc gccaggtctt cgtcgttctt ttgcatttga ggaatggaac
    13801 tggatcagcg atcgcttgat tcaagaagtg cgcacagaag cggctaaaaa agtagaccgt
    13861 gagcttgagc tggatatcat gggctgtgat attgatgctc gcatggtgga aattgctaag
    13921 gccaatgctc aggtagctgg tgttgcagga gacattactt ttaagcagat gcgcgtgcag
    13981 gatttatgtt ccgataaaat caatggagta atcatttcca atccgcctta tggtgaacgt
    14041 ttgtcagatg atgcaggggt gaccaagctc tatgctgaga tggggcaagt atttgcaccg
    14101 ctgaaaactt ggagcaaatt tatcctgact agtgatgaag cttttgaaag caagtatggt
    14161 agccaagcag ataagaagcg taagttatac aacggaacct tgaaagtgga tctatatcaa
    14221 tattttggtc agcgtgtcaa acggcaagag gtaaaataga aagggatact catgagtaaa
    14281 aaaagacgaa atcgtcataa aaaagaaggt caagaaccgc aatttgattt tgatgaagca
    14341 aaagagctaa cagttggtca agctattcgt aaaaatgaag aagtggaagc aggagtcttg
    14401 cctgaggatt ccattttgga caagtatgtt aagcaacaca gagatgaaat tgaggcggat
    14461 aagtttgcga ctcgtcaata caaaaaagag gagttcgttg aaactcagag tctggatgat
    14521 ttaattcaag agatgcgtga ggctgtagag aagtcagaag cttcttcgga ggaagttcca
    14581 tcttctgaag acatcttact acccttgcct ctggacgatg aggagcaagg cttggatcct
    14641 ctattgctag atgatgaaaa tccaacagaa atgactgaag aagtggaaga ggagcaaaac
    14701 ctttctcgtc tggatcaaga ggactcagaa aagaaaagta aaaaaggctt tattttgacc
    14761 gttttggcgc ttgtatcagt aattatttgt gtcagtgctt attatgtcta ccgtcaagtg
    14821 gctcgttcga ctaaggaaat tgaaacttct caatcaacta cagccaatca atcggatgtg
    14881 gatgatttta atacacttta tgacgccttt tacacagata gcaataaaac ggctttgaaa
    14941 aatagccagt ttgataaact gagtcaactc aagactttac ttgataagct ggaaggtagt
    15001 cgtgaacata cgcttgccaa atctaaatat gatagtctag taacgcaaat taaggccatt
    15061 caagatgtca atgcacaatt tgaaaaacca gctattgtgg atggtgtgtt ggataccaat
    15121 gccaaagcca aatcggatgc taaatttaca gatattaaaa ctgggaatac ggagcttgat
    15181 aaagtgctag gtaaggctat cagtcttggt aagagccagc aaacaagtac ttctagctca
    15241 agttcaagtc aaactagcag ctcaagctct agtcaagcaa gctcaaatac gactagtgag
    15301 ccaaaaccaa gtagttcaaa tgagactaga agtagtcgca gtgaagtcaa tatgggtctc
    15361 tcgagtgcag gggttgctgt tcaaagaagt gccagtcgtg ttgcctataa tcagtctgct
    15421 attgatgata gtaataactc tgcctgggat tttgcggatg gtgtcttgga acaaattcta
    15481 gcaacttcac gttcacgtgg ctatatcact ggagaccaat atatccttga acgtgtcaat
    15541 atcgttaacg gcaatggtta ttacaacctc tacaagccag atggaaccta tctctttacc
    15601 cttaactgta agacaggcta ctttgtcgga aatggcgctg gtcatgcgga tgacttggat
    15661 tactaagcag tcgttacaaa attctttctt ttcaaaagta aaaatgataa aataaaacaa
    15721 atgaaacaag aggagtgtca aatgacaaaa gctaactttg gtgttgtagg tatggccgta
    15781 atgggtcgta accttgccct taatattgaa tcacgtggtt acacagttgc tatctacaac
    15841 cgtagtaaag aaaaaacgga agatgtgatt gcttgccatc ctgaaaagaa ctttgtacca
    15901 agctatgacg ttgaaagttt tgtaaactca atcgaaaaac ctcgtcgtat catgctgatg
    15961 gttcaagctg gacctggtac agatgctact atccaagccc ttcttccata ccttgacaag
    16021 ggtgatatct tgattgacgg tggaaatact ttctacaaag ataccatccg tcgtaatgaa
    16081 gaattggcaa actcaggtat caactttatc ggtactgggg tttctggtgg tgaaaaaggt
    16141 gcccttgaag gtccttctat catgcctggt ggacaaaaag aggcctacga attggttgcg
    16201 gatgttcttg aagaaatctc agctaaagca ccagaagatg gcaaaccatg tgtgacttac
    16261 atcggccctg atggagctgg tcactatgtg aaaatggttc acaatggtat tgagtacggt
    16321 gatatgcaat tgatcgcaga aagctatgac ttgatgcaac acttgctagg cctttctgca
    16381 gaggatatgg ctgaaatctt tactgagtgg aacaagggtg aattagacag ctatttgatc
    16441 gaaatcacag ctgatatttt gagccgtaaa gacgatgaag gccaagatgg accaatcgta
    16501 gactacatcc ttgatgctgc aggtaacaag ggaactggta aatggactag ccaatcatct
    16561 cttgaccttg gtgtaccatt gtcactgatt actgagtcag tgtttgcacg ctacatttca
    16621 acttacaaag aagaacgtgt acatgctagc aaggtgcttc caaaaccagc tgccttcaac
    16681 tttgaaggag acaaggctga attgattgaa aagatccgtc aagcccttta cttttcaaaa
    16741 atcatttcat acgcacaagg atttgctcaa ttacgtgtag cctctaaaga aaacaactgg
    16801 aacttgccat ttgcagatat cgcatctatc tggcgtgatg gctgtatcat ccgttctcgt
    16861 ttcttgcaaa agattacaga tgcttacaac cgtgatgcag accttgccaa ccttcttttg
    16921 gatgaatact tcttggatgt tactgctaag tatcaacaag cagtgcgtga tatcgtagct
    16981 cttgcggttc aagctggtgt gccagtgcca actttctcag cagctattac ttactttgat
    17041 agctaccgtt cagctgacct tccagctaac ttgatccaag cacaacgtga ctactttggt
    17101 gctcacactt accaacgtaa agacaaagaa ggaaccttcc actactcttg gtatgacgaa
    17161 aaataagtag gtcagccatg gggaaacgga ttttattact tgagaaagaa cgaaatctag
    17221 ctcatttttt aagtttggaa ctccagaaag agcagtatcg ggttgatctg gtagaggagg
    17281 ggcaaaaagc cctctccatg gctcttcaga cagactatga tttgatgtta ttgaacgtta
    17341 atctgggaga tatgatggct caggattttg cagaaaaatt gagccgaact aaacctgcct
    17401 cagtcatcat gattttagat cattgggaag acttgcaaga agagctggaa gttgttcagc
    17461 gttttgcagt ttcatacatc tataagccag tccttatcga aaatctggta gcgcgtattt
    17521 cggcgatctt ccgaggtcgg gacttcattg atcaacactg cagtctgatg aaagttccaa
    17581 ggacctaccg caatcttagg atagatgttg aacatcacac ggtttatcgt ggtgaagaga
    17641 tgattgctct gacccgccgt gagtatgacc ttttggcgac acttatggga agcaagaaag
    17701 tattgactcg tgagcaattg ttggaaagtg tttggaagta tgaaagtgcg accgagacaa
    17761 atatcgtaga tgtctatatc cgctatctac ggagcaagct tgatgttaaa ggacaaaaaa
    17821 gctacattaa aactgtgcgt ggtattggat ataccatgca agaatagaaa agcagttgca
    17881 gttgtgtaac tgcttttttg aggagttttt atatattgac atgcagtcgg gtctttgcta
    17941 caatcgtttt aggaggatat atagatgaaa cttttgaaaa aaatgatgca agttctacta
    18001 gcagtctttt tctttggttt gctagctaca aatacggtat ttgcgaatac cacaggtggc
    18061 cgatttgttg ataaggataa tagaaaatat tatgtaaaag atgatcataa agcaatctat
    18121 tggcataaaa tagacggtaa aacttactat tttggtgata ttggagagat ggttgtcggt
    18181 tggcaatact tagaaattcc tggaacaggt tatcgtgata atttattcga taaccaacca
    18241 gttaatgaaa ttggccttca ggagaagtgg tactattttg gacaagatgg tgctttgcta
    18301 gaacaaacag ataaacaagt actagaggca aaaacgtctg aaaatacagg aaaagtatac
    18361 ggtgaacaat atcctctatc tgctgaaaag agaacttatt attttgataa taattatgct
    18421 gtaaagacag gctggattta tgaagagggt cattggtatt atttaaataa gctaggaaat
    18481 tttggcgatg attcttacaa tccactacca attggtgaag ttgctaaggg ttggactcaa
    18541 gattttcatg ttactattga cattgataga agcaaacctg ctccatggta ctacctagat
    18601 gcttcaggta agatgcttac agattggcaa aaagtaaacg gaaaatggta ttattttggc
    18661 tcctctggtt ctatggcaac aggttggaaa tatgtacgag gcaaatggta ttacttagat
    18721 aataaaaatg gtgatatgaa aacaggatgg caataccttg gtaacaagtg gtactacctc
    18781 cgttcatcag gagctatggt aactggctgg tatcaagatg gttcaacttg gtactattta
    18841 gatccttcta atggagatat gaaaataggt tggacaaaag taaatggaaa atggtattat
    18901 ctcaattcaa atggagcaat ggttacaggt agccaaacta tcgatggtaa agtttataat
    18961 ttcgcctcat ctggtgagtg gatttaatat tggagggtat atagatgaaa attttgaaaa
    19021 aaactatgca agttggactg acagtatttt tctttggttt gctagggacc agtacagtat
    19081 ttgcagatga ttctgaagga tggcagtttg tccaagaaaa cggaagaacc tactacaaaa
    19141 agggggacct caaagaaacc tactggcgag tgattgatgg taagtactat tattttgatt
    19201 ctctatctgg agagatggtt gtcggctggc aatatatccc gtttccatct aaaggtagta
    19261 caattggtcc ttacccaaat ggtatcagat tagaaggttt tccaaagtca gagtggtact
    19321 acttcgataa aaatggagtg ctacaagagt ttgttggttg gaaaacatta gagattaaaa
    19381 ctaaagacag tgttggaaga aagtacgggg aaaaacgtga agattcagaa gataaagaag
    19441 agaagcgtta ttatacgaac tattacttta atcaaaatca ttctttagag acaggttggc
    19501 tttatgatca gtctaactgg tattatctag ctaagacgga aattaatgga gaaaactacc
    19561 ttggtggtga aagacgtgcg gggtggataa acgatgattc gacttggtac tacctagatc
    19621 caacaactgg tattatgcaa acaggttggc aatatctagg taataagtgg tactacctcc
    19681 gttcctcagg agcaatggcc actggctggt atcaggaagg taccacttgg tattatttag
    19741 accacccaaa tggcgatatg aaaacaggtt ggcaaaacct tgggaacaaa tggtactatc
    19801 tccgttcatc aggagctatg gcaactggtt ggtatcaaga tggttcaact tggtactacc
    19861 taaatgcagg taatggagac atgaagacag gttggttcca ggtcaatggc aactggtact
    19921 atgcttatag ctcaggtgct ttggcagtga atacgaccgt agatggctat tctgtcaact
    19981 ataatggcga atgggttcgg taatgacagg gcgcttataa ttatattaga acactcgctt
    20041 aatcaaagaa gtgactttgt tgtacttgac ctgacgattg gggagattaa aagcatgtga
    20101 aatctacaca tgctttttcg ttagttatga gtgttgaact tgactaacca ttgacaaaag
    20161 ataagagcaa ttaaaataag atacaaaaat atcaatgcta actgcaccga aacgcccgat
    20221 gctatggata gggctaatag ggagagcagg gacggggcga gaatgtccac tgtgctcaga
    20281 gcagagccca ccgtccccat cttgtcactg gggatatggg caaagacagc tgcttgtagg
    20341 cgagggctga gaatgccgat aatcgtagaa ctgatgaaac tggtcatgaa aattacgata
    20401 taggcttgac aaaggatact agttattaga gtcaataggg aaatctcaca gaaaaccaag
    20461 aggtgcgtga aacggatatt tttaaataga ttactgctgg tcatattgcc aaggatagct
    20521 ccacaagaca tgatgatgga gagcagggcg aggagttgcc caatgctcag ttgtgctagt
    20581 gtctgttgga tgaagcggag ggcaatcagc cgaggggaca catccaagat ggcaatcata
    20641 ctggtcgtca gaaacagtag tatgacggta tcttttaacc tcaggagcac agccagcgac
    20701 tgtttaagat gttgaaaata tttcttaaaa ctcagtgctg tatgtgacat ttcaattctt
    20761 ttttcaacct catacaaggt atgtcgaata acatacaggc ccaaaaaggc aatgacaaaa
    20821 gtcagagtgt tgataaggga aatagtttga atacttataa cattgataag gaatgcgcca
    20881 gccagattgg cgacaatacg gacaaccctc atcagagact gcctgaaccc catggcatca
    20941 tgcaggtcgt ccttaattac actgatgtag agggcgttca tcatgtaggc agacaggtag
    21001 ctcaaggtgt cagagatgag gttgatgatg acaatcataa tgactgaaac taatgaaaag
    21061 ggcgacaaga cgagaaatac tgtcaaaata gcgtagagca ggattttgat tttggcaatc
    21121 cagagtgcgt gtttgactct attttcttga aaatctccta gaatcccgag aaagagttgc
    21181 gatagtaggg gaaccatctc tgaaatggaa atcagtaaaa tcgctagcgg agcgaaattg
    21241 tactgagcca cataattgat aatggcgagg tagaaaatac tgtcgccgaa tgatgaaaaa
    21301 cagctgttta gcagcaactg tctatatatg ttgtttgtcc aaaataattt catacttttc
    21361 tccttatgtc tgcacatcga atgggaattt attatttaat agacaccaat ataccccatg
    21421 cttcctattc cgaagtcaaa caaatctgct ttaccactat ctccttgaaa cataagtaaa
    21481 ccgtgatcat ctcgttcaga acatgctaaa attacctgtt ggattttttt catcagtaat
    21541 ttgttttgat tgtagacagt ggtttgtagt aagctagtta ttccgtggca atatcctgtc
    21601 atcattttta gatgatggtt aaaaacaaat tcttgatatt tactaataat atctttgttt
    21661 ccgtcacaat cgtacataca aagatataag attattccgg aaattccttt gcaccaagaa
    21721 agttgtaaat ttcctaaatt ttcagtatta gaagtaactt tttctaataa tttttttaat
    21781 tcagtatgga atgtatggag atcattatag aacatagaag gttctaagac tttagaatag
    21841 gcaaataaag catatgcaat tccacaatat ccatgagcaa agctatagtc taaaatgctt
    21901 tctttggctg tatctctttg taggaaataa tgataaattt cccctatact attgtggatg
    21961 aaaattttaa gagtattgtc attggtaaat tgatagtatt ttattaatga taataggaca
    22021 ccagattttc ccaatgcaaa gtctatttcc tctagagtat cataattctc tattaatttt
    22081 ttagcggtga cgtttgctaa ttgtagatag tattgatttt tactgataga aaataaatgt
    22141 aggaataacc atagatagcc tgcatcacca aatagcagtg agtattgata ttcatatgtg
    22201 tgtgtcgttc taattgtcac tgccttcttg atgatagaga gtattttaga atccagttct
    22261 ggggggtaca atttatttag aggaaacagt agtccagcta ttccgtgttg gaatgataaa
    22321 ttacttacga aatttccaaa ttctgttgaa gaagtgatcc ttccttcaga atttacagtt
    22381 ttatctagta aaaattgtag aacactatta cattctgttt tgtaatcata tttatgttcc
    22441 tctatttttt taattttgac taaattattt gtttgactta aatttagtag acattgtaac
    22501 caaaatagtt gctcatctgt gagctgacct tgagtatgtg atagttctag taattgaata
    22561 ggatccttta gttagattca atcaatctat aacacaacaa cataataata cttttaggat
    22621 aacttatcaa atattatagt aaaatgagat aataacagga taaatc
//
LOCUS       DAVLAQ010000029        22372 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000029 DAVLAQ010000000
VERSION     DAVLAQ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.029"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            11..964
                     /locus_tag="VXB71_001225"
     CDS             11..964
                     /locus_tag="VXB71_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0451340.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLQQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSSLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            1041..3029
                     /gene="uvrB"
                     /locus_tag="VXB71_001226"
     CDS             1041..3029
                     /gene="uvrB"
                     /locus_tag="VXB71_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0451341.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            3039..3602
                     /locus_tag="VXB71_001227"
     CDS             3039..3602
                     /locus_tag="VXB71_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451342.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            3568..4056
                     /locus_tag="VXB71_001228"
     CDS             3568..4056
                     /locus_tag="VXB71_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451343.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            4130..4597
                     /locus_tag="VXB71_001229"
     CDS             4130..4597
                     /locus_tag="VXB71_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0451344.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(4594..5109)
                     /locus_tag="VXB71_001230"
     CDS             complement(4594..5109)
                     /locus_tag="VXB71_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0451345.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5121..5648)
                     /locus_tag="VXB71_001231"
     CDS             complement(5121..5648)
                     /locus_tag="VXB71_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0451346.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(5926..6489)
                     /locus_tag="VXB71_001232"
     CDS             complement(5926..6489)
                     /locus_tag="VXB71_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0451347.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(6473..7024)
                     /gene="coaC"
                     /locus_tag="VXB71_001233"
     CDS             complement(6473..7024)
                     /gene="coaC"
                     /locus_tag="VXB71_001233"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0451348.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(7036..7725)
                     /gene="coaB"
                     /locus_tag="VXB71_001234"
     CDS             complement(7036..7725)
                     /gene="coaB"
                     /locus_tag="VXB71_001234"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0451349.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7955..9625
                     /locus_tag="VXB71_001235"
     CDS             7955..9625
                     /locus_tag="VXB71_001235"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0451350.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIYVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            complement(10116..11282)
                     /locus_tag="VXB71_001236"
     CDS             complement(10116..11282)
                     /locus_tag="VXB71_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0451351.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(11295..12119)
                     /locus_tag="VXB71_001237"
     CDS             complement(11295..12119)
                     /locus_tag="VXB71_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0451352.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            complement(12254..13468)
                     /gene="thiI"
                     /locus_tag="VXB71_001238"
     CDS             complement(12254..13468)
                     /gene="thiI"
                     /locus_tag="VXB71_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0451353.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(13477..14619)
                     /locus_tag="VXB71_001239"
     CDS             complement(13477..14619)
                     /locus_tag="VXB71_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0451354.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            14757..15185
                     /locus_tag="VXB71_001240"
     CDS             14757..15185
                     /locus_tag="VXB71_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451355.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            complement(15336..17561)
                     /locus_tag="VXB71_001241"
     CDS             complement(15336..17561)
                     /locus_tag="VXB71_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0451356.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17725..19677)
                     /locus_tag="VXB71_001242"
     CDS             complement(17725..19677)
                     /locus_tag="VXB71_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0451357.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(19674..20585)
                     /gene="pfkB"
                     /locus_tag="VXB71_001243"
     CDS             complement(19674..20585)
                     /gene="pfkB"
                     /locus_tag="VXB71_001243"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0451358.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(20582..21322)
                     /locus_tag="VXB71_001244"
     CDS             complement(20582..21322)
                     /locus_tag="VXB71_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0451359.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            21485..21572
                     /locus_tag="VXB71_001245"
     tRNA            21485..21572
                     /locus_tag="VXB71_001245"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21519..21521,aa:Ser,seq:gga)
     gene            complement(21755..22102)
                     /gene="ssrA"
                     /locus_tag="VXB71_001246"
     tmRNA           complement(21755..22102)
                     /gene="ssrA"
                     /locus_tag="VXB71_001246"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         6598 a         4587 c         4615 g         6572 t
ORIGIN      
        1 ggacggggat atgaagaaca aaagaatatt taaagacttc caagcttcaa aaatgagttt
       61 aaacatttac acaagcccct tgttagcctt tgtttttgtc ttcataggag agtttgtggc
      121 ttttactttg tatggtattg gcttgttagc tctcatcgga cttgctagaa attttggaga
      181 ggctggtcaa aatcttgcaa gctacttgca gaccttgcaa cagagcttga cggataaaac
      241 aagtgacttt cgtttaattt taggattact ggcctttggt tttattctta acactgtgtt
      301 cagatggaca agaaaagttg agaaaagacc tattcgaacc ttgggatttt atagagagaa
      361 tttcctcagc aatcttctga aaggatttag tctaggcttg gcactttttc ttctgacctt
      421 gttaggttta gtggtcttag gtcaatatcg tttggaatcc attcacttga atccttattc
      481 tcttgccttt gtcgtcttta ctatcccatt ttggatttta caggggacag cagaagaagt
      541 ggtggcccgt gcttggctac ttcctcaatt ggcctcaaga accaatctaa aactagctat
      601 tcttatatct agcctgttct ttaccctgct tcatatgggc aattctagcc tcacccctct
      661 atctctagta aatctctttt tattcggagt tgccatggct ctttatcttc tcaaaactga
      721 tacagtttgg ggtgttgcag gtattcatgg tgcttggaat tttgctcagg gtaatctctt
      781 tgggatttta gttagtggtc aaccgtcagg aacgtctctg atgacctttt taccacaagg
      841 caatcaagat tggctatcag gtggttcttt tggcatagaa ggttccatta tgacaagtct
      901 ggtattacta ctgctgattg tctatcttgc taataaatta aagaaagaaa atgaaaggat
      961 gtgacttcgg tccgtccttt tcttcgtgaa aatactataa gtatgctaaa ataggaatag
     1021 cacatggaga gaggattctt atgatcaatc acattacaga taatcaattt aaactagtat
     1081 caaaatatca accatcagga gatcaacccc aagctatcga gcagttggtg gataacattg
     1141 aggggggaga aaaagctcag attctgatgg gggcgactgg aacagggaag acctatacta
     1201 tgagtcaggt catttctaaa gtcaataaac caactctggt tattgcccac aataaaactc
     1261 tggctggtca gctctatggg gagtttaagg aatttttccc tgaaaatgca gttgagtatt
     1321 tcgtatccta ctatgattat taccagccag aggcctatgt cccttctagc gatacctata
     1381 ttgagaagga tagttctgtc aatgacgaga ttgacaagct tcgccactca gctacctcag
     1441 cccttttgga gcgtaatgat gttattgtcg tggcctcagt ctcttgtatc tatggtttgg
     1501 gttcgcccaa ggaatacgct gatagtgtcg ttagtctccg tcctggtcta gagatttctc
     1561 gtgataaact cttgaatgac ttggtcgata ttcagtttga acgtaatgat attgatttcc
     1621 aacgcggaag atttcgtgtt cgtggggatg tggtagagat tttcccagct tcccgagatg
     1681 aacatgcctt tcgagtagaa ttttttggag acgaaattga ccgtattcgt gaagttgagg
     1741 ctctgacagg tcaggtgttg ggagaagtgg atcatttagc gattttccca gcgacacact
     1801 ttgtgaccaa tgacgaccac atggaagttg ccattgcaaa gattcaggcc gagttggagg
     1861 agcagttagc tgtctttgaa aaggaaggta aactgcttga agcccagcgt ttgaaacagc
     1921 ggacagagta tgatatcgaa atgttgcgtg agatgggcta taccaatggg gttgaaaatt
     1981 attctcgcca catggatgga cggagcgaag gagagcctcc ttatacgctt ctcgacttct
     2041 tcccagatga tttcttgatt atgattgacg agagtcatat gaccataggg caaatcaagg
     2101 gcatgtacaa tggagaccgt tcgcgtaaag aaatgctggt taattatggt ttccgtttgc
     2161 cgtctgcttt ggacaatcgt cctctccgtc gggaggagtt tgagagtcac gttcatcaga
     2221 ttgtttacgt ttcagcgaca cctggtgact atgaaaatga acagaccgag acagtgattg
     2281 agcaaatcat tcgtccaacg ggactcttgg atccagaggt ggaagtccgt ccgactatgg
     2341 gacagattga tgacctcttg ggtgaaatca atgcccgcgt tgaaaaaaat gagcgtacct
     2401 ttatcacaac tttgaccaag aaaatggcag aggacttgac cgactacttc aaggaaatgg
     2461 gtatcaaggt caagtacatg cactcggata tcaagacctt ggaacggacg gagattatcc
     2521 gtgacctgcg cttgggtgtc tttgatgtct tggtcggaat taacctgctc cgtgaaggaa
     2581 ttgacgttcc tgaagtgagc ctcgtagcta ttctcgatgc tgacaaggaa ggtttccttc
     2641 gcaacgaacg tggactcatc cagactattg gacgtgctgc tcgtaacagt gaaggccatg
     2701 tcatcatgta tgcagacacg gttacccagt ctatgcaacg tgctatcgat gaaactgccc
     2761 gccgtcggaa aattcagatg gcctataatg aagagcatgg tatcgtacca cagacaatca
     2821 agaaagaaat ccgtgacctg attgccgtga ccaaggcagt tgctaaggaa gaggacaagg
     2881 aagtcgacat caatagcctc aacaaacaag agcgtaaaga actcgtcaag aaactagaaa
     2941 aacaaatgca agaagccgtc gaagtgcttg actttgaact ggcggctcag atccgtgata
     3001 tgatgttgga agtcaaggcc ttggattagg ggaatagtat gatttattta agaaagttaa
     3061 agagagaaga tttgatgtct ttatgggaaa tggcttattc acaacttaat ccagtttgga
     3121 aacagtatga tgctccctat tatgatgatt atcagtattt ttcaaatttt aaagaattcg
     3181 aactacaaaa atcagaatcc attttaagca actcaaatcg ccttggtatt tttgttgatg
     3241 ataaactagt tgggactgtt tcgcgttatt gggtatgtaa acaaacaaga tggatggaat
     3301 tgggaattgg tatttatgat aaaaaattct ggaacactgg tattgggaaa gttgctatgt
     3361 tgcagtggat agataggacg tttcaggatt acttggagtt ggagcatctg ggtttgacaa
     3421 cttggtcagg gaatcttggt atgatgaaac ttgctgaaaa attaagaatg aaaaaagaag
     3481 ctcatattcc aaaagttcgt tattatcaag gtaaatattt tgatagtatt aaatatggta
     3541 ttttgagaga agactgggag aaaataaatg acggttatta tcaaatcaat ggaaactcct
     3601 aaagagatag aaggtaaatc ccttgttcac tggcaaatgt ggagagaggc ttatgatgac
     3661 cttttgcctg cagaatttca ggagacaatg acattagaaa gatgtcgact ctttagtcaa
     3721 aagtatccag aaaatacatt gattgcgata ggtgatctga aggtagttgg ttttatcagt
     3781 tatggtaact ttcgtgatga gactatgcaa gctggtgaaa ttattgcttt atatgtttta
     3841 aaagactatt atggaaaagg tatcgcacaa aagttaatga aagcagcttt gactgctctt
     3901 aatcattttt ctgaaatttt cttatgggta ttgaaagata acaagcgcgc cattgctttc
     3961 tatcaaaaaa tgggttttac ttttgatgga caagaaaaaa tacttgaact tggaaagcct
     4021 ataaaggaaa aacgaatggt gttctattct aaataatttt aaaaaagtaa aagataatat
     4081 ctctggtagt aagtctgaaa atttaataaa ttagaaagcg agtaaattta tgtcccgttc
     4141 ccaattaaca attttaacaa atatctgtct gattgaagac ctcgaaactc agcgcgtggt
     4201 gatgcagtat cgcgcccctg aaaacaatcg ctggtctggt tatgcctttc ctggaggtca
     4261 tgtagaaaat gatgaggctt ttgcggagtc tgtcattcgt gaaatctacg aagaaacagg
     4321 gttgactatc caaaatcctc aacttgtcgg cattaaaaat tggccactag atacaggtgg
     4381 gcgctatatt gtcatttgtt ataaggcgac tgagttctct ggtagccttc ggtcttcaga
     4441 tgaaggagaa gtttcttggg tgcaaaaaga ccagattcca aacttggatc tggcctatga
     4501 tatgctacca ttgatggaaa tgatggaagc tcccgacaag tcagagtttt tctaccctcg
     4561 ccgtacagaa gacgattggg aaaagaaaat cttctagtct tttactaaat aacctagctg
     4621 atccaaggcc tcctcgatat agtggaggtc ttgttgtgtt tcggcttcga ctaggtggta
     4681 atggatgcca tctgtcaatt cagatagagg tctaaagtca gaatgctcga cttgttctag
     4741 aaaatgttgc acatctctgc gacaagacag tttaagcaag gtttcaattt ctccataaac
     4801 gggatggtca atcaaggtat tctggacatg cccaccatta tcgacaatag caaggagttc
     4861 ctgaccgatt tcttcaactt catgtttcac tttgaaaagt ttgtgaacat aaggattggt
     4921 atcaatttgc ttatagatgt agccacgatt ggtggatagg ataggagcgc catcggctct
     4981 caaaattgca atatcctgca caatgacctg acgtgtgaca tgaaaatgtt ccgccaaact
     5041 ttggccatta agggctttag gagcttcttt caagagttgg agcagggctt gtttgcgatc
     5101 ttttgtcata gcttttcctt ttaacggcgt tttcgaagca ctttatagac agctagtgct
     5161 aatgtatagt ctaccatact atggataatt gtgccaaatc caactagtac aaatagaaca
     5221 tagaacatat tttctacatt ggtacccgaa gttgcgtaaa aaaggacaca ggctaatact
     5281 tcagcaaggg catgaacaac agccaaaaca aaattgaaaa cccaggaaga ttttggttta
     5341 tctagggtat cggggaattt ttgtaggtaa agagctccta aagcaccaaa agatatatgg
     5401 gaaaaagccc gaaaaacgat aaccatggga tagccagcca tcaaaaatcc aaaactagag
     5461 gctaggatga caaaaactgc catcaagggc gacaagaaca tggctataaa aatagcgatg
     5521 tggctcccca aagtatagga agcaggtgga atgacaatct tgaaaggcat aacaattgga
     5581 atcaaaatcg caatagccgt taaaagggct gtcattgtca taaattgtgt ctttttccgt
     5641 gtattcacaa gaatctcctt tttaactgca tatacactag tatggtacaa taaaccagac
     5701 aataaagcaa gaatttactt gggtttatag atcatttttt agttaaaagt tatagtagat
     5761 ggaaactaga atagtccacc tctacttcta aaacattgtt agcgatttga ctgtcctgat
     5821 cgatttgtcc tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt
     5881 atagagcaaa atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt
     5941 ttgtagtcgt ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga
     6001 atttgttgag ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa
     6061 taggaagaag attcctccaa ggacaaagat agtatttgtc aaggaaccaa gggctccagc
     6121 taaaatcaga ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat
     6181 caaaatacgt gggacgatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg
     6241 agagaagagg tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc
     6301 catcaaaaat ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac
     6361 aggaatatga acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct
     6421 cagaaagtgt atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg
     6481 ttttttcatc gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc
     6541 ctcgtccgtg gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt
     6601 aggtttctaa tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca
     6661 tagcaggagc tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca
     6721 tgttgtccgc aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga
     6781 taaataaatc tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttcct
     6841 tcatgacatc caagtggaca ggattctgtg agagcacctg tagtgtcaaa ggttggataa
     6901 actctgtagc agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac
     6961 tgactaaatc tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg
     7021 ccatagtttt cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat
     7081 ttcttcttta gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg
     7141 atctgctgaa atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag
     7201 actttttcgt gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc
     7261 aatcagatga atagtgggat tccattcctt gactagggat atgattttgg gtgtcttttt
     7321 aaggaacaaa acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct
     7381 taaaaattct tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg
     7441 agtgtagtca gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg
     7501 catttctatt agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg
     7561 ctctggcttc agagctcgtt ttgtcgtaat taaacaaact tcatgccctg cagaaagcaa
     7621 agtctctgtg ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct
     7681 atcgatagct tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac
     7741 aaaaataagc ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta
     7801 tagtttcaaa ctataaagcc atataaaatt taagaaagga ctctaaaagc cttaaaaaca
     7861 gagatattta cgaacgttta gagagtttta ggatgttaaa aatcttgttt tgtgatataa
     7921 tgaattatca tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca
     7981 gagtattgag ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttatgacga
     8041 tttggagttg tacggaaagt acaaggctaa actcagcttt gataaaattc gtgcagttga
     8101 gagcaatcca gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga
     8161 aggaaagtcg acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac
     8221 catgattgct atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc
     8281 tggtggtggg tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga
     8341 tatgcatgct attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca
     8401 ccaagggaat gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt
     8461 gaacgaccgt gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc
     8521 acgtgaggat ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc
     8581 aacggacatc gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga
     8641 ccgtacgcct gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa
     8701 ggatgctatt aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg
     8761 tggtccattt gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct
     8821 tcacttggct gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa
     8881 attccttgat atcaagacac caaacttgcc aacatctcca gatgcagttg tcattgtcgc
     8941 aacccttcgt gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa
     9001 tgtagaggca gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa
     9061 gttcggtatt ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat
     9121 tgcagtctta aaagaactct gtgcctcaat ctatgtacca gttgaattgg ctagtgtctg
     9181 ggctgatgga gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga
     9241 aaatccagct aactataaac gtttgtacga taatgccctt tctgtccaag aaaagattga
     9301 aaaaattgtc actgaaatct atcgtggtag caaagtgaac tttgagaaga aagctcaaac
     9361 acaaattgct caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac
     9421 tcaatacagt ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac
     9481 cattcgtgaa ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt
     9541 tatgaccatg ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga
     9601 tggaactgta ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata
     9661 atatccaagc tcattttttc tcagactgca agcagttcat caataagatt tatactcttc
     9721 gaaaatctct tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt
     9781 cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt
     9841 gctctttgat tttcattgag tattaataga ctggtttggt atcctgaaaa ctatatcgta
     9901 taggtgtcgt catggatcct tttagctgat ttaaggatac gaaaacacaa tactatgact
     9961 aaattgaaat gttaaaattc aatttctagc cacctaatcc tgcttcaaat agttatcgaa
    10021 caagttttat gatagctacc ttgttaggat gctcttattt tttaccagac aaaacaaaag
    10081 gattaaggga gtgaatttcc ttaatccgat agttcttatt cttgacgttg tccgaaatca
    10141 gcaatcatct gatccatttc ttgtcgactc ggagttgtca gcatatacag gtaatctcct
    10201 tgaagttccg cgaaggcagc tggcatgact tttttaacct tgaactgctg gctatatttg
    10261 gcaagcaaat cctcttctga ataaacatag tgagcatttg cacggcgaga agtagccaaa
    10321 caatactgag tttcaaagtc tgacgccggg aactcctctc ctgcgacaat agctgcatag
    10381 ccacgataaa ggtccaagga atgagcaaag ttataaacat caatggtaaa accacctgca
    10441 gggcggttat tgtactcgat ggtaatataa tcgtccccct cacggaagaa ctcaatatgg
    10501 aaaaaccgtt ctttcatacc aaattctttg acaattgctt ccccatactt gcgcagttta
    10561 ggatccatat ccttgagcac ataataagaa ttgtccatct tataaatcat gaggtcaagc
    10621 ggtgtatagg cgtagtcaaa ggttgttgag aagacaatct ttccatcctt gtccacgagc
    10681 ccgtcaaagg tacagatttc gctggaagtg acaaattttt caaagaaata aagggttgaa
    10741 tggtcccatt cttgcttgaa gtgattgata tcgtcttctg tctcaagttt aaaggttgcg
    10801 gctgctccca ctccattatc aggtttggca atcattggaa gaccgatttc tttcactgct
    10861 tgatcaacat ctgcttccgt cttgataaca gctccaggta ccacaggaac acctgctttt
    10921 ttgaaaagtt tcttcatttc agacttatat ttcgtctttt tgagatcctc tggtttggca
    10981 ccaaaaacat tgaattgttc tctgagtgtt gcgtctagct caagccagta ttcattgtga
    11041 gactcgatgc ggtcaattgg accatgttta taaaagagaa aagcaactgc acgtttgact
    11101 tcatctatgt tctcaagatt atcaacacga aaatactcgg tcaagctatt gcgcaagggc
    11161 tcatccaatt gctcgtaaga ctcttgacca attcccaaga ctgtgatgcc tttattagct
    11221 agttcgatgg taaactgttg aaagttttgt ggatagtagg gagaaataac aaggtaattc
    11281 ataggtaact ccttttataa atagagatta ccgaggaaat aaggcatttg tttacgccac
    11341 cattcccagt cgtgggcgac atcatgtccc cattcagcaa accaggctgg aatttgtttc
    11401 tggtcaaagg cttctttgag cttgtaaaag gatggtaaac catcttgttc ccaggctcca
    11461 agccccgtac acagcacaat ctctgcctga cggtaacggt caataaacca gccatcgttt
    11521 tggttccaaa tataatctac tggcgagttt tggtaaatag catcatcgtt gtagtaatcg
    11581 ccgacaaaga aacgtgcgtc gtaaacacca ctgagagcaa tcactttggt aaagacatct
    11641 ggatgctgga ggaagaaatt gagtgcatga taggctccca tagagcaacc tgtcgtcatc
    11701 atgccatcaa accaacctgt tttgtgcttg ataaaaggct tgaccacctc catgacaaac
    11761 tcagcatact ccacaccctt accaccaaac tgctgctctg ggataggaga ttcttggaac
    11821 ttccaagccg catactcatt catccgcccc ataccatcat tgtcaatagc aacgacaatc
    11881 atgcgactga tatccggatt tcgtttgata gctgggataa tcttccatga atgtccaatg
    11941 aaagactctt tgctattaaa aacattttgc ccgtcatgaa agtatacaac aggataggaa
    12001 cggtctgtat ctttctcata atctttagga agaagaatac gtacacggcg ctccttacct
    12061 gtataaggaa ccttgagttt gtgttctttc atttttagat aaaagtagga ttgattcatt
    12121 gtcagaaaac tctctatatt caaaatttta tatcattata tcataaaaat aaaaaaagtt
    12181 agttttttac ctgtttttag agaaaaaact aacttttttt actgattttc gctattcttt
    12241 tggattttct gaattagagc agattgtcaa tcaagtcatc aacttcatct ttttcggctt
    12301 gaggtgtgat ttcagtaatc atgattccag ccactgctcg ctcaaccaag ccttcaacat
    12361 ccatacgcgc ttcgtactgc tccgcattct taattttagg atttgttttt ggacgatctg
    12421 gtgcaaaaat agtacaacag tcttcaaacg gttggattga aatgtcaaag gtatcgattt
    12481 cctgggcgat gtcaatgatt tccaacttgt ccatggtaac cacaggacga atgatgggag
    12541 tgttggtaac agcattgata gccttcatac tttcaagggt ttggctggct acttgaccta
    12601 gactttcccc attgatgata actaaaccat ttcgtacctc acgaatacgg tcagtaatac
    12661 gcatcataaa acgacgcgtc aaggtcataa ggtaggcttc tggcgctttg gctttgattt
    12721 cctcttgaat ctctgtaaaa ggaacttcga taaactggat atttccccca aatttggtta
    12781 atttacgggt caaatcttgg gcttttttaa gagcaccagg actcgtgtaa ggtgggctgg
    12841 caaagtgaac tgcctctata tctacccctc gtttaagcgc tagatagcca gctacagggg
    12901 aatcgattcc ccctgacaac atgagcatgc ccttaccaga agttcccact ggtaatccac
    12961 ctgcccctcg aacggtttca taagaaagat aggctgcttc ttcacgtatc tccacctgaa
    13021 gattgatgtc aggacttttc atttgagctt gtacgtttgg aatggcttcg aatacagccc
    13081 ctccaagcgt ttggttgagt tcacgactgt ccaattcaaa ggtgtggtcg ctacgcttgc
    13141 tagagatttt aaaggtcatg ccttccttgt agatgtcctg cataatctct tggacagcag
    13201 acttcagaac ttctacagat ttttcaacct tataaacagg ggaaaagttt tgaattccaa
    13261 atacttgttt gagcgattct gctactgctg tgtaatctgc tccattgagg taagcgtggg
    13321 cacggtcgcg atctgctgtt accttaactt ggggatagat agacaaaacg tctgaaatat
    13381 tattgcgaag tttattgatg aaacgcatac gatttttgcc cttggttgac agctcaccgt
    13441 agcgaatcat aatttctgaa tactgcatga atgctcctat cttacttttc tagtttgatt
    13501 gtaaattaat tttagcttgg tcaagaactg ctcgacctga ctcatatcat tttcaaggtc
    13561 tagactaaga cgcacagctg actgagcctt atccttgtcc actcccatag caatcagggt
    13621 tccggctggt ttcccagcct tggacgaaca agccgaggtc gttgagatga aaatatcata
    13681 gtcttcaaag gcgtgaacaa tgacctcacc acgaacaccc ttgattccaa aagtcagaat
    13741 atgaggggcg aagtcttcct catctgaaaa gacaaatata tccggatagt ccagaagtgc
    13801 ttgacgaatc actgccttca tctgcccagt cttgctccta aagatatcta gcttttccat
    13861 agataaacgg agagccttag cggtcgctgc aattcctgcc acattttcag ttgtcgaacg
    13921 gtaatcacgt tcctgaccac cacctgttaa aagaggcgta atcttcttgc cagacttgat
    13981 atagataaaa ccaacaccac ggattccgtg gaacttgtga ccagagaaag tcgcgaaatc
    14041 cactcgttct gtcagatact tttcagtcgg aatcttggca agcgcctgaa ccgcatcaac
    14101 gtggaaggaa atagttggct tgtctgccaa gaattctgaa atagcctcaa taggttggat
    14161 agagccgatt tcattgttca cagccatgat ggaaacgagg gtcgtatcag gtcttatcaa
    14221 atcttctagc gcctcaacat ccacaaatcc tttgttatca actggagcaa aatccacttc
    14281 aaaaccttga gctttcaacc agagggctga ttccttaact gctggatgtt caatggctga
    14341 tacgatgatg tgcttgccaa actgggcttt ttcaaatgct actcccttga tgatccagtt
    14401 atccccttct gtcccaccag atgtaaagaa gatttcatca cttttcttac cgattaaatc
    14461 tgcaatctgt tgacgggaag catctaaaat tcgtgttgcc tggtctccca aacgatggag
    14521 actagatgga tttcctaaaa tttttgaagc cacctgcata taggtttcaa gggcttctgg
    14581 atagggcctg gtcgtcgccg aattatcaaa gtaaatcatg tttctcacgc tttctaaaat
    14641 cactccttct attgtatcat gaaacggagc ctgcgacaag aaagggcaat ttctcttttt
    14701 ttaagatttt tttaaagaaa cagagtataa taaatcataa tcaaaggaga gaatgtatgt
    14761 ctaactatcg tagaacttca aaaccgaaaa cagaacatat caaaaaaggc tttactgttt
    14821 ttcaaaaaac cattactact atcggtagta tccttggttt gattaccgcg ggtatcacga
    14881 tcatgaacgc cttggataat aataataaaa atactaaaaa agaacctacg acaagccaga
    14941 cgacaacctt tgtcaaagaa attcaaaaag aatcccctca ggaaaatact actccaaata
    15001 aggaaaataa cacttctcaa gaaaaaacac aacaagaaga aacgccaaaa tctagcgtca
    15061 aggaagagaa aaaagaagat cagaaaacag caactcagga ctctactaca cctgctacaa
    15121 gtaaacctgc cactgaaaat gaaaaacagc ccaatactcc aacttcagaa aataatactc
    15181 aatgaaaatc aaagagcaaa ctaggaagct agccgtagac agtacttgag tacggcaagg
    15241 cgaagctgac gtggtttgaa gagatttgcg aagagtataa aagtaatcaa tagccagtaa
    15301 aatagctcct tccaaccttg gaaagaagct attttttatt gctgcaatac ttttcttggc
    15361 ttggtacctt cagctggacc aatgacacct gccatctcaa gctcttccat gagacgggtc
    15421 gcacggttaa atccaactga caaacgacgc tgaatcatgg atgcactggc tttctgtgtt
    15481 tcgataacca aagacttagc ttcttcaaaa agcggatcac caccagcatc tccatccgaa
    15541 aattctcctt cattttcaga aacctcacct ggatcaaaac tctcatcgta gtctgcatct
    15601 gcctgagtct tgatgaagtt cacaatgcgc tcaacatcgt catccgagat aaaggagcct
    15661 tggagacgaa ctggatgatt ttcatcaatc ggtttaaaga gcatgtctcc tcgaccaaga
    15721 agtttttctg ctccattttc atccaaaatc gtacgggagt ctgttcctga tgaaaccgca
    15781 aatgctacac gagatggaac attggcctta atcaaaccag agatgacatc aacagatgga
    15841 cgctgagttg caagaatcat gtggatacct gcagcacgcg ccttctgccc aagacggatg
    15901 atagcatctt ccacttcctt gctggccacc atcatgaggt cagccaactc atccacaatc
    15961 acgacaatga atggtagcgg aatttgcttg tactcagact gggaattgaa ctcttctacc
    16021 ttggcattaa aacctgcaat attccgaact cccaccttgg caaagagttc ataacggttt
    16081 tccatttcat ccacaacctt ttgcagagcc ttgctggctt tgcgtggatt ggtcacgact
    16141 ggaatcaaga ggtggggaat atcattgtaa acagataact caaccatctt gggatcgacc
    16201 atcataaatt taacttgatc tggtctcgcc ttcatgagaa tgctagcaat aatgccgtta
    16261 actgctactg acttccctga acccgttgaa cctgcaacta gcaagtgggg cattttagaa
    16321 aggtcaaaag ctcttgcggt tccattaaca gccttcccta aaggaatttc caagaaattt
    16381 tctgctttcg tttgcgattg ttcccatagt tctcggaaag atacagtggc aatatcggag
    16441 ttgggcactt caattccgat tagggatttc ccagggattg gtgcttcaat ccggacatct
    16501 ttggcagcca aggctagagc gaggtcatct gatagattgg aaatgcggtt gacccttaca
    16561 ccaacagccg gcttgacttc atacttggtc actgatggcc caatttcggc ccgttcaact
    16621 gttaccttaa taccaaagct agcaaaggtt gcttctaaga ttttgatatt ttctctgaca
    16681 attttcttct ctttagactg atcttttggt ttatctggtg caaagagttg taagcttgga
    16741 agtttgtatt caagggcttc tttggctgaa aaatcgacct gaacatcttc gtcatctgag
    16801 tcatcttcct gttcagggaa tttaagttca gcttgaggca ggatgatttc tggttccacc
    16861 cacttttctt ctggaatagg tggaagattt tgaacagctt cctctgtcag aatttcaccc
    16921 gtttccatat caacaggagg caaatcgagt aaggcttttt cagtctcttc ttgttctaat
    16981 ctagcctctt tctcagcctt ttggcgagct ttttcttctt gtttgacaaa gcgttcctct
    17041 tttcgacgct cgtgcccttc ccaccatttg gcaaagcctc tactgaaaaa ttcagcaata
    17101 tcgtaaacag accaagggct gactaggaga gaacccacta aaatcaagat agaaccaata
    17161 aagtaagttc cgatatttga aaagagaaaa gctgttggaa tataaagagc gaccccgatc
    17221 aagccccctc cagcaaaact agtcgttcga aaaccagtca gatctgtcac aacctgagcc
    17281 atggtccctt ttagaacgga cttgtccaaa ccatatttcc aaaccaagta ggcttcaaaa
    17341 atcaagagta agccagcaaa tatggtgaaa aagccagata agagtccttc ctgttttcgt
    17401 atccacttga aaaaaaagag atagattaat aggccgaata tcgccagata agctaggcta
    17461 cccactagca agcgaattaa attataaagg gttatacctg cagcccctaa tttgaaggct
    17521 gcgaaaatca ataaaatcgc aattcctaac gaaatcaaca ttcgttgaat cgcttctttt
    17581 ctttccagtt ctgctttaga cggtctccgt cttgttgtac ttgtattctt gtttgccatt
    17641 cttctattat accatatttc acaggcattt cggaaagaga aaaagactgc accaaacggt
    17701 ccaatctttt catttttcta ttttttatgc ttgtggtttg cgtaggtaac cataaaccac
    17761 accacttacg attgctccta ccaagacaga aacgaggtaa aggagagcat ttgaagtaag
    17821 ggcgataacg aagattcctc cgtgtggcgc catgagttta ataccagtaa gaccaacgag
    17881 tccacctgct actgctgaac caaggatgaa gcttggaatc gcacgagctg ggtcagcggc
    17941 accaaatgga atcgctccct cagtgataaa tgacaagccc atgatgatgt ttgtcaaacc
    18001 agagttacgt tcttccttag taaatttatc tttgaaaaga agagttgcga caaagattgc
    18061 aagtggtggc accattcctc cagccataac tgctgccatg gctacagaac cacctgaaga
    18121 aacagttgct gcaagcgtac ctgtaccaaa gacataagct gctttattaa ctggtccacc
    18181 catgtcaaca gccatcattc caccaaggac gataccaaga aggacagctg aacctcctcc
    18241 aagaccgcct aggaagtcat tcatagcagt gttgattgct gccattggga tattcacagc
    18301 tagcataaca aatcctgtca agattgttcc aagaagtggc aatagaagga ttgatttagc
    18361 accttcgagt gaacgaggaa ctttaacgta tttcttgatg gcaagaacca aggcacctgc
    18421 gataaatcca ccaacaaggg cacctaggaa accagatgag acacctgcaa gagttgaagt
    18481 tgcttcacca cctgcggcat aaggaatttt accaaaggca aaaccttctt tggcaatagc
    18541 accagccacg aaacctgcta ccaaacctgg tttttcagca atagagtagg caacataacc
    18601 cgcaaagact ggaagcatca aaccaaaggc agctccacca attttcatga acatagaagc
    18661 taactcatgg taagaaccaa gattgccaag gttttcattt ggaacaccca aagcaccgtc
    18721 aatcaagaag gcaagggcaa tcatgatacc accaccgata acgaatggta acatttgaga
    18781 tacaccactc atcaagtgtt tgtagaaggc accaccaagg ctttgttttt cgttagaggc
    18841 tgttgcagct tttgcaccat tagcggcacg gtagacttca gtatctcctg aaagagccaa
    18901 gttaattagc tcttctgtct tacggatacc gtcagcaact ggacgattga tcaatggttt
    18961 tccatcaaat cgatccattt caacggcctt gtctgctgca atgataatag ctttagcctt
    19021 acggatatct tctgcagtta gttgatttcc aacaccgcta gcaccgttgg tttcgacctt
    19081 gataccaacc cccatttcag cagctacttt ttgaagggct tcttgggcca tgtaagtgtg
    19141 ggcaatacct gttgtacaag ctgtaacagc tacgataaag tcaccagagt cattagcagg
    19201 tacttgaaca agttcctcag ttttttctga agcttggtca aaaagttcga taacttggtc
    19261 tgcagatgtt gcttgacgaa gtttgtctgc aaaaccgtct ttcatcaagt attgagacaa
    19321 ttctgccaag gctgccaagt gagtatcatt ggcaccttct ggagctgcaa tcatgaagaa
    19381 gaggtcagtt gcttgtccat ccaagctctc gtagtcaaca cccttatttg acttagcaaa
    19441 tagaactgtc gcttctttga cagcagcgtt tttgctgtga ggcattgcga ttccatcacc
    19501 caaaccagta gaagtcaaag cttcacgcgc caaaattcct tctttaaatg tttcaaaatc
    19561 tgttacataa ctgtgctctg tcaaattttt aatcatctcg tcgatgacag ctgttttttc
    19621 agttgcctgc aaatctagca acatgacatc ttttctcaat aggtcttgaa ttttcatctt
    19681 ttttctacct caacttttcc atatgtttct ttaataaatt ccgccgttgc caagtcatct
    19741 gagaaggtag ttgccgttcc gcaagccact ccccatttga aggcttctac tgcgtctttt
    19801 gatttgacaa attcacctgt gaatccagca accatagaat caccagctcc aactgaattt
    19861 ttgactgttc ctttgattgg tttagcgaag taagctccct cagatgtgac aagaagggcg
    19921 ccatcaccag ccatagagat aataacattt tgagcaccct tagccagtaa ctcacgagcg
    19981 tatttctcaa tttcatctaa actttcgagt ttaaccccaa aaatcgctcc aagttcatga
    20041 ttgtttggtt ttacaagaag aggctggtag tccaaactat caattaaggt ctgtccttca
    20101 aagtcacaga ccacttgcgc accagtctgg cgcgtcaagg aaatcaaatc cttatagata
    20161 acattgccta gatttttagc acttgaacct gcaaagacaa ctgtatcttc tgctgtcaga
    20221 ctagataaaa tagctttcaa ttcttctagc tgaaccggtt caacagttgg acccgttccg
    20281 ttgatttctg tttcttggtc tgctttgatt ttaacattga tacgagtatc ttctgccacc
    20341 tggacaaaac gtgtctcgat ttcttcctct gctaaagtat ctgtgataaa tttaccagta
    20401 aagccaccga taaatcccgt cgctgtattt ggtatattca aacgtttcaa gacacggctg
    20461 acattgattc ctttcccacc agcaaactta tcatcactgt ccatacgatt tacactacca
    20521 actttgactt ggtccaaacg aacgatatag tcaatggatg gattgagtgt gactgtataa
    20581 atcatacttc tattacctcc gttttctcct taataacctg caagagctca tgcccttgac
    20641 tagtgataac gatagcgcgt ttgagtggtg ctaccttggc aaagcaagtt tgtccaattt
    20701 ttgacgaatc caccaagacg taggtctgct tggcattctc caaaatagct cttttcacag
    20761 ctccttcctc catatcagga gtcgtataat agccatcgtc aacaccattc attccgataa
    20821 aggcacggtc aaagtgcaat tggttaatct ggttaagagc aacgcccccg atactagcat
    20881 ctgtcgccgt cttgacgttt cctccaacca tgacagttgg aatctgcttt tcaaccaact
    20941 gagcggcatg gtgaatggag ttggtcacaa ctgtaacatt cttattgacc aattcatgaa
    21001 tcaaaaaagc agttgttgtt ccagcatcga taaagatgac atctttttct ttaatgagag
    21061 aggctgcttt ctgagccagc aacttctttt cttgaaggtt tttgacagat ttttcttgaa
    21121 tggtttcttc ttcctgtaag gagtggggga gttctgctcc accatgcaca cgacgaagct
    21181 tgttttccgc ttccaactca tccaagtctc ttcgaaccgt tgattctgac gtttctagca
    21241 aactaactaa tttttctaga gaaactacat gatgttgatt taactcctct aaaattagtt
    21301 gtttacgttc tgtttttaac actgaatcac ctcctgttat cgtttacact attcattcta
    21361 tcatactttc tttcgaagtc aagcattttt tatcattttc tttcaaaatc tatcattttt
    21421 tcttatttct agaattttta ttgcaagata agagccttta tggtagacta tttgagtaag
    21481 tattggaaga ttactcaaga ggcttaagag gccgtgttgg aaacgcggta ggcgtgtaat
    21541 agcgtgcgtg ggttcgaatc ccatgtcttc cgtcgaaaaa agattatttc taggatgcga
    21601 caaatgttgt atcctttttt ctatcctttt tttaaaatag ggtctgtttg tgactccctt
    21661 tttagcaaaa gaatgcaaag gaataccaaa gataaaaata aaaaacgttg atttaacaac
    21721 gttttaccaa ggaatgcaaa agaatgcaaa ggaataatgg agccggtggg agtcgaaccc
    21781 acgtccaaac acctgccaac atatttgtct acaaccatag gttatgtatt attttaacaa
    21841 cccctcgaca cataactcaa gtctagaaac tgcgagtcta tcaatctctt atcaagccgc
    21901 tagacaaggc ttaatcgtat ctcgctaata ataagacctg tcattgaaca cgagcaatcc
    21961 aaatcgggtc acgcctgctg gtttttaggc agctagagcg taagaagtgt tattttttgc
    22021 agttatattt aactgagcgt ttacgtcgcc acacgagtcg caaaatatgc ctcataatgc
    22081 ctgtcgaatc cgtaacgacc ccaaaagaca ataaaaccat tataccttat ctaactcaaa
    22141 aatgcaaaaa gaaatcacat acctaaaaaa gatactattc gagaaattta gcaaactgga
    22201 agactaacta caactttctc agtgcataac tttacgattg taaatagagc ttacgaaatc
    22261 caattaacac atacctaaga tgaagctatc tgttttgaag aaattcacga agagaattat
    22321 tctaaaatac tttcagatga gaattttcgt actctcttta ttttaattca tt
//
LOCUS       DAVLAQ010000030        22266 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000030 DAVLAQ010000000
VERSION     DAVLAQ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.030"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..1200
                     /locus_tag="VXB71_001247"
     CDS             <1..1200
                     /locus_tag="VXB71_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0451360.1"
                     /translation="LSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEI
                     QDAYKKFQEKTNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNY
                     IFFSKNRLAIQNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAY
                     SHEYFIVIDDPISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDI
                     FLKEIMESCKEEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPT
                     SESFVGNAMRKILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGE
                     SHFKDPVKTLSIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQ
                     WKCEILE"
     gene            1373..2671
                     /gene="purB"
                     /locus_tag="VXB71_001248"
     CDS             1373..2671
                     /gene="purB"
                     /locus_tag="VXB71_001248"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0451361.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(2726..6664)
                     /gene="strH"
                     /locus_tag="VXB71_001249"
     CDS             complement(2726..6664)
                     /gene="strH"
                     /locus_tag="VXB71_001249"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0451362.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(6979..7695)
                     /locus_tag="VXB71_001250"
     CDS             complement(6979..7695)
                     /locus_tag="VXB71_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0451363.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            8043..9830
                     /locus_tag="VXB71_001251"
     CDS             8043..9830
                     /locus_tag="VXB71_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0451364.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            9827..10303
                     /locus_tag="VXB71_001252"
     CDS             9827..10303
                     /locus_tag="VXB71_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0451365.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            10331..11236
                     /locus_tag="VXB71_001253"
     CDS             10331..11236
                     /locus_tag="VXB71_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0451366.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            11223..12038
                     /locus_tag="VXB71_001254"
     CDS             11223..12038
                     /locus_tag="VXB71_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0451367.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALTLSALGHFALGM"
     gene            12045..12449
                     /locus_tag="VXB71_001255"
     CDS             12045..12449
                     /locus_tag="VXB71_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0451368.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            12747..13913
                     /locus_tag="VXB71_001256"
     CDS             12747..13913
                     /locus_tag="VXB71_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0451369.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKKLVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALDCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            14029..15066
                     /locus_tag="VXB71_001257"
     CDS             14029..15066
                     /locus_tag="VXB71_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0451370.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            15273..16127
                     /locus_tag="VXB71_001258"
     CDS             15273..16127
                     /locus_tag="VXB71_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0451371.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            16277..16534
                     /locus_tag="VXB71_001259"
     CDS             16277..16534
                     /locus_tag="VXB71_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0451372.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADLVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(16576..16893)
                     /locus_tag="VXB71_001260"
     CDS             complement(16576..16893)
                     /locus_tag="VXB71_001260"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451373.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSNHIYGKVKLTWFEEI
                     FEEYKSPHNKTHTIKVFMYCPPKVRQKKSNFWGQYISIPDTMRFFNFKDFLQLLLTHI
                     KLF"
     gene            complement(16965..17243)
                     /locus_tag="VXB71_001261"
     CDS             complement(16965..17243)
                     /locus_tag="VXB71_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0451374.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNA"
     gene            17465..18229
                     /locus_tag="VXB71_001262"
     CDS             17465..18229
                     /locus_tag="VXB71_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0451375.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            18794..20173
                     /locus_tag="VXB71_001263"
     CDS             18794..20173
                     /locus_tag="VXB71_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0451376.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            20187..20852
                     /locus_tag="VXB71_001264"
     CDS             20187..20852
                     /locus_tag="VXB71_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0451377.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            20966..21061
                     /locus_tag="VXB71_001265"
                     /pseudo
     CDS             20966..21061
                     /locus_tag="VXB71_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            21252..21791
                     /locus_tag="VXB71_001266"
     CDS             21252..21791
                     /locus_tag="VXB71_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0451378.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            21858..>22266
                     /locus_tag="VXB71_001267"
     CDS             21858..>22266
                     /locus_tag="VXB71_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0451379.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
BASE COUNT         6154 a         4146 c         4973 g         6993 t
ORIGIN      
        1 ttaagtcaag cagagcatga tattgaaaaa attaaccaag caattatcaa acataattca
       61 gaaatctcgg gtattcaaaa gttaaaagta gatctccttc aaataaataa tgaattagct
      121 ttttatgaaa ttcaagatgc atacaaaaag tttcaagaga aaacaaataa aaaagcaatt
      181 tgtgaaaata attataataa cagtagtaaa cgagtaaagg attatgagaa gcagatttct
      241 gatttagaag acaagaaact taatatagat attgcagttg atgaaattaa taaaagttta
      301 aattacatat ttttttcaaa aaatcggtta gctatacaga atcaaaacgg aaaatactat
      361 ctgttatcaa gaggtaagtc tgtggtcccc agtagggttt ccgtagggga acgaaatgcg
      421 ctggcattat gttatttctt tactgagata attcaacaga gagagttagc agatgcttat
      481 agtcatgaat attttattgt tattgacgat ccaatttcta gttttgatat ggaaaataaa
      541 gttggaataa cctcgtattt aaaatattgt ttaactagat tttttaaggg gaatagtaat
      601 actagagttt tactaatgac ccatgataaa caaacaatat atgactttga tatctttttg
      661 aaagagataa tggaatcctg taaagaagag gaaggtggac aaaaatctaa atacaagaag
      721 ttagaattgg tttctggtaa attacaagaa ttcaaaacta gtactcacga ttatacagaa
      781 ctacttgaaa tagtcttcgg ttatgcattg ggaaatagta cacctacttc ggaaagtttt
      841 gttgggaatg caatgagaaa aattttagaa gcctatggta gttttaatta taagaaggga
      901 attgccgagc taacaacaga tcctttaatt gttgaaaaaa ttgataaaga atacagaact
      961 tattttgaga atcttatgta tagactggtt ttaaacggtg aaagtcattt taaggatccg
     1021 gttaaaactt tgagtattga tttctttgat accatttctg atgaagaacg aaaaaaaaca
     1081 gctagagatt tactagtttt gctttatctt ttagatgatt tacatgtttt aaaacattta
     1141 gagggtgtat caaatgcgga aaatagactt gaacaatgga agtgtgagat tttagaataa
     1201 gagaatcata ccatttgact tattgcaatg gttgaagttt gcatgatagc tgattagagt
     1261 aatcaaagga ttattacttc ctaattttat tttctacaaa ccctaattta gcatctaata
     1321 atgcaaagtt tcctgagcct catagataaa aaagattttt aaggagaaaa acatgatcaa
     1381 ccgttactct cgccctgaga tggcgaatat ttggagtgaa gaaaataaat accgtgcttg
     1441 gcttgaggtg gaaatcctct ctgacgaggc atgggctgag ttgggggaaa tccctaagga
     1501 agatgtggct ttgattcgca agaaggcgga ctttgacatc gaccgtattt tggaaattga
     1561 gcaggagacg cgccacgatg tggtggcttt cacgcgtgcg gtttctgaga ctcttggtga
     1621 agagcgcaag tgggttcact atgggttaac ttctaccgac gtggtggata ctgcctatgg
     1681 ttacctctac aagcaggcca acgacatcat ccgtcgtgac cttgaaaact tcactaatat
     1741 catcgctgac aaggccaagg agcacaagtt caccatcatg atggggcgta ctcatggtgt
     1801 gcacgctgag ccgacaactt ttggtcttaa attggcaact tggtatagcg aaatgaaacg
     1861 caatatcgag cgcttcgagc atgcggctgc tggtgtagaa gctggtaaga tttctggtgc
     1921 ggttgggaac tttgccaata tcccaccatt tgtagaggag tatgtctgcg ataaacttgg
     1981 catccgtgcc caagaaatct ctacacaagt ccttcctcgt gaccttcacg ctgagtactt
     2041 tgcggttctt gccagcattg cgacttcaat cgaacgtatg gcgactgaga ttcgtggtct
     2101 acaaaaatct gagcaacgcg aagtagaaga gttctttgct aaagggcaaa aagggtcttc
     2161 agcaatgcct cacaaacgca acccaatcgg ttctgaaaat atgactggtc tggcgcgtgt
     2221 cattcgtggt cacatgatta cggcttatga aaacgtcgct ctctggcacg aacgcgatat
     2281 ttctcactca tcagctgagc gtatcatcac accagatacg accattttga ttgactacat
     2341 gctcaaccgt tttggaaata tcgtcaagaa cttgacagtc ttcccagaaa atatgatccg
     2401 aaacatgaac tcgacttttg gtcttatctt tagccaacgg gctatgttga cattgattga
     2461 aaaaggcatg acccgtgagc aagcctatga cttggtgcaa ccaaaaacag cctactcttg
     2521 ggacaaccaa gtagacttta aaccacttct tgaggcagat tcagaagtaa catcacgtct
     2581 cacacaagaa gaaatcaatg aaatcttcaa cccaatttat tacaccaaac gagtggatga
     2641 tatctttgaa cgtcttggac taggtgatta attaaaaaat aaacagcgag cttcaatctc
     2701 gctgtttatt ttttatcgaa aagacttagt cttcttttct tttagtgagt ccataggctg
     2761 ctagtgtgga catgagtcct gcgactacta gtcctgcaga atcgtgagtt cctgtttcag
     2821 gaagtttttt ctctgttacc acaggagctg gatcttgagg aagagctttg ctttcctcag
     2881 caggagcagt tgatggagct ggttggcttg ggatttctag tcttggtttt tcttcagcaa
     2941 tagcggcttg tccgttttca tcgcctacat gtgttaccat agttccgact tcgactattt
     3001 gagtaacggc ttcctgtgct acgacactat ttacaagtgt tttcacttcc ttaccatcgg
     3061 cagaagtgct cacagagtag aagttgctac gatgtccatt gacgccctta gtaatgactt
     3121 gtgtttttcc tttgagtaag agtggatttt cacgagtcac tgtggtaaat ggaatttctt
     3181 ctttttggat atccagtcta ggttttacct cagtagttgg tgcaagacca ctttcatcac
     3241 ccttgtgagt tacaggagcg ccaacttcaa ccacttggtt tataacttct ttggttacct
     3301 ggctatcaag gactgtttct gttgtttttc cattttcagt gagtacagag atgtaatgag
     3361 ttcgttcacc tttgactcct gctgtgataa tattttcctg accagctggg aggttaggat
     3421 tttctttctt gataacttca aatggaattt cttcagttct tgtgatgagt tctggtctgg
     3481 tttcaacatt ggcagccact tcattttcat ccaggcttcc tgaatgagtt gcagctggtt
     3541 tgaggccttg aagagcggct tttaggttgg ctacaagtgt gtcaagctca gcttgtttat
     3601 tacggttgag gttgtaattt agagctgttt tagctgcgtc aagggcctca agactttctt
     3661 tactatatcc ttctaagttt gtaggaattt tagctaattc ttcgcggaga gcattataat
     3721 tagcacggaa gtagtctttg ttgtggtctg caaaggcagt catgagttca aagatttcct
     3781 cttccttgta ctcagcgctt ggtctatctg cccagattga aagcatactt ccgactgttg
     3841 gaagatctac ttcaggatat ttggtagaag ctagttgatt gaatggaact ttaccagaat
     3901 tttcaactgc ttttgaaaga gggtaagctt catcttgttt gtgattgcct ataacataat
     3961 accagtcacc gttggtattc aagaatttat agcctttgct tgctaggtat tgaggtgatg
     4021 cgaggttata tccccaccag cctttagacc agtaagaaat caagacatct ttgtcaaact
     4081 gaacatcgtc cttgtcttca tagtagaagc catcgttgaa ggccattggt tgaagccctc
     4141 tttctttggc catagctgcg agggtgttgg catattcggc aaatttgcca tagagttgat
     4201 accacttgag gtagtaccag ccttgggcac tagtcgcatc gttggcgtat tcgtcagtac
     4261 caaagttgaa aatctttgtt ttacctgcaa agaagtccat gtatttaccg atgagggctt
     4321 ttacaaagtt catcgcttct tcgtttttca agtccatagt tgtttttgaa actttatcaa
     4381 agtgggcttg aggattttta atacctaatt tttccatggc aaccagcata gcatccatgt
     4441 gacctggact gttaatagct gggatgagac caatgtcctt agatttagcg tattcaatta
     4501 gctctgtcac ttctgcctgt gttagtgcag taccgtttgg atcgtcgtag taagctttag
     4561 ttccttcgat aatagctttt ttaacgtcat cactagcata ggtttttccg ttggcagtaa
     4621 tggtcatatc attgagtaga aagcgaagtc cgtcatttcc tagaaggaga tggacatcag
     4681 aatatccgag ctcactggcc ttgtctacga tgcgtttgag ctggtccaga gtaaagtatt
     4741 tgcgtccagc atcgattgag attaccttgt ttttggcaag tttttcaacc tcacgtttag
     4801 cttcttcttc tttttgagct tcaggcgtga gggtcaagtt gttgacagtt tcttgaagtt
     4861 tagcaatggc ttgatcaatc gtatcttgtt gggcacggct aaggttgcta tcgagagagc
     4921 gaatagcttt ttcagcttct tttacggccg tgacgctttc tgcagtataa cggttcaggt
     4981 cttttggtac ctcgttaagt gcttgctctg cagattcata atcagctgcg aagtattcag
     5041 cgttggcatt tgcaaaatga cgcatgagtt tgaagaggcg tgatggtgaa taacgtgcag
     5101 atggagtgtc agcccaagca gctaccatac caccgatgat tgggatatca gctccttctg
     5161 tttttggtac agaagtgatt ggtgtgtttt taataccatt gagcccctga tcgagattgt
     5221 accagccttg gccatcagcg tttcgtccaa gaacgtagta ccaagcatca ttggtattaa
     5281 ggatttggtg acctttttca gctagtagtt tagaagaagc gacatcgtag cctccccaac
     5341 caccagtcca catagaaacg atgatgtctt tgtcaaaact accaaagctt gtgtcgctat
     5401 tgtagtagat accgtcgtta aaggccattg gtttgagacc gtgcgatttt acaatacgag
     5461 cgaggtcatt ggcgtaggca ataaattttt catagccttt tacagggtag ccttcgtttg
     5521 gatagtattt atcagcttga agcacactcc aacctttagc atctgtcgca tcattggcat
     5581 attcatcaag tccgatgttg aagatttcag tctttttcgc gaaataagca gcatacttgt
     5641 cgataagggc ttttgtaaaa gcgacagctt gttcgttgtc aagatcgaca gtacgggctg
     5701 atttcttccc aaaatagcta aagttagggt tttggattcc caattctttc atggcattga
     5761 gaatcgcatc catgtgtcca ggactattta ctgtcggaat gagaccgata cctttatctt
     5821 tggcatagtt aatcagatct gtcatttgac tttctgttaa gtgattgccg tttggatcgt
     5881 tgtaataatc atttgtacct ttttcaatgg cgcgtttgac atcgtcactg gcataggtct
     5941 tgccgttagc tgtgatgctc atatcgtcca acatgaaacg gagtccatca tttccgacta
     6001 ataggtgtaa atcagtgtag ccataatgtt tcgctttatc gatgatttcc ttgagctgtt
     6061 ctggtgagaa atatttacgt ccagcatcaa tagaaacaat tttctttttc gctagttttt
     6121 catttacagt tgcagcacgt tcctttcctg tctctgtttc cggtttgtca gcctctgctt
     6181 tcgcttcatc ttttttagct ggtttatcct tgtcagtctt gtctgtattt gactctttag
     6241 aatcaacctc tttcgcttct tcctttttag ggctagcttc ttcttccttt ttattagcag
     6301 tttctttttc agcagaagtt ggagttacca cctctgcttt atcactagga gttgaactaa
     6361 cttcctcttg tggtttttct tctgtttttg gaagactagc taccttatca gtagctggag
     6421 tttctgtttc tacagttttt ggagcttctg gttgaagctc tgctttaggt gtttcctcag
     6481 tccgattttc ggatgattga ggggaatcag aaaccgtatg gatggtcggt tggttttctg
     6541 tagtagtagg agtaactcca tcggctgcaa cagtctgtgc ttggaaggca aatccaatta
     6601 gaacagaagc tgctcctaca gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt
     6661 tcattgcaaa acctcctgat tgcattgtta tattgatagc gattatataa atcaacgcct
     6721 ttattttatt tcttatatta acgagagtca agaggagatg acaaaaaact ataataagta
     6781 taaaaaaata taaaatttaa acttaagatt tcagattggt cgaaaaaata catatatata
     6841 tctagtataa tttttggttc tatttctata aaatattcca caaattatag aatcttccaa
     6901 aaataggtaa gcgctacctt tttggtgtgg tataataagc atagaaaaag cccgagcgat
     6961 taggctcagg ctttcttctt agtgatcacg gtcacatgag atgaatttaa tcttgtagta
     7021 atcagatcgt ttgtaagttt cactgtattc taaaacttgg ccagttgatt cgagtttggt
     7081 gattttagtt tgtaggacag tagggaattg ttcatcgact ccgaggactg aagccgcatg
     7141 ttctggagtt ggaaagacta tttcgttgat ttcttcaaag tgttcatcat tcatgtgaat
     7201 gtggtagtct aacttgaaac gattatagat agaactatag tattcaaggt ttggataatt
     7261 tgcgttgata tattgttctg ggatgtagga tgtatggtag atataaacga caccgtttga
     7321 ttcgcggata cgttcaatct tgtagtagaa ttgatcgccg cgtagaccca atttttccaa
     7381 gtaaacaagc ttgtttccgc gttcaattga aagaacagtt accttatcat ctttagcatt
     7441 gaagagttca atatctgaaa actctacaag cttgtgtttg cgtgcacgtg aaacgaaggt
     7501 tccttttcct tgttggcgga caatatagcc atctttggca aggtcgttta aggcgcgaac
     7561 aactgtgata gagctgacat cgtacattga aatgagttct gcttcagtgt aaaatttatc
     7621 tccactgcta aactgcccag agatgatttt attttttaat tcgtctttta tgtattgata
     7681 tttgggaatt gccatatttt tacctctatt ttccttctcc atagaaaatt ttaccataaa
     7741 agcgaaaaaa atagtagtct tttgaataaa aaattagaat aatagtttga aaaattaagc
     7801 gatataggga ttgctcatat tttatcaatg cattctatac aaaattattt taggtcctat
     7861 attccgaatt taaagagcgt ttgaaatggg tctaaaaatg tttgaaacta attgaatgtg
     7921 tgtataatag taaaaatgca gtaaatatcc cgacaatttc tattgacaat tcaaacagat
     7981 tggtttataa ttaatataac aacaaatgaa agcgcaaact ttcgcggtcg gaaggtagtt
     8041 ttatgacacg atttgagata cgagatgatt tctatctcga tggaaaatca tttaagattt
     8101 tatctggtgc cattcattat tttaggattc ctccagagga ttggtatcat tcgctctata
     8161 acttgaaggc tcttggtttt aatacggtag agacttatgt tgcttggaat ttacacgagc
     8221 ctcgtgaagg tgagtttcat tttgaaggtg atctggattt agagaaattt ctccaaatag
     8281 cgcaggattt gggtctctac gcaattgtgc gtccgtctcc atttatctgt gcggaatggg
     8341 aattcggtgg cttaccagct tggctcttga ccaagaacat gcgaattcgc tcatccgacc
     8401 cagcatatat cgaggcagtt ggtcgctact atgatcagtt attgccaaga ctggtgcctc
     8461 gtttgttgaa caatggtggc aatattctca tgatgcaggt tgaaaatgag tatggttctt
     8521 acggagaaga taaggcttac ctgagagcga ttcgacagct aatggaagag tgtggcgtaa
     8581 cctgtcccct ctttacatca gatggtccat ggcgagctac tctgaaagct ggaaccttaa
     8641 ttgaagagga cctctttgta acaggaaact ttggttctaa ggcaccttac aacttttcgc
     8701 agatgcagga attctttgat gaacatggta agaaatggcc actcatgtgt atggagttct
     8761 gggatggttg gttcaatcgc tggaaagaac cgattatcac acgggatcct aaggaattgg
     8821 cagatgcagt tcgagaggtt ttggaacaag gctctatcaa tctttacatg ttccacggtg
     8881 gtacaaactt tggtttcatg aatggttgct cagctcgagg aactttggac ctgccacaag
     8941 ttacatctta tgattacgat gcccttctgg atgaagaagg aaatccaact gctaaatatc
     9001 ttgcagtcaa gaagatgatg gcaacacatt tttcagagta tccgcagttg gaaccactct
     9061 acaaagagag tatggagttg gatgctattc cactagttga aaaagtttct ttgtttgaaa
     9121 ccttagatag cttgtcaagt cctgtagaaa gtctctatcc tcaaaagatg gaggagctgg
     9181 gacaaagtta tggctaccta ctttatcgaa cagaaacaaa ctgggatgca gaagaagaaa
     9241 gacttcgtat cattgatggt cgagataggg cccagctgta tgtcgatggt cagtgggtta
     9301 aaactcaata tcagacagag attggggaag atatttttta tcaaggtaaa aagaaagggc
     9361 tatctaggtt agatatcttg atagaaaata tggggcgtgt caactatggg cataagttct
     9421 tagcggatac gcaacgtaag ggaattcgga caggggtctg taaggatctg catttcttac
     9481 taaactggaa acactatcca ctcccactag acaatcctga gaaaattgat ttttcaaaag
     9541 gatggactca aggacaacca gccttttacg cttatgactt tacagtcgaa gagccaaaag
     9601 atacttacct agacttgtct gagtttggta agggagttgc ctttgtcaat gggcagaatc
     9661 taggacgttt ttggaacgtt ggcccaactc tctcacttta tatccctcat agctatctca
     9721 aggaaggtgc caaccgtatc attatctttg aaacagaagg tcaatataaa gaagagattc
     9781 atttaactcg taaacctaca ctaaaacata taaaggggga aaacttatga caattgtagg
     9841 atgccgtatt gatggacgtt tgatccacgg acaagtagcc aatctttggg ctggaaaact
     9901 aaatgtttca cgcattatgg ttgtagacga cgaagttgtc aacaacgata ttgaaaagag
     9961 tggtttgaaa cttgcgacac caccaggtgt gaaattgagt attttgccag ttgagaaagc
    10021 tgcagccaat attcttgctg gtaaatacga tagccaacgt ctctttatcg tggctcgtaa
    10081 accagaccgc ttccttggtt tggtagaagc aggtgtacca cttgaaaccc ttaatgttgg
    10141 gaatatgtct caaacaccag aaactcgttc tattacacgt tctatcaacg tagtagacaa
    10201 ggatgtggaa gacttccaca aactggcaga aaaaggtgtt aaacttactg ctcagatggt
    10261 tccaaatgat ccaatttcag actttttgag cttattaaaa taggaaaaaa atttttagga
    10321 ggtcattgtt atgatacaat ggtggcaaat tttacttctc actttgtact cagcttatca
    10381 aatctgtgat gagttgacga tcgtttcatc tgcaggttcc cctgtatttg ctggtttcat
    10441 tactggttta atcatgggag atgtgactac tggtttactt atcggtggta acttgcaact
    10501 gttcgttctt ggggttggta ccttcggtgg tgcttctcgt atcgacgcaa cttctggtgc
    10561 ggttcttgcg acagccttct ctgtttcaca aggaattgat gcaccgcttg ccattactac
    10621 aatcgctgta ccagtagcag ctctcttgac ttacttcgac gttcttggtc gtatgactac
    10681 taccttcttc gctcaccgtg tggatgctgc aatcgaacgc tttgactata aaggtattga
    10741 acgcaactac ttgcttggtg cgattccgtg ggctctatct cgtgcccttc cagtcttctt
    10801 tgcccttgct tttggtggtg cctttgtaca atcagtagta gacttcgttg aagcctacaa
    10861 atgggttgca gatggcttga cacttgcagg acgtatgctt ccaggtcttg gatttgcaat
    10921 cttgcttcgt taccttccag ttaaacgtaa ccttcactac cttgctatgg gatttggttt
    10981 gacagctatg ttgactgttc tttactcata tgtaacaggt cttggtggcg ctgttgctgg
    11041 tatcgtaggt actcttcctg ctgaagttgc tgaaaaaatt ggtttcgtga acaacttcaa
    11101 aggtttgtct atgattggta tttctatcgt aggtattttc cttgcagtgc ttcacttcaa
    11161 aaatagccaa aaagtagctg tagcagcacc ttctacacca tcagaaagtg gggaaatcga
    11221 agatgacgaa ttctaattac aaacttacaa aagaagattt taatcaaatc aacaaacgta
    11281 gcttgtttac tttccaatta ggttggaact acgaacgtat gcaagcttct ggttaccttt
    11341 acatgatctt gcctcagttg cgtaaaatgt atggtgatgg aactcctgaa ttgaaagaaa
    11401 tgatgaaagt tcatactcaa ttcttcaata cttcaccatt cttccatacc attatcgctg
    11461 gttttgacct tgccatggaa gaaaaagatg gtgtaggttc aaaagacgct gttaacggta
    11521 tcaagacagg tttgatggga ccattcgctc ctcttgggga tacaatcttt ggttcacttg
    11581 tacctgctat catggggtca gtcgcagcaa ctatggctat cgctggccaa ccttggggga
    11641 tcttcctttg gattgcagtt gcagtagcgt atgacatctt ccgttggaaa cagttggaat
    11701 ttgcttacaa agaaggggtt aaccttatca acaacatgca aagtaccttg acagctttga
    11761 ttgacgctgc atctgtactt ggtgtcttca tgatgggtgc tcttgtagca acagtgatta
    11821 actttgaaat ttcttacaag ttgccaatcg gtgaaaagat gattgatttc caagacatct
    11881 tgaaccaaat cttcccacgt ttgcttccag caatctttac tgcctttatc ttctggttgc
    11941 ttggtaagaa aggtatgaac tctactaaag ctatcggtat tattatcgta cttgctttga
    12001 ctctttctgc ccttggtcac tttgcacttg gaatgtaatt ccttatgact aaatcattaa
    12061 ttttggtgag ccatggtcgc ttctgtgagg agcttagagg tagcacagaa atgattatgg
    12121 gcccacaaga caacatttac acagtagctc ttcttccaga agatggccca gaagaattta
    12181 ctgctaaatt tgaagctgtt attggaggat tggatgattt cctagtcttt gcggatcttc
    12241 tcggtgggac accttgtaat gtggtgagtc gcttgatcat ggaaggtcgt gatattgacc
    12301 tttacgcagg gatgaatctt ccaatggtga ttgaatttat caatgcgagc cttacaggcg
    12361 cagatgcgga ctacaagagc cgtgctgcag aaagcattgt gaaagttaat gacctgttag
    12421 cgggcttcga tgatgacgaa gatgaataat actcttcgaa aatctcttca aactacgtca
    12481 acgtcgcctt gccgtaggta tatgttactg acttcgtcag tcttatccgg caacctcaaa
    12541 acggtgtttt gagctgactt cgtcagttct atctgcaacc tcaaagtagt gctttgagca
    12601 gcctgcggct agtttcctac agattttagt tggaactcga ttcaattcat gtgacaacgt
    12661 gaaaatcgtt agagcatttt atatagaata tacatgggaa tggagcttac tcccattccc
    12721 atatttaata gaaaaagagg aactcaatgc tacattatac aaaagaagac ttgctcgaat
    12781 tgggtgcaga aatcactacg cgtgaaatct accaacaacc tgatgtatgg agagaagctt
    12841 ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt cctacaagaa atcgctgata
    12901 aacatgacta tattaaggtt atcttgacag gtgctgggac ttctgcttat gtgggagaca
    12961 ccttgctacc ttactttaag gaagtctatg acgaacgcaa atggaatttc aatgctattg
    13021 cgacaacaga tatcgttgcc aatccagcaa cctatttgaa aaaagatgtg gcaactgtcc
    13081 ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt ggcgactgtt gatttggcca
    13141 aatccttggt ggatgagctt tatcaagtga cgattacttg tgcagcagat ggtaaattgg
    13201 ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt gcaaccagct gtctctaatg
    13261 atgctggatt tgccatgact tctagcttta cgtctatgat gttgacagct ctcttggtct
    13321 ttgatcctac agaatttgct gttaagtctg aacgttttga agttgtatct agtcttgccc
    13381 gtaaagtttt agacaaggca gaagatgtca aaaagctcgt tgatttagac tttaaccgtg
    13441 tcatctatct aggcgctggt cctttctttg gacttgctca tgaagctcag ctcaagattt
    13501 tggaattaac tgctggtcaa gttgcgacca tgtatgaaag cccagttggc ttccgtcacg
    13561 gtccaaaatc tcttatcaac gacaatacag ttgttttggt ctttggtaca acgacagact
    13621 acactcgtaa gtacgacttg gacttggttc gtgaagttgc tggtgaccag attgctcgtc
    13681 gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa tgtcaaagaa gtggcccttg
    13741 attgtggcgg tgtcttgaat gatatttacc gtgtcttccc ttacatcgtt tatgcccaac
    13801 tctttgccct attgacttca ctcaaggtag aaaataaacc agatacaccg tctcctacag
    13861 gtacagtaaa ccgtgtagta caaggtgtca taattcacga atatcaaaag taagacagtg
    13921 tttatgaatt cttgacaaga ggatttgtaa attatcagat aaaccataga ttgtcagtac
    13981 gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg agaacagaat gaaagcatac
    14041 acagagcgtg tatttggaaa tgttgagggc gaggatgtct tggcctatcg atttgagaca
    14101 gacggtggct accaacttga ggttatgact tatggcgcga ccatcttgcg ctatgtcgca
    14161 cctgacaagg ctggaaattt tgccaatgtt atcttgggat ttgatgactt tgatagttat
    14221 gtaggcaata gtcccaagca tggagcaagt gtaggtcctg tagcgggtcg tattgcaggt
    14281 gcgacctttg agctcaatgg taagacctat gaccttgagg ttaataatgc tagcaactgt
    14341 aatcacagtg gttcaactgg ttgggattcc agcttgtttg aagttgaaga agtaagcgat
    14401 catggcttga ctctctacac agagcgtaca gatgggacag gagggttccc tggaaatctc
    14461 aagatttgga tcagttatca cttggaagaa actggtgcct atgaaatcag ctacaaggta
    14521 acgaccgatc aggatacgct ggtcaatcca accaaccaca gctatttcaa cttgtctggt
    14581 gatttcacgc agacgattga ccgtcatgtc ttccaactaa acacagaggg catttactca
    14641 atcgctcctg acggtgttcc tgccaaaact ccagaagcca accgtgatgt ggtcaaacac
    14701 atctacaatg gtgccttgtt gaaggatatc tttgcagaag aagatgagca aatccagctg
    14761 gcatcaggtt tggatcatcc atttgccctt cctgcaggcc atgacaatgc tggattcctt
    14821 tatgaccaaa attcaggtcg cttcctgctt ttcaagacag aagctccttg ctttgtggtc
    14881 tacacagcaa actttgtgga tgaaagtgtc atcataggag gtcagccaat gctacagcac
    14941 aatgggattg ctcttgaagc gcaagcttta ccagatgcca ttcacagtga ccttaaaggc
    15001 caagtcattc ttaaagctgg tcaaaccttc accagtaaga cacgttatga acttgttgtg
    15061 aaataaaaaa gctggtcaaa aagtctttaa aattaaaata acgcatattg tcaggtgatg
    15121 aaaagtttga taatatgcgt tttattatga aatgatttac tttatattat cctgaaatgg
    15181 tgttattttt gagttatctg gcttgacttt cttgatggaa attatataat agttgcaaca
    15241 ataataatta caacgaaaaa agaggaccat ttatgaccta tgaatacaag agtcacattt
    15301 atttggcaga gacagtttta aatgtaaagg atttggccag tcaaacagcc ttttatcagc
    15361 aagttatcgg tttagaaatc ttatctcaaa ctgagacaga gtccattcta ggccttggtg
    15421 gaaaagtctt ggtacagctg attcaagcac aagagagcgg agaagtgagg gaacattatg
    15481 gtctttacca tttggccatt ctcttgccca cacgcaaggc tttggctgat gtcttgaaac
    15541 acctgacaga tttacagatt cctcttgtcg gcggtgcaga ccatggttac agtgaagcta
    15601 tttacttgga agatttggag ggaaatggca ttgaactcta tcgagataag ccagtttcca
    15661 catgggatat tcgagaagat ggacgcatta tcggagtgac ggaggctctt gcggcgcagg
    15721 acatttatga gttgggggaa agagtagagc cctttatcct ggcagaaggt acgagaatgg
    15781 ggcatattca tctttcagtc aaggatagtc gaaagtccag ccagttttat caaaaggtgt
    15841 tagggctaga ggataaattc agtgtgccta gcgctagttg gattgcggct ggagattacc
    15901 atcatcattt agcagttaac gaatggggag gaaaaggtct ggcttcgcgt aagcaaggct
    15961 taccaggttt agcctactat gtcatcgaag tcgcacataa aaaagaactg ttaacgattg
    16021 cccaacgagc acaagaagtt gacgcaccaa tcaaatggat gacatcgagc caattggaaa
    16081 tcacagactc agatggcatc gtgacccgta ttcgtttagc aaggtaaaat taggaatttt
    16141 taataagtta taagtattgc tagtttgctt tttgaacggt ctttggtaac agaactgcgt
    16201 gagctggatg ggtgagaatt ttgacaaaga agctgattag agatataatg aagaaaagtc
    16261 gagcaaggaa aaagaaatga caaattcaaa gtatattact tgtttgaaac gttcagaggg
    16321 ccagttgtgt gggattcaaa agatgattga aggagatcgt gactgtgctg atcttgtgac
    16381 gcaactgaca gcagtgagat ctagtgtaga gcgcgtgatt gagatgataa ttaccgaaaa
    16441 tcttactgaa tgtatcaatc agccactaga tgattctgaa gctcaaaagg aacgcttaga
    16501 aaaggctatc cgatacttga ttaaacggaa ataaatgaat gttttgagac gatatgtgca
    16561 aaggtctatt aactattaga atagtttaat gtgagtcaaa agaagttgta aaaaatcttt
    16621 aaaattaaaa aaacgcatag tatcaggtat tgaaatgtac tgcccccaaa agttagattt
    16681 tttctgtcta acttttgggg ggcagtacat aaaaaccttg atagtatgcg ttttattgtg
    16741 gggagattta tactcttcga aaatctcttc aaaccacgtc agcttcacct tgccgtagat
    16801 atggttactg acttcgtcag ttctatccac aaccttaaaa cagtgttttg agcagcctgc
    16861 ggctaacttc ctagtttgca ctttaatttt cattgagtat tacttcatct tctcatgaaa
    16921 ttgagttttt gcccagctcc tcttgattat tctacttgac cgggctaagc attcatacca
    16981 ccttctacgt tggtaacggt gaggccttgg gagctgagaa attggcaggt agatgcagag
    17041 cggactcctc cttgacaaat aacatagtat tcatggtcag gtttgagttc tttgtagcct
    17101 tgctctaagg tacttaatgg aagatttttg gcacctggtg catgtcctgc ttggaattca
    17161 tgtgcttcac ggacatcgat aagttctaga ttttcatttt gatattttcc ataaaagtca
    17221 gccatgctga tactagtttc catattctac tccttctggg ttagccattt tgtatagtga
    17281 ataagcgccg tcaaggtttt ggacggtaaa tcctgcttgc ttgaggatag gctctgcgat
    17341 atagctgcgc aaactactgt ggcaactgac gatgtaggct tgtttttctc ctcagttcat
    17401 cagcttcctc cttgacactc ggtcagattt tgatacaata gtacaaaatt agaggaggtg
    17461 ggctatgatt cagaaacatg cgattcccat tttagagttt gatgataatc ctcaggcggt
    17521 tatcatgccc aatcacgagg ggttggattt gcagttgcca aagaagtgtg tctatgcttt
    17581 tttaggtgag gagattgacc gctatgcgag ggaagtaggg gcgaactgtg ttggcgaatt
    17641 cgtttctgct accaagacct atccagtcta tgtcatcaac tacaagggtg aggaggtctg
    17701 tctggctcag gctcctgttg gctccgctcc agcagcccag tttatggatt ggttgattgg
    17761 ctatggtgtg gagcagatta tctctactgg gacctgtggt gtcctagctg atatagagga
    17821 aaatgccttt ctagtccctg ttcgcgcttt gcgagatgag ggagccagtt accactatgt
    17881 ggcaccttgt cgttatatgg aaatgcagcc agaggctatt gctgctattg aggaagtttt
    17941 ggaagacaga gggattcctt atgaagaagt catgacctgg acgacagacg gtttttaccg
    18001 agaaacggct gaaaaggtgg cttatcgtaa ggaagaaggc tgtgctgttg tggagatgga
    18061 gtgttctgct cttgctgcag tagctcaatt gcgtggggtt ctctggggtg aattgttgtt
    18121 cacagcagat tctctagcgg acttggacca gtacgacagt cgtgactggg gctcggaagc
    18181 ttttaataag gcgctagaac tgagtttagc aagtgttcac cacctttagt tgtactggca
    18241 aaggatttgt tttatcataa aatgtctagc tcatactttt caaaaatatg tttaaacgag
    18301 gtcaccttcc tcttgtccta ggcatgttga ggttgggaaa aatctttaaa atcagaaaaa
    18361 cgtatcatat caggtgatga aaattttgat actatgcgtt ttatgttggt aagatttaga
    18421 gtgagatgaa atgatactct tcgaaaatct cttcaaacca ggtcagcttc accttgccgt
    18481 atagatgtta ctgacttcgt cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
    18541 tgtgactagc tttctaatcg atgccttggt tttcattgcc tataatcaaa aagagaaatt
    18601 ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc ttttttgacc
    18661 tatagtcata tctatcaagt attgttcttg cctaagctat caataaaaag gtggcatttt
    18721 ttaggcttgg tgttagtgaa ttttgcctta tcctatctaa gtcatttcga gctttttatg
    18781 gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag gcttatctcg
    18841 tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac taggctctct
    18901 tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt ttgatcatct
    18961 tttcactgct gtctctgcag tctgtgtgac aggtctctca acccttccag tagctcacac
    19021 ctataatatc tggggccaaa taatctgttt gctcttgatt cagatcggtg gtctagggct
    19081 catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc ttcgtagccg
    19141 tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa agtttgtcta
    19201 ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc ttagttttcg
    19261 ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc tagcgatctc
    19321 agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg cttttcagac
    19381 cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc ttggttttat
    19441 ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca
    19501 tacgaagctt gtattattat tgactatagg tttgttgtta tttggaacgg caactactct
    19561 ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg ataaggtttt
    19621 agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga tagattatac
    19681 tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag gtggggcacc
    19741 tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg tctttgcacg
    19801 aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg cgccgcgaac
    19861 ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga taggattgat
    19921 tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcatat ttgaaaccat
    19981 ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg ggaaattggc
    20041 tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga ccttgtttgt
    20101 tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga aagcagatat
    20161 tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt ttgggcttgg
    20221 gaatttttgg gagcagtgtc ctagctgccc tagccaagca ggatatgaat attatcgcta
    20281 ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt ggagtgattg
    20341 gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc gataccgttg
    20401 tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt
    20461 tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa
    20521 agattggagc tgactcggtt atctcgccag agtatgaaat ggggcagtct ctagcacaga
    20581 ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg
    20641 agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac ctccgtggca
    20701 aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg gatgttgaat
    20761 ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc aacaaccagt
    20821 atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt ttttgatgct
    20881 taagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt caaaggctgg
    20941 actttatggt aaaatagaag gaagtgacaa gagagagtaa tactcaatga aaatcaaaga
    21001 tcaaactagg aaactagctg cgggctgctc aaaacactgt tttgaggttg tggatagaac
    21061 tgacgaagtc agctcaaaac actgttttga ggttgcagat agaactgacg aagtcagctc
    21121 aaaacactgt tttgaggttg cagatagaac tgacgaagtc agtaacatct atacggcaag
    21181 gcgacgttga cgcggtttga agagattttc gaagagtata agaaaaaatc agtcccctaa
    21241 aggagcagat tatgaagtta ttgtctatcg ccatttctag ctataatgca gcagcctatc
    21301 ttcattactg tgtggagtcg ctagtgattg gtggtgagca agttgggatt ttgattatca
    21361 atgacgggtc tcaggatcag actcaggaaa tcgctgagtg tttagctagc aagtatccta
    21421 atatcgttag agccatctat caggaaaata aaggccatgg cggtgcggtc aatcgtggct
    21481 tggcagaggc ttctgggcgc tattttaaag tagttgacag tgatgactgg gtggatcctc
    21541 gtgcctactt gaaaattctt gaaaccttgc aggaatttga gagcaagggt caagaggtgg
    21601 atgtctttgt gaccaatttt gtctatgaaa aggaaggtca gtcttgtaag aagagtatga
    21661 gttacgattc agtcttgcct gttcggcaga tttttggctg ggaccaggtc ggaaatttct
    21721 ccaaaggcca gtatatcatg atgcactcgc tgatttatcg gacagatttg ttgcgtgcta
    21781 gccagttcta attgcctgaa catacttttt atgtcgataa tctctttgtc tttacgcccc
    21841 ttcagcaggt caagaccatg tactatctgc ctgtcgattt ctatcgttat ttgattgggc
    21901 gtgaggacca gtctgtcaat gagcaagtga tgattaagtg cattgaccag caactcaagg
    21961 tcaatcgact cttggtagac caactttatt tgtcccaagt gagtcatccc aaaatgcgag
    22021 aatatctgct gaatcatatt gaaatcacga cggtgatttc cagtaccctg ctcaaccgat
    22081 ctggaacagc ggagcatctg gcaaaaaaac gccaattgtg gacctatatt cagcagaaaa
    22141 atccagaagt ctttcaggct attcgtaaga ccatgttgag ccgtttgacc aaacattctg
    22201 tcttgccaga tcgcaaactg tccaatgtcg tctatcaaat caccaaatct gtttatggat
    22261 ttaatt
//
LOCUS       DAVLAQ010000031        19811 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000031 DAVLAQ010000000
VERSION     DAVLAQ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.031"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            359..1522
                     /locus_tag="VXB71_001268"
     CDS             359..1522
                     /locus_tag="VXB71_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0451380.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1519..2196
                     /locus_tag="VXB71_001269"
     CDS             1519..2196
                     /locus_tag="VXB71_001269"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0451381.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2186..3040
                     /locus_tag="VXB71_001270"
     CDS             2186..3040
                     /locus_tag="VXB71_001270"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0451382.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALENVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3059..4126
                     /locus_tag="VXB71_001271"
     CDS             3059..4126
                     /locus_tag="VXB71_001271"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0451383.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            4136..5302
                     /gene="aroC"
                     /locus_tag="VXB71_001272"
     CDS             4136..5302
                     /gene="aroC"
                     /locus_tag="VXB71_001272"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0451384.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5312..6415
                     /locus_tag="VXB71_001273"
     CDS             5312..6415
                     /locus_tag="VXB71_001273"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0451385.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6426..6764
                     /locus_tag="VXB71_001274"
     CDS             6426..6764
                     /locus_tag="VXB71_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0451386.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6856..8139
                     /gene="aroA"
                     /locus_tag="VXB71_001275"
     CDS             6856..8139
                     /gene="aroA"
                     /locus_tag="VXB71_001275"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0451387.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8132..8608
                     /locus_tag="VXB71_001276"
     CDS             8132..8608
                     /locus_tag="VXB71_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0451388.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8605..9453
                     /gene="pheA"
                     /locus_tag="VXB71_001277"
     CDS             8605..9453
                     /gene="pheA"
                     /locus_tag="VXB71_001277"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0451389.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9450..10724
                     /gene="psr"
                     /locus_tag="VXB71_001278"
     CDS             9450..10724
                     /gene="psr"
                     /locus_tag="VXB71_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0451390.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11003..11848
                     /locus_tag="VXB71_001279"
     CDS             11003..11848
                     /locus_tag="VXB71_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0451391.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11838..12941
                     /locus_tag="VXB71_001280"
     CDS             11838..12941
                     /locus_tag="VXB71_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0451392.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12943..13929
                     /locus_tag="VXB71_001281"
     CDS             12943..13929
                     /locus_tag="VXB71_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0451393.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13945..15378
                     /locus_tag="VXB71_001282"
     CDS             13945..15378
                     /locus_tag="VXB71_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0451394.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15407..16441
                     /locus_tag="VXB71_001283"
     CDS             15407..16441
                     /locus_tag="VXB71_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0451395.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16641..17378
                     /gene="mecA"
                     /locus_tag="VXB71_001284"
     CDS             16641..17378
                     /gene="mecA"
                     /locus_tag="VXB71_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0451396.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17529..18815
                     /locus_tag="VXB71_001285"
     CDS             17529..18815
                     /locus_tag="VXB71_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0451397.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18817..19686
                     /locus_tag="VXB71_001286"
     CDS             18817..19686
                     /locus_tag="VXB71_001286"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0451398.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
BASE COUNT         5893 a         3605 c         4515 g         5798 t
ORIGIN      
        1 gtaacaaaag gcttctctat aaaatcaaat tttccagata cctactgaag ctgatttatt
       61 tcttcatctt tcttctacta cctttgtcac taaatttgac agacacatat tgctgataca
      121 acctctctac ctataatctc acggttaacc tgaggctagt ttcatagttt gctatttgat
      181 tttcgttgat aaaaagaaat gctcctccaa gacggaagag cattttttat tgtgattctt
      241 acacatttat ttcctagttt tgcaggaagt ctagtatacc attttttaaa agaagagtaa
      301 aaaagcaagg gtagtttctt ttttgagaat tgtctaaaag tttgatataa tggtagttat
      361 gaatagaata agagtcagca aaagggttga aaagaagctt gctaaggggc tagttttact
      421 agaagccagt gatcttgaga atgtcaatct taaggatcag gaagtagagg tgcagggtca
      481 ggaaggaaac tttcttggga ctgcctacct ttctcagcaa aacaagggct tgggctggtt
      541 tgtcagcaaa gacaaggtgg ccttcaatca aactttcttt gaaacgttgt ttagaaaagc
      601 caaagaaaag agaaacgcct actatcaaga tgatttgaca actgcctttc gtctctttaa
      661 tcaagaggga gatggctttg ggggtctgac agtggacctt tatggcgact acgccgtctt
      721 ttcttggtat aactcttatg tttatcagat tcgtcagact atatcagaag cctttagaca
      781 ggttttccct gaggttttag gggcttatga gaaaatccgc tttaagggtt ttgactatga
      841 atctgcccat gtttatggtc aagaagcacc tgactttttc actgttttag aaaatggtgt
      901 cctgtatcaa gtctttatga atgatggctt gatgacagga attttcctag accagcatga
      961 ggttcgcggt agtttagttg acggcttggc tatgggtaaa tccttgctca atatgttttc
     1021 ctacacagcg gctttttcag tagctgcggc catgggagga gctagccaga caacttctgt
     1081 tgatctagcc aaacgttcac gagaattgtc tcaagcgcat tttcaggcaa atgggctcag
     1141 cacagacgag catcgtttta tagtcatgga tgtctttgag tatttcaaat atgccaaacg
     1201 caaagacttg acctacgatg tgattgtcct agatccgcct agctttgctc ggaataaaaa
     1261 acaaactttc tctgtggcca aggattatca caagttgatt tcccagagtc ttgagatttt
     1321 aaatccggga gggattatca ttgccagtac caatgctgcc aatgtttccc gtcagaaatt
     1381 tacagaacaa attgataaag gctttgcagg aagaagttac cagattttaa acaaatatgg
     1441 tcttccagca gattttgcct ataataaaaa agatgaaagt agtaattacc tcaaggtgat
     1501 tagtatgaag gttagtaaat gaaattaatc gtttcagtaa tgccaagaag tttagaggag
     1561 gctcaggctc tggatgccac gaggtacctg gatgccgaca tcattgaatg gcgtgccgac
     1621 tatctgccta aagaagcgat tttgcaggta gctccagcca tttttgaaaa attcgcaggc
     1681 cgtgagttgg ttttcacgct acgaactcgc tccgaaggtg gagaaatcga cctttctcca
     1741 gaagagtata tccatctaat caaggaagtt gcgcaattct atcaaccaga ctatattgat
     1801 tttgagtact atagctacaa ggatgttttt gaggaaatgc tggacttccc aaatcttgtt
     1861 ttgagttacc ataatttcca agaaacacct gagaacatga tggaaatctt gtcagagttg
     1921 acgatcctaa atccaaaact tgttaaggtt gcggtgatgg ctcacacgga gcaggatgtc
     1981 ttagacttga tgaactatac acgaggcttt aaaaccctca atcctgaaca ggaatatgtg
     2041 accatttcta tgggtaaggt gggcaaggtc tctcgtatca ctgcggatgt gactggttcg
     2101 agttggtctt ttgccagtct ggatgaggtt agtgcccctg ggcagatttc tctagctagc
     2161 atgaaaaaaa tcagggagat tttggatgaa gcttgatggc tatacacgtt tagctgcagt
     2221 tgttgccaat cctattaagc attctatttc tcccttcatc cacaatagag cctttgaggc
     2281 gacagctacc aacggtgctt atgtggcttg ggagattgaa gcgagtgact tggcagaaac
     2341 agtggccaat attcgtcgct accagatgtt tggcatcaat ctgtccatgc cctataagga
     2401 gcaggtgatt ccttatttgg ataagctgag cgatgaagcg cgcttgattg gtgcggttaa
     2461 tacggttgtc aatgagaatg gcaatttaat tggatataat acagatggca agggattttt
     2521 taagtgcttg ccttctttta caatttcagg taaaaagatg accctgctgg gtgcaggtgg
     2581 tgcggctaaa tcaatcttgg cacaggctat tttggatggc gtcagtcaga tttcggtctt
     2641 tgttcgttcc gtttctatgg aaaaaacaag accttaccta gacaagttac aggagcagac
     2701 aggttttaaa gtggatttgt gtgctttaga gaatgtttct gaactgcaag caaggattgc
     2761 cgagtcggat ttgctagtta atgccaccag tgtgggcatg gatggccaat cctctcctgt
     2821 tcctgaaaac atagtcttac cagaaactct cttagttgca gatatcatat accaaccctt
     2881 tgaaacaccg tttttgaaat gggctagaag tcagggcaat ccagcagtca atggtctggg
     2941 aatgttgctc tatcaagctg cagaagcttt tcaactgtgg acaggcaagg aaatgccgac
     3001 agaagagatt tggcagtctt taacagaaaa ataccaataa agaaagggag actctcctat
     3061 gaaaatcaga atcgatattc ctcatcatcc ttatgatatt cagattgaaa aaggttgtat
     3121 ggcccaggct ggtcagtggt tgcgagaact ctggcaaccg caaaaggtag tcattgtgac
     3181 agataaccat gtagcctctc tctatgcaga gaaggtcaag ctcagcctag aagatgctgg
     3241 ttttcaggta gctgtttttg atttcttaga aggtgaagaa agaaagaatt taactactgt
     3301 tcagaaagtc tatgaatttc tagtcaagca aggtctgact cgtagcgatg gaatcgttgc
     3361 tcttggtggt ggcgttgttg gggacctggc tggatttgta gcctctacct atatgcgggg
     3421 tattcacttt gttcagattc cgactagttt gacagctcag gttgattctt ctatcggtgg
     3481 aaagacaggc gttaacacac catttgctaa aaatatggtg gggacctttg cccaaccaga
     3541 tggggttctg attgatccac ttgttcttga aaccctcgga aaaagagagt tgattgaagg
     3601 gatgggtgaa gttatcaagt atggcttgat tgaggatcca gaactgtggg ctctcttgac
     3661 ggaactgaat ggttctgttg agagcatttt ggaacatgca gagaccttga ttgaacattc
     3721 ttgtcaggtg aagcgcaaga tggtggttga agatgagttg gacaatggta ttcgtcttta
     3781 cctcaatttt ggccacacta ttggccatgc catcgaagcg actgccggtt atggcaaggt
     3841 catgcatgga gaggctgttg ccatgggaat ggtacagatt tccaaggttg ctgaggaaaa
     3901 aggcctcatg ccagctggca ttacccaatc tatcacagag atgtgtcaga aattcggctt
     3961 gcctgttgac tatgaaaatt gggaagttga caagctttat caggctctta ctcatgacaa
     4021 gaaaacgcgt ggtaacacct tgaaattggt cttggtgtca gagcttggtt cagcgatcat
     4081 tcacccagtt tctctggaag agatgaaaga ctacttggta aaataaggag agtgtatgag
     4141 atatttaact gcaggagaat cacacggccc ccgtctaaca gctattattg agggaattcc
     4201 agctggactt ccattgacag ctgaggatat caatgaggac cttagacgcc gtcagggtgg
     4261 ctacggtcgt ggtggtcgta tgaagattga gagtgaccag gttgtcttta cttcgggcgt
     4321 tcgccacggg aagacgacag gggcgcctat tactatggat gtcatcaata aggaccacca
     4381 gaaatggctg gacatcatgt ctgcggagga cattgaagac cgccttaaaa gcaagcggaa
     4441 aattactcat cctcgcccag gtcatgccga tttggttggg gggattaagt accgttttga
     4501 tgatttgcga aattctttgg agcgttcatc agctcgtgaa accaccatgc gggtggcagt
     4561 tggtgcagta gccaaacgcc tcttggctga gctggatatg gagattgcca accatgtcgt
     4621 ggtctttggt ggcaaggaaa tcgatgttcc tgaaaatctg acagtcgctg aaattaagca
     4681 aagagctgcc cagtctgaag tttctattgt taaccaagaa cgagaacagg aaatcaagga
     4741 ctatattgac caaatcaaac gtgatggtga taccatcggt ggggttgtgg agacagtcgt
     4801 cggaggcgtt ccagttggtc ttggttccta tgtccaatgg gatagaaaat tggatgcaag
     4861 attggctcaa gctgttgtct ctatcaatgc ctttaaaggg gtggaatttg gtcttggctt
     4921 tgaggctggt tatcgtaaag gcagccaagt tatggatgaa attctctggt ctaaagaaga
     4981 cggttatact cgccgtacca ataatctagg tggttttgaa ggtggtatga ctaatgggca
     5041 acccatcgtt gttcgtgggg tcatgaaacc cattcctact ctttataaac ctcttatgag
     5101 tgtggatatc gaaacccacg aaccttacaa ggcaaccgtg gagagaagtg atccgactgc
     5161 tcttccagct gcaggaatgg tcatggaagc agttgtagca acggttctgg cgcaagaaat
     5221 cctcgaaaaa ttctcatcag ataatcttga ggaactaaaa gaagcggtag ccaaacaccg
     5281 agactataca aagaactatt aaggagttcc tatggcaaaa acaatctata tcgcaggtct
     5341 tgggttgatt ggagcctcta tggcacttgg tatcaaacgc gatcatccag attatgaaat
     5401 tttaggttat aatcgtagtc aagcttcgag agatatcgcc ttgaaagaag gcatgattga
     5461 ccgtgcaacg gatgattttg ctagttttgc tcctttggca gatgtcatta tcctcagctt
     5521 gccaatcaaa caaactattg ctttcattaa ggagttggcc aatttggatt tgcgagaagg
     5581 cgttattatt tcagatgctg gttcgaccaa gtcaaccatt gtggatgcgg cggagcagta
     5641 tttggctggc aagtctgttc gctttgtcgg ggcccatccc atggctggta gtcacaagac
     5701 aggggctgct tcggcagatg tcaatctttt tgaaaatgcc tattatatct ttacaccttc
     5761 aagcctgaca agtcaggaca cgcttaagga aatgaaggat ctgctttcag gtcttcatgc
     5821 tcgttttatc gagattgatg ccaaggagca tgatcgtgtc acttctcaga ttagccattt
     5881 tcctcatatt ttggcttcta gtctcatgga gcagactgcg gtctatgctc aagagcatga
     5941 gatggcaagg cgctttgcgg caggtggttt tcgagatatg acccgaattg cggaaagcga
     6001 gccaggaatg tggacctcca ttctcttgtc caatagcgag accattctgg atagaattga
     6061 ggatttcaag gaacgtttgg aagtgattgg tcaggccatt agtaagggag atgaagagca
     6121 aatttggaac ttttttaacc aagcgcgtga acaacgccag accatggaaa tccataagcg
     6181 tggtggtgtg gatagctctt acgacctcta tgttgacgtt cctgatgaag aagatgtcat
     6241 cctgcggatt ttggaactgc tacgtgggac ttccttggtt aacatccaca tcaacgagga
     6301 aaatcgtgag gatattcacg gaatcctaca aatttcattt aaaaatgctc aagacttgga
     6361 aagagctgag catctcataa cagaaaatac cgactataca gtcgtcatca aataaggaga
     6421 agaacatgtc aaatatttac gatagtgcaa acgaactcag tcgcggtcta cgcggattac
     6481 cagaatacaa ggctgttaaa gcagctaaag atgcgattgc agcagatgct gaggcaagca
     6541 aaatctttac agaatatctt gcctttcaag aggaaattca aaaactagca catacaggtc
     6601 aaatgccaga tgcgtccttc caagctaaga tggaaggctt tggtaaacag attcaaggaa
     6661 atagcctctt gtcagaattc tttaccaagc aacaacaatt ggccatttac ctttctgaca
     6721 ttgaaaaaat tgtttttgaa ccagtttcag aattgctgaa ataagaaaag aacgatccta
     6781 aagtcaggaa tttttaagga atttctggct ttttatgata aaataggtaa aagtattgca
     6841 agtatgaggt ccagtatgaa actaaaaaca aacattcgcc atttacatgg tagtatccgc
     6901 gtcccaggtg acaagtctat cagccaccgt tccattatct ttggaagttt ggctgagggt
     6961 gagaccaagg tttatgatat tctgcgaggt gaagacgttc tttcgaccat gcaggttttt
     7021 cgtgaccttg gtgttgaaat tgaggataaa gatggggtta ttaccattca aggtgtaggc
     7081 atggctggct taaaagcgcc acaaaatgcc cttaatatgg gaaattctgg cacctcgatt
     7141 cgcctgattt caggtgtcct tgctggtgca gatttcgaag tagagatgtt tggagatgat
     7201 agtctttcca aacgtcctat ggaccgtgtg acccttccac tgaaaaaaat gggcgtcagc
     7261 atttcagggc aaactgaacg agacttgcct ccccttcgct taaaagggac gaaaaaccta
     7321 agacctattc attatgagtt gccaattgcc tctgcccaag tcaagtcagc cttgatgttt
     7381 gcagccttac aagctaaggg ggagtcagtt attatcgaaa aagagtgcac ccgtaatcat
     7441 actgaagata tgttgaaaca atttggtggt catttaagtg tggacggtaa gaaaatcaca
     7501 gtccaagggc cacaaaaatt gacaggacag aaggtggtcg taccaggaga tatttccagt
     7561 gcagcctttt ggttagtcgc aggtttgatt gttccaaatt ctcgtctagt gctgcagaat
     7621 gtggggatca acgaaactcg caccggtatt attgatgtca ttcgtgccat gggtggaaaa
     7681 ttggaaataa ctgaaatcga tccagtcgct aaatcttcta ccttgactgt tgagtcttct
     7741 gacttgaaag gaacagagat tggtggcgct ttgattccac gattgattga tgaattgccc
     7801 attattgccc tgcttgcgac tcaagcccaa ggtgtaacag ttatcaagga tgctgaggag
     7861 ctcaaggtca aggaaacaga ccgtattcag gttgtggcag acgccttaaa tagtatggga
     7921 gcagatatta ctcctacggc agatgggatg attatcaaag ggaaatcagc tcttcacggt
     7981 gctagagtca atacgtttgg tgaccaccgt atcggcatga tgacagctat cgcagccctc
     8041 ttggttgcag atggagaggt ggagcttgac cgtgcagaag ccatcaatac cagctatcct
     8101 agtttctttg atgatttgga gagcttgatt catggctaag gtgttattag ggtttatggg
     8161 ggctggaaaa tcgactattg caagaggctt ggaccctaat taccttgata tggatgctct
     8221 gattgagaag cgcctaggta tgtccattgc gaattttttc gctgaaaagg gagaagcagc
     8281 ctttcgtcag gtagaatcag aagtcctagc tgatttacta caaacagacc aagtcgtgtc
     8341 aactggagga ggagtggtta tttctcagag aaatcgtgac ttactcaaga ctaatacaga
     8401 taacatctac ctgaaagcag attttgaaac cctctaccaa cgtatcgcag ctgataagga
     8461 caatcagcga ccgctttttc taaataatag caaggaagaa ctagtagcta tttttcaaga
     8521 aagacaggct tggtatgagg aagtggctag tcgggttttg gatgtgacca agctaagccc
     8581 agaggaaatt atagaggaac taagatgaaa attgcttatc taggtcccaa gggatcattt
     8641 tcacaccacg ttgtgcagat agcttttcct catgaggaat tgcaggcttt tgctaacatt
     8701 acagatgtca tcaaggctta tgagcaagga ttagtggact attctgtggt gccagttgaa
     8761 aattctattg agggtagtgt tcatgaaacc ttggactatc tttttcatca ggctcacatc
     8821 caagcagtag cagaaatcgt tcagcctatt catcagcagt tgatggtggt tccaggccat
     8881 actaagattg aaaagatttt ttcacatcca caggccttgg ctcaaggaaa gaaattcatc
     8941 gatgaacaat atccagaggc tcaaatcgag gtaacagcta gtacagctta tgcggcccgt
     9001 tttatttccg aacatccaga ccagcccttt gcagcagttg cacctagaag ttctgctgaa
     9061 gaatatggat tggaactgat tgccgaggat attcaggaaa tggaagccaa tttcacacgt
     9121 ttctgggttc taggagctga aaagcctagt attcccttgc aagcacaaac tgaaaagatg
     9181 agtttggcct tgacattacc tgacaacctt ccaggtgcac tttataaggc cctgtcgacc
     9241 tttgcttggc gaggaattga cttgacaaaa attgaaagtc gtccactcaa gacagcactg
     9301 ggtgaatact ttttcattat cgatgtggat tataccgata aggacttggt ccactttgcc
     9361 caaaaagaat tagaagcgat tggaatccag tataaaattc tgggtgccta tcctatttat
     9421 ccaatatcag accatggaaa ggagagaaga tgagtaaaga aaatccctta agtcatcatg
     9481 agcagttgcg ttatgattat ttgctaaaaa atattcacta tctcaatgag agagaaaaaa
     9541 atgagtttgc ctatttgcaa gaaaagctaa ctcttgctag gggaaatagt agctctagct
     9601 tggaacaaga aagagaagag caggttgact taccaagcta tgcgaaccgg agtcgctcac
     9661 aatccaaatc acaagcactc tctttccctc caaaaaagaa aagacggaag ctccgtctta
     9721 aacgaatttt tatggtgatt ttttcacttt tggtctgtgt ggctttggcc atggtattca
     9781 tgtttttgcg tggttaccaa gatgctagcg caaagaaaac tgctgatgcc cgggcagctc
     9841 aagtagaagt ctttaatggt caggacacta gagatggagt taatatttta atcatgggta
     9901 ctgatggtcg aatcggccag aacagtgttg agacacgaac tgactctatt atggtattaa
     9961 atgtcggggg ctcagataag aaaatgaagc tagtcagttt catgcgtgat aatttggtct
    10021 atatagatgg ttatagtcaa gtgattaacg gtagaaaaca gacagataac aagttaaacg
    10081 tagcctacga gttaggagaa caagaggggc aaaaaggggc agaaatggtt cgccaagtct
    10141 tgaaagataa ttttgacttg gacattaagt actacgcctt ggttgatttc caggcctttg
    10201 ccacagcgat tgacacgctt ttccctgatg gggtgacgat tgatgctcaa ttttcaacat
    10261 tgaatgggcg tcccctaaca gaagctacag tcggagatga tttatacgct accgagactg
    10321 agtctccaac ccaaaccatt aaagtcggaa aacagcagat gaatggctcg accctgctca
    10381 attatgctcg tttccgtgat gatgatgagg cggattacgg ccgtacaaaa agacagcaac
    10441 aagttttaac agcaatttta gagcaaatta aagatcccac taaacttttc actggttctg
    10501 aagctcttgg aaaggttttt gctatgacct caaccaacgt accctatact ttcctcctaa
    10561 caaacggttt atctgttttg gatggagcaa aaaatggtat tgaaaaattg acgattccag
    10621 aactgggtga ctgggtagat gcctatgatg tttatggagg cttgggcttg ctggttgatc
    10681 aaaacaaata tcaaaccaag ctcgctcaaa tgggcttgag ataagataat actcaatgaa
    10741 aatcaaagtg caaactagga agctagccgc aggctgctaa aaacacagtt ttgaggttgt
    10801 agataagact gacgaagtca gttacctata cctacggcaa ggtgaagctg acgtggtttg
    10861 aagagatttt cgaagagtat aagacagaaa aatcaaagtt tgatagctat ttggatagca
    10921 gtcaggcttt gattttttac agtctgcaat agattttcac cccttgtttg tggtataatg
    10981 aaacgatacg atagaaagaa taatgaacaa tatgactgat ttaaaagcaa ttcaggctcg
    11041 tagtctggag atggctgaat attttgtggc cttttgtaaa gaacatgatt tgctctgtta
    11101 tctctgtggc ggaggcgcta ttggtgccct tcgaaacaag ggatttattc cttgggacga
    11161 cgacctagac ttttttatgc ctcgtaaaga ttatgagaaa ttagcagaat tatggcctcg
    11221 ttatgcagat gaacgttatt tcttgtcaaa gagtcacaag gattttgttg atcgtaatct
    11281 ttttattacc attcgtgaca aggaaaccac ctgtatcaag ccttatcagc aggatttgga
    11341 tttgccacat ggtctggcct tggatgtttt gcctttggat tattatccga aaaatccagc
    11401 tgagcggaaa aaacaggttc gttgggcctt gatttattca ctcttttgtg cgcaaactat
    11461 tccagaaaag catggtgctc tcatgaaatg gggaagtcgc attttactgg gtttgactcc
    11521 aaaatctctc tgttatcgca tctggaaaaa agctgagaaa gaaatgacta agtatgattt
    11581 ggctgattgt gatggcatta cagaattatg ctcaggtcct ggctacatga gaaacaagta
    11641 cccaatcaca tcttttgaag acaatctttt cttgccattt gaaggaacag agatgcctat
    11701 tccaatcggc tatgatgtct atctcagaac tgcttttggg gattatatga cgcctccacc
    11761 agcagacaag caggtaccgc atcatgatgc tgtcatcgct gatatggata agtcttatac
    11821 agaatacaag ggagaatatg gtggctaaga aaaaaatctt attttttatg tggtcttttt
    11881 ctcttggagg tggtgcagag aagattctat caaccattgt ttcaaatctg gatccagaaa
    11941 agtatgatat tgatattctt gaaatggagc actttgacaa gggatatgaa tctgttccaa
    12001 agcatgtacg cattttaaaa tcccttcaag attatcgcca aaccagatgg ttacgagctt
    12061 ttttgtggag aatgagaatt tattttccaa gactggctcg tcgtttgctt gtaaaagatg
    12121 attatgatgt tgaagtttct tttaccatta tgaatccacc actgttgttc tctaaaagaa
    12181 gagaagtcaa gaagatatct tggattcatg gaagtattga agaacttctt aaggatagct
    12241 ctaaaagaga atcacataga agccagttgg atgctgcgaa tacaattgta gggatttcaa
    12301 aaaagaccag caattctatc aaggaagttt atccagatta tacttctaaa ttacagacaa
    12361 tctacaatgg atatgatttt cagactattc tagaaaaatc tcaagagaag atcgatatcg
    12421 agattgctcc tcaaagtatc tgtactatcg gacggattga ggaaaataag ggttctgacc
    12481 gtgtagtgga agtgatacga ttattacacc aagagggaaa aaactatcat ctctatttta
    12541 tcggggctgg tgatatggaa gaggaactga aaaaacgagt caaagagtat gggattgagg
    12601 actatgtaca tttccttggt tatcaaaaaa atccttatca gtatctatct cagacgaaag
    12661 ttcttttgtc tatgtctaaa caagaaggtt ttcctggagt gtatgtggag gccttgagtc
    12721 tgggactccc ttttatctct acgaacgttg gaggggctga ggaattatcc caagaaggac
    12781 gatttggaca aatcattgag agcaatcaag aggcagctca ggcgattact aattacatga
    12841 cttctgcctc aaactttgat gtcgatgagg ctagccaatt cattcaacaa tttacaatta
    12901 caaaacaaat cgaacaagta gaaaaactat tagaggagta gcatggaaac tgcattaatt
    12961 agtgtgattg tgccagtcta taatgtggcg cagtacctag aaaaatcgat agcttccatt
    13021 cagaagcaga cctatcaaaa tctggaaatt attcttgttg atgatggtgc aacagatgaa
    13081 agtggtcgct tgtgtgattc aatcgctgaa caagatgaca gggtgtcagt gcttcataaa
    13141 aagaacgaag gattgtcgca agcacgaaat gatgggatga agcaggctca cggggattat
    13201 ctgattttta ttgactcaga tgattatatc catccagaaa tgattcagag cttatatgag
    13261 caattagttc aagaagatgc ggatgtttca agctgtggtg tcatgaatgt ctatgctaat
    13321 gatgaaagcc cacagtcagc caatcaggat gactattttg tctgtgattc tcaaacattt
    13381 ctaaaggaat acctcatagg tgaaaaaata cctgggacga tttgcaataa gctaatcaag
    13441 agacagattg caactgccct atcctttcct aaggggttga tttacgaaga tgcctattac
    13501 cattttgatt taatcaagtt ggccaagaag tatgtggtta atactaaacc ctattattac
    13561 tatttccata gaggggatag tattacgacc aaaccctatg cagagaagga tttagcctat
    13621 attgatatct accaaaagtt ttataatgaa gttgtgaaaa actatcctga cttgaaagag
    13681 gtcgcttttt tcagattggc ctatgcccac ttctttattc tggataagat gttgctagat
    13741 gatcagtata aacagtttga agcctattct cagattcatc gttttttaaa aggccatgcc
    13801 tttgctattt ctaggaatcc aattttccgt aaggggagaa gaattagtgc tttggcccta
    13861 ttcataaata tttccttata tcgattctta ttactgaaaa atattgaaaa atctaaaaaa
    13921 ttacattaga acgggggtga ccaagtgatt gatgggaaac gattattatt tagtttgacc
    13981 atagtcagtt atgccttgac gctagtaagt ggaattgtgt atctgtttaa taataataat
    14041 gttagcttac tttctacttt attgttcttg ttggttagta gcttaattgc ttgttggaat
    14101 gatatcaagt attacttaat ccattttatt ttctatttaa ccatttttgt atttctggta
    14161 tcaagaccga ccattgatta ttttagggat ggtgctttgg atacctatca tccaatagcc
    14221 tatcgttttg cctttatagt tgtcatggtt tcgattctgg gcttgaccac aggaggcatt
    14281 ctggctcgtt acttcatagc taggaagaaa ataaaagtag caaatatagg aaattctcta
    14341 aaagaggttt atatcaagcg gttacgcttt gtatcactag gagtttttct tctaacctat
    14401 cctttctatt tcattcggtt atttgaacgg ctcttgtatc gtttgcagac ttcctactat
    14461 gcctactatg caaattttga aagtaaactg ccttatttta cctacatttt gtctaccttt
    14521 acggtctatg caatgtgtat gtatctggca accaagccaa agaaattgca ggccacagca
    14581 gtgcttgtct cctttattgc agctaatact attcatttgg caattgggac acgaaatccc
    14641 tttattttaa gtattttatt tgcttttgtt tattacttta tgcgggagca aactgaaaaa
    14701 ggaaaatgga ttgggtttaa agaaaagtta gcgatttttg taggttctcc tattctcatg
    14761 ttagcgatgg gagtactcaa ttatgtacgg gataatgtcc aagtttctca tacaggtttc
    14821 tgggatatct tacttgactt tatctataaa caagggacta gttttggtgt tctggctcga
    14881 ggttttctat ttaacagtag cctcccttac cgagatttcc gtaattttac ttttggtcct
    14941 gttcttgatt attttgcaag ggggagtttg ggagccattt tcggaggaaa agcctttgaa
    15001 catacaacca atagtgtgga actagctatt gatagtaata gttatgccca caatctatcc
    15061 tatcttgtct tgaacaagga atacttgaaa gggcatggta tcggaagtag ttatatcatg
    15121 gagttgtata ccgactatgg tatgattgga gtctttctgc ttagtttctt actcggcgta
    15181 ttatttatag ccatgctgca agtagcctat cgctcaagga caatcctatt tgctttatcc
    15241 ctactcatct tgaataatct attctttatg ccaagaagca gcttttcaga aagtttcttc
    15301 aatttattta caatgcaatt ctggggaatt gttcttgtga ttatatttgt agcaaaaatg
    15361 cttacaaagg aaaactagta tctactaaac aaaggagaaa aaaatcatgt ttgaacatta
    15421 ttcagtagct gatttgtttg caaatcttta taaaaagcga aaagcaaata ttttagctct
    15481 catcgcttta tttgctctca ttgctgtacc atttacaatt aaagcagtta ggaataaaaa
    15541 cactgtcaaa gatacaacaa gttattcaac ttatcttatc tataaaatca ctcctccaaa
    15601 agagtcggcc aaaacgattt tgaatcatca aattggtggt tatagtgatt tttatgggaa
    15661 attgattgat ggtaatttga atggagctta tcttttcaat gatgtagaac ccagtgagtt
    15721 gaaaaaaatt gccagtgaat tagacacgac agaaacaacc ttgaaaaatt caacgaatga
    15781 ctattggtgg aaaaaattga ccgtctacta tatgattgac gatgcagggg ttggtgtgaa
    15841 aattttgaca tcaagtaaag atgccaatga cttgttagag aaaaaaattg atgggttgat
    15901 tgagaaattt aaacatgcct atgcaaatgt gaaaattgaa aaactggaaa ccatcaactc
    15961 taaagaattg aacgcaaatg gtgaaacagc gcttggctta aatgtgaaaa atctgattct
    16021 tcgtttagtt gttattggag tggtttgtgt gattttggtt gtgatgggaa atgtgttagt
    16081 ttatctcttt aatccaacaa tcaatagagt aggtgatttt tctcagtatc aaattgattt
    16141 tgtaacagag attacaacaa ttgctaacct agcagatgtt ttgtcataca aaaatactgg
    16201 acaggaattg accatcgtta gctcaaataa agctatccta gataaattga aacagagtca
    16261 agaagcttta aaaggaatgc attttgtaga tttacaggat gtatcatctc ttttggaaag
    16321 agatacagtc cttcttgttg aagagtacgg agtgactcgt tataagaaat ttgagcaaag
    16381 tcttcaaatt ctcagaaact taaatcgttc tatccttggt gtagcaacct ttaaattata
    16441 agtattctga tgtataaggt cttcaaaatc ggctaagagc tgattttgaa ggctttttct
    16501 atctgtctgc agaaattttc ttttggagtc tcctatagaa agaccctagg gaaaatctat
    16561 ccgtatagag gagccttctt ttgataaaat cgtaaaaatc tagtataata gatagaactg
    16621 aaagtatgag gttactagca atgaaaatga aacaaattag tgatacaact ttaaaaatca
    16681 cgatgtcttt agaggatttg atggatcgtg gaatggagat tgctgacttt ctcgttcctc
    16741 aagaaaaaac agaagagttc ttttatgcta tcttggatga actagagatg cctgatagct
    16801 ttctggatac aggcatgttg agcttccgtg tgactccaaa acctgataag gtagatgtct
    16861 ttgtgaccaa gtcaaagatt gaccaaaatc tagattttga agacttatcg gatttgccag
    16921 atatggaaga attggctcaa atgtctccag atgaatttat caaaaccctg gaaaaaagca
    16981 tcgcagacaa aaccaaggat gatatcgaag ccattcaatc tcttgagcaa gttgaagcca
    17041 aggaagaaga gcaagagcag gctgaacaag aagctgagag taagaaagaa ccttacatct
    17101 actacatcct ttcttttgct aagttggctg acttggtagt ttttgccaag acagtgactt
    17161 ttgaaatgga aacttctgaa ctctacaaaa tgaacgagcg ctattatttg accattttag
    17221 tggatattga aaatcatcca agcccatatc cagcttggct gttggcccgt atgcgcgagt
    17281 ttgcagacga tagtgatatc agtcgctcag tcttacaaga gtatggtcaa gtcttgatga
    17341 gtcacgatgc agtgctcaat ctgcaaaaaa tcggctaatc ctttctggaa agctattttc
    17401 agattttaag aagagcgaat cgtctgattc gttttttctt tttatactga aatagtgatt
    17461 tactataata ggaattttca caaaattctg ttataatggc tatattagaa aatttcgagg
    17521 agataaagat gacagttaaa attgctttac taggatttgg taccgttgca agtggtgtgc
    17581 ctttcctcct aaaggaaaat ggaggaaaaa tcaatcaatc agcacattca gatatcaaag
    17641 ttgctaaggt attggtcaag gatgaagatg aaaaaaatcg cttgcttgca gcagggaatg
    17701 actttaactt tgtaaccaat gtggatgata ttttatcaga ccaggatatt actatcgtag
    17761 tggaattgat ggggcgtatt gagcctgcta aaacctttat cactcgtgcc ttggaagctg
    17821 gaaaacacgt tgttactgct aacaaggacc ttttagctgt ccatggcgca gaattgctag
    17881 aaatcgctca agctaacaag gtagcacttt actacgaagc agcagttgct ggtgggattc
    17941 caattcttcg tactttagca aattccttgg cttctgataa aattacgcgc gtgcttggag
    18001 tagtcaacgg aacttccaac ttcatggtga ccaagatggt ggaagaaggc tggtcttacg
    18061 atgatgctct tgcggaagca caacgtctag gatttgcaga aagcgatccg acgaatgacg
    18121 tagatgggat tgatgcagcc tacaagatgg ttattttgag ccaatttgcc tttggcatga
    18181 agattgcctt tgatgatgta gcccacaagg gaatccgcaa tatcacacca gaagacgtag
    18241 ctgtagctca agagtttggt tacgtagtga aattggttgg ttctattgag gaaacttctt
    18301 caggtattgc tgcagaagtg actccaacct tcctacctaa agcgcaccca cttgctagtg
    18361 tgaatggcgt aatgaacgct gtctttgtag aatctatcgg tattggtgag tctatgtact
    18421 acggaccagg tgcgggtcaa aaaccaactg caacaagtgt tgtagctgat attgtccgta
    18481 tcgttcgtcg tttgaatgat ggtaccattg gcaaagactt caacgaatat agccgtgact
    18541 tggtcttggc aaatcctgaa gatgtcaaag caaactacta tttctcaatc ttggctccag
    18601 actcaaaagg tcaggtcttg aagttggctg aaatcttcaa tgctcaagat atttccttta
    18661 agcaaatcct tcaagatggc aaagagggtg acaaggcgcg tgtcgttatc atcacacaca
    18721 agattaataa agcccagctt gaaaatgtct cagctgaatt gaagaaggtt tcagaattcg
    18781 acctcttgaa taccttcaag gtgctaggag aataagatga agattattgt acctgcaacc
    18841 agtgccaata tcgggccagg ttttgactcg gtcggtgtag ctgtaaccaa gtatcttcaa
    18901 attgaggtct gcgaagaacg agatgagtgg ctgattgaac accagattgg caaatggatt
    18961 ccacatgatg agcgtaatct cttgctcaaa atcgctttgc aaattgtacc agacttgcaa
    19021 ccaagacgct tgaaaatgac cagtgatgtc cctttggcgc gcggtttggg ttcttccagc
    19081 tcggttatcg ttgctgggat tgaactagcc aaccaactgg gtcaactcaa cttatcagac
    19141 catgaaaaat tgcagttagc gaccaagatt gaagggcatc ctgacaatgt ggctccagcc
    19201 atttatggta atctcgttat tgcaagttct gttgaagggc aagtctctgc tatcgtagca
    19261 gactttccag agtgtgattt tctagcttac attccaaact atgaattacg tactcgcgac
    19321 agccgtagtg tcttgcctaa aaaattgtct tataaggaag ctgttgctgc aagttctatc
    19381 gccaatgtag cggttgctgc cttgttggca ggagacatgg tgaccgctgg gcaagcaatc
    19441 gagggagacc tcttccatga gcgttatcgt caggacttgg taagagaatt tgcgatgatt
    19501 aagcaagtga ccaaagaaaa tggggcctat gcaacctacc tttctggtgc tgggccgaca
    19561 gttatggttc tggcttctca tgacaagatg ccaacaatta aggcagaatt ggaaaagcaa
    19621 cctttcaaag gaaaactgca tgacttgaga gttgataccc aaggtgtccg tgtagaagca
    19681 aaataaagaa tagaagatag gatggggaaa ctcttaacca gagggtttca tatccttttt
    19741 gtgaaaagaa gtttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc
    19801 tgctcaaaac a
//
LOCUS       DAVLAQ010000032        19040 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000032 DAVLAQ010000000
VERSION     DAVLAQ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.032"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..97
                     /locus_tag="VXB71_001287"
     CDS             <1..97
                     /locus_tag="VXB71_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0451399.1"
                     /translation="YDLEPMAQQVIPKAAFGYIASGAGDTFTSFQ"
     gene            225..1715
                     /gene="lysS"
                     /locus_tag="VXB71_001288"
     CDS             225..1715
                     /gene="lysS"
                     /locus_tag="VXB71_001288"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0451400.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            2340..3476
                     /gene="lctO"
                     /locus_tag="VXB71_001289"
     CDS             2340..3476
                     /gene="lctO"
                     /locus_tag="VXB71_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0451401.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLRLY"
     regulatory      3730..3818
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4033..4701
                     /locus_tag="VXB71_001290"
     CDS             4033..4701
                     /locus_tag="VXB71_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0451402.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLIMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            4938..5720
                     /gene="thiM"
                     /locus_tag="VXB71_001291"
     CDS             4938..5720
                     /gene="thiM"
                     /locus_tag="VXB71_001291"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0451403.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPE
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            5722..6351
                     /locus_tag="VXB71_001292"
     CDS             5722..6351
                     /locus_tag="VXB71_001292"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0451404.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      6560..6648
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6910..7470
                     /locus_tag="VXB71_001293"
     CDS             6910..7470
                     /locus_tag="VXB71_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0451405.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            7471..8856
                     /locus_tag="VXB71_001294"
     CDS             7471..8856
                     /locus_tag="VXB71_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451406.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            8858..9508
                     /locus_tag="VXB71_001295"
     CDS             8858..9508
                     /locus_tag="VXB71_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0451407.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            9519..10211
                     /gene="tenA"
                     /locus_tag="VXB71_001296"
     CDS             9519..10211
                     /gene="tenA"
                     /locus_tag="VXB71_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0451408.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            10216..10740
                     /gene="thiW"
                     /locus_tag="VXB71_001297"
     CDS             10216..10740
                     /gene="thiW"
                     /locus_tag="VXB71_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0451409.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            10740..11543
                     /locus_tag="VXB71_001298"
     CDS             10740..11543
                     /locus_tag="VXB71_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0451410.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            11536..12168
                     /locus_tag="VXB71_001299"
     CDS             11536..12168
                     /locus_tag="VXB71_001299"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0451411.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(12377..13168)
                     /gene="thiD"
                     /locus_tag="VXB71_001300"
     CDS             complement(12377..13168)
                     /gene="thiD"
                     /locus_tag="VXB71_001300"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0451412.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(13252..13350)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13534..13929
                     /locus_tag="VXB71_001301"
     CDS             13534..13929
                     /locus_tag="VXB71_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0451413.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            13940..14311
                     /locus_tag="VXB71_001302"
     CDS             13940..14311
                     /locus_tag="VXB71_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0451414.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            14321..16564
                     /locus_tag="VXB71_001303"
     CDS             14321..16564
                     /locus_tag="VXB71_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0451415.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            16771..18546
                     /gene="spxB"
                     /locus_tag="VXB71_001304"
     CDS             16771..18546
                     /gene="spxB"
                     /locus_tag="VXB71_001304"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0451416.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            18657..19004
                     /locus_tag="VXB71_001305"
     CDS             18657..19004
                     /locus_tag="VXB71_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0451417.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT         5638 a         3519 c         4193 g         5690 t
ORIGIN      
        1 ctatgatttg gagccaatgg cgcaacaagt tattcctaaa gcagcatttg gctatatcgc
       61 tagtggggcg ggagatactt tcacttcttt ccagtgattt tagcgtcagg ttctttttag
      121 tttttaaaga ttatccgtga atttcttgct tatttatgat aaaatgggag tatcgcaaaa
      181 aatgactcat cgtattcaat tttgagtaaa actaggagga tcccatgtct acagaacata
      241 tggaagaact aaatgaccag cagatcgttc gccgtgaaaa aatggctgcg ctccgcgaac
      301 aaggaatcga tcctttcgga aaacgttttg aacgtactgc aaattcacaa gaattaaaag
      361 ataaatatac caacctcgat aaagaacaat tacacgataa aaacgaaaca gctactatcg
      421 caggacgctt ggtaaccaaa cgtggtaaag gaaaagttgg ttttgcccac cttcaagacc
      481 gcgaaggcca gattcagatc tacgttcgta aggatgctgt cggtgaagaa aactacgaaa
      541 tcttcaaaaa agcagacctt ggtgacttcc ttggtgtcga aggtgaagtg atgcgtacgg
      601 atatgggaga actctctatc aaggcaaccc acatcacaca cttgtctaag gctcttcgtc
      661 ctcttcctga gaaattccat ggtttgacag acgttgaaac aatttaccgt aaacgttacc
      721 ttgacttgat ttctaatcgt gaaagctttg aacgctttgt cactcgttca aaaatcatct
      781 ctgaaatccg tcgttacctt gaccaaaaag gattccttga agtggaaaca cctgttcttc
      841 ataatgaagc cggtggtgct gctgcccgtc catttatcac ccaccacaat gcccaaaaca
      901 ttgacatggt gcttcgtatc gcgactgagc ttcacttaaa acgccttatc gtgggtggta
      961 tggaacgtgt ctatgaaatt ggccgtatct tccgtaacga aggaatggac gctactcata
     1021 accctgagtt cacttctatc gaagtttacc aagcttatgc agacttccaa gacatcatgg
     1081 acttgactga aggcattatc caacacgctg ctaaatcagt caaaggtgat ggcccagtca
     1141 actaccaagg tactgaaatc aagattaacg aaccatttaa gcgtgttcat atggtggatg
     1201 ctatcagaga aattactggt gtcgatttct ggcaagacat gactttggaa gaagctaaag
     1261 ctatcgctgc tgagaagaaa gttccagttg agaaacacta cactgaggtt ggtcacatca
     1321 tcaatgcctt ctttgaagag tttgttgaag aaactttaat ccaaccaacc tttgtctatg
     1381 gacatccagt agctgtatct ccactcgcta agaaaaatcc tgaagaccaa cgctttactg
     1441 accgtttcga gctctttatc atgactaagg agtacggtaa tgcctttact gagttgaacg
     1501 acccaatcga ccaacttagc cgttttgaag cccaagctaa agccaaagaa cttggtgatg
     1561 atgaagcgac aggaatcgac tatgactaca ttgaagctct tgaatacggt atgccaccaa
     1621 caggtggttt gggaatcggt atcgaccgtc tctgcatgct cctcactgat acaacaacta
     1681 tccgtgatgt attgctcttc ccaacaatga aataaattct tatcctctgg ctcttaccag
     1741 gggatttttt gattcaaaaa gagactgaat ttaaggagaa aatgaagtgt agtatattga
     1801 agttgaaata gtacactttg atttctaaga cattgttaga aattggttta aattccctaa
     1861 gcaatttgtg catgttttat ttcattttac gatagtacgc tgaaactgtt caaaaagtac
     1921 tagaaattga cttggattcc ccaattgatt tgttcagatt cactataaat aaaaaattaa
     1981 taagtgggat aggaagttag cgtcaactag gatagtatct tgcttaaaca gtatatatgg
     2041 gactgatata agtccatagg tcctattaga ggatgttctg gtgtcttatt cacttgtttt
     2101 tttatagtat tagtagatag aatccgcaaa taaaaaagta gttcaaatgc ctggcagcaa
     2161 aaaatctcaa cgattcactt aatatagact aaggtttaga gtttaaggaa agtagggcta
     2221 gtatattgta tgaaaaaata agatggtttt taagcaaaac tcttgaaaat gattgaaaaa
     2281 agagttatta tagttgtgta gtaaaaagca aacgcttact taatcaagga gggcatttta
     2341 tgtcatacaa aacaagcaat gcagaaggtc atgtagactt catcaatacc tatgatttgg
     2401 agccaatggc gcaacaagtt attcctaaag cagcatttgg ctatatcgct agtggggcgg
     2461 aagatacttt cactttaaga gagaatatcc gcgcctttaa ccacaaactc atcgttcctc
     2521 atacactttg cgatgttgaa aatccaagta cagagattga atttgcaggt gaaaaactat
     2581 cttcaccaat cattatggcg cctgttgcgg cccataaatt agcgaatgaa cagggggaag
     2641 tggcgactgc gcgtggtgtg catgagtttg gttctcttta tacaaccagt tcttactcta
     2701 ctgttgacct tccagagatt tctgaagccc ttcaagggac accccattgg ttccaatttt
     2761 actttagtaa ggatgacggt atcaaccgcc acatcatgga tcgtgtgaag gctgaaggtt
     2821 ataaagcgat tgtcttgacg gcagatgcta ctgtaggggg gaatcgtgaa gtggataagc
     2881 gtaatggttt tgtcttccca gttggcatgc cgattgttga agaatacctg ccagaaggtg
     2941 ctggtaaatc aatggacttt gtttacaaat cagctaaaca acgcttgtct ccacgtgatg
     3001 tagaatttat cgctgaatac tcaggacttc ctgtgtatgt caagggacca caatgccgtg
     3061 aggacgttga acgttcgctt gctgcaggag cttctggtat ctgggtaacc aaccacggtg
     3121 gtcgtcaaat cgacggtgga ccagctgcct ttgactcgct tcaagaagtg gcagaagcag
     3181 ttgataaacg tgtgccaatt gtctttgact ctggtgttcg tcgtggtcaa catgtcttta
     3241 aagccttggc ttcaggagca gacttggtag ctattggtcg cccggttatc tatggcttgg
     3301 ctctcggcgg tagtgttggt gtgcgtcaag tctttgaaca cttgaatgcg gaattgaaga
     3361 cagttatgca gttgtctgga actcagacta ttgaagatgt taaacacttc aaactccgtc
     3421 acaacccata caacccaact ttcccagttg accctcgtga cttaagattg tattgataaa
     3481 agagattgcc tccactgaat gtggaggttt ttcttcgtgt attggaagaa taaatcgcta
     3541 tcgaaaacca tagtaaaatg gaataaaaac aggacaaatc aatcaggaca gttaaatcga
     3601 tttttaacaa tgttttagaa gtagatgtgt actattctag tttcaatcta ctatatataa
     3661 agatattttt cggtcaaata tcttgctagg gctttcattt tttgctatac tggttcagta
     3721 attaaataat agagacattt ggggtgcttt aagctgagat gatacccatt gaacctgata
     3781 cagttaagac tggcgaaggg aaatgtgaaa cgttttttcg tatgacgaaa tgaacgatct
     3841 aatcttgtaa gtcaactcta attcttgatt gtaattggag ttttttgttt atataaactg
     3901 gataggcttg tttagttagc tctctgcaaa tgctctcgat gtgctttaaa aggatcaagt
     3961 ggaattacga ttttgcttga tatttcttgg tgttttatta attactaaca agtaaagaga
     4021 ggagaagtaa atatggaaac acaagactat gcatttcagc caggtttgac tgttggagaa
     4081 ttattaaaaa gcagtcagaa ggattggcag gctgcaatca atcatcgttt tgttaaggaa
     4141 ctttttgcgg ggacaattga gaataaggtc ttaaaggact atctgattca agattatcac
     4201 ttctttgatg ccttcttatc catgctgggt gcctgcgtag ctcacgcaga taaacttgaa
     4261 tccaagcttc gttttgccaa gcaactaggc tttcttgaag cagatgaaga tggttatttc
     4321 caaaaggctt ttaaagagtt aaaagtagca gagaatgact atctagaagt gactttgcac
     4381 cctgtaacaa aagcctttca ggatctaatg tattcggcag tggcttcatc agactatgcc
     4441 catcttttga ttatgctggt cattgcagaa ggtctctatt tagactgggg ttctaaagat
     4501 ttggctttac ctgaagtcta tattcattcg gaatggatca atctccacag aggtcctttc
     4561 tttgcagagt gggttcaatt tctggttgac gaactcaatc gtgtcggtaa aaatcgagaa
     4621 gatttgacag aacttcagca acgctggaat caagcagtcg ctttagaatt agcttttttt
     4681 gatattggtt acgatgtcta gagaaggctc atgatattta caaatttgat gaggtaagac
     4741 tcttcgaaaa tctcttcaaa ccacgtcagt tctatccaca acctcaaaac agtgttttga
     4801 gcaacctgcg gttagcctcc tagtttgctc tttgattttc attgagtata aatcattcaa
     4861 tgtaaatgaa aaaaattctc aactaaagat aaatcgaaat tagtagatcg tataaagtga
     4921 aaaggaagga tttcaatatg acaagtttaa aattattaaa agaaaaagca cctttggtca
     4981 tttgcatcac caatgatgta gtaaaaaatt tcacagcaaa tggattagta gcactgggcg
     5041 cctcaccagc catgagtgag tttccagaag atttagagga cttattaaag tatgctggtg
     5101 gtttattaat aaacatagga acattgacag atgaaaattg gaaattatac caagctgctc
     5161 tgaaaattgc agagaaatat aatgtcccag cagttttaga tcctgtagcc tgtggagcag
     5221 gagaatatag aaaaaaagta gcagatgatt taatcaacaa ttacaaacta gctgcgatta
     5281 gggggaatgc tggagagatt gcctctttag taggaataga tgtggcatct aaaggagtag
     5341 atagtgcggg agtagataat attgacgaga ttgctctagc agcaaatgag aagttcaata
     5401 ttccaatagt agtaacaggt gaagtggatg ctattgcggt aaatggagaa gtggtaacga
     5461 ttcataatgg tagtgccatg atgccaaaag ttattggaac tggatgttta ttaggagctg
     5521 tagtagcaag ttttatcgga ctggaaaaag gtcaagaatt aaaatcatta gaaacagcaa
     5581 tgttagttta caatatcgct ggagaaatgg cagaaaaacg tccaaatgga catcttcctg
     5641 ggacatttaa agttgaattt ataaatgcct tatacgagat tacagatgaa gatgtaaagg
     5701 aattcaaaag agtgaagtaa gatgtttcat aaagaattac taaaactata ttttatttgt
     5761 ggaacgacta cttgccaagg aaaaaatcta tatacagtcg ttgaggaagc cttaaaaggt
     5821 ggtataacct tatttcaatt tcgagaaaaa ggtgagggtg ctttagaagg cttagaaaaa
     5881 cttgagctag ctatccaaat taaagaactt tgtaaaaaat acaatgttcc atttatcgtt
     5941 aatgacgata tagatttagc aatggaaatt gacgccgatg gcgtacatgt aggtcaagat
     6001 gatattggtg ttgatgaaat tagaaaattg atgccagata aaataattgg tctttctata
     6061 agaaacgaag aagaatttca acaatcaaaa gttgaatatg tagattatgt aggtgttggg
     6121 cctgtatttg atacccagtc aaaagatgat gctggtggtg ctataggtta tgaaggtctt
     6181 gaattgatga gaaaactatt gccacaaatg cctttagttg caattggtgg gatacagacg
     6241 aaacatatta aagacattat aaagaccaat atggatggcg tttcaatcat ttcggcaata
     6301 tcgtatgcaa aaaatataga aaaaactgtt cgggaaatga gtgaacaata gatatctatc
     6361 cttggattct aagtaagtag gattttcctt ttttaaaaag ctatgtccag attcagcttg
     6421 aatggctaat tcatcaaaca ggtcatttgt tttttgcaaa agaaagatct gctgtctttg
     6481 tgagtgcaag gctgtatttc cagttcaatt tcttgaacta gtataaaatg tgtgttataa
     6541 taatcacata attaaataat aaagacattt ggggtgcttt aggctgagat gatacccatt
     6601 gaacctgata cagttaagac tggcgaaggg aaatgtgaaa tgtttttttc gtatgtcgaa
     6661 aagaactgtc taatcttgta agctgaactc taattcgtat ctgtaattag agttttttct
     6721 tttacgaaac tggatgaaga tgatatagta gattgaaata agatgcgaac aaatcaatta
     6781 gaaaattcaa attaatttct agaaatattt tagcattctt gtgtactgtt ctaaattcag
     6841 tctgctatac aaagtattta ggtcggtctt cttgagtgcc ccacttttct ttaaaaaaag
     6901 gagtttttta tgttgaaaaa atggcagtta aaagatgtta tcttgcttgc tttcttgtct
     6961 atcttttttg gtggggtttt cgttggttca ggatatgtgt ataatattct cagtctactc
     7021 ttaacacctc ttggtttgca ggcctttgcc aatgaaatcc tcttcggtct ctggtgtatg
     7081 gctgcgccca ttgctgccat ctttgttccg agagtcggaa gtgcaacgat tggagaagtg
     7141 ctagctgcgc ttgctgaagt cctttatggt agccaatttg gtctaggagc tcttttgtct
     7201 ggcttggttc aaggtttggg aagtgaattt ggttttatcg taactaagaa tcgctatgaa
     7261 agttggctct ctctaactgc taatagtatt gggattacgc ttgttagctt tgtctatgaa
     7321 tacattaagt taggttacta cgccttttcc cttccgtttg tcctttcctt acttgtggta
     7381 cgttttattt ctgtttattt cttctgtacc atcttggttc gtgccattgt caaactctat
     7441 catcagtttg caactggagg aaaagcatag atgggtctgg aactacgagc gattcagtcc
     7501 ccaatcttct ctgagccgtt tgattttact tttcatgcgc aagcctttac cttgttagtt
     7561 gggagtagtg ggtctggaaa atccagcctc tttcaaatga ttgcccaagt cagttctctt
     7621 ccctatagtg gtcaagtcct gatagatggg agcgaggtca gtcaactttc tatcatcgca
     7681 cgtgtccaga aggttggcat tctctttcaa aatcccaatc atcaatttac catggagagc
     7741 ttgtttgagg agctgatttt caccttggag aatatcggct atcaccttca ggaaattgat
     7801 tctaaaatag cagaggttgt ccagcaatgt cgttgcgagg caatcttaca ccgtcccatt
     7861 catcacctat caggtgggga aaagcaaaaa gcagcgctgg ctgtcctctt tgccatgaat
     7921 cctagggtct atctcttgga tgaacctttt gcttccattg accgcaagag cagaatcgag
     7981 atattggaga ttctaaaaga gttggctctt gatggaaaga cagttatttt gtgcgaccat
     8041 gatttatctg actataaagc ctatatcgac catatggttg agctaagaga cggaaaacta
     8101 agggaagtgt ttcaaatccc ttcctatgag atgacacagg ttgcttcaaa ggaagttgct
     8161 tctagcccgg aactattcca tatggataga acgacttgtg agtttggaaa tcgccccctc
     8221 ttttcaattg ctgatttcac attctatcaa gggatttcct gtatcctggg tgacaatggt
     8281 gtcgggaaat caaccctctt tcggtctatt cttcaatttc aaaagtataa ggggcgcatt
     8341 gcatggaagg gttcggtcct gaaaaagaaa aagagtttgt atcgtgatct gactggtgtt
     8401 gttcaggaag ctgagaagca gtttatccga gtcagtctgc gagaggagct tcaattagat
     8461 ggacctgatt ctgaaagaaa tcagcggatt tttcaagctt tacgatattt tgatttggag
     8521 caggcagtcg ataagagtcc ctatcaatta agtggtggtc agcaaaaaat tcttcagctc
     8581 ctgaccatct tgaccagtaa ggcttccgtg atcttgctag atgaaccttt tgcaggtttg
     8641 gatgatagag cctgccatta tttttgcaag tggattgtgg aggagaggaa tcaaggaaga
     8701 agttttctgc tcattagtca tcgtttagac cctttgattt ctgtggttga ttattggatt
     8761 gagatgacta gtcagggtct tcggcatgtg aaagaagtga ccattaccaa accacttaca
     8821 tctcagagta gcaataccca aggggaggtg agatagtatg gtcaaagtag caacccagac
     8881 accgattatc agtctcttct tgctgatttt atccttggaa acatctttca ttccttcgat
     8941 tgctctgaat ctttcggtag tcgcattttg tattctcttt atgctctatt accgtcgatt
     9001 taaaatgtta gcttggatga tcatacttgc cattttacca tcttttgcca actactgggc
     9061 agttcagtta cacggagatg cttcacaggc agtcatgctt ggaacgaggg cctttgtgac
     9121 agtttgtatc ggccttgtct ttgtttcctc tatttcacta aaagagcttc tcttgtactt
     9181 ggctcaaaag gggctatcac gctcttggtc ctatgccttg attgtggtat tcaattcttt
     9241 tcctctcatt cagcaagaaa tcaagtccct caaagaagct tgcctattac gtggtcaaga
     9301 actacatttt tggtcgccct tgatttacag taaggttctg atgacagtct ttaggtggcg
     9361 ccatctttac ctgagagctc tatctgctca cggatatgac gaacatgcac agttgaagaa
     9421 tagctatcgg actttttata ttcctaaaaa aacaaaatta atctacctgc ttttcttttt
     9481 attgcttcaa accagtctat ttttataaag gagttattat ggaatttaca gatattgcga
     9541 tggaattatc caagaaagct tggcaggctt cctttcatca tccctttatt ttacaattac
     9601 aagaggggaa tttagaacct gccattttcc gctattacct gattcaggat gcctactatc
     9661 tgaaggcttt ctcagaaatc tatcatcttt tggctgataa gacttcaaac caagagatga
     9721 aaagactctt gaaacaaaat gctcagggtt tagtggaggg tgagttattt attcgccaac
     9781 aatttttcaa ggaattggaa atcagcgacc aggaaatgga gcaacatcca atcgctccaa
     9841 cctgttatca ttacatttct catatttata ggcaatttgc agaaccgaac ttagccatcg
     9901 cttttgcaag cttgcttcct tgtccttggt tataccatga tataggcaaa tcacttaatc
     9961 ttaaaccatc accaaatcct ctctatcaac aatggattga aacttatatt acggatgagt
    10021 tagagcaaca gatcagagag gagggagcac tggtcaatca gctctatcga gaaagtgatg
    10081 agacagataa gcaaaaaatg ctagatgcct tccacatcag tgttcatatg gaagccaagt
    10141 tttgggagat ggcttaccaa caccagacat ggaagagcga tttacagtct ttagaaaaag
    10201 gagaagaata gaaacatgag aaagcaccaa ctacaagttc acaaattgac cattttatct
    10261 atgatgattg cccttgatgt agtccttaca cctatctttc ggattgaggg aatggcaccg
    10321 atgtccagtg tagtcaatat tctagcggga atcatgatgg gacctgttta tgccttggct
    10381 atggctacag tgacagcctt tatccgtatg acgactcaag ggattccgcc tttagctctc
    10441 acaggagcga cttttggagc ccttctagca ggtctctttt ataagtacgg tcgaaaattt
    10501 tacttttctg ccttgggaga aattgtggga acaggtatta ttggttctat tgtttcctat
    10561 cctgttatgg tactctttac aggatcagct gctaagctta gctggtttat ctacacgcct
    10621 cgatttttcg gagcaacctt gattggtaca gcgatttcct ttattgcctt tcgattttta
    10681 atcaagcagg aattctttaa aaaagtgcag ggatatttct ttagtgaaag gatagactga
    10741 tgcaggaatt tacaaatccc tttcctatag gctctagttc cctcattcac tgtatgacca
    10801 atgagatttc ttgtgagatg ctggcaaatg ggattttggc tctgggatgc aaacctgtca
    10861 tggcagatga tccccgtgag gttcttgatt ttactaagca aagtcaggct ctcttcatca
    10921 atttggggca tttgtcagct gagaaggaga aagcaatccg tatagcagct tcttatgcag
    10981 ctcaagtttg tctcccaatg gtagtagatg cggttggcgt aacagcttca tccattcgta
    11041 agagcttagt cagagacctt ttagactata gacctacggt ccttaaagga aacatgtcag
    11101 aaattcgaag tcttgttgga ttaaagcacc acggcgttgg ggtcgatgcg agtgctaaag
    11161 atcaagaaac ggaggatttg cttcaagtct tgaaagactg gtgtcagacc tatcatggta
    11221 tgtctttctt agtcacaggt cccaaggacc tcgtcgtttc gaaaaatcag gtcgctgtac
    11281 tgggaaatgg ctgtgcagaa ttagactgga taacagggac aggagatttg gttggagcct
    11341 taacagccgt ttttctcagc caaggaaaga ctggttttga agcttcttgc ttagcagtct
    11401 cttatctcaa tatcgctgct gagaaaatag ttgttcaagg aatgggattg gaagaatttc
    11461 gttaccaagt actcaatcag ctttcgctcc taagaagaga tgaaaattgg ctagatacca
    11521 tcaaaggaga ggtttatgaa tagagaagca cttagactat atctggtaac caatcgctat
    11581 caagattccg tggaaagctt tcttgcaaaa gttgagacgg cctgccgttc aggggttacc
    11641 atagtccaat tgcgagaaaa aaatctcaca accaatcaat attatcaact ggcaaaacaa
    11701 gtcaaggaaa taacagatgc ttatcaggta cccttgataa tcgatgatcg gttggatgtt
    11761 tgtcttgcgg ttgatgctgc tggtctgcat attggagatg acgaactccc agtttcggtt
    11821 gcccgacaag tcttgggtcc tgaaaaaatc ctcggtgtca ccgctaaaac ggttaaaaga
    11881 gctctggaag cggagaaatc aggtgcagat tacttgggga caggagccat ttttccgaca
    11941 accaccaagg aaaatgcacc catcaccctg atttcaacct tgaaaacaat ttgccaaacg
    12001 gttgccattc caatagttgc tattggtggc ttgacttcgg agaatattga tcagcttatg
    12061 ggcactggca tagctggtgt agctgttgta cgtgatttga tgcaagcaga agatattgag
    12121 gcaaaaacgc aagccttttt aacaaagttg catgacattc tttcctaatt aatactcaat
    12181 gaaaatcaaa gagtaaacta gaaagctagt cgcaggttgc tcaaagtact gccttgaggt
    12241 tttagataag actgacgaag tcagctcaaa acagtgtttt gaagttgcag atggaagctg
    12301 acgtagtttg aagagatttt cgaagagtat aaaaactctc taattccctt aaagtgggaa
    12361 ctagagagtt tttttcttaa tctttaaaag ttgtatggtt gactggacca gaaccatgac
    12421 cgagttgagg ggcatcttga atagcttttg tgataaaggc cttggcctta tcaactgcct
    12481 ggtaaagact cttgcccttg gctagttcag cagtaatcac tgcagcaaag gtacatccag
    12541 taccatgggt gtgacaggtt tgaattcgtg ggctttccca gacaaattgt tcattcttgg
    12601 taaagaggaa atctttagca ccacctttga gatgtccgcc tttgataacc acagactgag
    12661 gaccaaattc ttttaaaatc aggcgaccag cacgctgcat gtcttcgggg tcatggattg
    12721 aaaaaccaac aatctcttct gcttcaggaa gatttggcgt aataatagtt gctagaggta
    12781 gtaagtttgt tttgagatag tctctagcac ttgagtcaat caaggcatct ccacttgtag
    12841 caaccataac aggatcaagg acatagggac aatccagttt tttaagatag ggttggatga
    12901 tttccatgat ttcagtagta gccaacattc cagtttttac agcctgaggt ggaatatcag
    12961 aaaagacact ctccaattgg gctttcaaca tttgaggaga aacgtgctcg attagctgaa
    13021 cacctctggt attttgagcg acaagactgg ttacaacagc cattccatag acatctctcg
    13081 cttggaatga ctttaaatct gccataatgc cagcaccacc actagggtca gtccctgcaa
    13141 tggtcaaagc aacgggtaaa taagtcatct aaaacctccc aaccaactga agtttgtatt
    13201 cttaagaaca agctagtctg ttttagaaag gcaatagaag actgctagtc cccattatca
    13261 tttccacttc catcagctag cattacctag attgagtcag agggatctaa cagtcgttaa
    13321 tctcagcttt acgcacccct agtggttgtt ttcttttttc tttagtatag catattttta
    13381 ttgtttatat agtaatattt gactgcaaat cgtttttcaa atgattaaaa ttctattttt
    13441 cgaagaaaat attatttcta taattgacaa atgtagattt tgggagtata ctgttgagtg
    13501 taattgacaa atgtagattt tggaggtatg gtaatgcaga tttcagatgc agaatggcag
    13561 gtcatgaaga ttatttggat gcagggggag cagaccagta cagatttgat tagggttttg
    13621 gcagagcggt ttgactggtc caagtccacg gttcagacac ttttggctcg tctagttgag
    13681 aaagagtgtt tgactcggaa aaaagaaggc aagtcctttg tttattcagc gcttttaact
    13741 ctagaccaaa gtcgggattt acttgtccaa gatatcaaag acaaggtttg ttcccgtagg
    13801 attaggaatt tgttggctga cttgattgta gaatgtgaat ttactcagac tgacttggaa
    13861 gacttggaag ctgtgatttc agagaagaaa tcaagtgctg taacagaagt aagatgtaat
    13921 tgtatgtaaa ggagacgtca tgttaaatag tattgtaacc attatttgta ttgcccttat
    13981 cgcgtttatc ttgttttggt ttttcaaaaa gcctgaaaaa tctggacaaa aagcccagca
    14041 aaaaaacgga taccaagaga ttcgagtgga agtcatggga ggctatactc ctgagttgat
    14101 tgtcctcaag aaatcagtgc cagcccgcat tgtctttgac cgcaaggatc cttcaccatg
    14161 tctggatcaa attgtttttc cagattttgg tgtacatgcg aacctgccaa tgggggaaga
    14221 gtatgtagtg gaaatcacgc ctgaacaggc tggagagttt agctttgctt gtggtatgaa
    14281 catgatgcac ggcaagatga ttgtagagta ggtggagact atgacagaaa ttgtgaaagc
    14341 aagcttagaa aatggcattc aaaaaatccg tatccaagct gaaaaaggct atcatccagc
    14401 ccatatccag cttcaaaagg gaattccagc tgagattacc tttcatcgtg ctactccttc
    14461 aaactgttat aaggaaattc tgtttgaaga agaaggtatc ttggaaccaa tcggcgtaga
    14521 tgaggagaaa gtcattcgtt ttacacctca agaattaggg cgacatgaat tttcttgtgg
    14581 catgaagatg caaaagggaa gctatacagt cgttgagaag actcgaaaat ctctatctct
    14641 cctgcaacgt ttttggatta ctagtatctg tactgtgcct cttgtgattc tcatgattgg
    14701 gatgttggca ggtagcatta gtcatcaagt catgcattgg ggaacctttc tagcaacaac
    14761 gcctattatg ttagttgcag gtaagccata tatccagagt gcttgggcca gttttaaaaa
    14821 gcacaatgcc aacatggata ccttggttgc gctgggaact ctagtggctt atttctatag
    14881 cctagttgct ctctttgctg gtctccctgt ttacttcgaa agtgctggat ttatcctctt
    14941 tttcgttctt ttgggagcag tttttgagga aaaaatgaga aaaaatacgt cccaagctgt
    15001 ggagaaatta ctggacttgc aagctaaaac cgcagaagtc ttgagtgatg atagttatgt
    15061 ccaagttcct ttggaacaag tcaaggtagg cgacctgatt cgagtgcgtc ccggtgaaaa
    15121 gattgctgtt gatggtgtcg tagtagaagg tgtctctagt attgacgaat ccatggtgac
    15181 aggtgagagt ctgcctgtgg acaagacagt tggagatact gtcattggct caaccatcaa
    15241 tcatagtgga acgcttgtct ttagagcaga aaaagttggc tcagagactg ttttggctca
    15301 gattgtggat tttgtgaaga aagctcagac aagtcgtgcg ccgattcagg acttgacgga
    15361 taagatttca gggatttttg tcccagtagt tgtcatttta ggaatcatga ccttttgggt
    15421 ttggttcgtc ttgctcaggg atagtgtggt tgtgcttgga gctagctttg tgtcctctct
    15481 tctctacgga gtggcggttt tgattatcgc ctgtccttgt gccttgggac ttgcaacacc
    15541 gacagccctt atggtgggga caggacgtag tgccaagatg ggggttctcc tcaaaaatgg
    15601 aactgtctta caggaaatcc agaaagttca aacccttgtc tttgataaga ccgggacttt
    15661 gacggaaggg aaacctgtgg taacagatgt catcggcgac gaagtagaag tgtttggatt
    15721 ggcagcctcc ttggaagatg cttctcaaca cccactggct gaggctatcg ttaagcgagc
    15781 gagtgaagct ggacttgagt ttcaaactgt tgaaaatttt caggccttgc acgggaaagg
    15841 tgtttcaggg cgaatcaatg gaaaacaagt tttacttgga aatgctaaaa tgctggatgg
    15901 catggatatt tctaatactt atcaagataa actagaagaa ctagaaaaag aagctaagac
    15961 agttgtgttc ttagctgttg acaatgaaat caaaggcttg cttgctttgc aagatattcc
    16021 taagaaaaat gctaagctag ccatcagtca gctaaaaaaa cgtggtctcg ggacagtcat
    16081 gctgacagga gacaatgctg gtgtggcgcg tgctattgca gatcaaatcg gaattgaaga
    16141 ggtcattgca ggcgtcttgc cagaagaaaa agcccatgaa atccataaac tgcaacagtc
    16201 aggtaaagta gcctttgttg gtgatgggat caatgacgct cctgccctta gtgtagcaga
    16261 tgtggggatt gctatgggag ctggaacaga tatcgccatc gagtcagcag atttggtgtt
    16321 gacaaccaat aatcttttag gagtggtgcg tgccttcgac atgagtaaga aaacctttca
    16381 tcgtattctg ctcaatcttt tctgggcttt tatctacaat gttgtcggaa ttccgattgc
    16441 agcaggagtc ttttcaggtg ttggactggc tctcaaccca gaattggcag gtctagccat
    16501 ggcctttagt tctgtatctg ttctgaccag ttcccttctg ttaaatttta gtaaaataga
    16561 ctaaaagtaa tgactagatt tttttgttat aaaacagaaa tgacgacact ttcaaaactg
    16621 tattagaata gagaatagag agttttgagc agatttttag aaaagtcagc ataaatatga
    16681 tacagtggaa tagtaaaaaa ttggagaacg tttccaattc tatgtaatcg tattctccaa
    16741 gtctaaaaaa attgaaggag agttatcatt atgactcaag ggaaaattac tgcatctgca
    16801 gcaatgctta acgtattgaa aacatggggc gtagatacaa tctacggtat cccatcagga
    16861 acactcagct cattgatgga cgctttggct gaagacaaag atatccgctt cttacaagtt
    16921 cgccacgaag agacaggtgc tcttgcagcg gttatgcaag ctaaattcgg cggctcaatc
    16981 ggggttgcag ttggttcagg tggtccaggt gcgactcact tgattaacgg tgtttacgat
    17041 gcagctatgg ataacactcc attcctagca atccttggat cacgtccagt taacgaattg
    17101 aacatggatg ctttccaaga gcttaaccaa aacccaatgt acaacggtat cgctgtttac
    17161 aacaaacgtg tagcttacgc tgagcaattg ccaaaagtaa ttgacgaagc ctgccgtgct
    17221 gcagtttcta aaaaaggtcc agctgttgtt gaaattccag taaacttcgg tttccaagaa
    17281 atcgacgaaa actcatacta cggttcaggt tcatacgaac gctcattcat cgctcctgct
    17341 ttgaacgaag ttgaaatcga caaagctgtt gaaatcttga acaatgctga acgcccagtt
    17401 atctatgctg gatttggtgg tgttaaagct ggtgaagtga ttactgaatt gtcacgtaaa
    17461 atcaaagcac caatcatcac aactggtaaa aactttgaag ctttcgaatg gaactatgaa
    17521 ggtttgacag gttctgctta tcgtgttggt tggaaaccag ccaacgaagt ggtctttgaa
    17581 gcagacacag ttcttttcct tggttcaaac ttcccatttg ctgaagttta cgaagcattc
    17641 aagaacactg aaaaattcat ccaagttgat atcgaccctt acaaacttgg taaacgtcat
    17701 gcccttgacg cttcaatcct tggtgatgct ggtcaagcag ctaaagctat ccttgacaaa
    17761 gtaaacccag ttgaatcaac tccatggtgg cgtgcaaacg ttaagaacaa ccaaaactgg
    17821 cgtgattaca tgaacaaact cgaaggtaaa actgagggtg aattgcaatt gtatcaagtt
    17881 tacaatgcaa tcaacaaaca tgctgatcaa gacgctatct actcaatcga cgtaggtaac
    17941 actactcaaa catctactcg tcaccttcac atgacaccta agaacatgtg gcgtacatct
    18001 ccactctttg cgacaatggg tattgccctt cctggtggta tcgctgctaa gaaagacaat
    18061 ccagatcgcc aagtatggaa catcatgggt gacggagcat tcaacatgtg ctacccagac
    18121 gttatcacaa acgttcaata cgaccttcca gttatcaacc ttgtcttctc aaatgctgag
    18181 tacggcttca tcaagaacaa atacgaagat acaaacaaac acttgtttgg tgtagacttc
    18241 acaaacgctg actacgctaa aattgcggaa gctcaaggag ctgttggatt cacagttgac
    18301 cgtatcgaag acatcgatgc agttgttgca gaagctgtta aattgaacaa agaaggtaaa
    18361 actgttgtca tcgatgctcg catcactcaa caccgtccac ttccagtaga agtacttgaa
    18421 ttggatccaa aacttcactc agaagaagct atcaaagcct tcaaggaaaa atacgaagca
    18481 gaagaactcg taccattccg tctcttcttg gaagaagaag gattgcaatc acgcgcaatt
    18541 aaataattcc tctcgccgaa aatcaaatat gaaacttgta gactttattc tttgattttc
    18601 atagagcaga actttaaaag atcggagcaa tccggtcttt ttatggagga gagtaaatga
    18661 atttaaatca attagatatt atcgtttcaa atgttcccca agtctgtgct gacttggagc
    18721 atattttgga taaaaaggca gattatgctg atgatggttt tgctcagttt acgattggta
    18781 gtcactgcct tatgttgtca caaaatcatt tggttccttt ggaaaacttt cagtcaggaa
    18841 tcattattca tatcgaggtt gaggatgtag accagaacta caaacggttg aacgagcttg
    18901 gtataaaggt tttacacgga ccaactgtaa ccgattgggg aacagagtcc ttattagttc
    18961 aaggacctgc tggtctagtg cttgattttt atcgtatgaa ataggtcgcg tagtcatttg
    19021 acgttaacct tagctatttt
//
LOCUS       DAVLAQ010000033        18381 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000033 DAVLAQ010000000
VERSION     DAVLAQ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.033"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(73..882)
                     /locus_tag="VXB71_001306"
     CDS             complement(73..882)
                     /locus_tag="VXB71_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0451418.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(884..1687)
                     /locus_tag="VXB71_001307"
     CDS             complement(884..1687)
                     /locus_tag="VXB71_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0451419.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VXB71_001308"
     CDS             complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VXB71_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0451420.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3520..4227
                     /locus_tag="VXB71_001309"
     CDS             3520..4227
                     /locus_tag="VXB71_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0451421.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4232..5254
                     /locus_tag="VXB71_001310"
     CDS             4232..5254
                     /locus_tag="VXB71_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0451422.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5271..6140
                     /gene="licA"
                     /locus_tag="VXB71_001311"
     CDS             5271..6140
                     /gene="licA"
                     /locus_tag="VXB71_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0451423.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6130..7008
                     /locus_tag="VXB71_001312"
     CDS             6130..7008
                     /locus_tag="VXB71_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0451424.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7020..7709
                     /locus_tag="VXB71_001313"
     CDS             7020..7709
                     /locus_tag="VXB71_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0451425.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7805..8653
                     /gene="dprA"
                     /locus_tag="VXB71_001314"
     CDS             7805..8653
                     /gene="dprA"
                     /locus_tag="VXB71_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0451426.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9542..10585
                     /locus_tag="VXB71_001315"
     CDS             9542..10585
                     /locus_tag="VXB71_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0451427.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10752..12839
                     /gene="topA"
                     /locus_tag="VXB71_001316"
     CDS             10752..12839
                     /gene="topA"
                     /locus_tag="VXB71_001316"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0451428.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            12945..13304
                     /locus_tag="VXB71_001317"
     CDS             12945..13304
                     /locus_tag="VXB71_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0451429.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13397..14029
                     /locus_tag="VXB71_001318"
     CDS             13397..14029
                     /locus_tag="VXB71_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0451430.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14073..14729
                     /locus_tag="VXB71_001319"
     CDS             14073..14729
                     /locus_tag="VXB71_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0451431.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14748..15380
                     /locus_tag="VXB71_001320"
     CDS             14748..15380
                     /locus_tag="VXB71_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0451432.1"
                     /translation="MNFQLAKYSLLKKFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15408..15842
                     /locus_tag="VXB71_001321"
     CDS             15408..15842
                     /locus_tag="VXB71_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV0451433.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15854..16891
                     /gene="leuB"
                     /locus_tag="VXB71_001322"
                     /pseudo
     CDS             15854..16891
                     /gene="leuB"
                     /locus_tag="VXB71_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            16888..17157
                     /locus_tag="VXB71_001323"
     CDS             16888..17157
                     /locus_tag="VXB71_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0451434.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17161..17520
                     /gene="leuD"
                     /locus_tag="VXB71_001324"
     CDS             17161..17520
                     /gene="leuD"
                     /locus_tag="VXB71_001324"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0451435.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17682..18305
                     /locus_tag="VXB71_001325"
                     /pseudo
     CDS             17682..18305
                     /locus_tag="VXB71_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         5750 a         3175 c         3889 g         5567 t
ORIGIN      
        1 tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag tagtttgtat
       61 aatccccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc actcttgcat
      121 ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt ggtcatattt
      181 tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt taaaggtatc
      241 aactgggaag atttctttca tcccttcctt accgatccca actcctcctt catattgagg
      301 aatgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt agcgaggatt
      361 gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt tgctatcacc
      421 gtgaactgct cgtgattttt tgatataagc tagttgacga agagccacat acttatagct
      481 cttgtcgaca atgctcaagt ctgtaaatcg atcaattggg aagacatcga tgaaaaggct
      541 ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtgt ccaaaatcga
      601 tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt agcgagggtg
      661 attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa gggaaatatc
      721 aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca tggttccata
      781 actgagaaaa taaggaatat catgtttctt acaagtctca tcaatatagt ccagcagggc
      841 tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc tccaatttat
      901 aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc atataatctc
      961 cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa
     1021 agggtaaatc gattgtttta tcaaaggtac cacttgggaa gacttccttt tccttaaatt
     1081 ttgaagggat aaaagccata tactgcccat tttcacgact atatttttga atttctttct
     1141 cgattttatt tgcaaaataa cgaggagaaa ctggtcgaag gagcaaccaa aaggctgttc
     1201 gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta ctgaaagaca
     1261 gcagtttgaa gctttccagt ttataacaag tatcaatgac cttaggatca tcaaagcgat
     1321 ccatagggaa aatatcgata aagataccag actcataggt ttttgtattt cgagtatcaa
     1381 taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc ttatcagttt
     1441 ctaaggatag gagttcatac ttgctttttt ccttttgaaa aatgttaata aatcgttggt
     1501 agtcttctct aggcatggat aaatcaatat cgtcgtccca agggataaag ccctcatgtc
     1561 gaaccgcccc aatcagagta ccgtagttaa taatatagtt gatattgtgc tttttacaga
     1621 gagtatcaat ataatccaaa atttctaatt caatttgttt ggcatcttca acggttagtt
     1681 gtttcatttt aaactcctat gattttttaa atttattttt taaggctaga acatggttta
     1741 aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa gagatagctg
     1801 atagcaagat aatcaaacca gtattaatca aaaatggcaa attaatgacc atatccacag
     1861 gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag agagagtatc
     1921 gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg atgaaaatga
     1981 tatagaaaac aagtagagaa gcctctgata acatagttgt cagtaagtag tattcgggag
     2041 ccacgatacg gttgaaaaag aggagactat tcaagcccaa attgagtagc ccagcaaaga
     2101 ctgtataaac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg gaaccaagaa
     2161 tggtatctaa ggccaggata atcgtacgaa aagcgaagag agaggtcaag atgccgcctc
     2221 cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc atgagtccaa
     2281 aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc agagaaacat
     2341 aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc actccaattg
     2401 cacctgttac aaccccagct ataacggtca caattcgctg agctatggta tagtaactaa
     2461 cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg aagagcatat
     2521 tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta aaatcactta
     2581 ggtgaatctt aacaagtttg atgtctcttt taatccaaaa ataactaatc aggtagttaa
     2641 tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca tttttaacaa
     2701 ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa aagagaaaac
     2761 tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca atgagttgaa
     2821 tccccataac aaggtagacc tttttgatga ttggattatc agtaaagaag agaggatagg
     2881 ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa aaaagactag
     2941 aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc cttaaaccgt
     3001 agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg tcgactgagt
     3061 tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca gttaggatgg
     3121 gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat tttatacttt
     3181 tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga aatgaagggc
     3241 agtaagccaa gcaatcactt tgaagtttca aatcttaaat tttaagtttt ctttaaggaa
     3301 agtatattat tctgaaggac tctaaaattt cgcagtcatt tattagtaat tgctacagaa
     3361 ttcctagtca ttactagaaa tggactagtt tctttgaata atagaactgc ataattctcc
     3421 tattctagaa ggggaggacc agtatttctt ttatgatagg actagattgt ggtataatag
     3481 agagaataag tttttttagt aagacaaagg agaaaataga tgatttatgc aggaattctt
     3541 gccggtggaa ctggcacacg catggggatc agtaacttgc caaaacaatt tttagagcta
     3601 ggtgatcgac ctattttgat tcatacaatt gaaaaatttg tcttggagcc aagtattgaa
     3661 aaaattgtag ttggtgttca tggagactgg gtttctcatg cagaagatct tgtagataaa
     3721 tatcttcctc tttataagga acgtatcatc attacaaagg gtggtgctga ccgcaataca
     3781 agtattaaga aaatcattga agccattgat gcttatcgtc cgcttactcc agaggatatc
     3841 gttgttaccc acgattctgt tcgtccattt attacacttc gcatgattca ggacaatatc
     3901 caacttgccc aaaatcatga cgcagtggac acagtggtag aagcagttga tactatcgtt
     3961 gaaagtacca atggtcaatt tattacagat attccaaatc gtgctcacct ttatcaagga
     4021 caaacacctc aaacattccg ttgcaaggac ttcatggacc tttatggatc tctttctgat
     4081 gaagagaagg aaatcttgac agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg
     4141 gccttggcca aaggtgaata ctcaaatctg aagattacaa ccgtaacaga tttgaagatt
     4201 gcaaaaagta tgattgagaa agactagtaa aatgattaat caaatttatc aactaactaa
     4261 gcctaagttt atcaatgtca aatatcagga agaggctatt gaccaagaga atcatatcct
     4321 tatccgtccc aactacatgg ctgtctgtca tgcggatcag cgttactatc agggaaaacg
     4381 tgatcccaag attttgaata aaaagcttcc aatggcaatg attcacgagt catgtggaac
     4441 cgtcatttct gacccgaccg gaacctacga ggttggtcaa aaagttgtca tgattcccaa
     4501 tcagtctcct atgcagagtg atgaagaatt ctatgaaaac tacatgacag ggacccattt
     4561 cttgtctagt ggatttgatg gctttatgag agagtttgtt tctctcccta aagatcgtgt
     4621 ggtggcttat gatgctattg aagatacggt tgcagccatt acagagtttg tcagtgtggg
     4681 catgcacgct atgaatcgtc tattgactct tgctcatagc aagcgggagc ggatcgccgt
     4741 tattggagat ggaagtttag cttttgtggt tgccaatatt atcaactata ctttgccaga
     4801 atcagagatt gtggttattg gtcgtcattg ggaaaagttg gaactcttct catttgccaa
     4861 agaatgctat attacggata atattcctga agagttggcc tttgaccatg cttttgaatg
     4921 ttgtggtggt gatggtactg gaccagctat taatgacttg attcgctaca ttcgtcctca
     4981 gggaacgatt ctcatgatgg gagttagcga atataaagtc aatctcaata ctcgcgatgc
     5041 cttagaaaag ggcttgattt tggttgggtc atctcgttct ggtcgcattg attttaaaaa
     5101 tgctatccaa atgatggaag tcaagaaatt tgccaatcgt cttaaaaata tcctttatct
     5161 agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac
     5221 agcctttaaa acagtgttta agtgggaagt ataagtactg gaggttaatt gtggagaaaa
     5281 tcattaaaga aaaaatttct tccttactta gtcaagaaga ggaagtcctc agtgttgaac
     5341 aactgggtgg aatgaccaat caaaactatt tggccaaaac aacaaataag caatacattg
     5401 ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg acaagatgaa aagtacaatc
     5461 ttgaactact aaaggattta ggcttagatg taaaaaatta tctttttgat attgaagctg
     5521 gtatcaaagt aaatgagtat atcgaatctg cgattacgct tgattcaacg tcaatcaaga
     5581 ccaagttcga caaaattgct ccaatattac aaactattca tacgtctgct aaggaattaa
     5641 gaggagaatt tgctcctttt gaagaaatca aaaaatacga atccttgatt gaagaacaaa
     5701 ttccttatgc caactatgaa tctgttagaa atgcagtctt ctccttagag aaaagactgg
     5761 ctgacttagg tgttgacaga aaatcttgtc atatcgattt ggtgcctgaa aactttatcg
     5821 aatcacctca aggacgactt tatttgattg actgggaata ttcatcaatg aatgatccaa
     5881 tgtgggattt ggctgccctc tttttagagt ctgaattcac ttcccaagag gaagaaactt
     5941 tcttatctca ctatgagagt gaccaaacac cggtttctca tgaaaagatt gctatttata
     6001 aaattttaca agatactatt tggagtctat ggactgtcta taaggaagag caaggtgaag
     6061 attttggtga ctatggtgtg aatcgttacc aaagagctgt taaaggtttg gcttcttatg
     6121 gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc ttctctcagg tattttctgg
     6181 ggcttgggtc taacggttag tgcttatatc ttttcgattt ttacagattt gtcacccttt
     6241 gtggtggctg cagctcatga ttttttgagc atctttatct tactagcttt tctcttggta
     6301 aaagaaggga aagttcgcct ctcaattttc ttaaatattc gcaatgtcag tgttatcatc
     6361 ggagccttgc tagcaggccc tatcggtatg caggccaatc tttatgcagt taagtatatc
     6421 ggaagttctt tagcttcatc tgtatcggct atttaccctg cgatttcagt tctattggct
     6481 ttcttctttt tgaagcacaa gatttcgaaa aatactgtat ttgggattgt cttgattatt
     6541 ggagggatta ttgctcagac ctataaggtt gaacaggtta attctttcta cattgggatt
     6601 ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc
     6661 atggaaagtg aattgagtga aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg
     6721 tcctatcttg tgattgtgct cttctctcat cagtcattta ctgcagtagc caatggacaa
     6781 ttgctaggtc tcatgattgt ttttgcagcc tttgatatga tttcctactt ggcttattat
     6841 atcgctatca atcgcttgca accagccaag gctacaggct tgaacgtgag ctatgtagta
     6901 tggacggtct tgtttgcagt tgttttcttg ggtgcaccgc tagatatgct gaccattatg
     6961 acgtcacttg tcgtcattgc tggagtttat attattatta aagaataaag gagattcgtg
     7021 tgaaagccat tatcttagca gcgggattgg gaactcgctt gcgtcctatg actgaaaata
     7081 cccctaaagc cttggttcag gttaatcaaa aacctttgat tgagtaccaa attgagtttc
     7141 tcaaagaaaa aggaatcaat gacatcatca tcattgttgg ttatcttaaa gaacaattcg
     7201 attacttgaa agagaaatac ggtgttcgtc tcgttttcaa tgataaatac gctgactaca
     7261 ataactttta ctctctctat cttgtaaaag aagaattggc caacagctat gttattgatg
     7321 ctgacaatta tctctttaaa aatatgttcc gcaatgattt gacacgttcg acttatttta
     7381 gtgtttatcg tgaagattgt accaacgaat ggttcttggt ttatggagat gactacaagg
     7441 ttcaagacat tattgttgat agcaaggcag gtcgcatcct tagtggtgta tccttctggg
     7501 atgctccaac tgcagaaaag attgtcagct ttatcgacaa ggcttatgta agtggtgaat
     7561 ttgttgatct ctattgggac aatatggtta aggataatat caaagagcta gatgtctatg
     7621 ttgaagaatt agaaggcaat agcatttatg agatcgatag tgtccaagac tatcgtaaat
     7681 tagaagaaat tcttaaaaac gaaaattaaa gattccaaca tctgacaaaa tagtcggatg
     7741 ttttttgatt ttttacgaac ttttacgaat agatagatga gtagaaaaag aaatggagtt
     7801 atttatgaaa atcacaaact atgaaatcta taagttaaaa aaatcaggtt tgaccaatca
     7861 acagattttg aaagtgctag aatacggtga aaatgttgat caggagcttt tgttgggtga
     7921 tattgcagat atctcaggtt gccgtaatcc agccgttttt atggaacgtt attttcagat
     7981 agacgatgcg catttgtcga aagagtttca aaaatttcca tctttctcta ttttagatga
     8041 ctgttatcct tgggatttga gtgaaatata tgatgcgcct gtacttttat tttacaaggg
     8101 aaatcttgac ctcctgaaat tcccgaaggt agcggtcgtg ggcagtcgtg cttgtagcaa
     8161 acagggagct aagtcagttg aaaaagtcat tcaaggcttg gaaaatgaac tggttattgt
     8221 cagtggtctg gccaagggca ttgacacagc agctcatatg gcagctcttc agaatggcgg
     8281 aaaaaccatt gcagtgattg gaacaggact ggatgtgttt tatcctaaag ccaataaacg
     8341 cttgcaagac tacatcggca atgaccatct ggttctaagt gaatatggac ctggtgaaca
     8401 acctctgaaa tttcattttc ctgcccgtaa tcgcatcatt gctggacttt gtcgtggtgt
     8461 gattgtagca gaggctaaga tgcgttcagg tagtctcatt acgtgtgagc gagcaatgga
     8521 agaaggacgc gatgtctttg ctattcctgg tagcatttta gatggactat cagacggttg
     8581 ccatcatttg attcaagaag gagcaaaatt agtcaccagt gggcaagatg ttcttgcgga
     8641 atttgaattt taaaaatgac ctaagctaga attctaagaa aaaatcaatt ttaagagaaa
     8701 atgaacccaa catttccata ataaaacgca tattagcaag tttttaacac ttgataatat
     8761 gcgttttttc taagtggatt agtagagtag aggatttttc tcatataata ctcttcgaaa
     8821 atctcttcaa actacgtcag cttccatctg caacctcaaa acagtatttt gagctgactt
     8881 cgtcagtctt atctacaacc tcaaagcagt gctttgagca acctgtggct agcttcctag
     8941 tttgcgcttt gattttcatt gagtataagg gaaagtatag tgaattgaaa taagatgtga
     9001 acaactctat caggaaagtc aaattgattt atagaaatat tttagcagcc aaggtgcact
     9061 gttatagatt caatacacta taatttagtg taattgagaa aggagaaatg attgtgattg
     9121 atgttggcta ggttatgttc aatgattcct accgtctcaa atcttgtcag taaggaaaaa
     9181 taaattcttc aaaagtagag attacaaggc ttgtttaaga aagaattcaa agaccttgac
     9241 aaataaaaat aaaatggtta ttataaaaaa tggtctgaaa tagatgatga tacttttcga
     9301 aaatctcttc aaactacgtc agctcagctt tgccttgctg tgttttgagc aagctacggt
     9361 tagcttccga gtttgatttt catttactag aaatgaaact gatgagagat atcagtagac
     9421 atttgagtca ggatattatg gaaaatgata aaaagagctc gtgagattgg catatcagac
     9481 tactaaagta ttgagtttgt taggatttta gcgactagtt agctgggaaa ggaagatatt
     9541 tgtgacaaat aataaactgt attcgttgat agaatttaga aataaaatat atgaagaatt
     9601 agaactttcc agaagtgatt tagcgatttt actatgtgcc atgcttatcg cctctatcgg
     9661 attaaatatg gattcgactc ccgtgattat tggagccatg ttaatctctc ctttgatgac
     9721 acctattctg ggagtggggc tctctctagc tatatttgat tttaaattgt taagaaaatc
     9781 ttttaaaata ttagctattc aaattcttgc cagtctaata gcttcaacac tttattttta
     9841 tctttctccc atttcgtatg ctagttcgga gattgttgct agaacctctc cgactatttg
     9901 ggatgttctc attgcttttg taggagggat agcaggtatt attggtgcta ggaaaaaaga
     9961 gaccaataat attgttcctg gtgttgctat tgcaaccgcc ttgatgcctc ctctttgtac
    10021 agtaggttat gctattgctt ctgctaatct aaaatttatc ataggctcct cttacctatt
    10081 cctcatcaat tgtagcttta ttgtcattgc gacttatata ggtgttaggt tgatgatggt
    10141 taagaaacat tattttaaag ataatgaaga agactctaaa atgcgtagga ttttgcttct
    10201 agttgctgtt ttgctgatga ttccgagttt catctctgca acgactttag tgagagaaac
    10261 gttgaaaaaa gagtccctta agaaatttat atcagagcag tttcaggggt ataatatttt
    10321 gaaaaaaacc tattctaaaa agactcatac cctaaagcta accatttcag gaaattattt
    10381 gacagaagaa gaactcgata tgatttcaag taagagaggt gactatggtt taagtgatgt
    10441 ttctgttcaa gtttcacaat tgtctgattc agaacaactt agtaaggaag agctggtgga
    10501 gtatttcttc cagtatatca aggataagga agcaaaagaa aaggagaaag ccaataaatt
    10561 tgatacagag tctgaggagc aataatttct tgagaatagc tggtttctct cgtgagtctt
    10621 ctatgtatat caaaggaaga ctgaggtttt aagtataaaa cttttcttct attatagtag
    10681 ctaagtcttg acagggttca aaaaatggtt tacactttat aaagtttatt actttgaaaa
    10741 ggtgtgatac tgtggctacg gcaacaaaaa agaaaaaatc aacagttaaa aaaaatctag
    10801 tcatcgtgga gtcgcctgct aaggccaaga cgattgaaaa atatctaggc agaaactaca
    10861 aggttttagc cagtgtcggg catatccgtg atttgaagaa atccagtatg tccgtcgata
    10921 ttgaaaataa ttatgaaccg caatatatta atatccgagg aaaaggccct cttatcaatg
    10981 acttgaaaaa agaagctaaa aaagctaata aagtttttct cgcgagtgac ccggaccgtg
    11041 aaggagaagc gatttcttgg catttggccc atattctcaa cttggatgaa aatgatgcca
    11101 accgtgtggt cttcaatgaa atcaccaagg atgcagtcaa aaatgctttt aaagaacctc
    11161 gtaagatcga tatggacttg gtcgatgccc aacaagctcg tcggatcttg gatcgcttgg
    11221 tagggtattc gatttcgcct attttgtgga agaaggtcaa gaagggcttg tcagcaggtc
    11281 gcgttcagtc cattgccctt aaactcatca ttgaccgtga aaatgaaatc aatgccttcc
    11341 agccagaaga atactggaca gttgatgctg tctttaaaaa gggaaccaaa caatttcatg
    11401 cttccttcta tggagtagat ggtaaaaaga tgaaactgac cagcaataac gaagtcaagg
    11461 aagtcttgtc tcgtctgacg agtaaagact tttcagtaga tcaggtggat aagaaagagc
    11521 gcaagcgcaa tgctccttta ccctatacca cttcatctat gcagatggat gctgccaata
    11581 aaatcaattt ccgtactcga aaaaccatga tggttgccca acagctctat gaaggaatta
    11641 atatcggttc tggtgttcaa ggtttgatta cctatatgcg taccgattcg actcgtatca
    11701 gtcctgtagc gcaaaatgag gcggcaagct tcattacgga tcgttttggt agcaagtatt
    11761 ctaagcacgg tagcaaggtc aaaaacgcat caggtgctca ggatgcccat gaggctattc
    11821 gtccgtcaag tgtctttaat acaccagaaa gcatcgctaa gtatctggac aaggatcagc
    11881 ttaagctata tacccttatc tggaatcgtt ttgtggctag ccagatgaca gcggccgttt
    11941 ttgataccat ggctgttaaa ttgtctcaaa aaggggttca atttgctgcc aatggtagtc
    12001 aggttaagtt tgatggttat cttgccattt ataatgattc tgacaagaat aagatgttac
    12061 cggacatggt tgttggagat gtggtcaaac aggtcaatag caaaccagag caacatttca
    12121 cccaaccgcc tgcccgttat tctgaagcaa cactgattaa aaccttagag gaaaatgggg
    12181 ttggacgtcc atcaacctat gcgccaacca ttgaaaccat tcagaaacgt tattatgttc
    12241 gcctggcagc caaacgtttt gaaccgacag agttgggaga aattgtcaat aagctcatcg
    12301 ttgaatattt cccagatatc gtaaacgtga ccttcacagc tgaaatggaa ggtaaactgg
    12361 atgatgtcga agttggaaaa gagcagtggc gacgggtcat tgatgccttt tacaaaccat
    12421 tctctaaaga agttgccaag gctgaagaag aaatggaaaa aatccagatt aaggatgaac
    12481 cagctggatt tgactgtgaa gtgtgtggca gtccaatggt cattaaactt ggtcgttttg
    12541 gtaaattcta cgcttgtagc aatttcccag attgccgtca tacccaagca atcgtgaaag
    12601 agattggtgt tgagtgtcca agctgtcatc agggacaaat tattgagcga aaaaccaagc
    12661 gtaatcgcct cttctatggt tgcaatcgct atccagaatg tgaatttacc tcttgggaca
    12721 agcctgttgg tcgtgactgt ccaaaatgtg gcaacttcct catggagaaa aaagtccgtg
    12781 gtggtggcaa gcaggttgtt tgtagcaaag gcgactacga ggaagaaaag attaaataag
    12841 aggaggggcc cgaaagtaaa tttcaggctc cttttggtta gaacttgaca aaatacatca
    12901 ttttatgcga aactagaaga agattatttt aactaggaga agttatgcgt cttatctatc
    12961 tgataattgg ttttttatca ctggccttgg ctattgttgg ggttgtttta cccttgttgc
    13021 ctacaacacc tttccttttg ttgtctattg cttgtttctc cagaagttcc aagcgattcg
    13081 aagactggct ttatcatacc aagctctatc aaacatatgt agctgatttt cgcgagacta
    13141 agtctattac gcgtgaacga aagaaaaaaa tcatcgtatc catttacatt ttgatgggga
    13201 tttctattta ttttgcccct ctcttaccag tcaaaatcgg tctgggtgct ttgaccatct
    13261 ttatcactta ttatctcttc aaggtcattc cagacaaaga atagttaaaa cagtagttat
    13321 ttaccttgat aaaattgaaa gcatattcat aacaatatga tataataaat ttgaagtaat
    13381 attcaaggag aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt tacttgaaaa
    13441 agcgatgcag gctggagctc gtcggattga actctgtgat aatctagcag ttggtgggac
    13501 aacacctagc tatggagtga ctaaggcagc ggttgaactg gcagctaact acgatacaac
    13561 catcatgacc atgattcggc cacgtggtgg tgactttgtc tataatgacc tagaaattgc
    13621 tatcatgcta gaagacattt gtttgactgc tcaggctgga agtcaagggg ttgtatttgg
    13681 agctttaact gctgataaaa agttggataa gcctaatctg gaaaagttaa ttgctgcatc
    13741 aaaaggaatg gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc
    13801 ggaagctatt gactggctca gtcaagccgg tgtcactcgt atcctaactc gtgctggtgt
    13861 gtctggcgac tccttagaaa aacgttttgt tcactatcac agaattttgg agtacgctaa
    13921 aggtaaaatt gaaattctac caggtggggg gattgacctt gacaaccgtc aaacctttat
    13981 tgaccaggtg ggggtaacac aattgcatgg tactaaggtt gttttttaaa aaatagaaag
    14041 gaactgctag ccttgggtag cagttttcac ttatgtttga aatttttaaa tcctatcaat
    14101 ttaatcaaga aaaggctcat gattatggtt ttatagaaaa tagcgaagtc tggacatata
    14161 gttgccagat tttgcaaggt gactttgtca tgactgtgtc catcactgct gataatgtga
    14221 actttcaagt ctttgaccaa gagactggtg acctctatcc tcacgttcat atggaaagca
    14281 tgaggggaag ttttgtcgga aatgtccgtg aggcttgtct ggagattctt taccagattc
    14341 ggaaggcttg ttttgatgtg caagatttta tctgtcatca gactaagcgt atcatgactc
    14401 aagttcagga aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg cctgatacag
    14461 ctgtattgcg ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga
    14521 ataagctgga aaagggcaga gaaggacaag tggaagcagt caacctcaag catgaccaag
    14581 tagctaattt gctttcacaa aaggggattt atccagcctt ccatatgagc aagcgctact
    14641 ggattagtgt gtcccttgat gatactttat cagatgaaga agtactggaa ttgatagaaa
    14701 aaagttggaa cttaacctct aaaaaatgaa atattttaat aattttcatg aactttcaat
    14761 tagctaaata ttctttactg aagaaatttt tagaaaatat aggatttacc acactagagg
    14821 aatatggtgc catcttcaaa tacctgattg agaatgtcaa gacggatcgt cagatcatct
    14881 gttcgcctca ctgtcatgat gacctcggaa tggcagtggc aaatagcctt gctgctgtca
    14941 agaatggtgc aggacgtgtt gaagggacta tcaatggtat tagggagcga gctgaaaatg
    15001 ctgctttgga agaaattgca gtggctctca atattcgcca agattactac caagtagaaa
    15061 ccagtattgt cctaaatgag accatcaata cgtcagaaat ggtttctcgc ttctctggta
    15121 ttccagttcc taaaaacaaa gccgtcgttg gtggcaatac cttctcccac gaatctggta
    15181 ttcaccaaga tggagtcctt aaaaatcctc tcacttatga gatcatcaca cctgaattgg
    15241 ttggtgttaa gattccgctt ggaaaattat ctggtcgcca tgcttttgtt gagaaactga
    15301 gagaattggc cctagatttt acagaagagg atatcaaacc actctttgct aagttcaagg
    15361 cactggccga taagaagtaa gaaatcacag atgcagatcc tcgagctttg gtagctggaa
    15421 ccatggttga aaatccagaa ggcttccact ttgatgattt acaacttcaa actcatgcag
    15481 ataatgacat tgaagcgctc gttagcctag ccaatatgga tggtgagaaa gtcgaattta
    15541 atgcgacagg gcaaggttcc gttgaagcaa tctttaacgc tatcgataag ttctttaacc
    15601 aatctgttcg tttggtgtcc tacactatca atgcggtaac agatggaatc gatgcccagg
    15661 atcgggtttt ggtcactgtt gaaaacagag atacagaaac catctttaat gcagcagggc
    15721 ttgattttga tgtgttgaag gcttctgcta ttgcctatat aaacgctaat acctttgttc
    15781 aaaaagagaa tgcaggtgag atgggacgca gtgtttctta ccacgatatg cctagtgtgt
    15841 aaaggagaag gctatggcaa agaaaatagt agctctagta ggagacggaa ttggcccaga
    15901 aatcatgtag gctggtttag aagttctgga ggctctagct gaaaaaacag gttttgacta
    15961 tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcaggac ctcccttacc
    16021 tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagcag ctatcggtag
    16081 tcctcagtat gatggagcag cggttcgccc tgaacaaggc ctgatggctc tccgtaagga
    16141 actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca agtatttgtc
    16201 accactcaaa ccggaacgaa tttctggtgt agactttgtc gtggtgcgtg aattgacagg
    16261 cgagatttac tttggagatc atattcttga agagcgcaaa gcgcgtgata tcaacgacta
    16321 tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa gaaatcgcag
    16381 aaaaatcgtt actagtatcg ataagcaaaa tgttctagcg acctcaaaac tctggcggaa
    16441 agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacacc agctggtaga
    16501 ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg taacggagaa
    16561 tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac ttgaggttat
    16621 gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc acggttcagc
    16681 acctgatatt gcaggtcaag gaattgccaa tcctacttcc atgattttat cagttgccat
    16741 gatgttgaga gatagtttcg gacgttatga ggatgcagag cgtatcaaac atgctgttga
    16801 gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt caacaaagga
    16861 aatgacggaa gctattattg caaggttatg aagttagacg aaaaaattac tctagtcctt
    16921 ttgatttgga atgtcatcat tttcttgatt tatggcattg acaaattcaa ggcaagaaga
    16981 agaacttggc gcatccaaga gaaaatctta ctcattttag cccttacttg tggtggtttt
    17041 ggggcctggt tagctggaat cacttttcac cacaagactc gaaaatggta ctttaaaaca
    17101 gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg gaggtaatgg
    17161 atggcagggt cttcgaggga acacgctgct tgggttctag cggactatgg ttttaaggtc
    17221 gtgattgcag gatctttcgg tgacattcat tacaataatg aactcaataa tggcctgttg
    17281 ccaatcgttc agcctagaga ggttagagag aaactagccc agctaaaacc aaccgaccag
    17341 gtaactgtgg acttggaaca acaaaaaatc atctcaccag ttgaagaatt caccttcgag
    17401 atagatagcg agtggaaaca taaactccta aatagtttgg atgatatcgg tattaccttg
    17461 cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg gcaggattag
    17521 aaaaaataga aaaggaaata tagtaaactg aaataagatg taaacaaatg aattagagct
    17581 taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga ttcaacacat
    17641 tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa ggtgagggcg
    17701 gatgtatcgt ttgccctact aaagttggtt acattatcat gaccagcaac aaggcaggac
    17761 ttgagcgtaa gttcgcagcc aaagaacgta agcgtaacaa accaggtgtt gttctctgcg
    17821 gtagcatgga tgaacttcgc gctttagcgc aactcaaccc agaaattgaa gcattctact
    17881 aaaaacattg gatgaagata ttcttcttgg ttgtatcctt ccttggaaac cagaagcctt
    17941 tgaaaaactc aaagcatacg ggaatggccg tgaagaactt atgactgatg tacgtggtac
    18001 tagctgtttt gttatcaagt ttggaaaagc aggtgaacaa ttggctgcca agctttggga
    18061 agaaggtaaa atggtctacg cctcatatgc ttcaatgaca aaacgattga aactcgctat
    18121 gagagcaagg tgtaatggtg tctatggtcg ataaggacgg caaactcatc ccagaacaag
    18181 gaggagcacg ttcaacttca ccagcaccag ttgtgatccg taaagggctt gacattgata
    18241 aaatcatgat gcacctgtca gatactttta actcatggga ctaccgtcag gttgagtatt
    18301 attaagataa aaaaagaagt ctagtgttat gagatattaa agctcctaac actggacttt
    18361 ttgtttagaa tttcttttct t
//
LOCUS       DAVLAQ010000034        18367 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000034 DAVLAQ010000000
VERSION     DAVLAQ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18367
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.034"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            402..2555
                     /locus_tag="VXB71_001326"
     CDS             402..2555
                     /locus_tag="VXB71_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0451436.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKANMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2568..3917
                     /locus_tag="VXB71_001327"
     CDS             2568..3917
                     /locus_tag="VXB71_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0451437.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4087..4794
                     /locus_tag="VXB71_001328"
     CDS             4087..4794
                     /locus_tag="VXB71_001328"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0451438.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            4851..8576
                     /locus_tag="VXB71_001329"
     CDS             4851..8576
                     /locus_tag="VXB71_001329"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0451439.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8669..10111
                     /locus_tag="VXB71_001330"
     CDS             8669..10111
                     /locus_tag="VXB71_001330"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0451440.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10148..11170
                     /locus_tag="VXB71_001331"
     CDS             10148..11170
                     /locus_tag="VXB71_001331"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0451441.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11167..11712
                     /gene="purN"
                     /locus_tag="VXB71_001332"
     CDS             11167..11712
                     /gene="purN"
                     /locus_tag="VXB71_001332"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0451442.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            11796..12305
                     /locus_tag="VXB71_001333"
     CDS             11796..12305
                     /locus_tag="VXB71_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0451443.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12330..13877
                     /gene="purH"
                     /locus_tag="VXB71_001334"
     CDS             12330..13877
                     /gene="purH"
                     /locus_tag="VXB71_001334"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0451444.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            13999..15261
                     /gene="purD"
                     /locus_tag="VXB71_001335"
     CDS             13999..15261
                     /gene="purD"
                     /locus_tag="VXB71_001335"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0451445.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15664..16152
                     /gene="purE"
                     /locus_tag="VXB71_001336"
     CDS             15664..16152
                     /gene="purE"
                     /locus_tag="VXB71_001336"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0451446.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16139..17212
                     /gene="purK"
                     /locus_tag="VXB71_001337"
     CDS             16139..17212
                     /gene="purK"
                     /locus_tag="VXB71_001337"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0451447.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            17235..>18367
                     /locus_tag="VXB71_001338"
     CDS             17235..>18367
                     /locus_tag="VXB71_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0451448.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDK"
BASE COUNT         5237 a         3588 c         4426 g         5116 t
ORIGIN      
        1 gtctattata aatagttttt agaaatacta aaattttttt ctttacttaa taatgatatg
       61 aaatcatttc ggttttgtta acttgtaatt cttatatttt ctaggtagaa cgtttgttct
      121 gcctattttt ttatccaaaa agtgcagttg ggagggagat aggctcattt gggaaggaag
      181 tccagttttt gtttagtgat tggggtaaga tagttgttat cagatgagtt tatactcttc
      241 gaaaatcaaa ttcaaaccac gtcaacgtcg ccttgccgta tatatgtgac tgacttcgtc
      301 agtcctatct acaacctcaa aacagtgttt tgagcagcct gcggctagtt tcctagtttg
      361 ctctttgatt ttcattgagt attagggaaa aggagatgaa tatgaaattt gggaaacgtc
      421 actatcgtcc gcaagtggat cagatggact gcggtgtagc ttcattagcc atggtttttg
      481 gctactatgg tagttattat tttttggctc acttgcgaga attggctaag acgaccatgg
      541 atgggacgac ggctttgggc ttggtcaagg tggcagagga gattggtttt gagacgcgag
      601 ccattaaggc gaatatgacg ctttttgact tgccggattt gacttttcct tttgttgccc
      661 atgtgcttaa ggaagggaaa ttgctccact actatgtggt gactgggcag gataaggata
      721 gcattcatat tgccgatcca gatcccgggg tgaagttgac taaactgcca cgtgagcgtt
      781 ttgaggaaga atggacagga gtgactcttt ttatggcacc tagtccagac tataagcctc
      841 ataaggaaca aaaaaatggt ctgctctctt ttatccctat attagtgaag cagcgtggct
      901 tgattgccaa tatcgttttg gcaacactct tggtaaccgt gattaacatt gtgggttctt
      961 attatctgca gtctatcatt gatacctatg tgccagatca gatgcgttcg acactaggga
     1021 ttatttctat tgggctagtc atcgtctaca tcctccagca aatcttgtct tacgctcagg
     1081 agtatctctt gcttgttttg gggcaacgct tgtcgattga cgtgattttg tcctatatca
     1141 agcatgtttt tcacctccct atgtccttct ttgcgacacg caggacaggg gagatcgtgt
     1201 ctcgttttac agatgctaac agtatcatcg atgcgctggc ttcgaccatc ctttcgattt
     1261 tcctagatgt gtcaacggtt gtcattattt cccttgttct attttcacaa aataccaatc
     1321 tctttttcat gactttattg gcgcttccta tctacacagt gattatcttt gcctttatga
     1381 agccgtttga aaagatgaat cgggatacca tggaagccaa tgcggttctg tcttcttcta
     1441 tcattgagga catcaacggt attgagacta tcaagtcctt gaccagtgaa agtcagcgtt
     1501 accaaaaaat tgacaaggaa tttgtggatt atctgaagaa atcctttacc tatagtcgag
     1561 cagagagtca gcaaaaggct ctgaaaaagg ttgcccatct cttgcttaat gtcggcattc
     1621 tctggatggg ggctgttctg gtcatggatg gcaagatgag tttggggcag ttgattacct
     1681 ataatacctt gctggtttac tttaccaatc ctttggaaaa tatcatcaat ctgcaaacca
     1741 agcttcagac agcgcaggtt gccaataacc gtctaaatga agtgtatcta gtagcttctg
     1801 agtttgagga gaagaaaaca gttgaggatt tgagcttgat gaagggagat atgaccttca
     1861 agcaggttca ttacaagtat ggctatggtc gagacgtctt gtcggatatc aatttaaccg
     1921 ttccccaagg gtctaaggtg gcttttgtgg ggatttcagg gtcaggtaag acgactttgg
     1981 ccaagatgat ggttaatttt tacgacccaa gtcaagggga gattagtctg ggtggtgtca
     2041 atctcaatca gattgataaa aaagccctgc gccagtacat caactatctg cctcaacagc
     2101 cctatgtctt taacggaacg attttggaga atcttctttt gggagccaag gaggggacga
     2161 cacaggaaga tatcttacgg gcggtcgaat tggcagagat tcgagaggat atcgagcgca
     2221 tgccactgaa ttatcagaca gaattgactt cggatggggc agggatttca ggtggtcaac
     2281 gtcagagaat cgctttggcg cgtgctctct tgacagatgc gccggtcttg attttggatg
     2341 aggcgactag cagtttggat attttgacag agaagcggat tgtcgataat ctcattgctt
     2401 tggacaagac cttgattttc attgctcacc gcttgactat tgctgagcgg acagagaagg
     2461 tggttgtctt ggatcagggc aagattgtcg aagaaggaaa gcatgctgat ttgcttgcac
     2521 agggaggctt ttacgcccat ttggtcaata gctagaaaga ggagaggatg aaaccagaat
     2581 ttttagaaag tgcggagttt tataatcgtc gttaccataa tttttccagt agtgtgattg
     2641 tacccatggc ccttttgctc gtgtttttac ttggctttgc aactgttgca gagaaggaga
     2701 tgagtttgtc cactagagct actgtcgaac ccagtcgtat ccttgcaaat atccagtcaa
     2761 ctagcaacaa tcgtattctt gtcaatcatt tggaagaaaa taagctggtt aagaaggggg
     2821 atcttttggt tcaataccaa gaaggggcag agggtgtcca agcggagtcc tatgccagtc
     2881 agttggacat gctaaaggat caaaaaaagc aattggagta tctgcaaaag agcctgcaag
     2941 aaggggagaa ccactttcca gaggaggata agtttggcta ccaagccacc tttcgcgact
     3001 acatcagtca agcaggcagt cttagggcta gtacatcgca acaaaatgag accatcgcgt
     3061 cccagaatgc agcagctagc caaacccaag ccgaaatcgg caacctcatc agtcaaacag
     3121 aggctaaaat tcgcgattac cagacagcta agtcagctat tgaaacaggt acttccttgg
     3181 ccggtcagaa tctagcctac tctctttacc agtcctacaa gtctcagggc gaggaaaatc
     3241 cccaaactaa ggttcaggca gttgcacagg ttgaagcaca gatttctcag ttagaatcta
     3301 gtcttgctac ttaccgtgtc cagtatgcag gttcaggtac ccagcaagcc tatgcgtcag
     3361 ggttaagcag tcaattggaa tcccttaaat cccaacactt ggcaaaggtt ggtcaggaat
     3421 tgacccttct agcccagaaa atcttggagg cagagtcagg taagaaggta cagggaaatc
     3481 ttttagacaa ggggaaaatt acggcaagtg aggatggggt gcttcatctt aatcctgaga
     3541 ccagtgattc tagcatggtt gcagaaggtg ccctactagc ccaactttat ccatctttgg
     3601 aaagagaagg gaaagccaaa ctcacagcct atctaagttc aaaagatgta gcaagaatca
     3661 aggtcggtga ttctgttcgc tatactacga ctcatgatgc cgggaatcaa ctttttctag
     3721 attctactat tacaagtatt gatgcgacag ctactaagac tgagaaaggg aatttcttta
     3781 aaatcgaggc ggagactaat ctaacttcgg agcaggctga aaaacttagg tacggggtgg
     3841 aaggccgtct acagatgatt acgggcaaga aaagttatct acgttattat ttggatcaat
     3901 ttttgaacaa agagtaatgt tcgtgttttt agagttaaat aatttttaaa ctgtgagaaa
     3961 gattcttctt gcagtttttt ctttacaatt tttgaaaaac atctgctatt tattcggtta
     4021 aattcttgtg ttttttggtt ttttgtggta aaatgtgctc aagtaatacg aaaggcgaac
     4081 tttaaaatgt caaaacaatt gatctattcg ggaaaagcta aagatatcta tacaactgag
     4141 gatgaaaatc ttattatttc aacttacaag gaccaggcga ctgctttcaa tggtgtcaag
     4201 aaggagcaga ttgcaggtaa gggagtcttg aataatcaga tttcatcttt tatttttgag
     4261 aaattaaatg cggctggtgt ggcgactcac tttgtggaga aactttcaga cacggaacaa
     4321 ctcaataaaa aggttaagat tattcctttg gaagtcgtgc tccgcaacta tactgctggt
     4381 tccttttcaa aacgttttgg tgtggatgag ggaatcgcct tggagactcc gattgtcgaa
     4441 ttttactaca aaaatgatga tttggatgat ccatttatca atgatgagca tgtaaaattc
     4501 ctacagattg cggatgacca gcagattgcc tacttgaagg aagaaacgcg tcgtatcaat
     4561 gaactattga aagtctggtt tgctgagatt gggcttaaat tgattgactt taagctagag
     4621 ttcggttttg acaaggatgg caagattatc ttggcagacg aattttcacc agataactgc
     4681 cgcttgtggg atgctgatgg caaccacatg gataaggatg ttttccgtag aggattggga
     4741 gaactaaccg acgtttatga gattgtttgg gaaaagttgc agggtttaaa ataacaacct
     4801 caaggctgtt tgggaatatt gcaagagctg aaataaagga ataagaattg atggataaac
     4861 gtatttttgt tgaaaaaaag gctgattttc aggtcaagtc agagagtttg gttagagagc
     4921 tccagcacaa cttgggactg tcaagcttga aaagtattcg tattgtgcaa gtatatgatg
     4981 tatttgactt ggttgaggac ttgtttgcac ctgcagagaa gcacattttc tctgagcagg
     5041 taaccgacca tgttttagat gaagtatctg tgcaggcgga tcttgctaac tatgctttct
     5101 ttgccattga aagtctacca gggcagtttg accagcgtgc agcttcgtca caggaagcct
     5161 tgcttttgtt gggaagttcg agtgacgtga cagtcaacac agcccaactt tacttggtga
     5221 ataaagatat tgatgcgact gagttggaag ctgtcaaaaa ctacctgctc aatccagttg
     5281 attctcgttt caaggatatc acgataggga ttgccaagca ggagttttca gagtcagaca
     5341 agaccattcc aaaattgcct ttctttgaaa gctatacagc agaagacttt gctcgctaca
     5401 aggccgaaca agggatggcc atggaagtgg atgatttgct ctttatccaa gactacttta
     5461 agtcaatcgg gcgcgtgcca actgagactg aactcaaggt tttggacact tactggtctg
     5521 accactgccg tcatacgact tttgagacag agttgaaaca catcgacttt tcagcttcta
     5581 aatttcaaaa gcaattgcag tcaacctatg acaagtatat tgccatgcgc gaggaattag
     5641 gtcggtctga aaaaccacaa accttgatgg atatggcgac tattttcggt cgttatgagc
     5701 gtgctaatgg acgattggat gatatggaag tctctgacga aatcaatgcc tgctcagttg
     5761 aaattgaagt ggacgttgat ggtgtcaagg aaccttggct cctcatgttt aaaaacgaaa
     5821 ctcacaacca tccaacagaa attgagccat ttggtggagc ggctacctgt atcggtggag
     5881 ctattcgtga tccgttgtca ggccgttcct atgtttacca agccatgcgt atttcaggtg
     5941 ctggtgatat tacagcaccg atttcggaaa ctcgtgctgg gaaattgcca caacaagtca
     6001 tttctaaaac agcaactcat ggttattctt catatggtaa ccagattggg cttgccacaa
     6061 cctacgttcg tgaatacttc cacccaggct ttgtagctaa acgtatggaa cttggtgccg
     6121 ttgttggtgc ggctcccaag ggcaatgttg tccgtgaaaa acctgaagca ggtgatgtga
     6181 tcatccttct cggaggtaaa acaggtcgtg atggtgtcgg tggtgcgacg ggctcttcta
     6241 aggttcaaac agttgagtct gtagagactg ctggtgctga ggttcaaaaa ggaaatgcca
     6301 tcgaagaacg caagattcag cgcctcttcc gtaatggcaa tgtcactcgt ctgatcaaga
     6361 agtccaatga ctttggggca ggcggtgtct gtgtggctat cggtgaattg gcagacggtc
     6421 ttgaaatcga cctcaacaag gtgcctctta aataccaggg cttgaatggt acagaaattg
     6481 ccatctctga atcacaagaa cggatggcgg tcgtggttcg tcctgaagat gtggatacct
     6541 tcgttgccga atgtaacaaa gaaaatattg atgctgttgt ggtggcgaca gtaactgaaa
     6601 aaccaaatct tgtcatgcac tggaatggtg agacaatcgt tgacttggag cgtcgtttcc
     6661 ttgacatcaa tggtgtgcgc gtggttgtcg atgccaaagt tgtggacaag gatgtcaaac
     6721 tcccagaaga gcgtcaaaca tctgctgaaa cactggaatc agataccctt acggttctat
     6781 ctgacctcaa ccatgcaagt caaaaaggat tacagactat ctttgactgc tctgttggac
     6841 gctcaacggt taatcaccca cttggtggtc gttaccaact cacaccaact gaggcatctg
     6901 tgcagaaatt gccagttcaa cacggtgtga ctcatactgc gtcggtcatt gctcaaggtt
     6961 tcaacccata tgtagctgaa tggtctccat accacggtgc tgcttatgcg gttatcgaag
     7021 caactgctcg tttggtggct gctggtgcca actggtccaa ggctcgtttc tcttaccaag
     7081 aatatttcga gcgtatggac aagcaagcag agcgttttgg tcagccagta gccgctcttc
     7141 taggctctat tgaagctcag attcaacttg gcttgccatc tatcggtggt aaggactcca
     7201 tgtctggtac ctttgaagaa ttgaccgttc cgccaacctt ggttgccttt ggggtgacga
     7261 cggcagatag ccgtaaggtg ctctctccag aatttaaagc tgttggggaa aatatctact
     7321 acatcccagg tcaagccctc tctgcagaga ttgattttga cttgattaag aaaaattttg
     7381 ctcagtttga agcaagccaa gctgaccata aagtgacatc tgcatcagct gtcaaatacg
     7441 gtggtgtagt tgaaagtttg gctcttgcta cctttggaaa ctatattggt gcagaggtga
     7501 ccttgcctga acttaaaaca gctttgacag ctcaattagg cggctttgtc ttcacatctc
     7561 ctgaagaaat tgctggagta gagaagattg gacaaacgaa agcagacttt acactgactg
     7621 tcaacggtgt gaagctagat ggacacaagc ttgacagtgc atttcaaggg acattggaag
     7681 aagtttaccc aacagaattt acccaagcga aagaactaga agaagtacca gctgtggcat
     7741 cagatgttgt gattaaagcc aaagaaaagg ttgaaaaacc tgtggtttac atcccagtct
     7801 ttccaggaac caactcagaa tatgattcag ctaaggcctt cgaaaaagaa ggtgcagagg
     7861 tcaatttggt gccattcgtg accttgaatg aagaagctat tgtcaagtca gttgaaacta
     7921 tggttgacaa tatcgacaag actaatattc tcttctttgc tggtggattc tcggctgcgg
     7981 atgaaccaga tggttcagct aagtttatcg tcaatatcct gcttaatgaa aaagtgcgtg
     8041 tggctattga tagctttatc gcccgtggtg gtttgattat cggtatttgt aatggattcc
     8101 aagccttagt caaatcgggt ctcctaccct acggaaactt tgaagatgct aacaatacta
     8161 gcccaaccct cttctacaat gatgccaacc aacacgtggc caagatggtg gaaactcgca
     8221 ttgccaatac caactcacca tggttggctg gtgtgcaagt gggcgatatc cacgctattc
     8281 ctgtttcgca cggtgaaggg aagtttgtcg tgacggctga ggaatttgca gagctccgtg
     8341 acaatggaca aattttcagc caatacgttg actttaacgg taaaccaagt atggattcta
     8401 agtacaatcc gaatggttct gtccatgcca tcgaaggaat taccagcaag aatggtcaaa
     8461 tcatcggtaa gatgggccac tcagaacgtt atgaggatgg tcttttccaa aatatcccag
     8521 gcaataaaga ccaacacctg ttcgcatcag cggttaaaca tttcactgga aaataagact
     8581 tacagatttt ctaatagata gtatcagtaa tgtaaaagtc atgtaaatct agctcttgat
     8641 gattacaaat gaaaattagg tataaaaaat gacatacgaa gtaaaatctc ttaatgaaga
     8701 atgtggtgtt ttcggtattt ggggacatcc agatgctgct aagttgacct attttggact
     8761 ccacagtctt caacaccgtg gtcaggaggg ggcaggaatc ctctccaatg atcaaggaca
     8821 actgaagcgc catcgtgaca tggggctttt atcagaagtt ttcagaaatc cagccaattt
     8881 ggataaattg acaggagctg gtgcgattgg gcatgtgcgt tatgcgactg ctggcgaagc
     8941 ttctgttgat aacatccagc ccttcctctt ccgttttcac gatatgcagt ttggcttggc
     9001 tcataatgga aatctgacca atgcagcctc tctcaagaaa gaactggaac aaagaggagc
     9061 aattttcagc gcgacttcgg actctgaaat cttggctcac ctcattcgtc gcagtcataa
     9121 tcctagcctg atgggcaaaa tcaaggaagc gctcagcctt gtcaaaggtg gttttgccta
     9181 tatcttgctg tttgaggaca agttgattgc ggctcttgac cctaatggct ttcgtccgct
     9241 ttctatcggg aaaatggcca acggagcggt ggttgtttcc tctgaaacct gtgcttttga
     9301 ggtcattggt gccgagtgga ttcgtgattt gaagccaggt gagattgtga tcattgatga
     9361 cgagggcatt cagtatgaca gctatacaga tgatactcag ttggcgattt gttctatgga
     9421 gtatatctac tttgctcgcc ctgattctaa tatccacggt gtcaatgtcc atacggcacg
     9481 taagagaatg ggagcgcaat tggcgcgaga atttaagcat gaggcagata ttgtagttgg
     9541 tgtgcccaat tcttccctaa gcgcggctat gggatttgcg gaagaatcag gcttaccaaa
     9601 tgaaatgggt ctgatcaaaa accaatacac ccagcgaact tttatccaac cgactcaaga
     9661 attgcgggag caaggagtgc ggatgaaact gtctgctgtt tcgggtgttg tcaaaggcaa
     9721 acgtgtggtc atggtggatg attccattgt acgtggaaca acctctcgtc gtatcgttca
     9781 gctcttgaaa gaagcgggtg cgactgaggt tcacgttgcc attggaagtc ctgcactagc
     9841 gtatccatgt ttctacggga ttgatatcca gacccgtcag gagctgattg cagccaatca
     9901 tacggtcgaa gaaactcgcc aaatcattgg tgcggacagt ctgacttatc tttcaattga
     9961 tggcttgatt gagtcgattg gtatcgaaac agatgcgccg aacggtggtc tctgtgtcgc
    10021 ttactttgac ggtgactacc caacgcctct ctatgactac gaagaagact atcgtagaag
    10081 tttggaagaa aagaccagtt tttacaagta ggcgacagat tctccattaa agaaaaggaa
    10141 aaaacaaatg acaaataaaa atgcatatgc ccagtcgggt gtggatgttg aagcgggtta
    10201 tgaagttgtt gaacggatta aaaagcacgt ggcccgtacg gagcgtgcag gtgtcatggg
    10261 agctcttggt ggctttggtg gtatgtttga cctttccaag actggggtta aagaacccgt
    10321 cttgatttca gggactgacg gtgtcggaac caagctcatg ttggctatca agtacgacaa
    10381 gcacgatacc atcgggcagg actgtgtggc catgtgtgtc aacgacatca ttgctgcagg
    10441 tgcggaaccc ctctattttc tcgactacgt agcgacaggg aagaatgaac cagctaagct
    10501 agaacaagtg gttgctggtg tggcagaagg ttgtgtgcag gctggtgctg ccctcatcgg
    10561 tggggaaacg gctgaaatgc cgggcatgta cggcgaagac gactatgact tggctggttt
    10621 tgcggtcggt gtggctgaaa aatctcaaat cattgacggt tcaaaggtgg tagagggaga
    10681 tgttcttctc ggacttgctt caagtgggat tcactcaaat ggttactctt tggttcgtcg
    10741 tgtctttgcg gattacacag gtgaggaagt cctaccagaa ttggaaggca agaaacttaa
    10801 ggaagttcta cttgagccga ctcgtatcta tgtcaaggct gtcttgccgc tcatcaaaga
    10861 agagttggtc aacggcattg cccacatcac aggtggtggc tttatcgaaa atgtccctcg
    10921 tatgtttgca gatgacctag ctgctgaaat tgatgaaagc aaagttccag tgcttccaat
    10981 tttcaaagcc cttgaaaaat atggtcagat taaacacgaa gaaatgtttg aaatcttcaa
    11041 tatgggtgtg ggacttatgt tggcggtcag ccctgaaaat gtagagcgtg taaaagaatt
    11101 gttggatgaa gcagtctatg aaattggtcg catcgtcaag aaagaaaacg aaagtgtcat
    11161 tatcaaatga aaaaaatagc ggtttttgcc tctggtaatg gctcaaattt tcaggtgatt
    11221 gccgaagaat ttccagtgga gtttgtcttt tcagaccatc gtgatgccta tgtgcttgag
    11281 cgtgcaaagc agctcggcgt tctgtcctat gcttttgaac tcaaggagtt tgagagcaag
    11341 acagactacg aagcagccct tgtcgaactc ttggaagaac accagattga cttggtttgc
    11401 ctagcaggct acatgaaaat cgttggacca accttattgt cggcttatga aggtcggatt
    11461 gtcaacattc atccagccta cttgccagaa tttccaggag ctcatgggat tgaggatgct
    11521 tggaatgctg gcgtgggtca gtctggtgtg accattcact gggtggattc gggtgtggat
    11581 acaggccagg tcatcaaaca ggttcgtgtg ccacgactag ctgatgatac cattgacaga
    11641 tttgaagctc gcatccatga agcagagtac aggttgtatc cggaagtagt gaaggctcta
    11701 tttacagatt gactttttga tgattcatat gatatctttg attttaaatt ggagtcagtg
    11761 tttgttgaag acggcttcaa acggaggtat ttgtaatgtt agaatctaaa aaaacaactc
    11821 gatatgtatt ttatgtctat ctgatgttat taacttgggg aatcttattt aagtttgaaa
    11881 caaatcctga atttatagca tttttcttag ctccaaggta tatcaattgg attccatttt
    11941 cagaaccact aatagtcgat ggaaaaattg tttttgctga aatgttattt aatctgattt
    12001 cctttattcc attaggtgtt tgtttccctt tgataaaaac taatttatct agtttaagaa
    12061 tagtcgggac aggtttcttg attagtttat tgtttgagtg cttacagtat attttagcaa
    12121 taggtataac agatataacg gatttgactt taaatacgct aggtgtctgt gtaggcttac
    12181 tgatttatca aatttttata agagtgttca aatcacagac tagaaaatgg atcaatatct
    12241 taggtatgct tagccttggt tttgcttatc ttgttttact gttactgcat ttaattggtg
    12301 tttaactaat gattaaaaag gagaatataa tgactaaacg cgtcttaatc agcgtctcag
    12361 acaaagcggg cattgttgaa tttgcccaag aactcaaaaa acttggttgg gagattatct
    12421 caacaggtgg aactaaggtt gcccttgata atgctggggt ggataccatt gctatcgatg
    12481 atgtgactgg tttcccagaa atgatggacg gtcgtgtgaa gaccctccac ccaaatatcc
    12541 acggagggct tctcgctcgt cgtgacttgg atagccactt ggaagcggct aaggacaaca
    12601 agattgagct cattgacctt gtggtggtca acctttaccc atttaaggaa actatcctta
    12661 aaccagatgt gacttatgct gatgcagttg aaaatatcga tattggtggg ccgtctatgc
    12721 ttcgttcagc agcgaaaaat catgccagtg ttacagttgt ggtagatcct gctgactacg
    12781 ctgtggtttt ggacgaattg gcagcaaacg gcgaaacctc ttatgaaact cgccaacgtt
    12841 tagcagccaa agtatttcgt cacacagcgg cttatgacgc cttgattgca gaatacttca
    12901 cagctcaagt gggtgaaagc aagcctgaaa aactcacttt gacttatgac ctcaagcaac
    12961 caatgcgtta cggtgagaat cctcaacaag acgcggactt ttaccagaaa gctttgccta
    13021 cagattactc tattgcttca gccaaacagc tcaacgggaa agaattgtca tttaataata
    13081 tccgtgatgc agatgctgct atccgtatca tccgtgactt caaagatagt ccaaccgttg
    13141 tggctctcaa acacatgaat ccatgtggaa ttggtcaagc tgatgacatc gagactgctt
    13201 gggactacgc ttatgagtct gacccagtat ctatctttgg tgggattgtc gtcctcaacc
    13261 gtgaggtgga tgctgcgaca gctgagaaga tgcacggcgt tttcctcgaa atcatcattg
    13321 caccaagcta tacggatgaa gcgctagcta ttttgatcaa taaaaagaaa aacttgcgta
    13381 tccttgcctt gccatttaat gctcaagagg ctagcgaagt ggaagcagaa tacacaggtg
    13441 tagtcggtgg acttctcgtg caaaatcaag acgtggtcaa ggaaagccca gctgactggc
    13501 aagtggtgac caaacgtcag ccaactgaga cagaagcgac tgctcttgag ttcgcttgga
    13561 aggctatcaa gtacgtcaaa tcaaatggta ttatcgtgac caacgaccac atgacacttg
    13621 gtgttggtcc aggtcaaacc aaccgtgtgg cttctgttcg ccttgccatt gaccaagcca
    13681 aagatcgtct gaacggggcg gtccttgctt cagatgcctt cttcccattt gcggataacg
    13741 tggaagaaat cgccaaagca ggaattaagg ccatcatcca gcccggtggc tctgtccgtg
    13801 accaagaatt catcgaagca gcggataaat acggcttgac tatggtcttt acaggtgtga
    13861 gacattttag acattaagaa gataaaaggg aagaaaacag tttctttcct tttttggctt
    13921 aaaatgctaa ctgaaacaag attaaaacga acttttttga tataatgttg gtaaataatt
    13981 cgcaaaagag gttgaggaat gaaactgctt gttgtcggtt ctggtggtcg tgagcatgcg
    14041 attgctaaaa agttacttga atcaaaagac gtggaaaaag tctttgtagc tcctgggaat
    14101 gacggtatga ctctggatgg tctggaattg gtaaatatat ctatttccga acattataaa
    14161 ttgattgact tcgcaaaggc caacgatatt gcttggacct ttatcggtcc agatgacgcc
    14221 cttgcggctg gtatcgtgga tgatttccat gcagctggtc tcaaagcctt tggtccgaca
    14281 agattggcag cggagctgga gtggtccaag gatttcgcca aggaaatcat ggtcaaatat
    14341 ggtgtttcga cagcagccta tggcacattt tcagatttcg aggaagcaaa ggcctatatc
    14401 gaaaagcatg gtgcgcctat cgtagtcaag gcggatggct tggcgcttgg gaagggtgtc
    14461 gtcgttgctg agacggttga gcaagcggtc gaagccgctc atgagatgct tttggacaat
    14521 aaatttggtg actcaggtgc gcgcgtggtt attgaggaat tccttgaagg agaggaattt
    14581 tcactctttg cctttgtcaa tggtgataag ttctacatca tgccaacggc tcaggaccac
    14641 aaacgtgcct acgatggcga caaagggcct aacacgggtg gtatgggtgc ctatgcgcca
    14701 gttccacact taccacagag tgtagttgat acagcggttg acaccattgt caagccagtt
    14761 ctagaaggga tgattaaaga aggtcgccct tatctgggag ttctttacgc agggcttatc
    14821 ctgacagctg atggaccgaa agtcattgag ttcaacgctc ggttcggaga tccagaaact
    14881 cagattatct tgcctcgctt gacctctgac tttgctcaaa atatcacaga tatcctggat
    14941 agcaaggagc caaatatcat gtggacggac aagggtgtga ctctgggtgt ggttgtcgca
    15001 tccaagggct acccgctaga ctatgaaagg ggcgttgagt tgccagccaa gacagaaggc
    15061 gatgtcatca cctactatgc aggggctaag tttgcggaaa atagcagagc actgctctca
    15121 aacggcggac gagtttatat gctcgttacc acagcagata ccgtcaaaga agcccaagcc
    15181 agcatctacc aagaactatc ccaacaaaaa atagaaggac tcttctaccg aacagatatc
    15241 ggaagcaagg caattaagta aagatataag aataacgcgc cgtagtcgcc aaacacgata
    15301 atggtcgtcg tggtgaaaag accagaacag tgaatgttct ggtcaggggg aaacttggag
    15361 accgtaggct caaagtttag gaatgaaacc gaaggtttgc ttccgcctcc atcacctaag
    15421 accattatca aaaagaaaaa taaaaattca caaaatacgt taatgatcgt atggtttgcg
    15481 agcgttagcg agctaatata gaacaatcac cgccgttgtg aaagaacgat tggatgataa
    15541 tccaatcgtt cagggaaatt ggaagacctt gggtttccaa tttaggcatg agacaccttt
    15601 ggtggctgct gccgtccctc acaagctaag gtgattgttg aaaaagagga aaaaggagaa
    15661 gaaatgaaac cagtaatttc catcatcatg ggctcaaaat ccgactgggc aaccatgcaa
    15721 aaaacagcag aagtcctaga ccgcttcggt gtagcctacg aaaagaaagt tgtttccgca
    15781 caccgtacac cagacctcat gttcaaacat gcagaagaag cccgtagtcg tggcatcaag
    15841 atcatcatcg caggtgctgg tggcgcagcg catttgccag gcatggtagc tgccaaaaca
    15901 acccttccag tcattggtgt gccagtcaag tctcgtgctc ttagtggagt ggattcactc
    15961 tattctatcg ttcagatgcc gggtggggtg cctgttgcga ccatggctat cggtgaagct
    16021 ggagcgacta acgcagctct ctttgccctc cgtctcctct ctgtagaaga taagtccatt
    16081 gcggatgcac ttgccaactt tgctgaagaa caaggaaaaa tcgcagagga gtcgtcaaat
    16141 gagctcatct aaaacaatcg gaattatcgg tggcggtcaa ctgggtcaga tgatggccat
    16201 ttctgctatc tacatgggcc acaaggttat cgcgctggat cctgcggcgg attgcccggc
    16261 ctctcgcgtg gcggaaatca ttgtggcacc ttataacgat gtggacgccc tccgtcagtt
    16321 ggcagaccgt tgcgatgtcc tcacttatga gtttgaaaat gtcgacgctg acggtttgga
    16381 tgccgttatc aaggatggac aactccctca aggaacagat ctgctccgca tttcgcaaaa
    16441 tcgtattttt gaaaaggact ttttgtcaaa caaggctcaa gtcactgtgg caccctacaa
    16501 ggtcgtgact tctagcctag acttggcaga tatcgacttg tcgaaaaact atgtcctcaa
    16561 gactgcgact ggtggctacg atggtcatgg acaaaaggtt attcgttcag aagcagactt
    16621 ggaagcagcc tatgcgctag cagactcagc agactgcgtc ttggaagaat ttgtcaactt
    16681 tgaccttgag atttctgtca tcgtgtcagg aaatggcaag gaggtgacgt ttttcccagt
    16741 tcaggaaaat atccaccgca acaatatcct gtctaagacc atcgtaccag cccgcatttc
    16801 tgaaagtcta gtagacaagg ctaaagctat ggcagtgcga atcgcagaac aactcaactt
    16861 gtctggaact ctctgtgtgg aaatgtttgc gactgatgat gacgttattg tcaatgaaat
    16921 cgccccacga ccacataact ctgggcacta ttctattgaa gcctgtgatt tctctcagtt
    16981 tgacacccat attctcggtg ttctcggagc accattacca gtcatcaaac tccatgcgcc
    17041 tgccgtcatg cttaacgttc tcggccagca tgttgaggcc gctgaaaaat atgtcacaga
    17101 aaattcaagc gcccacctcc acatgtatgg taaaatagaa gcgaagcaca accgcaagat
    17161 gggacatgtg actttgatta gtaatgaacc agatagtgtg ggagagtttt aggggagagg
    17221 ggtctaaaga aaaaatgttt gaaaaaatta aaggaattaa tataaaatca ggtatttttg
    17281 aagatgaaac aaaattagaa ctctttgaag gaaattttga gggaacaaat ccagtacaaa
    17341 acgatagggc aagtttattg tttggaagga atggttcagg gaaaagtacc attgctcgag
    17401 gaataaatca attaaaaaat ggtgagattg gaacagatag agtatcattt attgataaaa
    17461 ataataataa tattgtactt agtgatactg aacgaaaatc gatatttgtt ttcaatgaac
    17521 actatgttga tcagaaagtc aaaattgctc aagaagggtt agatacaatt gtaattttag
    17581 gtgaacaggt tgatatcgat gaggaactgg atagattaag aacgcagtta tcagaatcac
    17641 aaattgaatc tcaagattat tatgctgaat atgaagaata tttagatgaa aaaaatgaaa
    17701 aatctccaga tttttggaaa aaggaaatga cagattcttt gaaaggagta ggcaactggg
    17761 ccgaaagaga tagggagata aaaggaaatc gagctgcatc tcccgttcat aataatacct
    17821 ttcaaaattt tgttgattta caaccaatct tagataaaaa tgagttagag gttgaattca
    17881 acaataaaaa agctagatat ttttcaataa gagattccgc agttactata aataatgaac
    17941 tatctttacc tgatattaat tttgatagca atgaattatc aactttattg tctgaaaaaa
    18001 tcgaagaacc tgagttgaat tctagggata agtatttact gacattatta tctgattcca
    18061 caaaaggtga acgtcatttg agagaagtta aagatttctt tgaagatgaa catcaaaaaa
    18121 aatgtccttt ctgtactcaa tcagtatcag aagatgttaa agttgaactc acgaatggca
    18181 taactaaact actatcaaga gcagtcgaag aacaccaatc cgcattgaga ggtaaaaaaa
    18241 ttgatgagat taatcaagat ttttctggtt atgaacagat agatccaata ttaattcagt
    18301 cttatcaaaa tagtattaat gctttgaatg ctaaatttaa cgaaattaac tcaataatcg
    18361 ataagaa
//
LOCUS       DAVLAQ010000035        17537 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000035 DAVLAQ010000000
VERSION     DAVLAQ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.035"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(554..1690)
                     /locus_tag="VXB71_001339"
     CDS             complement(554..1690)
                     /locus_tag="VXB71_001339"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0451449.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNDFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(1752..2189)
                     /locus_tag="VXB71_001340"
     CDS             complement(1752..2189)
                     /locus_tag="VXB71_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0451450.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(2191..4146)
                     /locus_tag="VXB71_001341"
     CDS             complement(2191..4146)
                     /locus_tag="VXB71_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0451451.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEIMKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(4170..5939)
                     /locus_tag="VXB71_001342"
     CDS             complement(4170..5939)
                     /locus_tag="VXB71_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0451452.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            6148..7488
                     /locus_tag="VXB71_001343"
                     /pseudo
     CDS             6148..7488
                     /locus_tag="VXB71_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(7616..8638)
                     /gene="cbpF"
                     /locus_tag="VXB71_001344"
     CDS             complement(7616..8638)
                     /gene="cbpF"
                     /locus_tag="VXB71_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV0451453.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(8657..9478)
                     /gene="cbpG"
                     /locus_tag="VXB71_001345"
     CDS             complement(8657..9478)
                     /gene="cbpG"
                     /locus_tag="VXB71_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0451454.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHSYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(9559..9798)
                     /locus_tag="VXB71_001346"
     CDS             complement(9559..9798)
                     /locus_tag="VXB71_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451455.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(9948..10214)
                     /locus_tag="VXB71_001347"
                     /pseudo
     CDS             complement(9948..10214)
                     /locus_tag="VXB71_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(10239..10550)
                     /locus_tag="VXB71_001348"
     CDS             complement(10239..10550)
                     /locus_tag="VXB71_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0451456.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(10475..10706)
                     /locus_tag="VXB71_001349"
                     /pseudo
     CDS             complement(10475..10706)
                     /locus_tag="VXB71_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(10707..11339)
                     /locus_tag="VXB71_001350"
     CDS             complement(10707..11339)
                     /locus_tag="VXB71_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0451457.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(11353..12348)
                     /locus_tag="VXB71_001351"
     CDS             complement(11353..12348)
                     /locus_tag="VXB71_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0451458.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(12345..13043)
                     /locus_tag="VXB71_001352"
     CDS             complement(12345..13043)
                     /locus_tag="VXB71_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0451459.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(13120..14130)
                     /locus_tag="VXB71_001353"
     CDS             complement(13120..14130)
                     /locus_tag="VXB71_001353"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0451460.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(14114..15121)
                     /locus_tag="VXB71_001354"
     CDS             complement(14114..15121)
                     /locus_tag="VXB71_001354"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0451461.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDILIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSFEEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(15108..16061)
                     /gene="mvaD"
                     /locus_tag="VXB71_001355"
     CDS             complement(15108..16061)
                     /gene="mvaD"
                     /locus_tag="VXB71_001355"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0451462.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(16043..16921)
                     /gene="mvk"
                     /locus_tag="VXB71_001356"
     CDS             complement(16043..16921)
                     /gene="mvk"
                     /locus_tag="VXB71_001356"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0451463.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITETCVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(17043..17222)
                     /locus_tag="VXB71_001357"
     CDS             complement(17043..17222)
                     /locus_tag="VXB71_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0451464.1"
                     /translation="MLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNT
                     TVDGYFVNYNGEWVQ"
BASE COUNT         5397 a         3841 c         3068 g         5231 t
ORIGIN      
        1 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt gtttcatttt actatataga
       61 tcacattcga aagaattcgt tccaaaattg cttggttcgt tcttctcttg gacgactaaa
      121 gaattgatgg gcattatttt tttcaacaat tttcccactg tccataaaaa taacatgatg
      181 ggctacatct ctagcaaaac ctatctcata aagctgatca aaaactcaat ctgaggagaa
      241 aatccaataa gactttccat aataaaggac atcctatcaa gatttttgaa cacccgatag
      301 gctgcctttt tccgattttg aagacttttt gtccagcttc ttttacctta taaataacaa
      361 caaaaatcaa agacaagcta gaaagattac cgcagataac tcaaacagtg ttttgaggtt
      421 gcagataaga ctgacggagt cagctcaaag cactgctttg aggttgtaga tagaactgac
      481 gaagtcagct caaaatactg ttttgaggtt gcagatggat gctaacctga tttgaagaga
      541 ttttcgaaaa agattaaata tactctacaa tttgctcaat caattcttgg tcgtctaaac
      601 ctgtaacttg tataacaaca tctttgactg attgtttagc caacaattca cctaatcgaa
      661 tactttcttc atcatttaca tcgcgatagt caaaggcata gccaactgtt ttaagtaggt
      721 ttttatatga caaactgagt tctttcaatt cacgtatcgg ccggatgaat cgttcattat
      781 agcctaattt tcggattgga gtacgagcta cgcgactaac ctcgtccact atgaaagggt
      841 tttcgaatcg ttctataatg actttgtgat aattctccaa ttctttttta tcaaagttcc
      901 atttggcaat caagagactc cgaatttcag ctaatacaga ttcaatccga gatttgatat
      961 taggattttg aagagcttcc aaaattgtct tggcaccata atgcgcacca atgtaagctg
     1021 aagttgcatg tccagaattg actgaaaaaa gttttcgctc aataaagggt tctaaatctt
     1081 cttcataatg cacatcttct agacgtaaat ctggattttt aagacgcttg gtttccacga
     1141 cccattcatt aaagggctcg accataacaa aaagggaatc ttcgtgactt tgtgttggaa
     1201 caatcctgtc tactgcagca tttggaaaac ctatgtagtt atcagcaaat gtcaaacctt
     1261 ccggacttaa atatttcttg acttcttgat aaagaaattg agacccgcca atcatatttt
     1321 cacaggccat aacatccaat gcctgtgtat ttcctgcaac tcggcgagct tcgattcctt
     1381 tggctagaag ttcagcgata aaagggagta tattaggtcc gattgcagta gtaataatat
     1441 ccgtcttttg aatcgcttca atgacttgct caggatgttc tttgctatta attccagcca
     1501 cattagttac ttctatacga gactgtcctt tctgtgcaat ttcaatttca tacttgccct
     1561 tttcatttag agcatgaatt atctgattat tgacatccac aaaatcaata tggaaatcat
     1621 ttttaaatag aatttcacct ataaaaccac gaccgatatt accggcacca aaatgaacag
     1681 aatgtttcat tcaatttctc cttttcctat ttgagggaca tatatactag atgacaaatg
     1741 acgaaattca attattcaac agcatcaaat aagcgcaata cttcctcttt tgactgagca
     1801 tctgctagtt taagaacatt atctacatct gcacagaaga tagaaatttt ctgaataatt
     1861 tctaagtgtt cattaccaat accagcaata ccaaaaagaa ccgttgccac ttgagggtta
     1921 gatacattcc caaaatcaac ccctctaggg acttgaacga ctgtaatacc agacttgagg
     1981 acatcatttt ttgctgcatc tgttccatgc ggtatggcga taaagttacc catgtaaaca
     2041 gatagctctt tatctcgctc aatcatggct tcaatatagt cttcattaac atatccaccc
     2101 tcataaagaa cttgcccaca ataacaaata gcttcctcct tgttagaaaa ttgtttatta
     2161 agcttaatca aatgtttttc aagtttcata ttagttctcc aatttcttaa ttttttcgtt
     2221 aaaaatagta tttagcatct gataaataat ggattgattt cccgtcttgt aaatctctgt
     2281 ataaagatga ttttcaataa tcgactgact gatagctgtc attaaatctc tcgcttcctc
     2341 gctagcttct ttagacatta gcattagcag acaccttttg acctcttctt cctctcgttt
     2401 cattgacaat gcggagatag gtagtttgag ttcaaacata gtaaaactat ttgttgttac
     2461 tttgctagac tgactatgta aaagcaccag accagtatta ggaatagcca taggactatt
     2521 ctggaagtga gataacaatt ttcttgttag gtaatctctg tcactcacat tcttctgata
     2581 ttggatgatt tgttctaccg tgtgctcaaa tgattgatta ttctccaatt gaaccaactc
     2641 gaattgactc aaaagctgac tactagatat taaataatct tgcaagtcat aacttttctc
     2701 tggagcgata gcatcacgcg cgacaattgt acgatgtgcc tgtacatact gaagtcgttc
     2761 ctgtaattca agcaattctt tgacggttgg aaaactagaa attacatcga tttcctgatt
     2821 agtcagcggc ttggtagata aaatataatc atactgactg agatcaatac tgtggtaatc
     2881 tactagagac tgaatatcta tcaactctac aaaaggagca acactcttaa ttttactgac
     2941 taataaatct ctagtgaccc gacgttcatc cgttaaaagc aaaacacgga ctggataaat
     3001 ctctggacta cggcctaagc tagagataaa atgtagggca atcatgccat actcatactc
     3061 tgtatgaaga tatttcggaa aaatatcatt cactaaaaga ctgatgactg tataaagaaa
     3121 tttattcctt tcaactaaaa tctggacaga ttctggcaaa ttttcaccct gaaaaaggat
     3181 agggacgcct aaactgagcc gaatatgatg gaaaagaaaa ttgaataaaa ccttgtcctt
     3241 aaaaaagtca atcttggtat acatggaaac cgtatcaatc agatttgaaa tattgtagaa
     3301 aaattcacca tcaaatttct ccgtaaagag cggattgtcc tgacgtttaa tgattaattc
     3361 atccaagatg ctcgcaaaat agataatttc ctgaatacta taaaattgtg cagtctgctt
     3421 agagtaagtt tgaaaaattt tttgagaaat ttccaaagcc tgcttactag tattaggtga
     3481 attttcaatg ttttgctcct gacctataag agataacaag atcgcaaaaa acatcttcat
     3541 cctagcatcc atatctggaa aacctgacag ttgcttatta acaatctgac tggccagcct
     3601 agttctatct gcttctaaaa tatcaaagct cccaaaatta ccggttgaaa aatctgctac
     3661 tgagatacag tttgtcagta aaatagccaa aaatcttctc ttaccaactg aatcaccaga
     3721 aatccgataa cctttttgtc gttcaatttt cagatcaaag tctaaaagac gcttatcaat
     3781 atctgaaata tcctgaataa tagttacatt actgactttc gtgcactctt gcaatgcttc
     3841 attggtgaca aaaccgctct cagtcagaag gcgataggta atcaactctt gtctttcttg
     3901 gggactatac tcaactaaca cttcaagttc tgtcggcaaa tcatccaact ctccagtcaa
     3961 aatatagtat ttcccatgct tcattatttc gattccatat tgctccatgc tatctgtcaa
     4021 atctgataaa gttcgataaa ttgttctaga tgaaacctgt aagatttcag tcatatcttg
     4081 cattgaaagc ttccctacat gtaggaaagc cttcaataat tgttcttctc gtttggttaa
     4141 tagcattcgt aatttagaaa cctctagttc tatttgtaca ttctagcagc cattttgtca
     4201 tattctggtg ttgttactaa actatccaca ataagaaatt gagaattcgg tgctgcttgc
     4261 tgcacttctg cctgtaaaga aatagttgtt acaatcatta tgtttttaga attaaattca
     4321 cctaattctg aaattttggc agtagaaact ggaatacgaa tattcttgtt tctaaagata
     4381 gcccgaatcg tttcacagcc catagttgca gttccctgtg ctttaccata agcaactact
     4441 acagcatcaa tatggttaag gtcaatttcc tgactatcta ctggtgctga agttggtata
     4501 tctccttcaa tttctgctat tggagaagct cctgttaatg aagctacaat ttcatcataa
     4561 cgaggggacg ctaagaaatt atcaacagaa acatgaatag cacttggact cttgtcttta
     4621 gctcttggtg tcagttcttc ctgagtaaca attaatgttt ttggtgtatc aagcaaattt
     4681 gagattgcct gattagatac tggaatctct agacctgctt ttttaacctt atctcgaaga
     4741 atactagctc ccatagcaga gcttcccata ccagcatcgc aggcgaaaat gattttttcc
     4801 actgagtctg tcgaaacaac tgcatcaaca gaagttgata ctaactgacc tttagactga
     4861 gccttagctg cttgggtagc cgcctgagca gcttcgagcg aatcctcagt tgacttgtct
     4921 gcatgaagaa taagggctgc tacaaggaaa gaaacaactg ctgctactaa aacacctaga
     4981 agaacattta gatggggcca aacacctttt ggcgccgtag ccataatcgc aataatagaa
     5041 cctggtgaag ctggagattt aagaccagcg tctaagagtt gaaaagtaaa agttccagag
     5101 atacctcctg ccatagcagc taaaaataga gtaggcttca tcataacata aggaaagtaa
     5161 atttcatgaa tccctccgaa gaaatgaata accattgccc cccaagaaga agatttagca
     5221 gaacctttac cgaatacagc ataagctaat agaattccca ggcctggtcc aggattagct
     5281 tccaatagga agagaattga cttaccagct tgagctacct gttctactcc cagaggagta
     5341 aaaatgccat gattgagggc attattgagg aaaaggactt tagccggttc gatgataata
     5401 ttagccatag gaaggaggcg agcattgaca atagcctcaa caccattccc aacagctcca
     5461 gtaagagtcg atacgactgg accgattgcg tagaaagcca aaagcaataa tgcaaaacca
     5521 acgagaccag ctgagaagtt attaactaac atttcaaatc cgggacgaat tttttcttgg
     5581 aacttctcat caaatttctt gatagtccat cctcccagtg ggcccattac catagctccg
     5641 ataaacatag gaacactaga acctgtgatt gcaccaacag tagcaatagc tcctacaacg
     5701 gcaccacgtt ggccatggat catatatcca cctgtgtaac caatcaggat tggcaataaa
     5761 tacgttaaca taggaccaac aacagtagct aactgttcat ttggcagata gccatcagcg
     5821 ataaagaggg cagtcaatac tccccaagca ataaatgctc caatattggg cataaccata
     5881 tttgaaagcg atgtccctag tttttgaacc ctgactttca atgatacttt ttcttccatt
     5941 agatcatcct ccttttctta aaactagtat atacaaagtt aaaaaccttt aaaactaaag
     6001 ttttgtcaca gattttgtgt caaaacatta cttttgacga ggctgggcaa aaaggcttaa
     6061 aaattataaa acgcatcata tcaggtgtac atgaactaca ccccaaaagt tagacagaaa
     6121 aaatctaact tttggggtgt ttttattatg aaactaactt atgatgataa agttcagatc
     6181 tatgaactta gaaaacaagg atatagctta gagaagcttt caaataaatt tgggataagc
     6241 aattctaata ttaggtacat gattaaattg attgatcgtt acggaataga gttcgtcaaa
     6301 aaaggaaaaa atcgttacta ttctcctgat ttaaaacaag aaatgagtaa taaagtctga
     6361 catgaaggct ggactaaaga tagagtttct cttgaatacg gtctcccaag tcgtacgata
     6421 cttcttaact ggctagcaca atacaggaaa aacgggtata ctattgttga gaaaacaaga
     6481 gggagagtac ctaaaatggg acgtaagcca aaaacgagac ctgaagagag gacagaatta
     6541 gaacgtcttc aagcagaaaa tgagtacctg agagcggaga atgccatcct aaaaaagtta
     6601 agagaactcc gattgaagga ggagaaagaa gaaagacaga aattgttcaa gaattaatga
     6661 ctgaattttc gttagctctt cttctaaaag tcattaaact agctcgttcg acctactact
     6721 atcacttgaa acagctagat aaaccagata aggactaaga gcttaaagct gaaattcaat
     6781 ccatttttat cgaacacaag ggaaattata cttatcgccg ggttcattta gaactaagaa
     6841 atcgtggtta tctggtaaat cataaaagaa ttcaaggctt gatgaaagta ctcaatttac
     6901 aagctaaaac gcgacagaaa cgaaaatatt cttctcataa aagacgttgg caagaaggca
     6961 gagaatctca ttcaacgcca atttgaaggc tctaaaacaa tggaaaagtg ctacacagat
     7021 gtgacagaat ttgccattcc agcaagtact caaaagcttt acttatcacc agttttagat
     7081 ggctttaata gcgaaattat cgcctataat ctttcaactt cacccaactt agaacaagta
     7141 caaacaatgt tggaacaggc attcacagag aagcactaca agaatacgat tctccatagt
     7201 gaccaaggct ggcaatacca acacgattct tatcatcggt tcctagagag taagggaatt
     7261 caagcatcca tgtcacgtaa gggaaacagc ccagacaata gtatgatgga gtccttcttt
     7321 gggattctga aatcggaaat gttttacggt tatgagaagt cgtttcagtc gcttaagcaa
     7381 ttggaacaag ccattataga ctatattgat tactacaaca ataaacgaat taaggtaaaa
     7441 ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat taattgtcta
     7501 actgtttgag ggcagtacag aaaaaccttg atactatgcg ttttttgatt gtgaagactt
     7561 ttatccacct attatacaaa gttaagtatc catcacagtt tacaattagc cttcattact
     7621 taacccattc accattatag tttaagtagt aaccacctac tgtggtatta acagctaaag
     7681 cacctgaatc ataggcatag taccagttac cattgacttg gaaccagcct gttttcatat
     7741 ctccattact tgcatttaga tagtaccaag tcgaaccttc ctgataccaa ccagttgcca
     7801 tagctcctga tgaacggaga tagtaccatt tgttcccaag gttttgccaa ccagttttca
     7861 tatcgccatt ttcagcatct aaatagtacc aagttgaacc atcttgatac cagccagttg
     7921 ccatagctcc tgatgaacgg agatagtacc atttattacc aagatgttgc caacctgttt
     7981 gcatgatgcc agttgctgga tctagatagt accatggagc tgcttttagc ttctcttcat
     8041 cataggtaag agggtaatcc ttaacccaac cacgtgctag ctctccaacc gtcaatctgt
     8101 tgatgcgaga atcaaagcca ccatccttct gcaaataata ccagtcccca tcatcataaa
     8161 cccaaccagt ttttaaagta tgataactac gctgatcttc aaaataatag actcgtttct
     8221 ctgctgggct atcatattct tccccatgat gtttgttggt atttgtagca gtttttgctt
     8281 ctaacacttg cttgccaaca aattcttgta gtaccccatc ttgaccaaag taaaaccaat
     8341 ctggtctaaa agcaatctct tgtcttggag aaggaccaat cgtaaccccc ttgtgtggag
     8401 caggtatata ttgccagccg acaaccatct ctccggataa aggatcaaaa taatagtatt
     8461 tcccatctat cactctccag taggtttctt ttagatcccc ctttttgtag taggttctac
     8521 cattttcttg gacaaactgc catccttcag aatcatctgc aaatactgta ctggtcccta
     8581 gcaaaccgaa gaaaaatgtg gctagtgcga cttgcatcat ttttttcaaa agcttcattt
     8641 tatatatcct ccaacattaa atccactcac cagatgaagc gaagttataa actttaccat
     8701 cgatagtttg gctacctgta accattgctc catttgaatt gagataatac cattttccat
     8761 ttactttttg ccaatctgta agcatcttac cggaactgtc taaataatac caagtatcat
     8821 ttatctcctg ccaacccgtt tgtttatcat gttgtctata atggtaccaa ctaccattta
     8881 ttttcttcca tccttcaaga gagtaacctt taagaaccga ataaataaat ggcaaatttc
     8941 gttcatttaa tttaactgca ctgttaattt gattagctcc atctcctaaa gtatgcactc
     9001 ctactacacg gtgactagca tcataaactg tagatccact agacccctct aaagtatcaa
     9061 cttggtaatc caagaacatg ccatcatcac ttaaaacttg ttttttatct gtatacattt
     9121 gatgaacttt aaaattatat gatggatagc ctgtgatagt cacagttatt cctgtcaaat
     9181 ttttttgact agtaggaaga cccaaagtcc ctaattttgc accaatgggc tcttctagaa
     9241 ttaataaagc caagtcatat tcccttgcat ccttagaatt taaatttcta aattccttca
     9301 aataacgaac ttcctttact ttgatctttc caaatggttc ttgacttgga ctaacagccg
     9361 gaagaacata aatatcatcc gcttctttcc catagtcatg tctgtagtag ctgtgagccg
     9421 ctgtaattaa cacattatct ttaataaaat tcgcacttcc cctcccttct acattcattc
     9481 catcggctac tccataatac ttagataaaa ccatagctga agtcgaatac ggatactgta
     9541 aagtattatc aattttaatc aaatcatcat taccgataat acttctgatt gcttttggta
     9601 gtatgaacca tatgttggtg aaatctcaga taatgaagaa tcattagatc ctggaccttt
     9661 ttctagtgtc tcacttacct catattcttc acccgtacta gaaataacac tcaaagcaga
     9721 tactgtcgat aactggctag ccaataaagt actcgcaata attgaaatac ccaatttttt
     9781 ataaacagtt ttcttcatta ttgtatcctc ctaatgtaat tatagcgtac tattctaaat
     9841 ttcttaatct actatagaat caagaaatct accaccttct ttaaataccc tccattatca
     9901 cataaacagg taaacttttc aattaatgac tgcgcttttc aatcacgcta gaggtactta
     9961 cttgcttctt tgatactaag ttcagccatt ctttccttgt ttttctcaat aaagcatgtt
    10021 acccaagtgg gattcgtttt ggagtagtct cgcagagtcc agccaatggc tttattgata
    10081 aaaaattctg tttggttcaa gttatgaagg agaatctttt ccattaattg agtattggtc
    10141 ttctcttttc ttaacaactg gttgtcaata gcgacacgtc tcagccagat attatctgat
    10201 aggctccatt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcagattg
    10261 ctcaaaacac tgttttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag
    10321 aatattaaga ttatttcttc tagttcagga tgtttataca ccaaactccc tactactcga
    10381 tctaggatat ctaccgtgtc ccaccaggat tttgtcacga ctaactgctc tagcttaggc
    10441 aaatcggttt cctttagata agactgcatt gctttcaaat agttagcagc cacatattgg
    10501 tattttctag gctccttttc ccagcaagtg tctgcaaaat cccaatcgat aatctttgtt
    10561 tttttcgctt ctggaaaata tttttataga gtttatttct ttcaacctag aaaagaaaat
    10621 tgatggcaca tataggcttc catgggcctt gcttttttag agtcttttgc tgcttctagc
    10681 tcctcaagta aatctgctaa actcatctaa aactcctcat gccccaccaa atggtgctga
    10741 aaggcataga cagccgcctg ggtacgatcg ctaacttcaa gtttggcaag aatgttggac
    10801 acgtgggtct tgaccgtctt gagagagata aagaggtcat ctgcgatgcg ctgattttcg
    10861 tagcccttgg cgatgagttg gagaacatct cgctcacgcg cagtcaattc ttcatgaagt
    10921 tccatatgat tgcggtggta ttcaaccttc ttgctaacct cttgctcaat ggccagctcg
    10981 ccagcagcta ccttactgac ggcatgaagc aattcatctg cactagaagt cttgagcata
    11041 tagcctttgg caccagcatc taagactggc atgatttttt cattgtccaa ataagaggtc
    11101 acaatcaaaa tcttggcttc aggccattct ttaaggattg ctaaggtcgc gtcaatccca
    11161 ttcatctcag gcatgacaat atccatgaca atgacatctg gacgcagttc caaggccaag
    11221 tcaatccctt gagacccgtt ggacgcctca cccacaactt ctacatcgtc ttggaggtca
    11281 aagtagcttt tcaagcccaa tcggaccatt tcatggtcat ctactagtaa aattttcatc
    11341 tttactcctt tatcattcct tatctaacag gggaatacgg atatcaaccg ccagcccttg
    11401 cttgggagct gtcaagagtt gaactgttcc agccatatct tcaacccgct ccttgatatt
    11461 tcgcagtcca taactcaagt cgtctaagct ccctaactgg aaaccaatcc cattgtccac
    11521 caccttcagt tgcaattcaa catctgtctg atagaggtag acatctaggc aagatgcctg
    11581 ggcatggcgg agggtattgc taatcaactc ttgcaggata cggaagatat gctcctcgat
    11641 tttcttaggc aatttcgtca tattctgctt gagactaacc ctaagatcac tcttgtcctc
    11701 aagctctttt aagagaatct gaatcccttc tatcaagctc ttctgctcca gttcaactgg
    11761 tcgcaaatgc aagagcaaaa cccgcaaatc cttctgggct gtttctaaaa tagctgtgac
    11821 actctgcaac tggatctgca tcttttctct atccaatttc aaagcctgct gactgatacc
    11881 cgataaaatc atgtgggccg caaacaactc ctgactgact gtatcgtgca aatcccgagc
    11941 aattcgcttc cgttccttct cgatgatttc ctcttcctga gcaaggctct gattttcagc
    12001 tttttgaaga gcttctgtca aaaggttaag tttacctgat aaggacttga aactggcatc
    12061 caaatctgga tctgcaacct gaaccacttc ttgccctgcc aataaacgct tgagattagc
    12121 ctgcattttt cttagagaaa gctcttcgat ccctcgccaa aacagggcta agagacaggt
    12181 tatggacatg ctgaaaacca acaataaaaa gacaaatttt tctgtttttt cgacatcgtg
    12241 caaaaagata gaccagtcaa aatcaagtat ttccagcaag ctgtgggaga aaaaaaagac
    12301 aaacaggaag gaggtgagag caataatgac ataggcttgt tttttcatcc tctaaccacc
    12361 tccacatcac caatcatagt ggtcaagaaa atcttgacac tcttgttact cttgagatag
    12421 tcttttgttt cttgatgata gtgttcattg cggagggctc gcttgggctg gttgaaaaaa
    12481 gtcaaatccc catagagaca gttaacgctg agactgactt ccacatctac aggtacgatg
    12541 attttggtcg ttcctaccat ctttctgagg ataatgacat tgtcatgatt ggttaagatg
    12601 accctctcca gatgaatagt gtccttgccc atgaagcgaa agagattgat atcatcgaat
    12661 tggcaagtct ggtagcttga aaaatgatga agatttccaa accaacgatt tttctccttc
    12721 ttaaccgtca cgacctcttc aaaaaccaaa ttggtctgct ctttttcctg gttcatcatc
    12781 gggtaaagaa gaaagaggct atagataacc gcaacaaaaa tagctagaat cacaaaagga
    12841 ttgagcataa cgatgaaaaa gaagagaatg gttgccgcta ctaaaagaag attatttccc
    12901 tctttaccag tgtagtagcg aatcaaaagc aaaaagagga atagtatcag cagaaaacgc
    12961 gaaaaatgct ctgataccat caaaatcaga gctcctgtca gaagacaggc ttcgataaat
    13021 aaaaagattt taaattttct cataggttca tcctctccct tctattttat cacaattcaa
    13081 aaaagtcacc tcagtctgag gatggaaaaa aggcgctggt tacgcctttt tcatctgatc
    13141 ctttgcttct tttaattttc cataaagaag atagtctact ttttgtagat ctgctatggt
    13201 ggcacagtta agggaacaca taatcaagcg taggtctgct ttccagcctt ggacaatgcc
    13261 aatcacttct tcaactgtgt aggtttcaac caattccaga acggttcgtg acaatcccac
    13321 agacttagca ccaaaaacca agcacttaat catatccagc ggattccgaa cccctccact
    13381 aaccaagagt tcgaccttat ctttccattc ttgggcattg agaagggcct gcatggtaga
    13441 ctgaccccat tgattgaggt aatcacgctg gccactacga cggttttcga tataggcaaa
    13501 gctggtgcca ccacgacccg ataggtccac tgtacgaaca ccgaattcat aggctctttc
    13561 gattgtcttg gcatccattc caaagcccac ttccttgagg acaataggaa cgggaatttg
    13621 ctcgctataa tctgctagat gcgattgcca gcttctaaac ttcctttctc cctcgggcat
    13681 gagtaattcc tgcatgacat tgacatgcac ttgcaataga acaggattca tctcttctac
    13741 agtctgaagt cctaactcga caggcttgtc caatccaata ttggttccaa ggaggagatt
    13801 gggatgacta gacttgacag aaaaagaatc atccgttgga tttttgaggg ctgcgctata
    13861 agaacccgtt acaaataaaa taccacagga ttccgccacc tgagccagct tttgattgat
    13921 ttctcttccc ttattacttc caccagtcat ggcattgata taaaaaggaa agtcccactt
    13981 tcgaccagca aactctgtcg aaagatcgat ttcatccaga ttgtaaagag gcaaggaaga
    14041 atgaatcagc tccacctcat caaagctatt ataggaactt ttctgctcaa gggcatagag
    14101 gatatgctcg tccttacgat ttgtcgtcat gtcctatcct ttcttgatat aagagctcaa
    14161 tccccagatc ggcccaacga ttttttaagg ttttggttga ttgcgcatca aaactcaggg
    14221 cgatgccaca gtcaccacca ccagcaccac tactcttggc aacggcctgc aaatcttgac
    14281 tggcttcttt caactgtcta agcaaaggcg tgtaaatatc tgtactcaag ccttctaaaa
    14341 gcttgctggc tacttctact tgctcgataa tcttttctga tttcccctgt tccaaggctt
    14401 cctcaaaaga aaccaccgtt tcttttgagg aagttaaaaa attttgattg atattttgct
    14461 tgatttgctg gaccatgtga ctcgatacag ccacttcctt ggtccatccc actaagaaat
    14521 cacattctaa agttggtttc acttgtgaaa ttgaaaagcc ccaatcacgc tccagaactg
    14581 tcgccaagtt ttcttcttct aaccaagcag ccaccttctg gcgatcaaat gactggtaga
    14641 gaaccaaatc ctctgccaca atacaggcaa ggtcgcccat ggaaccattg tctcctcgct
    14701 tgagcaagac agcgctagtc agcttgaaca agagctcctg atcaacagaa acatcataca
    14761 gagccagtaa agccttgaca accaagacaa cgacgctgcc actagaacct agaccaaact
    14821 ttttcccttc tcgttccatt ttgccacaga tttctagaga aaaaggtctt aaattctgac
    14881 cacgaacagc gaggaagtct cccatcaaag caatcgtttc ttgaatcaag ctgtagtcag
    14941 gattaggcct taagtccact gcgaaatcaa acatatctga atagatacgg tagctgtcag
    15001 aaaaagcaat ctcagccctc atatagatga gaatatcctt tatcaaagct aactgccctg
    15061 gctctaaaat agcatattca cctgcccaat agagttttcc gcaagtttta acagcaatca
    15121 tcttgactca aatcctttgt ttttgacaca atcaagcgat aacgctgacc gaaaatttct
    15181 gacaaatact ccaagtcttt ctcctgacag aagaccttaa cattgggacc agcatccatg
    15241 gtaaagtagc aggcctctcc tttctcacga agctggcgaa caaagtccat agcctcataa
    15301 gaggcatccg tcagataaga aaaggctgga ctagcagtct ttgtcgtagc atgcatagcc
    15361 agggcatttt tctccgttaa ttctccaatc ttggcaaaat cattttcctt gagataaatc
    15421 agcatatcct gatagtcctt ctcagactga cgaacccagt cgtcgaaagt cgtcgaggtt
    15481 tccacacaaa gtttcatccc gtcacggcta gagattggtt ttttcttgtc ctctagcacc
    15541 aacataatca tagctagttt caagtctgtc tctacagggt aaatttctcc actatcctta
    15601 tcccaggctc ctagtggtcc ataaaaactc cgagaagaag agcctgaggc aaatttggct
    15661 tcctgtgcca actgacttct atccaatcca agcttgaaat aagcattaca agccttgacc
    15721 agggcggaca aaccactaga acttgaggac aggcccgctg ccgtaggcat attgttttga
    15781 gtatcgatac ggacaaagcc ctcaccagct ggacgataac ggtcaataat cttactcatc
    15841 ttggcatgct cgacctcatt ttgtagctga ccattgatgt aaaattcgtc agctgttaca
    15901 ttggctggta aaggcgacaa ggtcgtctct gtatacatat tttccaaagt tagagaaata
    15961 ctgctagtag caggcaccat ctctttttct tttttctttc cccaatattt gataatagca
    16021 atatttgcgt aggaacgtac tgttacaggc tctctatcca tgtctgaaca gctcctttct
    16081 cttctaatct ttctgctagt tcttgtgcgt gtgtcaaatt ggttaccaag gctatgatac
    16141 aacctcctag cccaccaccg ctcatcttgg cacccagagc accatggcta agagtcgttt
    16201 caaccaaaaa gtctgcctca gggctactga ctccaatttc ttttaaatgt aaatgcgctt
    16261 gactgaggat ttgtcccagt ccttcagcat ctttttgtga aatcgcaact tctgcttgct
    16321 gggttaattc tcccaaggca tgcaaaaacg gtagggcatc cttgccctta ttttgaacca
    16381 cttggatggc ttcacgagta tgaccataaa cacccgtatc ggcaatcacc aaataggcgg
    16441 ataaatccat ctcaagttct gtaaatccta cgttcttgat aaagcgaata ggttggtcac
    16501 tgagacaggt cttagcatcc aaaccactag gattcatatg agcaatcatc tcagctcgat
    16561 tgaccaagat ttctagtaca tcatgaggca gatcagcctg atagtagtca aataccgcac
    16621 gaatggccgc tatgctgata gccgctgacg aacccatccc ccgtttctca gggatagccg
    16681 agtcaatctc acaacgaacg caggtttctg tgatatccaa atactccagt gaagcataaa
    16741 ccgccatgga caaggtatcc tcctcataaa ggcgccaagg actctctgca ggaactacct
    16801 tacaggtcac ctccacctcc aaaagaggca gggaaatggc aggataaccg taaacgaccg
    16861 catgttcccc tattaaaatt atcttactat gtgcctgacc gacaccaact ttttttgtca
    16921 ttttttcctt ttactagacg aaaaaacgtc ttatttttca tacaagtatt aattctttcc
    16981 tatctatttt attatatttt cacaaaaaaa gcgattgttt ccattcacaa tcgcttcttt
    17041 cattattgaa cccattcgcc attataattg acaaaatagc catctacggt cgtattcact
    17101 gccaaggcac ctgagctata agcgtagtac catctgccat tgacctggaa ccaacctgtc
    17161 gtcatagaac gacgaaagaa actccatacc attaagtaaa gaggaaagtc gtgagggagc
    17221 atgcgccatt gacaacctgt tttagtgacg tacaaagtct cattaacaag tactcgtttc
    17281 ggtcatttat aggtgcggtg tttggagaaa tagggttcaa tcttagccca ttcttgatcg
    17341 tttaaatcag tatcatatac tttgcgtgtc ataactctag tttaacattt tttgtgaata
    17401 caggttctaa ataatcgacc acgaaaattt cttaagtgga aaacgcctta tgaagtatgc
    17461 tacgggaaag ttatgcactt aatttgacaa ttcaagatgt aaaaatatat actatagtag
    17521 attgaaacta gaatagt
//
LOCUS       DAVLAQ010000036        17327 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000036 DAVLAQ010000000
VERSION     DAVLAQ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.036"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(73..1029)
                     /locus_tag="VXB71_001358"
     CDS             complement(73..1029)
                     /locus_tag="VXB71_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451465.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            complement(1032..2090)
                     /locus_tag="VXB71_001359"
     CDS             complement(1032..2090)
                     /locus_tag="VXB71_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451466.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            complement(2083..3618)
                     /locus_tag="VXB71_001360"
     CDS             complement(2083..3618)
                     /locus_tag="VXB71_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451467.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGAINADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            complement(3762..4814)
                     /locus_tag="VXB71_001361"
     CDS             complement(3762..4814)
                     /locus_tag="VXB71_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0451468.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            complement(4905..5294)
                     /locus_tag="VXB71_001362"
     CDS             complement(4905..5294)
                     /locus_tag="VXB71_001362"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0451469.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            complement(5281..5943)
                     /gene="deoC"
                     /locus_tag="VXB71_001363"
     CDS             complement(5281..5943)
                     /gene="deoC"
                     /locus_tag="VXB71_001363"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0451470.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            complement(5961..7238)
                     /locus_tag="VXB71_001364"
     CDS             complement(5961..7238)
                     /locus_tag="VXB71_001364"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0451471.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            complement(7235..7816)
                     /locus_tag="VXB71_001365"
     CDS             complement(7235..7816)
                     /locus_tag="VXB71_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0451472.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            complement(8032..8435)
                     /locus_tag="VXB71_001366"
                     /pseudo
     CDS             complement(8032..8435)
                     /locus_tag="VXB71_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8626..9546
                     /locus_tag="VXB71_001367"
     CDS             8626..9546
                     /locus_tag="VXB71_001367"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0451473.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            9614..9850
                     /locus_tag="VXB71_001368"
     CDS             9614..9850
                     /locus_tag="VXB71_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0451474.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            9903..10427
                     /locus_tag="VXB71_001369"
     CDS             9903..10427
                     /locus_tag="VXB71_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0451475.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(10450..11160)
                     /gene="deoD"
                     /locus_tag="VXB71_001370"
     CDS             complement(10450..11160)
                     /gene="deoD"
                     /locus_tag="VXB71_001370"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0451476.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(11818..12330)
                     /locus_tag="VXB71_001371"
     CDS             complement(11818..12330)
                     /locus_tag="VXB71_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0451477.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(12355..13335)
                     /locus_tag="VXB71_001372"
                     /pseudo
     CDS             complement(12355..13335)
                     /locus_tag="VXB71_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(13811..14620)
                     /locus_tag="VXB71_001373"
     CDS             complement(13811..14620)
                     /locus_tag="VXB71_001373"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0451478.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(14644..15177)
                     /locus_tag="VXB71_001374"
                     /pseudo
     CDS             complement(14644..15177)
                     /locus_tag="VXB71_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285096.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(15179..16390)
                     /locus_tag="VXB71_001375"
     CDS             complement(15179..16390)
                     /locus_tag="VXB71_001375"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0451479.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(16404..17087)
                     /gene="rpiA"
                     /locus_tag="VXB71_001376"
     CDS             complement(16404..17087)
                     /gene="rpiA"
                     /locus_tag="VXB71_001376"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0451480.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
BASE COUNT         5201 a         3971 c         3089 g         5066 t
ORIGIN      
        1 ccaaaagtta gattttttct gtctaacttt tggggggcag ttcagtcatt ggactgacgt
       61 ttttttgtat gcttattttg atttgatgta gttgatacca tctgcttttg gtgcgactgc
      121 ttttccaaag aaggctgcta agacaagaat tgtcaaaaca taaggtgcaa tttgaagata
      181 aaccgctggc actccttgta ggaacggcaa ttgagaaccg ataacagcca aactttgtga
      241 aagtccaaag aagagactag aaagcatagc accgattgga ttccatttcc caaagatcat
      301 cgcagcaagg gcgataaatc caggtccaac aatagttgtc actgagaagt taactgagat
      361 tgattgcgca taaatcgctc cgccaattcc acctagaaaa cctgaaataa taacccctaa
      421 atatctcatc ttgtagacgt tgattcccaa ggtatccgct gcttgaggat gttcaccgac
      481 agagcggaga cgaagaccaa attgagtctt aaagagaata aaccaagcaa ggaatgagaa
      541 ggcaatcgcc agataaccaa gtagactagt tgacttgaag aagatatcac caatcactgg
      601 gatatttgcc aagactggga aatcaaagcg tccaaaagtt tgacttaggt tgtcggtttg
      661 tcctttgtta taaagaactt taactaagaa aacagccaag gcaggcgcca tcaagttcaa
      721 taccgtaccg ctgacaacat ggtctgcacg gaaatgaacc gtcgctgctg cgtggatgat
      781 agagaaaaca ctaccaacca atcctgctac aagcaaggat agccatggag ttgctgctcc
      841 aaattgttct gcaaattcaa ggttaaagac aactccagaa aaggcaccca taaccataat
      901 tccttcaagg ccaacgttta ccacaccacc acgttcagag aaaacaccac cgatacttgt
      961 aaagatgaga ggtgctgagt aaatcagcat agaagacacc aagaggggga gcaaggttat
     1021 aatagacatc tttacttacc tcctttaact tgttttttcg gtttgacaaa gcgttcgata
     1081 aggtaatgaa cactgacaaa gaagataata gacgctgtta caatgctgac gagctcagat
     1141 ggtacctgcg ccgcattcat accaggagcc ccaacttgga gaacgccaaa taggaaggct
     1201 gcaaagagta taccaattgg tgagttggcc gcaagcaaac taaccgccat tccgttaaat
     1261 ccgatagcta atgacgaacc ttgaacatag acgttctgga aggttcccaa accttcaaca
     1321 gctccaccaa gacctgccaa ggcacctgaa ataatcatag ataggataat agtccgcttg
     1381 gcagaaatac cagcatattc tgaagcatgt ggattaagac caactgcacg gatttcaaaa
     1441 ccaagagttg ttttcttgag catgaaccaa ataactgcaa cggcaatgat ggcaaagaaa
     1501 ataccaatat tcatccgtga gttaccagtc aactcagcta accaaggtgt ctgataggtt
     1561 gcattagccc caacacgaat ggtcgaatct gtactttgca tgaagtcttt agggaaagca
     1621 tggataaagg cattccctac atacaagaca atgtagttca tcatgatggt tacaataacc
     1681 tctgacgtcc ctagataggc cctaagaata cctggaatcg ctccgacaat cccaccagca
     1741 atcaaggcaa tcacgatggt tgctagaatc atcaagggac ggggcatatc tggatgcgac
     1801 agggcaaacc aaccactgag aatccaacct gccaaagcct gaccaggaag tccgacgtta
     1861 aagaaaccag ctcgactggc aaccgcaaaa ccaagaccaa tcaagaccag aggacccata
     1921 gcacggaaga tttctccaat cccacgcaga ctgccaaagg ctgtatagaa caattcttcg
     1981 tagccccaaa tagcatcata accgaagatc cacatgacaa tggctccgag taaaattcct
     2041 aggaatacag aaatcaaggg aaccgaaatt tgttgtaatt ttttagacat cactcttctc
     2101 ctttcccaag tttccaccag ccatcaagac accaagtcct tgtttattgg ttgtttctgg
     2161 tgatacaata ccttgaatct taccatcgtg gataacggca atacggtctg agacgtttaa
     2221 aatctcatcc aattcaaagc tgacaacaag gacagccttg ccattatcac gctcttcaat
     2281 caagcgtttg tggatatact caatggcacc gacatccaac ccacgagttg gctggctaac
     2341 gataaggaga tcaggatctc gatcaatttc acgagcaata attgcttttt gttgatttcc
     2401 tcctgagagt gcagctgcag gaactaattc actggcagcg cgaacatcaa actcttccat
     2461 cagcttttta gcataagaag taatatttga ataattcaaa attccatttt tactatgtgg
     2521 ttctttatag taggtttgaa gggcaatatt ttcagatatc atcatttcca aaatcaagcc
     2581 atcacggtga cggtcttctg gaacgtgccc aacacttagt tctgtaatct gacgtgggtg
     2641 caagcctaca attgaatctc cttttagctc aatgctacca gattcaacct tacgaagacc
     2701 tgtaatggct tgaatcagtt cagactgacc atttccatca atccccgcaa taccaacaat
     2761 ctctccagca cgaacatcca aggacagatt tttaacagct ggaacaccac ggttttcatt
     2821 gaccaccaaa tctttgatag acaaaaccac ttcttttggt ttagaggctt gcttctctgt
     2881 tttaaaggaa acagaacgtc ctaccatcat ttccgccaaa tcagcattga tagcccctgc
     2941 aatttcaacg gtttcaattg atttcccacg acggataact gtaacacggt cagaaactgc
     3001 gcgaatttca tccaatttgt gggtaatcaa gataattgat tttccttctt tgacaagatt
     3061 tttcataata gccatcaact catcaatttc tgatggagtc aaaacagccg ttggttcgtc
     3121 aaagataagg atatcagccc cccgataaag tgtttttaaa atttctacac gttgttgggc
     3181 tccaactgag atatctgcta ccttggcaga agggtcaaca gctaagccat aacgttcaga
     3241 aagagccttg atttctttgc tagctccagc gatatctagc acaccatttt tagtcaattc
     3301 actacctaaa atgatgtttt cagccactgt gaaggcttca accaacataa agtgctggtg
     3361 aaccatcccg attcccaagc tagctgcttt agatggggag tcgagattga caacttgacc
     3421 gttgaccgcg atttcaccac tggttggttc aagaaggcct gctaacatgt tcattagcgt
     3481 ggacttacca gccccatttt ctcctaaaag tgcatgaatt tcaccttttc gtaggtgcaa
     3541 gttgattttg tcgttggcaa caaatccacc aaacaccttg gtaatatcac gcatctcaat
     3601 gacattttcg tgtgccatgt gctcttcctt tcagagtctt attttatttc aataaaactt
     3661 gctagtttgt ctagtagcaa gctttactga gacaaaatga ctttgtctca actcttaaaa
     3721 aagcggccct tggccgcttc ctaagaaatg acttccatcc attatttttc aggaactttt
     3781 acgcttccat caaggatttt agcttttgca tcttcgacag cttttttacc ttcttctgaa
     3841 aggtttgtta ctgccaagtc aaccccttta tccttcaatg agtaaacgat cacttgaccg
     3901 ccagggaatt ctcctttttc tgccttgtta gaaatatctt ttacagttgt accaacttgt
     3961 ttcaaagtag atacaagaac aaagtttgat tctttgccat ctttagaagt gtatttacct
     4021 tctgcttctt ggtcacggtc aacaccgata acccaaactt tttcattttc aggacggctt
     4081 tcgttgagag attttgcctc tgcaaagaca cctgcacctg taccaccagc tacttggtaa
     4141 acaatatctg caccggctgc gtattgtgcg gctgcaattg ttttaccttt agccgcatca
     4201 ccaaatgaac cagcgtagtc aacttgtact ttgatagatg ggtctactga cgcaacacca
     4261 gccttgaatc ctgcctcaaa acgagagata acttcagatt cgataccacc tacaaaacca
     4321 acttgttttg tcttagttgt ttttgctgca gccacacctg caaggtaacc tgactcatta
     4381 tcagcgaaag ttacgctcgc aacatttttt tggtctttaa tcacatcatc aatcaagaca
     4441 tagttcaagt cagtgtgttc tttagctgct tcttcaactg cattgtgaag ggcaaaacca
     4501 acaccaaaga ttaggttgta acttccagcc gcttgttgca agttgttagc gtagtcagct
     4561 tcacttgttg attggaagta agtgaaaccg ttatcttttg aaagattgtg ttctttaccc
     4621 cagtcttgca aaccttccca agctgattgg ttgaatgatt tgtcatcaac accaccagta
     4681 tcagtgacga ttgctgcttt tgtcttcaca tcagaagatg aagctgcgtt acgagaagag
     4741 cggttaccac atgcagcaag tccaactgct gccactgcaa ctaggccaag acctagccat
     4801 tgtttcttgt tcattactga acctcctaaa taagatgtgc aacgatgttg caagtatgga
     4861 ttgattggtc acaaagaccc ttgccactca aagagcgact cagactaatt taagtctgta
     4921 aaagagtatg gaagtaactc cccgaccgtc atctcgaccg tcgatttatc ttttgcgact
     4981 agggtcactt ttaaatcttg ttcaaaaaat tcgaccatta cttggcgaca agcaccacat
     5041 ggtgaaatcg gtttttcagt ttgaccatag acaatcaatt ctgaaaattc tctttggcct
     5101 tcagatatag ccttaaaaat agctgttctc tcaccgcaat tggtcaaagg atagctagca
     5161 ttttcgatat tcactcccgt gtaaacactt ccgtctttgg ctactaaaac tgctccgata
     5221 ggaaagtgag aataggggac ataggcatgt ttgctggttt caattgccag ttcaatcaac
     5281 tcagtagtcg ccatctgcca attctccttt taaaatagct accccagctg acgttccgat
     5341 acgggtcgca cctgcttcga caaaggtaag agcatctgca taagaacgag ctccaccggc
     5401 ggccttgaca cccatatcag gtccaactgt ttcacgcatt aatctaacat ctgctatcgt
     5461 agcaccacca gttgaaaagc cagtagatgt tttgacaaag tcagctcctg ctttttgggc
     5521 taattggcaa gccaaaactt tttcttggtc tgtcagaagg caagcttcaa taataacttt
     5581 cactaacttg tccccacttg cttccactac tgcacgaata tccgactcaa ccaaggccaa
     5641 atcacctgac ttgagagccc caacattgat taccatgtca atctcatcag ccccattttg
     5701 gatagcttct tttgtttcaa aagctttcac agttgaagtt gttgctccca aggggaaacc
     5761 tactactgtg caaaccttaa catctgtgcc ttcaagtcct tttttagcat gttcaaccca
     5821 ggtcggatta acgcaaacac tggcaaagcc atactctcta gcctcagaca acaaactatc
     5881 aatttgtttt ttctttgcat cttgttttaa aagcgtatga tctatatatt tatttaattt
     5941 catttcggtt ttccctccat ttaggagatg atttctacaa tttcacggat ttttttcact
     6001 tcatcactta ttttaacaca tttttggaaa tctgtaacta gttgaggtgg aattttttca
     6061 tttgtgtata cttttgcaac aatttcaccc ttttgaacgg agtctccaat cttcttttca
     6121 aaaacaattc ctgtttcata gtccaagaca tcagacttaa ctgcacgacc agcacccagc
     6181 ctcatggcat aaagaccaaa gtccatagct ggaagagctg aaatgacacc cgtttcctga
     6241 gcagggattt ccaccacatg agctacattt acaggacgat agaggtcttc caagtctcca
     6301 ccttgggctt gcaccatttc ctcaaactta gccagtgctt gaccattttc aagatgttgg
     6361 cgaacttctt caacagtttt gttaacattt gccaaaccaa gcataatttg agccaattca
     6421 caaataaagt gggtaatatc ctgacgtcct tgaccttgca aaatctccaa tgcttcaagg
     6481 atttccagac gatttccaat cgctcgcccc aaaggctggc tcatatccgt aatcactgct
     6541 actgtcttcc gtccaacaac cttaccaaga tctaccatag tttgagccaa ctcacgcgcc
     6601 tcatcaaccg tcttcatgaa ggcaccctca ccgacagtca cgtctagcaa aatagcatcc
     6661 gcccctgccg caattttctt gctcatcacc gaactcgcaa tcaaaggaat cgtgtcgaca
     6721 gttgcggtca catcacgaag ggcatagaga agcttatctg ctttgaccag ctggtctgat
     6781 tgcccaatga cagatactcc aatatcctga acctgacgaa taaaatcctc ttgactacgt
     6841 tctacttgat agcccctaat ggactccaat ttatcaattg ttccgcctgt atggccaaga
     6901 ccacgaccac tcatttttgc tacaggcaca ccgaagctag caacaagagg agctaaaatc
     6961 aaggttacct tatcgccgac accaccagta gaatgcttgt caactttcac accatcaatg
     7021 gctgacaggt caaactcttg cccagtctta accatattca tcgttaaatc agagatttct
     7081 cgagtcgtca ttcctttaaa ataaacagcc atagcaaagg cagacatctg ataatcagga
     7141 acagttcctg atacatagcc ttctatcagc cattcaattt cacttgaagt cagttcttga
     7201 ccgtctcgtt ttttttggat taaatcaact gctctcattc tttcacactt ctaaggatat
     7261 agtatccctt gtctttttta aggatttcac aattgccaaa cacatcttcc atcttagatt
     7321 tggcacttgg agctccttgt tttttctgga tgacgatggt caaatctcca ccaatttcca
     7381 agaaatcttt acttttctcg atgatttcat gaacgacttg cttgcccgca cggataggag
     7441 gattggaaat gacatggtca aatcgccctt gaactcttgc ataaatatta gattgaaata
     7501 tcgtcgcttt tgcattattt ttttcagcat ttctctgagc taaatccagg gcacgagtgt
     7561 taatatcaac catggtcgcc tgaactccgt aaaccttgac caaggacaaa cctaatggac
     7621 cataaccaca gcctacatct aggactgtct ctccttggtt gacatccaga cacttgagca
     7681 agagttgact tccaaagtca accattttct tgctaaaaac acccgcatct gtcaaaaaag
     7741 tcattttttc tcccaacaag tccactctca actcatgaat gtcgtgagca gcgtcaggat
     7801 tttctgcata gtacatttta ctcatgacac tattttacca taatttgact caaattgtaa
     7861 atcgtttaca aattgataat aaaacgaaaa agaccgaaga aagcaagtca cgaagccatt
     7921 ttcttcaatc tctttcaaca cttataaata ataaaccatt tagaactata aatatcacag
     7981 tccagataaa aacaaaaagt ttatcatcta taatcaggca gattattatt tctattgctt
     8041 aaccttaaaa tactttatta tcaacaaaat tcctaacaaa atgtttagat aaaagcccaa
     8101 ctgatacgtt tgtgtcagga tttccaaact tgtccaaagt cgtatcaaat cttctagtga
     8161 catgtggaag aaataaccct ctgtcgcaat ccgtaggact aaaaagcaat aactacccgc
     8221 agcaatccat ttcgtccatc gttttttagt aagaaagcaa ttaagaacga acagataaag
     8281 acagctgtta caatagcatg ttccatcaaa aaagtaaaac cgtaataggt ttccacaaag
     8341 catctaccat tatctgcatt ggttcctttt ataaaaggta aagcaaaact taaaataaaa
     8401 cagagttcca atatataacg ttttaagatt ttcatagtac acctcctact aagttgtgaa
     8461 ctaaaaagcc ccctttataa gcttataaat cagtagaatc tatctcctat ttcatcaata
     8521 aattgatcac ttatactata taccattgac ttaccacatt caagaaaccg ctttattttt
     8581 ttagcttttt atggtatgat agacaaaata tctaggggaa aacaaatgac caacgaattt
     8641 ttacattttg aaaaaatcag ccgccagact tggcaatctt tacatcgaaa gacaacacct
     8701 cctttgacag aagaagaatt ggaatctatc aagagtttta atgaccaaat cagtctccaa
     8761 gacgttacag atatctatct ccccttggct catctgattc agatttacaa gcgaactaag
     8821 gaagatttag ccttttcaaa aggaattttc ctccaacgtg aaagtaaatc tcaacctttt
     8881 attattgggg tttctgggag tgttgccgtt ggaaaatcca caaccagtcg cctacttcaa
     8941 atcctactgt cccgtacgtt tacagatgct acggttgagt tggttacaac tgatggtttt
     9001 ctctatccca atcaaacctt gattgagcag gggattttaa atcgtaaagg atttcctgaa
     9061 agctatgata tggaagctct tctcaacttc ttggaccgca tcaaaaatgg acaagatgta
     9121 gatattcctg tctattctca tgaagtttac gacatcgtac ccgaaaagaa acaaagtgtc
     9181 aaagctgctg attttgtaat tgttgaggga attaatgtct ttcaaaatcc acaaaacgat
     9241 cgtctctata tcactgactt ctttgacttt tccatctatg tagatgctgg agtagatgat
     9301 attgaaagtt ggtatctgga ccgtttcttg aagatgctga gcctagccca aaacgaccct
     9361 gatagctact attatcgttt tactcagatg ccgattgggg aagtggagtc ctttgcccat
     9421 caggtctgga tcagtatcaa tctcacaaat ctgcaaaatt atattgaacc aaccagaaat
     9481 cgtgcagaag tgattcttca taaaagcaag aaccatgaaa tcgatgaaat ttacttaaaa
     9541 aagtaatttt cccttgtcaa aacgtaagtt ttcatatata atggtatagt tagtaaatat
     9601 ggaggtaaga acattggcaa acattaaatc agctatcaaa cgcgctgaat tgaacgttaa
     9661 acaaaacgaa aagaactcag ctcaaaaatc agctatgcgt actgctataa aagctttcga
     9721 agcaaaccca tctgaagaac ttttccgtgc tgctagctca gctatcgata aagcagaaac
     9781 taaaggtttg attcacaaaa acaaagcaag ccgcgataaa gctcgtcttt caactaaact
     9841 tgctaaataa gaaacagtcc atagaggctg tttttttgtc tccaaatagg aaaaggtaga
     9901 aaatgaaaat cacaattatc ggatattctg gttctggtaa gtcaactcta gcagaaaagt
     9961 tatctaacta ctactccatt ccaaaactgc acatggacac actccaattt caacctggtt
    10021 ggcaagacag tgactgcgaa tggatgttaa ccgagataaa aaactttctc accaagcata
    10081 aagcttgggt catcgatggt aattattctt ggtgctacta ccaagaacga atgcaagaag
    10141 ctgaccaaat catctttctc aattttttgc cattgacctg tctctttaga gcctttaagc
    10201 gttatcttaa ataccgtgga aaagtcagag aaagtatggc ggcagattgc cctgaacgct
    10261 ttgagtggga gtttatcaga tggattcttt gggatgggcg tagcaaaact caaaaagaaa
    10321 attaccaaaa actttgccaa gaatattcac ataaagtcac tattcttcga aatcagagag
    10381 agctagatca atttctggat aagaaaagga agtcctacaa ttcataaagg gcttcctttt
    10441 tggctataat tattctgcaa tcaaggtttc caaaccaacc ttcatcatat cagtgaaggt
    10501 attttgacgt tcttctgcag ttgtgtcttc gtctggattg accaagctat cagagatggt
    10561 catgatagct agcgcatcaa catggtattg ggcagcaaga tagtaaagag ctgctgcttc
    10621 catttccaca gccttgactc cccatttacc aagctcgata ttcttttcaa agtaatttga
    10681 gtaaaagaca tcagatgaca aaacgttccc aacgtgagta gtcataccaa gttctttggc
    10741 gatatggtag gctttatcaa gcaaatcaaa gctagcaatt tgtggaaaat cgtactgtgg
    10801 ccagtcatta cgaacgatgt ttgagttggt tgcagccgcc tgcgccaaaa ctaattcacg
    10861 aacatgaacc tcttcattca aagaacctgc agttcccaca cgaatcaatt tcttcacacc
    10921 gtagtctacg attaactcac gcgcataaat cgaaatagat ggcattccca tcccagttcc
    10981 catgacagat acacggtgac ccttgtaagt accagtgtaa ccaaacatgt tacgcacttc
    11041 gttaaaacaa acagcatcat caaggaaatt ctccgcaata aacttagcac gaagaggatc
    11101 cccaggaaga agaattttat cagcaatttc accctgctga gcagcaatat ggatagacat
    11161 aatttatgat acaaagagcg agaagaaaac gactgaaaat taggaagccg acgagaaatc
    11221 ctgatttttc agtcagatta tctattttcc gagttttccg ctcgtgttca aatcaaaaca
    11281 cacgctctac ctttctttat tttatatttt atattgagaa agataccaaa cccgtcaaaa
    11341 agcgaaggga aaataggagt tgggcgcagt gagcgatgct cgctagacca actatctttt
    11401 tcccactgct tttagggtgg ggtcaattcc tttctttctt aattttgatt tagaggagag
    11461 tcgcccgtat tcagttcagc gaatacagtt tacccatcct ttcgtttttg tttttagaaa
    11521 agttttctac tcgtgttcaa attagaacac gcgctctacc tttctgttta tactcttcga
    11581 aaatctcttc aaaccacgtc aacgtcgcct tggattatat atgtgactga cttcgtcagt
    11641 cttatctaca acctcaaagc agtgctttga gcaacctgcg gctagtttcc tagtttgctc
    11701 tttgattttc attgagtatt aattttgttc tttcacagag agctacctga gttctattca
    11761 agctcagata gtactttctt ataaactaga caaactaact gtcattgtac catcagatta
    11821 caagacatca tcgtcactca ccttggaatt caatgtcgta ccccaatggg taattttacg
    11881 gtggggttga gctaaaattg gtctgttttc atagattgtt tgccatctat tccatagtag
    11941 gcccgtcttt ttctcaatct taactcgcag atttctcata ttttctttga ttgggaagtt
    12001 gaggacaaaa cctgcagtct ggttgcaacc gtttccttcc caagaatgac tacgaacaac
    12061 ttggtttcca tctttatcta ctggaacttc ttcccaagtt atggagtagc gggcaatgta
    12121 agctccactg tgttgaattg tcaatgtttt atctttcaca ggagtctgac tgattggttg
    12181 aactggctta gaaacttgtg tcgccgtttc agcattcgta gctataaagc ggaaaacttc
    12241 aacttctgca agactgaggg cattatagcc ttctagccca atccgaacat agcgcgcttt
    12301 tttatggtta atcgtaattt gtgctgacac atctttagga gatattatac gttttcactc
    12361 aatttcttta ccagaactgt ctaaaagaat gacatcaaag tttgccaatc tatcctgggc
    12421 agtgtctgtt cggttgtaaa tattgatttg gcgaatggtt tcttctttag ccaaatctac
    12481 ttgccaccaa ggcttagatt ggaagtttgt atgagtgaca gaattgtgac catagttacc
    12541 atcgactttg ccatccacag ctcttctagc atctcctccg aaagctgtcg aactttgagt
    12601 aacctgtttt cctaaggcaa tattttccat tggttcagcg cttggttgac tagaagattg
    12661 aggtagagcc tgtttcttaa agaatcgcac tttatccaat ttcggatcac gataaccatg
    12721 tttatccaag gtagcttgtt taccaatatt aaagttagga atatcattca ttggactttc
    12781 aaaatagcca cgagaacggt gtttaaagcg tgaattacct gtaaatgtaa caatatcacg
    12841 attattatga atcaagggag tcacaacatt gtcattatca accacataat gcttaatttt
    12901 tccactaaca gctaatttac gactttccaa accaacatct cagaaaccat tcttagcatc
    12961 ccaaacagtt ctggaagtaa tcactttagg agcactgaaa gttgtcactt tcctcaatac
    13021 atggttataa aaatcaggat atttttggta atcttcaacc gctgcaatct gagctaggta
    13081 gcctccaaga gaatgacctg tcatatacaa cttagtaata cttatatcct tggctaattc
    13141 cccaacaacc ttgcggatgt catccgcttg agctggctct gttatctcta cttttgactc
    13201 ttcccttttg ttttcaagaa cttcacttgc ttccggaagc gtttgaggag ctagtcttgg
    13261 ctcctctcta agaggagttt ctagttttgg agcatcattt tctgactctt tcaattcctc
    13321 cttagaatct agcacaccta ttaccacttc agttgttaca tcttgcttta cttcattggc
    13381 tgaaattcca gctggagcta gaaatcaaag ccgactacaa cagatacaac tccgatactt
    13441 aattttttat gccaaagcgc ataattcgtt gaccaatttt cattatttct tatctttctt
    13501 ttcgtttatt tacaagcaga ctcaagcgaa atctcattgt gctatatatg ataagactga
    13561 gaaattcaga aagtcaattc attctcatct ctccttatca tactagtctg cttggctagg
    13621 aagctaatgc tagtatccta gaatcttgtc tttcacaatg ctggctatca gatcagacac
    13681 acctattctt ccgcttcttt cagttataag agcaggaaga agctcatagt attcctctgt
    13741 ttcttcttta atacggatag gcagtcaatc ctgaaaagac agaggcactc ccccttttaa
    13801 atcttttttc ttacaattca gcaagaatcg ctttaagcaa gcctttaaaa tcacctttaa
    13861 cacgttcagt cacttctaca acttcttcgt gattgagttc ttcttggaaa ccagccgcaa
    13921 agttagtgat acatgaaatt cccagaactt tcaagccaga gtgggctgcc acgataactt
    13981 caggaaccgt agacatacca actgcatctg ctcccagtgt cttataggaa cgaatttctg
    14041 ctggtgtttc ataagtcgga ccagtaactc cgatatagac accttcatca agcttgatat
    14101 taagtttttt agccacttca tgggcagtag cacggtattc tggtgtgtag gccctagaca
    14161 tatctgggaa acgtgggcca aagtcatcca agttttcacc catcaatgga ttttgccccg
    14221 tcatgttgat atggtctgag atagccatca aggtaccagg accaaatccg ataccgccag
    14281 ctgcattggt tacaataaca ccttcacatc caagaacttt catcacacga actgggaaag
    14341 tcaccacttc cagaggattc ccttcataga aatggaaacg cccttgaaga gccaagacct
    14401 tgcgacctgc cagttcacca tataccaatt taccagcatg accgactact gttgaacggc
    14461 cccagtttgg aatctcagca tagtctacta caactggatt ttcgatttct tctgccaatt
    14521 ctccaagtcc tgacccaagg attagaccga actcaggggc tgcaattccc ttttctttca
    14581 ggaaagtagc agtttcatgg attttgttta aaaatgtcat tgtgtgtctc ctttattatt
    14641 tttttagcat ttgaccaatt ttgtcaaagg ttttagcatt acgaatagta atgtggcggt
    14701 agaaaggcac ctcagcaagt acttatgata ggcagtctta gaataggatt cttcagaaaa
    14761 tttcccctag aaaatcccaa gttttccaaa ataaagcact tcatctttca gctctaaact
    14821 ttcaactgtc gcgatgactt ggtccacatc caaaccctca gtgtaaaaga gaaaatcttt
    14881 tcgtgccaaa tctctgctcc accaagctgg tagattttca agttccgcct caaagtcctc
    14941 tagactcagt aaagaaaagc tctgaataaa tggataatgg actgcaaaga aagtctctag
    15001 cttttcaacc aattgggctt tggaatctat cgaagtaaag aaaatattgc cactgttgat
    15061 gtagctctca accttttcca gtcccaagtt tgtcaattct tgacgaagct ccgccatgac
    15121 gaccttattc ttaccaccaa cattgatacc tctcaccagc aaagcatagc gcgtcatctt
    15181 ataccaattt atctaagaaa ctttccccaa tcatagcagt ttccacacca aagttatcgg
    15241 caacagtcgc tgaaatatct gcaaaatgtc ctactggaat gagaccattt cctttaaagg
    15301 cagggctata ggccaacaat ggaatatatt cccgagtgtg atccgttcct gcatacgttg
    15361 ggtcatttcc atggtccgca gtaatcaaga gaaggtcatt ctctctcata gctgcgataa
    15421 tttcaggtaa gcgttcatca aactcatgca agcaatcacg gtaaccgtga gcattacgac
    15481 gatggccgta aagggcatca aagtcaacta ggtttgtgaa tgagaatcct ttttcaaact
    15541 cagcaagtcc catagtcttc aatagtgtat caattccatg actatttgac ttgttgtgac
    15601 ccatgtcatg gttgatacca gcaccgttaa agatatcgtt gattttaccc acagcataag
    15661 tatcgatacc agcctcattc aatttatcca aaacagttgg ggaaaatgga gatacagcca
    15721 agtcacgacg gtttgccgta cgagtgaagt tacctggttc acctacataa gggcgagcaa
    15781 tgatgcgacc aagaagggca ggacgctcaa gggtaatcga acgagcgtat tcacagatac
    15841 ggtacaattc atccaaagga ataatgtctt cgtgggcagc aatctgcaaa acagggtcag
    15901 ctgaagtata gataatcaac tctccagttt ccatctgacg tggtccaaaa tcatcgataa
    15961 cagccgttcc tgaataaggt ttgttggctt cacgaataac cttgcgtcct gagaattctt
    16021 cgatttttgt caggatttct tctgggaatc cgttccagaa agtatcgaaa ggctcagtaa
    16081 tgttgagtcc catgatttcc cagtgtccag tcatagtatc cttaccaaga gatacttcct
    16141 ctaattttgt tgcatatcca gttggattgc tttcagctgc tacagtctta agaggagttt
    16201 cacgaggaat atttccaaga cctattttag ccatgtttgg gacattcaaa ccaactgttt
    16261 ttgaaatgtg tcccagtgtg tcagaagctc catctggaac ccctgcattg acaaagttat
    16321 tagcatctgg tgctgcaccg attcctacag aatccagtac caccaaatga atacgattaa
    16381 atttagacat cttatgcccc cttctatttt cctttttttg aagttgaaat ctgaactcca
    16441 tcccgtccag caacgatgac cttatccacc atttggttga ataaaccatg ctccacaaca
    16501 ccaacgacat ggtccaattc ttgtccaaaa gcaattggat tttcaatgac atccaaggcg
    16561 aggtcaatga taaaattctg catatccgtc acaaaacgtt ggccgtcttt ttcacggaaa
    16621 cttggtttgt agccagctcg ttcaaaacga cgaaagacct gttctgcacc atactgaacc
    16681 acttctactg gcaatttaaa agcacctagt ttttcgacca gcttgctttc atccaccacc
    16741 caaatgtatt cttttgatgg tgtcgcaaca accttctcca tcagaagagc accaccacca
    16801 cctttgattc cattaaactg actatccact tcatctgcgc catcaactgt cacatcgaca
    16861 aagtctactt ggtcaataga tttgagtggg atattaaggc cttctgcctg tttagtggtc
    16921 acactagaag tcgttacagc tataatctgc aatccttctt ccttgatacg acgaccgatt
    16981 tcttcgacaa aataataggc agtcgagcct gttccaagtc caacgaccat tccatccttg
    17041 acaaactcag cagccttgat acctgccatt ttcttcagat tttccactca aacacctcca
    17101 ttaaagagct acctctatta taccatgtaa aggcttttat ttcatctaaa agtaccttta
    17161 gaatactgct tatttatcct tgaaattaaa tttttttaat aaaagcagaa ctctgacaaa
    17221 tcactttaag tacggatgta aaccaaatca actctaacaa aaatagattt acaagagtaa
    17281 aaaaaacgaa caaatttagt ttcttagcga gaagaatact aaacgtt
//
LOCUS       DAVLAQ010000037        17002 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000037 DAVLAQ010000000
VERSION     DAVLAQ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.037"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VXB71_001377"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VXB71_001377"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0451481.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VXB71_001378"
     CDS             1377..1886
                     /locus_tag="VXB71_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451482.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4365
                     /locus_tag="VXB71_001379"
     CDS             1963..4365
                     /locus_tag="VXB71_001379"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0451483.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAVASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4433..5434)
                     /locus_tag="VXB71_001380"
     CDS             complement(4433..5434)
                     /locus_tag="VXB71_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0451484.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5590..6036
                     /locus_tag="VXB71_001381"
                     /pseudo
     CDS             5590..6036
                     /locus_tag="VXB71_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6162..6428
                     /locus_tag="VXB71_001382"
     CDS             6162..6428
                     /locus_tag="VXB71_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451485.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6689..8938
                     /gene="metE"
                     /locus_tag="VXB71_001383"
     CDS             6689..8938
                     /gene="metE"
                     /locus_tag="VXB71_001383"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0451486.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9002..9868
                     /gene="metF"
                     /locus_tag="VXB71_001384"
     CDS             9002..9868
                     /gene="metF"
                     /locus_tag="VXB71_001384"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0451487.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10553..12766
                     /gene="pnp"
                     /locus_tag="VXB71_001385"
     CDS             10553..12766
                     /gene="pnp"
                     /locus_tag="VXB71_001385"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0451488.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDLEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            12782..13399
                     /gene="cysE"
                     /locus_tag="VXB71_001386"
     CDS             12782..13399
                     /gene="cysE"
                     /locus_tag="VXB71_001386"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0451489.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13411..14295
                     /locus_tag="VXB71_001387"
     CDS             13411..14295
                     /locus_tag="VXB71_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451490.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14382..15725
                     /locus_tag="VXB71_001388"
     CDS             14382..15725
                     /locus_tag="VXB71_001388"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0451491.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15718..16104
                     /locus_tag="VXB71_001389"
     CDS             15718..16104
                     /locus_tag="VXB71_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0451492.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16108..16992
                     /locus_tag="VXB71_001390"
     CDS             16108..16992
                     /locus_tag="VXB71_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0451493.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGFLSTIVGL"
BASE COUNT         5047 a         3321 c         3893 g         4741 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga cagctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaagggt
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttat atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggaa tcgaggtaga gggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagagcg tcagatcgtt tgcggtgccc caaatgtgcg tgctgggatc
     2221 aaggtcatgg tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga
     2281 aaaatccgtg gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct
     2341 gactcagttg tgcctaagga attcgcagat ggcatccaaa tcttgcctga agatgccgtg
     2401 ccaggtgagg aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc
     2461 acaccaaacc gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc
     2521 tatgacaagg cagtcaactt taaagaattt actctaacag aaactaatga agctgcggca
     2581 gatgcccttt ctgtcagcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     2641 gacaatgtga ccatcgcacc aagtccacaa tggttgcaaa atcttctcat gaacgaagga
     2701 atccgtccca tcaataacgt agtggacgtg accaactaca tcctgctcta ttttggtcaa
     2761 ccaatgcatg cctttgactt ggataacttt gaagggactg acatccgtgt gcgtgaagcg
     2821 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     2881 ctagtcatca ctgtcgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     2941 acagaaatct ctgaaaaatc tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa
     3001 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     3061 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggtagctag cctgattgcg
     3121 gaacttgcag gtgcgacggt gcgtaagggc atcgtttcag cgggtgagct tgatacttca
     3181 gatgtagaag tttcttcaac ccttgctgat gttaatcgtg tcctcggaac tgagctgtct
     3241 tatgctgatg tagaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     3301 agctttacag tcagagtccc acgtcgtcgt tgggatatca caatcgaagc tgacctcttt
     3361 gaagaaattg ctcgtatcta tggttatgac cgcttgccaa ctagtctacc aaaagacgat
     3421 ggtacagcag gtgaattgac agccacacaa aaactccgcc gtcaagttcg tactattgct
     3481 gaaggagcag gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt
     3541 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     3601 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     3661 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     3721 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     3781 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc
     3841 cttgaagccc tatttactcg tttgggactc caagtaacct atacagcaac atctgaaatc
     3901 gctagccttc atccaggtcg tacagccgtg atttcattcg gtgaccaagt tcttggtttc
     3961 cttggccaag tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtggct
     4021 gagcttaacc tttcagctat cgaagctgcg cttcagccag cgactccatt tgtagaaatc
     4081 accaaattcc cggcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat
     4141 caagaagttg tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     4201 tttgacgtct tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     4261 accttccaaa atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa
     4321 atccaagcat cgctcgaaga aaaagtcaat gcagaagtgc gttaaacgat agtatgatac
     4381 aaattccccc tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg
     4441 tgatttctgt aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt
     4501 taacatagta gtggttttta ggcaataaaa tatgatctat tgttgcatta aaaagttttg
     4561 gactttggct attccaagtt cctctttcaa aaggtggcag tacatttaat gcgtccctat
     4621 gagagcttat ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa
     4681 tagcctttgg atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga
     4741 tttccattaa acctggcaga ggaggagcag tatgcaaggc aatgatatct ggtatatttt
     4801 gttttctcga atgtaataca attgtcccga accgtgttgt atgaaaagtt ttagcttctg
     4861 tatagaaacc ataacttttc ttgacaatca cagtcacagg agctattcca ctattggtag
     4921 gtggagaagt gaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt
     4981 tgattctctg gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca
     5041 tatcggcgtc aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga
     5101 cgttccaagt tactaatttt aaggttttag tcttatttga tgcagaagaa agggttttat
     5161 ctgttccgaa taatagtaat atgagcgata gtaagagcaa aatgccagag taaaaccgta
     5221 tttgtttatt tttcttgtaa aaagataggg aaaaaaatac gaaacttaaa atagcagcca
     5281 tagttgcagt agctaagggg aaggcataaa tctgtgccaa gataggttgg gtagatagcc
     5341 aaatgttaag attagaagat gggaaaaaag aataagttat aatagggata gaaaagagaa
     5401 tgaccgaaag ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg
     5461 ttgctcggag ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc
     5521 ctcatagatt aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa
     5581 ggcacagaaa tgcaagacaa ttatactaca aaaggcaaac atttgacaat cgatagccgt
     5641 cgcttaatcg aacgatggaa aaaagaagga aaatcaaata gagaaattgc ctctctactt
     5701 ggaaaagctc ctcaaactat ccatactgaa atcaagtatg ggacagtccg acaatgtctt
     5761 ggaaaagggc gcttcaaaga gatttattct gccgactacg ctcaacagtc ttatgaaaat
     5821 aatcgcaagc actcggtcaa gaaatcaagc ttgactaaga aactaaagga aaagattctc
     5881 cactatcata accaaaaatt ttcgcctgaa atgatggtga tggctaaagg ggttaacgtg
     5941 ggaatttcaa ccatttacta ttggattcat cgtggaaaat tggggttaag caagcaggat
     6001 ctgctttatc ctagaaaagg aaaagcgctt aagaaatagg ctagcaccaa ctttaaaccc
     6061 gctggtcaat ctatcgaatc ataattcgct cattttttta aaaatacata gacgtaaaaa
     6121 aaagagggtt aagtgatgaa gaatagtgct attgggagta attggaagga tgtccatctg
     6181 agctctttag caaggaggaa atccttgaaa gtgatatgcg agtggctatc atgagcgagt
     6241 tgattgaggc taggtatgaa caaggaatca gtcagaaaaa gctggaagaa gtcagtggaa
     6301 taagccagcc tgtcatagct aggatggaga caggagagag cagtcttcag ttggatacgg
     6361 tcttaaaagt tctaaccagt ctaggaaaga cactagcagt cgttccactt gaacagggga
     6421 aaagttgact agaatcagtt atagtctttt ctaataacag gtcatagtca cttataagaa
     6481 ttactaataa catgttttag tattctaatt ggaatatagc tgtaaagtaa gaattacaaa
     6541 ggatttgaga cgtttgcttc aagtcttttt cttttgtccg aaacagatat atagtttcaa
     6601 actatatcaa accctaattt tttacaatta tacagacgct ttcttttctg ttaagatagt
     6661 ttcaacaaca aattttggag gacacatcat gtcaactaca atcatcggtt tccctcgttt
     6721 gggcgaattc cgtgaattaa aatttacaac tgaaaaatac tttagaaaag aaatctcaga
     6781 agaagaactt ttagcagcag caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga
     6841 aaaaggcatc actgaaattc catcaaatga cttttctcac tatgataact tcctagatgc
     6901 ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga
     6961 gcgctacttc gctttgggac gtggttacca gggagaaaaa ggggacgttc gcgcccttcc
     7021 aatgaagaaa tggttcaaca ctaactacca ctacatcgtt cctaaatttg aaaaagacac
     7081 tcaagtaaaa ttggctggtc acaagatttt cgatgagttc caagaagcaa aagaacttgg
     7141 attgaacact cgtcctgttc ttgtaggtcc attcactttc cttcaattgt cagactttga
     7201 agaaggcgtg aaagcagacg acttcgtaga tagcttagtg gttgcttacc aagaagtttt
     7261 tgctaaattg gctgaacttg gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa
     7321 agacttgaca gctgaagaaa aagctctctt cttgaacctt tacaacaaac tcttggctga
     7381 caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc
     7441 tgaccttgta aacttgccag tagatgctat cggtcttgac tttgttgaag gtaagaaaac
     7501 tcttgaactc gttaaaggtg gcttcccagc tgacaagact ctctatgtag gtattgtcaa
     7561 tggtaaaaac atctggcgca acaactacga aaagagcttg gctgttcttg agcaaatccc
     7621 agctgaaaac atcgttttga caagctcttg ctcacttctt catgtgccat ttacaactgc
     7681 taatgaagaa tttgaaccag cactcttgaa ccactttgcc tttgcagttg aaaaattgga
     7741 tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa
     7801 caaagaactc tttgcgactg agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc
     7861 tggcttgaca gacgcagact acactcgttt gccagccttt gcagaacgtg aagctatcca
     7921 agaagaagct ttcaaacttc cagctcttcc aacaacaacg attggttcat tccctcaaac
     7981 aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt gaattgtctc aaaaagagta
     8041 cgatgctttc cttgctgaaa cgattgacga atggatcaag tggcaagaag atattgactt
     8101 tgatgtcctt gttcacggtg aatttgagcg taatgacatg gttgagtact tcggtcaaaa
     8161 cttgtcagga tacctcttct ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt
     8221 aaaaccacca atcatctggg gtgatgtcac tcgtcttaac cctatcactg ttaaatggtc
     8281 tagctatgca caaagtcgta caaacaaacc tgttaaaggt atgttgactg gacctgttac
     8341 catccttaac tggtcattcc cacgtgaaga catctctatc aaggattcaa ctcttcaaat
     8401 cgcccttgct atcaaggatg aagtacttga ccttgaagct gctggtgtga aaatcatcca
     8461 aatcgacgag gctgctcttc gtgaaaaatt gccactccgc cgtagcgact ggtacgaaga
     8521 ctaccttgac tgggctattc ctgccttccg cttggtacac tcaacagtag cgccagacac
     8581 acaaatccac actcacatgt gttactcaga atttacagat atcatcccag ctatcgataa
     8641 catggatgca gacgttattt cctttgaagc tagccgttca aaccttgaaa tcttggacga
     8701 actcaaagcg aaaaacttcc aaacagaagt gggacctggg gtttacgata tccactcacc
     8761 tcgtgtacca aatgaaggcg aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc
     8821 aagcaagaaa gtttggatca accctgactg tggtttgaaa acacgtggta tcccagaaac
     8881 aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga
     8941 ttggatttct ctccatacag tggttgttca aaaagaaatc aactagaaaa ggttattaca
     9001 tatgtcacgc caaacaccgt cactctcatt tgaagtgttc cctccaaacc cagccgtggg
     9061 taatggtaac attatttcag ccttgcagga tatgcaggag ttggctcccc attttatcag
     9121 tgtaactgcc agcaataata aatttaatat caaggaaacg acggttcgtt tggctgactt
     9181 tatccaaaat gacttggcga ttccgaccat tgcccacttg ccagctattt atctaactaa
     9241 ggacaaggtt gctgaaacta ttgctgactt ggacaaagtt ggggtgcaga aaatcttggc
     9301 tcttcgtggg gatattattc cagacgtaga accacaaaag gatttccgct atgcaaccga
     9361 cttgattgag tttatcaagg aacaagcccc tcactttgat attattggag cttgctatcc
     9421 agaagggcat ccagattcgc caaatcagat ttcagatatt caaaatctta agaagaaagt
     9481 ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt gataatgagc gcttctatga
     9541 ttttcaggac aagtgtattt tggctgggat tgatgttccc attcatgcag gaattatgcc
     9601 aattctgaat cgaaatcagg ctctccgact cttgaagact tgtgagaata tccatcttcc
     9661 acgcaaattt aaagccatct tagacaagta tgagcatgac cctgagtcgc tcagagcagc
     9721 aggacttgcc tatgcagtgg accaaatcgt ggacttggta actcaggatg ttgccggtgt
     9781 gcatctctat acgatgaata atgctgatac agcaaaatac atccatcaag caacccatgc
     9841 cttgtttaat caccagtctc taggataata aaagcaaacc attcttctca ggtgagggga
     9901 atggttcctt tttaatggta aagacctcac tttttaagaa aaatatgata aaataaattc
     9961 tgtacgtact tgatacaaag atgaaggtat taaataatac aatgcattta aactgtaaga
    10021 tttaacgaca cgagtgagtc aaatcgatgt tatttgacga gagagttagt aaagcattta
    10081 gctaatcgcc cgatagcgat tagcgtgaaa gctttagata ctttagtatt aaacctttct
    10141 aatgatgtat cttgaaaact gaacttgcct acaactctgt ggaaaaagat aaatctccct
    10201 aggagcagtc gctccgtcgt tcgatttcct attttccttt gagttgcttg acggcttggt
    10261 atcttgatga cttgaatttt ggtctcattt cttaggaaaa aagataagct tcctagcact
    10321 cgtcgagtgc gacgtcacct tcctattttt ctacagaaat gttcggcaag ccgaaccgtc
    10381 caaaatatct tgtgtaattg aacacggccg aaaagctgtg taaaaaagat aaactgtctt
    10441 gtcttcatcg aagacttcgt cagtttccta tttttacttt gcttttgacg tccttggtat
    10501 cttgatcttt gtaggcaagg cgtataattt catcaatcca aaggggatta aaatggcaaa
    10561 acaagtgttt caaacgactt ttgcgggtcg tgagttaatt gtagaaactg gtcaggttgc
    10621 taagcaagca aatggctctg ttgtcgtacg ttacggtgag tcaactgtct tgactgctgc
    10681 cgttatgtct aagaaaatgg caactgggga tttcttccca ctccaagtca actacgaaga
    10741 aaaaatgtat gcggctggga agtttcctgg tggctttatg aaacgtgaag gacgtccttc
    10801 aacagatgcg accttgacag cgcgtttgat tgaccgtccg attcgtccta tgtttgcgga
    10861 aggtttccgt aatgaagtcc aagtcatcaa tacagtgctt tcttatgatg aaaatgcgtc
    10921 tgcaccaatg gctgctatgt ttggttcatc tttggcactg tctatttcag atattccatt
    10981 tgacggacca attgctgggg tacaagtggg atatgtagat ggccaaatca tcatcaaccc
    11041 aagtcaagaa caagcagagc aatctcttct tgaattgaca gtagctggaa ccaagcacgc
    11101 tatcaacatg gtagagtctg gtgctaaaga attgtcagaa gaaatcatgt tggaagcgct
    11161 ccttaaaggg cacgaagctg tcaaagaatt gattgccttc caagaagaaa tcgttgctgc
    11221 tgtcggtaaa gaaaaagcag aagtggaatt gcttcacgtg gatgctgaat tgcaagctga
    11281 aatcattgca gcctacaaca gtgacctcca aaaggcagtt caagtagaag agaaattggc
    11341 ccgtgaagct gcgactcaag tagtgaaaga ccaagtgact gccgtttacg aagaaaaata
    11401 tgcggaccac gaagaatttg accgtattat gcgtgatgtg gctgaaatct tggaacaaat
    11461 ggaacacgca gaagtgcgac gtttaattac agaagacaag gtgcgtcctg atggtcgtaa
    11521 ggtcgatgaa atccgtcctt tggatgcggt tgtcgacttc cttcctcgtg tgcacggttc
    11581 aggtctcttc actcgtggac aaacgcaagc cctttctgtc ttgaccttgg ctccgatggg
    11641 agaaactcaa atcattgatg gtttggatct ggagtacaag aaacgcttta tgcaccacta
    11701 taacttccct caatattctg taggggaaac aggtcgttac ggtgcgccag gtcgtcgtga
    11761 aatcggtcac ggtgcccttg gtgagcgtgc tcttgctcaa gtcttgccaa gcttggaaga
    11821 attcccatac gctatccgtc tagtagcaga agttttggaa tcaaacggtt cttcatctca
    11881 agcttctatc tgtgcgggaa ctcttgccct tatggctggt ggtgtgccaa tcaaggcgcc
    11941 agtagctggt attgctatgg gacttatctc agatggaaat aactacacag tattgacaga
    12001 tatccaaggt ttggaagatc actttggaga tatggacttc aaggttgcag gtactcgtga
    12061 tgggattaca gcccttcaaa tggatatcaa gattcaaggg attactgcag aaatcttgac
    12121 ggaggctctt gctcaagcca agaaagcgcg ttttgaaatc cttgatgtca ttgaagcaac
    12181 cattccagaa gttcgtccag aattggctcc aactgctccg aaaattgata cgatcaagat
    12241 tgatgtggac aagattaaga ttgtcatcgg taagggtgga gaaaccatcg acaagattat
    12301 cgctgaaaca ggtgttaaga ttgatataga cgaagaagga aatgtgtcta tctactctag
    12361 tgaccaagat gctattaacc gtgccaaaga aattattgct ggtttggttc gtgaagccaa
    12421 agtggatgaa gtttaccgtg ctaaagtcgt tcgtatcgag aaatttggtg cctttgttaa
    12481 cctctttgat aagacagatg cccttgttca tatctctgag atggcttgga ctcgtaccaa
    12541 tcgtgtagag gatttggtag aaatcgggga tgaagttgat gttaaggtta tcaaaattga
    12601 tgaaaaaggc cgtatcgatg cctctatgaa ggctcttcta cctcgtccgc caaaacctga
    12661 gcatgatgaa aaaggtgaaa agtctgagcg ccctcaccgc ccacgtcatc aaaaggatca
    12721 caaacctaag aaagaattta cagaaacacc aaaagattca gaataagaaa aggagaaatg
    12781 tatggggtgg tggcgcgaaa ccattgatat tgtaaaagaa aatgatccag cggcccgcac
    12841 cactttggag gttttgctga cttatccagg tgtcaaggcc ttggcggccc accgtctctc
    12901 gcattttctc tggaagcacg gcttcaaact attagctcgt atgtacagtc agttttggcg
    12961 cttttggact cagattgaga ttcatccagg agcccagatt gattcaggtg tttttattga
    13021 ccatggttct ggtctggtga ttggagagac agcgattgtt gaaaaaggcg ttcttctcta
    13081 tcacggagtg actctcgggg gaacagggaa agactgtggc aaacgccatc cgactgtacg
    13141 aaagggagcc ctcatatcag cccatgccca agttatcggg cctgtggaaa ttggtgaaaa
    13201 tgccaaggtc ggtgctgcag cagttgtcgt agcagatgta cctagtgatg tgacggttgt
    13261 cggtattccg gccaagattg tccgtcttca tggtaagaaa gatgagcctg ttattcacga
    13321 agtcgaagaa aaacgggagt attatgtcaa taaactcgag caggctaaag atgccagtca
    13381 cagatcgtct ggtttgtaga ggatacctat atgattcaag caagaaacaa gttaagccaa
    13441 gaggagctat ctgaggcgaa aaaagtaatt aactgttgcc aaaactatga cggtacctat
    13501 cgcgatccct atctctctaa catgcttaat tttgacccaa acatgcccgc ctttttcctt
    13561 tattatgaaa aaggcaaact tgttggttta ttaactgtct atgcagatga ccaagatgta
    13621 gaagtgacga tattggttca tccaggtcat cgccgtcagg ggattgcgcg tgcattgttt
    13681 actagttttg agagagaaac agcttctttc cccattcggt cagtcacttt tcagacagaa
    13741 cgtatttttt tagagaatca tcctgacttt gccagtaact ggggactaat cgaggatgaa
    13801 gagacagaaa cttggttagg taaggataga agaccttatc cgttagcaaa tgtttcccat
    13861 cttgaagttt tgttagcaga tagttcgtat caggatcaaa ttagtcaatt aaaatttcag
    13921 gcattttcag aggaacatga atcgagagaa gttgtggata gatatgtcgc tgaagctctg
    13981 aaggatccag aaagtcgctt atatattttg ttaaaagacg gtcaggttat tgggacttgc
    14041 acggtagatt tatcgactaa tacgaattac ttctacggtt tagcaatatc ggaacctgaa
    14101 cgtgggaaag gctatggaag ctacttagca aaatccctcg tcaaccaact aattgagcaa
    14161 aatgacaagg aatttcagat tgcagtggaa gatagcaatg taggtgccaa acgtttgtat
    14221 gaaaaaattg gctttgtcaa acagacacag gtggtttatc tgaatgagaa aggagcaagg
    14281 gattccgaag tgtagagaca ttcggactga aatttacttg agctcttagt ttagtgatga
    14341 aactaacagt tcttggattt tagctttcct gattatgatt tatgattaaa atctatgaca
    14401 ccatgtctcg tgatttgcga gaatttgtcc cgattgagga cggcaagatc aagatgtatg
    14461 tttgtgggcc aaccgtgtac aactatattc acgtgggaaa cgcccgttcg acggtagctt
    14521 ttgatacgat tcgtcgctat tttgagtacc gtgggtataa ggttgcctat atttccaatt
    14581 ttacagatgt ggatgataag attatcaacc gtgccaggga agaaggcatc acacctcagg
    14641 aggttgcgga taagtacatc gctgcctttc gtgaggatgt gacggcctta ggcgtgaaac
    14701 ctgcgactcg ccatccgcgt gtagtggagt ttatggcaga catcatccgt tttgtggaag
    14761 acttgatcga gaaaggcttt gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa
    14821 aatcccacaa ctatgctaaa ttggctaata aaaccttgga agatttggag ctaggtgctt
    14881 caggtcgtac cgatgaagaa acggctcgta aggaaaatcc tgtagacttt gctctatgga
    14941 aatcttccaa accaggtgag atttcttggg atagtccttg gggacctgga cgtccgggtt
    15001 ggcatattga gtgttcagtc atgtcgacag agattttagg tgataccatt gatatccacg
    15061 gtggtggagc tgacctagag tttccacacc acaccaatga aattgcccaa tctgaagcta
    15121 aaacaggcaa ggcttttgct aactactgga tgcacaatgg ctttgtcaat atcgacaatg
    15181 tcaaaatgtc taagtccttg ggtaacttca ttacggtaca cgatgccctt aaaactcttg
    15241 atgggcaagt acttcgtttc ttctttgcga cccagcacta ccgtaagcct atcaacttca
    15301 cggaaaaggc agttcgcgat gccgagacca atctcaagta tctgaagaat acttacgaac
    15361 aaccatttac aggaaacgtg gatgcccaag agttacaaaa ctttaaagat aagtttgtag
    15421 cagctatgga tgaagatttt aatgctgcca acggtatcac agttgtcttt gaaatggcca
    15481 aatggatcaa ctcagggaac tatgatgcaa gtgtcaagca agctcttgca gatatgttag
    15541 aaatttttgg aattgtcttt gttgaggaag ttttggatgc agagattgaa gacttgattc
    15601 aaaaacgcca agaggcgcgt gccaatcgtg actttgagac agcagaccaa atccgtgacc
    15661 aattggttac tcaaggaatt aagctccttg ataccaagga tggagtgagg tggacacgtg
    15721 attgatgtca atctcattaa cgggattgcg ctagcctttg agggagatgc ggtgtattct
    15781 atgtatattc gccgccacct catcctcaaa ggtatgacca agcccaataa actccaccaa
    15841 gaggcgacca agtacgtgtc agccaaggct caggctcgtc tgattgctct catgttggag
    15901 gagcagatcc taacggaaaa agaagaagaa atctacaaac gtggccgcaa taccaatagt
    15961 cacacaaagg ctaaaaatgc agatgtcgtg acttatcgta tgtccacggg atttgaagca
    16021 gttatgggct atctccatat gactgagaat ctggaacgtc ttgagagttt ggtttcatgg
    16081 tgcatccaaa aagtggaggg ctagaacatg agggcaaaag aactacaaga ctggtttcct
    16141 gaggctcgga tttcagacca accagtagag aaagagggct atctcacgct tcctttagct
    16201 tctcagcagt ggattttgct ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt
    16261 gcccttttga cccagcagga gcaggctcgt tcgctaaacc cttggtattc ctatctggtt
    16321 gagggcaagg gacaggcacc gcaagttttt aaaaagattc agttggttta ttgccatctt
    16381 tcttattttc agcaggaaaa tctgacttct tggctagata tgatgcggac tctttttccg
    16441 aattgtcaga cagtgctaca ggtcggagct caggattatg ttttcgtgct tcaacaagac
    16501 aaatacactt ctgtaagaga tattttgagt gatacgattg aagcggttga gtatgacttt
    16561 ggacttcgtc tttctatcat gttgggtcag gtttggtctc agacaggaca tcaagcccta
    16621 tcagacttaa tcaaagctga gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa
    16681 ggtgttcata ctttttctca gctctatctt tggagtatgg gagaaagact cgtggacttg
    16741 aagccaatta aagaatgtct acaccagatg attttggatc aagatcagat tcaggaaatc
    16801 attctctctc tttgggaaaa tagtgctgtt ctcactaaaa cagcccagca actctatctg
    16861 caccgcaatt ctctccaata caagattgat aaatgggaag agttgacagg gcttcagttg
    16921 aaagagttga ccgacctgac cttgtgttat caattgattt taggtttttt gtcaactata
    16981 gttggtttgt aaagaagtta at
//
LOCUS       DAVLAQ010000038        16533 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000038 DAVLAQ010000000
VERSION     DAVLAQ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16533
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.038"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            42..1973
                     /locus_tag="VXB71_001391"
     CDS             42..1973
                     /locus_tag="VXB71_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0451494.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            1960..3276
                     /locus_tag="VXB71_001392"
     CDS             1960..3276
                     /locus_tag="VXB71_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0451495.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFFHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            3451..4437
                     /locus_tag="VXB71_001393"
     CDS             3451..4437
                     /locus_tag="VXB71_001393"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0451496.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCVKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4501..4572
                     /locus_tag="VXB71_001394"
     tRNA            4501..4572
                     /locus_tag="VXB71_001394"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4534..4536,aa:Arg,seq:ccg)
     gene            4755..5453
                     /locus_tag="VXB71_001395"
     CDS             4755..5453
                     /locus_tag="VXB71_001395"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0451497.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5444..8983
                     /gene="smc"
                     /locus_tag="VXB71_001396"
     CDS             5444..8983
                     /gene="smc"
                     /locus_tag="VXB71_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0451498.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8980..9774
                     /locus_tag="VXB71_001397"
     CDS             8980..9774
                     /locus_tag="VXB71_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0451499.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            9774..10592
                     /locus_tag="VXB71_001398"
     CDS             9774..10592
                     /locus_tag="VXB71_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0451500.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10596..11873
                     /gene="ftsY"
                     /locus_tag="VXB71_001399"
     CDS             10596..11873
                     /gene="ftsY"
                     /locus_tag="VXB71_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0451501.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11919..13406)
                     /locus_tag="VXB71_001400"
     CDS             complement(11919..13406)
                     /locus_tag="VXB71_001400"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0451502.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(13555..14295)
                     /locus_tag="VXB71_001401"
     CDS             complement(13555..14295)
                     /locus_tag="VXB71_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0451503.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14295..16460)
                     /locus_tag="VXB71_001402"
     CDS             complement(14295..16460)
                     /locus_tag="VXB71_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0451504.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT         5185 a         2927 c         3640 g         4781 t
ORIGIN      
        1 atgccaatat ttaaacatca ttagtaaaag gagttagatt gatgaataaa agaaaagtta
       61 gtttagaaga tttttataaa tggtatagtc taaataaaga agagttatta aataaggcaa
      121 ctgttggtga aaagtttaat gataaattaa aagaagagtt tctccaggaa tggcctttgg
      181 ataggatttt aacaatgtca atcgatgaat atgtaatagg aaagggacag caaaataagt
      241 ctttatgcta cgctcttgag aagggaaaat acaaaaatct atttcttgga atttctggtg
      301 gctcagcttc aaaatttggt atttattgga ataaaaaaac aaacaaatat aaagatcaag
      361 ctaataatga gatttcagag ttggatcagc gattttcaaa attaaaatca gatttgtatg
      421 aaattatcaa agaaggtatt cgttttaact ttgaaaatcc tatttttgat atgaaaagat
      481 caacaaatga atttattggt cgttctgcta tggtgacaaa attactttgt atctatactg
      541 agggagatcc tttctttggt gtaaatatta atagtcagaa agaattttgg aaccactttg
      601 tttctcagac aaatcaaggt ggaccttatc tgcaaaatca taaaataatt gaactagtgt
      661 ccaaaactta tcctgagttg gagccatcga aattaggaac tatgcttttt gagtattcta
      721 agctttttat ggaaaataag gaagacaata gtacaatgga ttcatcaaac aattttcgtc
      781 atcaattaac tcaatctcta ttaaagtctc caaacctcat cctccgtggt gctcctggca
      841 caggaaagac ttatcttgct aaagaaattg ccaaagaatt aacggatggc aacgaagacc
      901 aaatcggatt tgtacaattt cacccatcct atgattatac ggattttgta gaaggtttaa
      961 gaccagtatc aaatggggat ggagctattg agtttaggct acaggacggt atttttaaag
     1021 atttttgtca gaaagcaaaa gaaacccaat tgattggagg acaagataat tttgatgagg
     1081 cttgggattc ttacttagaa tatataaatg ttgctgaaga aaaagaatat ataacaaaaa
     1141 catcttactt atctattaat agtagacaaa atttgtcagt aaattatgat agtggtgttt
     1201 caggatggtc actacctagc aaatatgttt acgagttgta taaagataaa aattataata
     1261 agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga aacattgaga aagagatttg
     1321 gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga taagaaattc gtcttcatca
     1381 tcgatgaaat caatcgtggg gagatttcta agatttttgg cgaactcttt ttctctatcg
     1441 accctggcta tcgtggtgaa aaaggaagtg tttctaccca atatgcaaat ctacacgaaa
     1501 ctgatgaaaa gttctatatc cccgaaaatg tttacatcat cggaactatg aatgatattg
     1561 atcgttcagt ggataccttt gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta
     1621 ctgccgaggg tcaagttggc atgttggata aagagctgaa tatccatgca gaagaagcaa
     1681 aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt
     1741 atcatattgg accaagttat tttcttaagt tgaaggatgt agattttgac tatgaattac
     1801 tctggtctga ttatattaag cctctcctag aagactactt gcgaggttct tatgatgagg
     1861 ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac aaataatgag caaaaagatc
     1921 aggcagtagc tgatgacaat gaaggtgatg aaaacgatga tgcggattac tgataatcaa
     1981 cacaagatta ttaaagaaaa atttgttgaa gaatatccta aactaagcaa tcttctttta
     2041 gacagaacct tggaaagtct atcccaagat gaacgtattt tcatttttcc aaatgatttg
     2101 actcatactc ctgatttgga taaggaccaa aagatttttg aaacagtcaa tcagaaaatc
     2161 aagacaggga acgtgattgg ttttcttgga tatggtcagg aaagattaac gatttcctca
     2221 cgattttctg atgagagtaa tgaccatttt ttgcattatc tcttaaacaa ggttctttat
     2281 atcaatctca ctagtttaga tgttgctttg tctcgtgaag agaggcttta tcaacttttg
     2341 atgtatctct tccccaagta tctacaagct gctattcgaa aaggtcttta taaggaatat
     2401 catcgatttt ttcataacga cagtaatgtt aagggagtga ttgatgtaag aagccatctc
     2461 aagaaaaatc ttcctttcac gggaaatatt gcctacgcaa cgagagagtt cacctatgat
     2521 aatcccctca tgcagttggt ccgtcacact attgaataca ttaagaatca gaaaagcatt
     2581 ggtcaagggg tactagataa tctctcaact agtcgtgaaa acgtatctga aatcgtgcgt
     2641 gtaacgccct cttataaact agctgatcgt gctaagatta ctcggagaaa tcaatctaaa
     2701 cctatacgtc atgcatactt tcacgagtac agaaacttac aagaactttg tctgatgatc
     2761 ctaaaccaag aaaagcacgg tttagggtat caagatcaaa aaatctatgg tattctcttt
     2821 gatgttgcct ggctttggga agagtatgtt tacaccttgt tgccaaaagg ttttgtacat
     2881 cccagaaata aggataagac ggatggaatt tcagtatttt ctgttgggaa acgaaaagta
     2941 tatccagatt tttatgacag agaacgaaag attgttctag atgcaaaata taaaaaactg
     3001 gaattgactg aaaaaggaat caaccgtgag gacttattcc agctgatttc ctattcttat
     3061 attttaaaag ctgagaaggc tggactgatt tttcctagta tggagcagtc agtaaatagt
     3121 gaaataggaa aagtagctgg ctatggagct caattgaaga agtggtctat tcgaatccct
     3181 cagaatgcct catcctatag tgcattttgt aaaatgatgg aaaattcaga agaaaatttt
     3241 aaagcgatta ttgatgaaga agtggggaga aaataatttc ccctctttct tttattttta
     3301 acacaagtaa aacccgaacg atatatttta attcataaaa aaaattgaca aaaactgtac
     3361 tttggtttat aataaattaa ggaaacgtcg gaaaaggcgt agtgatgcga gagcataggt
     3421 aggtcattac aaaagaaacg agacatcgat atgttaaatg aatttccaat ttttgattac
     3481 gaagatattc aattgattcc aaataaatgt gtcattaaaa gccgtgcaga agcggataca
     3541 agtgtcactt taggaaatca cacctttaaa ctacctgttg tgccagcgaa tatgcagacg
     3601 attttggatg aaaatgtagc agagcaactg gctaaaggtg gttacttcta cattatgcac
     3661 cgttttgatg aggcaggacg cattcctttt attaaacgaa tgcacaatca agggctcatt
     3721 gcttccatat ctgtcggtgt taaggactat gagtatgatt tcgttagaca gctcaagact
     3781 gatgctcctg agtatatcac tattgatatt gctcatggtc atgcggatag cgtgatttct
     3841 atgattcaac acatcaagaa agaattgcca gatacctttg tcattgctgg aaatgtggga
     3901 acaccagaag ctgtgcgtga attggaaaat gctggtgcgg atgctactaa ggtcggaatc
     3961 ggtcctggta aggtttgtat caccaaggtt aagactggtt ttggtacagg tggttggcag
     4021 ttggctgctc tacgctggtg tgtcaaggct gcgcgtaaac cgattatcgc tgatggagga
     4081 attcgtactc acggtgatat tgccaagtct atccgcttcg gtgctagcat gatcatgatt
     4141 ggttccctct ttgcaggaca tattgaaagt ccagggaaaa cgattgaagt cgatggtgaa
     4201 cagttcaaag aatattatgg ttcagcctca caatatcaaa aaggtgctta caaaaatgtg
     4261 gaaggcaaac gtatcttgct tcctgctaaa ggtcatctgc aagacacttt aactgagatg
     4321 gaacaagacc ttcaaagtgc tatttcttat gcaggtggac gtcaggttgc tgaccttaaa
     4381 cacgttgatt atgtgatcgt gaaaaactcc atctggaatg gggatgcttc ccactaagac
     4441 ggggtctttg actaaaaaac ttgttattag agcaaatttc tgttataata aaacaagttt
     4501 ccacccttag tgtaatggat atcacgtaag attccggttc ttgagatggg ggttcgattc
     4561 cctcagggtg gatgtaaaca ttctaaaaag cctttaatag ggcttttttc tttacactgc
     4621 tctaaattta ccgctaaaac tgagaatctc tgtctaaaga atttccaaat gctttccagt
     4681 cccgttttag agtgactcag ggggcttttt ttgatataat aaaaaggact gttatcagtt
     4741 agaaagaggt tggtatgaaa gaattacaaa ctgtactaaa gaaccatttt gcaatcgaat
     4801 ttacagacaa aaagttactg gaaactgcct ttactcatac gagttatgcc aatgagcacc
     4861 gcctcttaaa aatttcacat aatgaacgct tggaattttt aggagacgct gttctacagt
     4921 tattgatttc agaatatctg tataaaaaat atcctaaaaa gcctgaaggt gacctatcaa
     4981 aactccgtgc tatgattgtc cgtgaggaga gtttagctgg ttttgcgcgt gattgccagt
     5041 ttgaccagtt tatcaagttg ggtaaagggg aagaaaaatc tggtggtcgc aatcgtgaca
     5101 ccattcttgg tgatgccttt gaagcctttc ttggtgccct tcttttggat aaggatgtgg
     5161 ccaaggtcaa ggaatttatc tatcaagtca tgattcctaa ggttgaagca ggcgaatttg
     5221 agatgattac agactataaa acccatctcc aagagttact tcaggtcaat ggtgatgtgg
     5281 ctattcgtta tcaggtgatt tctgaaacag ggcctgctca cgataaggtc tttgatgtag
     5341 aagttcttgt tgaaggtaag agtatcggtc aaggccaagg tcgttctaag aaattagcag
     5401 agcaggaagc tgccaaaaat gccgttgaga aggggctgga ttcatgtatt taaaggaaat
     5461 cgaaattcag gggttcaagt cttttgctga taagaccaag gtcgtttttg accaaggtgt
     5521 gacggcagtt gttggaccaa atggatctgg aaagtccaat attacagaaa gtctgcgttg
     5581 ggctttgggg gagtctagtg tcaagagtct ccgtgggggc aagatgccgg atgtcatctt
     5641 tgctggaaca gaaagtcgca aaccgctcaa ttatgcttct gtagttgtga ctctggataa
     5701 tcatgacgga tttatcaagg atgcaggtca agaaatcagg gtggaacgcc atatctatcg
     5761 tagtggagat agcgaataca agattgacgg caagaaagtc cgtctgcgtg atattcatga
     5821 cctcttcttg gatactggat tgggacgaga ttccttctct attatttccc aagggaaggt
     5881 tgaggagatt tttaattcca agcctgagga acgacgagct atttttgaag aagctgctgg
     5941 agttttaaaa tacaagactc gcagaaaaga aaccgagagt aaactgcagc aaactcagga
     6001 taatctggac cgcttagagg acattatcta cgagttggat aatcaaatca agcctcttga
     6061 gaagcaagct gagaatgccc gtaagttttt agacttggaa ggacaacgta aggctattta
     6121 tttagacgtt ctggttgctc aaatcaagga aaataaggct gaactagagt cgacagaaga
     6181 agagttggct caggttcaag aactcttgat gagttattac caaaagcgtg aaaaattaga
     6241 agaagaaaat caaactctta aaaagcaacg ccaagattta caggctgaaa tggccaaaga
     6301 ccaaggcagt ttgatggatt tgaccagtct gattagtgac ttagagagaa aattagccct
     6361 atcgaaactg gaatctgagc aagtagccct caatcaacag gaagcacaag cccgtttggc
     6421 tactttggag gataagagaa gttcactcag ccaagaaaaa tctgataaag aaagctcttt
     6481 agccctcttg gaagaaaatc tagtccaaaa taatcaaaaa ctcaatcgat tagaggctga
     6541 attgctagct ttttcagatg atcctgatca gatgattgag ctcttacgtg aacgctttgt
     6601 ggccctttta caagaagaag cagatgtctc aaaccaactg acccgtattg agaatgagtt
     6661 ggaaaatagt catcagcttt ctcaaaaaca agcagatcaa ctagaaaagc tgaaagaaca
     6721 gttggctaca gctaaagaga aggctggtca gcaaaaggct gagcttgaaa ctgccaagga
     6781 gcaggttcag aaattattgg ccgactatca agtctgtgct aaggagcaag aggagcagaa
     6841 aacttcctat caagctcaac aaagtcaact ctttgaccgt ctggatagtc tcaaaaacaa
     6901 gcaggctaga gcgcaaagtt tggaaaatat cctgagaaat catagtaact tttatgcagg
     6961 tgttaagagt gttctccaag agaaagatcg tctaggtggg attattggag cagttagtga
     7021 gcacctgacc tttgatatgc attatcaaac tgccctagaa attgcgcttg gagcgagtag
     7081 tcagcacatt attgtagaag atgagaatgc ggcaaccaaa gccattgatt tactcaaacg
     7141 aaacagatct ggtcgtgcaa ccttccttcc tttgaccact atcaaggctc gtacgatttc
     7201 tagtcagaac caagatacta ttgctgcaag tccaggattt ctgggcatgg cagatgagct
     7261 ggttactttc gatactagac tggaagccat tttcaagaat ttgctagcta caacggccat
     7321 ttttgatacc gtggagcatg cgcgtgcagc agcgcgccag gttcgttatc aggttcgtat
     7381 ggtgacattg gacggaacag agctgcgcac aggtggttct tatgcaggtg gagctaatcg
     7441 ccagaataac agtattttca tcaagccaga actggagcaa ttacaaaaag aaattgctga
     7501 agaagaagca agtttgcgtt cagatgaagt gagtttgaag aacttgcaag atgagctagc
     7561 tagattgaca gaaagattag aagccatcaa atctcaggga gagcaggctc gtattcagga
     7621 gcaaggcttg tccctcgcct atcagcagac cagtcagcaa gttgaagagc tagaaactct
     7681 ttggaaactc caagaagagg aattaaatcg tctttctgag ggagaatggc aagcggataa
     7741 ggaaaaatgc caagagcgcc ttactacaat cactagtgaa aagaataatc tggaagctga
     7801 gattgaagag attaagtcta ataaaaacgc catccaagaa cgttatcaaa acttgcagga
     7861 agagctagct caagctcgtc tacttaagac agaactgcaa gggcaaaaac gttatgaagt
     7921 tgctgatatt gaacgcttag gtaaggaact agataatctt gatattgagc aagaagaaat
     7981 tcagcgcctt cttcaagaaa aggttgacaa tcttgagaaa gttgatacgg atttgctcag
     8041 tcaacaggct gatgaagcca aaactcaaaa aacaaatctc caacaaggtt tgattcgcaa
     8101 gcagtttgag ttggatgata ttgagggtca actggatgat attgctagtc atttggatca
     8161 ggctcgccag cagaatgaag agtggattcg caagcaaact cgtgctgaag ccaagaaaga
     8221 aaaggttagc gagcgcttgc gccatctaca aaatcaatta acagaccagt accagattag
     8281 ctatactgaa gcactagaaa aagcgcatga gttggaaaat ctcaatctgg cagagcaaga
     8341 ggtgcaggat ttagagaagg ctattcgctc actgggacct gtcaatttag acgctattga
     8401 acagtacgaa gaagttcaca accgtctgga tttcctaaat agccaacgtg atgatatttt
     8461 gtctgcgaaa aacctgcttc ttgaaaccat cacagagatg aatgatgagg tcaaggaacg
     8521 ctttaaatca acctttgagg ccattcgtga gtcctttaaa gtgaccttca agcagatgtt
     8581 tggtggaggt caggcagact tgatattgac tgagggcgac cttttaacag ctggtgtgga
     8641 gatttctgtt caacctccag gtaagaaaat ccagtcgctt aacctcatga gtggtggtga
     8701 aaaagctcta tcggctcttg ccttgctttt ctccattatt cgtgtcaaga ccattccttt
     8761 tgtcatcttg gatgaggtag aggctgcgct agacgaagcc aatgttaaac gtttcgggga
     8821 ttatctcaac cgctttgata aggacagtca atttattgtc gtaacccacc gtaaggggac
     8881 catggcagcg gccgattcta tctatggagt gaccatgcaa gaatcgggtg tttcaaagat
     8941 tgtttcagtt aagttaaaag atttagaaag tattgaagga tgacaattaa actagtagca
     9001 acggatatgg acggaacctt cctagatggg aatggacgct ttgatatgga tcgtctcaag
     9061 tctctcttgg cttcctacaa ggaaaaaggg atttactttg cggtggcttc gggtcgggga
     9121 tttctgtctc tggaaaaatt atttgctggt gttcgtgatg acattatttt catcgcggaa
     9181 aatggcagtt tggtagagta tcaaggtcag gacttgtatg aagcgactat gtctcgtgac
     9241 ttttatctgg caacttttga aaagctgaaa acgtcacctt atgtagatat caataaactg
     9301 ctcttgacgg gtaagaaggg ttcatatgtt ctagatacgg ttgatgagac ctatttgaaa
     9361 gtgagtcagc attataatga aaatatccaa aaagtagcga gtttggaaga tatcacagat
     9421 gacattttca aatttacaac caacttcaca gaagaaacgc tggaagctgg tgaagcttgg
     9481 gtcaatgata atgtccctgg tgtcaaggct atgacaactg gctttgaatc tattgatatt
     9541 gttctggact atgtcgataa gggtgtagct attgttgaat tagctaaaaa acttggtatc
     9601 acaatggatc aggtcatggc ttttggagac aatcttaatg acttacatat gatgcaggtt
     9661 gtgggacatc ctgtagctcc tgaaaatgca cgacctgaaa ttttagaatt agcaaagact
     9721 gtgattggtc accataagga acggtcggtt atagcttata tggagggctt ataatggcag
     9781 atataaaatt gattgcattg gacttggacg ggaccttgct gactactgat aaaaggctga
     9841 cggatcgtac caaggaaacc ttgaaagctg cgcgtgatcg tggtatcaag gtcgtattga
     9901 caactggtcg tcccttaaaa gccatggatt tctttctcca tgagttaggg actgacggtc
     9961 aggaagatga gtataccatt acttttaatg gtggattagt tcagaaaaat acaggagaaa
    10021 tccttgataa aacagtcttt tcatatgatg atgtggcacg tttgtatgaa gaaacagaga
    10081 aattatcact gcctctcgat gccatctcag aaggaacagt ttatcaaatc caatcggacc
    10141 aagaaagtct ttatgccaaa ttcaatccag ctttgacctt tgttccagtg gactttgaag
    10201 acttatctag tcaaatgacc tacaacaaat gcgtgactgc ctttgctcaa gaacccttgg
    10261 atgcagccat tcagaagatt tctccagaat tgtttgacca atatgaaatc tttaaatcac
    10321 gtgaaatgtt gctagaatgg tcaccaaaga atgttcataa agcaacaggt ttggcaaaac
    10381 taatcagcca tcttggaatc gaccaaagtc aagtgatggc ttgtggtgac gaggccaatg
    10441 acctctctat gattgaatgg gcaggtcttg gtgttgctat gcaaaacgct gttcctgaag
    10501 taaaggcagc cgcaaatgta gtgacgccga tgaccaacga tgaggaagct gtcgcctggg
    10561 ctatcgaaga atatgtgcta aaggagaact aagatatggg attgtttgac cgtctattcg
    10621 gaaaaaaaga agaacctaaa atcgaagaag ttgtaaaaga agctctggaa aatcttgatt
    10681 tgtctgaaga tgttgatcct accttcacag aagttgagga agtttctcag gaagaagcag
    10741 aggttgaaat tgttgaacaa gctgtgttcc aagaagagga aatccaagac acagttgaag
    10801 aaagtctgga tttagagcca gttatagaag tttctcaaaa agaagtcaaa gaatttccac
    10861 actcagaaga agggaatact gagtttctag agactgtaga agaaaataat tctgaaattc
    10921 ttgaagcaga aaggcctcaa acagaagaaa ctgttcagga aaaatatgac cgcagtctta
    10981 agaaaactcg cacaggtttc ggtgcccgct tgaatgcctt ctttgctaac ttccgctctg
    11041 ttgacgaaga atttttcgag gaactggaag aactgttgat tatgagtgat gttggtgtcc
    11101 aagtcgcttc taacttaacg gaggaactac gttacgaagc caagcttgaa aatgccaaga
    11161 aacctgatgc acttcgtcgt gtcatcattg agaaattggt tgagctttat gaaaaggatg
    11221 gtagctacga tgaaagcatc cacttccaag ataacttgac agttatgctc tttgttggtg
    11281 tgaatggtgt tgggaaaaca acttctatcg gaaaactagc tcaccgctac aaacgagctg
    11341 gtaagaaggt catgctggtt gcagcagata ccttccgtgc gggtgcagta gctcagctag
    11401 ctgaatgggg ccgacgagta gatgttccag tagtaactgg acctgaaaaa gctgatccag
    11461 ccagcgtggt ctttgatggt atggaacgtg ccgtggctga aggtatcgat attctcatga
    11521 ttgatactgc tggtcgtctg caaaataagg ataaccttat ggctgagttg gaaaagattg
    11581 gtcgtattat caaacgtgtt gtgccagaag caccacatga aaccttcttg gcacttgatg
    11641 catcaacagg tcaaaatgcc ctagtacagg ccaaagaatt ttcgaaaatc acacctttaa
    11701 cgggaattgt tttgactaag attgatggaa ctgctcgagg aggtgtggtt ctagccattc
    11761 gtgaagaact caatattcct gtaaaattga ttggttttgg tgaaaaaatc gatgatattg
    11821 gagagtttaa ctcagaaaac ttcatgaaag gtctcttgga aggtttaatc taatcagaag
    11881 caaaaatcct gcaaggcata aacttgcagg aaattttttt attctaagcg accatcttga
    11941 cgataggcga tatctggttg ccaagtccat ttggcaccga atttttcaag taggtcaaag
    12001 ctggcttgag gtcccatgct tccagcttta tagtcatgaa gtggggcacc attttcatcc
    12061 cagagctctt caatacggtc aatcaacttc catgatgcac caacttcatc ccagtggcta
    12121 aagttagttg agttgttatt taggacatca taaatcaatt tctcgtatgg ttctggagaa
    12181 gcaccagttg cagtcgcatc tgtacggtaa tcaagtgagt taggagccaa gttaaattct
    12241 tctcctactt gcttcccatt taggctaaga gagaagcctt ctgttggttg aatatagatg
    12301 gtcaaaatat ttggagcaag tggttctcca aagatagaat ccatttgttt aaagacgatg
    12361 ttgacatgag ttcctttttc agtcagtcgt ttacctgtac ggaaaaagaa aggaacacta
    12421 cggaatcgat cgctgtctac aaagaaggca ccagatgtaa aggtttcagt tgttgattct
    12481 ggattcacat ttggctcgct acgataagag atgtatttca tgccatcaat cttaccagag
    12541 cggtattgcc cacggataaa gtgttctttg agttcttcat cagttggatg atagaggttt
    12601 ttaaagacct taatcttttc agcacgaatc tcgtcttttg tgaagcttgc tggtttgtcc
    12661 atggcgagga gcgaaagaag ttgtagagtg tggttttgga ccatgtcacg gagggcaccg
    12721 gattggtcat agtagccacc acgttcttct acacccaagc gctccgcaaa ggtaatttga
    12781 acattgtcga taaaatcctt gttccaaacg ttttcaaaaa tcaagtttgc aaagcgaact
    12841 gcaaagatgc tttggatcat ttccttacca agataatggt cgatacggaa aatttgttct
    12901 tcgtcaaatg ttgctaggag ttcgtcattc aacttgcttg cagttgcgta atctgtacca
    12961 aatggttttt caacgatcaa gcgctcaaaa cctttgccat cgacaatgtt ttcagatttg
    13021 aggtgtttgg caatggttcc aaagaactga ggtgccatag acaagaagaa gagcttattg
    13081 tgttcagctt ggtatttttc attaagctca gcttgtaatt gacgcaaagc aatataatgt
    13141 tccgaatcat tgacatcatg gctttgatag tagaagtggc tagcaaattc ttgggcttgc
    13201 tcggtactat ctgccaaatc aaggatggac tcgacaacta cagattcaaa atattcctta
    13261 ctccaaggtc tacgggcagt tccaataacg gcaaagtgct tggaaagatt gccggattta
    13321 tatagtctaa aaagggaagg gtagagcttg cgtttagcca ggtctccact cgcaccgaaa
    13381 attgtaacaa taaccttaga tgacatctag ctacctaatt tctattttta ttcctagtct
    13441 tgctaggtat gaggaaacct catttcataa acttaattct aacataattt tccgaaaaat
    13501 caaaaattcc aatacgaagt agaaaaactg caaggaaatc cttacagttt gagtttagac
    13561 gtttaagacc ttatctaaga actctttcag acgagggtgt tgtgggttat caaagatttg
    13621 gtcaggtgtt ccgtcttcaa ggaactcgcc atctgcagta aagataacgc ggttggcaac
    13681 ctgacgagca aatcccatct catgggttac gataatcatg gtcatacctt gctcagccaa
    13741 ttccttcata acgttaagta cgtctccaac catctcaggg tcaagggcag aagttggttc
    13801 atcgaagagc atgatgtctg gattcattgc taggccacga gcgatggcca cacgttgttt
    13861 ttgaccacct gataggctat ctggattggc attagcttta tctgctagtc caaccttttc
    13921 aagcaactcc attcccaatt cctcagcttc ttccttagtc atcaacttgt gctcaatagg
    13981 agcaaaggtg atgttgtcca atacagacat atgagggaag aggttgaagt gttggaatac
    14041 catgccgata ttttcacgga cgtggtcaac attggttgtt ttttcagtta aatcatagcc
    14101 gttcacagtg atgtgaccgc tagtgacttc ttctaaaaga ttgaggctac ggaggaaagt
    14161 tgacttacca gaacctgaag gaccgatgat acaaacaaca tctccttcat agaacttagt
    14221 cgtaattcct tttaggactt cattttttcc atagtgcttg tgtaaatcat ttacatcaat
    14281 ttttaatttt gccattaacg aatcctcttt tctaagcgtt tcgctagtct agtcaaaagt
    14341 gtgataatta caagatagaa gatagcaagg attgcataca tcttgaaact ttggtagtta
    14401 cgagcaatga taatcttacc agtttggaag agttcaacca aaccgatagc agatacgata
    14461 gttgtatctt taagagcgat aacgaattgg ttgacaaagt ttggcaacat caatttagtt
    14521 gcttgtggca agataatctt acgcatggtt tttccataag agatacccaa gcttcggctg
    14581 gcttccattt ggccaactgg aacggcctga ataccaccac gaacgatttc agcgatataa
    14641 gcagccgcat tgagtgagag ggcaatggtt ccagctacaa agtcgttaat tgggctttgt
    14701 tggcctgtga tagactcgat gaagtttgga attccccaga agatgaaggc tgcaagaatc
    14761 atcaatggaa taccacgaat aacgtcaacg aaaatctcag agatgacgcg aagagatttg
    14821 tatgggctaa cgctaaacat accgaagata attccgatga caatggcaat agcaaatgag
    14881 ataagagcta gagcaagagt gataccaaga ccgctaagga gttgtttgta gttgttttga
    14941 agcaagcccc agagcgttgt ttcgtcaaca gtacttgttg aagcagttga agattcgcta
    15001 gctaggtatt tgtcaagaat cttttggaat tcaccgtttg ctttaaggtt tgcaagtccg
    15061 ttgttgaaca tttcaatcag ttctggattt gctccttttt taacggcaaa ggctgtttca
    15121 ccgattggag ttccagagat tggagttttc aatttttgac cttggctgat agaatatttg
    15181 agaacaggtt catcatccat aacggcatca atggcaccag tgtttaaact gtcatacatt
    15241 gaagaaccat cagcaaaggt tttgattttg taaccgtatt tgctttgatt ttctgttagg
    15301 aaggtttgag aagcagttcc gtttttaaca ccgactgtct ttccttttag atcttcataa
    15361 gaagcaatat tgcttgattc tttgacacca agaatggtat tagcagtgta gtatgattct
    15421 gagaagtcaa aagttgcctt acgagcatct gtgacagaca tcccagcaat gataccatcg
    15481 gcttgaccag cttggacagc actgatagca gcatcaaaac cagggttggt gatttcaatt
    15541 tcaaaacctt ggtctttagc gattgcctta atcaattcca tatcaatacc agtgtattgg
    15601 ttgcttgaat tttggaaaac aaaaggtgca aaagaagaat cgctggcaat gatatattta
    15661 gccttaacag gaatagcttt taatcctgcg agagtagttg tagttggcac tgctgaagat
    15721 gatgaagcag tccatttctt gataatttta tcaagactac catctttttt catttcagcc
    15781 aaggcttggt taaattcagt aaccaggtgc tcgtatttac ttcctttttt cacaccgaaa
    15841 gcaaaacttc ctacagcttc accatccatt tcaatatgga gatcttgacc ttggttaatg
    15901 gcatattcga taacaggttt gtcatccatc atggcatcga tggcaccagc actcaagctg
    15961 ttgttcatta aatcaccagt gtcaaatgtt ttaatagtaa agccgtattt atctttgatt
    16021 gtttcaagga aacgttgagc ggcagttccg tttttaacac caacggtttt gccagttaat
    16081 tggtcgtact tgctaatttt gtgtgacttt gtagtagcaa tgacaacttt tgtatcatag
    16141 taagtatcag acatggtgaa gactttttca cgttctttag tctttgtcat ccctgccatg
    16201 atagcgtcgg cttgcccagc ttgaaccgca ttgactgctg cgtcaaatcc aggataggac
    16261 atctgaatgt tccagccttt aatctcagcg actttgttaa taatgtcaac atcaattcct
    16321 ttataagttt gatctgaatc tttaaactca aaaggtgcat aggcggtatc agaaacaatc
    16381 ttaatcgttt ctgctttggc aatacctaat gagaaaattg ggaataaaat tagcaaaaat
    16441 gctagaaatt ttttcttcat ttttagtctc cttttccgaa tattctctca ttatatcaga
    16501 aaaagtaaaa aaaggcaaat tgttatattt ttc
//
LOCUS       DAVLAQ010000039        16447 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000039 DAVLAQ010000000
VERSION     DAVLAQ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.039"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..913
                     /gene="lytB"
                     /locus_tag="VXB71_001403"
     CDS             <1..913
                     /gene="lytB"
                     /locus_tag="VXB71_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0451505.1"
                     /translation="GGYMAKNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTANVY
                     DSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYY
                     ESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEAT
                     NYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIA
                     KDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNV
                     EYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(974..2629)
                     /gene="pavA"
                     /locus_tag="VXB71_001404"
     CDS             complement(974..2629)
                     /gene="pavA"
                     /locus_tag="VXB71_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0451506.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIGLDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2734..3231
                     /gene="ybeY"
                     /locus_tag="VXB71_001405"
     CDS             2734..3231
                     /gene="ybeY"
                     /locus_tag="VXB71_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0451507.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHKLNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3212..3607
                     /locus_tag="VXB71_001406"
     CDS             3212..3607
                     /locus_tag="VXB71_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0451508.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3624..4523
                     /gene="era"
                     /locus_tag="VXB71_001407"
     CDS             3624..4523
                     /gene="era"
                     /locus_tag="VXB71_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0451509.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4572..5396
                     /gene="mutM"
                     /locus_tag="VXB71_001408"
     CDS             4572..5396
                     /gene="mutM"
                     /locus_tag="VXB71_001408"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0451510.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5396..6001
                     /locus_tag="VXB71_001409"
     CDS             5396..6001
                     /locus_tag="VXB71_001409"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0451511.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5988..7187
                     /locus_tag="VXB71_001410"
     CDS             5988..7187
                     /locus_tag="VXB71_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEV0451512.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7187..7336
                     /gene="rpmG"
                     /locus_tag="VXB71_001411"
     CDS             7187..7336
                     /gene="rpmG"
                     /locus_tag="VXB71_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0451513.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7376..7609
                     /gene="secG"
                     /locus_tag="VXB71_001412"
     CDS             7376..7609
                     /gene="secG"
                     /locus_tag="VXB71_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0451514.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7711..10065
                     /gene="rnr"
                     /locus_tag="VXB71_001413"
     CDS             7711..10065
                     /gene="rnr"
                     /locus_tag="VXB71_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0451515.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNH
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYVDVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10028..10495
                     /gene="smpB"
                     /locus_tag="VXB71_001414"
     CDS             10028..10495
                     /gene="smpB"
                     /locus_tag="VXB71_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0451516.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10511..11371
                     /gene="tehB"
                     /locus_tag="VXB71_001415"
     CDS             10511..11371
                     /gene="tehB"
                     /locus_tag="VXB71_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0451517.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11444..12397
                     /gene="coiA"
                     /locus_tag="VXB71_001416"
     CDS             11444..12397
                     /gene="coiA"
                     /locus_tag="VXB71_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0451518.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12416..14218
                     /gene="pepF"
                     /locus_tag="VXB71_001417"
     CDS             12416..14218
                     /gene="pepF"
                     /locus_tag="VXB71_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0451519.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14220..14933
                     /locus_tag="VXB71_001418"
     CDS             14220..14933
                     /locus_tag="VXB71_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0451520.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15000..15941
                     /gene="prsA"
                     /locus_tag="VXB71_001419"
     CDS             15000..15941
                     /gene="prsA"
                     /locus_tag="VXB71_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0451521.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16058..16399)
                     /locus_tag="VXB71_001420"
                     /pseudo
     CDS             complement(16058..16399)
                     /locus_tag="VXB71_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4947 a         3080 c         3678 g         4742 t
ORIGIN      
        1 tggtggctac atggcgaaaa atgagacagt agatggttat cagcttggaa gcgatggtaa
       61 atggcttgga ggaaaaacta caaatgaaaa tgctgcttac tatcaagtag tgcctgttac
      121 agccaatgtt tatgattcag atggtgaaaa gctttcctat atatcgcaag gtagtgtcgt
      181 atggctagat aaggatagaa aaagtgatga caagcgcttg gctattacta tttctggttt
      241 gtcaggctat atgaaaacag aagatttaca agcgctagat gctagtaagg actttatccc
      301 ttattatgag agtgatggcc accgttttta tcactatgtg gctcagaatg ctagtatccc
      361 agtagcttct catctttctg atatggaagt aggcaagaaa tattattcgg cagatggcct
      421 gcattttgat ggttttaagc ttgagaatcc cttccttttc aaagatttaa cagaggctac
      481 aaactacagt gctgaagaat tggataaggt atttagtttg ctaaacatta acaatagcct
      541 tttggagaac aagggcgcta cttttaagga agccgaagaa cattaccata tcaatgccct
      601 ttatctcctt gcccatagtg ccctagaaag taactgggga agaagtaaaa ttgccaaaga
      661 taagaataat ttctttggca ttacagccta tgatacgacc ccttaccttt ctgctaagac
      721 atttgatgat gtggataagg gaattttagg tgcaaccaag tggattaagg aaaattatat
      781 cgatagggga agaactttcc ttggaaacaa ggcttctggt atgaatgtgg aatatgcttc
      841 agacccttat tggggcgaaa aaattgctag tgtgatgatg aaaatcaatg agaagctagg
      901 tggcaaagat tagtactata agtgaatatg atttgagtga atagtaagtt aaaaatcctg
      961 atttcaagta aaatcaggat tttttcatgg atgcaatttt tttggagtct ggtgtgacgc
     1021 ggagggtctt ttgtcctgtg taagtgacaa agccgggttt tccaccagtt ggtttattga
     1081 gttttttgac ttcaatcata tctacctgca ccagattcga caggcgccct tgagagaagt
     1141 aggcagctaa ctctgctgcg tctgtcttga ctgcatcaga tgggtcaaga tttcctgaga
     1201 tgacaacatg gcttccagga atgtccttag catggaacca aagttcctcc ttgcgggcca
     1261 ttttaaaggt caattcctca ttttgaagat tgtttcgtcc gacatagatg atggttttgc
     1321 catcgcttgc tagatattgt tctagttttt tgcgtttctg gattttctcc cgttgtcttc
     1381 tgcggataaa acctgtttga atcaattctt cacggatttc agcgatttct tccagtccag
     1441 cttggttgag gacggtttct acactttcca gatagagaat agtggctttg gtttcttcaa
     1501 tcaaatcagt caagtatttg acagcttctt tgagtttctg ataccgttta aaatagcgtt
     1561 gggcattctg gttgggagtc agagccttat caagcccaat catgataggt tggttggtat
     1621 agtagttgtc taggataacc tggtcttggt cgttaggcac ttggtggagg aaggttgtca
     1681 gcaattctcc tttttgacga aattcttcag cgttgtctgt cgccagtaat tctttttcct
     1741 gttttttgag tttgtgtcgg tttttctgaa gttcattttc aacacgacga atcagttcac
     1801 tggcctgctg tttgacgcgg tcgcgctcag ccttatcctt atagtaggtg tccaacaaat
     1861 cagaaagatt tgcaaaaggc tctcccacct gatttgcaaa aggaactgga ctgaaggaag
     1921 tctcagtcaa gcatggcttg gtttcctgat tgaaaaaatt tcggaaagcg gaaagttttt
     1981 cactaaccag tatcctttcc aattcatttg ccgtatcgcg tcccagacct tgaaagaggc
     2041 tttgaagatt ttttgctgtt agttcttggg tttgcaggat ttcaaagagc ttttcatcct
     2101 tgatagtaaa aggattgaga gattctgtac ttggcggagc gatataggtc gatcctggaa
     2161 gtaaggtgcg gtagctattt tgtgaaaagc cgacgtgttt gataacttcg aggattttat
     2221 gactgctttt atcgaccagt agaatattac tgtgtttccc cataatttcg ataatcaagg
     2281 tagcctggat atggtctcca atctcgtttt tattggaaac tgtcatttcc acaatacggt
     2341 cattttccac ttgctcaatc gactcaatca gggccccctg caaatacttt ctcaaaacca
     2401 tgataaaggt agaaggttgg gctggatttt caaaagtcgt ttgggtcagc tgaatgcgtc
     2461 caaaaactgg atgggcagaa aggagcaggc gatggctttg gcgattgctg cggatttgca
     2521 agaccaactc ttgttcaaaa ggctgattga ttttctggat gcgaccattc actaattcgc
     2581 ttcgcaattc ctcaactatg tggtgtaaaa aaaatccgtc aaatgacatc gttctctcct
     2641 tgtgattgta ttccatagta ttatatcaaa aaggtagaat aaaatcatgg aaatgtggta
     2701 taataaagcc aagtaaagag aaacgagaag cacatgtata ttgaaatggt agatgaaact
     2761 ggtcaagttt caaaagaaat gttgcaacaa acccaagaaa ttttggaatt tgcagccaaa
     2821 aaattaggaa aagaagacaa ggagatggca gtcacttttg tgaccaatga gcgtagtcat
     2881 aaacttaatc tggagtaccg tgacaccgac cgtccgacag atgtcatcag ccttgagtat
     2941 aaaccagaat tggaaattgc ctttgacgaa gaggatttgc ttgaaaatcc agaattggca
     3001 gagatgatgt ctgagtttga tgcctatatt ggggaattgt tcatctctat cgataaggct
     3061 catgagcagg ccgaagaata tggtcacagc tttgagcgtg agatgggctt cttggcagta
     3121 cacggctttt tacatattaa cggctatgat cactatactc cggaagaaga agcggagatg
     3181 ttcggtttac aagaagaaat tttgacagcc tatggactca caagacaata aacgaaaatg
     3241 gaaaaatcgt gacctgatat ccagtttaga atttgccatc acagggattt ttactgctat
     3301 caaggaagaa cgcaatatgc gaaaacatgc agtgacggct ctagtggtca tccttgcagg
     3361 ttttggtttt caggtgtcac gaatcgaatg gctctttctc ctattgagca ttttcttggt
     3421 ggtagccttt gaaattatca attctgctat tgaaaatgtg gtggatttgg ccagtcacta
     3481 tcacttttcc atgctggcta aaaatgccaa ggatatggcg gctggcgcgg tattagtggt
     3541 ttctcttttt gcagccttaa caggcgcatt gatttttctc ccacgaatct gggatttatt
     3601 attttaaaca gtaagaggaa attatgactt ttaaatcagg ctttgtagcc attttaggac
     3661 gtcccaatgt tgggaagtca acctttttaa atcacgttat ggggcaaaag attgccatca
     3721 tgagtgacaa ggcgcagaca acgcgcaata aaatcatggg aatttacacg actgataagg
     3781 agcaaattgt ctttatcgac acaccaggga ttcacaaacc taaaacagct ctcggagatt
     3841 tcatggttga gtctgcctac agtacccttc gcgaagtgga cactgttctt ttcatggtgc
     3901 ctgctgatga agcgcgtggt aagggggacg atatgattat cgagcgtctc aaggctgcca
     3961 aggttcctgt gattttggtg gtgaataaaa tcgataaggt ccatccagac cagctcttgt
     4021 ctcagattga tgacttccgt aatcaaatgg actttaagga aattgttcca atctcagccc
     4081 ttcagggaaa taacgtgtct cgtctagtgg atattttgag tgaaaatctg gatgaaggtt
     4141 tccaatattt cccgtctgat caaatcacag accatccaga acgtttcttg gtttcagaaa
     4201 tggttcgcga gaaagtcttg cacttaactc gtgaagagat tccgcattct gtagcagtag
     4261 ttgttgactc tatgaaacga gacgaagaga cagacaaggt tcacatccgt gcaaccatca
     4321 tggtcgagcg cgatagccaa aaagggatta tcatcggtaa aggtggcgct atgcttaaga
     4381 aaatcggtag catggcccgt cgtgatatcg aactcatgct aggagacaag gtcttcctag
     4441 aaacctgggt caaggtcaag aaaaactggc gcgataaaaa gctagatttg gctgactttg
     4501 gctataatga aagagaatac taagtagagg taggctcatg cctgcttctt gtttttacag
     4561 aaggaggact tatgcctgaa ttacctgagg ttgaaaccgt ttgtcgtggc ttagaaaaat
     4621 tgattatagg aaagaagatt tcgagtatag aaattcgcta ccccaagatg attaagacgg
     4681 atttggaaga gtttcaaagg gaattgccta gtcagattat cgagtcaatg ggacgtcgtg
     4741 gaaaatattt gcttttttat ctgacagaca aggtcttgat ttcccatttg cggatggagg
     4801 gcaagtattt ttactatcca gaccaaggac ctgaacgcaa gcatgcccat gttttctttc
     4861 attttgaaga tggtggcacg cttgtttatg aggatgttcg caagtttgga accatggaac
     4921 tcttggtgcc tgacctttta gacgcctact ttatttctaa aaaattaggt cctgaaccaa
     4981 gcgaacaaga ctttgattta caggtctttc aatctgccct tgccaagtcc aaaaagccta
     5041 tcaaatccca tctcctagac cagaccttgg tagctggact tggcaatatc tatgtggatg
     5101 aggttctctg gcgagctcag gttcatccag ctagaccttc ccagactttg acagcagaag
     5161 aagcgactgc cattcatgac cagaccattg ctgttttggg ccaggctgtt gaaaaaggtg
     5221 gctccaccat tcggacttat accaatgcct ttggggaaga tggaagcatg caggactttc
     5281 atcaggtcta tgataagact ggtcaagaat gtgtacgctg tggtaccatc attgagaaaa
     5341 ttcaactagg tggacgtgga acccactttt gtccaaactg tcaaaggagg gactgatggg
     5401 aaaaatcatc ggaatcactg ggggaattgc ctcaggtaag tcaactgtga caaattttct
     5461 aagacagcaa ggctttcaag cagtggatgc cgacgcagtc gtccaccaac tacagaaacc
     5521 tggtggtcgt ctgtttgagg ctctagtaca gcactttggg caagaaatca ttcttgaaaa
     5581 cggagaactc aatcgccctc tcctagctag tctcatcttt tcaaatcctg aagagcaaaa
     5641 atggtctaat caaattcaag gggagattat ccgtgaggaa ctggctactt tgagagaaca
     5701 gttggctcag acagaagaga ttttcttcat ggatattccc ctactttttg agcaggacta
     5761 cagcgattgg tttgctgaga cttggttggt ctatgtggac cgagatgccc aagtagaacg
     5821 cttaatgaaa agggaccagt tgtccaaaga tgaagctgag tctcgtctgg cagcccagtg
     5881 gcctttagaa aaaaagaaag atttggccag ccaggttctt gataataatg gcaatcagaa
     5941 ccagcttctt aatcaagtgc atatccttct tgagggaggt aggcaagatg acagagatta
     6001 actggaagga taatctgcgt attgcctggt ttggtaattt tctgacagga gccagtattt
     6061 ctttggttgt accttttatg cccatcttcg tggaaaatct aggtgtaggg agtcagcaag
     6121 tcgcttttta tgcaggctta gcaatttctg tctctgctat ttccgcggcg ctcttttctc
     6181 ctatttgggg tattcttgct gacaaatacg gccgaaaacc catgatgatt cgggcaggtc
     6241 ttgctatgac tatcactatg ggaggcttgg cctttgtccc aaatatctat tggttaatct
     6301 ttcttcgttt actaaacggt gtatttgcag gttttgttcc taatgcaacg gcactgatag
     6361 ccagtcaggt tccaaaggag aaatcaggct ctgccttagg tactttgtct acaggcgtag
     6421 ttgcaggtac tctaactggt ccctttattg gtggctttat tgcagaatta tttggcattc
     6481 gtacagtttt cttactggtt ggtagttttc tatttttagc tgctattttg actatttgct
     6541 ttatcaagga agattttcaa ccagtagcca aggaaaaggc tattccaaca aaggaattat
     6601 ttacctcggt taaatatccc tatcttttgc tcaatctctt tttaaccagt tttgtcatcc
     6661 aattttcagc tcaatcgatc ggccctattt tggctcttta tgtacgcgac ttagggcaga
     6721 cagagaatct tctttttgtc tctggtttga ttgtgtccag tatgggcttt tccagtatga
     6781 tgagtgcagg agtcatgggc aagctaggtg acaaggtggg caatcatcgt ctcttggttg
     6841 tcgcccagtt ttattcagtc atcatctatc tcctctgtgc caatgcctct agcccccttc
     6901 aactaggact ctatcgtttc ctctttggct tgggaaccgg tgccttgatt cccggggtta
     6961 atgccctact cagcaaaatg actcccaaag ccggcatttc gagggtcttt gcctttaatc
     7021 aggtattctt ttatctggga ggtgttgttg gtcccatggc aggttctgca gtagcaggtc
     7081 aatttggcta ccatgctgtc ttttatgcga caagcctttg tgttgccttt agttgtctct
     7141 ttaacctgat tcaatttcga acattattaa aagtaaagga aatctagtgc gagtaaaaat
     7201 taatctcaaa tgctcctctt gtgacagtat caattaccta accagtaaaa attcaaaaac
     7261 ccatccagac aagattgagg ttttaaagta ttgtcccaag gaaagaaaag taaccctaca
     7321 tcttgaatct aagtagattt tatggtaaaa taatagggat tttaaggagt ttgatatgta
     7381 taacctatta ttaaccattt tattagtatt atctgttgtg attgtgattg caattttcat
     7441 gcaaccaacc aaaaaccaat ccagcaatgt atttgatgcc agttcaggtg atttgtttga
     7501 acgcagtaaa gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga ttttagtctt
     7561 tttctggcta gccattgcct tagcattgac ggtattatca agtagataag aaaataatgg
     7621 gcaggactag gtctttgcct ctttttattt ttaaaggatg tttgagaagg ttttacagta
     7681 aaagaaaatt aaaaaatcta gaaagaaaat atgaaagata gaataaaaga atatttacaa
     7741 gacaagggaa aggtgactgt taatgatttg gctcaggctt tgggaaaaga cagttccaag
     7801 gattttcgtg agttgattaa aaccttgtcc ttaatggaaa gaaagcacca gattcgcttt
     7861 gaagaagatg gtagtctgac attagaaatt aagaaaaaac atgagattac cctcaagggg
     7921 atttttcatg cccataaaaa tggctttggc tttgttagtc tggaaggcga ggaggacgac
     7981 ctttttgtag ggaaaaatga tgtcaactat gctattgatg gtgataccgt cgaggtagtg
     8041 attaagaaag tcgctgaccg caataaggga acagcagcag aagccaaaat tattgatatc
     8101 ctagaacaca gtttgacaac agttgtcggg caaatcgttc tggatcagga aaagcctaag
     8161 tatgctggct atattcgttc aaaaaatcat aaaatcagtc aaccgattta tgttaagaaa
     8221 ccagccctaa aattagaagg aacagaagtt ctcaaagtct ttatcgataa atacccaagc
     8281 aagaaacatg atttctttgt cgctagtgta ctcgatgtag tgggacactc aacggatgtc
     8341 ggaattgatg ttcttgaggt cttggaatca atggacattg tatctgagtt tccagaagct
     8401 gttgtcaagg aagcagaaag tgtgcctgat gctccgtctc aaaaggatat ggaaggtcgt
     8461 ctggatctaa gagatgaaat tacctttacc attgacggtg cggatgccaa ggacttagac
     8521 gatgcagtgc atatcaaggc tctgaaaaat ggcaatctgg agcttggggt tcacatcgca
     8581 gatgtttcct attatgtgac cgaggggtct gcccttgaca aggaagccct taaccgtgcg
     8641 acttctgttt acgtgacaga ccgagtggtg ccaatgcttc cagaacgact atcaaatggc
     8701 atctgctctc tcaatcccca agttgaccgc ctgacccagt ctgctattat ggagattgat
     8761 aaacatggtc gtgtggtcaa ctataccatt acacaaacag ttatcaagac cagttttcgt
     8821 atgacctata gcgatgtcaa tgatatccta gctggcgatg aagaaaagag aaaagaatat
     8881 cataaaattg taccaagtat cgaactcatg gccaagcttc atgaaacttt agaaaacatg
     8941 cgtgtgaaac gtggagctct caattttgat accaatgaag cgaagatttt agtggataaa
     9001 caaggtaagc ctgttgatat cgttcttcgg cagcgtggca ttgccgagcg gatgattgag
     9061 tcttttatgt tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt ggatttgcct
     9121 tttatctatc gaattcacga ggagcctaag gctgaaaagg ttcagaagtt tattgattat
     9181 gcttcgagtt ttggcttgcg catttatggg actgccagtg agattagtca ggaggcactt
     9241 caagacatca tgcgtgctgt tgagggagaa ccttatgtag atgtattgtc catgatgctt
     9301 cttcgctcta tgcagcaggc tcgttattcg gagcacaatc acggccacta tggactagct
     9361 gctgactatt atactcactt taccagtcca attcgtcgtt atccagacct tcttgttcac
     9421 cgtatgattc gggattacgg ctgttctaag gaaatagcag agcattttga acaagtgatt
     9481 ccagagattg cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc tgagcgtgaa
     9541 gtcgaagcca tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga gtatgatgca
     9601 gttgtatcaa gtattgtcaa attcggtctc tttgtcgaat tgccaaacac agttgaaggc
     9661 ttgattcaca tcactaatct acctgaattt tatcatttca atgagcgtga tttgactctt
     9721 cgtggagaaa aatcaggtat cactttccga gtgggtcagc agatccgtat ccgtgttgaa
     9781 agagcggata aaatgactgg agagattgat ttttcattcg tacctagtga gtttgatgtg
     9841 attgaaaaag gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc aaatcgtcgt
     9901 tcggataaga aggaagacaa gagaaaatca ggacgctcaa atgataagcg taagcattca
     9961 caaaaagaca agaagaaaaa aggaaagaaa cctttttaca aggaagtagc taagaaagga
    10021 gccaagcatg gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg cacgccacga
    10081 ctatacaatc gtagatacgc tagaggcagg gatggtcctg actggaactg aaatcaagag
    10141 tgtacgagct gctcgaatta atctcaagga tggctttgct caagtgaaaa atggagaagt
    10201 ttggctgagc aatgttcata tcgcgcctta cgaagagggc aatatctgga accaggaacc
    10261 agaacgtcgt cgtaaactcc tgctccataa aaagcaaatt caaaaattgg aacaagagac
    10321 caaagggaca ggaatgacct tagttcccct taaggtctat ataaaagatg gctacgctaa
    10381 gcttctttta ggacttgcca aagggaagca tgactatgac aaacgggagt ctatcaaacg
    10441 tcgtgagcaa aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc gataaaaaga
    10501 ggaattgaaa atggaaaaat tagttgccta taaacgcatg cctttgtgga ataaacaaac
    10561 aatgcctgaa gctgttcagc aaaagcacaa tacaaaagtt gggacttggg ggaaaattac
    10621 tgtcttgaag ggagctctca agtttattga attgacagaa gaaggggaag ttctagctga
    10681 acacctcttt gaagcagggg cagacaatcc aatggcccaa cctcaagcct ggcaccgagt
    10741 ggaagctgcc acagatgatg tggaatggta cttggaattt tattgtaaac ctgaggatta
    10801 ttttgctaaa aaatacaata ccaatcctgt tcattcagag gtcctagagg ccatgcagac
    10861 agtgaaacaa gggaaagctt tggatttggg ttgtggtcag gggcgtaatt ctctttttct
    10921 agcccagcaa gattttgatg tgacggctgt agatcaaaat ggactagctc ttgaaatctt
    10981 gcaaagcatt gtggagcagg aagatttgga catgcctgtt ggcctttacg atatcaattc
    11041 agctagcatt gaacaagaat atgattttat cgtttcaaca gttgttctca tgtttctaca
    11101 agcggaccgc attccagcta ttattcaaaa tatgcaggag aaaaccagtg ttggcggtta
    11161 caaccttatc gtttgtgcca tggacacgga ggattatcct tgctcggtta acttcccatt
    11221 cacctttaaa gaaggagaac tggcagacta ttacaaggat tgggaattgg ttaagtacaa
    11281 tgaaaatcca ggccatttgc accgtcgcga tgagaatggc aatcgtattc aactacgctt
    11341 tgcgacctta ctagctaaga aaatcaagta aacacacatg aagattagga attttcctga
    11401 tcttttttct tttttacgaa tgatatagaa aaggagggaa ttcatgtttg ttgcgagaga
    11461 tgctagggga gaattggtaa atgtgttaga ggataaactt gagaagcaag catacacctg
    11521 cccagcttgt ggaggccagc tccatttgcg tcaaggacca agtgtacgga cgcattttgc
    11581 ccataaatcc ttaaaagact gtgatttttt ctttgaaaat gaaagtccag aacacctggc
    11641 caataaggaa tccctctatc actggttgaa aaaagagaca aaggttcaat tagagtaccc
    11701 gctttcagaa cttaaacaga ttgcggatgt atttgtaaat ggcaatctag ctctagaagt
    11761 tcagtgtagt cccttgcctc agaaagtcct taaagagcga agtgagggct atcgtagtca
    11821 gggttaccaa gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc gtttgactcg
    11881 tctacagcaa ggttttcttt atttcagtca aaacatgggc ttttatgttt gggaattaga
    11941 caaggaaaaa caagttttaa gactcaaata cctgatttac caggatctcc gcggtaaact
    12001 ccattatcaa atcaaggaat tttcctatgg tcaaggtagt ttattggaaa tattgcgtct
    12061 tccctataag agacaaaaaa tatctcattt tacagtttct gaggacaagg acatctgtcg
    12121 ctatatccgg caacaacttt attatcaaaa tctcttttgg atgaaagaac aagcagaagc
    12181 ctatcaaaag ggagaaaata tcctgactta tggactgaaa gaatggtatc cacaaattcg
    12241 accaatagtg ggcaaatttt tccagattga acaagacttg actagctatt atcagcactt
    12301 ttatacctat taccaaaaaa atcctcaaaa tgattggcaa aagctttatc caccagcctt
    12361 ttatcagcaa tatttcttga aaaatatggt agaatagaaa ggatggagga atctaatggt
    12421 attacaaaga aatgaaataa atgaaaaaga tacatgggat ctatcaacga tctacccaac
    12481 tgaccaggct tgggaagaag ccttaaaaga tttaacagaa caattggaga cagtagccca
    12541 gtatgaaggc catctcttgg atagtgcgga taacctacta gaaatcactg aattttctct
    12601 tgaaatggaa cgccagatag agaagcttta cgtttatgct catatgaaga atgaccagga
    12661 tacacgtgaa gctaagtatc aagagtacta tgccaaggcc atgacactct acagccagtt
    12721 agaccaagcc ttttcattct atgagcctga atttatggag attagcgaaa agcagtatgc
    12781 tgacttttta gaagctcaac caaagctgca ggtttatcaa cactattttg acaagctctt
    12841 gcaaggcaag gatcacgttc tttcacaacg tgaagaagaa ttattggctg gagctggaga
    12901 aatctttggt tcagcaagtg aaaccttcgc tatcttggac aatgcggata ttgtgttccc
    12961 ttatgtccta gacgatgatg gtaaagaagt tcagctatct catgggactt acacacgttt
    13021 gatggagtct aaaaaacgtg aggttcgccg tggtgcctat caagctcttt atgctactta
    13081 cgaacaattc caacacacct atgccaaaac cttgcaaacc aatgttaagg tgcaaaatta
    13141 ccgtgctaaa gttcgtaact acaagagtgc tcgtcatgca gccctcgcag cgaattttgt
    13201 tccagaaagt gtttatgaca atttggtagc agcagttcgc aagcatttgc cactcttaca
    13261 tcgctatctt gagcttcgtt caaaaatctt ggggatttca gatctcaaga tgtacgatgt
    13321 ctacacaccg ctttcatctg ttgaatacag ttttacctac caagaagcct tgaaaaaagc
    13381 agaagatgct ttggcagtct tgggtgagga ttacttgagc cgtgttaaac gtgccttcag
    13441 cgagcgttgg attgatgttt acgaaaatca aggcaagcgt tcaggtgcct actctggtgg
    13501 ttcttacgat accaatgcct ttatgcttct caactggcag gacaatctgg acaatctctt
    13561 tactcttgtt catgaaacag gtcacagtat gcattcaagc tatactcgtg aaactcagcc
    13621 ttatgtttac ggggattact ctatcttttt ggctgagatt gcctcaacta ccaatgaaaa
    13681 tatcttgacg gagaaattat tggaagaagt ggaagacgac gcaacacgct ttgctattct
    13741 caataacttc ctagatggtt tccgtggaac agttttccgc caaactcaat ttgctgagtt
    13801 tgaacacgcc attcaccaag cagatcaaaa tggggaggtc ttgacaagcg atttcctaaa
    13861 taaactctac gcagacttga accaagagta ttatggtttg agtaaggaag acaatcctga
    13921 aatccaatac gagtgggctc gcattccaca cttctactat aactactatg tatatcaata
    13981 ttcaactggc tttgcggccg cctcagcctt ggctgaaaaa attgtccatg gtagtcaaga
    14041 agaccgtgac cgctatatcg actacctcaa ggcaggtaag tcggactatc cacttaatgt
    14101 catgagaaaa gctggtgttg atatggagaa ggaagactac ctcaacgatg cctttgcagt
    14161 ctttgaacgc cgtttaaatg agtttgaagc ccttgttgaa aaattaggat tggcataaaa
    14221 tggttgaatc gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc gtcaaagaag
    14281 aaattgtaga cttgatgcgt cagcgtcaaa agcaggtcac aggtttcttg aaagaattgg
    14341 aagactttgc ccgcaaggaa aatattccta ttattcccca tgaaacggtt gcttatttcc
    14401 gttttcttat ggaaaccatg cagcctaaaa atattctgga aattgggacg gctatcggtt
    14461 tttcagctct cttgatggct gaacatgcgc caaatgctaa gattacaact attgatcgta
    14521 atccagaaat gattggtttt gccaaggaaa attttgccca gtttgacagt cgcaagcaaa
    14581 tcactctcct agagggagat gcggtggatg tcttatctac actgacagag tcttatgatt
    14641 tcgtatttat ggattctgcc aagtctaaat acatcgtctt tctgccagaa atcctcaaac
    14701 atttggaagt tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt gatgttgcca
    14761 aggatattat ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt caaaaattat
    14821 ttgatgcaac cttagacaat ccagaactca ccgcaacatt agtgccttta ggagatggta
    14881 ttctcatgct tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa tgattttcag
    14941 aaaaatttaa gaaaaaatag taaaatagat agagtaacac ttatctcaaa ggagtagaca
    15001 tgaagaaaaa attattggca ggtgccatca cactattatc agtagcaact ttagcagctt
    15061 gttcgaaagg gtcagaagga gcagacctta tcagcatgaa aggggatgtc atcacagaac
    15121 atcaatttta tgagcaagtg aaaaacaacc cttcagccca acaagtcttg ttaaatatga
    15181 ccatccaaaa agtttttgaa aaacaatatg gctcagagct tgatgataaa gaggttgatg
    15241 atactattgc cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc ttgtcacaag
    15301 caggtatgac tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta gttgagttgg
    15361 cagttaagaa ggtagcagaa gctgaattga cagatgaagc ctataagaaa gcctttgatg
    15421 agtacactcc agatgtaacg gctcaaatca tccgtcttaa taatgaagat aaggccaaag
    15481 aagttctcga aaaagccaag gcagaaggtg ctgattttgc tcaattagcc aaagataatt
    15541 caactgatga aaaaacaaaa gaaaatggtg gagaaattac ctttgattct gcttcaacag
    15601 aagtacctga gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt gtttctgatg
    15661 tgattacagc aactggcaca caagcctaca gtagccaata ttacattgta aaactcacta
    15721 agaaaacaga aaaatcatct aatattgatg actacaaaga aaaattaaaa actgttatct
    15781 tgactcaaaa acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa gaattgcaag
    15841 cagccaatat caaggttaag gaccaagcct tccaaaatat ctttacccaa tatatcggtg
    15901 gtggagattc aagctcaagc agtagtacat caaacgaata gtccaaatca atgagtcagg
    15961 gaaaaaactc tacttcagga aaaaatgaag caaacattcc cacaataaaa cgcgtagtac
    16021 aaggtttgta ctgaccccca aaagttagac aaataattta tccgaaggat ttagttctgt
    16081 attgcacagg gctaagtcct tttagtttta ccttaattct cttgttgttg taataatcaa
    16141 tatagtatat aatggcttgt tccaattgat taagtgattt aaatgttttc tcatagccat
    16201 aaaacatttc ggattttaaa ataccaaaga aagattccat cctaccgttg tcttggctgt
    16261 ttcccttgcg tgacatagat gcttgaattc ccttactctc taggaaccga tgataagaat
    16321 cgtgttggta ttgccagtct tggtcactat ggagaatcgt attctcgtag tgcttctctt
    16381 tgaatgcctg ttccaacatt aacgatcaat caatttaatc atgtacctaa tattagaatt
    16441 gtttatc
//
LOCUS       DAVLAQ010000040        15753 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000040 DAVLAQ010000000
VERSION     DAVLAQ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15753
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.040"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(19..2565)
                     /locus_tag="VXB71_001421"
     CDS             complement(19..2565)
                     /locus_tag="VXB71_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0451522.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(2688..3128)
                     /locus_tag="VXB71_001422"
     CDS             complement(2688..3128)
                     /locus_tag="VXB71_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0451523.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3103..3972)
                     /locus_tag="VXB71_001423"
     CDS             complement(3103..3972)
                     /locus_tag="VXB71_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0451524.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAYVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(4014..4742)
                     /locus_tag="VXB71_001424"
     CDS             complement(4014..4742)
                     /locus_tag="VXB71_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451525.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(4750..5229)
                     /locus_tag="VXB71_001425"
     CDS             complement(4750..5229)
                     /locus_tag="VXB71_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0451526.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(5240..5938)
                     /locus_tag="VXB71_001426"
     CDS             complement(5240..5938)
                     /locus_tag="VXB71_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0451527.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(5931..6197)
                     /locus_tag="VXB71_001427"
     CDS             complement(5931..6197)
                     /locus_tag="VXB71_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0451528.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(6263..7189)
                     /locus_tag="VXB71_001428"
     CDS             complement(6263..7189)
                     /locus_tag="VXB71_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0451529.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(7264..8079)
                     /locus_tag="VXB71_001429"
     CDS             complement(7264..8079)
                     /locus_tag="VXB71_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451530.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGVFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(8083..8403)
                     /locus_tag="VXB71_001430"
     CDS             complement(8083..8403)
                     /locus_tag="VXB71_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0451531.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(8610..8690)
                     /locus_tag="VXB71_001431"
                     /pseudo
     CDS             complement(8610..8690)
                     /locus_tag="VXB71_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8734..10731)
                     /gene="metG"
                     /locus_tag="VXB71_001432"
     CDS             complement(8734..10731)
                     /gene="metG"
                     /locus_tag="VXB71_001432"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0451532.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(10855..12114)
                     /locus_tag="VXB71_001433"
     CDS             complement(10855..12114)
                     /locus_tag="VXB71_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451533.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(12116..12817)
                     /locus_tag="VXB71_001434"
     CDS             complement(12116..12817)
                     /locus_tag="VXB71_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451534.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(12801..14000)
                     /locus_tag="VXB71_001435"
     CDS             complement(12801..14000)
                     /locus_tag="VXB71_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0451535.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            14265..15611
                     /gene="gor"
                     /locus_tag="VXB71_001436"
     CDS             14265..15611
                     /gene="gor"
                     /locus_tag="VXB71_001436"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0451536.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         4671 a         3543 c         2817 g         4722 t
ORIGIN      
        1 tttttatttt aggcttattt atgcatttcc gtattgaaga acaactgctt cgactgcagc
       61 tttttcacgg ctaatcaagt caacacgtgc tgcaatttcc ttgattccca taccgatgtt
      121 acggctaaga gcaaggtcag aaagttgcgg ctcaaagaac tccttgtatt ccgccaagcg
      181 ttgctgagtc ttaaatacat gagcaggaag gataacaaag ctatcaaagc tcatatctcc
      241 tccaagggct gccttaatcc aagcccagtt ttcacgcgcc caagaccaag ctgttttctg
      301 agttgcttga tgagctagga attggtaata ccaagcagac aagtcctgtg gtttgaccac
      361 aaatttgtcc ttccaagaag taatcaagtt ttggatatta tccgcatctg tactgtatgc
      421 aagagctgct gccaactggc gtttaaagac agcatctgtt gcgtgagtat aagtatcaag
      481 ataaagtgct aacaagtctt tagtctcatg atgtttcatc tcattaatca gaacttgtga
      541 acgaatagct gctgggagtt ctgcaagatt ctccttgtgt gttgcgaaga tttggctagc
      601 gacttgacga gcttctgcat catttgagcg aatcatcatc gaaacagcca gctgacgaac
      661 caattcatcc tcatctgatt ctccgtcttt agcttcaaaa ccaagacggt catagttatg
      721 acgagccaat ttagcaacca gtcctttgaa ggctgtttca gcatccgttc cttcatcaat
      781 aaagcgctca agggctgaaa tcacttgaga aacagctgaa accaccagat aagactcttc
      841 cttagcaagt ttatcaagaa ctggaagcaa gtctgcataa gaaatgtgcc ctgcctcagc
      901 caacaaacga cgttcttgaa caatttgcag tttgcttgtg ttatcaagtg tctctagctc
      961 agcaagaaca gcttctaaca agtctccttg atagtcggta atatagtggg cagtattttc
     1021 agtgttgaga cgaagagctc cttcattttc agcaagaaga gctgcgtagc cagggatttc
     1081 gatactttca gtttcgagtg tatcaggcaa gcctttccag ttgctattga ggggcaccac
     1141 ccagagacgg ttcttgtctt cgttctcacc gatgaagaat tgtttttgtg aaatcttcaa
     1201 gacatcattt tcaactttga cagtaagaac tgggtaacca ggctgttcca accaagaatc
     1261 catgaaggct gcgacatcac gtcctgacgc ttgaccaagg gcatcccaaa ggtcactacc
     1321 aatggtgttg ctgtattggt gtttttcaaa gtaggcatgc aaacctttag caaaatcagc
     1381 atctcctagc caacggcgaa gcatgtgcat gagacggctt cctttggcat agacgatagc
     1441 gccgtcaaag agtgtattga tttcatctgg atgtttaact tcgacgtgga cagactgaac
     1501 gccatcagta gcgtcacgtt caagagcaag aggtactcca cctgtttgga aatcttcaaa
     1561 gatattccag cttggttcga tggtatccac acagacgtat tccatcatat tagcgaaact
     1621 ttcattgagc caaaggtcat cccaccattt catagtcacg aggttcccaa accattggtg
     1681 agccaattca tgggccacaa caagggcaac ttgttgacgg ctagcaaatg tagagttctc
     1741 atcgacaacc aagtaaactt cacggtaggt cacaagaccc cagttttcca tagcaccagc
     1801 tgagaagtca ggaagggcga tgtggagaga ttgaggaatt ggatacttaa ctccatagta
     1861 atcttcgtaa aactcgatag agcgaacagc gatatccagt gagaaatcaa gatttgaaag
     1921 tggatgtgct ttggttgagt agacacctac cagggtacca tttttagttt tagcggtcac
     1981 cccttgcaaa tcaccagcaa caaaggccaa caagtaagaa gacatgcgag gtgttgtctc
     2041 aaacttccag atacctgttt ccttacggtt ttcaacatcg atttctggca tgtttgacaa
     2101 ggccaattca ccttctgctt ggtcaaagcg aagagagagg tcaaaagttg ctttggcttc
     2161 aggctcatcc acacatggga aagcttcgcg cgcaaaatgg ctctcgaact gagtagacaa
     2221 gacctccttc ttgactccat caactgtata ataagaaggg taaatccctg tcatgttgtc
     2281 tgtaatttta ccagaaaagg caagaaccaa ttcaacttga ccagcctcag ccaattcgat
     2341 atgaagggct tcattgtcat ggtcaactgt aaatggacga gcttgacctg caacttctac
     2401 agaggtgatt tccaagtctt tttggtggag ggagatgcgg tcactctgtg cttgaccagt
     2461 gatggtcact ttcccagaaa aagtcttggt ctcacgactc aaatctaaaa ataaatcata
     2521 atgttcagga acaaattgct taataaaatg ttcaactgct tgcatagttt tctcctattc
     2581 taagtttaag agctgctgct cttcttcaaa caaacttatt atatcatatt ttgcttgaaa
     2641 aaaaaggatt ggacagcgat ttccaaaact ttcttccttc taatagtcta cagtgggtag
     2701 accttgcgaa attcttctaa aacaaccttg ctttcaggtg taaaagtcag ccctacttca
     2761 cccaaacagt ctgtgaaaaa gtcctcatga acctggcgcc aataggcaag tgatttgtct
     2821 ccctcacctt ccttaaaggc atgttgcgca gaaacttgat tgaagagttc aacagaaacc
     2881 tttgtaattt cgacaatgca gacagactga ttttgactat ctaaaatgat atcgaaggtc
     2941 cctacttggg gaagtggttc gtcttctagt acatagaggt cataggctga tgctgttgct
     3001 gtcttttctc ctttaaacac caaatccgct aaaagatctg gttcaactcc aaaagcccaa
     3061 gcatcgattt catctccgat caaaggattg atttgcttgt atttattcca catttcttgc
     3121 ggtatcatgg gtactccttt gtaatttttt actttcttct tttatgtgtt taagatgatc
     3181 tggatggtca atctctaaat caaaaatctc tggaatagaa ctgtagtgga taatgcactt
     3241 gatacccaac tgattcattt tttgtatgaa agaagtattc agatagcctg ctacagcaaa
     3301 atcaatcttg ttctttcttg ctttatcctg catatctctt agcatatcta acattattgg
     3361 actttccata tcatgccatt gactgtttct catagtcgca aaaacaaagg aagtcaaatc
     3421 attcattcca actacaatct ttgaaatgcc cgtttccagt atactagata agtcaaaata
     3481 cgctgacggt aattcaatca tcgttccgac tttcccagta aaaccctgct gacgcaatac
     3541 tgtaatagct tgttttaatt ggtcggcatc attgacaaaa ggaaagataa gagatagatt
     3601 gggattggtt tgataaactt ctgtaacgac atatgcttca gcctgaaatt catccaaaca
     3661 cgccagtaaa cgcctggttc ctctatagcc aaacaaggga tgcccttcgt caaaaaactc
     3721 tctagtcccc actaaacaat tggcttctgt attcgttaat tcagaaaaac gataccaaac
     3781 ttcttcatct gagtacaggg agcagatagt ctctagataa tcttttacaa attgctgaca
     3841 acttgctaat atgatgtttt gattaagctc tctcaacaaa tattccccac gaatcatgcc
     3901 gacgtggtga aatagttgag gataaatttt ttcaagaatt ttttcgccac taagggcaag
     3961 ttgatttctc atagccattc acctcgtctt aaaagataca atatcatata taattatatc
     4021 aaaatttcct ctagttcaaa agcttcataa ggttcagata actcatatcc taaaaattct
     4081 gctacttttt tggaagcctc attatgagca tcccaaagtg gaaacatatc tctatttaaa
     4141 ctctctagaa tcattgcagc accaagcttt ttagcaaatc catttccttg ttcgtttggt
     4201 ctagttgcaa cttccacttc aactgcttta cggtaaacta accctgagga aatcccagca
     4261 atcagttcat tatttttaag aatcacaaag ccaaatccac cttttaaaac aaaatcctga
     4321 taggactcaa aatccccctg taaatcctgt gaccattctt ccgtagaaaa gcagttataa
     4381 atatgattat caataggcac aatattgtaa ccttcctcta aatgagtaac tagattattt
     4441 aaaaattcaa cttgaaaatt tgccttatct ttaaaagaat agcgagtaaa agaatttagc
     4501 cccacttttc gatgcagaaa atcttgccaa ttagtatttt ctgaaataat aatcttataa
     4561 tctaaaccat attttctaac aaaatcttcc caaaatctgg aatccaactc ccctgctagg
     4621 tatagaaaat tcccaacatc ataaaagctt gttgtcctat cattgtttcg gtagacagtt
     4681 ccaatttgag atttaagacc atagagaacc atatttttct tccatgtttt aaatagttcc
     4741 attatccctc tacttcacct tccaattcat gtaagaagtc ttgtccagtt ctggcaatcc
     4801 taataattca gacttaacct tcaagactaa tggcgatgca ttttcttctg taatctcttg
     4861 aatatccatc caaatatatc caagtgaatc attcgcacca tcagacacag cttccgaaat
     4921 cgtaacttga ggtgcactct cattcatttc aacatcatac aaggctatga catggtgaac
     4981 cataaaattt tttaactctt ccctgacgaa aacatcgtag attcgaggat tagagtagct
     5041 tctaacagta aatcccgtct cttccataac ttctctagtc agcgtttccg tcagtccttc
     5101 accaagttgc tgactgcctc caggtagatc ataccgatgt tgataagggc ctctcgtttt
     5161 ttcaatgcaa agtaactttc cattttcaaa gcaaacacag tagaccccaa agtgattttt
     5221 gatttccatc caactcctcc tacttcaaag accagccacc atctattgtc agaatttgtc
     5281 cctgcatggc agatgccttt ccactggcca aaaagagact gacttctgcc acttcctctg
     5341 gttcaatcca gcgcttgatt ggggtttcac tagccaccca gtcagctaag ccacctgtct
     5401 caaaatccgc agcggtcata gctgtcttga ctgctcctgg agcgatacca aagacctgaa
     5461 tcctagcttc agcatagtct agagccaact gcttggtgaa gccagccaag gcatgcttgg
     5521 atgaagtata ggcgtgacca cctccacctg ctaggctaga agcaatggaa cacatattga
     5581 tgatgattcc ctttttattt tccagcattt gtgtcaaata ataccgagtc aactctactg
     5641 gaataatgta gttgatttca aaaatctctt gaatgtcctg cgccgtttgt tccaacagtg
     5701 gtttgtaagc atccaaaact ccggcagtat tacacaaaac atccacctga gggcaccagt
     5761 caaaaatagg ttccaagtcc aaggtcaaat ctctctgtaa aaagtgaaaa tcaccctcta
     5821 agagtggctt ttcaccttgg tcaactccat aaacttgata gcccttctct aaaaagaggc
     5881 gagcttgagc caatccgatc cctgaactca ctcctgtaat gagtacacgt ttagtcatgc
     5941 acttctaccc aatccgttgc caaaacatca caaactgtcg ggctccacat ggaaaaacct
     6001 tctccttctc cagaaacgtt gattaggaaa taaggtgtca tttcaagtgc aagcccattt
     6061 tgctcgatgg tatcaaagag ttggacatag ttttccgcac ctccccaacc agttcgtaca
     6121 tattttctct tagcctttaa cccaggcagg atctcttcaa atgtcatgtt tttctccttt
     6181 aattctacat tcttcattta attatagcaa aaaaccactt tatacggctt tttgactgtg
     6241 agttattcaa acctgctact acttacggca aattattccc tgcagcaaga taaatttcat
     6301 accattcttt tcttgttaag ctaaagtttg ccgctcggct aacttctctc aagtgcttag
     6361 gatttgttgt acctacgact gcctgcattt ttgctggata acgcaatatc caagaaatgg
     6421 caatagttga agaggttact ccatatttaa tagctaaacg atcaagtact tgatttaaag
     6481 cttgaaattt ctcatttcca acaaagttcc ctttaaaata cccgaattgc aagacagacc
     6541 atgcttgaat gaccacatcg tgtaattggc aatattcaaa aatgctgcca tctcgcatag
     6601 ctgcttgact atcttccata ttaacatgaa aagctgattc aaatcctgga gtaaaagccg
     6661 cactcaattg tagctgatta acagctaacg gctgcttgac atctttttta agcaactcca
     6721 tcatcatagg attttgatta gaaactccaa aatctcgaac tttaccttgt ttataaagga
     6781 gatcaaaggc ttctgctact tggtcagatt ccatcaaagc atctggtcga tgaaggagca
     6841 agctatctag atgatcaatc ttcaatcttt gcaaaatacc gtctactgat tttataatat
     6901 agtccttaga aaaatcaaaa taggtaaatt cttcaatgcg aatgccacat ttggactgaa
     6961 tccacatctt ttctcttaaa tctggacgat tttttaggac aagacctaac agttcttcac
     7021 aacgaccacg accataaata tcagccaagt cgaaggcatt gattccaaca gaaagtgctg
     7081 tttctacaag ctcttcaact tcttttacag atttatcttt tattctcatc attccgagaa
     7141 caatttctga taattctttg tcatcttgac caagagttat gtatctcatc aaatttttct
     7201 cctttaattt ctaacattct tcccttcatt ataacaaaaa accgctttgc aacggctttt
     7261 tgactatact tcactccatt ttatcttctt aaacccacgg aacaagacaa agattccaat
     7321 aaagaggaca gctaaaggaa taacttttgt aaggaaaaca tttgaaattc ccatccactc
     7381 ataataacgg agcagagaac ccaccacaag atgggcaata atcatactga caaatggacg
     7441 aaagaccgct tctttccaat tccaaatacc gataactagc gaaatcgtaa agacagacaa
     7501 actatcccag ggagccggaa tataaaagac tccttcttgt atgaagcttg ccattcctac
     7561 atatcctaaa acaactagaa gaactatagt cccaacaaca atgtaagtgc caattttcat
     7621 tttaggagaa tcttggacta aacttcttcg taaaattgtg gccacaagtc caaatccaat
     7681 cagaaaaata agaagttgcc ctaaaaatgt gagcaaattg actgttaata gaggaccttt
     7741 agaaaaatca cttagtagtt gataataacg taataccgcc aggacaagaa ttggcgtcaa
     7801 aagggactct ttgatagaac tgcgaggtgc tcccttgaga atctctttca ttattttttt
     7861 aggattctta cctagataat cctctgcact catgccatct cgttctgctt ctgagaaatc
     7921 tagcatcatc aaatagatct gctctctgag atagtcttca tcatagagaa atccagcaag
     7981 attaaaactt tcccacaact cctcaaaata cttttgattc tcctcagaaa actcatgtag
     8041 caaagcgctt gtttcttcgt aatacttcat tttcttcatg gtttaacccc cattcttaat
     8101 cccttctact ttttgactca aatcgtccca ttgttgccaa aagactgaga cacgctcttc
     8161 tccttctttc attaatgaaa aatacttccg atctggacca tctggcgacg ggcgcatgtc
     8221 gcctcttatc cattgatttt tttctaactt ttgcaacaaa ggataaatag ttcctggaac
     8281 gatagtatca aatccagcct ctcgcaaagt ctgaaccaac tcataaccat accgctcttt
     8341 ttgaccaatc atatccaaga cacaaccttc aagaacacct tttaatagct gagtttcttt
     8401 catcactttt cccttctaat ctattttgta atacctacta gtaacttcac ctatagtata
     8461 tcacttctac actagtttgt aaagcataat agttaatact cttcgaaaat ctcttcaaac
     8521 cacgtcagcg tcgccctacc ttatgtatgg ttactgactt cgtcagtttc atctacaacc
     8581 tcaaaactgt gttttgagct gacttcgtca gtttcatcta caacctcaaa actgtgtttt
     8641 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta taaataaaaa
     8701 aacagaacta gcctgaacta gtcctgtcta cttttaccca atcacacttc catttggtac
     8761 agctggatca actgtgagaa gggttaattt gccatcatgt tcagctgaga gaatcatacc
     8821 ctggctgaca tattttttca tcattttacg tggtttgagg ttagcaatga tttgaacttt
     8881 cttgccgacc aattcttgtt catttggata gtattttgca attcctgaaa gaatctgacg
     8941 atcttctcca tcaccagcat ccaagcggaa ttgaagcaac ttatctgaac cttctacttt
     9001 agacacttct ttgacttctg cgacacggat ttcaaccttg tcaaagtctt caaacttgat
     9061 ttcatccttg tttagtttga gctcaacttc gtccggattc cattcttttt cgactgctgg
     9121 tttattgcct tccatttgtt ccttgatata ggcgatttct tcttccatat ttagacgtgg
     9181 aaagataggt gttcctttgg caactacagt cacatctgct gggaagtcag ccaaactcaa
     9241 gttttcaaga ctagaaactt cttccaaacc aagttgagtc aaaactgcac gactagtttc
     9301 catcataaat ggttcaatca agtgagcaac tacacgaatg ctggctgcca agtggctcat
     9361 gacacttgcc aattggtcac gaagagcttc atccttggcc aagacccatg gtgcagtctc
     9421 atcgatgtat ttattggtac gagagatcag agtccagact gcttcaagcg cacgtggata
     9481 gtcaactgct tccatgtgtg tatggaagtc tgcgattgat tgttctgcaa cctcagcaag
     9541 aacatgatca aattcagtca caccttctac ataggcaggg atttgtccat caaagtactt
     9601 attaatcatg gaaaccgtac ggttaaggag gttcccaagg tcattagcca attcatagtt
     9661 gatacggccg acatagtctt caggagtaaa ggttccgtct gaaccaactg gaaggttacg
     9721 catgaggtag taacgaagtg gatctagtcc ataacgctct accaacattt cagggtaaac
     9781 gacattccct tttgacttag acatttttcc gtctttcatg acaaaccaac catgggcaat
     9841 caaacgatca ggtaatttaa catccaacat cataagaagg attggccagt agatagagtg
     9901 gaagcgaagg atatcttttc ctaccatatg gaagactgtt ccattccaga acttgtcaaa
     9961 gttaccatgt tcgtcttgag cgtagccaag agctgtcgca tagttaagaa gggcatcaat
    10021 ccaaacgtag acaacgtgtt ttggatttga tgggacaggc actccccatg taaaggttgt
    10081 acgagatacc gccaaatctt ccaaacctgg ctcgatgaag ttgcgtagca tttcattaag
    10141 gcgaccatct ggcgtgataa attcaggatg agctttgaaa aattcgacca aacggtcttg
    10201 gtatttgcta aggcgaagga agtatgattc ttcagaaacc cattcaacct catgacctga
    10261 tggagcaata ccaccagtca catttccagc ttcatcacgg aaaacttctg ccagctggct
    10321 ttctgtaaag aattcttcgt ctgatactga ataccaacca gagtattcac ccaagtagat
    10381 atcatcttga gcaagtaagc gttcaaagac ttgtgcgaca actttttcat ggtagtcatc
    10441 agttgtacgg ataaatttat cgtatgagat atctagtaat tgccagagtt ctttaactcc
    10501 aaccgccatt ccatcaacat aggcttgagg tgtaatacca gcttcttccg ctttctgctg
    10561 gattttctga ccatgttcat caagacctgt cagataaaat acatcgtagc ccatcaggcg
    10621 tttgtaacgt gctaggacat cacatgcgat agttgtgtag gcagaaccga tatgaagttt
    10681 cccagatgga tagtaaatcg gcgttgtaat ataaaaattt ttttcagaca taatttttcc
    10741 tttccaggca aatgaaacct gtttttctaa cacttcatta tatcacattt ttaatgaatt
    10801 tcgataggga aatccataca aaaacaagat agacgagtgt ccatcttgtt gatctcattc
    10861 ataacgaagg gcttcaattg gatcaagttt cgatgccttg ttggctggca agactccaaa
    10921 aatcatacca acactagccg aaactgcaag actaaatagg gcaactggga ttgatactcc
    10981 aacttctata ccttctatta aaccttgcag taacaaacct gctaaggcag ttaaaccact
    11041 tgcaattgtc aagccaatta agccacctaa caaggtcaaa atcatggatt caatcaaaaa
    11101 ctgaattaaa atattggcac gtgttgcgcc caaagcctta cgaagaccaa tctcacgagt
    11161 gcgctctgtc accgaaacca gcatgatgtt catgacacca gttcctccaa caaagagaga
    11221 aatccctgcg atggaactaa taatcgtcgt cataaaacta aacgattgtt gaatttctgc
    11281 aaatacaacg gactcatctg ccacctggta ttctccctgt tgtaagcctg caagctctgt
    11341 catttttcgt gccagttctg gacccagagt tggggttaaa ctggtatcat tcactcgaaa
    11401 gacaatacta gctatttcat ctatattaaa attcgcagca agggagatat tggtagtaat
    11461 aggcaagcca ccaaacccat atatttttga ccttttagcc tccggactag tataaacccc
    11521 aatgacccgg taactaaatc cattgacttc tacaaccttg ttaatagcct cttgaggaga
    11581 ttcaaataaa ctaatggaca attcctcatc tagcaaaata acacttgcaa actctttgaa
    11641 atcttgctct ctcagactac gacctgcaat aatttcattc ttaacagcgt ccatgtaagt
    11701 tctgtttcca cctgtcaaat tagcattctc aaccttttta tcttgatagg tcaagatggc
    11761 attcgttgaa ttggttacat agtaactatc cactcccttc agtttagctg cctcttggac
    11821 ccaggattct tgcggttttg gcggttcaac aggaatttcc tcttcctttc cagaaaccgt
    11881 aaaagatgat tgtttctgag taaaagaacc atctttactt tttttaggag agaaaaagac
    11941 gctaatattt ttctgagatt tagtcatatc tttattgact tgacgagata gggaatcacc
    12001 caaagccata atcacaacaa ctgatgaaac accgataata atcccaatca tagtaagcaa
    12061 agaacgcatc ttgtgagcca tgatagatga aaaggcaaat ttcagattct gcatcttagt
    12121 tttcctcctt tcctaactga gcactgtcag acgaaatgac cccatcccga atgacaatct
    12181 gacgtttagc ataggcagca atctcaggct catgcgttac catgataatg gtttttcctt
    12241 ctttattcaa atcaaccaat aattgcataa tttggttacc tgttttggta tccaaggctc
    12301 ctgtcggttc atccgctagg ataatagaag gattgtttac caaggcacgc gcaatggcta
    12361 cacgttgctt ttgaccacca gataattctg aaggtaaatg gtgactacgt tctgtcaatt
    12421 caaccttgtc taaatattcc tcagccaact tgcgacgttt tgaagacgaa actcctgcgt
    12481 aaatcaaggg caattctaca ttttgcagag cattgagctt cgatagaaga aagaactgct
    12541 gaaagacaaa accgatttgt tggttacgga ccttagccag ttgtttttca ccaagcccag
    12601 ccacttcttg accttcaaga taatattctc cactggttgg tgtatccaac atgccaatcg
    12661 tattcatcag agtggactta ccagacccag atggtcccat gatggctaca aattcaccct
    12721 cattcacttc tagattgata tttttgagaa cctgcagttc ttggtcacca ttacggtagc
    12781 ttctgaagat attttttaga ctaattagtt gcttcatcag ccttcacctc ttttccttct
    12841 tccaaggaag atgttggatt actgatgacc ttagcaccat tcgttaaacc agaagtgatt
    12901 tcttgatttt ctgcgtcagc atttcccaat gaaacctcaa cttttttagc cttttgttgt
    12961 tcatccacaa tccagacata atttttacta tcatccatta ctagactgct aacaggaaca
    13021 agaatagcct tagttttgct tttaacctca atgttgacag aaaaaccctg tttcaaatca
    13081 ccaacctcgc ctgtcacatc aatagtataa gggtatttag aacctgtatt attcccggct
    13141 gctggactag ctgcttcacc attgttttta ggatagtcag aaatatagct taatttccca
    13201 gtccattttt tatcaggata cactttagaa gtaaagctta cttcttgacc tacagaaagg
    13261 ttggctagat tgtactcaga caattctccc ttgacttgta aattttcatt gctgacaata
    13321 tgaaccataa cttggctcgc ccctgttgga gatttagaaa cattgctatt gacttcgact
    13381 acagttccct ctagggtact gagaacagtt gttgcatcca attgactttg agccttgctt
    13441 aattgcgctg cagcatctgc acgcgcatca cgggcatcac ccaattgagc gtcaatagaa
    13501 gcaacagaat ttccagccac tggagttggg ctttgcaccg ttgcatcttc tcctcctact
    13561 ggcgctggta actgtggagc cggagctgaa gcggcttcat ttcgtgcttg attgagttca
    13621 ttgatatgac gatctgcctt agctactgct cgactagctg aatcataggc cgcctgcgct
    13681 tctgaactac tgtacttgac taaagcctgc ccttcgctga ccttatcgcc cacagaaaca
    13741 aggatttcat ctaaatcacc cttactagca tcaaaataaa catattgttc attttttgct
    13801 gttactgtcc ctgacaataa aacagaggag gccacgcttc cttccttggc aacaacaaga
    13861 tgagtaggct catcttttag agcagtctga gaaggttgtc taaagagtaa aatcccccca
    13921 gcacccaata caactacact cgcagcaccg attgctgcat acagttgcca ctttttagct
    13981 ttaccattct ttttcttcat aatgaaactc cttttctttt ttacaatact ttgctattat
    14041 accaaatttc cctccagcaa acaatacagt tcaggattaa acaatcgttc ggaattttgc
    14101 ttttctattg tactagatat ataatacact atcttgactt atttggcaag cttttttgca
    14161 attttttgtg cgtagcagat ttttgcaatc aaatcaaaaa aagaataaaa tataactatc
    14221 aaaaaagacg ctctactatt taaaagatta caaaggagtt ttcaatgaga gaatatgata
    14281 tcattgctat cggtggaggt agcggaggaa tcgctaccat gaaccgtgct ggtgaacatg
    14341 gagccaaagc agccgttatt gaggaaaaga aattaggtgg aacctgtgtc aacgtcggtt
    14401 gtgttcctaa aaaaatcatg tggtacgggg cgcaaatcgc tgagactttc catcaatttg
    14461 gagaagacta cggctttaag actactgatc ttaactttga ctttgcaacc ctacgtcgca
    14521 atcgtgaagc ctacattgat cgcgctcgtt cttcttatga tggtagtttt aaacgcaacg
    14581 gtgtagactt gattgaaggt catgctgaat ttgtagattc tcatactgta agcgtaaatg
    14641 gtgaactgat tcgtgctaaa catatcgtga ttgctacagg tgcccatcca agtattccta
    14701 atattcctgg tgctgagcta ggtggctctt ctgatgatgt atttgcctgg gaagaacttc
    14761 cagagtcaat tgccattcta ggcgctggtt atatcgccgt tgaattagct ggcgtactcc
    14821 acacttttgg tgtcaagaca gatctctttg ttcgccgcga tcgtccttta cgtggttttg
    14881 attcctacat cgttgaaggt ttggtcaagg aaatggaaag aacaaactta ccacttcaca
    14941 ctcacaaagt ccctgtcaag ttagaaaaaa ctactgacgg cattaccatt catttcgaag
    15001 atggtactag tcacacagct agccaagtta tctgggctac aggtcgccgt ccaaacgtta
    15061 agggcttgca acttgaaaaa gctggagtga ctctgaacga acgtggcttt atccaagtgg
    15121 atgaatacca aaatactgtt gttgagggaa tctatgctct aggtgatgta acgggcgaga
    15181 aagaactgac tccagttgca atcaaggccg gacgtaccct atctgaacgt ctctttaacg
    15241 gaaaaactac tgcaaaaatg gattactcaa ctattccaac tgttgtcttt tcacaccctg
    15301 ctatcggaac tgttggtttg acagaagagc aagctattaa agaatacggt caagaccaaa
    15361 tcaaggttta taaatcaagc tttgcatcta tgtactctgc ttgcactcgc aaccgtcaag
    15421 aatcccgttt caaactcata acagctggtt cagaagaaaa agttgtcgga cttcatggaa
    15481 ttggctacgg cgttgatgaa atgattcaag gatttgccgt tgctatcaaa atgggagcaa
    15541 ccaaggctga ctttgatgca actgtggcaa ttcacccaac tgcatctgaa gaatttgtaa
    15601 ccatgcgtta atcgaaacaa aagaagcaaa gcaaaaaaca cttctaaata tcaaaaagcg
    15661 agtatttccg tagttggaga tactcgtttt cttatgtttt attttatagt atgttgaagt
    15721 aagatatgca aaaatcaatt aacaaaccat agc
//
LOCUS       DAVLAQ010000041        15019 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000041 DAVLAQ010000000
VERSION     DAVLAQ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.041"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            88..1026
                     /gene="msrB"
                     /locus_tag="VXB71_001437"
     CDS             88..1026
                     /gene="msrB"
                     /locus_tag="VXB71_001437"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0451537.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1084..2808
                     /locus_tag="VXB71_001438"
     CDS             1084..2808
                     /locus_tag="VXB71_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451538.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPIDKGSIDL
                     YRDGSSPRNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2810..4558
                     /locus_tag="VXB71_001439"
     CDS             2810..4558
                     /locus_tag="VXB71_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451539.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4905..6164
                     /locus_tag="VXB71_001440"
     CDS             4905..6164
                     /locus_tag="VXB71_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0451540.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6240..6375
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6414..6914
                     /locus_tag="VXB71_001441"
     CDS             6414..6914
                     /locus_tag="VXB71_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0451541.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6990..7358
                     /gene="rplL"
                     /locus_tag="VXB71_001442"
     CDS             6990..7358
                     /gene="rplL"
                     /locus_tag="VXB71_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0451542.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7545..7715
                     /locus_tag="VXB71_001443"
     CDS             7545..7715
                     /locus_tag="VXB71_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451543.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            7715..7963
                     /locus_tag="VXB71_001444"
                     /pseudo
     CDS             7715..7963
                     /locus_tag="VXB71_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            7977..8317
                     /locus_tag="VXB71_001445"
                     /pseudo
     CDS             7977..8317
                     /locus_tag="VXB71_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8310..8690
                     /locus_tag="VXB71_001446"
     CDS             8310..8690
                     /locus_tag="VXB71_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0451544.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            8703..8846
                     /locus_tag="VXB71_001447"
     CDS             8703..8846
                     /locus_tag="VXB71_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451545.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            8939..9526
                     /locus_tag="VXB71_001448"
     CDS             8939..9526
                     /locus_tag="VXB71_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0451546.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            9728..9865
                     /locus_tag="VXB71_001449"
     CDS             9728..9865
                     /locus_tag="VXB71_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0451547.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            10044..12653
                     /locus_tag="VXB71_001450"
     CDS             10044..12653
                     /locus_tag="VXB71_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0451548.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKSMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            12686..14626
                     /locus_tag="VXB71_001451"
     CDS             12686..14626
                     /locus_tag="VXB71_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEV0451549.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGISSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRAPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAADHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            14623..>15019
                     /locus_tag="VXB71_001452"
     CDS             14623..>15019
                     /locus_tag="VXB71_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451550.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSIL"
BASE COUNT         4738 a         2474 c         3144 g         4663 t
ORIGIN      
        1 aacatatata cggtaaggtg acgctaacgt ggtttgaaga gattttcgaa gagtattagt
       61 taaaaacgtg ataaaggaga aataaagatg gcagaaattt atctagcagg tggttgtttt
      121 tggggcctag aggaatattt ttcacgcatt tctggagtgc tagaaaccag tgttggctac
      181 gctaatggtc aagtcgaaac gaccaattac cagttgatca aggaaacaga ccatgcagaa
      241 acggtccaag tgatttacga tgagaaggaa gtgtcactca gagagatttt actttattat
      301 ttccgagtta tcgatcctct atctatcaat caacaaggga atgaccgtgg ccgccaatat
      361 cgaactggga tttattatca ggatgaagca gatttgccag ctatctacac agtggtgcag
      421 gagcaggaac gcatgctggg tcgaaagatt gcagtagaag tggagcaatt acgccactac
      481 attctggctg aagactacca ccaagactat ctcaggaaga atccttcagg ttactgtcat
      541 atcgatgtga ccgatgctga taagccattg attgatgcag caaactatga aaagcctagt
      601 caagaggtgt tgaaggccag tctatctgaa gagtcttatc gtgtcacaca agaagctgct
      661 acagaggctc catttaccaa tgcctatgac caaacctttg aagaggggat ttatgtagat
      721 attacgacag gtgagccact cttttttgcc aaggataagt ttgcttcagg ttgtggttgg
      781 ccaagtttta gccgtccgat ttccaaagag ttgattcatt attacaagga tctgagccat
      841 ggaatggagc gaattgaagt tcgttctcgt tcaggcagtg ctcacttggg tcatgttttc
      901 acagatggac cgcgggagtt aggcggcctc cgttactgta tcaattctgc ttctttacgc
      961 tttgtggcca aggatgagat ggaaaaagca ggatatggct atctattgcc ttacttaaac
     1021 aaataaaaca gagagtgggg cttcccactt tcttcatttc tagaatatga atagaaggga
     1081 tttatgaaac acctattatc ttacttcaaa ccctacatca aggaatcaat tttagccccc
     1141 ttgttcaagc tgttagaagc tgtttttgag ctcttggttc ccatggtgat tgctgggatt
     1201 gttgaccaat ctttacctca gggagatcaa ggtcatctct ggatgcagat tggcctgctc
     1261 cttatctttg cagtaattgg cgttttagtg gccttgatag ctcaatttta ctcagcaaag
     1321 gcagcagtag gttttgctaa ggaattgaca aacgatcttt atcgtcatat tctttccttg
     1381 ccaaaggaca gcagagaccg tctgacaact tctagtttgg ttactcgctt gacttcggat
     1441 acctaccaga ttcagactgg tatcaatcaa ttcctgcgtc tctttttacg agcgcccatt
     1501 atcgtttttg gtgccatttt tatggcttat cgaatctcag ctgagttgac tttctggttc
     1561 ttagtcatgg ttgccatttt gaccattgtc attgtagggt tatctcgatt ggtcaatcct
     1621 ctctacagta gtctcagaaa gaaaacggac caactggttc aggaaacgcg ccagcaattg
     1681 caagggatgc gggttattcg tgcttttggt caagaaaaac gagagttaca gatttttcaa
     1741 acccttaacc aagtttatgc tagattacaa gaaaagacag gtttctggtc tagtttatta
     1801 acacctctga cctatctgat tgtcaatgga actcttctcg ttattatctg gcaaggctat
     1861 atttcaattc aaggaggagt gctcagtcaa ggtgctctca ttgctcttat caattacctc
     1921 ttacagattt tggtggaatt ggtcaagcta gccatgttga taaattctct caaccagtcc
     1981 tatatctcag ccaagcgaat cgaggaggtc tttgcggaat ctcccgaaaa catccattca
     2041 gaattagaac aaaagcaagt taccagtggt cgggttttac aagtccaaga attgactttt
     2101 acctatcctg atgcggccca gccttctctg agatacattt cctttgatat gactcaagga
     2161 caaattctag gtatcatcgg gggaacgggt tctggtaagt caagcttggt gcaactctta
     2221 cttggacttt atccaataga taaggggagc attgaccttt atcgagatgg atctagtcct
     2281 cgtaatttag agcagtggcg gtcttggatt gcttatgttc cccaaaaggt cgaacttttt
     2341 aagggaacta ttcgttccaa cttgacttta ggtttaaatc aagaagtgac tgatcaagaa
     2401 ctctggcaag ccttggaaat tgctcaagct aaggattttg tcagtgataa ggaaggactc
     2461 ttggatgctc tagttgaagc aggagggcga aatttctcag gtggacaaaa acaaaggctg
     2521 tctatcgcac gagcagtctt gcgccaggct ccgtttctca tcctagatga tgcgacctca
     2581 gcactggaca ccattaccga gtccaagctc ttgaaagcta ttagagaaaa ttttccaaac
     2641 atgagcttaa ttttgatctc tcaacgaacc tcgactttac agatggctga ccagattctc
     2701 ctcttggaaa aaggtgagtt gctagctgtt ggcaagcacg atgacttgat gaaatccagt
     2761 caagtctatc gtgaaatcaa tgcatcccaa catggaaagg aggactagaa tgaaacgaca
     2821 aactgtaaac cagacgctca aacgtttagc cgtagattta gcaaaccatc ccttcctcct
     2881 tttcctagcc tttctaggaa ctattgccca agttggctta tcaatttatc tacctattct
     2941 gattgggcag gtcattgacc aagtcctagt ggctggttca tcaccagttt tttggcagat
     3001 ttttctccag atgctcttgg tggtaatagg aaatactcta gtacaatggg ccaatcctct
     3061 cctctataat cgtctaatct tctcttatac cagagattta cgagagcgaa tcatccataa
     3121 actccatcgg ttaccgattg cttttgcgga tcggcaaggc aatggagaga tggtcagtcg
     3181 tgtaaccacg gacatcgaac agttggcagc tggcttgacc atgattttta accaattttt
     3241 cattggtgtt ttgatgattt tggttagtat tctagccatg ctccaaattc atctcctcat
     3301 gactctctta gtcttgctgt tgacgccact gtccatggtg atttcacgct ttattgccaa
     3361 gagatcctat catctcttcc agaagcaaac agagacgagg ggaattcaga ctcagttgat
     3421 tgaagaatcg cttagccagc agactataat ccagtccttc aatgctcaaa cagaatttat
     3481 ccaaagattg cgtgaggctc atgacaacta ctcaggctat tctcagtcag ccatctttta
     3541 ttcttcaacg gtcaatcctt cgactcgctt tgtaaatgca ctcatttatg cccttttagc
     3601 tggagtagga gcttatcgta tcatgatggg ttcagccttg accgtcggtc gtttagtgac
     3661 ttttttgaac tatgttcagc aatacaccaa gccctttaac gatatttctt cagtgctagc
     3721 tgagttgcaa agtgctctgg cttgcgtaga gcgtatctat ggagtcttag atagccctga
     3781 agtggctgaa acaggtaagg aagtcttgac cagtgaccaa gttaagggag ctatttcctt
     3841 taaacatgtc tcttttggct accatcctga aaaaattttg attaaggact tgtctatcga
     3901 tattccagct ggtagtaaga tagccatcgt tggtccgaca ggtgctggaa aatcaactct
     3961 tatcaatctc cttatgcgtt tttatcccat tagctcggga gatatcttgc tggatgggca
     4021 atccatttat gattatacac gagcatcatt gagacagcag tttggtatgg tgcttcaaga
     4081 aacctggctc acacaaggga ccattcatga taatattgcc tttggcaatc ctgaagccag
     4141 tcgagagcaa gtaattgctg ctgccaaagc agctaatgca gactttttca ttcaacagtt
     4201 gccacaggga tacgatacca agttggaaaa tgctggagaa tctctctctg tcggccaagc
     4261 tcagctcttg accatagccc gagtctttct ggctattcca aagattctta tcttagacga
     4321 ggcaacttct tccattgata cacggacaga agtgctggta caggatacct ttgcaaaact
     4381 catgaagggc cgcacaagct tcatcattgc tcaccgtttg tcaaccattc aggatgcgga
     4441 tttaattctt gtcttagtag atggtgatat tgttgaatat ggtaaccatc aagaactcat
     4501 ggatagaaag ggtaagtatt accaaatgca aaaagctgcg gcttttagtt ctgaataagc
     4561 cattctcttt tgaaagttta tggacgaaaa aagttgcctt cgagtgactt ttttgttaca
     4621 atagctagaa aaattgttca ctgtaatact caatgaaaat caaagagcaa actaggaagc
     4681 tagccgtagg ttgctcaaag cacagctttg aggttgtaga taagactgac gaagtcagtt
     4741 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa cactgttttg
     4801 aggttgcaga tagaactgac gaagtcagta accacaccta cggcaaagtg aatctgaagt
     4861 ggtttgaaga gagtacaact tgtcttttaa aaaaggagtc tataatgaaa gtctttcagc
     4921 atgtaaatat cgtgacttgt gatcaaaatt tccatgttta tcttgatgga atcttagcag
     4981 tcaaggattc tcaaatcgtc tatgtcggtc aagataagcc agcgttttta gaacaagctg
     5041 agcagattat agactatcag ggagcttgga ttatgcctgg tttggtcaat tgtcacaccc
     5101 attctgcaat gacaggtctg agagggatcc gagatgacag caatctccat gaatggctca
     5161 atgactatat ctggccagca gaatctgagt ttactcccga catgactacc aatgcggtca
     5221 aagaagccct gacagagatg ctccagtcag gaacaacaac ctttaacgat atgtataatc
     5281 ccaatggtgt ggatatccag caaatttatc aggtggtgaa aacttccaag atgcgttgtt
     5341 atttttctcc gactctcttt tcttcagaga cagaaacaac tgctgagact ataagcagaa
     5401 ctcgatccat catagacgaa atcttaaaat ataaaaatcc aaatttcaag gttatggtag
     5461 cacctcattc tccgtatagc tgcagtagag acttgctgga agcgagtttg gaaatggcaa
     5521 aagagctaaa tattccgctc catgtccatg tggcggagac caaggaggag tcaggaatta
     5581 tcctcaaacg atacggcaaa cgcccccttg cttttcttga agaactgggt tatttagatc
     5641 atccgtccgt atttgctcac ggggtcgaat taaacgagag agaaattgaa cgcttggcat
     5701 cttctcaagt ggctatcgcc cacaatccta tcagtaacct caaactggca tcaggaattg
     5761 ctccaattat ccagctccaa aaagcgggag tagcagtcgg aattgcgact gactcggttg
     5821 cttccaataa caatctagat atgtttgagg aaggaaggac tgcagctctt cttcagaaga
     5881 tgaaaagtgg ggatgccagc cagtttccaa tcgaaacagc tctcaaggta ctgacaatcg
     5941 aaggggctaa ggtccttgga atggaaaatc agataggaag tctggaagtc ggcaagcaag
     6001 cagattttct ggtcattcaa ccacaaggga aaattcatct ccaacctcag gaaaatatgc
     6061 tgtctcacct ggtttatgca gttaaatcta gtgatgtaga tgatgtttat atcgccggag
     6121 aacaggttgt taagcaaggt caagtcctga cagtagaact ttaaaagaaa aatcacgaaa
     6181 aattttaaaa aaagtttgca aaaatcttgc attctttttt tgactatgct atacttatat
     6241 acggtttaaa aaaactgcct aagacagtag gggagatcga ctcataaata tcctaccgag
     6301 gacaaaacgt atcatgtaaa aagaagcgta ttgtactttc gtgtctaggt ttgggcgcgt
     6361 ttttcttttt gaaaaattcc ccaagcaaaa taattacgga ggtgaacaca ctaatgagtg
     6421 aagcaattat tgctaaaaaa gcggaactag ttgacgtagt agctgaaaaa atgaaagctg
     6481 ctgcatctat cgtcgttgta gacgctcgtg gtttgacagt tgagcaagat acagttcttc
     6541 gtcgtgagct tcgtggaagc gaagttgagt ataaagttat taaaaactca atcttgcgtc
     6601 gtgcagctga aaaagctggt cttgaagatc ttgcatctgt atttgttgga ccatctgcag
     6661 tagcattttc taatgaagat gttatcgcac cagcgaaaat cttgaacgac ttttctaaaa
     6721 acgctgaagc acttgaaatt aaaggtggtg caatcgaagg cgctgtcgca tctaaagaag
     6781 agattcttgc acttgcaact cttccaaacc gcgaaggact tctttctatg ctcctttctg
     6841 tacttcaagc gccagtgcgc aacgttgctc ttgcagtcaa agcggttgca gaaagcaaag
     6901 aagacgcggc ttaatcttaa gctacatagc gtagcctagc tacgaaaaaa actattataa
     6961 aatttaaaac ttatttggag gaaataacaa tggcattgaa cattgaaaac attattgctg
     7021 aaattaaaga agcttcaatc cttgaattga acgaccttgt aaaagctatc gaagaagaat
     7081 ttggtgtaac tgcagctgct cctgtagctg ttgctgcagc tgatgcagct gatgctggtg
     7141 ctgctaaaga ttcattcgac gttgaattga catctgcagg cgacaaaaaa gttggcgtta
     7201 tcaaagttgt acgtgaaatc actggtcttg gtcttaaaga agctaaagaa cttgttgacg
     7261 gtgcaccagc acttgttaaa gaaggcgttg caactgcaga agctgaagaa atcaaagcta
     7321 aattggaaga agctggagct tcagttactc ttaaataata gagtatcgca atttgattgc
     7381 ggaatcccta tttaccagtc tttgagagcg ataagcgatt gatagaaact gataaattga
     7441 tttggtttcc tgccaaaaat tctttggcag gatttttgtt ttaataaact ttcgggggta
     7501 gacactagat tgtctacccc tttttttgtg tttcggaggt aattatgcaa aaggaaggac
     7561 agtcatcacg tcaattcgtg aagagtcatc tcatgactat catgggagtt gatattgtaa
     7621 aagcaactca gttagttgat gaaatggaac aagtaggttt aatccgattt gatgaatttg
     7681 gaaatgttgg aattttagtc ttggagggac aataatgaag cgtattaccg ctaatcaata
     7741 tcagacatca gagcgttatt ataagctccc caaactttta tttgagagtg aacggtataa
     7801 gaatatgaaa ctggaggtta aggtggttta ctcagtttta aaagatcggt tggagttgtc
     7861 tttgagcaaa ggttggattg atgaggatgg ggctatttat ttgatttatt ccaattcaaa
     7921 tttgatggca cttttaggct gttcaaagtc aaaattactc tccatgtgag tttgaagtga
     7981 catttttaga tgattaccat aaaaaacata actacccact attttacgaa tcctatcttc
     8041 aaaacgttat ggaattcctt gaaagtcaag acataaagaa tggggttgat gcctttgtag
     8101 atgatcatca aaatctcgtt tttgttttat atggacaagg ctatcgagcc gagggaaaag
     8161 agggaatact tacaacccaa gtaactgtaa aagcttatga tgaagacaag aaaccgatta
     8221 acttcgcaaa tttattagat tccttaattt attagattcc ttaatcgtgt cagaatatca
     8281 aatggaaccg aatctttggg aggtctccca tgattgatct ctatctaagt aaaaatagac
     8341 aaagaaatca acttctttta gatttcttcc aaaactatgg catagaggta tcttgtcatt
     8401 cagtttctga aatgacaaag gacaaattaa ttgagatgat gagctattct tcagattgtt
     8461 ttgagttttt atctcccaat ttattacgat ttaagaaccg tgacaatcta agattaacgg
     8521 atttcgttga gataatttta aaaaatcctg aactaaccat cagacttcct cttgcggttt
     8581 caaataagcg agtttatcca agtctgaatt tggaagaggc tagagctcta ttgccaagag
     8641 atacgaaaca attgatttac atggcgcaaa cacattattt atctaactaa aggagaagca
     8701 atatggctga acgattttgg gagaacttgt ccattatttt ggctgaaaga aatatcagct
     8761 ggattgagtt aaccagaaaa atgtttgcgg gagagtttca ctatccaagt gaattgaatc
     8821 gtttgtatca aaagattcgc cactagaaga tggaacaatg aatgcctcaa agtccatggg
     8881 tagaaaggat tgtgcaggta ttagatttag attatgaaga tttatttcgg aggtaactat
     8941 gaaaagaata attccagttt atatattcca acaagtaaat gtcctattgg tatctctata
     9001 cttattgaaa tttctttgta tcggtgagtt aactatacta cagattctct atggttcgtc
     9061 actcatttct tttttatgga tgtatggcca acgcaaacaa gcgcataagg tcaatatgaa
     9121 atctaggatg aaatggcttg gtgttgaatt tgttagccta ctgattataa gtctatgttt
     9181 tagtctgatt catgctcaag gaagcacgaa tcaagcaaac ttaattggcc ttcaacatca
     9241 aattccttgg ttttcatttt tattgttctt aatcaatgcg agtatggttg aagaatttct
     9301 gtatcgagaa attttatgga atttggtcag aaaattagat atcagagttg ctttgacaag
     9361 tgttttattt gccttagcac atcatacagg aaccattcta gcttggtgtt tgtatgtttc
     9421 acttgggatg tttttaggta tggtgcgcta taaatctgac ttatggggca gtatgggact
     9481 acatttggtg tggaacctac tagtttatag tttgctgctt ttttaaaata ggtgacctga
     9541 tttttaggta acttctaaaa ctaacttcca gttttgggag agagatggaa gttactttga
     9601 aaagttacgg aaacattatt ttctatgtga caacattgta taattgcttg cattttactg
     9661 gtggagagag tataatgagg gtggataaag tacttaatcc caaaaattta aataggagga
     9721 gctagctatg gcagaagaag tattaaatct tcaattagta tctgttcaag ttgacgaaac
     9781 agatgaagtt gatggaatgc gatttagtac attcagtaca aatcgttgcg gtaactggag
     9841 tgcttttagt tgggaaaatt gttaattcat ttaaattgta aactttagag attctctgga
     9901 gttatggatg tcgttccaat atgtgcacgt tggaatgtta gtgcttatat ggggagaatc
     9961 caaaggattc tcccttttta tttaaataag tctgtctagc tatagatata ttaagtttga
    10021 taaaatttct tggagatttt gttatggatt ataatttcaa tttggagcat cctttctttt
    10081 tcactaataa tgattatagt acagatacta gcataaagta ccaagtaagt ctgcctttta
    10141 attggcacga agtaatgaat aatgatgagt gggtttatca ataccctatt ggaaaatttg
    10201 ttgaaagaca agggtggaaa atacacatta gttcagagta taacagttca catgaattgt
    10261 tacaagatgt agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat cttagtacag
    10321 aagacaaatt tatcatgcga aacgggaaat tggttagtcg aggattttct ggtaaattta
    10381 ttacatgtta tccaaatcaa aatgaattag agtcggtttt gcaaaggtta gaaagtgcct
    10441 taaagcaata taatgggcca tatattttaa gcgataaacg ttgggatgaa gcaccaatat
    10501 atctgaggta tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt gctattgatg
    10561 aattaattgt tggcgatgaa gttgttaaag atgaacgttt accagtattt aaaattccaa
    10621 aaggtatagt gccccctgac tttttgaata aatggcttga caagaaagat aaaaaacagg
    10681 gagactttcc ctttattata gataatgcaa ttagattttc aaacagtggt gggatatata
    10741 atgctaggct aaaagaagat gggaaaaaaa taattttaaa agaggctaga ccgtatacag
    10801 gtctaggatt tgatggtact tattcttcag agaaattagc ttcggagtgc aaagcactaa
    10861 aaattctaaa tgaatggagt gagacgccta aaatatactg gcacggtaag atctgggagc
    10921 acaccttctt aggaattgaa catatgaagg gcgttccact aaatagatgg gttaccaata
    10981 attttccttt atatgaagtt gttgataaga ccaaagatta tctattgaga gtttcaaaga
    11041 tagtagaaaa actcatcgat ttaacgaata agtttcattc tgaaaatgta tatcatcaag
    11101 atttacattt aggaaatatc ttggttaagg atgaagatga gattagtata atagactggg
    11161 aacaggctgt cttttcaaat gatgaaaaag ttgtacataa agttgcagcc cctggtttta
    11221 gagcatggcg agaaacactt cccagtgaga tagattggta tggtattaga caaatagctc
    11281 attatttata catgccacta gtaactacat cggatttgac atacaactat gtaagtcaaa
    11341 ccaggataga aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa catatagatt
    11401 atgtagaaag tttattgtca tatctagatt ctaaatgtcc acagattgag aatatttcca
    11461 ggaaaaaagt tttaaaatcc atgcatgaga ttagaactat cgagagtgag caagatatac
    11521 aagattttat tataaaatta ttgagagggt ttacgctaac ttatggacag tggcgtaaag
    11581 aatttcaatc aagattcttc ccagttcatt attatggtct gaattttaat caaggaattg
    11641 cgttttcaga tttagctatc ctttggagtt atcaacaact agctaagaaa gtaaaaaatt
    11701 tcaagtttga tgactattat gagattcgaa cacaggttat taatgaggca gtaaataatt
    11761 ttaagaaatc gtccctttct ggtctttttg atggtaaaat tggtacaatc tggctcattt
    11821 atgaatttgg ggagatagat cgggcagttg aactttttac aactcatttt atagagatat
    11881 ttgagaattc acaaaataaa aatttatata gtggacaggc tggaatttta ctggttggac
    11941 tgtattttct tagtaaaggg gaaattgata ataaactagg agaagaaata ctaattaggc
    12001 ttagagaata tactttaaat tatatagaaa atccagaaac tttttgtaaa gttggcgcta
    12061 gtgatgttca gagtaatgat ccttatgaga attttggtgg attactatat ggtcacgcag
    12121 gggtagcttg gctcttcggt gaagcttata aattaactgg tgaaagtatc tataaaaatg
    12181 gtctagaatt ggctgtagat aaagaattag ttgcttataa agtagatagt aataattcat
    12241 tgcagtacag ccaaggtcat agattactac catatctagc aactggaagt gctggcctgc
    12301 ttttacttat taatagaaat aaagaaatct tgtcaagcaa atacttaaaa tatttaactt
    12361 ctttagagag ggcaactgat gtagtttttt gtgtattacc aggtttattt aacggatttt
    12421 gtggtcttga agttgctaat aatatatata gtgatatcga tgataacttt tcaggacaaa
    12481 agaaattaat tgaacaactt tatagatatt tgtgtgtaat tgaagaagga tttgttattg
    12541 cgggagataa tggtttaaag ataacaacag atattgcttc gggatttgcg ggtgttgcaa
    12601 ttggattggt atcaataatg gataataaat tgacgattct tcctcaaata taatatttag
    12661 ataccattat taaggggtca tacttgtgaa tcagagtaat gaaatatttt taaatacaat
    12721 acaggaaaaa acacactata agaggtctat ctcttcatca tttcaggaat taaaaaaatg
    12781 gaattctttg atatttagga gagggcgata ttggtaccaa tttgataatt ggagtatacc
    12841 caatactggt gtaataaagg aatggtatgt cgaagataat gactggattc ctaaggttag
    12901 ttcttccagt ttagacaatt caaattcact taaaattgtc tttgatgtgg aaaaatatac
    12961 tttgccagat gatagtatct tacaggatgt taggatttca tctgatgaga gttatatagt
    13021 tttggttgta tcctcactgc gtagcactaa tttaattgga ataaaaaaat atactatgga
    13081 agagttattt atcattgaag atatttcagt agaaagttcg ttctatttgg gtaaattcgg
    13141 tgttatgtat actcgctcca aagagtacgg gaggccaagt aagttattct ataaatcttt
    13201 tgatagcttt acagaagagg aactgtttga agaaaacgaa tgctcttttc gattaaaaat
    13261 agtccacatt gatagcaata attgttttgt aaagtcagta gactttcaga aaggcaggat
    13321 ttttctatac agtttcgacc ggacgggttt tgttagacac tcttacacag aaacggtagc
    13381 cccaacacct agagatatcg ctctatttag tacagaaaaa gcacagtact ttcttgggat
    13441 ctcttcaact gaagaaaaga aagatcaact aattctaagg gaaacttctt cgggagacag
    13501 agtttctatt actataccat atcaagatag ggctagaaga gttcactgta taggacgtta
    13561 tatcctttta gactgttcaa acgcagcgaa ttccgtcttt tatcttgcta catttaaaaa
    13621 taatagtttg agggagttga gtgttaataa gataacattt gatgaaaaga caacacttta
    13681 tgaaaattca ttttctgatc gtgttcttct gtttttagag aggagaactt tttacgaaaa
    13741 aatacttagt tttgatttaa tagaaaatac attaaaaact gaatttgaaa gacccatcat
    13801 aaaatcgaat aatactaaat atttttctaa ggtgatttgg actaaaaaag acagttatga
    13861 tgtaagcata ccgatttctt tattttggaa aagtgaagat acggatgagc tcccaagaag
    13921 aaaaaaatgt attctaagtg tctatggggc ttatggtaag aatgataatt ctgatttaga
    13981 tgaaattatg ttatctataa tagatgcagg ttttatttat gctatagttc atgtaagagg
    14041 tggaggctat ttgggtggtg aatggtatcg ctcaggaaag gcgttaaaca aatggaattc
    14101 tatcagagat tttattgagg gagtaaatta tttaagggaa aatgatgtaa ttgacagtaa
    14161 gcgattaggt ttaataactt ctagtgcagg tggaataatt gctggtgcgg tgttgaacga
    14221 ggaaaaaaat ttattgcaaa gcattctctt attttcgcca tttataaatc cttatgatac
    14281 acttcagaat ccaaatgatc ctctttctaa gaccgaaata gcagagtggg gagatattag
    14341 agcccctgaa gtaaaggctt atataaagtc atattcgcct atgcaaaata ttgaaaaggc
    14401 acgagactca aatactgtta tagttaatat tttgggtgag aaagacccat atattaataa
    14461 taacgaagtg atagagtggt caaagaaatt aaattctatt ggagttaaaa gtttgttgta
    14521 tttaaacaaa gcagctgatc atggaggttt tactccatca gatgttctct taatgattga
    14581 tactttaaat tatttctttg aagaagtggg aaggaataac ttatgaatta tttaaaattt
    14641 ataaaaaaga ctaaacttat attaatgggg attttaatat ttctatcttc gtttaatggt
    14701 gtcttgctct caggaattat tgtatatgca ggtagtttaa atcagacttc ctcattttct
    14761 gacgttctaa gatttggtgc tataagtatt ctgggttggt cagcaatcta tatatcaaat
    14821 tactatttag aagtaacgga agcatcaata acgaaagata taaatgtaaa aattaaacaa
    14881 ggatatttta gagaacagta tctttcttct gaaatggtta aagattactc atctattatt
    14941 tcagttttgt caaatgattt gagattaatc gaagaaaact attttagaca aatttttgaa
    15001 ataatttctt caatattgt
//
LOCUS       DAVLAQ010000042        14667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000042 DAVLAQ010000000
VERSION     DAVLAQ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.042"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            77..265
                     /locus_tag="VXB71_001453"
     CDS             77..265
                     /locus_tag="VXB71_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451551.1"
                     /translation="MSFFAGFGAKLEFTSYNPFLSVKFGLVVALTVFVVQLLAILPAM
                     VKRGNKNENVESNNSCEE"
     gene            228..1619
                     /locus_tag="VXB71_001454"
     CDS             228..1619
                     /locus_tag="VXB71_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV0451552.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNIKIVRLFIQIFVFLLLISSWIA
                     IIPFIARLVFSMFFISLLFFVEKFFRSNFIAKLRNKLNIREALFYMLISLNLYDELDN
                     EVVDTAVLYFDVENNKVVVCAPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKIV
                     YVLGQKEEIEQYVFNSNTLTREFFKDIPSSIIKLSNTQKFSLKSNTNLGIYGRTGTGK
                     TIALQWYLFNALAKGCGIADNTYLGIVDGKAADLYRIGELLHEELGEQVAVGSSPQML
                     AQLSRKFIENMDARFKIIKQNSSLNADIYELDELGLVPNFLFVDELASIRDSCGSTKQ
                     GRETWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGAPGAD
                     RLKMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKKEFLNVVRN
                     ILPTNDGLPPLAK"
     gene            1875..2294
                     /locus_tag="VXB71_001455"
     CDS             1875..2294
                     /locus_tag="VXB71_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451553.1"
                     /translation="MVYNMTDTNIKIGLLDLEMSQFDIPKKVVILSVRVNNKYKEVNG
                     ENVKTDEVSKITSAVLDADKVKVLTEMGISTDDLKAINLEIIGNLDKIAKLAQNDALL
                     NVPVELIRPKVRLAWNMARNNWSGVKIVCEDIKVLGE"
     gene            2299..3318
                     /locus_tag="VXB71_001456"
     CDS             2299..3318
                     /locus_tag="VXB71_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV0451554.1"
                     /translation="MNTVRIDYFAVTVKNISPEKVLTDILLIPLENFTLNDWGINKYK
                     QHYSCSEIKVYFNADRLSMGVFIELKGQGCRQYEEFLNSNENNWIALISRLYHHNANF
                     TRLDIAHDIFDGSLDVQRIYDYCKKGLCISKAKHFEYHEKSVLDSGERVGETVAIGSR
                     GNQQWCIYNKRMEQLGKQELVEVSSWTRAELRCWQEKANIIAEQLYLKRPLSSIYFEA
                     INGHYRFIRPNAIDSNRWRRKKVEWWVNYLGTENQTVLSITRAKTTLRESEVWTEKQV
                     AKTLAKVYIAKYQAYDVQKAEDYIQNLLKEGLSKLTDNDEKDIEQYIREQNSSQLWGT
                     DGRSD"
     gene            3322..3504
                     /locus_tag="VXB71_001457"
     CDS             3322..3504
                     /locus_tag="VXB71_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV0451555.1"
                     /translation="MADTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            3506..4633
                     /locus_tag="VXB71_001458"
     CDS             3506..4633
                     /locus_tag="VXB71_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0451556.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(4716..4788)
                     /locus_tag="VXB71_001459"
     tRNA            complement(4716..4788)
                     /locus_tag="VXB71_001459"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4753..4755),aa:Lys,seq:ctt)
     gene            complement(5053..6324)
                     /locus_tag="VXB71_001460"
     CDS             complement(5053..6324)
                     /locus_tag="VXB71_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0451557.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            6594..6794
                     /locus_tag="VXB71_001461"
     CDS             6594..6794
                     /locus_tag="VXB71_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451558.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            6998..7177
                     /locus_tag="VXB71_001462"
     CDS             6998..7177
                     /locus_tag="VXB71_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451559.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            7314..7493
                     /locus_tag="VXB71_001463"
     CDS             7314..7493
                     /locus_tag="VXB71_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0451560.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            7530..7982
                     /locus_tag="VXB71_001464"
     CDS             7530..7982
                     /locus_tag="VXB71_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0451561.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            8273..8743
                     /locus_tag="VXB71_001465"
     CDS             8273..8743
                     /locus_tag="VXB71_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0451562.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            8762..9850
                     /locus_tag="VXB71_001466"
     CDS             8762..9850
                     /locus_tag="VXB71_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0451563.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            9831..10259
                     /locus_tag="VXB71_001467"
     CDS             9831..10259
                     /locus_tag="VXB71_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0451564.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            10397..11347
                     /locus_tag="VXB71_001468"
     CDS             10397..11347
                     /locus_tag="VXB71_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0451565.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            11349..12092
                     /locus_tag="VXB71_001469"
     CDS             11349..12092
                     /locus_tag="VXB71_001469"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0451566.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            12103..13899
                     /gene="pepF"
                     /locus_tag="VXB71_001470"
     CDS             12103..13899
                     /gene="pepF"
                     /locus_tag="VXB71_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0451567.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(13959..14636)
                     /locus_tag="VXB71_001471"
     CDS             complement(13959..14636)
                     /locus_tag="VXB71_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451568.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQKKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
BASE COUNT         4463 a         2512 c         3377 g         4315 t
ORIGIN      
        1 atttgaaagg aaaaatacaa aaatgaaaat taatgaatat ttatggagaa cgagctgtct
       61 tatactgcta attatcatga gcttctttgc aggcttcgga gctaaattag agtttacatc
      121 ttataacccg tttttatctg ttaaatttgg tttggtcgta gctctgacag tctttgtagt
      181 tcaattgtta gccatactgc cagccatggt taaaagagga aataaaaatg agaatgttga
      241 atcaaacaat tcgtgtgaag agtaaatacc cttacttgat tcgtccccga aatattaaaa
      301 ttgtaagatt gtttatccaa atttttgtct ttttactctt aatatcttcg tggattgcta
      361 taatcccatt tattgctcgt ctagtctttt ccatgttttt tataagtctt ctttttttcg
      421 tagagaagtt ctttcgttct aattttatag caaaattgag aaacaagctc aatatcagag
      481 aagccttgtt ttacatgtta attagtttaa atttatatga tgagctcgat aatgaagtag
      541 tagatacagc agttttatat tttgacgttg agaataataa agttgttgtc tgtgccccac
      601 tatttgggaa ccgttatctg aaaaccttga aaaatttaga ggaatatctc tgtcccactt
      661 tgggcttgtc cttgctgtct aaaaaagaag aaatcgataa aatagtatac gtgttagggc
      721 agaaagaaga aatagaacaa tatgttttta atagtaacac attaacaaga gaatttttta
      781 aagatattcc tagttcaata atcaagctgt caaatacaca gaaatttagt ctaaagtcca
      841 acactaacct aggtatatat ggaagaacgg ggacaggcaa aacaatagct ctgcaatggt
      901 acttatttaa cgcactggct aaaggttgtg gtattgctga taatacttat ttaggcatag
      961 tagatggtaa ggcagctgac ttgtatcgta ttggtgaact tcttcacgaa gaactgggag
     1021 aacaagtggc agtaggctct tcaccacaaa tgcttgccca attatcgaga aaattcattg
     1081 agaatatgga tgcaagattt aaaattatca aacagaatag ttcattgaat gctgacattt
     1141 atgagctaga tgagctggga ctggtaccta attttttgtt cgttgatgaa ctcgcttcta
     1201 ttcgtgatag ttgtggctct acgaaacaag gtagagaaac atggaatgaa attctacaaa
     1261 atttaggctt gattgcacgc aaaggacggc aggcaggttg ccacctagtc ctatctactc
     1321 aagaccctaa tgccgaaaac atccccgttg aattgaggaa tcaaatttca gcagttttat
     1381 accttggtgc cccaggggct gatagattga agatggcttt tagcatgtgc gaattagaaa
     1441 acgttcctac agtttcagat agaaaagggg aggctctctt ttatgctgat gggcttaata
     1501 cagtagagcc agtgctaaca attgtgccat ttgttgattt aaaaactaag aaagagtttt
     1561 taaatgtagt tagaaacata ctgccaacta atgacggtct tcctccccta gcgaaatagg
     1621 gcgattgccg gaggcagaat cgagcggagc gctctctttt cgctagggga gggagagcca
     1681 accgactgct ttgcaggagg tcagaaaaaa catccccagt actaataggg ggtgcacaca
     1741 tacatgaaat gtactctaaa cccttgatac gtgaggggtt acggcttact agttgcacca
     1801 aggggtcgca aactcttggg agagtaggga tgagaggtgt ttccatgtat gatacggaat
     1861 taaaggagaa aaatatggtt tacaatatga cagatacaaa cattaaaatt ggattgcttg
     1921 accttgagat gtcacagttt gatattccta agaaagtagt gattttatca gttagggtga
     1981 acaataaata caaagaagtc aacggcgaaa acgtgaagac agatgaagta agtaaaatta
     2041 cttctgctgt tcttgacgct gacaaagtga aagttctaac tgaaatggga atttctactg
     2101 atgacttaaa agctattaac ctagaaatta tcggaaatct agataagatt gcaaaacttg
     2161 ctcaaaatga tgctttgttg aatgttcctg ttgaattgat tcggcctaaa gttcgactag
     2221 cttggaacat ggctaggaat aattggtctg gtgtaaaaat tgtgtgtgag gatattaaag
     2281 ttctaggaga ataatcctat gaatacagtt agaatagatt attttgctgt gacagttaag
     2341 aatatttcgc cagaaaaagt tctgacagac atccttttga ttcctcttga aaactttacc
     2401 ttgaatgatt ggggcataaa taagtataag caacattatt cttgttcaga aattaaggtg
     2461 tattttaatg ctgataggct ttctatgggt gtatttattg aattaaaagg gcaaggttgt
     2521 cgtcaatatg aagaattttt aaacagtaac gaaaataatt ggattgcttt gataagtcgt
     2581 ttatatcatc ataatgccaa ctttactaga ctagatattg cccacgacat atttgacggt
     2641 agcttagatg ttcaacgaat atatgactat tgcaagaaag gattatgtat ctcgaaagca
     2701 aaacactttg aatatcatga gaaatcagtt ctagattctg gtgagcgtgt aggagaaaca
     2761 gttgcaatag gttcacgagg taatcagcag tggtgcatat ataataaacg catggagcaa
     2821 cttggtaagc aagagcttgt agaagtttca tcttggactc gcgcagagct tagatgttgg
     2881 caggagaagg ctaatataat tgcagagcag ttatatttaa aacgtccctt atcgtcaata
     2941 tattttgagg ctatcaacgg tcattatcgc tttattcgtc caaatgctat agatagtaat
     3001 cgttggagaa gaaaaaaggt tgagtggtgg gtaaactatc tagggacaga aaatcagaca
     3061 gttctgagta ttacaagggc taagacgacg ttacgggagt ctgaagtttg gactgagaaa
     3121 caggttgcaa aaacattagc aaaagtctat attgcaaagt atcaggccta tgatgttcaa
     3181 aaggcggaag attatattca aaacttgctc aaagagggac tttcaaagct aactgataat
     3241 gatgaaaagg atatagaaca atatataaga gaacagaata gttcccaact ttggggaacc
     3301 gatggaagga gtgactgaca tatggcagat actatatcaa ataaggattt gatttccatg
     3361 ggctataggc catcaacagc taatgctatt atccatcagg cgagagaatt acttgtatca
     3421 cgaggctata cattttataa tcgcaaacgt ttgatggttg ttccaaaaag tgttgtgaaa
     3481 gagttgttgg gaatggaatt gtgaaatggc ttatatcgag tataaacagc gtggtaagaa
     3541 aagactttgg tccttctcta tacgagaaag gagcaagagc ctactccata aaagcggatt
     3601 taaaacaaaa cgagaagcta aaatagaagc ggagaaagtt cttcataagt taaatactgg
     3661 gagtgtctta agctctagta tgactttatc ggagctttat aatgaatggc ttgatttaaa
     3721 aattttacct agcaatagaa gtgtagttac taaaaaaaaa tatctcatga gaaagaaggt
     3781 catcgaaagg ttatttggaa ataagcctgt atcacaaatt aagcctagcg agtatcaaaa
     3841 aattatgaat gagtatggag agactgtatc gagaaatttc ttaggaagat tgaattcttg
     3901 tattcgggca agtatacaga tggctattgc tgataaggtg ataatagagg attttactgc
     3961 ttatgttgag ttgttctctt ctaagagtgg acaaaaggtt gaggaaaagt atttgcatgc
     4021 tgagtcagat tatcaaaaag ttttagtata tttgaaaaat aagtttgatt atcaaaaatc
     4081 tattgtaccg tatgtaattt atttcctttt taaaactggc atgcgtttct ccgaattgat
     4141 tgctctaact tgggatgaag ttgacgagct taatgagcaa cttaaaactt atcgtcgtta
     4201 caacaccgct attcataagt ttactccacc taaaaacaat acttcaataa gattagttcc
     4261 tattacttca gatatgcttt ccttgttaaa aacattgaaa atattgcaat taaaaacaaa
     4321 taaagaatta aatattgata atgaaaataa tttgattttt cagcattttg gctatgtcta
     4381 cgatgttcca gatattgcaa cagtcaataa agctataaaa gtaatgttga aggaattgca
     4441 aatttttcca ttgattacta ccaaaggagc tagacacact tatggtagtt atttatggca
     4501 taataatatt gatttgggag ttatagcgaa aattttagga cataaagata tctccatgtt
     4561 gattgacgtt tatgggcata ccttggagga aaaaattagt gaagagttta tggctgtgaa
     4621 aagtttgttg taaaaacacg gcaaattgca cgacaatttt taaaaggaag gcaaaaaaag
     4681 ccctatatta taaggctttt cctgttgtat ttatatgccc cctacaggga tcgaacctgt
     4741 gacccacgga ttaagagtcc gctgctctgc cagctgagct aaggaggcaa agaaaaaagc
     4801 tgtattggtg ccgaaacttc acggtttgta ttgaacccgc gcaattaagc aggtgggcaa
     4861 ctcgctctaa ctgaagctgt ttccgtgtga gacggcctac atgctgttag aagacttttg
     4921 tttccctaat aatacaaaaa atagtcggtc aacacttaag tgtgaagtcg tacaccacag
     4981 cgtttctata cttatatgat accacttttt caaaaaaaat caagaggaaa gtgcaatttt
     5041 ttgaaaagga tttcagattt ttcgcaaacg gtcgatagct tcctttcttt gagccaaagc
     5101 ccgttcatat ttaccagtat cttctgcttg gaaatagtga tgattacgaa ttttttctgg
     5161 cagatagtct tgcttgaccc aatttccagg atagttgtgt ggatagagat agtcttgggc
     5221 attccccagt tccttgcttc cactgtagtg cccatcacgt aggtgtcgcg gaataggcaa
     5281 gtgccctgat gttttgaggt cagcaagtgc cttatccata gctacatagg ctgagttgga
     5341 ttttggagaa agggccaaat caatcacgac attggcaatg agaatgcggg cttctgggaa
     5401 cccaatcttc tgggcagcat ccagagcagt cacggtatga atctgggcct caggattggc
     5461 taagccgata tcttcatagg cgataacagt caagcgacga gcgagactag gcagatcccc
     5521 agcctcaatc aagcgggcag tatagtggag actggcatcc acatctgagc cacgaataga
     5581 cttttgcagg gcagatagaa catcatagtg accgtctcca tccttgtcca tagtgatgta
     5641 gcttctctga agactatttt ccatgatgtc taaggtgatg tggcgaatgc cctcgtcatt
     5701 ctcaggggta gagagaacag ctaagtccag tgagttaaag gcagagcgaa ggtctccgtt
     5761 tgtagaggtt gcgatgaaat ccagcgcatc ctcatctagt tctattggaa aatcaaaacc
     5821 acgttcaggg ttacttagag ctatctgcag ggcctctttg acgtcttggt tagacagagg
     5881 ttccaactcg aaaatttgaa ctcggctacg aatggcagga gtgacagaga agaaaggatt
     5941 ttcagtcgtt gctccaatca tgatgaccag tccactttcc aagagaggca agaggaagtc
     6001 ttgcttggtc ttatctagtc gatgaatttc gtctagcaat aggacgagac caccagaaaa
     6061 tttagcttct tccgagattt cttgcagtcg ctttttacta tcaactgtcg cattgaaagt
     6121 tcgaaaggca tacttggtcg ttccagcgat ggcagaggca atactggttt tgccgattcc
     6181 aggagggcca tatagaatca tggaggacag gcggttggct tccaccatgc ggcggatgat
     6241 ttttccaggt ccgaccagat gctcctgacc gatgacctgg tcgatggttt tagggcgcat
     6301 gcgaagcgcg agattgtctg gcatagcagt cctttctagc gtggatttga gtagaatgac
     6361 tcatctacta tatcttacta tgtccattct agcctattag ttgtgatatt tcaatggttt
     6421 tgtaataatc agggagtgag atagaatctt ttttactatt taatttaatg aggagaggta
     6481 tcagcatgag agatttgatt ttccttaaag ctcaaaatag gatagttgag cctaaagaag
     6541 tggaagtgct gacttgagaa ataatattgc tgaatgtcat tgtatgaact ataatgaaaa
     6601 gagaggtgat aagcaatgga aatgatggac caagtcagga aattttgatt tttacaaaac
     6661 aaattcgtca ttggattctt agtgatcaag ttatttcagg gaaaagaaaa cttttcttcc
     6721 gggaagatac tccaaaagag attttagatt tgtacgaaaa cattaaatct aaacttgatt
     6781 ttgcttacca ataagtttat tctaataatg ggttgaaaaa atatgaaaaa tagaataatt
     6841 gatgtttttg aagtagtaaa tcgcatcctt gtaataactg ttgaaaatcc tgatttcgaa
     6901 gacttgagag ttaatcatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
     6961 gctgtacttg agtacggtaa ggcgacgttg acgtggtttg aatttgattt tcgaagagta
     7021 tcagtttgta aaaattggag ataaaaaata tagagtacgc agtgttccta tgattcattc
     7081 aactccgcct caatctgtct tagatcgaga tacttttaca attgactata cagatgatga
     7141 attgctcgat aaagaagcag tttttactac tcattagaaa aataggtctg aataaattgg
     7201 cttcccttag aaccacatct aggggctttt atgtataata gaataataag tatcactcct
     7261 ttacaatacg tgtaacacgt gttataatgg tgttgtcagg aggtaaaagc gctatgccta
     7321 tgacacaaaa agagatggtt aaactcctta cggcccatgg ttggataaag actagaggcg
     7381 gtaaaggctc ccatattaaa atggagaagc aaggggaaag acttatcaca atccctcatg
     7441 gtgagctgaa taagtacact gaaagaggga taagaaagca agctgggttg taaaattcag
     7501 cccctgtttt ttgatatgga ggtagtgaaa tgttagttac gtatccagct ttattttatt
     7561 atgacgacac agacggaaca gaagcgactt attttgtcca tttcccagat tttgaatact
     7621 cagctacaca aggagagggg atttctgagg ctttggctat ggggtcggag tggctaggga
     7681 taactgttgc agatttgata gagagtgatg gagagttacc tcagccatca gatatcaata
     7741 gcttgtcttt aattgataat gatcctttta aagatgatga agatttcgtg tcaacctatg
     7801 accttgataa atcttttatt tctatggtat ctgttgatgt atcagaatac ctaggaagtc
     7861 aggaacccat aaaaaagact ttgaccatac caaaatgggc agataagttg ggacgagaaa
     7921 tgggacttaa cttttctcag actttgacag acgctattgc agataagaaa gttcaagcct
     7981 aagattaagc gtggtatcgt ggtaatagtc aataaaaaag cacgtccact tgtgctagtt
     8041 actcgcctat tgattttata gatttattag ccctttcgcg ggctttttat attgattttt
     8101 atgagaaatg aagaaatcag acttttaaga aaatcactga taccaagggt ttaaatgagg
     8161 taatatggta taattaggac ataaaataat tttgtggtaa gatggtagta tctattttag
     8221 catatttccg agcaatcggg gcgattaaag agtcgcatag aaagaggaca aaatggcaac
     8281 atacggattt ttagatgttt tagaggaaga gttggacaag aactttccct ttgactttga
     8341 gattagctgg gacaaacgca accatgcggt agaagtgagt tttctattgg aagcgcaaaa
     8401 tgctgcaggt gtggagatgg tggatgaaga cggagaggtt ttatcagatg acattctttt
     8461 tgaggaagcg gtccttttct acaatcctgc caagtcaaca gtcaatgagg aagactattt
     8521 gactgttatt ccttacctgc ctaaaaaagg attttcccgt gaatttttag cttattttgc
     8581 gcttttcctt aaagatactg ctgaggttgg gctagatgtc ctcatggact ttttggaaga
     8641 cccagaagca gaggaatttg tcatggaatg gaaccaagaa gtctttgaag aaggaaaagt
     8701 tggcttggaa gagggagaat tttatcctta tccaagatac taggagttgg ttggaggtgt
     8761 tatgaagaaa attgggactt atttggttta tgtgctagct tttgtcttta ttatgctagc
     8821 ttttgcttgt ggaacaatcg catttgcaga gttggggtat tccgcagttt tagcctttac
     8881 ttttggttat gccttcgctc ttctaagcat gtatttaatc tttattcttc atgagctggg
     8941 tcatgctttt tgtggctact tgacaggcta tcggctggtg gcttttggat taggacattt
     9001 tattttgacc aaaaagtcag gcaggtttca tcttagtaga acagccattc tgaaaaatgt
     9061 tggtgctcaa tacattggtt taaaagagga tgaaagcgat caaagaatca tcctgatgct
     9121 ttcaggaggc ttgatggttc atctcggctt gatattattg gcgatagtgt ttggattttt
     9181 gacaagaagc tggtattttg cagggacttg gatttttctt aatttatctt tcttcctaaa
     9241 taacattttg ccagtcgaca tcaccgatgg agcaaaaatt tgggaattac tacaacaccc
     9301 tgaaaatacc aaatacgcct acctggtatt gagacattct gctcaaactt tgctggctcc
     9361 tcaagaatat gatttgaaag actttgttca agcagttcct gaggatgcac gagggagttt
     9421 tgcggatggt gtattaggta tgcaaggtga agtttccatt ttggaaggga aggaagaagt
     9481 agctaaacag cagtttcaag cattacttga gaggacaact actccgatga tgcagacagt
     9541 tgcccaacta tccctgcttc atatcgcctt gttggaagga gattttgagc aagcggagca
     9601 atatgctagt attcgacagg tcaaatcgtt tctgtctctc aaactgtcca atcttcaagt
     9661 gatacaagct tggtatcaat ttaaggtaaa gaaagatgta gatcgaactc gtaaggctct
     9721 caagattgct agacagaaaa tggatagtag tcgaatgttg agggacgaga aacgctatta
     9781 tgaaaacttg ttagcagagc tggaaaagga aatgttagaa ggaactgaag atggaactag
     9841 aaatttctga tttcccaggc tgtaagattg ctttgttttg tggggataag ctcttgacta
     9901 tcttacgtga tgataaggca agtattccct gggccaatat gtgggaactg ccaggtggtg
     9961 gacgtgaagg tgatgaaagt ccttttgagt gtgtagcgcg tgaagtttat gaagaactgg
    10021 gcattcatct gactgaagat tgtctgcttt ggagtaaggt ttacccaagt atgctttttg
    10081 cagacaaaca gtccgttttt ctagttggtc agttgacaca gaaccagttt gacagtatcg
    10141 tatttggaga tgaaggacag ggctatcagc tgatgaatgt tgaggaattt cttagttcca
    10201 gtcaagttgt ccctcagttg caagagagat taaaagatta tttaaaagta agtgattaga
    10261 aaggatggtt cagttaaatt tctaaactga acccgcccta aacactgtgc caaaaagata
    10321 aacttctctt agacacaagc gtcttcagag aatttcctat tttggttttg tgttttacgg
    10381 gcttggtatc ttaataatgg aaacatggca agagttaaaa gttacagtga agcgtgaggg
    10441 agaggagttg gtttccaatc tcttgattga gctgggagcg caaggagtcg caatcgaaga
    10501 cagtatggac tatgtgggaa atgttgaccg ctttggcgag attttcccag aggtggagca
    10561 gcaagaagaa atcgttgtga cagcctacta ccctgacacg gtggatgtga cagtggttga
    10621 ggcggacttg caggctcgca tatcagaatt gacggatttt atggatttgg gagagttaaa
    10681 aataggtacg actgccttgg ctgaggaaga ctgggcagac aactggaaga aatactatga
    10741 gccagctcgt atcactcatg atttgaccat cgttccctct tggacagact atgaggcgac
    10801 tgcgggagaa aaaattatca agctggatcc tggcatggct tttggtactg gaacccaccc
    10861 aactaccaag atgagccttt ttgccttgga acaggttctt cgtggtggcg aaacggtgct
    10921 agatgtgggg actggttcag gggttctctc tattgccagc tcgcttctgg gggctaaaga
    10981 aattttcgcc tatgacctgg atgatgtggc ggttcgtgtg gctcaggaaa atattgagct
    11041 caaccctggc atggaaaata tccatgtagc ggctggagat ttgcttaagg gtgtggaaat
    11101 tgaggcagat gtgattgtgg ctaatatctt ggcggatatc ctcattcatc taatagacga
    11161 tgcctatcgt ttggttaagg acgaaggcta cctgatcatg agtggcatta tcaaggacaa
    11221 gtgggacatg gtgcgccagt cggctgagtc agctggattt ttcctcgaaa ctcacatggt
    11281 tcaaggggaa tggaatacct gtgtctttaa gaaaaccaag gatatctctg gtgtgattgg
    11341 aggctagcat gcagcagtat tttgtaaaag gcagtgctat ctctcctgtc actatcgagg
    11401 acaaggaaac cagtaagcat atgtttcagg ttatgcgctt gaaagaagag gatgaggtta
    11461 ccttagtctt tgatgatggc atcaagcgct tggcgcgcgt gctggatatg gaaaatcgtc
    11521 agtttgagtt ggtccaagaa ttaaatgaca atgtggaact accagtccaa gtgaccatcg
    11581 catctggatt tcccaaggga gacaagctgg agttcatcgc tcaaaaagta accgaactgg
    11641 gtgctagcca aatctgggcc tttcctgcag actggtcagt tgccaagtgg gatggcaaga
    11701 aattgggtaa aaaagttgaa aaactagaaa aaattgccct tggagcagcc gagcaaagca
    11761 agcgtaatat tgtaccaagt attaaacttt tcgagaaaaa agcagatttt ctagctcagc
    11821 tggaccagtt tgactttatc atagtagcct atgaagaatc agctaaagaa ggagaagccg
    11881 ctgcgcttct gcaagcagtc actggtcttg aaacaggagc caaactgctc tttatctttg
    11941 gtccagaagg cggtctctca cctgcagaaa tcgaaagttt tgaagctaag ggagccgttt
    12001 tggtaggcct aggtcctcgt attttgcgag cagaaacagc accgctttac gccttatcag
    12061 cccttagtgt tttagtagaa ttagagaaat aagaggaaga aaatggaaca aaaacaccgt
    12121 tcagaatttc cagagaagga actctgggac ttaacagccc tataccaaga ccgtgaggat
    12181 ttcttgcgtg caatcgagaa agctcgtgaa gacatcaacc agtttagccg tgattacaag
    12241 ggcaatcttc acacttttga ggatttcgag aaggcctttg cggaattaga acagatctac
    12301 attcagatga gccatattgg caactatgct tttatgcctc agacgacgga ctatagcaat
    12361 gacgaatttg ccaatattgc ccaagctggg atggaatttg aaacagatgc cagcgtagcc
    12421 ttgaccttct ttgacgatgc cttggtggta gcagacgagg aagtcttgga ccgtttgggt
    12481 gaattgcctc acttgacggc agctattcgt caggccaaaa tcaaaaaagc ccactatcta
    12541 ggggctgatg tggagaaggc cttgaccaat ctcggtgaag ttttctatag tccgcaggac
    12601 atttatacta agatgcgagc tggggatttt gaaatggctg actttgaagc ccatggcaag
    12661 acctataaaa acagctttgt cacctatgag aatttctacc aaaatcacga ggatgctgag
    12721 gttcgtgaga aatccttccg ttccttctca gagggacttc gtaagcacca aaatacggct
    12781 gcagcagcct atctggctca ggtcaagtct gaaaaactct tggctgatat gaagggatac
    12841 gactctgtat ttgattatct tctagctgaa caagaagtgg accgtgtcat gtttgaccgc
    12901 cagattgacc tcatcatgaa ggactttgca ccagtcgctc agagatacct caagcatgtt
    12961 gccaaggtaa atggtcttga aaagatgacc tttgcagact ggaaattgga cttggacagc
    13021 gccctgaatc ctgaagtgac tattgacgat gcctatgatt tggtcatgaa gtcggtagaa
    13081 cctttggggc aagaatattg tcaggaagtt gctcgttacc aagaagagcg ctgggtggac
    13141 tttgctgcta acagtggcaa ggattccggt ggttatgcgg cggacccata tcgcgtacac
    13201 ccttatgtac tcatgagctg gacaggccgt ttgagcgatg tctatacctt gattcatgaa
    13261 atcgggcatt ctggtcaatt catcttttca gacaatcacc aaagctattt caacgcccac
    13321 atgtcgacct attatgttga agcaccgtca accttcaatg aattgctact cagtgattac
    13381 ttagagaacc agtctaatga cccacgtcaa aaacgcttcg ctctggctca tcgcttgaca
    13441 gacacctact tccataactt tatcacccac ctcttggaag ccgccttcca gcgtaaggtg
    13501 tatacattga ttgaagaagg ggagaccttt ggagcaagca aactcaacag cattatgaag
    13561 gaagttttga cagatttttg gggcgatgcc attgaaatcg acgacgatgc agctttgact
    13621 tggatgcgcc aagctcacta ctatatgggc ttgtatagtt acacttactc tgctggtctt
    13681 gtcatctcga cagctggtta ccttcatctt aaaaactcag aaactggagc tgaagactgg
    13741 ctcaatctcc tcaaatcagg tggtagcaag acaccacttg agtcagccat gattatcggt
    13801 gctgatattt caacagacaa accactccgt gataccatcc aattcttgtc tgacacagtt
    13861 gaccagatta tcgcctacag tgctgagttg ggggagtaag gggatagaga ggttgttata
    13921 gaatgggtat ggacagttat ttgcttaaaa gtccatgttt aaatccccca ttccttttcg
    13981 aggaattctt tgccctgctc tgtaatggta agtgaacgtg gcgtttgtgc agggatgacc
    14041 aattgttttt cactgaaaaa ttctaaaaga gcattgccga gagctccgcc gacatgattt
    14101 ttacgttcgc tccaatccaa acatttaggg caaaatttcc gttttttctt tttcaattca
    14161 tccgtatcaa tgtgtaattt tttttggaaa taagacttcc cagcttcagt gagttggaag
    14221 tctttttctg attcgctgag gagattttct tgcaagagat aattggtaat ggaaatgcca
    14281 agctcaccag caatatggtc atagcaggtg cgagcgacct ttaattcctt tttgtgaatg
    14341 tgttgtttat aacttttgac atcacgctga ggagagtaga agctgagaaa ttccagcatt
    14401 tctgcaatgg cagcactttt taaagaataa taatgaaaac gtccataggt ttgtagagtg
    14461 gttacctgcg cttcggtaag taatttgagg tgatagctga cagtatgttg cttgattttg
    14521 gtaaagctgg caatttcgtt aaccgtgtga gcttttccat ccattagaat atctaaaatg
    14581 tgcatccgag aagggtctga taagagtttt gtgatgatga aaatatctgg ttccataaaa
    14641 attttctcca aatttcatat atcgatt
//
LOCUS       DAVLAQ010000043        14639 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000043 DAVLAQ010000000
VERSION     DAVLAQ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.043"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(156..296)
                     /locus_tag="VXB71_001472"
     CDS             complement(156..296)
                     /locus_tag="VXB71_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451569.1"
                     /translation="MLFYLTKELNSGVKKIGTISTTLVVVAGVSAGVLGGKFDFKFPK
                     KI"
     gene            complement(250..753)
                     /locus_tag="VXB71_001473"
                     /pseudo
     CDS             complement(250..753)
                     /locus_tag="VXB71_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370715.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
     gene            complement(970..1859)
                     /locus_tag="VXB71_001474"
                     /pseudo
     CDS             complement(970..1859)
                     /locus_tag="VXB71_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1989..3086)
                     /locus_tag="VXB71_001475"
     CDS             complement(1989..3086)
                     /locus_tag="VXB71_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0451570.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNLSIAQQNFGRVPIRIETN"
     gene            complement(3096..3836)
                     /locus_tag="VXB71_001476"
     CDS             complement(3096..3836)
                     /locus_tag="VXB71_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0451571.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(4156..4509)
                     /gene="rsfS"
                     /locus_tag="VXB71_001477"
     CDS             complement(4156..4509)
                     /gene="rsfS"
                     /locus_tag="VXB71_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0451572.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(4522..5022)
                     /locus_tag="VXB71_001478"
     CDS             complement(4522..5022)
                     /locus_tag="VXB71_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0451573.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(5023..5616)
                     /gene="yqeK"
                     /locus_tag="VXB71_001479"
     CDS             complement(5023..5616)
                     /gene="yqeK"
                     /locus_tag="VXB71_001479"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0451574.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(5616..6245)
                     /locus_tag="VXB71_001480"
     CDS             complement(5616..6245)
                     /locus_tag="VXB71_001480"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0451575.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(6297..6608)
                     /gene="yhbY"
                     /locus_tag="VXB71_001481"
     CDS             complement(6297..6608)
                     /gene="yhbY"
                     /locus_tag="VXB71_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0451576.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(6822..7928)
                     /gene="yqeH"
                     /locus_tag="VXB71_001482"
     CDS             complement(6822..7928)
                     /gene="yqeH"
                     /locus_tag="VXB71_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0451577.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFITGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(7931..8521)
                     /locus_tag="VXB71_001483"
     CDS             complement(7931..8521)
                     /locus_tag="VXB71_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0451578.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(8473..9381)
                     /locus_tag="VXB71_001484"
     CDS             complement(8473..9381)
                     /locus_tag="VXB71_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0451579.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDKPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(9438..9998)
                     /locus_tag="VXB71_001485"
     CDS             complement(9438..9998)
                     /locus_tag="VXB71_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0451580.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            10137..11346
                     /gene="sstT"
                     /locus_tag="VXB71_001486"
                     /pseudo
     CDS             10137..11346
                     /gene="sstT"
                     /locus_tag="VXB71_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            11414..12367
                     /locus_tag="VXB71_001487"
     CDS             11414..12367
                     /locus_tag="VXB71_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0451581.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            12510..12890
                     /locus_tag="VXB71_001488"
     CDS             12510..12890
                     /locus_tag="VXB71_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0451582.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETVAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKILASLQKTVEESLEAGLDFLI"
     gene            12989..13210
                     /locus_tag="VXB71_001489"
     CDS             12989..13210
                     /locus_tag="VXB71_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0451583.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            13227..13541
                     /gene="trxA"
                     /locus_tag="VXB71_001490"
     CDS             13227..13541
                     /gene="trxA"
                     /locus_tag="VXB71_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0451584.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            13846..14379
                     /gene="queF"
                     /locus_tag="VXB71_001491"
     CDS             13846..14379
                     /gene="queF"
                     /locus_tag="VXB71_001491"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0451585.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            14429..>14639
                     /locus_tag="VXB71_001492"
     CDS             14429..>14639
                     /locus_tag="VXB71_001492"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451586.1"
                     /translation="MLKAVFEVVDKTDEVSSKHCFEVADRTDKVSLKHCFEVADRTDE
                     VSLKHCFEVADRTDEVSLKHCFEVVD"
BASE COUNT         4150 a         3239 c         2840 g         4410 t
ORIGIN      
        1 tttgaatcat catcaaaaaa catcttacat aaatcatcgt acaacgcctt actacataca
       61 tcaggatcct ctctattatc taatgaaaaa cctttgggaa aataaggata taaatcaaat
      121 agataatttt taaacttcat atttattatt ctccattaaa tctttttagg aaatttaaag
      181 tcaaattttc ctccaagcac acccgcactt actcccgcaa ctactacaag tgttgtacta
      241 attgttccta ttttcttcac gccactgttt agctcttttg ttaaataaaa caacattgat
      301 catatctgct tcacttacat acttgtaaga caactgttcg ttggtaagat cttttaagag
      361 atattctttg attgcatctg tatgaatttt gtagttaatc ttagaaattt ctctattcaa
      421 attccagcct aatgatagct tagaatttta atctgactta agtcttttgt aatcctgaat
      481 tacatacatc ttaaattcag cagaaataca taaagcaaat tcaaaggcaa tatctgtatg
      541 tgcaaatgca ccaccatatc ttccaccttt tgagataatt ccgattgctc cagttttctc
      601 tacccatttc ttaggagaca atgtaaatga attatatcca gcttccgatt taattcggtc
      661 gaattcgacc gaattgaaat tcatgttatt taagcttttc cataaaccaa gaaactcaat
      721 tgtatctttt cttctcatcc aatttttaat tacatcactc gatacttatc cgaacgataa
      781 gctccacgta aggtgttcgc aatcgaccaa actgcattga ctacatttga aatctgaaca
      841 tcgttcgact ggaatatcgg tagtttttct ttaaaattag acatttgctt cccctgtttt
      901 tatgatttac aattctcttc attataccac aaaataggcg ctttgtcaac tgtagtgggt
      961 tgaagtcagc taagctcgag aaaggacaaa tttcgtcctt tcttttttga tgttcaaagc
     1021 gataaaaatc cgttttttga agttttcaaa gtttcgaaaa ccaaaggcat tgcgcttgat
     1081 aagtttgatg agattattgg tcgcttccag tttggcatta gaatagtgta gttgaagggc
     1141 gttgataatc ttttctttat ctttgaggaa ggttttaaag acagtctgaa aaataggatg
     1201 aacctgctta agattgtcct cgataagtcc gaaaaatttc tctggttcct tattctggaa
     1261 gtgaaaaagc aagagctgat agagctgata gtgatgtttc aagtcttgtg aatagctcaa
     1321 aagtttgtct aaaatctctt tattggttaa atgcatacga aaagtaggac gataaaatcg
     1381 cttatcactc agtttacggc tatcctgttg tatgagcttc cagtagcgct tgatagcctt
     1441 gtattcatgg aactttcgat ccaattgatt catgatttga acacgcacac gactcatagc
     1501 acggctaaga tgttgcacaa tgtgaaagcg atcaagaacg attttagcat tcgggagtga
     1561 aacagtctgg gagactgttt cagcctgagc ctagaaattt gaaagcgaag ctgtttagcc
     1621 aagtcatagt aagggctaaa catatccata gtaataattt tgacgcgaca tcggacagct
     1681 ctatcgtagc gaagaaagtg atttcgaatg atagcttgtt ttcttccctc aagaacagtg
     1741 atgatattga gattgttaaa atcttgcgca atgaagctca tctttccctt tgtaaaagca
     1801 tactcatccc aagacataat ctcaggaaga cgcgaaaaat catgtttaaa gtgaaaatca
     1861 aagagcaaac taggaaacta gccgcaggct gtacttgagt acggcaaggc gacgttgacg
     1921 cgatttgaat ttgattttcg aagagtatta ttcgtaaaaa atctcaaaaa gtccaccttt
     1981 cggtagactt agtttgtttc tattctaatc ggcactcttc caaaattctg ttgtgctata
     2041 cttagatttc ctagttggta aatctggtct gctttttggg tcatagcatc ccaaggttct
     2101 ttgccaattc ggctgactag actgacctga cctttcaaag acttgagatg ttgcctgcct
     2161 ttttcagtaa atccaaggac atgaatggct tctggcaaga cattttctct agcctgcgcc
     2221 aagatatagg acaagaggcg tctgacacgc gccttggtgt aacgtttggt agtcactaac
     2281 tcgaccaatt cttccacaga ctgggctgtt ttaatagctt ctttaatgcg cacagccatt
     2341 tcttgattga cctgatagat ggtggttagg tcgggatttg acaagatttg atagcggagc
     2401 aagggaaaat agtcttccca gatcacctta ctggcctgct caaatagggc aacagaaggc
     2461 ataaaacgtt ctaagaaatc ttggtccttc tgatgttgac ggagggctgt cgccgaggca
     2521 aagtccacat ctttattcac agaatggtaa cctgccccct gacgctgaat cggatgcagc
     2581 ttgatattcc gtcctgcaac cgccttggca taggccagag caagaacatg attgggggta
     2641 ttacctgaaa aatcaagacc agcaaattcc ttccacatag cttgggtttt ctggggatag
     2701 gaaagggaat caggcagatt ttccacaaat ttctccatct cagtaccttt ctctgtgtat
     2761 aagtcagcga ttttctgata atctcgaact tcctctgtcc caaaaactag actatcaatg
     2821 cccaagcgat ccaagatatc cacagctcct tgaccaaaga aatcagctgc ctgaacactg
     2881 actaaaaagg gcaattccac taccaagtct gcgccatttt ccagcgccat ctgggccctt
     2941 gtccacttat ccacaatagc aggctctcca cgctgcatga aattccctga catggcaaca
     3001 attttcagtc cctctgcctg atccagcagg tatttatggc cattatgaaa aggattgaac
     3061 tctgcgataa tacctgtgat ggtcatgatg ttctcctact tctgcgccac aaaaaaccaa
     3121 cgggtgctag tttctgttgg ctccttatcc tcaaagtctg catagagttt gaaggactta
     3181 aatccagcct gttccagcaa gatatcatag gtcaagatct cataggtcct ctcctcatgt
     3241 acttcatcgt ggcgactaaa ggaaccgtca gcctccttga taaagaaagt cagctcatgc
     3301 acgatggagt gaggagcttc gtcctcatat gtatcccaaa gcatggcaaa atcttccgca
     3361 ttttcatggt aggaatagcc agggaatact tcatctgtct ggtaggtcga gtgcacgtca
     3421 aagatgaaaa ctccctcttc attcagcgca ttgtacacgt ccttaaagac gtcccctact
     3481 tccacctcat cctgcatata gcagatagag tccgaataac acgtgacaaa atcgtatttc
     3541 cctgccttgg acaaattcag catattacct tctataaaag caatcttttg cttggctgaa
     3601 gttgctctct tctccgcaat cttcaacata tccgcactca agtcaagtcc agtcacatca
     3661 aaaccagcct gagagaagcg cactgattga attcctgtcc cacaagccaa ttccaagagt
     3721 ttctttctct ccttggtctt aggcaaatga cgcagagaaa aattcgtcca tttgtcgtat
     3781 aaactatcgt ccatgaccgc atcatagacc gccgcaaagg tttcataagt cgccataaaa
     3841 catgatacca agtccgcccg taattcgata gaaaattagg agccttacga tggagccgag
     3901 ctccaaggaa ggctatctat tttccgagaa ttacaggacg ggttcaaatc ctttctaaga
     3961 tacaaagagc cttaaaagca aagagtacat aggaaacttt cttccctatc gtcagataca
     4021 aagaaagtta ctttttatct cagcttttag ctcgtgttca gtttcgaaat gaaacaaaca
     4081 cgaggccctt tacctttcta tcaatttttc taaaataagc aaagaaaccc agttgactac
     4141 aactgagttc atcttctaag caagagcttc tgaaatatct actgaattcg cctcatgcca
     4201 tagcttctct agattataat gggcacgcat ttcttctgaa aagatatgca cgacaacagc
     4261 accgaggtcc agtaagaccc agcctccagc tgcatcgcct tcgacatggc tacctttaaa
     4321 gcctgcttga gctacttttt cacggatatt agctgcgata gcgtccaact gacggctatt
     4381 cattgagcta gtgatgacaa agtagtccgt cacactagtc aaatcttgta catcaagtgc
     4441 gaggatatcc tccgcacgtt tctcatcagc cgctttcacg actagttcta gtaattcttt
     4501 ttcgttcatt taatcctctt tttagaaaat atgtttgtaa tctagaacat ctgcaaagcg
     4561 ctcctcccaa atgtcctcat aaaattcatt aatcgtttct gctggaatgt catccccatc
     4621 aaaggttgtg acagcacctt ctggaacaat aagctgatag ccatattcaa aggcaacctt
     4681 gacagaggta tccacacaat attctgtctg cataccacat aaaactaatt tttcaatccc
     4741 ctgcttatcc aagtattctt ttaagccagt ttctttgaaa atactgttat acttcttctg
     4801 aaagaccttt tcagcaggtt ttcgatttaa aagcgcagat aactgccaat cttctgatgt
     4861 ttgagcttca gagttctcaa tatgttgaac atagataatt tcaatattct tgcttctagc
     4921 ctggttttgt aaataagaaa ttttttccaa tagacttttt gtctggaacc cagtttctac
     4981 taaaacattc tgaacatcaa tgattataaa agccgtcttc atttagtcct ctttcaaata
     5041 gtgcacaaag gcgttatagg tttcaagggt ttggggatag atggggaatc cctgatgagc
     5101 tagatactcc acggtacgag ctgtttcgta ggccaccgcc ttattgagcg atagacttgc
     5161 aatctcacgc gccacatcca ctccaggaaa tgcccgattg tgctcgatat agtctgcgac
     5221 gtagatgacc ttatctaggt ctgtcatttg accagctccg actgtatgaa tttcaatggc
     5281 tcgcagaatt tcagaatcat gcaaatccaa atcttcctga attttgtaaa ttccgaccat
     5341 accatgccag acattgttgc cccagttttt gaggtcaggg tctagctggt aacggtcaat
     5401 caaggctaga aattcctgat ctgacaactt tttagcatag tcatgaagaa gacctgctag
     5461 acttgctttc tcaacatcta caccaaagcg ctgagctaat tccatagcgg cacgctccac
     5521 acctagacaa tgggttagac gtttctcagg tagaagctct gccatttttt ccaacaaggc
     5581 ctcacgggag cagttgatat agtcttgata ggacatcagt agagcccctc cttctcgatg
     5641 tagtctagca ctggctgagg taggagaaag ttgggtttcc gaccttgggc aaggaagtcc
     5701 cgcaccatgc tggacgagat atccatgagc ggtacgtcca cccagataac tggataggaa
     5761 gtccctacct tgtagcgtgg acgctgaacc cccacaaact gaaccatgtc aaccagttca
     5821 tcaattcggt accacttagg cagatagtca accatgtcgg caccgatgat aaagtaataa
     5881 tccgtatctg gattcttctc tgtcaaaatc ttcatggtgt cgtaggtgta ggaaataccc
     5941 ttgcgctcca actcaatggt ttcaatgact aggccgtcaa ttccctcaat tgccaactca
     6001 agcatcttga gacgatggtg ttcagggatg gtttcctttt tatcaacgtg aggaggttgg
     6061 tattcaggca tgagcagaac ttgatccagt cccaactgtt gccgtacttg atccgcaaca
     6121 ataagatggg cattgtgaac agggttaaaa ttccccccta aaatcccaac ttgtttgcgt
     6181 tttttctcct tgatttctgg ctccaactct accttggtaa agggagtcaa tagttcgatt
     6241 gtcataggct agtccccttt atttctctat gaaaacagtt atttggagtt tcggtcttag
     6301 atttctttga ctttcttaga aatcttgcga ttttctttct tgctagattg tttaaacaaa
     6361 atcaagatgc gtcctatttt ttggactgta tccacaccga tttcttcttc caaaatttca
     6421 gctacttcgt ggatgttttc atctgtgttt tgtaagagag taaccttgat taattcacgc
     6481 gcatcaagag cttgacggac gctggttttg atttggtcgt tgagtccatt tttcccgatt
     6541 tggatgatag gtttgagggt gtgtgcctgg ctgttgagga aggcacgttg ttttgatgtt
     6601 aatgacataa ttttcttcct tgttttttga tagttatttt aggtggtgag ggacggtcgg
     6661 aactaatttt ccaaagattt catctttgaa aaatggattt cctgacctca caattgagcc
     6721 ttggtctcaa ttgtgcccct tgccaatcta cagattggca atcacaccac ggcaataact
     6781 atcgctatat gagctcactt tgttcgctca gcgattttgt tttaaataat tgcttttcgt
     6841 gtgacgacgg cgacgccttc tggtgcccag acggcgactt ttgctgtgcc tgttacacga
     6901 atccagccta ggcctgagat gactaggtct gtcttatctt taatggtaaa gacatgctgg
     6961 actagccttg ggaaatcttc tttttccttg ctatttggtg gtgtcagaag agttcccagg
     7021 tgcttatcgt agaaagcact agctccttca agcttgctac gatggagttt gagttcattg
     7081 tcaaagaaag cagtaaatcc ttgcttttct cctgttataa agtcaaagcg tcccaaacca
     7141 cctaaaaata gggtttgctc aggattaagc tgataggtct taggcttgat ttccttttta
     7201 ggactgacat acttgaggtt tttggccgtc aaatagtgag ccatctggtg gcggtggata
     7261 attcccggcg tatcgtaaat ataagatccg tcgtcaagcg gaatctctat tttgtccaag
     7321 gttgtccctg ggaagcgtga agtagtgatg acattctgat cacccgtgat ttcttggata
     7381 atagcattga ttagagttga ttttccaacg ttggtcacac cgaccacata gacatcgcgg
     7441 cccttacggt agtgttcaat cttgtcaatg acttccttaa tggcatgttt attttgtgct
     7501 gaagttagga ccacatcgac tggacgaaga ccttcttcat gggcacgttt catgagccac
     7561 tggctaatct taccagactt aactgactta ggaaggatat cttttttatt tcctaccaag
     7621 aggacatcat tgcccgagac gaaacgtggt aaacctggga tgacagatcc attaaaatca
     7681 aagatatcaa tgacattgac cactaaagca tcactgtctc ccacctcgtg caagagcttg
     7741 aggaaatcat cgttcgtcaa ctggacatct gtgatttcat tgtagtggcg gagacggaaa
     7801 cagcgttggc aatagacttc gccagtctcc aaaccttttt caagtgccga ctggggggta
     7861 aaaccaagac cagctttatc tgtcgtctga atggttgctc cacaaccaat acagagaatt
     7921 tcttccatag ttaaattcct tttttatatg taatcggtcc gtacttttca gtgatttttc
     7981 tcataacacg acgctcacga gttcggttaa tctgcgtttt gattgagtca tgttggacca
     8041 agggtttgac taaaattgac cgaatccctg cacggtgggc tgctcgtata tctgtcatga
     8101 gctggtcacc aaccatgacc acttcctttt tgtcatagtg gaattccttc atggcacggt
     8161 caataccaaa tgtgaagggc ttcaaggccc agtaaacgta atcaatccca aatttctcaa
     8221 ctgctcgttg aacgcgtttt ttggtgttat ttgacactac gataatgcca atacccgcgt
     8281 cccgaaggtc atgtagccat tgcttcatct ctggcgttcc atcagggttg ttccaagcaa
     8341 tgagggtatt atccaaatcg accaaaacag ccttgattcc ctgcgcctgc aggcttggga
     8401 ctgtcagatc atagactgct tccacagcaa aatctggtat ataattttca atcgccattc
     8461 tggctccttt tcttaacttt ttttcgcaat tttccttagt aacaaggata aaacaatcca
     8521 caaacctgca ctagccaaac tgatatagag ccaagcatgg ggcttatctg ttaaaggtaa
     8581 gggaacattc attccgaaaa agcctgtcac gactgccaaa acagctagca agactgaaat
     8641 gatagtcaag gttgtcaaat tgtcattcag attattgttt agaatattgt tgtaagaggc
     8701 tgaaagctgc tgtaaaatct gagagattag gtctgtcatg gataccagct gatgagcctc
     8761 aatcatggca tcatcaaact gttctctctc aatctcatca aaactacgat acaaggcatg
     8821 accttgaata tgctctaaca aaatccgatt ttgtttggca gctgccgtca gataaaccat
     8881 accagtctcc aaatcagaca gggcaaagag gtttttcttg gtagttcgct ggcgcaagag
     8941 gtcattgacc tcatccctac tcttgtccat ctgctcaatg acaggatagt aggcattgct
     9001 gatgatttcc agactggcaa agagaaactt ataaatcgaa agcgtgtcat ggttctccag
     9061 ataacgagtc atctgttcaa tgacataggc gttcttggta ttactaatgg taatcaggcg
     9121 acgatgctcg acaataaagg tcatgggaaa agtctcatag taggccttgt ccttttttac
     9181 gtctaggaca ttatagataa aggtaaccgt cccactttca cggtggtagt ccatgtgggc
     9241 gcgctcgttt ctatccagtg cgtattcaat ggtttccttg tccaaaccgt aaatttcaga
     9301 aaggtcttct agtttattca actttcctag gtctaggtct atccaggtac aaccattgcc
     9361 caactgcttt tctaaaacca tcttttctcc ttattaaact ccctctattg taccacaaat
     9421 tacttaaaat aacaggtcta gtctgtgcgt gagaaattgc taacaactgt gatatttcgg
     9481 ttagggacaa agtgaagggc ttgctcctcg ctacgaagct gtgtcgtacg aattcccaca
     9541 ctgacaacct tacccgatac agtaatcggt ccatttgtca gaacgacctc atctcccaca
     9601 tccagttgac gttcaaagag gatgaaaaag ccattgatga catcagacag aaagccttgg
     9661 gctcccatac caatcgctac cccagcaata ccagctccag ccagcaaact agaaactggc
     9721 aaacctaaaa tcgacaaaat gcagtagagt aaaaagaaat atagcgtata attaaacaca
     9781 ttttctagta aacgtgagat ggttttttgg cgtccgacat catgacgaga catttttaga
     9841 gaaggtttga caattctctg caccatggta tgaagcattt ttttagcaat ataaaataca
     9901 atcaaaagca gtaaaagaga aatgaccttg gttagaatat tctcgataat ggttgtcaca
     9961 tctagctttt caatataagc ctgaataaat ttttgcatat aaaactcctt tatttcatta
    10021 taccatattt tcatcagtct cattctccat aaatattcaa aaaatagaca gaaaattctt
    10081 gattttgtct atcatttata ctataatcat aatcactaca caaaaaggag attattatga
    10141 aaagaatcat tcatgcttgg aataaggcaa gccttgtcaa gcgtatcttg attggtatgc
    10201 tttgtgggga atcctaggac tgacccttcc taatctctca gggattgggc tactcgggga
    10261 tttattcgtt ggaggtctga aagctgttgc tcctatccta gtctttgccc tcgttgccaa
    10321 tgccctttcc caacatcaaa agggacaaga tagcaatatg aaaactgttg ttttcttgta
    10381 tatcctatga tagggacttt cgccgctgct cttgtagctg tactagcaag tttcatcgtc
    10441 cctattgaaa ttaccctaaa tagtgccaat actgaaattg caccaccaga tgggattggg
    10501 caggtcctca gcaacctctt gctcaaactg gttgacagcc cagtcaacgc cctgcttact
    10561 gctaactata ttggaatctt atcttgggca gtcatttttg gaatcgctat gagagaagct
    10621 agtaaaaata gtaaagaatt gctaaaaact atcgctgacg tgacttctaa aattgtcgaa
    10681 tggatcatca atctggctcc atttggaatc cttggtcttg tttttaaagc catttctgac
    10741 aagggagtcg gaagccttgc caactacggt attttattgg ttccattagt aacgactatg
    10801 ctttttgttg cccctgtggt caaccctttg attgccttct tctttatgag acgcaatcct
    10861 tactctctag tttggaactg cctccgtgtc agcggtgtga cagccttttt cactcgtagt
    10921 tctgcgacta acattcctgt caacatgaaa ctctgccatg accttggact caacccagat
    10981 acctattctg tttctatccc actcggttct actatcaata tggctggagt agcgattacc
    11041 attaaccttt tgacccttgc tgcagttaac actcttggaa ttcctgttga ctttgccaca
    11101 gcctttgtcc tcagtgtggt agcagctatc tcatcctgtg atgcttcagg tattgccgga
    11161 ggttccctcc ttcttatccc agttgcttgt agccttttcg gtatttctaa cgatattgcc
    11221 atacaaattg ttggggttgg ttttgtgatt ggtgtcatcc aagactcatg tgaaacagcc
    11281 cttaactctt ctacagatgt cctctttacc gccgttgccg aatacgcagc aacccgtaaa
    11341 aaataactca tcaaggcaag cctgctcatg tcttgtcttt tacgctttta ttctaactta
    11401 ttaggaaatt cttatgtcta ttagccaacg tacgaccaag ctcatcttag ctacctgtct
    11461 tgcctgcctg cttgcttatt ttctcaatct ttcgtcagca gtttcggctg gaattatcgc
    11521 tctcttgagc ctatctgata cgcgtagaag tactttaaaa ctggctcgca atcgtctttt
    11581 ttctatgctt ctagctctgg ctatcggtgt tctagctttt cacttgagcg gatttcatat
    11641 ctggagtctc ggcctctatc tggccttcta cgttccttta gcctacaaga tgggctggga
    11701 aattggcatc acaccaagca ctgttttggt tagccatctc ttggttcaag agtcaacctc
    11761 tccagacctt ctagtcaatg aattccttct ctttgctatt ggtacaggat ttgccttgct
    11821 tgttaatctc tatatgcctt cacgagaaga ggaaatccag cactaccaca cgctggtgga
    11881 agaaaagtta aaagatatcc tccagcgctt caaatactat ttatccagag gagacggacg
    11941 caaccgagca cagctggtag cagaattaga cacgcttttg aaagaagccc tcagactggt
    12001 ctatttggat cactctgacc acctctttca ccagaccgac taccatatcc actactttga
    12061 gatgagacag cgacaaagtc gtatcctgag aaacatggcc caacagatta acacttgtca
    12121 ccttgccgcc agtgaaagcc tgatcttagc gcaactcttt tcaaaaattg caggtcaact
    12181 gagccagacc aatcctgctt ctgatttgct agatgaaatt gaacgttatc tggaagtctt
    12241 ccggaaccgc agtctgccca agacaagaga agaatttgaa acccgcgcca cccttcttca
    12301 actcctacgt gaagccaaaa ccttcatcca agtaaaagtt gatttttacc aaaaatatag
    12361 acagtaaaaa ataaaaccac taaaaaacag agcttgccag cattcttgaa aagtagtata
    12421 attattgcat gcgcaatcat cttgtgacgc agagactgcc cgttaatgga ctttcttcta
    12481 tttatgactc taaaaagaaa ggagacacta tgacctattt ggaaaaatgg tttgacttca
    12541 atcggcgtca gaaagaaatt gaaagtctct tggaagagac cgttgcccaa cagagcgagc
    12601 aaagtctgac cttgaaagag ttctacctgc tctactatct ggacttggct gaagaaaaat
    12661 ctctacgcca gattgacctg ccagataagc ttcatctgag cccgagcgca gtttctagga
    12721 tggtggctcg cttggaagct aaaaattgcg gtctactcag tcgcatgtgt tgccatcaag
    12781 atagacgctc tagttttatc tgcctgacaa atgatgggca aaagatactg gcctcgctac
    12841 aaaagactgt cgaagaaagc ttggaagcag gtttggattt cttgatttaa gatgatttta
    12901 gaaaaagttg cgtgcgcaat catttttctt gacattctct tttataagga gtaaaataaa
    12961 gttagcatta aacaaaggag ttttaaatat gattgaaatt acctatatag atgccagcaa
    13021 gaacgaaaga actgtgactt tcgagtctta tgaagacttt gaacgttcgc aacaagcttg
    13081 ccttatcggc gtcgcagact actaccctgt ccaaaaatta acttacaagg gtcataattt
    13141 ggactaccat gggacttatg gagatatctt cttctatctc atgaaacaag atttaagcca
    13201 atataactaa aaaaaggaga aatacaatgg caaaagcaat tacagatgca acattcgaac
    13261 aagaaacaaa agacggtttg gtcttagtag acttctgggc aacttggtgt ggtccatgtc
    13321 gtatgcaagg tccaatcttg gacaaattgt ctgaagaact ttcagaagat gtcttgaaaa
    13381 tcgttaaaat ggacgttgat gaaaatccaa acacagctcg tgcttttgga atcatgtcta
    13441 ttccaactct tctcttcaaa aaagacggcc aagttgtcaa acaagttgca ggtgttcaca
    13501 cagcagaaca aatcaaggcc atcattgctg aattgagcta atcaaacgag agaccaagta
    13561 ctttctttgg tctctttttt cttgcccttt gccatttttc aaaaaatatg ctagactata
    13621 gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa atcgatttaa
    13681 ctgtcctgat cgatttgtcc tgttcttatt tcattttact atataagtag aatattacga
    13741 tgtttgggat atgccatcgc taaaaaaact cgatttggta ttttttagct ccctaatagg
    13801 agctttttgc atgctctgaa catttcccat tttggaagga gtactatgaa acgtcaatca
    13861 gccttggtcg tctttagtgg tggtcaagat tcaacaacct gccttttctg ggttatgcaa
    13921 cactatgaaa cagtcgaagc tgtcaccttt gcctacggcc aacgtcatca cctcgaaatt
    13981 caaattgcta gagaaatcgc taaggaacag ggcattcgtc accatatcct cgatatgtct
    14041 ctgctgggac aaatcactgc tcagccagac tttgcgacga ttcatatttc ctacattcct
    14101 gacaagctct gtgtcgagtc aaaatccctc aaactatatc tatttagcta ccgaaatcac
    14161 ggagatttcc acgaaaactg tatcaacacc atcgggaaag acttggtcaa cttgctagac
    14221 cctcgctatt tagaagtctg gggaaaattc actccgcgcg gtggcatttc aatcgacccc
    14281 tactacaact acggtaagca aggaactaag tatgaggact tggcagaaca acgcctcttc
    14341 caacacgacc tttatccaga gaaaattgac aaccgctaaa gtcatactca atgaaaatca
    14401 aagagcaaac taggaagtta gccgcaggtt gctcaaagca gtgtttgagg ttgtagataa
    14461 aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg acaaagtcag
    14521 cttaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagcttaa aacactgttt
    14581 tgaggttgca gatagaactg acgaagtcag cttaaaacac tgttttgaag ttgtagatg
//
LOCUS       DAVLAQ010000044        14250 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000044 DAVLAQ010000000
VERSION     DAVLAQ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.044"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(778..1647)
                     /locus_tag="VXB71_001493"
     CDS             complement(778..1647)
                     /locus_tag="VXB71_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0451587.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1871..2392)
                     /locus_tag="VXB71_001494"
     CDS             complement(1871..2392)
                     /locus_tag="VXB71_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0451588.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(2350..3456)
                     /locus_tag="VXB71_001495"
     CDS             complement(2350..3456)
                     /locus_tag="VXB71_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0451589.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVVVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGCLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3567..3821)
                     /locus_tag="VXB71_001496"
     CDS             complement(3567..3821)
                     /locus_tag="VXB71_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451590.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(4161..4694)
                     /locus_tag="VXB71_001497"
     CDS             complement(4161..4694)
                     /locus_tag="VXB71_001497"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0451591.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYKKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(4681..4896)
                     /locus_tag="VXB71_001498"
     CDS             complement(4681..4896)
                     /locus_tag="VXB71_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0451592.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(4863..5006)
                     /locus_tag="VXB71_001499"
     CDS             complement(4863..5006)
                     /locus_tag="VXB71_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV0451593.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            5240..6958
                     /locus_tag="VXB71_001500"
     CDS             5240..6958
                     /locus_tag="VXB71_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0451594.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            7069..7416
                     /locus_tag="VXB71_001501"
     CDS             7069..7416
                     /locus_tag="VXB71_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0451595.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7695..8531)
                     /locus_tag="VXB71_001502"
     CDS             complement(7695..8531)
                     /locus_tag="VXB71_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0451596.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8544..9173)
                     /locus_tag="VXB71_001503"
     CDS             complement(8544..9173)
                     /locus_tag="VXB71_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0451597.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9183..9824)
                     /locus_tag="VXB71_001504"
     CDS             complement(9183..9824)
                     /locus_tag="VXB71_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0451598.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(9970..11199)
                     /locus_tag="VXB71_001505"
     CDS             complement(9970..11199)
                     /locus_tag="VXB71_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0451599.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11189..12355)
                     /locus_tag="VXB71_001506"
     CDS             complement(11189..12355)
                     /locus_tag="VXB71_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0451600.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVIFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12499..13512
                     /locus_tag="VXB71_001507"
     CDS             12499..13512
                     /locus_tag="VXB71_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0451601.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
     gene            13652..>14250
                     /locus_tag="VXB71_001508"
     CDS             13652..>14250
                     /locus_tag="VXB71_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0451602.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLHYDRA"
BASE COUNT         4370 a         3052 c         2496 g         4332 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatac ccccctaatc
      361 gcttatttta tagcaaaatg aaatagaaac tgaacatttt gttgaggaag gtaaatcaat
      421 tcctcacaat gtttgagaaa gaagggagga ctattccaac ttcaacccac tataaagcag
      481 acttacaaga tagggaaccc atctccgata atatatagta gaatgaaaac tgcacaattt
      541 gattggagaa ttcaaaccaa tttctcacaa tgttttagaa acaagggtct attatttcaa
      601 ctgcaaccta ctatagtcca ttgaagctgg aatagcccac tgagacttct aaaccactgc
      661 tggagaggag tttgtttaga gtttctttca tttccctaaa aaatcaaaaa gagagaacca
      721 gtctgatcct ctcttattta tagatggtgc tcactcaaat gttaaaggag ctatttctta
      781 gagataaagg aatttgaata cagctactgc cgcaattgct gctacgatag gtgctactac
      841 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
      901 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
      961 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
     1021 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
     1081 aactgtttgt cctgcttcta ttgccttttg tttcatgaat tgaagcactt cagcaccaaa
     1141 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt
     1201 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
     1261 aatagttgag aaagttccca agatgttatt tgggttttca gttttcaagt agaatggacg
     1321 gtatgttgcc acaactaagg cttggccaaa gatagctccc aagacttgcg cgataatata
     1381 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agccctagag tgaaagcagg
     1441 gttgatgtga ttcccagata cgttaccaaa catcaaggct gggatcataa cccccatacc
     1501 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
     1561 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
     1621 atacttcagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
     1681 ccttatttta tcaattttta ccctatttag caactgattt ctggaaatat ttttaaaaaa
     1741 ataggattca tagtttccca gttcaacgga cttgtaagcg tttttattct tcacgaaaga
     1801 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
     1861 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatcct agactagcta
     1921 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
     1981 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
     2041 cagtttttgg agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc
     2101 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     2161 tatctggatc tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg
     2221 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     2281 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     2341 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     2401 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     2461 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     2521 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     2581 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     2641 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     2701 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     2761 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     2821 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     2881 atcatttttc aatgatagca aacacccttg ttcatcaaca tagcgaactt tcacattttc
     2941 tgagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     3001 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     3061 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     3121 acggtgactt tgagtgttta ctactactct ttcattattc tctgaaaata cttgtacggt
     3181 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     3241 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     3301 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     3361 ctcttcagaa ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt
     3421 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     3481 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     3541 ttgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     3601 gtcttcagta gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc
     3661 caagttgggg tattaggagt atctttatca gcctgtttca agacattatt caagtcattt
     3721 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     3781 gacttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     3841 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     3901 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     3961 tacgattttt aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     4021 tcaaaccttt cttatacaag tcttcattct aaacgatttc ggctacacgg tgaatggttt
     4081 gattgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg
     4141 ttcctttaga accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata
     4201 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     4261 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     4321 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     4381 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     4441 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     4501 gaagttcgct caaaacgacg tccgctaatc tttttataga ctttctcccc tctaggagcc
     4561 cgtgcataag gacgatagag gtagcggtcg attcctgttt catcaatata tacgattggt
     4621 aaatctttta ggttatccaa aatatcaaga aactcagcga ctttctctgg ctcttgttcc
     4681 ttaaagctcg tcatcttttt ttaaagtgac cttaatatac tttaaagctg cccatacgga
     4741 gggcagagca caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc
     4801 tacaaaggct ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct
     4861 ctctatgtgt ccttgttcac atctttcttt tcccacgtga agagagttct gacgccaaca
     4921 ccaaaaaact tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc
     4981 tgtttaaaat cagtactata tgccatagct ttattataat atgcttgttt aaaactaagc
     5041 aactatatca atgttttgtt attagaagac ttactttttt tactgaaatc gaatttttcc
     5101 taacctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     5161 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     5221 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     5281 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     5341 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     5401 tacaaaccgt atcaacatct acgttgttcg acaagctact gaaggattgg ctcgtttgat
     5461 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     5521 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     5581 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     5641 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     5701 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     5761 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     5821 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     5881 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     5941 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     6001 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     6061 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     6121 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     6181 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     6241 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     6301 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     6361 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     6421 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     6481 acgtgataaa gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg
     6541 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     6601 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     6661 gattatggct aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt
     6721 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     6781 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     6841 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     6901 agaatcacaa gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag
     6961 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     7021 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     7081 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     7141 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     7201 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     7261 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgttatgg aatcccaact
     7321 gtaccaggtt ttattcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     7381 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     7441 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     7501 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     7561 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc
     7621 tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgtagtctca
     7681 gccactattt tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac
     7741 catttttggc tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt
     7801 atcttcttaa ccaaggttgt atcttcctta cgggctccaa ccgcaaaagc ttctgtttct
     7861 agtccaactg taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt
     7921 gcatagacac ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct
     7981 tcattaaagg tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct
     8041 ggatttgctt caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca
     8101 gtcatatcct ttgcagtcgt gataccagat gattttttcg taaccaatac ctgctcattc
     8161 ttcatatatg agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca
     8221 ttccaaatca gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc
     8281 ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca
     8341 aatcctgcat aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat
     8401 ccaatagtaa tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta
     8461 gaatttttcc cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc
     8521 cattttttca tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata
     8581 ttttcagcaa actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt
     8641 tgcaagatta gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca
     8701 tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt
     8761 tgcccaccag atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc
     8821 aagagtccac tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc
     8881 gataaagtca aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca
     8941 aatcctagta ggttgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag
     9001 atttgccctg aatcaatggt ttcaagaccc gcaagcatac gtaaaagagt cgtcttacct
     9061 ccaccagaag gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta
     9121 gacaggattt gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc
     9181 tcctatctat aataactata cttcttctca acttttttgg aaataattgt cacaatccca
     9241 atcaaaatca aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta
     9301 gcagctgttc gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta
     9361 tccttgacca aactcataac ttcattaaag acactaggaa gaacgatctt ggtcacttgg
     9421 ggcaagataa tatagcgcac tctgtcaaaa gggctaaact tcaagacctt ggcggcctca
     9481 tactgtcctc ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca
     9541 tagttgagaa caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt
     9601 gggagcacat aatagataaa aattagttgc aagagtaagg gggttcctcg cataacccag
     9661 atgtaaatgt taatcagata atggaggggc ttccaatgga cttgcaaggc aaaagcaatc
     9721 aaaacgccca agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc
     9781 gcaccattca gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa
     9841 gtaattgttc ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt
     9901 ctaccatata caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt
     9961 taaacattct tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt
    10021 taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata
    10081 gatatagtgt tccagaaatt ctggattgtc cttcaaatct cctgtcaact cttgataatg
    10141 ctcataagca gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt
    10201 caaaagattt tctggctcct cactctgcaa gtctagaata tcctcataac gctcctgctc
    10261 cagataaata gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc
    10321 agcaagaaga taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc
    10381 agctagcaag aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag
    10441 ggcttcttga acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc
    10501 aaagtcagga gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc
    10561 ttgatcaaaa taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag
    10621 ggctttttct aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaagcc
    10681 aattcgttga taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc
    10741 ataggcttga atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa
    10801 catcaagaga gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc
    10861 tgtcaaacct tccagctggt aaaggtctgc cttcaaaacc aaagacgaga cataccagtc
    10921 actgtcagct tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct
    10981 agcaattgca gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat
    11041 ttccttggcc tgaggataga aaccaatccc ttcaagataa gttgccaact catacagaag
    11101 atcacttgaa tcattttcta aagctttggc gaaataatac tcagccttag ttaaatcttg
    11161 ctcctccaaa gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta
    11221 attcatatag accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag
    11281 cagaggcata aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag
    11341 ttaacaaaac aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg
    11401 gagagacaaa acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa
    11461 gcatgactgg accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac
    11521 caagataagg gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta
    11581 gaccaataat cttgaagaag atgataaata ttactgctac aataatagcc actgtcactt
    11641 gccctcgaac atagttggac aactgttgat tcacatctga taaaacttgt ccaacaggtt
    11701 ccttcaattt tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca
    11761 agagataaaa gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagctccac
    11821 taataaaggc actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag
    11881 cctggctaga aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcaggt
    11941 gctgggctac caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc
    12001 ttgcaaaggt caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga
    12061 taaagagagc gatgataaca aagacaatag tgatagctat aacacgatta accttatgct
    12121 tctccatcca atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg
    12181 gcaacatcac aactgctaaa aaatctaaaa caggtgaaaa tagaaaacta atcttactta
    12241 aaataaaaag attcaatccc aataataagg ttactaaaaa taccgtaatt gccttgttat
    12301 ctaaaaacca cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata
    12361 cttcctttct attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag
    12421 tgcttacatc taattgaatg tctttaattt gcttgttttt gtgatataat agtcttatct
    12481 ttacacagag gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact
    12541 tctcaaggga tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa
    12601 ctttttgcag ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac
    12661 actgttggta gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg
    12721 ttaaatcatg ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt
    12781 gatttggttt acgcagccaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa
    12841 gatggtagtc ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat
    12901 caagcttccc cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc
    12961 gacttgggaa ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag
    13021 ctctatacct atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac
    13081 tataaaatcg cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat
    13141 ggcgttggcg aatttgtacg tatgcaggtt atttcaactt taccagaagc ttacgaaggc
    13201 tttaatggaa ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac
    13261 cgtggccatg attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta
    13321 gaaatcgttc caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa
    13381 tttctcattg ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac
    13441 aatggtcgtc tagcagaact ctccaacgaa ttccatgttc ccgaagcagt ctgcatccgt
    13501 tttgctcctt aaaacaccat aaaaaatggc tctataatat ttgtagtggg taaatcccct
    13561 atggatatta tggagcctat ttttgtgtag aaaaaaagtc ccataagatc tataatgaaa
    13621 agcgatcaaa caactcatta gaaagattca tatggaacaa ttacatttta tcacaaaact
    13681 actcgatatc aaagacacaa atatccaaat tatagatgtc gtcaataggg attcacacaa
    13741 agaaatcatc gccaaactgg actacgacgc accatcttgc cctgagtgcg gaaaccaatt
    13801 gaagaaatat gactttcaaa aaccttctaa aattccttat cttgaaacga ctggtatgcc
    13861 tactagaatt ctccttagaa aacgccgttt caagtgctat cactgttcaa aaatgatggt
    13921 cgctgaaact tctatcgtca agaagaatca ccaaatccct cgtatcatca accaaaaaat
    13981 tgcgcaaaag ttgattgaga agatttctat gaccgatatt gctcatcagc tggccatttc
    14041 aacttcaact gttattcgta agctcaatga ttttcacttt aaacatgatt tttcttgtct
    14101 tcctgagatt atgtcttggg atgagtatgc ttttacaaag ggaaagatga gcttcattgc
    14161 gcaagatttt aacaatctca atatcatcac tgttcttgag ggtagaacac aagctatcat
    14221 tcgaaatcac tttcttcact acgatagagc
//
LOCUS       DAVLAQ010000045        14224 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000045 DAVLAQ010000000
VERSION     DAVLAQ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14224
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.045"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            82..879
                     /locus_tag="VXB71_001509"
     CDS             82..879
                     /locus_tag="VXB71_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0451603.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1027..1149
                     /locus_tag="VXB71_001510"
     CDS             1027..1149
                     /locus_tag="VXB71_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0451604.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1171..2211
                     /locus_tag="VXB71_001511"
     CDS             1171..2211
                     /locus_tag="VXB71_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0451605.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDHLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2382..3656
                     /locus_tag="VXB71_001512"
     CDS             2382..3656
                     /locus_tag="VXB71_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0451606.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELCLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3666..4544
                     /gene="truB"
                     /locus_tag="VXB71_001513"
     CDS             3666..4544
                     /gene="truB"
                     /locus_tag="VXB71_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0451607.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4785..5087
                     /locus_tag="VXB71_001514"
     CDS             4785..5087
                     /locus_tag="VXB71_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0451608.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5195..5833
                     /gene="udk"
                     /locus_tag="VXB71_001515"
     CDS             5195..5833
                     /gene="udk"
                     /locus_tag="VXB71_001515"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0451609.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5961..7301
                     /locus_tag="VXB71_001516"
     CDS             5961..7301
                     /locus_tag="VXB71_001516"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0451610.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7279..7491
                     /locus_tag="VXB71_001517"
     CDS             7279..7491
                     /locus_tag="VXB71_001517"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0451611.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7488..8363
                     /locus_tag="VXB71_001518"
     CDS             7488..8363
                     /locus_tag="VXB71_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0451612.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8356..9171
                     /locus_tag="VXB71_001519"
     CDS             8356..9171
                     /locus_tag="VXB71_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0451613.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9164..9595
                     /locus_tag="VXB71_001520"
     CDS             9164..9595
                     /locus_tag="VXB71_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0451614.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9602..11269
                     /gene="recN"
                     /locus_tag="VXB71_001521"
     CDS             9602..11269
                     /gene="recN"
                     /locus_tag="VXB71_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0451615.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11271..11999
                     /locus_tag="VXB71_001522"
     CDS             11271..11999
                     /locus_tag="VXB71_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0451616.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12078..13901
                     /gene="lepA"
                     /locus_tag="VXB71_001523"
     CDS             12078..13901
                     /gene="lepA"
                     /locus_tag="VXB71_001523"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0451617.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13982..>14224)
                     /locus_tag="VXB71_001524"
     CDS             complement(13982..>14224)
                     /locus_tag="VXB71_001524"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451618.1"
                     /translation="KHSFEVVDETDEVSSKHGFEVVDETDEVSSKHGFEVVDETDEVS
                     SKHGFEIVDETDEVSNHTYGKATLTWFEEIFEEYKN"
BASE COUNT         4199 a         2600 c         3375 g         4050 t
ORIGIN      
        1 cttttatgaa atacagaaaa cgcttcctaa aacctaaagt ttgtgatata attatcaaga
       61 aaaaagattt aggagtttat tatggtttct tcagaattta tctcaaagat tgaatttgct
      121 tgcaataaga aagaaagtct ttatagtcaa agcaaattta agtatgcgat tcgttcgatg
      181 ttcgcaggtg catttttaac cttcagtact gctgcaggtg cagttggggc tgacttgatt
      241 aataaaattg caccaggtag tggacgcttc ctctttccat tcgtttttgc ttggggcttg
      301 gcctacattg tttttttgaa tgccgagttg gtcacttcaa acatgatgtt cttgactgct
      361 ggtagtttct taaaaaaaat ctcttggaga aaaacagctg agattttact atactgtacc
      421 ttgttcaacc ttatcggagc cttgatagca gggtggggct ttgctcattc ggcagcctat
      481 gcgaatctga tacacgatag tttcatctca ggtgttgttg agatgaagtt aggccgctca
      541 aatgaattgg tcttgcttga ggcgattttg gcaaatattt tcgtaaatat tgcgattctg
      601 tcatttattt tggtcaaaga tggtggtgcc aaactttggc ttgtgttgtc agctatttac
      661 atgtttgtat tcttaacaaa cgagcacatt gcggcgaact ttgcttcttt cgcgattgtg
      721 aaattcagtg ttgctgcgga ttcaattgcc aacttcggtg ttggaaatat gcttcgccac
      781 tggggtgtga ctttcatcgg aaactttatc ggaggaggcc tcttgatggg tcttccatat
      841 gccttcctca ataaaaacga agatacttat gtagattaag aaaatgagca cgattgagtc
      901 gtgctttttt cattttcaaa ataaggtaat agctatttct tatatcaaaa tatagaaaac
      961 tgatatttgt aaactataac tcaaggtgct acaatatcct taataaaatg atatggaggt
     1021 caccttatga cttgtgattt taaatctgaa actctacaac tacatgctgg tcaagttgtg
     1081 gctccagcta ctaagtctcg tgcagtgccg atttatcaaa caacattttt tgtttttgat
     1141 gacacgtagg aaggtgccga tctgtttgcc ttgaggaaac cagggaacat ttatactcgt
     1201 atcaccaatc ctacaacagc tgcccttgaa ggtggtgttg aagcgctagc aacagcatca
     1261 ggtatgactg cagtgactta tacgattttg gcgcttgccc atgctggtga ccatgtagtg
     1321 gctgcttcga ctatttacgg tggaaccttc aatcttttga aagaacccct tcctcgttat
     1381 ggtatcacaa caacctttgt cgatgttgat aatttggagg aagtagaagc agctatcaaa
     1441 gacaatacca agcttgtctt gattgaaacc ttgggtaact ccttgattaa tattccagac
     1501 ctggaaaaac tggcagagat tgctcataaa catcaaatcc cacttgtgtc agacaatact
     1561 tttgcaatac cttatttgat taacgtcttc tctcatggcg ttgacattgc cattcactct
     1621 gcgactaagt ttatcggtgg gcatggtaca actattggag gaataattgt cgatagtggt
     1681 cgttttgact ggatggcttc agggaaattc cctcaatttg ttgacgaggg ttcaagctgc
     1741 cacaatttga gctatactcg tgatgtgggt gcagtagcct ttattatagc tgttcgagtt
     1801 caattgcttc gtgatacagg tgcagccttg tcaccattca atgctttcct cttgctacaa
     1861 agacttgaaa cctcttcact tcgtgtggaa cgccatgtac aaaatgctga gacaattgtt
     1921 gattttcttg tcaaccatcc taaggtagaa aaggtaaatt atccaaaact tgcagatagt
     1981 ccttatcatg ccttggctga gaaatacttg ccaaaagatg tcggttcaat ctttaccttc
     2041 catgtcaaag gtggcgagga agaagcacgc aaggtcattg atcatttaga aatcttttct
     2101 gaccttgcaa acgcggcaga tgctaaatcg cttgttgtcc atccagcaac aaccactcac
     2161 ggtcaattgt cagaaaaaga cctagaagca gcaggtgtca caccaaacta aattcgtttg
     2221 tcaatcggtc ttgaaaatgt agaagatttg attgaagact tgcgcttggc cttggaaaaa
     2281 atttaaagta aaagaagata aacagtgggc ttcgactcac tgtttttgat tttccctcag
     2341 gcatgatata atggttaaag aagtctagaa agaggaacga tatgaacgaa atcaaatgtc
     2401 ccaactgtgg ggaagtcttt acagtaaatg agagtcagta tgccgaactc ttgtcccaag
     2461 tgagaacggc agagtttgat aaggaactac acgataggat gaagcaggaa ctggccttgg
     2521 ctgagcaaaa ggccatgaat gagcaacaga ctaaactggc tcagaaggat caagaaattg
     2581 cgcaattaca gagtcagatc caaaactttg atacagaaaa agaattggcc aagaaagagg
     2641 ttgaacagac aagccatgag gctctcttgg ctaaggacaa ggaagtacag ctcttagaaa
     2701 atcagttggc taccttgcgt ttggagcatg aaaatcaact gcaaaagacc ctttctgacc
     2761 tagaaaaaga acgggatcag gttaaaaacc aactactttt gcaggaaaag gaaaatgaat
     2821 tatgtttggc ttctgttaag caaaactacg aagcccagct caaggcagct agtgaacaag
     2881 tcgagtttta taaggatttt aaggctcaac aatctacaaa agcgattggg gaaagcctag
     2941 aacagtatgc agagagtgag tttaacaagg ttcgtagttt cgcctttcca aatgcttact
     3001 ttgagaagga taacaaggtc tcttcgcgtg ggtctaaagg ggactttatc ttccgtgagt
     3061 gtgatgaaaa tggagttgaa atcatttcta tcatgtttga gatgaaaaac gaagcagacg
     3121 gaacagagaa gaagcacaag aatgcagatt tttacaagga attggacaag gaccgtcggg
     3181 agaagaactg tgagtatgcc gttttggtga ccatgcttga ggccgataat gactacttta
     3241 acacagggat tgttgacgtc agccacgagt atgaaaaaat gtatgttgtt cgtcctcaat
     3301 tctttatcca gttgattggt ctcttacgta atgcggcgct aaattcccta aaatacaagc
     3361 aggagttggc cttggttcgc gagcaaaata ttgacattac gcattttgag gaagacttgg
     3421 atgcctttaa gctagctttt gctaagaact ataattcagc ttcgactaac tttggaaaag
     3481 ctattgatga aatcgacaag gccatcaaac gcatggaaga ggttaagaaa ttcctgacta
     3541 catctgaaaa ccaactccgt ctagctaaca acaaattgga agatgtctct gttaaaaaat
     3601 tgacccggaa aaatccaaca atgaaagcga agttcgaagc actgaagggg gagtagaaag
     3661 caaaaatgaa cggtattatc aacttaaaaa aagaagcagg aatgacctcg catgatgcgg
     3721 tttttaaact gcgtaagatt ttgggaacca agaaaattgg tcatggtgga accttggatc
     3781 cggatgtggt gggtgttttg ccgattgcgg ttggcaaggc gacacgcatg gtcgagttta
     3841 tgcaggacga gggtaagatc tatgaggggg aaattactct gggttattcc acgacgactg
     3901 aggatgctag tggggaagtg atcgcagaaa cccctgtttt gtctcccttg gatgaaaagc
     3961 ttgttgatga agcgattgct agcttgactg ggcctattac ccagattccc cctatgtatt
     4021 cggcagttaa ggttaatggt cgcaagctct atgagtatgc gcgtgctggt caggaagtgg
     4081 agcgtccaga acgtcaggtg atcatttatc aatttgagcg aacaagtccg atttcttatg
     4141 atggccaact tgcccgattc acttttcgtg taaaatgcag taaagggact tacatccgta
     4201 ctttgtcagt tgatttgggt gaaaagcttg gttatgcggc tcatatgtcc catttgactc
     4261 gtactagtgc tgctggctta caattagaag acgctctttc cttggaggaa attgctgaaa
     4321 aagtagaggc tgggcaatta gattttctcc atcctttaga gattgggaca ggtgaccttg
     4381 tcaaagtttt cctaactcca gaagaggcta cagaagttcg ctttggtcgt tttattgagc
     4441 tagaccaaac ggacaaagaa ctggctgcct ttgaagatga taaattgtta gccattctag
     4501 aaaaacgggg caatctctat aagccaagga aggtttttag ctagatcgtt taggaataaa
     4561 aatcgggtga tagataacaa ttgcttgata aaaccccata ctaatagtag aatggttttg
     4621 ggaattataa tattccaatt gttgcgagtt gtaggtactc aaataatcta tatagaaatt
     4681 tagaggtgtg aaatgaagca atttaaaatt ctttcagata aatatttaga gtccattaca
     4741 ggttctggtg ggaacttagg cccaggattt ggtgtgataa ttccatgatg cgaaatgagt
     4801 ttcgagaaag ggtggagcaa cttcttcaac aaaaagaaat aaatgaaaat agtgagttga
     4861 gtcacctgtt tcgtcttgct atacaaaatt tagacagaaa tgaaaaatac caatcggtca
     4921 tggccaattt gagtcaaggg ttgtcacttt acctcatgac gcatcattac caggcaccta
     4981 agtctgtcat tgattttggt ttatggattg ccaaagctcc tagccaggaa agagggagac
     5041 tggctttctt gcagatgctt gctcaaaccc tacagggctt tcgttaaaac tgtcgaacat
     5101 cagagggaag actctggtgt tttttgctga tgagactata aattttgtaa aaaatgtgat
     5161 agaatagacg acggataaaa taacggagga tagcatgcaa aatagaccaa tcattattgg
     5221 agtgacaggt ggttctggtg gtggtaaaac cagtgtttca agagccattt tatcgcattt
     5281 tcctgatgaa aagatttcca tgattgagca tgattcatac tacaaggatc agtctcattt
     5341 gacctttgaa gagcgtgtca aaaccaacta tgaccatcct tttgcctttg atacagactt
     5401 gatgatcgag cagattaagg aattgttggc agggcgtccg gtggacatcc cgacctacga
     5461 ctatacagag catacacgga gtagcaagac ctatcgtcag gagcctcaag atgtctttat
     5521 cgttgagggc attttggtct tggaggacaa gcgtctgcgc gatttgatgg atatcaagat
     5581 ttttgtggat acggatgacg atgtgcgtat tattcgtcgt atcaagcgtg atatggagga
     5641 acgtggccgt agccttgata gcgttattaa ccagtactta ggtgtggtca aaccaatgta
     5701 ccaccagttt atcgagtcaa ctaagcgtta tgctgatatc gtcattcctg aaggggttag
     5761 caataccgtg gctatcgacc tgttgacgac caagattgca aagattttgg aagaagctcg
     5821 aaacagcaaa taatcacatg tggaggcctt gcctcctttt tctatttttc cctcataatg
     5881 gtacataaat ggagattttt aggcatattt ttggtataat aatacccata aaagagcaag
     5941 taaatgaata gtaggtggag atggaaaagt atttatcggt aacaactttg accaaatatc
     6001 tgaaaatgaa attcgataaa gacccatact tggaacgggt ctatttaact ggtcaagttt
     6061 ccaactttcg taaacgacct actcaccaat atttctccct aaaggatgac catgcagtta
     6121 ttcaagcgac catctggtct gggatttatc agaaattagg gtttgacctg gaagaaggaa
     6181 tgaagatcaa tgtgattggg cgtgtacagg tctatgaacc aagtggtagc tactccatca
     6241 tcattgaaaa agctgagcct gatggggttg gggcgcttgc gattcagttt gaacaactta
     6301 agaaaaaatt gacagaagaa ggcctgtttc aagaacgctt caagcaagct ctaccccaat
     6361 tttctaagag aattggggta gtaaccagcc gtagtggagc cgttattcga gatattatca
     6421 cgaccgtcag caggcgattc ccaggtgttg acatccttct ttatcctacc aaggttcaag
     6481 gtgaaggggc tgcggaggaa attgctagaa atattgcgcg tgctaatcaa cgggacgatt
     6541 tggatttgct cattattggt cgtggaggtg gttctattga ggatctctgg gcctttaacg
     6601 aagaaattgt ggtacgagct atttttgaat ctcgtttgcc agttatctct agtgtggggc
     6661 atgagacgga tgtgaccttg gcagattttg tggcagatcg acgcgctgca acgccaacag
     6721 cggcggctga actggcaaca cctgtgacca agttggatgt attaactcat ttgcaaaatc
     6781 aggaaaaacg gatggcaacg gcagtccgaa atgttctatc taagaaacaa gaggctttga
     6841 aaaaatgcag tcagtctgtt atctttagac aacctgagcg cttgtatgac ggttatttgc
     6901 aacgcttgga ccaactgcaa ctgcgtttga aacaaagttt gcgaactcgg atttctgata
     6961 acaaacaatt agttcaagca agaactcatc aattagtaca attatcacct gttaccaaaa
     7021 tccaacgcta tcaagaccgt ttaggacagt tggacaagct cttaggtagc caaatggcgt
     7081 tagtttatga cgccaaggtt gctgaggcca agcgactttc ggaagctttg ctcatgttgg
     7141 atactagccg aatcgtggcg cgtggttatg ctattgtcaa aaaagaagag tccattgtag
     7201 attcggttga gagtttgaag aaaaaagacc aagtaacgct tttgatgcga gatggtcaag
     7261 tagaattaga ggttaaagat gtcaaaacaa aagaaatttg aggaaaatct agcagaactg
     7321 gaaaccattg tccaaagttt ggaaaatggt gaaattgctc tggaagatgc gattactgcc
     7381 tttcaaaagg gcatggtctt gtcaaaagag ctccaagcta cgctggacaa ggctgaaaag
     7441 accttggtca aggtcatgca agaagacgga acagaaagtg attttgaatg aaaaagcaag
     7501 aaaaattagc tcttgtcgag tcggctttgg aagattttta tggagaccag cagtttgcct
     7561 ctagtttacg ggagtctgtt ctctattcta ttcatgctgg tggcaagcgt attcggcctt
     7621 ttctcttgtt agaagttctg gaagccttgc aggttaccat caaacctgct cacgcgcagg
     7681 tagctactgc cttggagatg attcatacag ggagcttgat tcacgatgac cttcctgcta
     7741 tggatgatga cgattatcga agagggcggt taaccaatca caagaaattc ggtgaagcta
     7801 tggccatttt ggctggagat gccttattct tagacccata tgccttgatt gcgcaggcag
     7861 atttgccaag tcagattaag gtggacttga ttgccaactt atcccttgct tcaggtagtc
     7921 tgggtatggt ggcagggcaa gttttggata tggagggcga acaccagcac ttgtctttgg
     7981 aagaacttca gattattcat gccaataaga ctgggaagtt actagcctat cccttccaag
     8041 cggcagctat tatagctgaa ttgtcacctg aaatgcaggt gaagctgaaa actgtgggtg
     8101 aattgattgg acttgctttt caagtcagag atgatgtact ggatgtgaca gctagttttg
     8161 aggaaatcgg caagacacct caaaaggatc tgcaggcaga aaaatcaacc tatcctgccc
     8221 tgttgggctt ggaagagtcc attgcctttt gtaaccaaac cctggatcaa gctaatgaaa
     8281 aattagaaga aattgcccag cagcttccct ttgaaacaga atcgattgta agtgtagtag
     8341 aaagtttgag aatcaatggc taaggaaaga gtggatgtac tagcttataa acaggggttg
     8401 tttgaaacga gagagcaggc caagcgaggt gtaatggctg gcctagtcgt agcagtcctt
     8461 aatggagaac ggtttgacaa gccaggagag aaaattccag atgacaccga attaaaactc
     8521 aagggagaga aactcaagta tgtcagccgt ggtggtttga aactggaaaa ggccttgcag
     8581 gtctttgatt tgtcggtgga tggcgcgact acgattgata tcggggcctc tactggaggt
     8641 tttaccgatg tcatgctaca gaatagtgcc aagttggtct ttgcagtcga tgttggtacc
     8701 aatcagttgg cttggaaatt acgccaagac ccacgagttg ttagcatgga gcagttcaat
     8761 ttccgctatg ctgaaaagac tgatttcgag caggagccga gctttgccag tattgatgtg
     8821 agtttcattt cccttagtct gattttgcca gccttgcatc gtgtcttggc tgatcaaggt
     8881 caggtggtag cacttgtcaa acctcagttt gaggcaggac gtgagcagat tgggaaaaat
     8941 ggaattattc gagatgctaa gattcatcag aatgtccttg aatctgtaac agctatggca
     9001 gtagaggcag gtttttcagt ccttggcttg gacttttctc ccatccaagg tggacatgga
     9061 aatattgaat ttttagcgta tttgaaaaaa gaaaagtcag caagcaatca gatttttgct
     9121 gagattaaag aagcagtaga gagggcgcat agtcaattta aaaatgaata aaaaagagag
     9181 acttgaaaaa attagaagat tggtgacaga ttatcaaatc ggcacgcaag aagaaattgt
     9241 agaacatttg aaagaagcag gtatcactgc cactcaggcg acggtatccc gagatatcaa
     9301 agagttaggt attgtcaaaa ttcctttgag agacaacacc tatgtctacg aattaccaaa
     9361 atcaatcgta aaaagtctgc aactggctga agacaatatc gaatcggctg aattgatgga
     9421 taagatgatc aatctccaag ttattccagg aaatacggct tttgtaaaag ctcagttaat
     9481 cgatactttt gcagacaaga tttttagttg tttgactgat gatagctcga ttttagtcat
     9541 tgccagaagt ggaagtctag cagaggaaat ctttgaacaa gtaaaaaatt ggtaggtcta
     9601 tatgttactt gaaatttcga taaaaaactt tgccattatt gaggctattt ccctcaattt
     9661 tgaaaagggg atgactgtcc tgactggtga aacgggtgca gggaagtcga ttatcattga
     9721 tgccatgaat atgatgttgg gagctcgtgc gacgacagat gttattcgtc atggtgcacc
     9781 aaaggcagag attgaggggc ttttctcagt tgagaatagt cgtcttttac aggaaatttt
     9841 tgatgagcaa ggtttagaat taggtgatga aattatcatc cgtcgggaaa tcttgcaaaa
     9901 tggtcgtagt atcagccgtg taaatggtca gatggttaat ctgtctgttt tgcgagctat
     9961 tgggcaacat cttgtagata ttcatggtca gcatgaccat gaggagttaa tgcgtcccca
    10021 actgcatatc cagatgttgg atgaatttgg tgatgccgct ttttgggact tgaaagaaac
    10081 ctatcaaacg agttttgatg cctatcggaa aatgcgcaag caggttctgg aagtcaagaa
    10141 aaaccaacag gaacacaagg aacgtatcga aatgttggaa tttcaaatgg cagagattga
    10201 ggcagcaaac ttgcaggctg gagaagactt ggctctcaat caagagcgag ataaactcct
    10261 caaccacaaa aatattgcgg atacactgac caatgcctac agtatgttgg acaatgaaga
    10321 tttttcaagt ctggccaatg ttcgttcagc tatgaatgac atggaaagtg tcgaagagta
    10381 tgatcctgaa taccgtgaaa tttcaagctc tctgtctgag acctactatg ttttagaaga
    10441 cattagcaaa cgtttggaag ctatcattga ggaccttgat tttgatggca atcgcctgat
    10501 gcaggttgag aatcgtttgg acctccttca tactattact cgtaagtatg gtgggactgt
    10561 tgatgatgtt ttgctttatt ttgccaagat tacggaagaa tacaatctct tgacaggcaa
    10621 taatctttcg tctgaggaca tggaagcaga gcttaagaag ttggaagtca atcttgtcaa
    10681 tttggcaggt caacttgctt ctgctcgtca taatttggct cagcaactcg aagctgagat
    10741 taaacaagaa ctgcaagatc tttatatgga aaaagcccag tttcaggttc attttagtaa
    10801 gggaaaattc agtcgtgggg gaaatgaaat ggttgagttt tatatttcaa ccaaccctgg
    10861 agaagacttt aaacccttgg ttaaggttgc ttctggaggg gaattatctc gtctcatgtt
    10921 agccattaag tctgcctttt cacgtaaaga aggcaagact agcattgtct ttgatgaggt
    10981 ggatacggga gtttcaggtc gtgttgctca agctattgct cagaaaattc ataaaattgg
    11041 tcagcatggt caggttttgg ctatctccca tttgccacaa gtaattgcga ttgcagatta
    11101 tcaattcttt attgagaaga ttagtaatga ccattcaacg gtttcgactg ttcgtctctt
    11161 gacagtcgaa gagcgagtgg aggaagttgc caagatgttg gcaggtgatg atgtgacaga
    11221 agcagccctg acgcaagcca gagaattgtt gagaaacagg gagaaataag atgacagatt
    11281 attatgtaat tggagatgtt cacggaaaag ctgggatgct ggaagacctt cttaaaacct
    11341 gggatggtca gacccagttg ctctttctag gtgatttgat tgacagaggt gaggatagtc
    11401 accgtgttct tgaaatggtc aaggacttgg tggacaatca aggggctatc tgtttgtctg
    11461 gaaaccacga gtatatgttt ttgacttggc tagatgaccc agaagaaagt tatgaccatt
    11521 atcgtcgcaa tggtggagat acaaccatta actctatcct aggtcgtccc ttggatgcac
    11581 cagttgatgg agtagaagat gccaagcggg ttgccgctga agcgtcagac ttggtcgaat
    11641 tcattcgtca aatgccattt gtagtagaga cagacaagta tatatttgtt cacgcaggta
    11701 ttgatttgac tttggacgac tggcatgaaa caacagatta taaaaaagta tggcttagaa
    11761 aaccattcca cggagctgaa aatcatactg gaaaaaccat tgtcttcggt catacaccgg
    11821 tctatggttt gttacagcaa gaacgcggta catctgagct ttggactaca gaagatggca
    11881 agattggaat ggatggagga gctgtttatg gtggtgtcct tcacgggatt gtctttacag
    11941 accaaggaat gacagaacac cactttatcg aaaatgacgg ctttgtcgct gaagattagt
    12001 actcctagca gggtatggtc ttgtcaaaat atcaaaaaca atttataata aatagatacc
    12061 ctgaaaggaa gagaatcatg aacttagaag aattgaaaaa acgacagggg aagatccgta
    12121 acttctctat tatcgcccat attgaccacg ggaaatcaac tctagcagac cgcattttgg
    12181 aaaaaacaga gacggtttca agtcgtgaaa tgcaggccca gcttttggat agcatggatc
    12241 tagagcggga acgtggaatt actattaagt tgaatgccat cgagttgaat tacactgcaa
    12301 aagatgggga aacttatatt ttccacttga ttgacacacc agggcacgtt gactttacct
    12361 atgaagtttc acgttcgcta gctgcctgtg agggtgctat tttggtggtc gatgcggctc
    12421 aaggaattga ggctcaaact cttgccaacg tttatctggc tttggataat gatttggaaa
    12481 tcatgcctat cattaataaa attgacctgc cggctgcaga tccggagagc gtgcgtacag
    12541 agattgaaga tgtgattggt ttggatgcca gtgaagcagt tttggcttct gccaaggctg
    12601 gtattgggat tgaagaaatc ctcgagcaaa ttgtagaaaa agtaccagca ccaacgggtg
    12661 atgtgacggc gccacttaag gccttgattt tcgactctgt ttacgatgct taccgtgggg
    12721 ttatcctcca agtgcgtgtc atggacggag tggtcaaacc tggtgataag attcagctca
    12781 tgagcaatag taagaccttt gatgtggccg aagtcggtat ttttacacca aaagcggttg
    12841 gtcgtgattt ccttgcgact ggtgatgttg gttacattgc ggcgtctatc aagacggttc
    12901 aggatactcg tgtgggtgat accgttacct tggcaaccaa tcctgcggca gaaccattac
    12961 atggttataa gcagatgaat cctatggtct ttgcgggtct ctacccaatc gaatcaaaca
    13021 agtacaatga cctgcgtgaa gcgcttgaaa aattgcaact gaatgatgct agtcttcagt
    13081 ttgaaccaga aacatctcag gcacttggat ttggtttccg ttgtggattt cttggacttc
    13141 tccatatgga tgttatccag gaacgtttag agcgtgagtt caatattgat ctcatcatga
    13201 cagctccgtc tgttatttac aaagttaatt tgaccgacgg tgagtctatg gatgtgtcta
    13261 acccatctga gtttccagac ccaactaaga ttgcgaccat tgaagagcct tatgtcaagg
    13321 cgcaaatcat ggtaccacag gagttcgtcg gagcagtaat ggagctagct cagcgtaagc
    13381 gtggggactt tgtgactatg gactatattg atgataaccg tgtcaatgtt atctatcaaa
    13441 ttcctcttgc tgaaatcgtc tttgacttct ttgataaact taagtcttcg acacgtggtt
    13501 atgcaagttt tgactacgaa ttgtcagaat atcgcccatc taagctagtg aaaatggata
    13561 tccttctcaa cggagacaag gtggatgccc tcagctttat cgttcataag gactttgctt
    13621 atgaacgtgg gaaactcatc gttgataagc tcaagaaaat catccctcgc caacaatttg
    13681 aggttccaat ccaagcggct attggacaca agattgtcgc tcgtactgat atcaaggccc
    13741 ttcgtaagaa cgtacttgct aaatgttatg gtggtgacgt ttctcgtaag cgtaaactcc
    13801 ttgaaaaaca aaaagctggt aagaaacgca tgaaatccat cggatcagtt gaagttccgc
    13861 aagaagcctt cctcagcgtc ttgagtatgg atgaagaata agttatcaga aatgcctttc
    13921 cttgttcaca ggaaatttat ataagaatca atagtaaagc aggcttagat ggtctgcttt
    13981 tttagttttt atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg
    14041 tatggttact gacttcgtca gtttcatcta caatctcaaa accatgtttt gagctgactt
    14101 cgtcagtttc atctacaacc tcaaaaccat gttttgagct gacttcgtca gtttcatcta
    14161 caacctcaaa accatgtttt gagctgactt cgtcagtttc atctacaacc tcaaaactgt
    14221 gttt
//
LOCUS       DAVLAQ010000046        14052 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000046 DAVLAQ010000000
VERSION     DAVLAQ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.046"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(135..2693)
                     /locus_tag="VXB71_001525"
     CDS             complement(135..2693)
                     /locus_tag="VXB71_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0451619.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            3241..4441
                     /locus_tag="VXB71_001526"
                     /pseudo
     CDS             3241..4441
                     /locus_tag="VXB71_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4556..5359)
                     /locus_tag="VXB71_001527"
     CDS             complement(4556..5359)
                     /locus_tag="VXB71_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0451620.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(5640..6395)
                     /locus_tag="VXB71_001528"
     CDS             complement(5640..6395)
                     /locus_tag="VXB71_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0451621.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPCFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(6465..9116)
                     /locus_tag="VXB71_001529"
     CDS             complement(6465..9116)
                     /locus_tag="VXB71_001529"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0451622.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(9128..10090)
                     /locus_tag="VXB71_001530"
     CDS             complement(9128..10090)
                     /locus_tag="VXB71_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0451623.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(10092..10649)
                     /locus_tag="VXB71_001531"
     CDS             complement(10092..10649)
                     /locus_tag="VXB71_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451624.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(10636..10998)
                     /locus_tag="VXB71_001532"
     CDS             complement(10636..10998)
                     /locus_tag="VXB71_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451625.1"
                     /translation="MLAMEQAGFISHQEKLERLGVHYEISERTQTPILDACPLVLDCR
                     VDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKR
                     VDMKGSFIKKARKKDGKN"
     gene            complement(11498..11893)
                     /locus_tag="VXB71_001533"
     CDS             complement(11498..11893)
                     /locus_tag="VXB71_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0451626.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(11989..12243)
                     /locus_tag="VXB71_001534"
     CDS             complement(11989..12243)
                     /locus_tag="VXB71_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0451627.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(12253..13587)
                     /locus_tag="VXB71_001535"
     CDS             complement(12253..13587)
                     /locus_tag="VXB71_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0451628.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(13587..13820)
                     /locus_tag="VXB71_001536"
     CDS             complement(13587..13820)
                     /locus_tag="VXB71_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0451629.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13851..13928
                     /locus_tag="VXB71_001537"
                     /pseudo
     CDS             13851..13928
                     /locus_tag="VXB71_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4197 a         3109 c         2474 g         4272 t
ORIGIN      
        1 ttcattttaa gatatttcaa tctatttgtc aagtacttgt agaaattttt ttattttgtg
       61 tgcttcgaat gtgataatgt caacagtctc attaaaaaat gaaaatcata catagaaatt
      121 tttaaaaatt ttctctatcg taaacctgcc actagttcag aaactatact agctgattcc
      181 aaacgtaata tggtcatctc atctaccttc cctaataatg gcattgcacc ataccaaaca
      241 atagtcttat tcaccaaaag aataggcgtt actatttttg attgagtaaa agacacttta
      301 attttctggc tcttcaactg gtctagccat gctttatttg caaccgtctc tggtatacat
      361 atctcaattt gactaatcct aaattctttt agaaaattca tcagttttgt ctggtgcaca
      421 taaggtaaaa taagcagaca ttcctgtctt tcccctgcta agtcctctct caacaccttc
      481 tcatatctac tatcaacata aacgaattgt ttctcctcac cctcgatgac acgataatcc
      541 atctttcgat aagctacttg tcgtttctga aacatctttt ctaaataagg aacatgaata
      601 tccacataat cgaaaatacg caccaaagac ttatccttgt agtttctatg aatccgacct
      661 gcatactgaa ttaaattatt tttccaagaa aagggtgctg ccaagataag cgtgtccaac
      721 tgaggtaagt caaaaccttc gccaatgtat tttccagtag acaacaaaac aaacccttta
      781 tctaactgtt ctaacgtctc cagtaaactc gttctttctc ggactttggt ttttccgcta
      841 ataatgtaac agccatcaac ctctttctct ttcaataact tttcaaagac atctatctgt
      901 tgaattcgat taactaaaac caagatattc cgtccttctg ccacttgggc tagaatatcc
      961 ttgagaatca actgattcct cgctgagtct gtagcaatcc aatcactgag ctgtataaaa
     1021 ttacttgctt tggtcttttc aatctccaaa tgaccaaaag aagtgaatct taattgcaat
     1081 tgccgtttaa aatccgtttc cctcttatca gcagtatgga gtatctcacc aattctctga
     1141 aaaacaatag gctcatgacc attcttacgc tcaggcgtag ccgtcaaacc gtaaagatac
     1201 ttccctctaa actgagcaac aactttttca aacatcaagg cagagacatg atgacactca
     1261 tccacaatca tcatctcata ctcatccaaa agactttgac tattttccaa cttaaataga
     1321 gattgaatca taacgacatc aaccagttta ctcagccatt tcttagtccc accgtactgt
     1381 ccaacatagc cgattacctt ttcacgacct gatgccgtat aacggatagc ctcctcctct
     1441 tcgaaagtca aaaagcagtt taagcgatct agccattggt ctaagagttg cttattatgg
     1501 actagaataa ttgtttttgt tttccgttca gagataagag cagcacctaa aacggtcttc
     1561 ccaaaaccag tctccgcatg aagtaaacca ttttctttag aagtcatatc tgacagggct
     1621 aactcttgct caaaagtgag ttctccctta aattccacgc taatagacct ttgtaccttt
     1681 ctcctatctt ccacagatac ctgcttaaat ttatcttgca atggatacag caaacctctt
     1741 ggcaaccata aataatgatc ggattctcca aataaataca ttctctcagg aatttgatag
     1801 gttggctgtc gcatagcctg ctttaaataa aattcgggat tagaaaatga agccatattt
     1861 ttcaagaaaa acagtgtctt gggtgtcaca gacgattttt caagttggat catattggat
     1921 aagacgatct tcaactcctt gtccaattct tgcttgccta actcctcttg gattaacagt
     1981 gccactttag cagttgaaat cttctgaatt tcttgtagat acctccattg atcttcataa
     2041 ggctgaaact gttcatccac aaagaccgtt cgcccttgat gataagcttc tccttgaaaa
     2101 ggaagggaaa ttaaattatc aaatccacct ttaggaagaa catcctgatt tggaaacatg
     2161 cgatcaaaag aatcaaagga cagttgcata ctttcctgca tagccaattc taatagtttc
     2221 tttccaaaca ggcgagcctt tcgactcaga atcgcttcct caaagaagaa ccaaatatgg
     2281 agtccgtaac ccgaacgaga aatctctaaa tgggcttcca tctggcgttc cctggctatt
     2341 cttcgaatgg ttaaaccagc ttctttccaa tctccttcat ccaaatccag taccaaaaaa
     2401 taacagctat catctaagtg cataggaaag ataccgatag ctgcctcccc acgaaaatga
     2461 gatttcaaaa cggagttcgt caatgtctgg aaactccgtt tttcaggtgg caactgcttc
     2521 caaccataat cataggaagg aaaatactga attttccctt gttcattgat aaaattctta
     2581 gcataaacat cataacggcc agcaaacaca gaggtaaaca attgtaattt ttcttgcgtc
     2641 gtcaagcgac tactttgaag ttggaacatc tcctcgaact gagagcgttc cataacaaac
     2701 tgactcttgt ctttaagacg tttatagtgg aatgaaataa gatatgaaca aattgattag
     2761 gaaaatcaaa ttaatttata gaaatctttt agcagtcatg gcgtcctatt ccagattcaa
     2821 aatgctatac acaagaaaaa ctcactatcc ccattaaaag aagaaaagac atcaaggact
     2881 tctaccacaa ttccatccaa agacacaaaa acagccataa gagtcacctc cttgattcct
     2941 ataggctgat tataacaaga ctggctgaaa ttgtacatga aaataaaatc ctaatagtac
     3001 tcattttgta tgtgactaat attccgtctc gctccagaag gtacgaagta aatagagttt
     3061 aaacgagcag tctataaaat tcaaaaaacg catattatca agcgacctaa aactttgggc
     3121 tctataatat ttgtagtggg taaattccct atggatatta tggagcctat tttgggtaga
     3181 aaaaaagtcc cataagatct ataatgaaaa gcgacaaaac aactcattag aaagaatcat
     3241 atggaacaat tacattttat cacaaaatta ctagacatta aagaccctat aaaattcctt
     3301 accttgaaac gactggtatg cctactagaa ttctccttag aaaacgtcgt tttaagtgct
     3361 atcattgctt gaaaatgatg gtcgctgaaa cttctatcat caagaaaaat caccaaattc
     3421 ctcgtattat caaccaaaag attgcgcaaa agttaattga aaagatttct atgaccgata
     3481 ttgcccatca gctggccatt tcaacttcaa ctgtcattcg aaagctcaat gacttccact
     3541 ttgagtgtaa ttttagaaat ctgcctaaga ttatgtcttg ggacgttgaa acagtccggg
     3601 gagtgactgt ttcaatcggg agatggagat gagctttatt gcgcaagatt ttgaaaagct
     3661 cgatatcatc actgttcttg agggtagaac acaagctgtc atccgagatc actttcttaa
     3721 atatgataga gccgtccgat gtcgcgtcaa aattattact atggatatgt ttagtcctta
     3781 ctatgactta gctaaacagc ttcgctttca aatttctagg ctcaggctga aacagtctcc
     3841 cagactgttt cactcccgaa tgctaaaatc gttcttgatc gctttcatat tgtacaacat
     3901 cttagccgtg ctatgagtcg tgtgcgtgtc caaatcatga atcagtttca tcgaaaatcc
     3961 catgaataca aggctatcaa gcgctactgg aaactcattc aacaggatag ccgtaaactc
     4021 agcgataaac atttttatcg ccctactttt cgtatgcatt taaccaataa agagatttta
     4081 gacaagcttt tgagctattc acaagacttg aaacatcact atcagctcta tcaactcttg
     4141 ctgtttcact ttcagaataa ggaaccggag aaatttttcg aacttatcga ggacaatctt
     4201 aagcaggttc atcctatttt tcagactgtc tttaaaacct tcctcaaaga taaagaaaag
     4261 gttatcaacg cccttcaact acactattct aatgccaaac tggaagcgac caataatctc
     4321 atcaaactta tcaagcgcaa tgcctttggt tttcgaaact ttgaaaactt caaaaaaacg
     4381 gatttttatc gctctgaaca tcaaaaaaga aaggacgaaa tttgtccttt ctcgaactta
     4441 gcttttcttc aacccactac aattgacaaa gagccaaact ttgatgatat acgttttctt
     4501 gtgagaatat ttacttcatt tttgcctaaa attcaatgtt tactcagtat ttggattatg
     4561 aaaaatcaag gtctaaatct agatacattt tttctgaaga caaatcattt tgaccaccga
     4621 gcaagagatt ttcaaaaaaa gctgttaaaa actcaggacg tcgctgtaaa atctttgcat
     4681 tatctaatac caaggcatca cgaaaatatt tggaatgttg ctgaaatggt gtattatcaa
     4741 tatcaaaacc aaactcacga agatactgaa tcaaaaagac cgttactgtc cgagtgtttc
     4801 cttcgcgaaa tggatgaatc tgccagattc ctgaaataaa atgctggatt tgtttaacca
     4861 catccgcctg agttagtgtc gcatatgcaa cttgtttttc ctgattaaaa tcataatcta
     4921 aggtcatttg aatcatggag taatcagagt acacaacact ttcaccattc aaaacaggtt
     4981 cattctttgt gatattggtc tgacgaaatt gccccaccgg aatagagggt tcaaatatat
     5041 cttgaaacaa ctccttatga atagcaagta aggtcgcagg actaaagcta aagcctcttc
     5101 gagacaatag ttctacaata cgtagagaaa ccaagtctgc ctcttccgta cttgcatcaa
     5161 tagtatggtg ataagccgtt gcatcctcat aaacctgctc ataagtcagt tctccccggg
     5221 actgtttctc agccaaagat tccatatacg ctgatggcac tagattgtca actttctgca
     5281 gaccaaaacc tatccgccat aaatcacgct tcgcttcata agacaagttt ggattgtcaa
     5341 tgttgtaagt tggttgcata gaaatatcct ttcaattgtt tttcttcatt accagtaaat
     5401 cacgaaattg gttggaaact ggcttaaact ataaaaagtc ctcacaatag gttctatgat
     5461 atatatatat atatacttca tgtaaataat aaaagagtta taatcagcac tactgataaa
     5521 ttcaataccg atttcgccat cttaaaactt agtcaaacga ataccgttga tttccagttc
     5581 attaagtcgt tgacctgtca agacttctcg ttccttcaac tggaaaagtt aagggggaac
     5641 taatacaaat cctctacgct tctatattca atgatttcat ttttgataat attcttttta
     5701 aactcaaaat gttttaaagg attatcgatt aacactaact ttggaatatc atctagattt
     5761 gtgaccaagg ataaaataaa atccgattga aactccttga ctttttcaaa ttcttttgca
     5821 gttaaacgca cacgcccctt agattttcgg atacctttta cttcggcaag gtaagaatac
     5881 tcttggacat ctacctgaaa gtcatatcca tcaccataaa gacgggcatc ggttaactgt
     5941 ccaccttgga atttttcttc tttatcaaaa tgaaggataa aataattctc agcctccatt
     6001 cccgtttcct gtagacgttt gaatttagtt cgaactattg gtttttcaac gatggttatg
     6061 cctgttttct tcccttcact ggcaagtaac attttaacta tttcagcata actatgaaca
     6121 tcttcatttc caaacatcat atcaattaaa tctttacgaa aacgataaac ttcagctttc
     6181 tgccaccaac cttttcgatt attgtcaaaa caaggatcaa ataaatccat tctatttttt
     6241 acaactccag ttgtttcagc aattcccaga gaaaccacat agcgataaaa ctccgacttg
     6301 ctaaagcatt gaaattcttt tataaaaagc ttgtcaaact tggcaagacc gtagccaatt
     6361 aaatttaaca attcataatg agggtgtttg gacatcactt tctccatcaa tagatattga
     6421 tttcattata ccaaaaaaca cggctcatca ccgtgtttct gtgtttattt caccaacttc
     6481 ttcatctcat caatacgtgc tacggtcaca tcatacttgg cttggtagtc ggcttgtttg
     6541 tctttttctt tttggacaac ttctggttta gcgttggcga cgaagcgttc gttagagagt
     6601 ttcttaccaa ccatgtccag ttctttttgc catttagcga gttctttgtc gagacgagct
     6661 agttcttctt caacattgag gagatcggcc agtggcaaga agatttcggc tcctgtaata
     6721 acgcttgaca tagccagttc aggtgcaggg atggttgatg cgatttccaa gtgttctgga
     6781 tttgtaaagc gtttgatata gttgacattg ctgttaaaga aggcttccaa gtcactatcg
     6841 cttgtcttaa caaggatggt gataggcttg cttggtgcta catttacttc cgcacgcgca
     6901 ttccgaacag cacgaattaa gtctttgaga ctttccacac cagtgtgagc cgcaaggtct
     6961 tcaaaggcta gattaacagt tgggtatgca gctgtcacga tagaaccttc tgagatttgt
     7021 ccaaagattt cctctgtcac gaatggcatg attgggtgaa ggagacgaag gatcttgtcc
     7081 aaagtgtata gtagaacaga acgtgtgatg actttctctt cttcgttatc gctataaagg
     7141 acttccttgg tcaactcaac ataccagttg gcaaattctt cccaaatgaa gttgtaaagg
     7201 atatgaccag ccacaccaaa ctcgaactta tcaaagtttt cagtaacttt tgcaatggtt
     7261 tcgttgagat tgtggagaat ccagcggtcc gtcacattac cagcctcacc tgttgcaact
     7321 tttgtgacat tgtcatgcgc cacatccagc gtcaaacctc cattgttcat gaggatatag
     7381 cgagaaatgt tccaaatctt gttaataaag ttccatgaag catccatttt ctcataagag
     7441 aaacgcacgt cttgtcctgg cgcagaaccg tttgaaagga accatcgaag ggcatcggca
     7501 ccgtatttct cgataacatc cattgggtca atcccgttac cgagagactt agacatcttg
     7561 cgtccttgct cgtcacgaat gagaccgtgg ataaggacgt tttggaatgg ttgacggcct
     7621 gtgaattcca atgactggaa gatcatacga gacacccaga agaagatgat gtcgtaacct
     7681 gttaccaagg ttgaagttgg gaaataacgt ttaaagtctt ctgagtcgac ttcaggccag
     7741 cccatggttg aaaatggcca gagggcagaa ctgaaccaag tatccaagac gtcttcgtcc
     7801 tgagtccatc cgtcaccttc tggagcttct tcgccgacat acatttcacc atcagcattg
     7861 taccaggcag ggatttggtg accccaccaa agctgacgag agataaccca gtcgtggaca
     7921 ttttccatcc attgaaggaa ggtatcgttg aaacgaggtg ggtagaattc gaccttgtcc
     7981 tctgtgtctt ggttggcaat ggcgttctta gccaattggt ccatcttgac gaaccattga
     8041 gtagacaagc gtggctcaac tacgacacct gtccgttctg agtgaccgac tgaatggaca
     8101 cgtttttcga ttttgacaag ggcaccgatt tcttccaact tagcaacgac tgccttacga
     8161 gcttcaaaac gatccatgcc tgaaaattca aaggcaagct cattcatagt tccgtcgtcg
     8221 ttcatgacgt tgacttgtgg caagttatga cgttggccaa ccaagaagtc atttggatcg
     8281 tgggcaggtg tgattttcac gacaccagta ccaaactcag gatctgcgtg ctcatctcca
     8341 acgattggga tgagtttatt agcgattgga aggatgacgt ttttaccaat caagtccttg
     8401 tagcgcgggt cttctggatt aaccgcaacc gcaacgtccc caaacatagt ctcaggacga
     8461 gttgtagcaa cttcaagggc gcgtgaacca tcttccagca tgtaattcat gtggtagaag
     8521 gcaccttcta catccttgtg aatcacctca atatcagaaa gggctgtgcg agctgctggg
     8581 tcccagttga tgataaactc accacgatag atccagcctt tcttgtaaag gtccacaaag
     8641 accttacgaa cagcttttga caaaccttcg tcaagagtga aacgctcacg agaatagtct
     8701 acagaaagcc ccatcttgcc ccattgttcc ttgatggtag tggcatattc gtctttccat
     8761 tcccagacct tcgtcaagaa agactcacga cctaggtcat aacgcgtaat accctcacca
     8821 cgtaagcgct cctcaacctt agcctgagtc gcaataccag cgtggtccat acctggaagc
     8881 caaagggtat caaagccctg catgcgtttt tgacggatga tgatatcctg caaagtcgta
     8941 tcccaagcgt gaccaaggtg aagtttccca gttacgtttg gtggtggaat cacgattgaa
     9001 taaggcttag ccttttgatc gcctgaaggc ttgaaaacat ccgcatcaag ccatttttgg
     9061 taacgaccag cctcaacctc ggctggattg tatttagatg aaagttcttt agacatgtgt
     9121 gttctcctta attactttta ttgacaattt taaccaaacc aatttttgaa agttcaatat
     9181 aaatctcttc aatttcagca aatgctgcaa gtggtgacat agtataattt ccaggattat
     9241 atttaagatc atacttgctt atctttgaaa tataatacct agagtgtttc aattttaatg
     9301 attccaactt tgatttaata tctactaatg tattatggtt taactttaaa aacaacttat
     9361 tataattacc atagagctct gtaagagcat taaagtattc tttcactaga gctatagcgt
     9421 caatcttaga tgtttcttgg tttagtttta tcaactcccc tttcaatttt ttccatttaa
     9481 agttggaatt taaaagataa tctaaatcaa tatagaaatc tattataaca gtctcatcat
     9541 ctgggctaac agcttttacc tcatttattg gtaagtcagt atgttgcgaa taatttctca
     9601 aagaatggca aaatcgataa gcaaaattgg tatcatactg atagcttgca aaaccatgta
     9661 tacaatcaaa ctcctcacta tctttggaat atttttgttt aatttggttt tcgttaaaat
     9721 cgacaaacaa ttttccactg gataataaat gaatcatgaa acgatttaca tctgcctctt
     9781 caatttctaa ttcctttgac tcaagtttat ttttaatact taaaaaatcc gagacatctg
     9841 aaataaacaa ttcgaacata ttcttgattt tttgaaaatt cttttgaatc tcaaaaattt
     9901 ggtccgagac tgacattatt tccttggttg gttcaatatc agagatgaca atacgttttt
     9961 cattgttgtt aatttctaaa taagctaatc gctcgataat atcactatca tttaattcag
    10021 catactcaac atcaatttgg cgtaactgct tctcagatag agagcttact tcctctttta
    10081 catcgctcat cttattcctc ccactcgctc ttcagcaagc catatatcag actgtcacag
    10141 cggtttcctt gaacatcctt tcggtctctt atgcgagctt cgagggtaaa gccaagcttt
    10201 tccgcgactc gttgactttg aaggttatat ccaaagcaag ttagttcaat cttgtgaaga
    10261 cccaaatctt taaaggctaa gtcaatcaag gcacgcgcag cttctggcac ataacctcgc
    10321 ccccaatagt ctgagtgtaa ggtatagccg atttccatca catcatcttc atggcgatgg
    10381 ttgaaataga tagagccaac gatcttatcc gttcctttga cgacaatccc gtagcctgct
    10441 gggagatttt ccttttgatt acgctccgga agaatgtgct ccagataata aatctcatct
    10501 tccaaggtct tgactggagg aaaacctgct ggataggcga cctctggcaa actagcatag
    10561 tcaaagatat cctcagcatc cgccacagta cggactcgta aaacgagacg ttctgtttcg
    10621 attttatctg gcagctcagt tcttgccatc cttcttcctc gcttttttga tgaaactgcc
    10681 cttcatatct acacgcttgt ccagatagcg ataaacgcgc tgatatccat ctcccatgaa
    10741 ataggttggg gcaaacagtt gatttttaaa atgtcccttt tcatccagga gttctggggc
    10801 aacaagtcgc tcaagaatct tggcaaagat gtggcaaata ccgtcttcct caacaatcct
    10861 atctacccga caatctaaaa caagtggaca ggcgtctaaa ataggagtct gagttcgttc
    10921 agaaatttca taatgcactc ccaaacgttc caatttctcc tgatgactga taaaaccagc
    10981 ctgctccatc gcaagcatag aagtttcatc agaaatattc acagtaaatt tttgatactg
    11041 tttgatctac tctgcggcat tctctctcgc aacgactcca atcacaaccc aatctcctag
    11101 actataagag gaactacagg tcgtgatgtt atagccaaaa ttctaatctt gatatcctaa
    11161 aataaaaaca ggaaaaccat aatatagttt acttgtgtta aaagattgct tcataacaac
    11221 cccctttgac taagacgtaa aagaaaagcc ctgccatcta catgacaggg acgaatgtgt
    11281 ttatccgcgg taccacccaa tttcgggcag ttgcccgcaa ctctcgtctt taaagcaaaa
    11341 agacactttt atttcaattt ttcatccatt agcaaccagt tttgacacat ttgtggactt
    11401 ctcagcgccg ccactttctg taaaatgtgg gattcaaaac acctctaatg gctctattgt
    11461 agcaagattt tttcggaaat gcaaggctca agaaaaatta cttgaacttg atgccatttt
    11521 ctttcaattt cttgatggta gctgggccga ttcctttcaa gtcaaggagt tctttttcag
    11581 tccagttttt gaaatctgaa gcagacttga ttccttcatc atagaaagtc ttggcacgat
    11641 caagtggaag tccacccaaa tttgctgcaa aatcttctac agaattagct actttttgag
    11701 cttgctcttt ggtagcttct actgcttgtt caactttttt agaaacagcc ttaccagctg
    11761 cgcttgctga ctgttctgca cgcttcacga ctttttttgt ctcatctaca accttagtca
    11821 cagtacttga aaaggcacct gcgcgacgga ggccatttcg taattgtttt ttacgattga
    11881 gtttctttga catgataaaa tcctttcaat aaaaaatccc tgctctgaca aggatttaac
    11941 ataaacattc tatcaagatt ttagtgaaaa atcaagaatc tttctcgttt aataatttcg
    12001 ctcaccaaac aagccttctg gcaaatcatg gaatcccttg cctactttga agttttcaaa
    12061 cttaccaagc aagaactgat aagcatccaa gcgactctcg tagcgaatca tggcatcttt
    12121 ggcacgctcg tcctggtctt cttcgtaaac tttttggctt tccttgtgcg ccatgtcgtt
    12181 aatcatgatt tgggtattga cccaagcttc aaattccttc ataaattctt gttcgtaact
    12241 cattttttct ccttattcta atccacggaa atagtccgta tcaatctcac ggtagggctg
    12301 gatatcctga acgtattcca gtacaccttg gaattctccg ttttcatcgt gtactgcagc
    12361 ataggtgatg tggacaaact tgcctcgcga ctcagacttg aaccacattt catacttgtc
    12421 cttggtcccc tcacgaagtc ccttcatgat agccttgacc ttgtccaaat acttaggcgg
    12481 atgacagagt tcgacattgc gcccgacttg ggacggcgtc cgtttgaaaa tcatctcatc
    12541 agctggcgta ttgtcattgt aatactggaa aatatcttct ttattgacaa aggtaatctc
    12601 catagggaga tgattgagga tgagattggc ctgctcgact gaaagatagc cattaccaaa
    12661 agcctgttga ctatggcggt ccagcacagc ttccttttcc ttaggggtaa aggtaatggt
    12721 aaaatggcct tctggcgtat ctatgacttg ttgaacttga ccttctgccg tatctagctg
    12781 tacaggctcc tctgcaatct tttcctcaat aaagctctgt cgttctggca cccatttctc
    12841 tgacggacgg atgatggcat agccataggc atcgctctcc tccgcaatct gaagccagtc
    12901 atcctgagta aaagactcaa ggagaatcat gaggaggatg gactcttcct tgaaaatcat
    12961 actttcaaac tctgtcgcaa aagcttcaaa agcttccttt acactgctaa ttgacacttc
    13021 tggtagtgac ttggctgtcg ttagagctgt ttgaaagagt tccctaatct gatcatccac
    13081 tccccacata actttgggag gtgaatcgtg tccatagcgc tccatgatag gaaagaagag
    13141 ttcttcctta cgttggtaat ggatgtcaaa ttgacccaca agtcccatct gacgcaccaa
    13201 acccttacgc atctccgcca gcatttcctc gtcttccata gactcatagg tatctaacaa
    13261 tctacgaatg cgaatcaagg ccgcacggag agccagattt tcttctttga agacacgaac
    13321 tgggtgacct ggatgctcag tatctgaaac ttcgacacct ttgatagcat ttttaaaaag
    13381 attggcatgg acatcacaga gttccataac atcttcaaag gtgacacctg agtctgagtt
    13441 catcagctcg tgctccataa gggaaatctc aatggctgag acacccgcaa aggtcgcatc
    13501 aaaacgctcc tgaaccgact caggagaggc gccattatgc aattctaata aaatatcccg
    13561 taggacatga atccgttcat ctgccattag tctaatccaa tcacttcgta gccattcgct
    13621 tccagtgtgc gtacaatctt gtccatagga gttcctgcta gcttagaacc ttgtttaagt
    13681 gatactttac gaccaactgt attgcgcatt aagggattgg caaggggttt aaaacccaac
    13741 tccactagaa tttccaagac ttctggatgc ttgtccacca cttctgcaac aggaattgac
    13801 acatcgatga tattgtccat gacgacctcc attgtatgtt ctaatactca atgaaaatca
    13861 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca gtgctttgag gttgtagata
    13921 gaactgacga agtcagctca aaacaccgtt ttgaggttgt ggatagaact gacgaagtca
    13981 gctcaaaaca ccgttttgag gttgtggata gaactgacga agtcagctca aaacaccgtt
    14041 ttgaggttgt gg
//
LOCUS       DAVLAQ010000047        13818 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000047 DAVLAQ010000000
VERSION     DAVLAQ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.047"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(19..216)
                     /locus_tag="VXB71_001538"
     CDS             complement(19..216)
                     /locus_tag="VXB71_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0451630.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(291..1067)
                     /locus_tag="VXB71_001539"
     CDS             complement(291..1067)
                     /locus_tag="VXB71_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0451631.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1189..1935
                     /locus_tag="VXB71_001540"
     CDS             1189..1935
                     /locus_tag="VXB71_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0451632.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1948..2928
                     /locus_tag="VXB71_001541"
     CDS             1948..2928
                     /locus_tag="VXB71_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0451633.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3123..3443
                     /locus_tag="VXB71_001542"
     CDS             3123..3443
                     /locus_tag="VXB71_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0451634.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3489..3797
                     /locus_tag="VXB71_001543"
     CDS             3489..3797
                     /locus_tag="VXB71_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0451635.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3814..5112
                     /locus_tag="VXB71_001544"
     CDS             3814..5112
                     /locus_tag="VXB71_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0451636.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            5263..7701
                     /locus_tag="VXB71_001545"
     CDS             5263..7701
                     /locus_tag="VXB71_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0451637.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7720..8388
                     /locus_tag="VXB71_001546"
     CDS             7720..8388
                     /locus_tag="VXB71_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0451638.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            8406..9494
                     /locus_tag="VXB71_001547"
     CDS             8406..9494
                     /locus_tag="VXB71_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0451639.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            9949..12450
                     /locus_tag="VXB71_001548"
     CDS             9949..12450
                     /locus_tag="VXB71_001548"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0451640.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            12644..13339
                     /locus_tag="VXB71_001549"
     CDS             12644..13339
                     /locus_tag="VXB71_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451641.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13351..13767
                     /locus_tag="VXB71_001550"
     CDS             13351..13767
                     /locus_tag="VXB71_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0451642.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
BASE COUNT         4440 a         2141 c         2916 g         4321 t
ORIGIN      
        1 tacaaaaaga agaatagcct atttgactat tcttccgagt gatttcaatt tctttgggga
       61 aatatggaga tactttttaa atactttggc aaaatattta tagtctgaaa atccaacttg
      121 gtcagagata gcgcttaaag gggagttggg agattcagcc atcttatcta tagcttgttt
      181 caggcgatat tgtaagatat attcatttag agtcatgggg aagtcttctt tgataacctt
      241 atatagatgc ttgttatctg caaatagcta gagcatttca aggaaataaa ctagaaataa
      301 caattaatat ggtggttcag aaataccttt tgataatcaa taagatcttc aggatgaagt
      361 gcgttgattc catccatttc atatttccga tttaataaac gatatttgtt ttcaccaaat
      421 tgatgaaaag ggagtagttg aacttggtcg atatttaatg agttaaatag agtagcgaat
      481 ttttctgcat cctctaaact attgttaaaa ttaggaataa ctgggattct taaaacgata
      541 gttttatttt gagaaaaagc ataatgaatg tttttaataa tcatttgatt aaaaacccca
      601 gtcacttttt tatgttttat agaattataa tgttttaggt ctgtgtagat aaaatccaca
      661 tattgaatta aatcaataaa tttttcatga tcaacaaagg cagtagtttc aatggcagtg
      721 tgtatgtgat gttctttagc tgattttaag atggctttag caaattcaaa ctgagcaaat
      781 atttcacctc ctgataaagt taaacctcca ccggattctt cgtaaaattc tttgtctttt
      841 aatacctctg taataatttc ttctacagtc ttttcttcac cgactaaggt gaatttctct
      901 cgttgagcat ctttcatttt ttcaggtttc attctttgag attcaggatt agaacaccat
      961 ggacagcgca gaggacatcc ttttaaaaaa acagttgtac gaatacccgg gccgtcatga
     1021 attgaaaagt gttgaatatt aaaaataatt cctttagata tttccataag agttcctcct
     1081 cttcataagt ctatcctatc acaaaaacga aagaaaaaca attacgaacg aaagtttaat
     1141 ttgttgtttt ttgcttttta ttttggtaga ataaaacgga ggtgtaaaat gaaaagattg
     1201 gaacaaatta ttaaattagt atcagaatat gaaaagatcg acgttaatac attatcggaa
     1261 aaattaaatg tatcgaaagt aacgattaga aaagatttag ataaattaga gtcaaaaggt
     1321 ttattacaca gagagcatgg atatgctgta ttaaatagtg gagatgactt aaatgtacgt
     1381 ttgtcaatta actatgaaat taagagaaaa attgttcagg aagcagtaaa attggtgtca
     1441 gataatgaaa caataatgat agaatctgga tcgacctgtg ctttacttgc tgaggaaatt
     1501 tgcaagcaaa aaagaaatgt tacgattgta acaaattcat tttttatagc aaattttgtg
     1561 agagcttatg attcatgtcg tattattgtt cttggtggag agtttcagaa ggattcacag
     1621 gttactgtgg gacctttatt aaaagaaatg atacagactt ttcatgtgca tcaagctttt
     1681 gttgggacag atggttacga taaagagatg ggctttacag gaaaagattt aatgcgcagt
     1741 gaggtagttc aatatatttc agcagcgtcg gataaagtca ttgtactaac tgactcaagt
     1801 aaatttgata aaaggggtac agtaagaaga tttgctttaa gtcaagtcta tgaagtaata
     1861 acagacgaaa aactttctaa acaaaatata gctacattag aaaatgctgg gataatggtt
     1921 aaggtagttt cgtaagaggt taaatgtatg aatcaagata ggaataaact gctctctaaa
     1981 attgcttatc tgtattatat tgaaaactta aatcagtcac aaatagcagc aaaattagga
     2041 atttatagaa cctctattag tagaatgtta acagaagcaa ggaatgcagg aattgttaaa
     2101 attgaaatag agaattttga taccaatatg tttaagttgg aaaattatgt aaaagaaaaa
     2161 tatggtctgg aaagtttaga aattattcca aatgaatttg atgataatcc aacaatttta
     2221 tctgaaagaa tttctcaagt tgcagcaggt gtccttagga atctaattga tgataatatg
     2281 aaaattggct tttcttgggg gaaaagttta agtaatttag tagatttaat tcacagtaaa
     2341 agtgtccgaa atgttcactt ctatcctcta gcaggtggtc ctagtcacat acacgctaaa
     2401 taccatgtga atacactgat ttatgaaatg tctagaaaat ttcatggaga gtgtacattt
     2461 atgaatgcaa cgattgtgca agaaaataaa ttgttagcag atggtatttt gcaatcaaga
     2521 tattttgaaa atttgaaaaa tagttggaaa gatttagata tagctgtagt cggaattggt
     2581 gattttagca ataaaggaaa gcatcaatgg ttagacatgc ttacagagga tgactttaaa
     2641 gaattgacca aagttaaaac tgtaggagaa atttgttgtc gattttttga ttcaaaaggt
     2701 aaagaagtct atgaaaactt acaggaaaga acgatagcaa tctctttgga agatttaaaa
     2761 aatattcctc aaagtttagc tgttgcttac ggtgatacga aagtatcttc gattctttct
     2821 gtcttgcgtg ctaatttagt aaatcatttg attacagaca aaaatacaat tttaaaagtt
     2881 ttggaagaag atggggattt gacttttaga gagattctag gtgagtgaaa atgatagact
     2941 gatcagttta tcgttttttc tttttagtcg attgcacatt tgtgctcata taaacaaaaa
     3001 tagtttatct gttgtttttg gattgacaac tttattatgt agttgtattc tatagttaca
     3061 aaagaaaatt ttaaaatttc aaatgaaaaa agctttttac atagtgaaat gaggaggaat
     3121 ttatggaaat tattgttcca gatcaaatta tcatgggttt aattttatat gctggtgatg
     3181 cgaaacaaca tatttataaa gcgttagatt acataaaaaa tggtacatgt gaacggtgtg
     3241 aagaagaaat ccagttagct gatgccgcct tattagaagc ccataatcta caaacaaaat
     3301 tcttggcaca agaagcgtct ggtacaaaga cagaaattac agctctcttt gttcattcac
     3361 aagatcatct catgactagt atgacggaga ttaatttaat caaagaaatt attagtttga
     3421 gaaaagaact tcataaaaaa taatactaga gtattatcat tgttattaac atagaggagg
     3481 aaaacataat ggtgaagatt ggtttgtttt gtgcagcagg tttttctact ggtatgcttg
     3541 taaataatat gaaaattgca gcgcaagcta gtggagttga ggcagaaata gaggcgtttt
     3601 ctcagtctaa attagcggat tatgcgccaa atatagatgt tgcactattg ggtccacaag
     3661 ttgcttatac attagataaa tcaaaagaaa tttgtgataa gtgtgatgtt ccgatagctg
     3721 ttattccgat gatggactat ggtatgttag atggaaaaaa agtattagat ttggccctat
     3781 ctttgattag tgggtaagaa aaggagattt attatggcaa agatggatgt tcagaaaatc
     3841 attgcaccga tgatgaagtt tgtgaatatg cgtggcatta tagctctaaa agatgggatg
     3901 ttagcaattt tgccattgac agtagttggt agtttattct tgattatggg acaattgccg
     3961 ttcgaaggat taaataagag cattgctagt gtttttggag ctaattggac agagccgttt
     4021 atgcaagtat attcaggaac ttttgctatt atgggtctaa tttcttgttt ttcaattgcc
     4081 tattcttatg ctaagaatag cggagtagag gctttaccag ctggagttct atctgtatct
     4141 gcattcttta ttttgctaag atcatcttat atccctaaac aaggtgaggc aattggggat
     4201 gctattagta aagtttggtt tggaggtcaa ggaattatcg gtgctatcat tataggtttg
     4261 gtagtaggaa gtatttatac cttctttata aagagaaaaa ttgttattaa gatgccagaa
     4321 caagttccac aagctattgc caaacagttt gaagcaatga ttccagcatt tgtaattttc
     4381 ttactttcta tgattgtata tattttagcg aagtcattga ctaatggcgg aacattcata
     4441 gaaatgattt attctgctat tcaagttcca ttgcaaggtt taactggatc ttggtatggt
     4501 gcaattggaa ttgcattctt tatatcattt ttgtggtggt ttggtgttca tggacaatcg
     4561 gtagtaaatg gagtagtgac agctctgctt ttatctaatc ttgatgctaa taaagctatg
     4621 ttagcctctg gtaatctatc attagaaaat ggtgcacata ttgttactca acaattttta
     4681 gattcatttt taattctatc aggttcaggg attacgtttg gtcttgtagt tgccatgctt
     4741 tttgcagcaa aatcaaaaca ataccaagcc ttaggaaaag ttgccgcttt tccagcaata
     4801 tttaacgtaa atgagccagt tgtatttgga tttccgattg tcatgaatcc agttatgttt
     4861 gtacctttca ttcttgttcc tgtacttgca gctgtgatag tatatggagc tattgcaaca
     4921 ggtttcatgc agccattctc aggggtaaca ttgccttgga gtacaccagc tattttatca
     4981 ggatttttgg tgggtggatg gcaaggagtt attactcagc tggtgatatt agcgatgtct
     5041 acattggttt attttccatt ctttaaagta caggatcgtt tagcttacca aaatgaaatc
     5101 aaacaatctt agaggtattt gtgtgttact gttaaactca cacatttgtg ctaaaaatta
     5161 gagagttaaa atttttctag ttaaaagctt gaaaatttct ataaaaatcg gtattatatt
     5221 ttcgaaagaa ataaaaatat tttcgaaaga aaggtggtta cgatggtaaa tacagaagta
     5281 gcaagaacaa caatcaagac agaatatttt ggcagcctta ctgaaaggat gaacaaatat
     5341 cgagaagatg ttttaaataa aaaaccttat attgatgctg agagagcagt tctagcaaca
     5401 cgcgcctatg aacgatacaa ggaacaacct aatgtcctaa aacgtgcata tatgctgaaa
     5461 gaaattttgg aaaatatgac tatctatatt gaagaagaat ctatgattgg gggaaatcaa
     5521 gcttcttcca ataaagatgc tcctattttt ccggaatata cgctagaatt tgttctcaat
     5581 gagttggatc tttttgaaaa gcgtgatgga gatgttttct atattacaga agaaacaaaa
     5641 gaacaactta gaagtattgc tccgttttgg gaaaataata atttacgtgc tagagctggt
     5701 gccttattac ctgaagaagt gtctgtttat atggaaacag gattcttcgg tatggaaggt
     5761 aagatgaatt ctggagatgc tcacctagca gttaactatc agaaactttt gcaatttggc
     5821 ttaagaggtt ttgaagagcg ggctcgtaaa gcaaaagcag ctctagattt aacagatcca
     5881 gcaagtattg ataaatatca tttttacgac tctatattta tcgtaatcga tgctattaaa
     5941 gtatatgcaa agcgctttgt tgctcttgct aaaagtttag ccgaaaatgc aaatcctaaa
     6001 cgtaagaaag aattacttga gattgcagat atttgctcta gagtcccata tgaaccggca
     6061 actacttttg cagaagctat tcaatcagtt tggtttattc aatgtatttt acaaattgaa
     6121 tctaatggcc actctctttc atatggccgt tttgatcaat atatgtatcc atatatgaag
     6181 gctgatttag aaagtggtaa agaaacagaa gatagcattg ttgaacgtct gacaaatctt
     6241 tggattaaga caattacaat taataaggtt cgcagtcaat cacatacatt ttcttcagca
     6301 ggaagtcctt tatatcaaaa tgttacaatt ggtggacaga ctcgagataa gaaggatgct
     6361 gttaacccat tatcttattt ggtattaaaa tcagttgcac aaacccatct accgcaacct
     6421 aatctaactg tacgttacca tgcaggttta gatgctcgtt tcatgaatga gtgtattgaa
     6481 gtgatgaaac ttggttttgg tatgcctgca tttaataatg atgagattat tattccttct
     6541 tttattgcaa aaggagtatt ggaagatgat gcttatgatt acagtgccat tggatgtgtt
     6601 gaaacggcag ttccagggaa atggggctat cgttgcacag gtatgagtta tatgaacttc
     6661 cctaaggttc tacttatcac gatgaatgat ggaattgatc cggcttcggg taaacggttt
     6721 gcaccaagct ttggtcattt taaggatatg aagaactttt ctgaattaga aaatgcttgg
     6781 gataaaacac taagatattt gacacgaatg agtgttattg ttgaaaattc tattgattta
     6841 tcattggaac gagaagttcc tgatattcta tgttcagcat tgactgatga ttgtattggt
     6901 cgtggaaaac accttaaaga aggtggagca gtatatgatt atatatcagg attgcaagtt
     6961 ggaattgcaa atttgtcgga ttcattagct gcaattaaaa aattggtgtt tgaggaagaa
     7021 cgtataagcc caagtcagct ttggcatgca ttggaaacag attatgccgg agaagaaggt
     7081 aaggtcattc aagaaatgtt gattcatgat gcacctaagt atggtaatga tgatgattat
     7141 gctgacaaat tggttactgc tgcttatgac atttatgttg atgaaattgc taaatatcct
     7201 aatacacgtt atggaagagg gcctattgga ggaattcgtt attcaggaac atcttctata
     7261 tcagccaacg tagggcaggg acgtggaaca ttagcaactc cagatggacg caacgcgggt
     7321 acaccgttag cagagggttg ttcaccatca cataatatgg atcaacacgg ccctacatct
     7381 gttttaaaat ctgtttcaaa attaccaaca gatgaaatcg taggtggggt tctcttaaat
     7441 cagaaagtaa atcctcaaac gttagccaaa gaagaagata aattaaaact aattgctttg
     7501 ttacgaacat tctttaatcg tttacatggg taccatattc aatacaatgt tgtttccaga
     7561 gagacgttga ttgacgctca gaaacatcct gaaaaacaca gagacttaat tgttcgtgtt
     7621 gcaggatact ctgcattctt caatgttctt tctaaggcaa cccaagatga cattatagga
     7681 cgtactgagc atactttgta aaataaagag gttcttttta tggaatttat gcttgacaca
     7741 ttaaatttag atgagattaa aaagtggtct gaaattttgc cgctagctgg ggtaacttca
     7801 aatcccacta ttgcaaaaag agagggttct attaattttt ttgaacgaat caaagatgta
     7861 agagaattga ttggctccac accctctatt catgttcagg tgatttctca agattttgaa
     7921 ggcatcttaa aggatgctca tgaaattcga agacaagcag gagatgatat atttatcaaa
     7981 gtacctgtta ctccagctgg attacgtgca ataaaggtgc taaaaaaaga gggctaccat
     8041 atcactgcaa cagctattta tacagttatt cagggattat tagctatcga agcaggagcg
     8101 gattacctag ctccatatta taatagaatg gaaaatctga acattgattc aaattctgtc
     8161 attcgtcaat tagttcttgc tattgataga cagaactctc ctagtaagat tttggctgca
     8221 tcctttaaaa atgtagcaca agtaaataat gctttagctg caggtgcgca tgctgttaca
     8281 gcaggagcag atgtttttga atcagctttc gccatgccat ctatccaaaa ggcggttgat
     8341 gatttttctg acgattggtt tgttactcaa aatagtcgtt ccatttagat agagaggaaa
     8401 tacatatgag aatttttgct agtccttcta gatatattca gggggaaaat gccttgtttg
     8461 aaaatgccaa atcaattttg gatttgggaa attaccctat tctattatgc gatcagttgg
     8521 tttatgatat tgttggaaaa cgatttgaag attatctaca taggtatggt ttccatattg
     8581 ttctggcgct atttaatggt gaagcttctg acaatgaaat caatcgagtt gttgccttgg
     8641 ctgagaaaga aaattgtgat agtattatcg gtcttggtgg gggaaagacg attgatagcg
     8701 caaaagctat tgcagatttg attgaaaagc ctgttattat tgctccaaca attgcatcga
     8761 ccgacgcacc tgtatctgct ttatctgtta tttatacaga tgaaggtgca tttgatcatt
     8821 atctatttta ttctaaaaat ccagatttag ttttggttga tacaaaagtt atttcacaag
     8881 cccctaagcg tttattagcg tctggtattg cagatggttt agcaacttgg gttgaggcgc
     8941 gtgcggttat gcaggcaaat ggaaaaacta tgttgggaca acagcaaaca ttggctggag
     9001 ttgcaattgc gaagaaatgt gaagaaacgc tgtttgcaga tggtttacag gctatggcag
     9061 cttgtgaagc taaagtggtg acaccagcat tagaaaatat tgttgaagct aatactttat
     9121 tgagtggtct aggttttgaa agtggaggat tagctgcggc gcatgcaatt cataatggtt
     9181 ttactgcatt gacaggtgac attcatcatt taacacatgg tgaaaaagta gcttatggaa
     9241 ctttagtaca actattattg gaaaatagac ctaaagaaga acttgataag tatattgagt
     9301 tttacaaaaa aattggtatg ccaacaactc taaaagaaat gcatttggat caagttggat
     9361 atgatgattt aataaaagtt ggtaaacaag caactatgga gggtgagaca attcatcaga
     9421 tgccgtttaa gatttcgcct tcagatgttg ctcaagctat tatcgctgta gatgcctatg
     9481 taaattcaaa ataaacaata aggactactg ttttccaaat ggtagtcttt tattgatccc
     9541 cgtattgaat tctatagaag attgaaatag gatgagaaca aatcgattgg gaaagtaaaa
     9601 ttaatttcta taaatgtttt agcaattgtt tcgtactatt tcagattcag tctactatac
     9661 gttcttcata aatcaaaaag cgacataggt tgtcggctat ttattgtgaa tacattaatt
     9721 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcgtc
     9781 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
     9841 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
     9901 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
     9961 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
    10021 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
    10081 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
    10141 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
    10201 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
    10261 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
    10321 gtcaatacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
    10381 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
    10441 gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg ctatccagtt
    10501 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
    10561 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
    10621 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
    10681 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtctt ggctcctgaa
    10741 catgaattag tagacgctat cacaagttca gagcaagcag aagctgtagc agactataaa
    10801 caccaagcca gccttaagtc tgacttggtt cgtacagacc ttgctaagga aaaaactggt
    10861 gtttggacag gtgcctatgc catcaaccct gtcaatggta aggaaatgcc aatctggatt
    10921 gcggactatg ttcttgctag ttatggaaca ggtgcggtta tggctgtgcc tgcccacgac
    10981 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
    11041 ggaaatgtcg aagaagctgc ctacacagag gatggcctgc atgtcaattc agacttccta
    11101 gatggattga acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
    11161 tgtggtcagg agaaggttac ctaccgcctc cgcgactggc tctttagccg tcaacgttac
    11221 tggggtgagc caattccaat cattcattgg gaagatggaa cttcaacagc tgttcctgaa
    11281 actgaattgc cgcttgtctt gcctgtaacc aaggatatcc gtccttcagg tactggtgaa
    11341 agtccactag ctaacttgac agattggctt gaagtgactc gtgaagatgg tgtcaaaggt
    11401 cgtcgtgaaa ctaacaccat gccacaatgg gctggttcaa gctggtacta cctccgctat
    11461 attgacccgc acaatactga gaaattggct gatgaggacc tcctcaaaca atggttgcca
    11521 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta tgctcgtttc
    11581 tggcataaat tcctctatga cctcggtgtt gttccgacta aggaaccatt ccaaaaactc
    11641 tttaaccaag ggatgatttt gggaacaagc taccgtgacc accgtggtgc tcttgtggca
    11701 accgacaagg ttgaaaaacg tgatggttcc ttctttcata tagaaacagg ggaagagttg
    11761 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgttaaccc agatgatgtg
    11821 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgtttatggg accactcgat
    11881 gcttcgattg cttggtcaga agaaggtttg gaaggaagcc gtaagttcct tgaccgagtt
    11941 taccgtttga ttacaagtaa agaaatcctt gcggaaaaca atggtgctct tgacaaggct
    12001 tacaacgaaa cagtcaaagc tgttactgag caaattgagt ctctcaaatt caacacagct
    12061 attgcccaac ttatggtctt tgtcaatgct gctaacaagg aagataagct ttatgttgac
    12121 tatgccaaag gctttattca attgattgca ccatttgcac ctcacttggc agaagaactc
    12181 tggcaaacag tcgcagaaac aggtgagtca atctcttatg tagcttggcc aacttgggac
    12241 gaaagtaaac tggttgaaga cgaaatcgaa atcgttgtcc aaatcaaagg taaagtccgt
    12301 gccaaactca tggtcgctaa agacctatca cgtgaagaat tgcaagaaat tgctctagcg
    12361 gatgaaaaag tcaaagcaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
    12421 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
    12481 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
    12541 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
    12601 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
    12661 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
    12721 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
    12781 tttgctagct gtttatggcc cggatactcc tcgggagatg tggacctacc tttttcagga
    12841 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
    12901 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
    12961 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
    13021 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
    13081 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
    13141 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
    13201 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
    13261 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
    13321 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
    13381 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
    13441 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
    13501 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
    13561 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
    13621 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
    13681 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
    13741 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
    13801 atggtctagt attatata
//
LOCUS       DAVLAQ010000048        13131 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000048 DAVLAQ010000000
VERSION     DAVLAQ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13131
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.048"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            145..1491
                     /locus_tag="VXB71_001551"
     CDS             145..1491
                     /locus_tag="VXB71_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV0451643.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(1827..2678)
                     /gene="rgg"
                     /locus_tag="VXB71_001552"
     CDS             complement(1827..2678)
                     /gene="rgg"
                     /locus_tag="VXB71_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0451644.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            2802..3143
                     /locus_tag="VXB71_001553"
     CDS             2802..3143
                     /locus_tag="VXB71_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0451645.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            3201..3281
                     /locus_tag="VXB71_001554"
                     /pseudo
     CDS             3201..3281
                     /locus_tag="VXB71_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3397..5100)
                     /gene="ilvD"
                     /locus_tag="VXB71_001555"
     CDS             complement(3397..5100)
                     /gene="ilvD"
                     /locus_tag="VXB71_001555"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0451646.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(5333..6265)
                     /locus_tag="VXB71_001556"
     CDS             complement(5333..6265)
                     /locus_tag="VXB71_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0451647.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(6262..7119)
                     /locus_tag="VXB71_001557"
     CDS             complement(6262..7119)
                     /locus_tag="VXB71_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0451648.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(7123..8469)
                     /locus_tag="VXB71_001558"
     CDS             complement(7123..8469)
                     /locus_tag="VXB71_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0451649.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(8482..8766)
                     /locus_tag="VXB71_001559"
     CDS             complement(8482..8766)
                     /locus_tag="VXB71_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0451650.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(8770..10800)
                     /locus_tag="VXB71_001560"
     CDS             complement(8770..10800)
                     /locus_tag="VXB71_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0451651.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            10991..11998
                     /locus_tag="VXB71_001561"
     CDS             10991..11998
                     /locus_tag="VXB71_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0451652.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            12001..12201
                     /locus_tag="VXB71_001562"
     CDS             12001..12201
                     /locus_tag="VXB71_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0451653.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            12353..12535
                     /gene="rpmF"
                     /locus_tag="VXB71_001563"
     CDS             12353..12535
                     /gene="rpmF"
                     /locus_tag="VXB71_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0451654.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            12551..12700
                     /gene="rpmG"
                     /locus_tag="VXB71_001564"
     CDS             12551..12700
                     /gene="rpmG"
                     /locus_tag="VXB71_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0451655.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
BASE COUNT         4206 a         2769 c         2219 g         3937 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gctgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggttatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tattggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc caaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcgttac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgaaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt ttgtaagtta catctagttg agagaggtat gaatgatttg
     1681 ggagtatagc acttatgaat ttgcgaaacg attcttttga atatatgcaa caaacaaaat
     1741 gagcaaaaaa acgatagaac ttttgtaatg acctgagaga gggcaacagt tctatcgctt
     1801 caaatttttt cttggtttgc agatactcaa cattcggtcg tatttctata gtattcggca
     1861 gatttattac agccaagcat ctcaaaaata cggacagcat cctccatctt tttctgacct
     1921 tccttgactc taccttgctt gctatcaagg agaccttctg cccacagata aacaattcgg
     1981 aaataggtct cattttcctt gtagaaatgc tcttcgataa cacgtttaaa ataataggca
     2041 ttggtaaatt cttcacactc aatactagct aaaaagccat tcaatagtat agtataaaaa
     2101 aggtttcgat tgccagacat ttccattaga aaatcggatt tacgtaccat ttctcgtaca
     2161 tatctagtaa aaagagaaac agataaaaat ggagaactga ctgaaaataa attgagttca
     2221 tagattcccc agatctcggt agaaaacaaa taatcatgaa ggacttttcc ttcctctgct
     2281 gttaactcta ccctttcatc catgctcttc atataagact tgatcataat ggcatttaga
     2341 atatgtttct gtttgttgtg agaatgggca tgcttttgat actccctgcg atataagtcc
     2401 tcaagaggtg ctacattctt tggttccaag acatctgtaa tttcttttct caactcagaa
     2461 tctgtatcat actggaaacc tctcgccaga aagaggatct cctccacact ggcagatata
     2521 ttttccagag caaatagaaa cttttccacc gaaagctcac tctgacctgt ttcaaaacgg
     2581 gacaacatag acggcgaaaa ttgtcctccg gttgcttgtc tcagtgagat atttcttgac
     2641 tctcgtaatt gtctaaagac ttttccaatc tgctccatag acttcccctt gattccgtat
     2701 tttcttcatt ttatcatatt tttcagaaaa ttcatcaaaa acttgccaaa ttgtcagaat
     2761 tatgagaaaa tagaggatat ttatcacgtg gagggactgc tatgagagac gatatcaaaa
     2821 tcaatgaccg tgctttggcc ttgcaagacc aaatcatcga aaaactagag aaagtttttg
     2881 atacagatgt ggaattggat gtttacaatc taggtctgat ttatgaaatc aatctggatg
     2941 aaacggggct ctgcaagatt gtcatgacct tcaccgatac tgcctgtgat tgcgccgaaa
     3001 gcctgcctat tgaaatcgtg gcaggtctga aacaaatcga gggtatcaaa gatatcaagg
     3061 ttgaagttac ctggtcgcct gcttggaaaa tcacacgaat cagtcgctat ggccgtattg
     3121 cccttggact accacctcgt taagcaggcc aatcattttt aaagatgaaa aaagcaagcc
     3181 aaaaatggct tgctttttga tactcaatga aaatcaaagg gcaaactaga aaactagccg
     3241 caggttgctc aaaacactgt tttgaagtta tggatagaac tgacgaagtc agcccaaaac
     3301 actgttttga ggttgtggat agaactgacg aagtcagtaa ccatacctac ggcaaggcga
     3361 cgttgacgtg atttgaagag attttcaagt atgagtttat tttttacctg acttgtccat
     3421 attccagaag tctgtcacgg ctccgcgtga agcagatgat acgatatggg catatttacc
     3481 gaggacacca cggctgtaaa gtggtggcaa ggttgtttct gccttgcgtt tttcaagttc
     3541 ttcttcggat acggccatgg aaatttcttt ggtatcttgg tcaaccgtaa cgatatcgcc
     3601 ggtacggaga taggcaattg gtccaccatc ctgagcttca ggagcgatat gtccaacaac
     3661 cagaccataa gtaccaccag agaaacgtcc gtccgtcaag agggccacct tatctccctg
     3721 acctttacca acaatcattg aagaaagtga cagcatctca ggcataccag gaccaccttt
     3781 aggtccaaca aaacgaacaa cgactacatc gccatcaacg atttcatctg tcagaacggc
     3841 ctgaatcgca tcttcttctg agtcaaagac cttagctggc ccaacgtgac gacgcacttt
     3901 aacacctgat accttggcaa ctgcaccgtc aggagcaagg ttcccgttca agatgataag
     3961 cggaccatcc gcacgttttg gattttcaag tggcatgata actttttggc ctggagtcaa
     4021 gtctgcaaag tcagccaagt tttcagctac agtcttacca gtacatgtga tgcgatctcc
     4081 gtgaaggaaa ccatttgcca acaagtactt cataaccgca gggacaccac cgacttcgta
     4141 gaggtcttgg aagacatact gaccagatgg tttcaagtcg gccaagtgag gcacacgttc
     4201 ttgaatcgta ttgaagtcct caagtgacaa gtcaacattt gcggcatggg caatggcgag
     4261 caagtgaaga gtggcgtttg tagaaccacc gagagccatc gttacagtaa tagcatcttc
     4321 aaaggcttca cgagtcaaga tatctgatgg tttgagacca agttccaaca tcttaacaac
     4381 agcacgtcct gctgcttcga tatcttcttt cttatcagct gattcagctg ggtgagagga
     4441 tgaccctggc aaactcatcc ctagaacttc gatagcagtt gccatggtat tagcagtata
     4501 cataccacca caaccaccag ggccagggca ggcattacat tcaagacgtt tcacgtcctc
     4561 agctgtcatg tcaccgtggt tccattttcc gataccttca aagacagaaa ccaagtcgat
     4621 atctttacca tcaagatttc ccggtgcaat agttccacca taggcgaaaa tagctgggat
     4681 atccatatta gcaatagcaa tcatagatcc aggcatgttc ttgtcacagc caccgatagc
     4741 gacgaaggca tccacgttgt gaccactcat agccgcctcg atggagtccg cgatgatgtc
     4801 acgagatgtt agagagaaac gcataccagg cgttcccata gcgatcccgt ccgctacggt
     4861 aatggttcca aactgtacag gccaagcgcc tgcagatttg acaccttctt tagccagttt
     4921 cccgaaatca tgcaagtgaa tgttacatgg tgtattttcc gcccaagtcg aaatcactcc
     4981 cacaatcgat gtttcaaagt ccttatctgt cataccagtc gcacgaagca tagcacggtt
     5041 aggtgattta accatgctgt catagatgct actgcggtga cgtttatcta attcagtcat
     5101 cttatccctc ccatttcagt ttttactatt atagcacaat ttaaaggcaa tgaacagaat
     5161 aaaattcttg aattttcaga aaattctata cgcatgtgaa atatttaaaa ttaaaaacaa
     5221 caaagcggat tagtgcactt tctgatgacc agaatatgct ttttaatccg ctttctttaa
     5281 ataacgtact gtaattttta cagaaattct ttcagataag tgtatttaac atctatcttg
     5341 cattataaat ttctagaacc ttctctttta tattcgattc actcaaacca tactcattaa
     5401 gaagataatc cattttccct acttgaccga atctttcttg aacacccatc cgatgaattt
     5461 ttgttattcc atcatcagag aataattcac ataaagcact gccaattcca cctatctgat
     5521 tgtggttttc tacagtaaat atagtttttc cacttaacat tgtttttatc tgttctggta
     5581 tcggtttgat tctaaataaa tctatcacac ttactgaata acctaattta gacagttcat
     5641 ctgcaactcg aatacttgga gcaaccatta taccagaagc aacgattaca agatcttcac
     5701 catgccttaa ctcaatgtag cctttagaaa aatcttctcc accttgatac acaggaactg
     5761 gagcttttct aattgttcga atatatttta gtccttttaa gtctaatgtc tggttcaata
     5821 tttcacgaaa ttggatatca tcagttgctt caaaaatgat cgatttagga attaaacgta
     5881 acaatccaat ttcttcaaat ggcatatgtg tcccaccatt catttctgca gttactcctg
     5941 catctgatcc aatcacagtg gcatccaatt gtgcgtatcc aagagaaata aataattgat
     6001 caaatactct tcgtgaagca aaaggaccaa atgtatgaag ataaggtcta aacccctgaa
     6061 tagacaagcc tgctgcaagg ccgaccattt ctgcttccat aatcccaaca ttcacataac
     6121 ggtctccaaa gtccttttca agattatgag tagccatcga acttgacaaa tcggcttcta
     6181 agactactat atcagaatca ctttgattag cctctaaaag gaagtctcta tatacatgcc
     6241 gtaattcttt cgtgcttctc atcattctgt ttcctccaat tcctgactta atctttctac
     6301 aactgaggtt aacatttgtc tctcctctac agtagggcga agatgatgat tggatttcat
     6361 ttcttccagc tcttgaaccc cttgaccttt aatagtatct aatacaatgc acttaggtga
     6421 tgaattattt gactgtttta attggacaat cccttcataa atttctctaa tatctgaacc
     6481 cttgacccta atggattcaa atccaaatgc tgaaaatttt tctacgaaat cacctggatt
     6541 acaaatatcc tttgtaaaac catctaattg ttttttgtta tcatcaacaa atacaattaa
     6601 gttggataac tgttgatgag aagcaaactg tatagcctcc caacattgtc cctcatttaa
     6661 ctcaccatct ccaacaatag cataagtata aaagggactc tttcttattc tctgaccata
     6721 tgcaagtcca gttgcaacac taattccttg tcctaaagag cccgttgtca tatctatgcc
     6781 tggcgttaga tttctatcag gatgagacgg taatttggtt ccatttgtat ttaaagaata
     6841 taagaattct ttgtcaaaga aaccattcaa atagagtgta ctgtatagag ctggtcctcc
     6901 atgacctttt gataatatga aataatctct atctcgtgct gcaaatattt ctggagtcat
     6961 tggcattatt tcaccataaa gcactgctaa aacttctacg atagacagac ttcctccgta
     7021 atgtccgaat ccaagatgat tcaatgttct aagagtattt aatcggatgt tagtcgcaaa
     7081 ttttcttaac ccatcttctc tatttttact taaaatcatc ccttattcct cctttgcaga
     7141 tggcttttta ataaaggata ctccaaacat aactgctaga ataagaacaa gaccaatcac
     7201 aatgcctgct tgtgagccaa attgatttaa cattcctaaa ataattcctg atagaccaaa
     7261 atctgcatct gagaaagttg atccttggaa accaagtcct cccaaaactg gcattaaaaa
     7321 gactggaaga aaactgatta aaataccttg taaaaatgct ccaatagtgg ctccacgaac
     7381 accaccagat gcattcccaa tgacacctgc agtcgctcca cagaagaaat gaggcacaac
     7441 acctggtaag ataacaaccg ttcctgaagc aatcataatt gccatactta ctaaaccacc
     7501 aataaaacta gagataaatc caattagaac tgcattgggt gcataagtat aaacaatcgg
     7561 acaatccaaa gcaggttttg aattaggtac aagacgctct gaaatacctt taaaggctgg
     7621 aacaatttcg cccaaaataa ggcgaacacc tgctaaaata acaaataccc ctgctgcaaa
     7681 ttgacctgct aattgtaaag cataaactag accacttgta ccactactga tttctttttc
     7741 tatatattct gaccctgcaa agatagctac aataatgtaa ataactgcca tggataaagt
     7801 aatactaaca gtactatcac gtaaaaaagc taaactcttt ggaaatttaa tgtcctctgt
     7861 tgattttgat ttgtcaccga taaggctacc agtaaaacca ctcaaccaat atcccaaaga
     7921 actgaaatga cctaaagcca ccttgtcatt tccagttaat tgaaccatat atttttgaac
     7981 aaatgctggg gaaatactca taataatacc gagtgctaat cctcctagta agataagagg
     8041 caagctagta aagccagcaa ctgataaaat gaccgcaatc atacatgcca tatatagagt
     8101 gtggtgccct gttaaaaaaa tatatttaaa tcgagtaaaa cgagcgatta agatattgaa
     8161 caccatgcct gcaaacataa tcagtgcagt agctgagcca tatgttgtta aagctacagc
     8221 tacaattgct tcattattcg gcacaacgcc agataaatga aaagcatgct caaacatggt
     8281 accaaatgga tttaaagaat tttgtacaat tcctgcacca ccagatacaa ctaagaaacc
     8341 aacaaaggtc ttaattccac ctttaataat atcaggtaat ttcttcttct gaagaactaa
     8401 tcctaaaatt gcaattaaag ctactaaaat agctggtgta ctaacaatat ccaatatgaa
     8461 cttcatcatg acgctagcct cctatataag tcctttttct tcacaaagtt tagtaattaa
     8521 ttctcgtagt tcatccatat caataatact atttaagata cgaacatctc caagatgact
     8581 agctgaatca gctagatcac gaccaacaat ccaaatatca gctgcatttg gatctgctcc
     8641 acctaaatca taatgttcaa cttctacatc tgaaacattc aaatcactca atacagattc
     8701 aatattcatc tgtaccataa aacttgaacc taatcctgaa ccacaagctg taccaatttt
     8761 taacattatc taatcctcct gtttaattat cattttaatg tcatcatagt tttttgatga
     8821 tattaaagtt tgaacatgat ttttatctct taaaattgtt gttaaatgtg acaaagcctt
     8881 taaatgactc tcattatcaa tggctgcaat acaaatcaac aatcttacct cttgttctgg
     8941 attatccaat aaataaatcg gttcttccaa aactaacatt gacattccta tttcattcac
     9001 accttcatct ggccgagcgt gaggaattgc tactcccttc cctaaattaa taaaaggccc
     9061 aaactcttct actttttgaa tcattgcctc agggtagttc tcagttatct tatcttgatc
     9121 caaaagcggt ttagctgcta aacgaatcgc ctccttccat cctaattttt gcgaactaac
     9181 ctgataggtt tctttggtaa tgagttgttc tagcactggt acaatttcct ttctatcatt
     9241 tttttggtaa agataattct ttaacgccaa tcttaattcc aattcttgtg taataattcc
     9301 atatcttttg acaatattca gaatttgttc aatctcaaaa tccccatact ctaaattcgg
     9361 aaaatctttt aacactagtt ctactagttg tattgcttgc tcttcagtca tcataaccga
     9421 aactagataa tttggctttt ctgtctccac ctttatggta gaaaaaacca tatcatagtc
     9481 actactagct ttcacctgta aatcatcaat ctttgaggtt cctataaact caatttgagg
     9541 aaataatgct aatagattct cttttaacat caatgaagaa ctaacaccat taggacaaat
     9601 gattgctgct ttataccatt tttgaggcaa agtatctgct ttctttaaat aacctccgaa
     9661 atggataaca aaatatgctg tttcactatc aggtatggga ttgtcaatag cgtccatcaa
     9721 gggcatcaaa gaatctttga ctaattcaaa taaatcagga taatattctt taacatgcaa
     9781 tacatattca tttgaactag gtaggccgaa ctttaatcta tagtaagccg gtataaggtg
     9841 gcggcgaaga ttttctctca atccttccct ttgtttaaaa tgtaacaaag aaatatcttc
     9901 cattctactt ataatagcct ctgttaattg attaaagtaa accggagcaa catctacttc
     9961 accttcaaag caacttgata ataaaactgt gatatagcga taatcatcct cagaaaacac
    10021 cgtatctata attcccaaat caaccactgt atccaataaa atagtggtta tatcttgaat
    10081 aacaggagat actaatgtct ctgaaagaca tactctttca acatcccttt gatacctaca
    10141 cagaatgaat actaaaccga aaaggcaaac ttttaattga ttaacaatag gtactagttg
    10201 tagcttctca taataatctt taactacctg atttatcaaa tcataagtta atgaataccc
    10261 ccaactggat aaaacataat ccaaacccca aatccctatg gaggattcca gcaactcact
    10321 aaccatttga aaagctaagc ggtgcttatt ccactctgaa ccgtgtaaag tataaccttt
    10381 tgctctactg taccctagct ccaaatcatt atctaacata atctttctta atgattgaat
    10441 atcagataag gttgtattct tacttacttt caaaaagtct tggtaatgat tattcgatat
    10501 aaaatctaat cggcaaaaag tgtaaagata gattaaagct aagcgagtcg actttggtaa
    10561 aaccaattca tccgacttaa taatatctgt caaagactgc ttcgtacgat ttgataaact
    10621 atagcgacct tgttttttat ccagcactat ccctttatta gctagataag gcactaaata
    10681 atctattcct tctttgactt cctttatagg taagctcacc ttaacagata attcatataa
    10741 tgatagctca caatgatcca tcaaagtcat caaaataact agtgctctat aatcaaacat
    10801 ttctcttcct ttctaactac aattatagtg taaaaattat aagaataaaa gagtatttga
    10861 gcacaatata atctcacctt ttaaaagaaa ttattgggct gaaagttttt agtgattatt
    10921 ttcaactttc tattgacttt taaaaacaaa gtgatatcat ttagatatca aataatggga
    10981 ggtcattctt atgactgaaa aactaatcaa ttcaaaacca aatggtgtat tcgcattgat
    11041 tctcattgag ttgacaatcg tacttggtgt ctttatattt ataatgggtg ttggttcgga
    11101 aaacattttt ggaattatta tcggaccttt actaatcgta attgcaggtc tagctcatgc
    11161 tggtttaaaa gttgtcaaac ctcaggaagc tctggttctg acactctttg gtaactatac
    11221 aggtaccatc aaagaacctg gtttttactt tgtcaatccc ttcagcgtag cagtcaaccc
    11281 tgcaaaccac actcgacttg gacaaagtgg tgatgttagc acaaaatctc cttttttagg
    11341 agctaaatca tcaaatgaca atgatgtaaa tcttgaaatt ggcaagaaac agatttccct
    11401 caaagtcatg accttgagca attctcgtca aaaaatcaat gattgcttag gaaaccctgt
    11461 agaaatcggt atcgcggtaa cttggagagt tgtcgatacc gctaaggcag tcttcaacgt
    11521 tgataactac aaagaatatc tttcattgca atgtgatagc gccctccgta atattgtccg
    11581 catctatcct tacgatgtgt ctcctaatgt ggatactacg ggtgacgggc aagcagatga
    11641 aggtagtctc cgtggctcta gcgaaattgt tgctaaccgt attcgtgaag aaatccaaag
    11701 tcgtgttgag gatgctggct tggaaatcct tgaagcacgt atcacttacc tagcttatgc
    11761 tccagaaatt gctgccgtta tgcttcaacg ccaacaagca tctgccatta ttgatgcacg
    11821 gaagatgatt gtagatggtg ctgtaggaat ggttgaaatg gcactagaac ggctcaatga
    11881 aggggaattg gtagaacttg acgaagaacg aaaagctgcc atggtttcaa atctccttgt
    11941 cgttctttgt ggcaatcatg atgcacaacc aattgtcaac acaggaagtc tttactaaag
    12001 atggctgaag ctaaaaaaaa gcagatcccc cttcgactct caacaaagtt atacgctgca
    12061 ctcgcatcat gggcagaaga cgactttcgt tcagtcaatg ggcaaatcga atatctcctc
    12121 acagagtgtg tcaagcaacg gaagaaagac ggaaaatacg tatcagaaac cattgacgaa
    12181 ccatttgaga ttgatattta acatcttctc ctgtctgaca agtcggacag gagaattttt
    12241 tcatcttttt ttgtcaagta actttacttt acaaaaaaaa tgtgttatcc tagtatggtt
    12301 gatgaaaatc agtagattga atcgaatata aatacctaaa ggagaaatca aaatggcagt
    12361 acctgcacgt cgcacttcaa aagcgaagaa aaacaaacgt cgtacacact acaaagtaac
    12421 agctccatct gtaaactttg acgaaactac tggagattac tcacgttctc accgtgtatc
    12481 acttaaagga tactacaaag gacgtaaaat cgctaaagct gcatcagctg aataatagaa
    12541 gggagatacc atgcgcgtaa atattacact tgaacacaaa gaatctggtg aacgcttgta
    12601 ccttacttct aaaaacaaac gtaacactcc agaccgcctt caattgaaga aatactcacc
    12661 aaaacttcgc aaacacgttg tgtttacaga agttaagtaa gcattcaata cgaatcaata
    12721 cagaagaaaa acgcttgatc agcgtttttt ctttttgtta atttcactat attgcaaggg
    12781 aaatcattcg aatgactaca tttttcacta ccttttttga aataagaata cggattcgga
    12841 cgattaaaag taagagaaac tcaaatgtaa gttggggttc cttttttgta tatttttcaa
    12901 ataacgcctc tacactattt gtagcaaatt caccaactac agttgtatct tagttaaaat
    12961 aagttagaat atgtaagtga gtaccagata taccaagaca tcgtcaccat ctaaggtata
    13021 ttcaaaatac aaaagttgac caactagatt tctgaatatc cttatatatc cattcttaaa
    13081 attggtttaa atagcgtagt cttttaaact agttttgaga atccaaaaaa t
//
LOCUS       DAVLAQ010000049        12761 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000049 DAVLAQ010000000
VERSION     DAVLAQ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.049"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(391..2118)
                     /gene="ezrA"
                     /locus_tag="VXB71_001565"
     CDS             complement(391..2118)
                     /gene="ezrA"
                     /locus_tag="VXB71_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0451656.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2200..4146)
                     /gene="gyrB"
                     /locus_tag="VXB71_001566"
     CDS             complement(2200..4146)
                     /gene="gyrB"
                     /locus_tag="VXB71_001566"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0451657.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4161..4724)
                     /locus_tag="VXB71_001567"
     CDS             complement(4161..4724)
                     /locus_tag="VXB71_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0451658.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4809..5363)
                     /locus_tag="VXB71_001568"
     CDS             complement(4809..5363)
                     /locus_tag="VXB71_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0451659.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5374..6597)
                     /locus_tag="VXB71_001569"
     CDS             complement(5374..6597)
                     /locus_tag="VXB71_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0451660.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6634..9084)
                     /locus_tag="VXB71_001570"
     CDS             complement(6634..9084)
                     /locus_tag="VXB71_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0451661.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9284..10213)
                     /locus_tag="VXB71_001571"
     CDS             complement(9284..10213)
                     /locus_tag="VXB71_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0451662.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10353..10640
                     /locus_tag="VXB71_001572"
     CDS             10353..10640
                     /locus_tag="VXB71_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0451663.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10674..12008)
                     /gene="ciaH"
                     /locus_tag="VXB71_001573"
     CDS             complement(10674..12008)
                     /gene="ciaH"
                     /locus_tag="VXB71_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0451664.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11998..12672)
                     /gene="ciaR"
                     /locus_tag="VXB71_001574"
     CDS             complement(11998..12672)
                     /gene="ciaR"
                     /locus_tag="VXB71_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0451665.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3876 a         2728 c         2272 g         3885 t
ORIGIN      
        1 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg
       61 gagatttttc aatagacttc gttattggac ggttaccaag ttactcaaag tacagatttg
      121 aagctgcaga taagactgac gaaatcactt taatactaaa tgaaaatcaa aaagcaaact
      181 aagaagctag cctcaggctg tacttgagta cggtaaggcg acgctgacgt gatttgaaga
      241 gattttcgaa gagtataaaa cactgttttg aggtggtgga taaatcggct gggtaaaaac
      301 tcaatctcag gagaaaatga agtaaatctc cccacaacta tagaaaaaga tttgattctg
      361 ctcctcacac aataaaatct ttttctttta ttaaaaacga atcgtttcac gtgttttctc
      421 atatgaggta acaaagcgat tggttacacc aggctctgcc acttccaatg cttgagaaat
      481 cttgtcaaat gaagcgtgat aatcaaattc tttttcaaaa atatctaaag cttcgttaaa
      541 tgcttcttga atgcgttcat caaatgagcg atagcggtta gaatattgca agagttgctc
      601 tgtcaaagtt gcatattgta caatattata agtttccgtt tctaaagctt ccatatcatt
      661 cgttgcaatt tcaagaactc gggtaacaga ttcaatgtta atcatttttt gttctaactc
      721 aaccattaaa tcctcggtat tattgcttgc cgtaaagaat aacttcaaga aagtttgtgg
      781 aatacctggc agattgcgtt tttccatgta tcgcttgata gtatggagac gattgacata
      841 aacattggcc ttttgacgtg cattaatatc atctttctca atttgtgtca ggcgctcact
      901 aactgaaatt tgctcatctt caatatcttt tagttgagtt tgtaaatcct caagattttc
      961 ttcaagaact gaataagctt gggttggttc ttcttgattt gaagttacct caacaatagc
     1021 tgcctcaaaa ctctctaatt ctgtctgaat acgacgaaca tggcttgcag ctgtctcagg
     1081 aagtaaatag gtcttgttca aacgtgcaat atcttctccc aataaagtat tattctcttt
     1141 catatgttga aggtaagttg gaagagttgc aagtagattt tccactactt tctgagcagc
     1201 aatttctcga gtaaaaatat catacaaggc attgatttcc tcttgtgcct gtccattctc
     1261 atattcggca ttatccaatt ccaactgacg aatattctct tggtttttct tgaatgcttc
     1321 ataaagcaag tggaaacgcg cttcaatatc cgtttcaaca aaatgataat tagcatcaat
     1381 tagtttacga taaccggatt ccaaatcctg taattgatct ggcaattctg tagaaagcgt
     1441 cgtaaccaag gctggaacac gatccacaat atgacttaag gccaaaatgt gattttctgt
     1501 attatccaaa atcactgcgg cttccacagg gtcacccgat gaattcaagg ttacaaattg
     1561 tgaaaattca gattggatat tttctaattg tttttcaatt tcatccaagg cttgaccata
     1621 ctgttctgaa ttttcagcaa ctctatgctg aagttcctca aataaatcca aagcatgaag
     1681 aacacgacca ctatttttag attcttgctt ctctaagtct gccaaagcat tgcgaattgc
     1741 cgcaatatct tcgtcaatca aagtaatttg actctcaatt tggtcaattt gatgactggc
     1801 cttgagaaaa cgaaatgaat ggttatagcc ttctgcttca aagagattat tttcaatatc
     1861 ggcaaaagag ttgagagata aatcgaccca tttttgattc cattcacgga aagccacttg
     1921 actttgtcca atcaagtgca tattttttac agcttctact tcatcattta ctggaagatt
     1981 gtatagttct tcttttcttt cttctagcgc ctctaatctc ccctcgtttc gcttacgtag
     2041 aaagattgcc actacataag ccagaactaa aatgactgca attgcaacca ttaaataaat
     2101 tagttgtcca ttagacatat caaactcctt ttttacttga aacaatcgta acgattatat
     2161 catatttttt agaccaaggg aactacttct ccctattttt tagacatcaa gtgtactata
     2221 gacagcattt tcttcgataa actcacgacg aggctctact cgatccccca tcaacatatc
     2281 aaagatttta tctgcttctg cagcatcatc tacagaaact ctagccatca agcgatgttc
     2341 gggatccatg gttgtttccc acagctgatg atcgtccatt tcacctagcc ccttataacg
     2401 ctgaatagtc ggtttggtac gaccttcact ataacgggct aaagcttctt ggagtttgat
     2461 ttcttgatct gcacccggct ggatatattc tttaatctcg cttccaacct tgacaccata
     2521 gattggtggt tgggcaatat aaacataacc agcttctagg attggtttca tataacgata
     2581 aatcaaggtt aaaagaaggg tacgaatgtg ggctccatcg acatcggcat cggtcatcaa
     2641 aacgagtttt tggtaacggg ctttcgaaac atcaaattct gcgccaaatc ctgttcccat
     2701 ggctgtgaaa agactacgaa tttcttcgtt agctagaatc ttatccatac ttgctttttc
     2761 aacgttcaaa atcttaccgc gaattggaag gatagcctga aactcacggt tacgaccaga
     2821 tttggctgat ccaccagctg agtctccttc gacgatgaag agttctgttt cagcagggtt
     2881 attagaagaa cagtctgcta gtttccctgg aaggttggaa atttccaaac cagatttttt
     2941 acgtgtgact tcacgcgcac gcttggcagc cacacgagcc ttggcagcta aaatcccttt
     3001 ttccacgata cgtttggcaa tctgtggatt ttccatgagg aaatcggaga aggcttcact
     3061 gaagaggcga ttggtaatct tgaccacttc gctatttccc aatttggtct tggtttgtcc
     3121 ttcaaactgt ggatttgggt gtttaactga gataactgca gttaatcctt cgcgaacatc
     3181 ttcccctgtt aaattatctt cattgtcttt cagtaactta ttcttacgag cataatcatt
     3241 gataacacga gtcagtgccg tacggaaacc ttgttcatgc gttccacctt catgggtatg
     3301 aatattattg gcgaaactca tgacattttc atggtaacct gttgtgtact gcatggctac
     3361 ctcaactgtg atatcatcca tctcaccgtc tgtatagatt ggtgtatcaa agattacatc
     3421 cttgttctcg ttgatatatt caacgtaact agcaatccca ccttcataat gataatgctt
     3481 ggtttgttcc aaaccttggc gcttatctgt aattgaaatt tgaagaccgc gatttagaaa
     3541 ggccaactct tgaatccgtt tatttaattt atcaaaatca aagattgttg tttcagtgaa
     3601 aatttctggg tccggtgtga agtgaaccgt tgttccagtt ctatctgtat ccccaaccac
     3661 ctcaaggtct gcaacaacat gaccacgacg gtattcttgg taatgaatct taccgttttt
     3721 atggacatga acgtctaatt gagtggaaag ggcattaact actgacgacc ccaccccgtg
     3781 aagaccacct gaaaccttgt atccaccacc gccgaacttt cctccagcat gaaggactgt
     3841 aaagacggtc tcaacagcag gacggcctgt tttttcctga atatcgactg ggataccacg
     3901 cccatcatcc acaacagtaa tcgaatcatc tggctcaata aaaacttgaa tatggctggc
     3961 aaatcctgcc aaggcctcgt caattgagtt atcaacaatt tcccagacta gatggtgaag
     4021 accttctttt gaggttgatc caatgtacat ccctggacgc atacgaacag cctctaagcc
     4081 ctctaaaact tgaatttgac tggcatcata atcctgtgcc tgcagatttt tgatttcttc
     4141 tgtcatctta ttcctttttc ttatatgtct aatacttgtc ttaaattcac gatactggta
     4201 aacaagtggg tatcaagtcc tgcagcttga cctgcttcga tatcaatcgg ccgatcacca
     4261 atgacaagac cagagctaat ctgatacttt tctcttaaat aaagcatgga ttcgggattt
     4321 ggctttctct taaagcctga gctagaagtc accacttctg taaaataagc tgctatagag
     4381 gttttttcta aaatttccaa aacctgatca tttcgatgag agaccaaaaa atgacggcca
     4441 ccttgattta aaatgtcttc caataggtca gaaactcctt caaataaaat cgggtgttca
     4501 agctctctgg cttcattttc cttgtacttt tctaaaaaat tctctaaatt gggagcgaat
     4561 gtctcaatcg caaaaggagt agaaaccttt aaagcttgat agacactgtc atggtcttgt
     4621 gtgataccat acagtgccaa tgtttcaaca aatgcagctg ttgaagtttc ataattatcc
     4681 agtaaagttc cacctaaatc ccagatgtaa tcgtgatatt tcataccctt cattatagca
     4741 tttttttatg aaaaaagcga tgatttccct gagttttcca cataaaaaac gagagaataa
     4801 ctcccgtttt actgattttt accaaagaca tctcgataga gcattcctgt tcgtaaactc
     4861 tctgcgtccc ctcctagttg ctccaccaac tcgtaggcaa aggcaagggc tgttgaagga
     4921 ccccgactgg ttgtcaactg accatctacc actactgttt ccttgacgta gtgaccatca
     4981 aggatttgct cttgaacgcc gtcataacaa gtgtatcgct tatttttcaa tatctctgct
     5041 tgattgaggg caattggtgc cgcacaaatg gctgctagtt tcttcccttc ttgctcgaag
     5101 ctttgcaatt cttgaatcaa ggtctgatta tcacgtaaat gtgcagaacc aggcatacct
     5161 ccaggaagaa caatcatatc atagtctgat aaatctccat caaagacatg atctgctctt
     5221 acttggattg catgcgaacc cgttacttgc tcttcaaaac caaccatatc acatgtgata
     5281 ttggctcgac gcaagacatc tacaactgtc aaggcttcaa tttcttcaaa gccctgagct
     5341 aacataactg ctacttttac catgattttc tccttattta atttgtttta atacaacctt
     5401 tttccgtttg aatgggactt ttccgctctt ttcttcagct aaattagtct ggtaactcat
     5461 cgataaaagc aaaccaacac caatcaaatt actgataata gctgatcccc cttgcgaaat
     5521 gaaaggcaag ggaatccccg tcaaaggaag tagtccagtc acagcaccga tattctcaaa
     5581 gatgtggaag agcaacatca taatcaaacc tgtggaaata taagtgtaga actggttatt
     5641 tgatttaaga gtaatcttca acatacggta aatcaacatg agatagaggg caataaccag
     5701 gacagagcca ataaagccaa aatcttctgc aataaccgta aaaatcatat ctgactctcg
     5761 aactgggata agcagattcg aagcattaaa tccctgacca aataagccac cactcccaat
     5821 ggcaatctgc ccttgagcct gctggtaagt cgttgtttgg gcaaactcaa agggattgag
     5881 ccaagccaaa atccgattaa tttggtaggt cggcattcca atctggtgaa gaaaagctcg
     5941 tccgtccttg ctaataaaga tagctaagaa accagcaact cctgttacag cagtcacaaa
     6001 tactgggata ataattttcc aagaaacccc tgataataaa acgattcctg agaaaatggc
     6061 tacaaaaacc aaagccgtcc ccaagtcact ttgaagtgct aaaagaacta ggactggaat
     6121 ggtaaagaga atcatccaga aaattaacaa aaagtccagc ggaaccgtgc gtctccattc
     6181 cttatgtttc tttgtaaatt ggacaatgac acgagccaac atgaggatat aggatatctt
     6241 cataaattct gacggttgaa atagggtaat tccatttatt gatacccagt ttttggcacc
     6301 cgttgatgca actaagcttg gattataaaa tacaatcggc aagatcataa gtcccaagcc
     6361 taaaatatat agaaaggggg tcaccttcca aagaaattct gtattaaaga gcatgaccac
     6421 aaaaccaatc acaagcccca aggcaatcca ggcgacctgc tgccctaaaa tgggcagaat
     6481 attattggga taatcatgac taacggctat atagatagcc accacaccga tgaccagtag
     6541 aaaaaatact ggcaagagca aactataatc gactctagag tcgagagaac gtttcatatg
     6601 tactaacctt atactttcat acaatactat ttatcaaagt tcattaaaaa atctatcaat
     6661 agcctcgtca acttcggatc gagagatggt tttaacagtc gcttcttctg ctagagatgc
     6721 tactatttgt ttgccgtatc gttttccgac gattctccta tccaaaataa gagttaagga
     6781 acgttggtat tcacgtctca tacttcttcc caaagcctgt tttaaacgaa taatggccat
     6841 tggcaattga taatcataaa aggcattttt cccttcttga ttcagttctt gattaatctt
     6901 tttcgtcaag ggttcttgag gattttggaa aggaagcctc ggtacaactt gaatcacaga
     6961 aggatggctt gaaaaatcaa ctccctccca gaaacttgct gcaccaagca agatttgttg
     7021 ttcacctttt tcaaagcgtt tctttagctg atgaacatcc ccatttttat actgggccaa
     7081 gtggctaact gtaagtaaat ccgatactgc tagaagcatg tctttagcgg taaagagaac
     7141 caaaatcggt tgctggaaag cttgaatttc cactagtaaa gcagctacct ctctggcata
     7201 gacttctaag gaggtttctg ttaccagagg gaaatctttg accataacca cttcttgttc
     7261 ctgttttccc cgagattcaa tcttgacaaa tttggcttca ggatagccta aaaggtctgc
     7321 caaagaaacc ctctgactaa tctcaagagt agccgatact cccaagactt ggcaactctc
     7381 aggaagtaaa gaggacagaa gagtacggcc tgattttgta gaagaaatct gaattttctt
     7441 ttgactcgtt tcagttactt caagccagta atcaccttca gctgtaaaat agcgaaccag
     7501 ctcatcaaag ccttccactt ctaattctga aaaatactga tggagattgt ccagagaatc
     7561 taagatattt ttcctagatt taccagactg aaattgttct atcaagtaga gacactcaaa
     7621 gcgaatactt tctagtatcc gttgttgaac cctgttttct tctcctacta aagccttatc
     7681 aattaaatcg ataatagatt gtatatcgta ggtctcttga agcagatttt ctagagctaa
     7741 caaaatcttt tggacttcat caataatcag taaacggtca ctgacaaatt caggattatc
     7801 ttcaagtctg gtcacgagat aggcatgatt agtcactaaa agcttgcaag tctctgccct
     7861 ttcttgacta cgtttccaaa aatcttccgt cacaaataag ctctgggatg ataaattccc
     7921 atcatgacga aggtctgcta gaaaatgttg gtaacggtag agttgcccga tttcatccaa
     7981 atctcctgtc tctgtctcag taagccagac caagacttgc attttaaagc gtctaaataa
     8041 gcgattttca tcattttcct gcaaggaatg ataaaaggca tccaacttca gataattttg
     8101 tggtcccttt aagctatgaa tatctgtatg gaacacttcc ttgagacgtt taccttcttc
     8161 ttccatgatt tgattttgaa gaatctttgt cggaacacta agaacaattt gtcgctcttt
     8221 ggattgagat aaagcgggta agagatagcc ataggttttc ccaatccctg tcggcgcttg
     8281 aatcagagag aaaggttcat ctttcaatag caagccaacc tctttagcaa aactttcttg
     8341 ttcctccctc acttcaaggt tcaacagaga aatattttta gaaaagtctt gagatagttt
     8401 tcgtagctcc agagaagctg ccgttttctt aaaatacaga ccttgaactt ggaccaagtc
     8461 tggagaactc aggatagatt ggttgcgata agtttcctca ataaccaggt aagactcata
     8521 taggagagcg tcagccattt ccagcaagcg ttccaagaga cctttaggaa gctgggtcat
     8581 cttttcccgt aaaaaaagaa gtaattctgc tgtagcttgg gcatctgaaa gggctgtgtg
     8641 tgcgtgttta agaggaattc ctaattctcg acacaaaatc ggcaagctat atttttccag
     8701 ttcagggaaa aagacctggg ccaattcgac cgtatcaaca cgagggtttc ttagctcata
     8761 gccttcaaaa aataaatttt ccgccaagag attagcatca aactgaacat tatgggctac
     8821 aaaaatccca tcctccacca agtcaaagat ttttctggca acttgcgaaa aatcaggtgc
     8881 ttgcgccaga cgttggtctg tcaatcctgt cagttctttg atatgagcat ccaagggttc
     8941 atgtggattg acatccgtcg tatagtgatc gacgatttct ccatcctcaa tcacgacaat
     9001 tcccacttgg ataattttag ccttactacc tgtgctagtt gcctctaaat ccaccacaac
     9061 atagcgatta ccaatcgttt tcattataaa aaattatacc aaaaaaaggg ccatttggca
     9121 cctgcaaaca taggataatt ttcaaactca agaacactac ttttcttaga aatcccatcg
     9181 aatagagcat tctagcctgc tgattttttt aaaatagtga agaaatacga aaaattgaga
     9241 gaagaaatgt tttcatcttc cttctctcaa cgaatcatgt attttattta accatgtcag
     9301 gatcgtagtc ataaaatcct gtatcaagga aacggttttt agggtgaagt ttacgaactt
     9361 cttcatccag caagaaggct tggtcatggc taaagttgcc ctcttgaatc aagctacgcg
     9421 cttggataaa gagttttgca atctcaacaa agttctgacc aggagtgtag agcccttcta
     9481 gtttccagcg agtaaagcca tgctccacca attctgttaa tttgatcatc aaatcaaggt
     9541 cattgttggc aaagatatgg gtcccatgat tatcttcaaa aatggaatag tggctctctg
     9601 gatcacttgg ctcagccaag aagaggtcac gtttatgcgt cttttcatca tcgatatgtg
     9661 taaagttata gtagttttgc aagagtggac gtttagaatg atggatgacg ctagcaccgt
     9721 aaaccaaaac ttcagcagga atttccaaaa tctctggcat tttgaaaagt tcagctgatg
     9781 gaatttcacg cgccaaaaca gcctcagatg cgccagcctt ttgtccccag aagttaatct
     9841 gacgactgct agttaccatg gttgaagcat cgtagatggt cttaaatgaa taaccatcgc
     9901 ggttaactac gtaaaagacg cctgcatccc caatcgtaat atagtctgtc ttgatttctt
     9961 ccaagaagtc taagaaaggc ttgatacggt ccatcatatc ttggtgcatg agagcattga
    10021 ccgcaacgat caattcctta ccagcatcat gaaccaactt agcgatttca cgtaattggt
    10081 cataactaaa ggtcgttggc agacgaaggc caaaatcttt ctcaccgaca tagatacggt
    10141 ctacgccagc ttcgagtagt tgttcaactt gttcaatact ttcagcagtt gctgtaatga
    10201 caatcttttc cataagaaaa attataccac atttctccaa aatcagccat gctttgaaaa
    10261 tgaaaaggga ctttattctt tttgtaacct ttctgtaata attctctgcc gaaaaaatga
    10321 taaaataggt atgtactgtt aaggagagaa tcatgcccgt aagaaaatta caatcctatg
    10381 aggtagacta tcaagaagaa ttaaaccagc agcttcctca ttaccaagct tatacacctg
    10441 aagcgcaatc tgatgccaat ctcaaggaaa tcctattttt tattaatatc gctgtttttt
    10501 gtatctgtat tgctatcttt agttttatct ttttagcatt aaaattatca actgctcttg
    10561 cctttgccgc agcaatcgga ttcagcttac ttgttttaaa agttcaacgg tctattatca
    10621 aacgaaaacg tagaagataa atccaaaata tcgccccaat tggagcgata tttttatttt
    10681 ttctttttag atggtgtctg aatggcaatc ttcacttcaa agattgttcc cttgggttta
    10741 ttatctttga cagtaacagt tccttttaga gcatctacaa tttgcttggc tagggataat
    10801 cctaaaccaa aaccaccttt ttgccgggtt ctagctttgt ctactcgata aaaacggtca
    10861 aaaattttct ttttatcttc tgtcgaaata ccgattccat tatcagaaac aagtaaataa
    10921 agattgcgat cggtcgccga gataagaaaa tcaatttcac catcctcctc agtatacttg
    10981 acggcattat cgaaaagaat ggtcatcagt tgtttcagaa gaagctgatc tgtgacaatt
    11041 gttcgatgga tacgattttc aaaacggaag acacgattat tttccgaagc aatcatctca
    11101 tagtttgtga aagttgtatt aaaaaagcta gttggaactt ctgcaagctc cggcttaatc
    11161 ccatcatctc tccgagctaa gttcagcaag cttgtcgtta aaaaacgcat atttcggact
    11221 tcttccaaac tcgatgcaat gctttcgctc acatccataa tggtagcttc tggcttacga
    11281 aaaagggtct ctaagcgatt ttgcaaaact gcgagtggag ttcgtaactc atgactggca
    11341 ttttccacaa aagactgttg cttctgcata ctctcaagca ggggcctaac actgacccta
    11401 gctagataga gactggcaag taaagacaaa atccagaaac tagccatcac gaccacaatc
    11461 aattgctcat gcttttgact agcctgctcc aactgactgg tattaatcaa gacagcagca
    11521 tacttgatat tggttgaaac cgaactaata ttggtctcca tcaaaatcac acgatagatt
    11581 tcttcctgcc catagctatt aaaaacctga atctggtaga tatgtcctag ttctttcttt
    11641 tctaacttaa tcttatccaa gcccaaaaat cgatttccag aaagaagttg agtaaagtct
    11701 ttatcaaaga gaatgacttc cgtattggaa ctgacattag gttttatttc tactttacta
    11761 gcgtccgccc tagcattttc taaatcttta atctcttctg ttgccctatt tatagccagc
    11821 tgaataactg cttgaggatt ttcactcagt ccatgaagct tatcgtccac cgaagtataa
    11881 agactcgaat gcatgacttg taaaataatc agagtcattg tagaaaaaat cagggtgaag
    11941 acaccgaagt tgcggataaa ataactaaag tcatccgcat accatgtttt tttaagttta
    12001 ctgaacatct tttaaaagat acccaacact acgcaaggtt tgcaaattct ctgcaaaagt
    12061 ggttcccttt aatttcttac ggacttttga aacatagact tcgacaaccg aaatcgttgt
    12121 atcactatca aatccccata gacggtcaaa aatctgcgtc ttaggcaaaa tcacattttg
    12181 attttgaagg aaataaacta gtaaatcgaa ctctttcccc agcaattcga caggagtatc
    12241 ttcaacttta acggtattgg ttgataaatt aaccacgata ttcccataag tcaaggtgtt
    12301 ttcattaaac ttccctgaac gtttgagaag ggcctgaatt cgcattttaa gttcttctag
    12361 gtagaaaggt ttggtcagat aatcatccgc tcccagttca aatccatgtc ccttgtcatc
    12421 caaactttcc ttggcagtca taatcagaac tggtgtcgta attccctttt cacgcaattc
    12481 ttttaagact tggaaaccat ttttttctgg caacatcaaa tccagcaaaa tcaagtcata
    12541 gacaccactc tcagcttcgt agagaccttc ttctccatca aatacctgca taacatccgc
    12601 aaaatcgtct aaaaagtcaa atactgaatt tgacagacct aggtcatcct caaccaataa
    12661 gatttttatc atgagaaact cctccttatt aaaactatta taccaaattt gccttaaaaa
    12721 aaactcaact ctctgcattt tacatgagat agctgagttt t
//
LOCUS       DAVLAQ010000050        12759 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000050 DAVLAQ010000000
VERSION     DAVLAQ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.050"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..346
                     /locus_tag="VXB71_001575"
                     /pseudo
     CDS             1..346
                     /locus_tag="VXB71_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
     gene            368..1159
                     /locus_tag="VXB71_001576"
     CDS             368..1159
                     /locus_tag="VXB71_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451666.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            1152..1793
                     /locus_tag="VXB71_001577"
     CDS             1152..1793
                     /locus_tag="VXB71_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451667.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            1797..2429
                     /locus_tag="VXB71_001578"
     CDS             1797..2429
                     /locus_tag="VXB71_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0451668.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            2457..2744
                     /locus_tag="VXB71_001579"
     CDS             2457..2744
                     /locus_tag="VXB71_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451669.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            2890..5403
                     /gene="secA"
                     /locus_tag="VXB71_001580"
     CDS             2890..5403
                     /gene="secA"
                     /locus_tag="VXB71_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0451670.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            5484..6515
                     /locus_tag="VXB71_001581"
     CDS             5484..6515
                     /locus_tag="VXB71_001581"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0451671.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            6517..7548
                     /locus_tag="VXB71_001582"
     CDS             6517..7548
                     /locus_tag="VXB71_001582"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0451672.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            7587..7955
                     /locus_tag="VXB71_001583"
     CDS             7587..7955
                     /locus_tag="VXB71_001583"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0451673.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            7945..9048
                     /locus_tag="VXB71_001584"
     CDS             7945..9048
                     /locus_tag="VXB71_001584"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0451674.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            9067..11082
                     /gene="recG"
                     /locus_tag="VXB71_001585"
     CDS             9067..11082
                     /gene="recG"
                     /locus_tag="VXB71_001585"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0451675.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            11399..12379
                     /locus_tag="VXB71_001586"
     CDS             11399..12379
                     /locus_tag="VXB71_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0451676.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         3703 a         2390 c         2903 g         3763 t
ORIGIN      
        1 aagtgctgtt ggaactactt tcgtagaagc aaatcagata ggtgctttta gtaattttgt
       61 tattactacc agttataaga gaacaggtta tttgactaaa gaaaatgaag gtgcggaata
      121 tatcatgaac ttaaatcctt gtagaaattt acatcccatg actgttaagc atcgtatagt
      181 aaattctaat ggagaagctc gtagtggata atcgttaaca acctgtggta ctcgttcaac
      241 tcatggtaat tgggcaacgg ttggctatgt ttatgcagca gatatggcaa gacaaaattg
      301 gtgggattta tcagctgcca tttcaggtag ttggtcacca aattaattcg taaagtaggt
      361 ataatttatg aagattcctc tcttaacttt ggcaaggcat aaatttgttt atgtcttgct
      421 tactttgctt tttcttgctt tggtttatcg tgacgttttg atgacttatt tcttttttga
      481 tattcatgcg cccgatctag ctaaattcga tggacaagca attaaaaatg acttattaaa
      541 atcagcatta gattttcgta ttctccagtt caatctaggt ttttatcaat catttattat
      601 tccaatcatc attgttttgc taggttttca atatattgag ctgaaaaata aagttttacg
      661 attgagtatt ggaagagaag tgagctatcc agggttaaaa agaaagttga ctttgcaagt
      721 tgcaagtatc ccttgtttga tatatttagt gactgtgctg acaattgcaa ttataaccta
      781 tttccttggg actttttctc ctcttggatg gaattctcta ttttctgatg gaagtggttt
      841 acaaagactc ctagatggag agataaaaag ctatttgttc tttacttgtg tcctgctaat
      901 cggtattttc atcaatgcaa tctatttttt acaaatagtt gattatgtgg ggaatgtgac
      961 tcgttcggca atcacctatt tgatgtttct ttggcttggt tctatgctgc tctatagtgc
     1021 cttgccttac tatatggttc ctatgacgag tttgatgcaa gctagctatg gggatgtaag
     1081 tttgatgaaa ctctttactc cttatatcct ttatattgtc ccttacatgg tgcttgaaaa
     1141 atatgaagat aatgtttaag aattttaaca atattttgct aaagagaaag attgttttac
     1201 tacttcgtat agttctgatg atgattttga taaaccatct attgtcaaca gcggttcaaa
     1261 agcaggatgc tgttatcttt ttcaagagag aattgatttc aattttttcc tataatgact
     1321 attctgaagc gaatttagaa atccccaaac tcttgttaaa cctttcgctt ttcatggtag
     1381 gatggctctc tgtcatttta cttgaaagtg atttggcaga ccattaccat cacttgattc
     1441 gctatcaatc aagctccttt ttcgattata caaggaaacg attggttgtc atttctaaat
     1501 tttttactca agatttgttt gtctggttcc ttggtttact tccgctagga attcatttca
     1561 aaacagtcgc acttttcttt ttacttgctc agttaatgat gttgtactta ctactgtctt
     1621 atctgatagc actgattagt gcgggcgctg gtttttcctt ttttctctat tttttagtat
     1681 ttgtgggaca agaatggatg atggatcata ttgtaacagt gtatttacta ctcttaagtt
     1741 tattagttat gttgattgtt agtcgcttgg aagagaaatt taagaaagga taaacgatga
     1801 gacttgaaat tataaatgga cagaaaattt atgggaaaag acctatttta aatcagttga
     1861 atttggtgtt tcaatcagga aaaatttatg gacttaaagg tgataatgga tctggcaaga
     1921 cggttctttt aaaggtactt gctggctata ttaagcttga caaaggaaaa gttcttcaag
     1981 acgggaaagt ctacgggata aaaaatcatt atattcagga tgcaggaatt ttaattgaaa
     2041 aagtcgagtt tttatctcat ttatccctga gagaaaattt ggaactgtta aggtattttt
     2101 catctaaagt tacggaaaaa agaattgcct attggattca atactatgat ttacaggaat
     2161 ttgaagacgt tgaataccgt catttatcct tgggaacaaa gcaaaaaatg gccttgattc
     2221 aagcctttat ttcctctcct tctatactct ttctcgatga acctatgaat gctttggatg
     2281 agaagagtgt gaggttaacc aaacaggtca ttttatctta cctgaaaaaa gaaaatggtc
     2341 tggttatcct gacgtcgcac atatcggaag atatttcaga cctttgtaca gatgtattag
     2401 ttgtcgaaaa tggacatata caaatgtaaa ggatatacaa tcctaggaga tggcttatgg
     2461 cacatctaaa atcatttatt acacgctatt ccaaggttta tattggttta gttctgctga
     2521 tctggctgtc tttcttcttt atcccttggg atagagcgat tctgggggta aggattgaca
     2581 tcttcatcat acagaaaatc ttgctagctt ttggaattct gtccattctc atggccttgc
     2641 tgtccaagaa agtcagtctc tttgtttttg gactgatttg ctgtctttct ctttggatta
     2701 acttatttat cacatttgcc attttgccga tttttggcaa ttaaacagtc ataaaagtcg
     2761 gagaggttag cttgaaaact aacctctttt tccttttcaa aatggggatt cttccttgaa
     2821 aataatcagt aattgtgcta aaattaaagg aacattctaa aatattcgga atttaaagta
     2881 aggaaaaaca tggctaatat tttaaaaaca attatcgaaa atgataaagg agaaatccgt
     2941 cgtctggaaa agatggctga caaggttttc aaatacgaag accaaatggc tgctttgact
     3001 gacgaccaac taaaagcaaa aacagttgaa tttaaggaac gttatcaaaa tggagaatca
     3061 ctggattcat tgctttacga agcatttgcg gttgtccgtg aaggtgccaa acgtgtccta
     3121 ggtctcttcc cttataaggt tcaggtcatg ggggggattg ttcttcacca tggtgacgtg
     3181 ccagagatgc gtacagggga agggaaaacc ttaactgcga ccatgccggt atacctcaat
     3241 gccctttcag gtaaaggggt tcacgtagtt acggttaatg aatacctgtc agaacgtgac
     3301 gcgactgaga tgggtgaatt gtactcttgg cttggtttgt cagtagggat taacttggct
     3361 accaaatctc caatggagaa aaaagaagcc tatgagtgtg atattactta ctcaactaac
     3421 tcagaaatcg gatttgacta ccttcgtgac aacatggtcg ttcgcgctga aaacatggta
     3481 caacgtccgc ttaactatgc cttggtcgat gaggttgact ctatcttgat tgacgaggct
     3541 cgtacacctt tgattgtatc aggtgccaat gcggttgaaa ccagtcagtt gtatcacatg
     3601 gcagaccact atgtaaaatc tttgaacaaa gatgactaca tcatcgatgt gcagtctaag
     3661 actattggtt tgtctgattc agggattgac agggctgaaa gctacttcaa acttgaaaac
     3721 ctctatgaca tcgaaaacgt ggctttgacc cactttatcg ataacgccct tcgtgccaac
     3781 tacatcatgc ttctcgatat tgactatgtg gtgagcgaag agcaagaaat cttgattgtc
     3841 gaccaattta caggtcgtac catggaaggt cgtcgttatt ctgatggatt gcaccaagct
     3901 attgaagcca aagaaggtgt gccaatccag gatgaaacca agacatctgc ctcaatcacg
     3961 taccaaaacc ttttccgtat gtacaaaaaa ttgtctggta tgacgggtac aggtaagact
     4021 gaggaagaag aatttcgtga aatctacaac attcgtgtta ttccaatccc aacaaaccgt
     4081 cctgttcaac gtattgacca ctcagacctt ctttatgcaa gtatcgaatc taagtttaaa
     4141 gcggttgtcg aagacgttaa ggctcgttac caaaagggtc aacctgtctt ggttggtaca
     4201 gtagcggttg aaactagtga ctacatttct aagaaattgg ttgcagctgg tgttcctcac
     4261 gaagtcttga atgccaaaaa ccactataga gaagcccaaa tcatcatgaa tgctggtcaa
     4321 cgtggtgccg ttaccatcgc aaccaacatg gcgggtcgtg gtaccgacat caagcttggt
     4381 gaaggtgttc gtgaacttgg aggactttgt gttattggta cagaacgtca tgaaagtcgt
     4441 cgtatcgata accagcttcg tggacgttca ggtcgtcaag gagatccagg tgagtcacaa
     4501 ttctacctat ctcttgaaga tgatttgatg aaacgttttg gttctgaacg cttgaaggga
     4561 atctttgaac gtctcaacat gtctgaagag gccattgagt ctcgcatgtt gacgcgtcag
     4621 gttgaagcag ctcagaaacg tgtcgaagga aataactacg atacccgtaa acaagtcctt
     4681 caatacgatg atgtcatgcg tgaacaacgt gagattatct atgctcaacg ttacgatgtc
     4741 atcactgcag atcgtgactt ggcacctgaa attcagtcta tgatcaaacg cacgattgaa
     4801 cgtgtcgttg atggtcatgc gcgtgccaaa caagatgaaa aactagaggc aattttgaac
     4861 tttgctaagt acaacttgct tcctgaagat tctattacga tggaagactt gtcaggcttg
     4921 tctgataagg ccatcaagga agagcttttc caacgttcct tgaaggttta cgatagtcag
     4981 gtttcaaaac tacgcgatga agaagcagtt aaagaattcc aaaaagtttt gattctacga
     5041 gtggtggata acaagtggac agatcatatc gatgcccttg atcaattgcg taacgcggtt
     5101 ggacttcgtg gctatgctca gaacaaccct gttgttgagt atcaggcaga aggtttccgt
     5161 atgtttaatg atatgattgg ttcgattgag tttgatgtga cacgcttgat gatgaaagca
     5221 caaattcatg aacaagaaag accacaggca gaacgtcata tcagtacaac agcgactcgc
     5281 aatatcgctg ctcaccaagc aagtatgcca gaagatttgg atttgagcca gattggacgc
     5341 aatgaacttt gcccatgtgg ttctggtaag aaatttaaaa actgtcacgg taaaagacaa
     5401 taaaatgaga tagtttagag gcggatatct tgtgaaaagt aaatttttac tgggtatccg
     5461 tttgctttat aaggagatga gttatggtat ttacagcaaa aagctctaaa ataaatatag
     5521 aagaagttcg tgccttgtca aaattagaag gtcaggcttt ggagaggaaa tcacagcgag
     5581 atcaagagct agaagccatt atacgtggag aagaccagcg aattctcttg gtaatcgggc
     5641 catgctcatc tgacaacgaa gaagctgtcc ttgaatacgc taagcgtttg gcagtcctac
     5701 aagaagaagt ggcagatcgt atctttatgg ttatgcgtgt ttatactgcc aaaccccgta
     5761 ccaacggaga tggctataag ggcttgattc accagcctaa cgcgacagaa gcgcctagtc
     5821 ttatcaatgg aatcaaagcc gttcgccatc ttcactatcg tgtcatcaca gaaacaggga
     5881 tgacaactgc tgatgaaatg ctttatcctg aaaaccttcc gcttgtagat gatttgattt
     5941 cttacatggc agttggtgcc cgttcagttg aagaccagca acaccgcttt gtggcaagtg
     6001 gggcaggatt ttctactggt tttaaaaatc caacctctgg aaatctcaat gtcatgttta
     6061 atgggattta tgctgctcaa aacaaacaaa gtttcctttt cttaggaaaa gaagtagaaa
     6121 caactgggaa cccgctttca cacgctattc ttcgtggtgc tcttaatgag tatggaaaaa
     6181 atattcccaa ctactattat gacaatttaa ttgataccat tgcccagtat gagaaaatgg
     6241 gcttggaaaa tccttttatc atcattgata ccaatcatga caattctggt aagcagtata
     6301 ttgaacagat ccgaattgtc cgccagacct tgattaaccg tgcttggaat gaaaaaatta
     6361 agcagttcgt tcgtggtttt atgattgagt cttatctgga agatggtcga caaaatgagc
     6421 cagaagtatt tggtaagtct atcacagacc cttgcctggg ttgggataac acagaagctc
     6481 ttgtcagaga aatttacaaa acgttaggag aataagatgg catttattga aaaaggtcaa
     6541 gaaatcgata tggaagtcat caaggctgaa acccaattgt ctgcggaagc cttgagactc
     6601 aaggaaagcc gtgacaggga attggcagat attatttcag gggaagatga ccgtattctc
     6661 ttggtgattg gtccttgctc ttctgataat gaagaggcgg tcttggaata tgctcgccgt
     6721 ttatctgcct tgcaaaagaa ggtagcggat aagattttca tggtcatgcg cgtgtatact
     6781 gctaagcctc gtaccaatgg agacggctat aaaggattag ttcaccagcc agatacttct
     6841 aaggctccaa gcctgattaa tggcttgcag gctgtgcgcc agttgcacta ccgcgtgatt
     6901 acagagactg gtttgacaac ggcagatgag atgctttatc cgtcaaatct gatcttggtg
     6961 gatgacttgg tcagctacca tgccgttgga gctcgttctg tggaagacca agagcaccgc
     7021 tttgtggctt ctgggattga tgcaccagta gggatgaaaa atccaacctc aggaaatttg
     7081 ggtgttatgt ttaacgccat ctatgctgct caaaacaagc aaaccttcct ttatcatggg
     7141 caggaagttg agacatcagg taatcctttg gcccatgtta tcctccgtgg agcagtcaac
     7201 gagtatggca attatatgcc gaattactac tatgaaaatc tactccaagc cattgaacgc
     7261 tatgaaacca tgggacttga aaatcctttt atcctcattg acaccaacca tgataactca
     7321 ggcaagcaat atatggagca gattcgaatt gttcgccaga ccttgcagaa tcgtgattgg
     7381 aatgagaaaa ttaaaaagac ggttcgagga tttatgattg aatcttacct agcagatggt
     7441 cgtcaaaacc aaccagagat ctttggttgc tctattactg acccttgcct aggttgggaa
     7501 aatacagagg ccttggtaga agagatttat gttaccttga caaaataagt gaaaaggatg
     7561 gagttgggga atctcaactc cttttgatga gaatgatagt tggacacgga attgacatcg
     7621 aagaattggc ttcgatagaa agcgcagtta cacgacatga aggatttgct aagcgtgtac
     7681 tgaccgctca ggaaatggag cgcttcacca gtctcaaagg acgcaggcaa atagaatatt
     7741 tagctggtcg ctggtcggct aaggaggcct tttccaaggc tatgggaacg ggcattagca
     7801 agctcggttt tcaggatttg gaagtcttga acaatgaacg tggggcgcct tattttagtc
     7861 aggcaccatt ttcaggaaag atttggctgt ctatcagcca caccgatcag tttgtgacag
     7921 ccagtgtcat tttggaggaa aatcatgaaa gctagtccac atagaccaac caaggctctg
     7981 attcatctgg gagctattcg acaaaatatt cagcaaatgg gggctcatat ccctcaagga
     8041 acgctcaagt tggctgtggt taaggccaat gcttatggtc atggagctgt tgccgttgcc
     8101 aaggcaattc aagatgatgt tgatggcttt tgcgtttcca atatcgatga agccattgaa
     8161 ctcagacaag ctggactcag caagccaatc ctcattttag gagtttctga aatcgaagct
     8221 gttgctctag ctaaagaata tgacttcacc ttgacagtgg ctggactgga gtggattcaa
     8281 gcactcttag ataaggaagt ggacctaact ggattgacag tccacctcaa gattgattca
     8341 gggatgggac ggattggttt tagagaggca agtgaggttg agcaggctca agatttgctc
     8401 caacaacacg gtgtttgtgt tgaaggaatc tttacccact ttgctactgc tgatgaggaa
     8461 tcagatgact attttaatgc ccagttagaa cggtttaaaa ctattttagc tagtatgaag
     8521 gaagttccag agctggttca tgctagcaat tctgcaacga ctctttggca tgtagagact
     8581 attttcaatg cggttcgtat gggagatgcc atgtatggcc tcaatccaag tggagcggtc
     8641 ttggatttgc cttatgattt gataccggcc ttgaccttgg agtctgctct ggttcatgtc
     8701 aagacagttc cagctggagc ttgcatgggc tatggagcaa cttatcaagc ggatagcgag
     8761 caagtcatcg cgaccgtgcc aatcgggtat gcagatggat ggacaagaga catgcaaaat
     8821 ttctctgtct tggtagatgg ccaagcttgc ccaattgtcg gcagggtttc gatggaccaa
     8881 atcactattc gattgcctaa gctttatccg ctaggaacca aggtaacctt gattggctcc
     8941 aatggggata aggaaatcac tgcaactcag gtagcgacct accgcgtaac cattaactat
     9001 gaggtggttt gcctcctcag cgaccgtatt ccgagagaat attattagaa aagaaaggag
     9061 tggagcatga atctacatca acccttgcat gtcttgcctg gtgtgggacc aaagtcagca
     9121 gaaaaatacg ccaaactagg aattgaaaac ttgcaagatc tcttgctcta ctttcctttc
     9181 cgttatgaag acttcaaaac caagcaggtg ctggagctgg aagacggtga gaaggcagtt
     9241 ctttctggtc aggtagtgac tcctgctagt gtccagtatt atggtttcaa gcgcaatcgc
     9301 ctgcgtttta gtctcaagca gggagaggtc gtttttgcgg tgaatttctt taaccagccc
     9361 tatctggctg ataaaataga gttgggagca acccttgctg tctttggaaa atgggaccgc
     9421 gctaaggcta gtctgactgg gatgaaggtt ctggctcagg tagaagatga cctccagcct
     9481 gtctatcgtc tggctcaggg aatcagtcag gccagtctgg tcaaggtcat caagacggct
     9541 tttgatcagg gactggacct cttgatagaa gaaaatctgc cccagtcttt actagacaaa
     9601 tacaaactca tgtcccgttg tcaggcagtc cgagctatgc attttccaaa ggatttggca
     9661 gaatacaagc aggctcttcg ccgtataaag tttgaggaac tcttttattt ccaaatgcag
     9721 ctgcagatgc tcaagtctga aaatagagtt cagggaagtg gtctggttct gaattggtct
     9781 caggaaaaag tgacagcagt taaagtaagt cttccttttg ccctgaccca agctcaggaa
     9841 aagagtttgc aggaaatttt aactgatatg aagtccgacc accacatgaa tcgtctccta
     9901 caaggggatg tggggagtgg aaaaacggta gtcgctggct tggccatgtt tgcggcagtg
     9961 acagcaggtt atcaggctgc cctaatggta ccaacagaaa tcctcgcaga gcaacacttt
    10021 gagagtttac agaacctttt tcccaatttg aaactggctc tcttgatagg ttccttgaaa
    10081 gctgcagaaa agagagaggt cttggagacc attgccaagg gtgaggctga tttgattatc
    10141 ggaactcacg ctctgataca agatggggtg gagtatgctc gtcttgcttt gattattatc
    10201 gatgagcagc accgttttgg tgtagggcaa aggcgtattt tacgggaaaa aggtgacaat
    10261 ccagatgtcc tcatgatgac ggcgactccc attccacgga cgcttgccat cacagccttt
    10321 ggagatatgg atgtttccat tatcgaccag atgccagcag gtcggaagcc tattgtgacg
    10381 cgctggatca aacatgagca actacctcag gtcttgactt ggttagaggg ggaaattcaa
    10441 aaaggttccc aagcctatgt catctctcct ttgattgaag aatcagaagc tctagatttg
    10501 aaaaatgcca ttgccttatc agaggagttg acgactcatt ttgcaggcaa ggcagaggtg
    10561 gctcttctac atggtaggat gaagagtgac gaaaaagacc agatcatgca ggatttcaag
    10621 gagagaaaga cggatattct ggtttcgacg acggttattg aggttggggt caacgttccc
    10681 aatgcgactg tcatgattat catggatgcc gatcgcttcg gtctcagtca acttcaccag
    10741 cttagaggtc gtgtcggtcg gggggacaag cagtcctacg ctgttctcgt tgctaatccc
    10801 aagacggatt ctgggaaaga ccgcatgcgt atcatgacag aaacgaccaa tggatttgtc
    10861 cttgcggagg aagatttgaa aatgcgtggt tctggtgaga tttttggaac cagacagtca
    10921 ggacttccag agttccaagt ggctgatatt atcgaagatt ttccgatttt agaagaagca
    10981 agaaaggttg ctagctacat tagttctata gaagcttggc aagaagatcc agagtggcgc
    11041 atgattgccc ttcatctgga aaagaaagaa catctggatt aagctttctc taaggaaaac
    11101 ttaagctagt ttttaggttt ggctcttata ctaaagtcat caaaaagaaa cgaggactct
    11161 catatgacag taacgattaa agtaaattac caaaccactt tccaaaagaa ggaagcaaaa
    11221 aactagtata aacagaagag agagcgaaat gctctttttt cgtttctaaa actactttca
    11281 gcccatcatc ctaaaagtaa agaatctaaa ttcactttct atttaccctt ctttcttgca
    11341 ttgattacat agatatgcta cagttgtggt aacgattaca aaataaaagg agcatgctat
    11401 gaaaaatcca gctttgctag aagaaattaa gacctataga ggaagggatg aggttccgga
    11461 agactttgat gctttctggg atggggaagt gaaaaatgtt tccacacttc catcctacca
    11521 cttggaggaa agagatttcc acattcctca agtcaagtgc tatgagttaa catttgaagg
    11581 aagcaaggaa ggaaaggtct atgcacgcat tgttcttcca aagagtgagg agaaggttcc
    11641 attaatcttc cattttcatg gttatatggg acgtggctgg gactgggccg acatgctggg
    11701 cttcaccgta gctggttacg gtgttgtttc catggatgtg cggggccagt caggttactc
    11761 acaagacggc ttgcgttctc ctttaggaaa taccgtgaag gggcatatta tccgtggtgc
    11821 tatggaaggt cgggaccacc tcttttataa ggatgtttat ctggatattt accagttggt
    11881 cgaaattgtt gctagtctgt ctcaggttga tgagaagcgt ctttctagct atggtgcctc
    11941 acaaggaggg gctctagctc tagttgcagc agcgctcaat cctcgaattc agaaaacagt
    12001 tgccatttat cccttcttgt cagacttcag acgggtgatt gagattggta atactagcga
    12061 ggcttacgac gaacttttcc gttatttcaa gtttcacgac cccttccatg aaacagagga
    12121 ggaaatcatg gcgacccttg cctatatcga tgtcaaaaat cttgcccatc gtatccaagg
    12181 tgaggttaag atgattacgg gcttggacga cgatgtttgc tatcccatta cccagtttgc
    12241 gatttataat cgtctgacct gcgataaaac ctatcgcatc atgcctgagt atgctcacga
    12301 agccatgaat gtatttgtca atgaccaagt ctacaactgg ctctgtggaa gtgagattcc
    12361 ttttaaatat ctaaaataag gagtcgactc taagcacaaa atcttaaaaa ttacaaacac
    12421 gcatagtatc aggggattaa aaaaacttga tactatgcgt tttatcatgg aaatatagta
    12481 aaatgaaaca agaataggac aaaacgatca ggacagtcaa atcgatttct aacaatgttt
    12541 tagaagcaaa tgtgtactat tctagtttca atctattata tttatagaat tttttgttgc
    12601 tagatttgtc aaattgctta aaataatttt tttcagaaag caaaagccga tacctatcga
    12661 gtagggtagt tcttgctatc gtcaggcttg tctgtaggtg ttaatacttt tcaaaaatct
    12721 ctttaaacca cgtcagcttc gccttgccgt atatatgtt
//
LOCUS       DAVLAQ010000051        12686 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000051 DAVLAQ010000000
VERSION     DAVLAQ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.051"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..240)
                     /locus_tag="VXB71_001587"
     CDS             complement(<1..240)
                     /locus_tag="VXB71_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0451677.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIA"
     gene            483..776
                     /locus_tag="VXB71_001588"
                     /pseudo
     CDS             483..776
                     /locus_tag="VXB71_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            883..1234
                     /locus_tag="VXB71_001589"
                     /pseudo
     CDS             883..1234
                     /locus_tag="VXB71_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1510..2816
                     /locus_tag="VXB71_001590"
                     /pseudo
     CDS             1510..2816
                     /locus_tag="VXB71_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2856..3866)
                     /gene="tsaD"
                     /locus_tag="VXB71_001591"
     CDS             complement(2856..3866)
                     /gene="tsaD"
                     /locus_tag="VXB71_001591"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0451678.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3856..4293)
                     /gene="rimI"
                     /locus_tag="VXB71_001592"
     CDS             complement(3856..4293)
                     /gene="rimI"
                     /locus_tag="VXB71_001592"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0451679.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENIFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(4290..4973)
                     /gene="tsaB"
                     /locus_tag="VXB71_001593"
     CDS             complement(4290..4973)
                     /gene="tsaB"
                     /locus_tag="VXB71_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0451680.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            5151..5336
                     /gene="cibA"
                     /locus_tag="VXB71_001594"
     CDS             5151..5336
                     /gene="cibA"
                     /locus_tag="VXB71_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0451681.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            5338..5490
                     /gene="cibB"
                     /locus_tag="VXB71_001595"
     CDS             5338..5490
                     /gene="cibB"
                     /locus_tag="VXB71_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0451682.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(5813..6028)
                     /locus_tag="VXB71_001596"
     CDS             complement(5813..6028)
                     /locus_tag="VXB71_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451683.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            6308..6541
                     /locus_tag="VXB71_001597"
     CDS             6308..6541
                     /locus_tag="VXB71_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0451684.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6543..8222
                     /locus_tag="VXB71_001598"
     CDS             6543..8222
                     /locus_tag="VXB71_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0451685.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            8276..8368
                     /locus_tag="VXB71_001599"
                     /pseudo
     CDS             8276..8368
                     /locus_tag="VXB71_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8575..10488)
                     /gene="mnmG"
                     /locus_tag="VXB71_001600"
     CDS             complement(8575..10488)
                     /gene="mnmG"
                     /locus_tag="VXB71_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0451686.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(10498..10953)
                     /locus_tag="VXB71_001601"
     CDS             complement(10498..10953)
                     /locus_tag="VXB71_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0451687.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQYGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(11094..12215)
                     /gene="mnmA"
                     /locus_tag="VXB71_001602"
     CDS             complement(11094..12215)
                     /gene="mnmA"
                     /locus_tag="VXB71_001602"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0451688.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
BASE COUNT         3619 a         2950 c         2523 g         3594 t
ORIGIN      
        1 ggcaatatct aaatttttat aatcatcaat aacctttgaa tctctagata cgattatcaa
       61 aataggatat agagacatcc ttctgatctg ctttttacaa agtccaatta tatgcggatc
      121 tatacctcca caatgtccat tattatacct aactataata tgagccgaaa acactatatc
      181 cttaatgtct ccatatccat cagggatatt aatatttatt tttccacaac tatattgcat
      241 tgtaaccatc tccttaaacg acgcattatg atatttgata gagaaatttt tatgaataac
      301 tcaataattt tatagtaaat catgcttata tctcaaagat acctattttc tcttgtctcg
      361 accttctcca aagaattgct ataatactat tacaaataca tctgcactac acttcaaatt
      421 ttagcactgt ataaaaacgt ttcaacacac taactttaag aaaacttcca ctattaattg
      481 aaaaagttga tagagataaa ttaaagatct atattgaaac tcatcccgat gcttatttga
      541 ctgaaatagc tgctgaattc aactgtcctc caacaactat tcattacgct ctaaaggcta
      601 tgggatatag tctaaaaaag agctgtacct actgcgaaca agacccagaa aaagtaaatc
      661 ggttccttaa agaattgaat cacttaagct acctgactcc tatttatatt tatgagacag
      721 gggttgagac ctatttttat ctcgaatatg atcgagcctt gagcaggcag ttagtctctc
      781 tggaagaaga tataattatt tgaattaaga tcgagacaac gcacaccaga gattgcgata
      841 ctgttataga agtactaatg cccttttttg tttcaatata ctatggctcc gatgacctat
      901 aaagatacga tgacgagtga ctttttcgaa gcttgcttcc aaaaattctt actacctact
      961 ttagatacac catcccttat cattatggac aatgcaaggt ttcacagaat gaacatgtgt
     1021 aaggagcagg gcatagactg ttaccacttc ctacctattc acccgagtat aatcccattg
     1081 agaaaatatg ggcttacatc aaaaacatct cagaataata ttgtcaaatt acgatgcttt
     1141 tcttgaggca cttttgtcct attcttgttt cagccgacta tactccgtta ttgggcagct
     1201 acggaacagt cgatgggacg atggggggac ataaaaaaat cctccagttt tgttttttat
     1261 aacagtatac tggagaattg acaatctcgg tagatacctc gttatagcgc ggttacttat
     1321 taggcagtta caaaacaact gtgaacagaa aacattccag agtcagacaa gactttggaa
     1381 tgttttggct ctataatttc tgtagtgggt aatcccaccc caggaattat agggtcgttt
     1441 cttgtagaaa aaaagcccca tatgacctat aatgaaaagc gtctaaccaa ctcattagaa
     1501 agggttcata tggaacaact taagaatacc acagatttgc tcggattgaa agacaaaaat
     1561 atcaaaatct tgtctgttct gaaataccaa acccatctag tcgttcaggc aaagttggat
     1621 tcccccgctc ctccttgtcc tcattgtcaa gggaagatga tcaaatacga cttccagaaa
     1681 gcctctaaaa ttccgcttct cgactgtcag ggtttaccca cggtactaca tctcaaaaag
     1741 cgccgctttc agtgcaagaa ttgccttaag gtggtcgttt ctcaaacatc cattgtcaag
     1801 aaaaattgcc agatttccaa catggtgaga caaaaaatcg ctcagctcct ccttgaaaag
     1861 cagtctatga ctgagattgc ccacagattg gcggtctcaa cttccaccgt catccgaaaa
     1921 ctgagggaat ttaagtttga aaccgattgg accaagttgc caaaagttat gagttgggat
     1981 gagtatagct tcaaaaagag caaaatgagc ttcattgccc aagattttga gtccaaatcc
     2041 atcctcgcaa ttttagacgg gcgaactcat gcggtgattc gaaaccattt ccaacgctat
     2101 cagagagagg ttcgggagct ggtcgaggtc atcaccatgg acatgtacag cccttattat
     2161 cggctcgcta agcaactctt tccaaaggcg aagattgttc ttgaccgctt ccacattgtc
     2221 caacatctga gccgagctat gaaccgagta cgaatccaaa tcatgaacca atttgaccga
     2281 aaatccttgg agtatcgggc gctcaagcgc ttttggaacc ctcgcttttt cgtttctagg
     2341 ctcgggctaa atcagtccac tggactgatt tactacacca ggatagcttc aagctctgtc
     2401 agaaacgatt ctatcagccc acgtttcgaa tgcacttaac ccatcgggaa gtacgagata
     2461 agctgctttc ttactctgag ggattacagg ttcactacga actctatcaa ctcctgctct
     2521 ttcattttca agagaagaat gccgaccatt tctttggatt gattgagcaa gaactgccaa
     2581 cggttcatcc gctttttcaa acggtctttt ggactttttt aagggataga gataagatta
     2641 tcaacgcact taagctgcct tattccaacg ctaaacttga agcgaccaat aatttgatta
     2701 aggttatcaa gcgcaaagcc tttggtttcc ggaactttaa caattttaaa aaacggattt
     2761 tgatgacttt gaacatcaaa aaagagagta cgaatttcgt actctccaga ttgtagcttt
     2821 tcgcctaccc actacacttg acaaagagcc actctttatt ccatggtatc aaaggcaaga
     2881 cttggtttgg cattgaggtc ccagcctgcg aagttttctt tgttccactc gctgacgctg
     2941 gcataggcaa tcatacctgc attgtctccg cagagtcgca gaggggggat gataaccttg
     3001 acatctgtga tttcggctgc taggcgttct ctgagacctt tattggctgc cacaccacct
     3061 gccacaacta gggttttaac aggatatttc tccaaagcct tcttggtttt tgccatgaga
     3121 atgtccataa ctgctgcttg gaaggaagca cacaaatctt ctgtagacag gctttctccc
     3181 ttttgctcgg cattgtgatg aagattgata aaggcagatt tcaaacctga gaaggagaac
     3241 tccagattat cttccttaat catggcacgg gggaaatcat aaatatcctg cccctgatga
     3301 gccagctcgt caatctcacg acctgcagga taggtcaagc ccatgacacg accgaccttg
     3361 tcataagcct ccccaactgc atcgtctcgt gtctccccaa caatcttgta atctcctgcc
     3421 tccgaaacat agaccaactc tgtgtgccca ccgctaacca agagggctag caagggaaac
     3481 tccaaaggct ccacactctg agctgccatg aggtgcccag ccatgtgatt aacaggaatc
     3541 agtggaagtc cgtgagccca agcaaaggcc ttggcagctg acaaaccaac tagcaaggct
     3601 ccgaccaagc ctggtccgta ggtaaccgca acagctgtca cgtcctcttc ggtaatccct
     3661 gcttctgcca atgcctcctc gatacaggct gtaatgacct cgacatggtg acgactggct
     3721 acttcgggca ctacgccacc aaaacgtttg tgactctcaa tttgactagc aatgacattg
     3781 gacaagagct catcgtcgtt tttcaagacg gcgacactgg tctcatcaca ggatgtctca
     3841 aatgctaaaa tatatctatc cttcatctat ttctctcttc atgataatgg cgtcctcgac
     3901 tgggtcatgg tagtaggcct ttcgctcagc gatgaccgcc attttttctt tcttgtaaaa
     3961 tgcttgcgct cgttgatttg actttctgac ttcgaggaaa atctccttat ctgtcggcaa
     4021 ttgagcaaac aaggctgacg caattccctg accctgataa gctcctttaa cagcgatttg
     4081 caagacttct gcctcaaaga tattttcctg aacagctaga aaaccaatca cttctgcccc
     4141 atcataagcc agaacatacc aagtctggtc ttgggacagg tctgcttgga tttgctccag
     4201 agtccaagga ctgactaggt aaacagctgc cataacagcg tagatggctt gagctaggtc
     4261 aggctgttgt tgaattcgct tgatttctat cataggcgtt taatgtagga ctcaccagac
     4321 tcggtatggt tcttgagcca gttttcctca gcctcgactc gtttgaggta attcggcaca
     4381 aaatcatgca aggagtctgc ttccttgtcc caagctaaaa gagcaagatt ggctgcattg
     4441 ggcaatgttt ctttgtaatc agtccttggc aagtgttttt gaatctgctc aacaaagggg
     4501 ccaacttctc cgacaaaggt tacctgacta gtacccttga ctttttctag cacctcttca
     4561 aaagataggt gcgcttctgc catgacaggt ttggcatttt cataaaatcc tgcataaaca
     4621 ttattgcgac gcgcatccat caaggggaca aacaaacctt cttgttggtg gggcaccaga
     4681 gccaagagac tcgacatacc aaccaactcg atgttcaggg tgtaagctaa ggtcttagca
     4741 gttgctaccg caattcgcaa gcctgtatag ctacccggcc cttcagctac cacgattcgg
     4801 tccaaatcct tgggtgtcca atccaaactt gccatcaaaa aatcgatggc aggcataaga
     4861 gtaatactgt gatttttctt aatattaatc gtcgtctcgg caagaacctg cttatcctct
     4921 aaaatagcca gagaaagagc cttgctggac gtatcaaaag ctaatacttt cataacacat
     4981 tcctatcttt ttgtctgctt actattatac tacaaaagct ggcacatggg aattttcttt
     5041 gcccccagac aagagtgccc tcacttaact aaaaataatt taaaaaaatg ctcacttttc
     5101 cttttctttt ccgaatataa aagtgaacaa gaaaaaagga ggaaagttca atgacaaatt
     5161 ttgacattct tgacaatcaa tttttatcct tatctgaaaa tgaattatca gatattgatg
     5221 gcggtctcgc tcccttggtt atctttggag tagcagtatc ttggaaggct attgcaggtg
     5281 gaacagcact tataggttct ggtttggcag ctggttattt tttaggagga gattaatatg
     5341 atgaaagatt tgaacaatta tcgtgaaatt tctaataagg aattgcaaga aatcaagggt
     5401 ggctttggtg tcggtgttgg tatcgcttta tttatggcag gttataccat tggaaaagac
     5461 cttcgtaaaa agtttggtaa gtcatgctag ataagaaaca catttttaga aggataaatt
     5521 ttattgtctt catctcttac agtttgctca gcattctcaa tgatttgaac attactacca
     5581 tccctttacc attcgattta tctgtttgta ttgttttatt tttatgcttc aactctattt
     5641 ttgatcagaa caatgactcc cataaaaata ataagctttg aaaattccat tgtcatgtca
     5701 tgttagaaaa atgcaaagac cacctcatct tgatagatgg ggtggaattt tcgtgtcgta
     5761 aatctactat ctctacatcc ccaaacaaaa aaccccagca taagcagggc atctaagcat
     5821 ttaattcaaa gtaaaataca aaccaaacga cataggtcac gaggaggaga aaaagcgagt
     5881 agagagtcac aaaggtcatt ttccacaaga acttggtttg tcgtcgttcc agtttggcaa
     5941 atagaagatt ccccgcataa acgcaagcaa caaaaacaat aaaagctacc aagcgagctc
     6001 cgatagcaaa agcaaataag ttatacatag ggcaacctcc ttgacttaaa atctatatgg
     6061 aattatgaca agcaataaat ttcacttccg ttatcaacat aatacatttt ctttattctt
     6121 gcaaacgctt accaaagaaa tcgtccccta actttctcgt ttccgtcttt tactaatttt
     6181 tcattttgtg gtataattga aataattgta acgaatcaag gtcaatctag acacaaaatg
     6241 gaatgaaatc aagcaaatat ctgctaaaag tttggaataa gctgacctgt aaatagaaag
     6301 gaactatatg atttacaaag ttttttatca agaaacaaaa gaacgtagcc cacgccgtga
     6361 aacaacacgc gcactttacc tagacatcga tgccagctca gaacttgagg gtcgcatcac
     6421 tgctcgccaa cttgtcgaag aaaatcgccc agagtacaat atcgaatata tcgaactctt
     6481 gtctgacaaa ttgctcgatt acgaaaaaga aactggcgcc ttcgaaatca cggagttcta
     6541 atatggccta tactcttaaa cctgaagaag tcggcgtttt tgccatcggt ggtctgggag
     6601 aaatcgggaa aaacacttac ggaattgaat accaagacga gattatcatc gtcgatgctg
     6661 ggattaaatt cccagaagat gacttgcttg gtatcgacta tgtcattcct gactactctt
     6721 acatcgtgga caatatcgac cgcgtcaagg ctgttttaat cacacacgga cacgaggacc
     6781 acattggtgg gattccgttc ctactcaagc aagcaaatgt ccctatctac gctggaccgc
     6841 ttgccttggc tttgatccgt gggaaactcg aagaacacgg cctcttgcgc aacgccaaac
     6901 tttacgaaat caaccacaac accgagttga cctttaaaaa tctcaaggca actttcttta
     6961 gaacgactca ctctattcca gagcctttgg ggattgtcat tcatactcct caagggaaaa
     7021 tcgtctgtac gggtgacttt aagttcgact ttactccagt tggagaacct gcggacttgc
     7081 atcgtatggc tgcgcttggt gaagaaggcg tgctctgtct cctgtctgac tcgacaaatg
     7141 cggaagtacc aacctttacc aactctgaaa aagtcgttgg tcagtccatt atgaagatta
     7201 tccaaggtat tgaaggacgt atcatctttg catcctttgc ctcaaatatc ttccgtctcc
     7261 agcaggcaac agaagctgct gttaagactg gacgcaagat tgcggtcttt ggtcgttcta
     7321 tggaaaaggc cattgtcaac ggaatcgatc ttggctacat caaagctcct aagggaacct
     7381 ttatcgagcc aaatgaaatc aaagattatc ctgcaggaga agttcttatc ctctgtacag
     7441 gtagtcaggg tgagcctatg gcagctctct ctcgtatcgc caacggaacc caccgtcaag
     7501 tacaattaca accaggtgat accgttatct tctcttctag tcccatccct ggaaacacta
     7561 ctagcgtcaa caagctgatt aacatcattt ctgaagctgg tgtcgaagtt atccacggta
     7621 aagtgaacaa tatccataca tctggacacg gtggtcagca agagcaaaaa ctcatgctct
     7681 gcttgattaa gccaaaatac ttcatgcctg tccacggtga ataccgcatg caaaaagtcc
     7741 acgctggact agcagtggat actggtgttg agaaggacaa tatctttatc atgagcaatg
     7801 gcgatgtgct tgcccttact gctgactcag ctcgtatcgc aggtcatttc aacgcccaag
     7861 atatctatgt cgatggaaat cgtatcggtg aaattggcgc agctgtcctc aaagatcgtc
     7921 gcgatctatc tgaagacggt gtcgttctgg cagtcgcaac tgttgacttc aaatcgcaga
     7981 tgattctgtc tggtccagac atcctcagcc gaggctttgt ctacatgaga gagtctggcg
     8041 acttgattcg ccaaagccag cgtatcctct tcaatgccat tcgtatcgca ctgaaaaata
     8101 aggatgccag cgtgcaatct gtcaatggtg ccattgtcaa cgctattcgc cccttcctct
     8161 atgaaaatac cgaacgtgaa ccgatcatca tcccgatgat cctcacacca gatgaagaat
     8221 aaagcaagaa aacagccccg tcctcggagc tgtttttctc tatgctttct tttgagatta
     8281 aaactcatac tcaatgaaaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa
     8341 gcactgcttt gaggttgtag atagaactga cgaagtcagt agccatacct acggcaaggc
     8401 gacgttgacg cggtttgaag agattttcga agagtatcaa taaaaatcga aatcagacta
     8461 gaaggctaag cgaaagcata acttgagtta gctcccatag ttcgggaaac tatgggaggc
     8521 tggagatgaa tcaaagccaa gctttgaact cattcgtaag aagccgacga cgtatcattt
     8581 tgatttttga agagttttag aaatactacg atttttacct tccagataca ccatcaaaat
     8641 agaaatatct gctgggttta ctcccgaaat acggctggct tggccgatgg tttctggatt
     8701 gatgagtttg aacttctgac gggcttcggt tgcgatagaa tcaatgtcat cccagtcgat
     8761 attggccgga atgcgttttt cttccatgcg tttcatcttg gcaacctggt ccatggcttt
     8821 ggaaatatag ccttcatact tgatttctgt ttcaatcaat tcgataatct tgtcatccaa
     8881 gtcttctgca gctggtccga tgaaggccac cacatcttgg taagaaactt ctggacggcg
     8941 aaggaattcc ttggctgtca ctgcatcggt caagggtttg aagcccatct cctcaacctt
     9001 ggcattggtt tccttgactg gcttaagttt gatactgtct aggcgcttca tctcattatc
     9061 aaattgattt ttcttgattt caaaacgagc ccagcgttca tcgtccacaa ggccaatctc
     9121 gcgtcccatc tcagtcaagc gcatatcagc attgtcatga cgaagaatga gacggtattc
     9181 agcacgactg gtcaagagac ggtagggttc aatggttccc ttggtcacca agtcgtcgat
     9241 catcaccccg atataaccat cactgcgctt caaaatcaat tcaggcttgc cttggatttt
     9301 cagagccgca ttgatacccg cgataatccc ttggccagca gcttcttcgt aacctgatgt
     9361 tccatttgtc tgaccagcag tgaagagacc tgagattttc ttggtttcca aagtcgcacg
     9421 caactgatga ggcaagacca tatcatactc aatagcataa cctgtccgca tcatctctgc
     9481 attttccaaa cctttgatgg aatgaaccaa gtcacgctgg acatcctcag gcagactggt
     9541 tgaaagtcct tgaacataga cttcctcagt attgcgccct tctggctcaa ggaagagttg
     9601 gtgacgttcc ttgtccgcaa agcgcacaat cttgtcttca atcgacggac agtaacgagg
     9661 ccccactccc ttgaccacac ctgtaaacat aggcgcacgg tggaggttgt tttgaataat
     9721 ctcatgactg gtaccattgg tataggtcaa ccagcatggc acttggtcct tgacataatc
     9781 ctcatcacgt gaagtgtatg agaagtgatt aggcgcttca tctcctggtt ggatttctgt
     9841 cacgtcgtag ttgatagaag aggccttgac gcgtggaggg gttcctgtct tgaaacgacc
     9901 gatttcgaga cccagttcct tgagattgtc agctaggtta atagaagcca agctgtggtt
     9961 aggacctgat gagtacttga ggtctccgat gataatttcc ccacggagag cagtccctgt
    10021 cgtcacaata acagccttag cagcatattc ttgatgggtg gctgtacgca caccgacaac
    10081 cttgccatct tccaccaaaa tctcatcaat catggtttga cgaagggtca gattttcttg
    10141 gttttcaacc gtcttgcgca tctccttaga gtaaagttcc ttgtcagcct gcgcacgaag
    10201 ggcacggaca gctggcccct tccctgtgtt tagcatcttc atctggatgt aagtcttgtc
    10261 aatggttttg gccatctcgc caccgagggc atcgacttca cgcacgacaa tccccttggc
    10321 agaaccaccg atagagggat tacaaggcat gaaagccagc atttcaatat tgatggtcgc
    10381 aagcaggacc ttacagccca tacggctagc ggccaaggaa gcctcaaccc cagcgtgtcc
    10441 cgcaccaatt acaataatat cgtattcttc agtaaaatga taagtcatgt ttctctccta
    10501 ttcctcaaga tgaatgtgtc ttagttggcc ttcccaatct ggtagggctg tttttaaaaa
    10561 ggctggaact agctggatat tctggagctt atccaagtca atccactcac agggctgcct
    10621 tttctcatct tcctgcatgg tcaatggggc atcttcaagc aaatccacca gataatgaaa
    10681 ctcgatattg tgataggaaa caccgtattg ttcaaaacga ttttcaacca caaaagctag
    10741 ctgcccagct tgagctttaa cacccagttc ttccttcact tcacggacta ccgcgtcttc
    10801 cgtgctttca ttgacttgaa tcgcacctcc aatagtgtaa tacttgccct tgtctttggt
    10861 aactagaagc ttgtgatttt ggacaatcaa ggctgtcgcc cgaacaccaa aaaccgtatt
    10921 gtctactttt gtccgaaagt cttgttgagt cattcttgtc ctttccctta aacgacacaa
    10981 aaacagtcaa aactacaaag aagtgcagga caaaaaagcc tgcaacatcc atgagctttg
    11041 accatcattt ctattgctgt tattattgta gcaaattgag aaaatttgtc aatctaaatg
    11101 tactgacaaa cttgtccatc gcggtaagca ttgtcaatca aaccaccacc tagacactct
    11161 tcgccatcgt aaaagacaac tgcctgtcct ggtgtaatcg cgcgttgtgg ttccgcaaag
    11221 atgacctctg ccttgtctcc tttgacatgg acggtcacct tagagtcagg ctgacggtaa
    11281 cggaatttag ccgtacattc tagcgtaaac tcttctggca tttcacgagt aaagtggact
    11341 tgactggctt ctaggctagt tgacatgagc gaatcatggt agaatccttg tcctacatag
    11401 agaatattct tgcttagatc ttttccgaca acgaaccaag gggcattgtc accgccgtgt
    11461 tgcccaccga taccgagtcc gccacgctga ccgattgtat agtacataag acctgcatgc
    11521 tcgcccatat cgcgaccatc cacagtcatc atgcgaccag gctgagctgg caggtagttg
    11581 ctgaggaagt ttttaaagtt cttttctccg ataaagcaaa tccctgtcga gtctttcttc
    11641 ttagcagtcg aaaggcctgc ttcttctgct agttttcgaa cttcaggctt ttccaaatgt
    11701 cctagtggga acatggtttt ttgaagttgt tcttgcgaaa gttggctgag gaaataggtc
    11761 tggtccttgc cattgtccac gccacgaagc atgtgaacag tgccgtcctc atcacgcgcc
    11821 actcgagcat aatgcccagt cgctacatag tctgccccca aggttatggc atagtccaaa
    11881 aaggccttga acttgatttc cttgttgcac ataacgtccg gatttggcgt gcgccctgca
    11941 cggtattccg ctaggaaata ctcaaaaacg cggtcccagt actctttttc aaaattgaca
    12001 gagtagtagg gaatgccaat ctggtctgcc accgcaacca catccttgta atcttcggtc
    12061 gccgtacaga cgccgttttc atctgtgtca tcccagttct tcatgaagat accgatcaca
    12121 tcgtagccct gctccttgag caaaagagcc gtcaccgacg aatcaacacc accactcatc
    12181 cccacgacaa cacgtgtttt agagttatca ctcatggtaa gtctcccatc tattcgttta
    12241 ttcacgattg aaggtcgtgt gtgcttcacg attgaaggtc gcttgagcag tattcattat
    12301 aacacgcttg gttagagaag acaaggaaga gcttaaaaat tgttttttaa aacttatagt
    12361 caatatacag attatgtgaa tgacgtgagt ataccttctt cttatcttca ttcaaataac
    12421 tataataaat aaaacaaccc attttctcta atctattttt caagttagag aaaaggagtc
    12481 gttttttaat gacatttcct gaaatcataa gacaggtacc taaagaatac gaacataaat
    12541 ctattcaatc gaaccttatc tttgtttcaa aattaaaatg tcaaatgttc ttaacatgat
    12601 ttaatttaat cggcttaaac ccattcaccg ttttcattta cagtatatcc gtctacagtt
    12661 gtgttgactg caagggcacc taagcc
//
LOCUS       DAVLAQ010000052        12639 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000052 DAVLAQ010000000
VERSION     DAVLAQ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.052"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            9..1145
                     /gene="dnaN"
                     /locus_tag="VXB71_001603"
     CDS             9..1145
                     /gene="dnaN"
                     /locus_tag="VXB71_001603"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0451689.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1210..1404
                     /locus_tag="VXB71_001604"
     CDS             1210..1404
                     /locus_tag="VXB71_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0451690.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEVTRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1488..2603
                     /gene="ychF"
                     /locus_tag="VXB71_001605"
     CDS             1488..2603
                     /gene="ychF"
                     /locus_tag="VXB71_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0451691.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2675..3244
                     /locus_tag="VXB71_001606"
     CDS             2675..3244
                     /locus_tag="VXB71_001606"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0451692.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3245..6754
                     /gene="mfd"
                     /locus_tag="VXB71_001607"
     CDS             3245..6754
                     /gene="mfd"
                     /locus_tag="VXB71_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0451693.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            6812..7078
                     /locus_tag="VXB71_001608"
     CDS             6812..7078
                     /locus_tag="VXB71_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0451694.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7071..7439
                     /locus_tag="VXB71_001609"
     CDS             7071..7439
                     /locus_tag="VXB71_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0451695.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7559..8827
                     /locus_tag="VXB71_001610"
     CDS             7559..8827
                     /locus_tag="VXB71_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0451696.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8824..10101
                     /gene="tilS"
                     /locus_tag="VXB71_001611"
     CDS             8824..10101
                     /gene="tilS"
                     /locus_tag="VXB71_001611"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0451697.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10105..10647
                     /gene="hpt"
                     /locus_tag="VXB71_001612"
     CDS             10105..10647
                     /gene="hpt"
                     /locus_tag="VXB71_001612"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0451698.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10663..12621
                     /gene="ftsH"
                     /locus_tag="VXB71_001613"
     CDS             10663..12621
                     /gene="ftsH"
                     /locus_tag="VXB71_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0451699.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAHHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         4349 a         1909 c         2575 g         3806 t
ORIGIN      
        1 gagaatccat gattcatttt tcaattaata aaaatttatt tctacaagca ttaaatacta
       61 ctaagagagc tattagttct aaaaatgcca ttcctatttt atcaacagta aaaattgacg
      121 tgaccaatga aggtattact ttaattggtt caaatggtca aatttcaatt gaaaatttta
      181 tttctcaaaa aaatgaagat gctggtttgt taattacttc tttaggttcg atccttcttg
      241 aagcttcttt ctttatcaat gtagtatcta gtttacctga tgtgactctt gattttaaag
      301 aaattgaaca aaatcaaatt gttttaacca gtggcaaatc agaaattacc ctaaaaggaa
      361 aagatagcga acaatatcca cgaatccaag aaatttcagc aagcactcct ttaatacttg
      421 aaacaaaatt actcaagaaa attattaatg aaacagcctt tgctgcaagt acacaagaga
      481 gtcgtccgat tttaacaggt gtccacttcg tattgagtca acacaaagag ttaaaaacag
      541 ttgcaacaga ctctcatcgc ctaagccaga aaaaattgac tcttgaaaaa aatagtgatg
      601 attttgatgt cgtaattcct agccgttctc tacgcgaatt ttcagcggta tttacagatg
      661 atatcgaaac tgtagagatt ttctttgcca ataaccaaat cctctttaga agcgaaaata
      721 ttagcttcta tactcgtctc ctagaaggaa actatcctga tacagatcgc ttgattccaa
      781 cagactttaa cactactatt acttttaatg tggtaaactt acgccagtca atggagcgtg
      841 cccgtctttt atcaagtgcg actcaaaatg gtactgtgaa acttgaaatt aaggatgggg
      901 ttgttagcgc ccatgttcac tctccagaag ttggtaaagt aaacgaagaa atcgatactg
      961 atcaggttac tggtgaagat ttgaccatta gtttcaaccc aacttacttg attgattctc
     1021 ttaaagcttt aaatagcgaa aaggtgacca ttagctttat ctcagctgtt cgtccattta
     1081 ctcttgtgcc agcagatact gacgaagact tcatgcagct cattacacca gttcgtacaa
     1141 attaagtgaa agaggttgag cctggctcgc ctcttttatg atataatcga aaaagaaaag
     1201 gagagtagta tgtatcaagt tggaaatttt gttgagatga aaaaatcaca cgcttgtaca
     1261 atcaagtcga ctggtaaaaa ggctaatcgt tgggaagtta cacgtgtagg agcagatatc
     1321 aaaataaaat gcagtaattg tgagcatgtt gtcatgatgg ggcgatatga ttttgagcga
     1381 aaaatgaata aaattattga ctgagaaccc ttagttagag ggttagcact ttatcccttt
     1441 ttgtgttata atattaggga ttgaaatgaa aacggagaat gagaaatatg gctttgacag
     1501 caggtatcgt tggtttgcca aacgttggta aatcaacatt atttaatgca attacaaaag
     1561 caggagcaga ggcagcaaac tacccatttg cgactattga tccaaatgtt ggaatggtgg
     1621 aagttccaga tgaacgccta caaaaactaa ctgaaatgat aactcctaaa aagacagttc
     1681 ccacaacatt tgaatttaca gatattgcag ggattgtaaa aggagcttca aaaggagaag
     1741 ggctagggaa taaattcttg gccaatattc gtgaagtaga tgcgattgtt cacgtagttc
     1801 gtgcttttga tgatgaaaat gtgatgcgcg agcaaggacg tgaagacgcc tttgtagatc
     1861 cacttgcaga tattgataca attaatctgg aattgattct tgctgactta gaatcagtga
     1921 acaaacgata tgcgcgtgta gaaaagatgg cacgtacgca aaaagataaa gaatcagtag
     1981 cagaattcaa tgttcttcaa aagattaaac cagtcctaga agacgggaaa tcagctcgta
     2041 ccattgaatt tacagatgag gaacaaaagg ttgtcaaagg tcttttcctt ttgacgacta
     2101 aaccagttct ttatgtagct aatgtggacg aggatgtggt ttcagaacct gactctatcg
     2161 actatgtcaa acaaattcgt gaatttgcag cgacagaaaa tgctgaagta gtcgttattt
     2221 ctgcgcgtgc tgaggaagaa atttctgaat tggatgatga agataaaaaa gagtttcttg
     2281 aagccattgg tttgacagaa tcaggtgtag ataagttgac gcgtgcagct taccacttgc
     2341 ttggattggg aacttacttc acagctggtg aaaaagaagt tcgcgcttgg actttcaaac
     2401 gtggtatgaa ggctcctcaa gcagctggta ttatccactc agactttgaa aaaggcttta
     2461 ttcgtgcagt aaccatgtca tatgaagatc tagtgaaata cggatctgaa aaggccgtaa
     2521 aagaagctgg acgcttgcgt gaagaaggaa aagaatatat cgttcaagat ggcgatatca
     2581 tggaattccg ctttaatgtc taaaaattaa taaatggtgt caattaggtt ggaaaaaaaa
     2641 ttccaaccct tttggctttt gaaaggaaaa ataaatgacc aaattacttg taggcttggg
     2701 aaatccaggg gataaatatt ttgaaacaaa acacaatgtt ggttttatgt tgattgatca
     2761 actagcgaag aaacagaatg tcacttttac acacgataag atatttcaag ctgacctagc
     2821 atcctttttc ctaaatggag aaaaaattta tctggttaaa ccaacgacct ttatgaatga
     2881 aagtggaaaa gcagttcatg ctttattaac ttactatggt ttggatattg acgatttact
     2941 tatcatttac gatgatcttg acatggaagt tgggaaaatt cgtttaagag caaaaggctc
     3001 agcaggtggt cataatggta tcaagtctat tattcaacat ataggaactc aggtctttaa
     3061 ccgtgttaag attggaattg gaagacctaa aaatggtatg tcagttgttc atcatgtttt
     3121 gagtaagttt gacagggatg attatatcgg tattttacag tctattgaca aagttgacga
     3181 ttctgtaaac tactatttac aagagaaaaa ttttgagaaa acaatgcaga ggtataacgg
     3241 ataaatggtg accttattag atttattctc agaaaatgat cagattaaaa aatggcatca
     3301 aaatttaaca gataagaaaa gacaactaat acttggttta tcaacatcta ctaaggctct
     3361 tgcaattgca agcagtttag aaaaagaaga taggattgtg ttattgacgt caacttatgg
     3421 agaagcagaa ggacttgtta gtgatcttat atctatcttg ggtgaggaac tcgtctatcc
     3481 atttttggta gatgatgctc ctatggtgga gtttttgatg tcttcacagg aaaaaattat
     3541 ttcacgggtt gaagccttgc gttttttgac tgattcatct aagaaaggga ttttagtttg
     3601 taatatcgta gcaagtcgat tgattttacc gtctcccaat gcattcaaag atagtattgt
     3661 aaaaatctca gttggtgaag aatatgatca acacgcgttt atccatcagt taaaggaaaa
     3721 tggctatcga aaagttactc aagtacaaac tcagggcgaa tttagtcttc gaggagatat
     3781 tttagatatt tttgaaatat cccagttaga accttgtcga attgagtttt ttggtgatga
     3841 aattgatggt atcaggtcat ttgaagtaga aacacaatta tcgaaagaaa ataagacaga
     3901 actcactatc tttccagcta gtgatatgct tttgagagaa aaggattatc aacgaggaca
     3961 gtcagcttta gaaaaacaaa tttcaaaaac tttatcacct attttgaaat catacctaga
     4021 agaaattctt tcaagttttc accaaaaaca aagtcatgca gactctcgga agtttttatc
     4081 tttgtgctat gataagacat ggactgtctt tgattatatt gaaaaagata ccccaatatt
     4141 ctttgatgat tatcaaaaat tgatgaatca gtatgaagtc tttgaaagag acttagcgca
     4201 gtactttaca gaagaattac agaatagtaa agcattttct gatatgcagt atttttctga
     4261 tattgaacaa atctataaaa aacaaagtcc agtgaccttt ttctctaatc ttcaaaaggg
     4321 tttaggaaat ctcaaatttg acaaaattta tcaattcaat caatatccta tgcaggaatt
     4381 tttcaatcag ttttcttttc taaaagaaga aattgaacga tataaaaaaa tggattacac
     4441 cattattctg cagtctagca attcaatggg aagtaaaaca ttggaggata tgttagagga
     4501 atatcagatt aaattggatt ctagagataa gacaaatatc tgtaaagaat ctgtaaactt
     4561 aatagagggt aatctcagac atggttttca ttttgtagat gaaaagattt tattgataac
     4621 tgaacatgag atttttcaaa agaaattaaa gcgtcgtttt cgaagacaac atgtttcaaa
     4681 tgcagagaga ttaaaagatt acaatgaact tgaaaaaggg gactatgttg tccatcatat
     4741 ccatgggatt ggtcaatatc taggaattga aaccattgaa atcaagggaa ttcatcgcga
     4801 ttatgtcagt gtccaatacc aaaatggtga tcaaatttct atccccgtgg aacagattca
     4861 tctactgtcc aaatatattt caagtgatgg taaagctcca aaactcaata aattaaatga
     4921 cggtcatttt aaaaaggcca agcaaaaggt taagaaccag gtagaggata tagctgatga
     4981 tttaatcaaa ctctactctg aacgtagtca gttgaagggt tttgctttct cagctgatga
     5041 tgatgatcaa gatgcctttg atgatgcttt cccttatgtt gaaacggatg atcaacttcg
     5101 tagtattgag gaaatcaaga gggatatgca ggcttctcag ccaatggatc gacttttagt
     5161 tggggatgtt ggttttggaa agactgaagt tgctatgcgt gcagccttta aagcagtcaa
     5221 tgatcacaaa caggttgtca ttctagttcc gacgacggtt ttagcgcaac agcactatac
     5281 gaattttaag gaacgattcc aaaattttgc agttaatatt gatgtgttga gtcgctttag
     5341 aagtaaaaaa gagcagactg caacacttga aaaattgaaa aacggtcaag tcgatatttt
     5401 gattggaaca catcgtgttt tgtcaaaaga tgttgtgttt gctgatttgg gcttgatgat
     5461 tattgatgag gaacagcgat ttggtgtcaa gcataaggaa actttgaaag aactgaagaa
     5521 acaagtggat gtcctaacct tgaccgctac gccaatccct cgtaccctcc atatgtctat
     5581 gctgggaatc agagatttat ctgttattga aactccgccg actaatcgct atcctgttca
     5641 gacctatgtt ttggaaaaga atgatagtgt cattcgtgat gctgtcttgc gtgaaatgga
     5701 gcgtggaggt caagtttatt atctttacaa caaagttgac acaattgttc agaaggtttc
     5761 agaattacag gagttgattc cggaggcttc gattggatat gttcatggtc gaatgagtga
     5821 agtccagttg gaaaatactc tattagactt tattgaggga caatacgata tcttggtgac
     5881 gactactatt attgagacag gggtggacat tccaaatgct aatactttat ttattgaaaa
     5941 tgcggaccat atgggcttgt caaccttata tcagttaaga ggaagagtcg gtcgtagtaa
     6001 tcgtattgct tatgcttatc tcatgtatcg tccagaaaaa tcaatcagtg aagtctctga
     6061 aaagagatta gaagcgatta aaggatttac agaattgggc tctggcttta agattgcaat
     6121 gcgagatctt tcgattcgtg gagcaggaaa tcttttagga aaatcccagt ctggtttcat
     6181 tgattctgtt ggttttgaat tgtattcgca gttattagag gaagctattg ctaaacgaaa
     6241 cggtaatgct aacgctaaca caagaaccaa agggaatgct gagttgattt tgcaaattga
     6301 tgcctatctt cctgatactt atatttctga tcaacgacat aagattgaaa tttacaagaa
     6361 aattcgtcaa attgacaacc gtgtcaatta tgaagagtta caagaggagt tgatagaccg
     6421 ttttggagaa tacccagatg tagtagccta tcttttagag attggtttgg ttaaatcata
     6481 cttggacaag gtctttgttc aacgtgtgga aagaaaagat aataaaatta caattcaatt
     6541 tgaaaaagtc actcaacggc tgtttttagc tcaagattat tttaaagctt tatccgtaac
     6601 gaacttaaaa gcaggcatcg ctgagaataa gggattaatg gagcttgtat ttgatgtcca
     6661 aaataagaaa gattatgaaa ttttagaagg tctgctgatt tttggagaaa gtttattaga
     6721 gataaaagag tttaaggaag aaaattccat ttgatatttt tcttctataa aatagataaa
     6781 aatggtacaa taataaattg aggtaataag gatgagatta gataaatatt taaaagtatc
     6841 gcgaattatc aagcgtcgta cagtcgcaaa ggaagtagca gataaaggta gaatcaaggt
     6901 taatggaatc ttggccaaaa gttcaacgga cttgaaagtt aatgaccaag ttgaaattcg
     6961 ctttggcaat aagttgctgc ttgtaaaagt actagagatg aaagatagta caaaaaaaga
     7021 agatgcagca ggaatgtatg aaattatcag tgaaacacgg gtagaagaaa atgtctaaaa
     7081 atattgtaca attgaataat tcttttattc aaaatgaata ccaacgtcgt cgctacctga
     7141 tgaaagaacg acaaaaacgg aatcgtttta tgggaggggt attgattttg attatgctat
     7201 tatttatctt gccaactttt aatttagcgc agagttatca gcaattactc caaagacgtc
     7261 agcaattagc agacttgcaa actcagtatc aaactttgag tgatgaaaag gataaggaga
     7321 cagcatttgc taccaagttg aaagatgaag attatgctgc taaatataca cgagcgaagt
     7381 actattattc taagtcgagg gaaaaagttt atacgattcc tgacttgctt caaaggtgat
     7441 aaaatggaaa atttattaga cgtaatagag caatttttga gtttgtcaga tgaaaagctg
     7501 gaagaattgg ctgataaaaa tcaattattg cgtttacaag aagaaaagga aaggaagaat
     7561 gcgtaaattc ttaattattt tgttgctacc aagttttttg accatttcaa aagtcgttag
     7621 cacagaaaaa gaagtcgtct atacttcgaa agaaatttat tacctttcac aatctgactt
     7681 tagtatttat tttagagaaa aattaagttc tcccatggtt tatggagagg ttcctgttta
     7741 tgcgaatgaa gatttagtag tggaatctgg gaaattgact cccaaaacaa gttttcaaat
     7801 aaccgagtgg cgcttaaata aacaaggaat tccagtattt aagctatcaa atcatcaatt
     7861 tatagctgcg gacaaacgat ttttatatga tcaatcagag gtaactccaa caataaaaaa
     7921 agcatggtta gaatctgact ttaaactgta caatagtcct tatgatttaa aagaagtgaa
     7981 atcatcctta tcagcttatt cgcaagtatc aatcgacaag accatgtttg tagaaggaag
     8041 agaatttcta catattgatc aggctggatg ggtagctaaa gaatcaactt ctgaagaaga
     8101 taatcggatg agtaaagttc aagaaatgtt atctgaaaaa tatcagaaag attctttctc
     8161 tatttatgtt aagcaactga ctactggaaa agaagctggt atcaatcaag atgaaaagat
     8221 gtatgcagcc agcgttttga aactctccta tctctattat acgcaagaaa aaataaatga
     8281 gggtctttat cagttagata cgactgtaaa atacgtatct gcagtcaatg attttccagg
     8341 ttcttataaa ccagagggaa gtggtagtct tcctaaaaaa gaagataata aagaatattc
     8401 tttaaaggat ttaattacga aagtatcaaa agaatctgat aatgtagctc ataatctatt
     8461 gggatattac atttcaaacc aatctgatgc cacattcaaa tccaagatgt ctgccattat
     8521 gggagatgat tgggatccaa aagaaaaatt gatttcttct aagatggccg ggaagtttat
     8581 ggaagctatt tataatcaaa atggatttgt gctagagtct ttgactaaaa cagattttga
     8641 tagtcagcga attgccaaag gtgtttctgt taaagtagct cataaaattg gagatgcgga
     8701 tgaatttaag catgatacgg gtgttgtcta tgcagattct ccatttattc tttctatttt
     8761 cactaagaat tctgattatg atacgatttc taagatagcc aaggatgttt atgaggttct
     8821 aaaatgaggg aaccagattt tttaaatcat tttctcaaga agggatattt caaaaagcat
     8881 gctaaggcgg ttctagctct ttctggtgga ttagattcca tgtttctatt taaggtattg
     8941 tctacttatc aaaaagagtt agagattgaa ttgattctag ctcatgtgaa tcataagcag
     9001 agaattgaat cagattggga agaaaaggaa ttaaggaagt tggctgctga agcagagctt
     9061 cctatttata tcagcaattt ttcaggagaa ttttcagaag cgcgtgcacg aaattttcgt
     9121 tatgattttt ttcaagaggt catgaaaaag acaggtgcga cagctttagt cactgcccac
     9181 catgctgatg atcaggtgga aacgattttg atgcgcttga ttcgaggaac tcgcttgcgc
     9241 tatctatcag gaattaagga gaagcaagta gtcggagaga tagaaatcat tcgtcccttc
     9301 ttgcattttc agaaaaaaga ctttccatca atttttcact ttgaagatac atcaaatcag
     9361 gagaatcatt attttcgaaa tcgtattcga aattcttact taccagaatt ggaaaaagaa
     9421 aatcctcgat ttagggatgc aatcttaggc atcggcaatg aaattttaga ttatgatttg
     9481 gcaatagctg aattatctaa caatattaat gtggaaaatt tacagcagtt attttcttac
     9541 tctgagtcta cacaaagagt tttacttcaa acttatctga atcgttttcc agatttgaat
     9601 cttacaaaag ctcagtttgc tgaagttcag cagattttaa aatctaaaag ccagtatcgt
     9661 catccgatta aaaatggcta tgaattgata aaagagtacc aacagtttca gatttgtaaa
     9721 atcagtccgc aggctgatga agaggaagat gaacttgtgt tacactatca aaatcaggta
     9781 gcttatcaag gatatttatt ttcctttgga cttccattag aaggtgaatt aattcaacaa
     9841 atacctgttt cacgtgaaac atccatacac attcgtcatc gaaaaacagg agatgttttg
     9901 attcaaaatg ggcatagaaa aaaactcaga cgtttattta ttgatttgaa aatccctatg
     9961 gaaaagagaa actctgctct tattattgag caatttggtg aaattgtctc aattttggga
    10021 attgcgacca ataatttgag taaaaaaacg aaaaatgata taatgaacac tgtactttat
    10081 atagaaaaaa tagataggta aaaaatgtta gaaaacgata ttaaaaaagt cctcgtttca
    10141 cacgatgaaa ttacagaagc agctaaaaaa ctaggtgctc aattaactaa agactatgca
    10201 ggaaaaaatc caatcttagt tgggatttta aaaggatcta ttccttttat ggctgaattg
    10261 gtcaaacata ttgatacaca tattgaaatg gacttcatga tggtttctag ctaccatggt
    10321 ggaacagcaa gtagtggtgt tatcaatatt aaacaagatg tgactcaaga tatcaaagga
    10381 agacatgttc tatttgtaga agatatcatt gatacaggtc aaactttgaa gaatttgcga
    10441 gatatgttta aagaaagaga agcagcttct gttaaaattg caaccttgtt ggataaacca
    10501 gaaggacgtg ttgtagaaat tgaggcagac tatacctgct ttactatccc aaatgagttt
    10561 gtagtaggtt atggtttaga ctacaaagaa aattatcgta atcttcctta tattggagta
    10621 ttgaaagagg aagtgtattc aaattagaaa gaataatctt taatgaaaaa acaaaataat
    10681 ggtttaatta aaaatccttt tctatggtta ttatttatct ttttccttgt gacaggattc
    10741 cagtatttct attctgggaa taactcagga ggaagtcagc aaatcaacta tactgagttg
    10801 gtacaagaaa ttaccgatgg taatgtaaaa gaattaactt accaaccaaa tggtagtgtt
    10861 atcgaagttt ctggtgtcta taaaaatcct aaaacaagta aagaaggaac aggtattcag
    10921 tttttcacgc catctgttac taaggtagag aaatttacca gcactattct tcctgcagat
    10981 actaccgtat cagaattgca aaaacttgct actgaccata aagcagaagt aactgttaag
    11041 catgaaagtt caagtggtat atggattaat ctactcgtat ccattgtgcc atttggaatt
    11101 ctattcttct tcctattctc tatgatggga aatatgggag gaggcaatgg ccgtaatcca
    11161 atgagttttg gacgtagtaa ggctaaagca gcaaataaag aagatattaa agtaagattt
    11221 tcagatgttg ctggagctga ggaagaaaaa caagaactag ttgaagttgt tgagttctta
    11281 aaagatccaa aacgattcac aaaacttgga gcccgtattc cagcaggtgt tcttttggag
    11341 ggacctccgg ggacaggtaa gactttgctt gctaaggcag tcgctggaga agcaggtgtt
    11401 ccattcttta gtatctcagg ttctgacttt gtagaaatgt ttgtcggagt tggagctagt
    11461 cgtgttcgct ctctttttga ggatgccaaa aaagcagcac cagctatcat ctttatcgat
    11521 gaaattgatg ctgttggacg tcaacgtgga gtcggtctcg gcggaggtaa tgacgaacgt
    11581 gaacaaacct tgaaccaact tttgattgag atggatggtt ttgagggaaa tgaagggatt
    11641 atcgtcatcg ctgcgacaaa ccgttcagat gtacttgatc ctgccctttt gcgtccagga
    11701 cgttttgata gaaaagtatt ggttggccgt cctgatgtta aaggtcgtga agcaatcttg
    11761 aaagttcacg ctaagaacaa gcctttagca gaagatgttg atttgaaatt agtggctcaa
    11821 caaactccag gctttgttgg tgctgattta gagaatgtct tgaatgaagc agctttagtt
    11881 gctgctcgtc gcaataaatc gataattgat gcttcagata ttgatgaagc agaagataga
    11941 gttattgctg gaccttctaa gaaagataag acagtttcac aaaaagaacg agaattggtt
    12001 gctcaccatg aggcaggaca taccattgtt ggtctagtct tgtcgaatgc tcgcgttgtc
    12061 cataaggtta caattgtacc acgcggccgt gcaggcggat acatgattgc acttcctaaa
    12121 gaggatcaaa tgcttctatc taaagaagat atgaaagagc aattggctgg cttaatgggt
    12181 ggacgtgtag ctgaagaaat tatctttaat gtccaaacta caggagcttc aaacgacttt
    12241 gaacaagcga cacaaatggc acgtgcaatg gttacagagt acggtatgag tgaaaaactt
    12301 ggcccagtac aatatgaagg aaaccatgct atgcttggtg cacagagtcc tcaaaaatca
    12361 atttcagaac aaacagctta tgaaattgat gaagaggttc gttcattatt aaatgaggca
    12421 cgaaataaag ctgctgaaat tattcagtca aatcgtgaaa ctcacaagtt aattgcagaa
    12481 gcattattga aatacgaaac attggatagt acacaaatta aagctcttta cgaaacagga
    12541 aagatgcctg aagcagtaga agaggaatct catgcactat cctatgatga agtaaagtca
    12601 aaaatgaatg acgaaaaata accctgagag aggctggag
//
LOCUS       DAVLAQ010000053        12412 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000053 DAVLAQ010000000
VERSION     DAVLAQ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.053"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            94..363
                     /gene="blpJ"
                     /locus_tag="VXB71_001614"
     CDS             94..363
                     /gene="blpJ"
                     /locus_tag="VXB71_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV0451700.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSL"
     gene            432..680
                     /gene="blpK"
                     /locus_tag="VXB71_001615"
     CDS             432..680
                     /gene="blpK"
                     /locus_tag="VXB71_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEV0451701.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            924..1073
                     /gene="blpO"
                     /locus_tag="VXB71_001616"
     CDS             924..1073
                     /gene="blpO"
                     /locus_tag="VXB71_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0451702.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1177..1296
                     /locus_tag="VXB71_001617"
     CDS             1177..1296
                     /locus_tag="VXB71_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0451703.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1764..2135
                     /locus_tag="VXB71_001618"
     CDS             1764..2135
                     /locus_tag="VXB71_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451704.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            2764..3147
                     /locus_tag="VXB71_001619"
     CDS             2764..3147
                     /locus_tag="VXB71_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0451705.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3199..3888
                     /locus_tag="VXB71_001620"
     CDS             3199..3888
                     /locus_tag="VXB71_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0451706.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            3930..4163
                     /locus_tag="VXB71_001621"
     CDS             3930..4163
                     /locus_tag="VXB71_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451707.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4314..4925
                     /locus_tag="VXB71_001622"
     CDS             4314..4925
                     /locus_tag="VXB71_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0451708.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            5086..5880
                     /locus_tag="VXB71_001623"
     CDS             5086..5880
                     /locus_tag="VXB71_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0451709.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5877..6512
                     /gene="trmB"
                     /locus_tag="VXB71_001624"
     CDS             5877..6512
                     /gene="trmB"
                     /locus_tag="VXB71_001624"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0451710.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6638..7117
                     /gene="rimP"
                     /locus_tag="VXB71_001625"
     CDS             6638..7117
                     /gene="rimP"
                     /locus_tag="VXB71_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0451711.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7161..8297
                     /gene="nusA"
                     /locus_tag="VXB71_001626"
     CDS             7161..8297
                     /gene="nusA"
                     /locus_tag="VXB71_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0451712.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8319..8612
                     /locus_tag="VXB71_001627"
     CDS             8319..8612
                     /locus_tag="VXB71_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0451713.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8605..8904
                     /locus_tag="VXB71_001628"
     CDS             8605..8904
                     /locus_tag="VXB71_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0451714.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8921..11713
                     /gene="infB"
                     /locus_tag="VXB71_001629"
     CDS             8921..11713
                     /gene="infB"
                     /locus_tag="VXB71_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0451715.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11964..12314
                     /gene="rbfA"
                     /locus_tag="VXB71_001630"
     CDS             11964..12314
                     /gene="rbfA"
                     /locus_tag="VXB71_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0451716.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3796 a         2130 c         2786 g         3700 t
ORIGIN      
        1 ttaagaaaat caaaaagata ctaaaaaaaa tctatttgtt tattgaattt aagactttgg
       61 taacaaattg aaaataaaaa ggaggtattc atcatgaata caaaaatgtt gtcacagtta
      121 gaggttatgg atactgaaat gcttgcgaaa gttgaagggg ggtatagctc cactgattgt
      181 caaaatgcac tgattacagg agtcactacg ggaattataa ctggtggaac tggagcaggt
      241 ttggccactt taggagtagc tggacttgct ggtgcatttg ttggagcaca cattggtgca
      301 attgggggtg gattaacatg cttaggaggt atggttggtg ataaattggg actaagtttg
      361 taagacttat agtaaaatta tgaggattct attctgattt attttagttt tttaaaaaag
      421 gagtatttgt catggataca aaaatgatgt cacaattttc tgttatggat actgaaatgc
      481 ttgcttgcgt tgaaggtggc ggatgcaatt ggggagattt tgccaaagca ggtgttggag
      541 gagcagctgt agttgctgct ttaggttgtg cagcgggtgg agtgaaatat gggaaaattc
      601 taggaccatg gggcgctgca ataggaggaa ttggaggagc agtggtttgt ggatatttag
      661 cctataccgc tacatcataa aaatgaaagc taaattttat gaaggctata ttctttatta
      721 ttctcttcgc ttttcaaacc tatcttattt atctatccat aagtatctct gataaaaaac
      781 aaaagactat tgaattaaca tcattgaatt gttttgtcat attatttcta atctatgata
      841 aattaatttt tctctttatt gcctatgttt ttttgataat ttttatatta aacttgttcc
      901 gtaactgaaa agtgacatac tatatgaata caaaaatgat gtcacaattt tctgttatgg
      961 ataatgaaat gcttgcttgc gttgaaggtg gagatattga ttggggaaga aaaattagtt
     1021 gtgcagcagg ggttgcatat ggcgcaattg atgggtgtgc aacaacggtt tgacatttct
     1081 attgggacca tttgctatag gaataggtgt aactggtgct gcaggtggag ctatacttgg
     1141 aggtgtagcc tatgcagcaa catgttggtg gtaattatgg attttaaaag ttttattatt
     1201 ggtttagtag ttggtatatt tggtccttat atggatgact taattagaaa aatattttca
     1261 aaatcttcca aaaaggatac ggatagtact ctctaaaaaa taaatttctc ccctgtattt
     1321 gctagcttaa tttacagggg agtttcttta atattgtttc gcctgtcaaa atgatatgtg
     1381 atagcaggat gaaaagtcta caaacaagtt ggtatcaata caatataaag aggaaagtat
     1441 gtttttcatg cttgcttttt taatttttac aattcaagag gttttgatga ccatttatga
     1501 tttgagtgat ccaaggtcaa aataagtgct atactagcag tgtaaatgtt cttgctcaac
     1561 taagataaat cgcacattta ggaggaaaac ttatgaagaa aaaaatactg attattttcg
     1621 ttctgtatct gatcatgtcc atctttcttt atccgcttag ggagagtatt tggtataatc
     1681 tattttatac catagcctat atgattgcgg ttatgatcta tttttcttta attaaaaaga
     1741 aagaaaagaa atgaaagatt ttcttgatta aaaagaatca tattctttgt gagattgttc
     1801 ctgggtcagt tgcctttgct tgtttctact tatctatttc tatttcgtca gttttccaat
     1861 ttcttttagt agttattaac ttgacttcta ttttggttac tgtttatctt actagggaaa
     1921 tgagattaag agagtttgaa gatgatgatt tggttagtcc tagaaccaat caactcatgt
     1981 ttatcggctt gacaggcttt atgtctatta tttgtttgta tagaggtatc acagcaggag
     2041 aatcttatca acaactaatc gcttatattg gtgctattct ttgcttgatc atcatgcttc
     2101 tactcatttg gggtttgaag tattataaaa agtaggggct aatgaagttt ttgcaattta
     2161 ggaggtttcg atgacaattc aagatttgga tgaaaaattt taaaaaacaa tgatatacta
     2221 aacttgtcaa agttgcaacg ggtgctgcta cattatgtta aaaatcgctc ttgattgata
     2281 agttggattt gttaggaaag gagtaaataa ttatggataa gaaaaagata gtttcgacta
     2341 taatatgtat agtatttctt gtagtgtcag tagataattt ttttagagac ttaaccccgt
     2401 tactgttcat tttaaatatt attggcctgt cttgcttttc agtgctaaca tacattaaca
     2461 taaaagagat actcttaaat ataagtaaat gatgatttgg ttagtcctag aaccaatcaa
     2521 cttatgttta tcggcttggc agattttatg tttgtcattt gtttgtatag aggtatttca
     2581 gaaacagaat tctatcaaca actaatcgct tatataggtg tattctctgc ttgtttatca
     2641 cgcttctgct catgtggggc ttgaagtatt ataaaaagta gctttctatc cttttctgac
     2701 aggatatttg agtagaaggc tctattaaat tgttagtgaa ataaatgaat ggaggtattt
     2761 aatatgaaat acagattatt ttttgttatt ttcttgagta gtgtgttgga tattctttta
     2821 gggacatttt tacaaatctc tatcgtatct attgggtggc ttgttcttta cagtggtttg
     2881 tttgaagcag gagttttcct tcttgctaat aaaggggtgg cggtaaaaat caaggaagta
     2941 gatattcgaa atcgctttaa atttattttt ggaaaaacct tatggtttca aattcttttg
     3001 ctcatctttt tgataatcaa actttatctt ggtttggatg cgaggttgat tttattctat
     3061 ggacatattt tcattgtctt taatgcctta atgtatctat tatctagtag tcaggttagc
     3121 cttaaaaaaa acaaactgtc ttcttaatct tacagcagta gagcctgaca aggtgaggtc
     3181 atagtaggga ggatttctat gaaaaagtat caacttctat tcaaaataag tgcagttttc
     3241 tcttacttat ttttcgtatt tggtctttct cagatgacgc ttattattca aaattattgg
     3301 caattttctt cccagattgg caatttcgtc tggattcaaa atttcttgag tttgctattt
     3361 agcggagtca tgatttggat tctggttaag acaggtcatg gttatctctt tcacattcca
     3421 agaaaaaaat ggctttggta ttcgattttg acagtattag tggtagtgct ccagatctct
     3481 tttaacgttc agacagctaa acatgttcag tcaactgctg aaggttgggc tgtattgatc
     3541 ggttatagtg ggaccaactt tgctgagcta ggtatctata taactttgtt ctttctgact
     3601 ccacttatgg aagagctaat ctatagagga ttactgcaac acgccttttt taagcattcg
     3661 agatttggcc ttgatttgct tcttccgtca attttatttg ctcttcctca tttttcaagc
     3721 ctgcctagtt tgttagatat cttcatcttt gcaacatctg gcatcatctt tgctagtttg
     3781 acccgctata ccaagagcat ttatccttcc tatgcggtgc atgtgatcaa taatattttc
     3841 gcaacattac catttttgct gactttttta catagggtct tggggtaaaa aaacaaaagg
     3901 cttgcttttc agccatagag gagattatca tgtataaaca cttatttttc ctagattcca
     3961 aaactttaga tcggttgaca ccctatattc tagtcttggc ttctgacacc attgctttta
     4021 atgtttttgt gctaaccttt gtatctgcgg tggtttttaa tttcctaaat tccatgctag
     4081 ctttaatggc tatattcata ggggctggct atgtggtcgg attttggtta ctaatactca
     4141 atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt acggcaaggc
     4201 gacgttgacg tggtttgaat ttgattttcg aagagtataa aatggtttgt tttggaaagg
     4261 ctagaactaa agaatgacgc gtaggaagtc tgtttggtga ggaggatagt tttatggagt
     4321 tttttgataa atttcatgcc ttgtgttttg gatttttagt actaataatt gtcattacag
     4381 ttccttatac gattaaccat gggggttttt ttcaaaatga atctgcattg attcttgtaa
     4441 gtcttcttgt aacctcgctg agtgttgctt atgctagaaa gtttgaaatg atttcttttg
     4501 ggatgttaag caagaaacaa cttttgcttt tcattgcaat ctttcttcta agtgtacttg
     4561 agacgctggt ttatattcat ttcttcgctg tttcttctgg ctcaggggtc caacacttgg
     4621 cggaagtcag cagaggaatt tccctgtctt tgattttgac tacctcagtt tttggcccca
     4681 tccaggagga actcattttc agaggacttc ttcaaggtgc ggtttttgac aattcttggt
     4741 tagggcttgt gctaacttcc tctctctttt ctttcatgca tggaccttct aatgtccctt
     4801 cgtttatttt ttatctactt gggggtttgt tgctgggctt tgcttataaa aagagtcaaa
     4861 acctatgggt ttctactcta gtccacatgt tttacaacag ttggccactc ctatattatt
     4921 tataaaaatt atgaaaaggt aagcagaaga tggtgcttac ctttttcaag ctataatgat
     4981 acccaagcca atccagaggc ttttctttga gaatcgggtt agagtggttg acgaataggc
     5041 caaaaactag tagaatagta aggaaacttt atacggagga aagaaatgga tttgggtgat
     5101 aatgagctaa cactgactcc catacctggg aaaagtggca aggcttatat gggtagctat
     5161 cctgacggga agcgcatctt tgtaaaaatg aacacctctc caatcctacc tggtctagct
     5221 agagaacaaa ttgctccaca attattatgg agtcgtcgtt tggcagatgg gcgtgatatg
     5281 tgtgctcaag aatggttgac aggcaagata ttgaccccct atgatatgaa tcgtaagcaa
     5341 atcgtcaata ttttaacccg tcttcatcgc tcacgtccgt tgatgacaca attgagtcgt
     5401 ttgggctatg ccatggaaac acctgtagat ttactacagt cttggcagga aacggctcca
     5461 gatgctttgc gtaaaaatca ttttatcagt gaagtgatgg ctgatttacg tcagactatt
     5521 ccaggattta gagaggacca tgcgaccatt gtccatggag atgtacgaca tagtaattgg
     5581 attgagacag atagtggctt gatttattta gtagattggg attcggttcg cttgaccgat
     5641 cgcatgtttg atgtggccca tatgctctgc cattatattt cagaacatca gtggaaggaa
     5701 tggttgacct actacggtta caagtacaat caaacggtat taagtaaatt gtattggtat
     5761 ggtcaattgt cttatttgag tcagatttcc aagtattata tgaaccaaga tttagaaaat
     5821 gtcaatcggg agattcatgg tttgcgtcat ttccgagaca agtatggaaa gagaagatga
     5881 gagttagaaa tcgtaaaggg gcaacagaat tactagaggc aaatccccag tatgtggtcc
     5941 tcaatccctt ggaagccaag gcaaaatggc gggacttgtt tggcaatgat aatcccattc
     6001 atgtggaagt tggaagtgga aagggtgcct ttgtttcagg tatggccaag caaaaccctg
     6061 acatcaacta tatcgggatt gatattcaaa agtctgtttt gagctacgct ttggacaagg
     6121 tgcttgaagt tggagtgcct aacatcaagc tcttgtgggt agatggttct gacttaactg
     6181 actattttga agacggtgag attgatcgct tgtatctgaa cttttcagat ccatggccga
     6241 aaaaacgcca tgaaaagcgt cgtttgacct acaagacctt cttggatacc ttcaaacgta
     6301 tcttgcctga aaatggagaa attcatttca agacggataa ccgtggcttg tttgagtaca
     6361 gtttagtgag cttttctcaa tatggcatga aactcaatgg tgtctggtta gatttgcatg
     6421 ccagtgattt tgaaggcaat gtcatgacag aatacgagca aaaattctca aacaaggggc
     6481 aagttatcta ccgagttgag gcagaatttt aagagatagc ctaaaattag gctgtacaag
     6541 tgcttttgct ttacataagt tggcaaacgt gctatactga tagtaagaat atgaaaagtg
     6601 aggcggggaa atatcttcgc ctcttgctta tgaggaggtg gacgcaatcg caacaatcgt
     6661 agaattagtc agagaagttg tagaacctgt catagaagct ccttttgaac tcgtggatat
     6721 cgagtatgga aagattggca gtgacatgat tctcagtatt tttgtagata aacccgaagg
     6781 aattaccttg aacgacacgg cagacttgac agaaattatc agtcctgtcc tagacaccat
     6841 caagccagat cccttcccag aacaatattt cctagaaatt accagtccag gtttggaacg
     6901 ccctttgaaa accaaggatg ccgtcgctgg agcggttgga aaatacatcc atgtcgggct
     6961 ctaccaagcc atcgataagc aaaaggtctt tgaaggaacc ttgttggcct tcgaagagga
     7021 cgagttgact atggaatata tggacaagac gcgtaagaaa accgtccaaa ttccatacag
     7081 tttagtatca aaagcacgtt tagcagttaa attatagaaa aagaaaggat agcttttgag
     7141 gattcaaaag tgaagaaaac atgagtaaag aaatgctaga ggccttccgc attttggaag
     7201 aagacaaggg aatcaaaaaa gaagatatca tcgacgcagt agtagagtcg cttcgttccg
     7261 cttatcgcag acgctatggt cagtcagaca gcgtagctat tgacttcaac gaaaaaacag
     7321 gtgactttac agtttatact gtccgtgaag ttgttgatga agtatttgat agccgtttgg
     7381 aaatcagctt gaaagatgct cttgccatta attcagctta tgaacttgga gacaaaatca
     7441 agtttgaaga agcaccagct gagtttggtc gtgtagcagc ccagtctgcc aaacaaacca
     7501 tcatggaaaa aatgcgcaag caaacacgtg ccatcactta caatacttac aaagaacatg
     7561 agcaagaaat catgtctggt acagtagaac gctttgacaa ccgctttatc tatgtcaacc
     7621 ttggtagcat cgaagcccaa ttgtcaaaac aagaccaaat tcctggagaa gtttttgctt
     7681 ctcatgatcg tatcgaagtt tatgtttaca aggttgaaga caaccctcgt ggtgtgaacg
     7741 tctttgttag ccgtagtcat ccagaaatga tcaaacgttt aatggagcaa gaaattccag
     7801 aagtttatga tggaactgtt gaaatcatga gcgtggctcg tgaagcaggt gaccgtacga
     7861 aggttgctgt tcgtagccac aatccaaacg tggatgctat cggtacaatc gttggacgtg
     7921 gtggtgctaa tatcaagaag attactagca aattccaccc agctcgttac gatgctaaaa
     7981 atgaccgcat ggtaccaatc gaagaaaata tcgatgttat cgagtgggta gcagatccag
     8041 ctgaatttat ctacaatgcc atcgctcctg ctgaggttga ccaagttatc tttgatgaaa
     8101 acgacagcaa acgtgccttg gtggttgttc cagataacaa gctttctctt gccattggtc
     8161 gtcgtggaca aaacgtgcgc ttggcggctc acttgactgg ttaccgtatc gatatcaagt
     8221 ctgctagcga atttgaagcc atggaagacg ctgcttcagt agagttggaa gtagaaaacg
     8281 atactgtaga agaataaaag ctgctagagg agggaaagat gaaaacaaga aaaatccctt
     8341 tgcgcaagtc tgttgtgtct aacgaagtga ttgataagcg tgatttgctc cgcattgtca
     8401 agaacaagga aggacaagtc tttattgatc ctacgggcaa ggccaatggc cgcggcgctt
     8461 atatcaaact agacaatgca gaagccctag aggcgaaaaa gaagaaggtc tttaaccgca
     8521 gctttagcat ggaagtggaa gaaagctttt atgacgagtt gatcgcttat gtggatcaca
     8581 aagtgaaaag aagagagttg ggacttgaat aagcaaaaga taagtaatct cttggggctt
     8641 gctcagcgag cagggcgcat catatcgggt gaagaattgg tggtcaaggc cattcaagac
     8701 ggcaaggcca agttggtctt tctagctcat gatgctggac ccaatctgac caagaagatt
     8761 caagataaaa gtcattatta tcaagtagaa attgtaaccg tgttttcaac actggaatta
     8821 agcatagcag tcgggaaatc gagaaaggtt ttggctgtaa cagatgctgg atttacaaag
     8881 aaaatgaggt ctcttatgga atagaagagg aggacatgat ttgtctaaga aaagattgta
     8941 cgaaatcgca aaagaacttg gaaaagaaag taaagaagtt gtagcgcgtg caaaagagtt
     9001 gggcttggat gtgaaaagcc actcatcaag tgtggaagaa gctgtcgctg caaaaattgc
     9061 tgccagcttt aagcctgcag ctgctccgaa agtagaagca aaacctgcag caccaaaagt
     9121 aagtgcagaa aagaaagccg aaaaatctga gccagctaaa ccagctgtag ctaaggaaga
     9181 ggcaaaaccg gctgagccag ttgctccgaa aacagaaaaa gtagcagtga aaccgcaaag
     9241 tcgtaatttc aaggctgagc gtgaagcccg tgctaaagag caggcagaac gacgcaagca
     9301 aaataagggc aataaccgtg accaacaaca aaacggaaac cgtcagaaaa acgacggccg
     9361 taatggtgga aaacaaggtc aaagcaaccg cgacaatcgt cgctttaatg accaagctaa
     9421 gaagcagcaa ggtcagcaaa aacgtagaaa tgagcgccgt cagcaagagg ataaacgttc
     9481 aaatcaagcg gctccacgta ttgactttaa agcccgtgca gcagccctaa aagcagagca
     9541 aaatgcagag tacgctcgtt caagtgagga acgcttcaag cagtatcagg ctgctaaaga
     9601 agccttggct caagctaaca aacgcaagga accagaggaa atctttgaag aagcggctaa
     9661 gttagctgaa caagcacagc aagttcaagc agtggttgaa gtcgtccctg agaaaaaaga
     9721 acctgcagtg gatacacgtc gtaaaaaaca agctcgacca gacaaaaatc gtgacgatta
     9781 tgatcatgaa gaagatggtc ctagaaaaca acaaaagaat cgaagtagtc aaaatcaagt
     9841 gagaaatcaa aagaatagta actggaataa caacaaaaag aacaaaaaag gcaataacaa
     9901 gaacaaccgt aatcagactc caaaacctgt tacggagcgt aaattccatg aattgccaac
     9961 agaatttgaa tatacagatg gtatgaccgt tgcggaaatc gcaaaacgta tcaaacgtga
    10021 accagctgaa attgttaaga aacttttcat gatgggtgtc atggccacac aaaaccaatc
    10081 cttggatggg gaaacaattg aactcctcat ggtggattac ggtatcgaag ccaaacaaaa
    10141 ggttgaagtg gataatgctg acatcgaacg tttctttgtc gaagatggtt atctcaatga
    10201 agatgaattg gttgagcgtc caccagttgt tactatcatg ggacacgttg accacggtaa
    10261 aacaaccctt ttggatactc ttcgtaactc acgtgttgcg acaggtgaag caggtggtat
    10321 tactcagcat atcggtgcct accaaatcgt ggaaaatggt aagaagatta ccttccttga
    10381 tacaccagga cacgcggcct ttacatcaat gcgtgcgcgt ggtgcttctg ttaccgatat
    10441 tacgatcttg gtcgtagcgg cagatgacgg ggttatgcct cagactattg aagccatcaa
    10501 ccactcaaaa gcagctaacg ttccaatcat cgtagctatt aacaagattg ataaaccagg
    10561 tgctaaccca gaacgcgtta tcggtgaatt ggcagagcat ggtgtgatgt caaccgcttg
    10621 gggtggagat tctgaatttg ttgaaatctc agctaaattc aaccaaaata tcgaagaatt
    10681 gttggaaaca gtccttcttg tagctgaaat ccaagaactc aaggcagacc caacagtgcg
    10741 tgcaatcggt acggttatcg aagcgcgctt ggataaagga aaaggtgcgg tcgcaaccct
    10801 tcttgtacaa caaggtacct tgaatgttca agatccaatc gttgtcggaa ataccttcgg
    10861 tcgtgtccgt gctatgacca acgaccttgg tcgtcgtgtt aaagttgctg gaccatcaac
    10921 accagtctct atcacaggtt tgaacgaagc accgatggcg ggtgaccact ttgccgttta
    10981 cgaggatgaa aaatctgcgc gtgcagcagg tgaagagcgt gccaaacgtg ccctcatgaa
    11041 acaacgtcaa gctacccaac gtgttagcct tgaaaacctc tttgataccc ttaaagctgg
    11101 ggaactcaaa tctgttaatg ttatcatcaa ggctgatgta caaggttctg ttgaagccct
    11161 ttctgcctca cttcaaaaga ttgacgtgga aggtgtcaaa gtgactatcg tccactcagc
    11221 ggtcggtgct atcaacgaat cagacgtgac ccttgccgaa gcttcaaatg cctttatcgt
    11281 tggtttcaac gtacgcccta caccacaagc tcgtcaacaa gcagaagctg acgatgtgga
    11341 aatccgtctt cacagcatta tctacaaggt tatcgaagag atggaagaag ctatgaaagg
    11401 gatgcttgat ccagaatttg aagaaaaagt tattggtgaa gcggttatcc gtgaaacctt
    11461 caaggtgtct aaagtgggaa ctatcggtgg atttatggtt atcaacggta aggttgcccg
    11521 tgactctaaa gtccgtgtta tccgtgatgg tgtcgttatc tatgatggcg aactcgcaag
    11581 cttgaaacac tacaaagacg acgtgaaaga agtgacaaac ggtcgtgaag gtggattgat
    11641 gatcgacggc tacaatgata ttaagatgga tgatgtgatt gaggcgtatg tcatggaaga
    11701 aatcaagaga taagattttt tgctcctttc ttaggtggtg agggacgcaa gcaaaccgat
    11761 ggtttcattg cttatttttg agcctagggt ctcaaaaatc ccctgtgatg ggactgataa
    11821 atcagttcca tcactttcac cacggcgaaa gaagcagatg acttcaaatt gaacttcgtt
    11881 tcaatttaaa ctgaaaatca agaagtttaa aatagctagg tctgctggcc tagcttttgg
    11941 ttcaaagtag agaaaggaat atcatggcaa atcatttccg tacagatcgt gtgggcatgg
    12001 aaatcaagcg tgaagtcaat gagattttgc aaaagaaagt ccgtgatcca cgtgtccaag
    12061 gtgtgaccat cacagatgtt cagatgctgg gtgacttgtc tgttgccaag gtttattaca
    12121 ccattttgag taaccttgct tcggataacc aaaaagccca aatcgggctt gaaaaagcaa
    12181 ctggtaccat caaacgtgaa cttggtcgca atttgaaatt gtacaaaatc ccagatttga
    12241 ccttcgtcaa agacgagtcc atcgagtatg gaaacaagat tgacgagatg ctacgcaatc
    12301 tggataagaa ctaaagaaga ggggttgccc ctcttttttg gtggaggaaa ataggttgaa
    12361 tttgaaatgg aaaaatattc ttttaaaata tattgaaact agaatagtac gc
//
LOCUS       DAVLAQ010000054        12365 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000054 DAVLAQ010000000
VERSION     DAVLAQ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.054"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(24..221)
                     /gene="blpI"
                     /locus_tag="VXB71_001631"
     CDS             complement(24..221)
                     /gene="blpI"
                     /locus_tag="VXB71_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV0451717.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            503..1090
                     /locus_tag="VXB71_001632"
     CDS             503..1090
                     /locus_tag="VXB71_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0451718.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1017..2660
                     /locus_tag="VXB71_001633"
     CDS             1017..2660
                     /locus_tag="VXB71_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0451719.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2671..4032
                     /locus_tag="VXB71_001634"
     CDS             2671..4032
                     /locus_tag="VXB71_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0451720.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4089..4217
                     /gene="blpC"
                     /locus_tag="VXB71_001635"
     CDS             4089..4217
                     /gene="blpC"
                     /locus_tag="VXB71_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0451721.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4288..5628)
                     /locus_tag="VXB71_001636"
     CDS             complement(4288..5628)
                     /locus_tag="VXB71_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0451722.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5642..6379)
                     /locus_tag="VXB71_001637"
     CDS             complement(5642..6379)
                     /locus_tag="VXB71_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0451723.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6384..6722)
                     /locus_tag="VXB71_001638"
     CDS             complement(6384..6722)
                     /locus_tag="VXB71_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0451724.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6999..7328
                     /locus_tag="VXB71_001639"
     CDS             6999..7328
                     /locus_tag="VXB71_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0451725.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7496..8545)
                     /locus_tag="VXB71_001640"
     CDS             complement(7496..8545)
                     /locus_tag="VXB71_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451726.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8542..9273)
                     /locus_tag="VXB71_001641"
     CDS             complement(8542..9273)
                     /locus_tag="VXB71_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451727.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9341..9751
                     /locus_tag="VXB71_001642"
     CDS             9341..9751
                     /locus_tag="VXB71_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0451728.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9761..10048
                     /locus_tag="VXB71_001643"
     CDS             9761..10048
                     /locus_tag="VXB71_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451729.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10210..10494
                     /locus_tag="VXB71_001644"
     CDS             10210..10494
                     /locus_tag="VXB71_001644"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451730.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10806..11942)
                     /gene="dnaJ"
                     /locus_tag="VXB71_001645"
     CDS             complement(10806..11942)
                     /gene="dnaJ"
                     /locus_tag="VXB71_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0451731.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
BASE COUNT         3989 a         2665 c         2185 g         3526 t
ORIGIN      
        1 tactatattt aagaatcata atcttacaaa gaggacataa ttcctgaacc tacacaaata
       61 agtgttgctg ctcccccagt tatcggacca gtcgcagcag ctaatagtac tgctccaata
      121 caaccaccga ttgcagatcc taaattgcct cttcctccac taactatttc gagttcttca
      181 ttatccataa cagaaaattg ttccatcatt tttgtattca tgacaaatac tccttttttc
      241 tttttttatt tttgtcttgt tgtaactttg ataagtttag tatatcatcg ttttttaaaa
      301 tttttcatcc agatcttgaa ttgtcatcga aacgtcttga attaggtttt ttatttcaag
      361 ccacctctaa atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt
      421 taatgactat tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc
      481 cactatatga aaggaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga
      541 tgcgagagac tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt
      601 ttctctagct cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg
      661 cattgtaaaa gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac
      721 gctctttgac atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa
      781 actccaacat tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc
      841 tgacccttct gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg
      901 agtagctatt tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg
      961 tctactaagc aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg
     1021 ttctctcaag cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa
     1081 tcttggatga atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc
     1141 tggttatcac ctatatcctc caacaagtca tgagcttctc cagagattat ctcctaaccg
     1201 ttctgagtca gagattaagt attgatgtga ttttatccta tattcgccat atttttgaac
     1261 ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacga ttcacagatg
     1321 ctaactctat tatagatgcc ttggcttcta ccattctttc tctttttctg gatgtttcta
     1381 ttctgattct tgtaggaggc gtcttactgg cacaaaaccc taatctcttc cttctttctc
     1441 ttatttccat tcctatatac atgttcatca tcttttcttt tatgaaacct ttcgaaaaaa
     1501 tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc gaagatatca
     1561 acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa aatatagaca
     1621 gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct attttacaaa
     1681 cgagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg tttggcgctc
     1741 aattagtcat gtcgagtaaa atttctatcg gtcagctgat tacctttaac acactttttt
     1801 cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc caatctgcga
     1861 aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt caagttcaag
     1921 aaaaccctgt ccattcacat tttttgatgg gcgatattga atttgatgac ctttcttata
     1981 agtatggttt tggacgagat accttaacag atattaatct cacgattaaa caaggagata
     2041 aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa atgattgtca
     2101 atttctttga accctacaaa ggacatattt ctatcaatca tcaggatatt aaaaacattg
     2161 ataaaaaagt cttgcgccgt catattaatt acctaccaca acaagcctat atctttaatg
     2221 gctctatctt ggaaaactta actttgggcg gtaatcatat gattagccaa gaagatattc
     2281 taagagcttg tgaattagct gaaattcgtc aagacattga aagaatgcct atgggctatc
     2341 aaactcagct ctctgatgga gctggtctat caggaggaca aaagcaacga atagccctcg
     2401 ctcgtgctct tttaactaaa gctcctgttt taatactaga cgaagctact agcggtcttg
     2461 atgtcttgac tgagaaaaag gttatagata atcttatgtc tctaactgat aaaaccattc
     2521 tctttgtagc ccatcgtctc agtatagccg aacgaaccaa ccgtgtcatt gttcttgacc
     2581 aggggaaaat cattgaagtt ggtagtcacc aagagttaat gcaggcgcaa ggtttctacc
     2641 atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag aagcgtcgag
     2701 ttttatcaga gacgttacca taactatgcg acagtgttca ttatacctct ttcattacta
     2761 tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt tacttcccaa
     2821 ggagaaatcg cccctacaag tgtcattgcc tccattcagt caaccagtga taatcctatc
     2881 ctagctaatc atttagtggc aaatcaagta gttgaaaaag gggacttact catcaaatac
     2941 tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca aagacttgag
     3001 aagcaaaaag aaggacttgg aattttgaaa caaagcttag aaaaagcgac tgatcttttt
     3061 tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa acaatcccat
     3121 gatattgaac tgggtatcac aaagactaac accgaagttt caaatcaagc taatctttcc
     3181 aatagcagtt catcagctat tgaacaagaa attacaaaag ttcaacaaca aattggagaa
     3241 tatcaagagt tgagagatgc tatcataaat aacagagcac gcttaccaac tggcaatccg
     3301 caccagtcaa ttttgaatcg ttatcttgta gcctcacaag gacaaacaca aggaactgca
     3361 gaggagccat ttttatctca aattaatcaa agtattgcag gtcttgaatc atctatcgca
     3421 agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa cagtttagca
     3481 accaaaattg aagtactccg cactcagttt ttacagacag cctcacagca acaactaact
     3541 gtggagaatc aattaacaga attaaaagta caactagatc aagccacaca gcgtttggaa
     3601 aacaatacct taacctcccc aagtaaaggt atcgttcatc tgaacagcga atttgaaggt
     3661 aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctgtcat cacagataca
     3721 agagaagtac taatcactta ctacgtatct tctgactatc tacctctact agataaagga
     3781 caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcaccaccat catcggccaa
     3841 cttcagacaa ttgatcaaac tcctaccaga acagagcaag gaaatctctt taaattaacc
     3901 gctcttgcaa aactatctaa cgaggatagt aaactcatcc aatatggctt acaaggtcgc
     3961 gtcactagtg taactacaaa gaaaacatat tttgattatt tcaaagataa aattttaacc
     4021 cattctgatt aattttcaga taacactcta taactattta ttatcttatc aaaaaggaga
     4081 atcataacat ggataagaaa caaaacctaa cttcatttca agaactaaca actaccgaac
     4141 tcaaccaaat tacaggtgga ggattgtggg aagatttatt atataacatt aatagatatg
     4201 ctcattacat cacataagaa cttcatcatc caatacaact ataaaaaaat aagaccgaga
     4261 aacaagtact ctcggtctta tttttcatca ttctgtatgt atcacagtaa gtacctgacg
     4321 aaagacttga ttttgacagg tggtatttag actggtatta ggatggcttt ccacaatctt
     4381 catgacggta tagagaccaa ctcctctctc ctccccttta gaactggctc caaaggagaa
     4441 gatttcagaa atatcgatgc cctcttcttt gatggagttt tcgatgataa aggtctcctg
     4501 tgctccattt tttaaaaagg cgattgaaac atgaggttga ctagcttcca cactggcttc
     4561 aatagcattg tcacaaagga tagacacaat ggttagaaaa tcaagtagac tcatcccctc
     4621 gacctgaatc tcctcaggaa cttcgacatt aaagacaatg ttcttatctc tggcttttaa
     4681 aaatttccct gctagaagac ttttgagggc tttatcacga atatttacca atctgcccag
     4741 gtcatattta ttgttctgca atttctgact ggaatccttt aagacggagc catagacctc
     4801 ttttatctgc tccatatcct cctcttcaat gcccagacgt aagctagtca agaggttggt
     4861 ataatcatga cgaaagctcc gtacttcctt gtaaagctcc tctatatgcc gactatagcg
     4921 ttccatatct ctatagcgca gggcctgctc ttgttccaat ctctcataga gtttttcctt
     4981 caaataggta tccaatttct tgataacccc cataaaaaag agtaggtaaa agactaggat
     5041 gagatggcga acagtctttg attgaatact ttgttcatat tcaaaaaaag acagactttc
     5101 catgactaga tagtagccac ccattatcca gttaatctga gtcagggact tttgaaaggc
     5161 tttatcgaga atctcctttc tcaagctagt aaaatcgtag tccaaccatt tcaaaaaagc
     5221 tagagaaatg aagaaattga aaattattat acataaccca gtaaatgagt agccatcata
     5281 tacttgccct tgtcccaaaa atggaagcac aaaataggag actcctctat aaaagagatt
     5341 caccaatatc attggaaaga gaccataaaa gaaaaggagt tttttaggaa gccctctcaa
     5401 taataagaaa gataagccta tgccgtacaa gggttccata aaataagata ggtaaacatt
     5461 tcctactata tagctaatca tcacaaaaac aaaggccaac agtatcttaa aaagaaaggc
     5521 cttaaaaatc ctctcgaaag taagatcaat tccatccacc ttaaagaaga tgacaatttc
     5581 tagtccatta gtaacaagtg tatacaacaa tatccaagca atgttcataa attctcctag
     5641 ctcagtgtaa tttattgatg gcctcagaca cttccctgac cttataacgg gcgattagac
     5701 aacttccacc attgggaaag aaaagcagtt tttctttctt atccaaatgc accacatttg
     5761 caggattgat gagaaaagag cggtggcact gcaagagacg gggctcctgc ttgaaaacct
     5821 cctctaaact cgctgtaaat tccagcctgt ctgtcttggt atagagaata acacgatggg
     5881 ctctgggcga cgtttcgaga tagtaaacct ctttaaaagg atactgaaat tgggcaaatt
     5941 ttgatttaaa gtaaaagcaa tcttccgcca gacttttact atcttgacta ttggcataga
     6001 ggagggctgt ctcgatccga gattcaaact cctctgctga caaggcctta tcaatgtagt
     6061 ccaaagcaga cacttggtag cgaaaagaca ggggcataaa ctccgagtga gtcgtcacaa
     6121 agacaatcag ggcataagga tcccgatccc gaatctttct agccacttcc agtcccttca
     6181 tctcttcatt tcgaatctca atatccaaaa agaatagctg atgggccccc ttctcatgca
     6241 cttcagccag cagttggtcc ggcttgccaa atacctcaaa agagctagga atgatatgat
     6301 gtgctttcaa aagtttctca atcgtcgttt caattctagt ctgttgggaa aaatcatcct
     6361 ctaaaacaaa tattctcatc ttcttactct ccctctttca accatttttg acgaatttct
     6421 ctatagcgac gtctggcata cttgacagcg tattgacctt cttctccgag aaaaaggatt
     6481 ctttcttgaa aatcaatcga ttttaattta tcaagattaa ccaaacaatt tcgatgacat
     6541 ctcatcaagg tttccccaca ttggttctca agattactta aattttgaag catattaaaa
     6601 ctagcttctt ctgtaacaat ctgtacggta tgggctttag ttggatgtgt ttggatatag
     6661 tagatatcgt cgatgtttac tttatagact gttttctgcg tctgaataat catatatttc
     6721 attggattct cctcctaaga aaagaataac agaaaaggtc tagcccaagc acacccaatc
     6781 ctaaacagtc tttgaaaact cctaaaagga ttattttcta caacatcatg atgagcttac
     6841 aactatttta tcataaaatt cactcagcgc aattcaagac atttcaatga caattaaaga
     6901 tttgaataaa aaaaaaagaa ttaaaagtga taaactaaca gtatcaaaac acagttgcca
     6961 gaagtaagac tggcacccag attaaaggag gcattcccat gacagataca gaccccatca
     7021 aaagagctca tactttgatt actgacttaa acaaagccta ccaagcatgc aaacaggcaa
     7081 gcgctgacga cgtccgcttt caggagcaat taaactctat tcttggtttt ctagccaagg
     7141 ctgaaacagt ggataatcga ttcttgattg aactagaaaa attttaccag acttccagtc
     7201 ttctcatggg actcagcgct cttgatccag atgctccaac tcgcgccgct tggcgggcct
     7261 atgaccgctt ccactttgac caagtcaaga ccaagttaat actcaatgaa aatcaaagag
     7321 caaactagga agctagccgc aagctgtact tgagtacggt aagacgacgc tgacgtggtt
     7381 tgaagagatt ttcgaagagt ataagtctct acggaccaac cattatcctg tagtaacaaa
     7441 aaagaagttg agacagactg aactcaactt cttttttagt gtcgtatcag caatgttagt
     7501 cctgcatctg acgttttacc tgataaggca aatacaagac tagtaaaacc aaaccagctc
     7561 ctagtaaggc tagaagggct agtttttctt ggaaggtaat caacccaaca actaattcca
     7621 caagtaaaac aaaactggtc aatcctcgaa ctacctcctg taagcctttt tccttttgcc
     7681 ccttgtccag cggaaagagt tgggtcaaat actggtagtc aaaggcatga tagagggcca
     7741 gcaactggaa gagcaagagg tagttaaaga gaactaccac tgctgtcgca atccaagctt
     7801 gctcgataaa aacctgcgcc agtacggaaa gtaagagaag acgaagactg agagcaaaga
     7861 ggtcgccatt tcgcagataa gaacgcagat agagattttg ccaaatcttt ccagacacct
     7921 tctgaacagc ctttaagata aagtccagat aggcacgacg tttgacactg tttgaaattc
     7981 cctttacctg cgtaaagagg gcaaagaaac gaagcaagac ttgcttacgc ttgctttctt
     8041 gggaaatgac atagtcccag tccagcccag tttcagtgaa aaatttgctg gccttttgac
     8101 gaaagtggaa atattttcct acccccaata aaagcacata gagcagaaaa actggcaagc
     8161 cataacccat tgctaaaaat aaaggcgcaa ataacagcaa gaaaagggtc tgtacaaaga
     8221 gccaaaagac tagggaaatg ccagtttgac gcttgagatg gagcttgatt tcctcttctc
     8281 caactaagag aaagagcttg tctggagcct ccatataggt ggcaattcct ccccaaagta
     8341 aaagtaaaac agacgtaatt cctacaaaca aaaggatagg ccaatgattt tcaggaaaat
     8401 gttgtaagag ttgactgtac tggtaggcta gaaagcccaa caggacaagc aggaacaaga
     8461 caaagtggtc attgagcaca tagcgcagat aaccaaggca ctccttacga aaggcctgct
     8521 ttctctttaa aaacaagtct ttcatagatc ctcctctttg gtcagagcca agtaaatatc
     8581 attcaaacta gcctcaggca tatcaaaggc ttcacgtagt tgcaggagat tgcctttggc
     8641 acgcacctct cccttgtgaa gaatgacaaa ggcatcacac atcttctccg ccgaatccag
     8701 cacgtgggta ctcatgagaa tagacttgcc cttttgcttc tccacttcca aaagctgaat
     8761 caaatcagaa atagccagcg gatcaagacc aaggaaaggc tcatccacga tgaaaagact
     8821 tggatccacc acaaaagcac agataatcat gaccttctgc ttcatccctt ttgaaaaatg
     8881 aacagggaac cagtctaatt tctgttccaa acggaacatt tttaacaagg gctctactcg
     8941 ttcgaaagcc actttttgct caataccgta agccatagca accgtttcga tatgctctct
     9001 gagggtcaat tcctcataca gactaggcgt ctcaggaatg tagccaatct gcttgcggta
     9061 gctagtcgca tctccttgca gagtcaggcc attgatattg atggagccac tataaggtgc
     9121 caacagaccg ataatctcat tgatcgtcgt tgatttccca gcaccattga gaccaatcaa
     9181 accgaccaac tgcccacttt caacagtaaa ggacacatct ttcaaaacag ggacatgaac
     9241 atagccacct gtcaggtttt taatttctaa catattttct ccaaatctgg tataatgtag
     9301 ctatattata tcaaaattca gtacagtaga ggtagatttt atgtcagatt gcattttttg
     9361 taaaatcatc gcaggggaaa ttcctgcttc aaaagtatat gaagatgagc aggtccttgc
     9421 ctttcttgat atctctcaag taacactagg acacaccttg gtcgtgccaa aagaacacta
     9481 tcgcaatctt ttggagatgg atgctacgag cgccagccaa ctctttgccc aagtaccaaa
     9541 agtagctcaa aaagtcatga aagtcactaa ggctgctggt atgaatatca tttccaactg
     9601 tgaagaagtc gctggtcaaa cagtttttca tactcacgtt caccttgtac ctcgctacag
     9661 tgctgacgat gacctcaaga ttgattttat cgcccacgaa ccagactttg acaaacttgc
     9721 tcaagtcgct gaaaccatca aaaacgctta aggagttgct atgaaattat ccaacctact
     9781 gctatttgca ggagctgcag ccggaagtta tctggtcaca aaaaatcgcc aaaccatcac
     9841 agatgaagtc ttgaatacca ctgaccgcgt tcaagctatc aaggacgatg tggatattat
     9901 ccaaaacagc ctgcaaatca ttgaccagca aaaagaactt atcaaggaat accaagaaga
     9961 cttgacttac aagtttaagg tcttggaaaa ggatatccag actagactag ctgtgataaa
    10021 agaaatgcag ggaactgaag ataagtaaaa agagcccccc ggctcttttt taaaacgtaa
    10081 acaagttata gtgaattgaa tttagaatag cacatcatag tttctaaagc attgttagag
    10141 attactttaa aatcctctta tcaatttgtt catattctat ttcaatctac tatatatatc
    10201 ccatcaacta tgcatcataa tttaggtaac tcatactcaa taaaaatcaa aaagcaaact
    10261 agaaagctag gcacagactg ctcaaaacac cgttttaagg ttgtggatag aactgacgaa
    10321 gtcagctcaa aacactgttt tgaggttgta gatacgactg acgaagtcag ctcaaaacac
    10381 tgttttgagg ttgtggatag aactgacgaa gtcagtaacc atacccatga caagccgacg
    10441 ctgacgtggt ttgaagaaat ttttgaagag tatcattcac catttcacaa ctaaatcgaa
    10501 gactttctgc cgtaatgaaa acacctgaaa cagcttggtt tcggctgtcc ggaaacttta
    10561 agacttaggt tcaaagttta ggtatggaac ttcgaaggag gtcgctaccg tccgtcatta
    10621 cttaggaaag tcttaaaaaa tcggctctat aaagtaaaaa gagcccgaca gctctttttg
    10681 tttatattca atgaaaatca aaaagcaaac taggaaacta gccacgggct gctcaaaaca
    10741 ctgttttgag gttgtagata cgacaagccg acgctgacgt ggtttgaaga aatttttgaa
    10801 gagtattatt ctccatcaaa ggcatcttta atatggtcaa agaagccttt tttctttgga
    10861 tttactttca agtcaccagc agccgcgaat tctttcaagg ctactttttg gcggtcgttc
    10921 aagcctgtcg gtgttacgac attaacagta acgtattggt caccaactgc accgccacga
    10981 aggctcggtg cccccttact acgtaggcgg aatttcttac cagtctgagt tccctctgga
    11041 ataaccaatt caacatcacc gtgaacagtt ggaatatcta ctgtatcacc aagagccgct
    11101 tggacaaagt tgaggttgag attgtagaag atagtcgttc cttcacgttc aaacttgtcg
    11161 ctagcttcta cagaaactac tacatacaag tcaccataag gtccaccgtt aaagcctgct
    11221 tcaccttgac cagcgaggcg aatttgttga cctgtttcca caccagcagg gattttcaca
    11281 tgtacgctat gagcttgttt ctcatgacct gttccatgac aggttgtaca tggatatttg
    11341 atttcttttc ctcgaccgtg acagacatca caggttactt ggcgacgcat cataccaaga
    11401 ggagtctgcg tatcgacgtt aatgacacca gcgccatgac agcgtccaca agtgactgga
    11461 cttgtccctg gcttagcacc agagccatta catgtacgac agccagcttc acgatgatac
    11521 ttaacttcct tctcagttcc gaagatagct tcttcaaagg tcaaattgac acgatactgg
    11581 agatcatctc cttggcgagg agcgtttgga ttgcgcgaag aaccgcctcc gccgaagaaa
    11641 cttgagaaaa tatcctcaaa accaccgaaa ccacctgccc cattgaaacc gccgaaacca
    11701 ccagctccac caaaaccacc attggcgcct gcagcaccat actggtcata ggcagcacgt
    11761 ttttggtcgt cactcaaagt ctcataggct tcttgaactt ccttgtactt gtcctcagca
    11821 ccaggctcct tgttgatatc tgggtgatat tttttggaaa gcttacgata agcctttttg
    11881 atttcgtctg ccgaagcgtt tttggatacc cccagacgat cataaaattc agtattgttc
    11941 ataattcaag atacaaaggg cgtcaaacgg acacagccat ctaggagttt tgacgacgga
    12001 cgcttacgtc ctagaaaaaa ctatcttttg ggcacagtcc gtagcccgtg ttcagttacg
    12061 aacaccctta ttcctttcta ttgatgttct gaatcgaacc accatttagg tcgggttcaa
    12121 ttcctttctt ttatatttag taagaaattc tgaaacccgt gttcagttac gaacactctt
    12181 tgttcccttc tattgatgag acaaaaccca aacaaatgag attccgtccc tttttatcga
    12241 aaaacagagg ctgggttgca acctctgcaa ataagtaaat taactttatt ttgattttaa
    12301 atatcctata agtacagaaa tatttatata tttttgtctc ttcttagtat ttgcctatat
    12361 aattc
//
LOCUS       DAVLAQ010000055        11814 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000055 DAVLAQ010000000
VERSION     DAVLAQ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.055"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            112..765
                     /locus_tag="VXB71_001646"
     CDS             112..765
                     /locus_tag="VXB71_001646"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0451732.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            775..1239
                     /locus_tag="VXB71_001647"
     CDS             775..1239
                     /locus_tag="VXB71_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0451733.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1252..2520
                     /locus_tag="VXB71_001648"
     CDS             1252..2520
                     /locus_tag="VXB71_001648"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0451734.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2534..2794
                     /locus_tag="VXB71_001649"
     CDS             2534..2794
                     /locus_tag="VXB71_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451735.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2805..4166
                     /gene="pdrM"
                     /locus_tag="VXB71_001650"
     CDS             2805..4166
                     /gene="pdrM"
                     /locus_tag="VXB71_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0451736.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4320..5288
                     /locus_tag="VXB71_001651"
     CDS             4320..5288
                     /locus_tag="VXB71_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0451737.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5304..6296
                     /locus_tag="VXB71_001652"
     CDS             5304..6296
                     /locus_tag="VXB71_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0451738.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6514..7557
                     /locus_tag="VXB71_001653"
     CDS             6514..7557
                     /locus_tag="VXB71_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0451739.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7621..9306
                     /gene="lpdA"
                     /locus_tag="VXB71_001654"
     CDS             7621..9306
                     /gene="lpdA"
                     /locus_tag="VXB71_001654"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0451740.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9370..10359
                     /locus_tag="VXB71_001655"
     CDS             9370..10359
                     /locus_tag="VXB71_001655"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0451741.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10432..11502)
                     /gene="xerS"
                     /locus_tag="VXB71_001656"
     CDS             complement(10432..11502)
                     /gene="xerS"
                     /locus_tag="VXB71_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0451742.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3508 a         2206 c         2657 g         3443 t
ORIGIN      
        1 attcaaatcg tatatatagt cgatttatta aatctttaga taaactgtaa aaagtggttt
       61 ccatagccac tttttgctat aatagaggca gtaaaaatga aggagtcggc tatggaacac
      121 tcgtcttggc atgctttgat taaggcgcaa ttacctgagg gttatttcgg gaaaatcaat
      181 cagtttatgg agcaggtcta ttctcagggg attatttatc cacccaagga aaaggttttt
      241 caggctctct tgacaacact gcttgaagaa gttaaggtgg taattctagg gcaagacccc
      301 tatcacggac caggtcaagc gcagggcttg agtttttctg tacctgactc tatcccagct
      361 ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg atatcggagt taagaaatct
      421 catgatttga cagcttgggc tgagcaagga gtcttgcttc ttaatgcttg tttgactgtt
      481 cctgctggac aggccaatgg tcatgctggt caaatctggg agccttttac tgatgctgtg
      541 attcaggtgg tcaatcatct agatagacca gtcgtttttg tactctgggg agcttatgca
      601 cgtaagaaga aggcattagt taccaatcct catcacttga ttatcgaatc agcccatcca
      661 agtcctttgt cggtttatag aggattttgg ggttccaagc ccttttccaa ggccaatgca
      721 ttcttaaaag agacaggaca agagccaatc gattggctta gataaggaga aaatatgcct
      781 cagttagcga cgatttgcta cattgataat gggaaagaac tgctcatgct ccatcgtaat
      841 aagaaaccca atgatgtcca tgaagggaaa tggattggtg tgggtggtaa gctagagaga
      901 ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg aagaaacagg gctcaaagcc
      961 aagccagttc taaaaggtgt catcactttt cctgaattta caccagattt agactggtac
     1021 acctatgttt ttaaggtgac ggagtttgag ggcgacttga ttgactgcaa tgaggggacg
     1081 ctagaatggg ttccctatga tgaggttttg agcaagccga cttgggaagg tgaccacacc
     1141 tttgttgagt ggcttttaga ggataaaccc ttcttttcag ccaagtttgt ttatgatggg
     1201 gataaattgt tggataccca agttgatttc tatgaataaa ggagaaagca gatgctacta
     1261 atcaaaaatg gtcgtgtaat ggatcccaag tctggtttgg atcaagtttg tgatgtctta
     1321 gttcaagatg ggaaaattat caaaattgcg cctgagatca cggaagaagg agcagaaacg
     1381 attgatgcta ctggtcttgt ggttgctcct ggtttggtcg atattcatgt gcatttccgt
     1441 gaacctggtc aaacacataa agaagacatt catactggtg ccctggcagc cgctgcaggt
     1501 ggttttacta ctgtcgtcat gatggctaat accagtccaa ccatttcaga cgtggagact
     1561 ttgcaagcag ttctccagtc agctgccaaa gagaagatta atgtcaagac agttgcgacc
     1621 attactaaaa actttaatgg taaaaacttg actgacttta aggcgctctt agaagctggt
     1681 gcggctggtt tctctgatga cggtattccg cttgagagca gtaagattgt caaggaagcc
     1741 atggaggaag ccaaaaaatt caataccttt atcagccttc atgaggaaga tccaggtttg
     1801 aacggtgttc ttggctttaa tgaaaatatt gctagagaac atttccatat ctgcggtgct
     1861 actggagtgg ctgagtacgc tatgatggcg cgtgatgtca tgattgccta tgcaactaaa
     1921 gcccatgttc acatccagca tttgtctaag gaagaaagtg ttaaagtagt ggagtttgct
     1981 caggggttag gtgcagaagt cacagcagaa gtagcgccac agcatttctc taagacagaa
     2041 gcacttcttt taacacaagg tagcaatgct aagatgaatc caccgcttcg tttggaatca
     2101 gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca tcacagttat tgcgactgac
     2161 cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata ttaccaaagc gccatctggt
     2221 atgactggct tagaaacatc cctgtctctc agcttgacct atttagtaga agctggtgag
     2281 ttgagcttga tggaattact tgaaaaaatg acatacaacc cagccaagct ttacaacttt
     2341 gaagcaggtt acttggctga gaatggtcca gcagatatca ctatttttga tgccaaggct
     2401 gaccgctttg tggactccca ttttgcttcc aaagcagcta attcaccatt catcggtgaa
     2461 accttaaaag ggcaggttaa atataccatc tgtaagggac aaatcgtcta tcaagcttga
     2521 taggagttag aatatgaatt attttcgaaa acgtagggag agacaagcga aatctaatag
     2581 tggaatttac tgtcccgcag ctaatcgttc caaaattcaa tatgaaacta aagaaaaagc
     2641 tgaccatgcg gttcaatatg ataacggagg tttagttaga agctattatt gtcgtacatg
     2701 tgcgtgttgg catactactt caaaatctaa taaacctccg ctaagtttga aaaactatgg
     2761 tctgaaactc tttggtttag ataaatcaga atagaaagag aagtatgtat aagacaaagt
     2821 gtttacgaga gaagttagta ttatttttaa aaattttctt cccaatcctg atctaccaat
     2881 ttgccaatta ttctgcctct tttgttgata ctgcaatgac aggtcaatac aacactatgg
     2941 acttggctgg tgtatctatg gcaaccagta tctggaatcc tttctttaca tttctaacag
     3001 ggattgtgtc agccttggtg cctatcattg gtcaccatct tggtcgaggc aaaaaggaag
     3061 aagttgcgtc tgatttttac caatttattt atttggcctt gggcctatct gtggtcttgc
     3121 tggggatggt acttttcttg gcaccaataa tcttgaatca tattgggtta gaagcagcag
     3181 tagcggcagt agcggttcgc tatctttggt ttttatctat cgggattatc cccttgttgc
     3241 tctttagcgt cattcgttcc ttgctggatt cgctgggctt gaccaaactg tccatgtacc
     3301 tcatgctttt gttactccct ctcaatagcg gatttaacta tctcttgatt tacggtgcct
     3361 ttggtgttcc agaactggga ggggctggtg ctggtttagg aacatccttg gcctactggg
     3421 tcttgcttgg gatttctgtt ctggttttat ttaaacagga gaagctcaaa gccttacacc
     3481 ttgagaaacg aattccactt aatatggata acattaagga aggagttcgt ttaggtctgc
     3541 ctattggggg aactgtcttc gcggaagtgg ctatcttttc agtggttggc ttgattatgg
     3601 ctaagttttc gtccttgatt atagctagtc accagtcagc tatgaacttt tcaagtctta
     3661 tgtacgcctt tcctatgagt atctcatcgg ctatggctat tgtcgtttcc tatgaagtgg
     3721 gagccaagcg atttgatgat gcgaaaacct atattggtct aggaagatgg actgctctca
     3781 tttttgcggc cttcacctta accttccttt acatttttag gggaaatgtg gccagtcttt
     3841 atggtaacga cccaaaattt atcgatttga cagtgcgttt tttaacttat agtcttttct
     3901 tccagttagc agataccttt gcggcgccgc ttcagggaat tttgcggggg tataaggata
     3961 cagttattcc tttttacctt ggtttgcttg gttattgggg cgtagcaatc cctgtggcta
     4021 cgctatttga ttccctaaca gattttggag cttattctta ctggatcggc ttgattatta
     4081 gtttgattgt gagcggggcg ctctaccgtt ggcgtttaac tgtgattatg aagagatttg
     4141 aatctttagc aaaatccaaa tgctaaaaag tttgtgaaaa aatattcttg acaagaaaat
     4201 cccttgtttt cacggggttt tcttttttat tttgtgaaat ttcttttaga aaaactttga
     4261 cagtatttgc caaaagcggt aaaatagtaa ggtaagaaga aagttagaaa ggcaagaaga
     4321 tgtcaacttt agataaaaat cttttgctag aaatgttccg taagatggaa gaaatccgtc
     4381 gcatggactt aaaaattgca caattagtaa agaaagggaa agtgccagga atgacgcact
     4441 tttctgttgg tgaagaggca gctaacgtgg gggctatgtt agctctcaat ccagatgatc
     4501 tgattacctc aaaccaccgt ggacacgggc aagctattgc taaagggatt gacctcaacg
     4561 gaatgatggc tgaaatcctt ggtaaataca ctggaacctg taaagggaaa ggtggatcta
     4621 tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa tggtatcgta ggtggtggta
     4681 tggggatcgc tgtcggtgca gccctcagtc agcaaatgca aaataccggt aaaatcgttg
     4741 tctgcttctt tggagatggt gcgaccaatg aaggtgtttt ccacgaagca gtgaacatgg
     4801 cttctatctg gaacctgcca gtcattttct attgcattaa caacggttac ggtatctctg
     4861 cggatatcaa gaaaatgacc aatatagaac atatccatca acgtagcgcc gcttatggaa
     4921 ttcctggaat gttcatcgaa gacggtaaca atgtcatcga tgtctatgaa ggatttcaga
     4981 aagctgtgga ccatgttcgc agtggcaatg gtccagtctt gattgaaagt gtaacttatc
     5041 gctggctcgg tcactcatca tctgaccctg gtaaatatcg tacgcgtgaa gaagtggaat
     5101 tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta ccttattgaa aataacattg
     5161 caagtgccga agaattggaa gaaatccaag cgcaagtaaa ggaagcagta gaagcttctg
     5221 ttaaatttgc agaggaaagc ccattcccac cgcttgaatc agcctttgaa gatatttacg
     5281 cagactaagg agaaagagat aaaatggaaa caaaaacaat gtccttccgt gacaccatta
     5341 tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt gttcttgatg ggagaagacg
     5401 tcggtgtctt cggaggagac ttcggtactt ctgttggaat gcttgaagaa tttggtccag
     5461 aacgtgtccg tgactgtccg atttctgaag ctgccatctc tggagcagca gcaggagcag
     5521 ccatgacagg acttcgtcca atcgtcgata tgaccttcat ggacttctct gttattgcca
     5581 tggacaatat cgtcaaccaa gctgctaaaa cacgttacat gtttggtggt aaaggtcagg
     5641 ttccaatgac tgttcgttgt gcagctggta acggagttgg ctctgccgcc cagcactcac
     5701 aatctctaga gtcttggttt actcacattc caggacttaa ggttgtggca cctggaacac
     5761 ctgcggacat gaaaggcctg cttaagtctt ctatccgtga taacaactca gttattatac
     5821 ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc agttgatcca gactacacaa
     5881 ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga tgtaacagtt gttacttatg
     5941 gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt agcagaagaa ggaatttcag
     6001 ttgaaattgt tgacccacgt acccttgttc cgcttgataa ggatatcatc ataaactcag
     6061 tgaagaaaac tggtaaggtt gttctggtca acgatgccca caaaacaagc ggctatatcg
     6121 gtgaaatttc agctattatt tcagaatcag aagcatttga ctatctagat gcaccaatcc
     6181 gccgttgtgc aggagaagat gtgccgatgc cttatgcaca aaacctagaa aatgcaatga
     6241 ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac ttataacaaa gaatagggtt
     6301 acataagata agttatgtaa ataaaataaa gctgacgaga aactttgtat cttttaggtg
     6361 cagagctctt cgtcattaat atcttagatt agagcacggg ctaaaagatc ggaaaaaaga
     6421 taaatctcct tggcttcatc gaagccatcg tcgatttcct atttttcagt cgcttttgac
     6481 gccctttgta tcataaatag aattggagag gtcatggctg atgacaagct aagagcgact
     6541 cctgcagcta gaaagttagc ggatgattta gggataaacc tctacgacgt ttctggctca
     6601 ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt ataaagacac aaacgtggtt
     6661 cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata acattgcttg gcaggaaatc
     6721 caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg ttttggccct gcttcctgaa
     6781 aatatcgaaa acgatagcat caaatctcct gctcagattg aaaaagtgga agaagtccct
     6841 gataacgtaa caccatatgg taaaatcgag cgtattccaa tgacaccaat gcgtaaggtt
     6901 attgcccaac gcatggttga atcttacttg actgcgccaa ccttcaccct caactatgaa
     6961 gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc ttgagccaat catggaagca
     7021 actgggaaga agactactgt aacagacctt ctttcgcttg cagttgttaa gactcttatg
     7081 aaacacccat acatcaacgc ttcattgaca gaagatggca agactattat cactcacaac
     7141 tatgtcaatc ttgccatggc agttgggatg gataatggat tgatgacacc tgttgtttac
     7201 aatgctgaga agatgagtct ttcagaactg gttgtagcct ttaaggatgt tattggccgt
     7261 accttggatg gtaaattggc tccaagtgag ttacaaaatt caacattcac aatcagtaat
     7321 ttgggaatgt ttggtgttca gtcctttggt ccgattatta accaacccaa ctcagctatc
     7381 cttggtgtca gttcgacaat cgagaagcca gttgtcgtca atggtgaaat tgtgattcgc
     7441 ccaatcatga gtttaggatt aaccattgac caccgtgtcg tagatggtat ggctggtgct
     7501 aagtttatga aggacttgaa agagttgatt gaaacgccaa tctcaatgtt aatttaagag
     7561 caagagtatt catttttaag atatagataa aggaaggaag acatggcctt agaagtaatt
     7621 atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg tccaatggaa taaaaaagtc
     7681 ggagaatttg taaaagaagg agaaatcctt ttggaaatca tgactgataa agtcagcatg
     7741 gaattggaag ccgaagaaga tgggtacttg attgccattc tcaaaggaga tggtgaaact
     7801 gtccctgtaa cggaagttat cggttacctt ggtgaagaaa gggaaaacat cccaacagct
     7861 ggagcagcat cgccagaagc tagctctgta cctgtagcaa gtacctcaaa cgatgatgat
     7921 aagagcgatg atgcttttga tatcgttgtg attggtggag gtcctgctgg ttatgttgca
     7981 gccattaaag ctgcccaatt cggcggtaag gttgcccttg ttgagaaatc tgaacttggt
     8041 ggaacctgct taaaccgtgg atgtattcca accaagacct accttcataa cgctgaaatt
     8101 attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga ttgaaaatcc taacttcact
     8161 gttgatatgg aaaaactttt agaaactaaa tctaaagttg ttaatactct tgttggtggt
     8221 gttgcaggac ttcttcgtag ctacggagtt actgttcata aaggaattgg tacaatcact
     8281 aaagacaaga acgtcttggt aaatggttct gaattgcttg aaaccaagaa aatcattctt
     8341 gctggtggtt caaaagtcag caagatcaac gtccctggta tggaatctcc acttgtcatg
     8401 actagtgatg acattcttga aatgaacgaa gtgccagaaa gccttgttat catcggtggt
     8461 ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat ttggttcaaa agtgactgtt
     8521 atcgaaatga tggaccgtat agttccagct atggatgtgg aagtttctaa gaaccttcgc
     8581 ttgattcttg agcgtaaagg aatgaccatc ttgactggta ctaaactgca agaaatcatt
     8641 gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag acgatatcat cgcaagcaaa
     8701 gctcttcttt caattggtcg tatgccagac cttgaaggta ttggagaggt tgagtttgaa
     8761 ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa cttcagttcc aggcatttat
     8821 gcaccaggtg acatcaacgg tactaagatg ttggctcacg cagctttccg catgggtgaa
     8881 gtttccgctg aaaatgccct taaaggaaat catgcagttg ccaaattgaa tttgactcct
     8941 gcagccatct acactctccc tgaagtagca gcagtaggtt tgacagaaga acaagcccgt
     9001 gagaaatacg atgttgccat cggtaagttt aactttgctg ctaacggtcg tgctattgca
     9061 tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata agaaatacgg agaaatcctt
     9121 ggtgtacaca ttattggtcc tgcagccgca gaattaataa acgaagcatc aagcatcatc
     9181 gaaatggaaa tcactgttga ggaaatgctg aagaccatcc acgggcaccc aacttactct
     9241 gaagtgatgt acgaagcgtt tgcagatgtt ctaggaatgg ccatccattc acctaagaaa
     9301 aaataaaacg aagatagatt agactggaag gttatttcca gtttctatca tataaagtaa
     9361 agggatatca tgaaatacat tatcaatcat tcaaatgaca ctgcttttaa tattgccttg
     9421 gaagaatacg cctttaaaca ccttttggat gaggatcaaa tcttcctact ttggattaac
     9481 aagccatcta tcattgttgg tcgtcaccag aacactatcg aagaaatcaa ccgtgattat
     9541 gttcgcgaaa atggtattga ggtagttcgc cgtattagtg gtggtggagc tgtttaccac
     9601 gatttaaata acctcaacta cacgatcatc tccaaagaag atgaaaataa ggcatttgac
     9661 ttcaagagct tctcaactcc ggttatcaat accctggctc aacttggggt taaagctgag
     9721 ttcacaggtc gtaatgacct tgagattgat ggtaagaagt tctgtggcaa tgcccaagcc
     9781 tatatcaacg gccgtatcat gcaccacggt tgcttgctct ttgacgttga tttgtcagtc
     9841 ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat caaaaggtgt gaaatccgtc
     9901 cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa aaatcacagt cgaaaaattc
     9961 cgtgatttac tcttggaata catgaaaaaa gagtacccag agatgactga atacgtcttt
    10021 tcagaagaag aattggccga aatcaatcgc atcaaggata ctaagtttgg aacttgggac
    10081 tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg gaatcaaatt cactagtggt
    10141 aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc aagacatcaa gatttatggt
    10201 gacttctttg gtattgaaga cgttgctgca gtagaagatg tccttcgtgg ggtgaaatac
    10261 gaacgcgaag atgttcttaa ggcgctaaaa accattgata tcacacgcta cttcgctggt
    10321 attagccgtg aagaaatcgc tgaagcggta gttggataaa tcaaaaagaa gttggccaac
    10381 taaccaactt ctttttttga tatttattta cataatttaa aatacgtaaa atcataaact
    10441 atccagagca ttcttttgtt catcattaac aatatgggta tagaggtcag tgacttgtgt
    10501 gctggcatgt cctagttggt gactgactaa aacttgtgat ttagtagcat catagagcct
    10561 agttgctagt gtatggcgca gtttatgggg tgttacacgt actttaaaat cctctgagta
    10621 tttagcaacc attttctcaa cgctagaagc atcgatacga ttaggaacac ctctgtagag
    10681 agttaaaaaa agggctgtat ctgttttttc cgttttatag cgttgattcc gaatggccag
    10741 ataattctct aaataaggtt tagcaaaagc agcgacattg actgagtcac gtttgccacc
    10801 ttttcgagta acatcaataa ccatcatttt tagattgaga tctcttagat ctagattaac
    10861 agcttcagat aagcgaacac cagatgccaa gagaagggca ataatggcta aatctcgttc
    10921 tttatttttg ttgaatgatg agagagctcg atttgaaagc tgttgtgggt gctcttgatc
    10981 gatataagtt agaaaacctt ctgtttcatc acctagaaag agtttttgct tgatattttc
    11041 agctctggca gcaagggttt ctttcttttt cttggttgaa acttttttca ttacattacg
    11101 atagaaataa ggttccccct gatcgttttc aacctcctcg gttagatact tgtaaagact
    11161 agaaagtgct gataaggttc gattgatagt tgtctgtgaa acaccttgtt ttgttgtatt
    11221 agcattcagc aagggacgtt cacgtagata aaggataaag gattccatgt ctttcttaga
    11281 catattttcc aaaactgata aaggaatatc ggatatttta tcagcgtttg aaataccaga
    11341 ctccaaaacc cagctgaaaa atcggtcata ttccttaagg tattcgtaca gggttgtaaa
    11401 actgtagggc acagccagtt tagattggta gtattccaga acataccagg gcatgagttg
    11461 ttttagtttg tcgattcgtt ccagtaaaat ctcacgtttc atgtattttc tccataatta
    11521 agtatactag tagtatagca tagacttgta tatttttcaa gaaaattata gtttttcaga
    11581 aagatgctat aggagttttt caaagtgata aaaagactta gacctacaaa caaaacagaa
    11641 taaggaaaat aataaaaatc tcacccacta aacttctgtt aatactacat aactgaagag
    11701 ctatataagg agctatgaga tacaaaacac attgtataat agattgaaac tagaatagta
    11761 catctggact tctaaaacat tgctagaaat tgatttgatt gtcctgattg tttt
//
LOCUS       DAVLAQ010000056        11529 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000056 DAVLAQ010000000
VERSION     DAVLAQ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.056"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            35..724
                     /locus_tag="VXB71_001657"
     CDS             35..724
                     /locus_tag="VXB71_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0451743.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPK
                     EIAQRFINVIK"
     gene            749..1666
                     /locus_tag="VXB71_001658"
     CDS             749..1666
                     /locus_tag="VXB71_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV0451744.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            1694..3235
                     /locus_tag="VXB71_001659"
     CDS             1694..3235
                     /locus_tag="VXB71_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV0451745.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGL
                     ILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIV
                     VSIIMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTENKVSAPKYTTIHDISEIKADSS
                     WEVRH"
     gene            3261..3719
                     /locus_tag="VXB71_001660"
     CDS             3261..3719
                     /locus_tag="VXB71_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0451746.1"
                     /translation="MIISEQSDFRRYASVNKHFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            3721..5943
                     /locus_tag="VXB71_001661"
     CDS             3721..5943
                     /locus_tag="VXB71_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV0451747.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLMVEQYSVSFENNKKTEYRNGTQVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            5983..7092
                     /locus_tag="VXB71_001662"
     CDS             5983..7092
                     /locus_tag="VXB71_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0451748.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            7249..8139
                     /locus_tag="VXB71_001663"
     CDS             7249..8139
                     /locus_tag="VXB71_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0451749.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWEGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLSSGDKVAKETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNVVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8164..8487
                     /locus_tag="VXB71_001664"
     CDS             8164..8487
                     /locus_tag="VXB71_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451750.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELISIESNLEMKQQNLIDEVNKTIKENDAKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            8477..10468
                     /locus_tag="VXB71_001665"
     CDS             8477..10468
                     /locus_tag="VXB71_001665"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV0451751.1"
                     /translation="MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
                     EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKVMDERFGHSIYIYE
                     SETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ITTTSDVMTILVVSVVFGFITVFVGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            10484..10960
                     /locus_tag="VXB71_001666"
     CDS             10484..10960
                     /locus_tag="VXB71_001666"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV0451752.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            10994..>11529
                     /locus_tag="VXB71_001667"
     CDS             10994..>11529
                     /locus_tag="VXB71_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451753.1"
                     /translation="MSNLENLRESVIEQAHEKGSMKLLDSKKKIDDEFEMQKSVIVKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSIS"
BASE COUNT         3880 a         1644 c         2307 g         3698 t
ORIGIN      
        1 tagtaaaaaa aataaaaaaa cggaggtttt ctgaatggaa actaaaaaaa ttaaaaattt
       61 aaaaggtcaa ataattgttt cctgccaagc gttagaagga gagccacttt atactccaaa
      121 tggaggagtg atgccgttat tagcaaaagc cgcctttcaa gcaggcgcta aaggtattcg
      181 tgctaattct gtccgcgata tttcagaaat aaaagaagaa gttgacttac caattatagg
      241 tatcataaaa agagattacg atggctttga accttttatt tcagcaacta tgaaagagat
      301 tgatgaatta gttagtgaag gagtagacat tttagctttg gattgtacta atcgttcaag
      361 accaggttat gataatatta ctgactttat tcatgatatt aaagtcaagt atccaaacca
      421 attattaatg gctgatattt ctacttttga agaagggaaa gtagctgctg aatcgggagt
      481 agattttgtg ggtacgacat tatctggtta tacaccatat agccctaaaa aagataatcc
      541 tgattttgag ttagttgaaa gattggtaaa agagcttgac gtaccagtta ttgctgaagg
      601 aagaataagt actccggaac aagctagaaa aatgttagat ttaggtgctt acgcagtggt
      661 tgttggagga gctatcactc gtccaaaaga aattgctcag cgatttatta atgtcatcaa
      721 ataaaaaaca atataaagga gaaatctgat gaaagattta actaaataca aaggcgttat
      781 tcctgcattt tatgcttgct atgatgaaaa tggtgaaatt agccaagaac gtgtaaaatc
      841 tctggtgcaa tatttcattg acaaaggtgt aaaaggtatc tatgtaaatg gttcttcagg
      901 tgaatgtatt taccaaagtg tagaagatcg taaacaaatt attgaagctg ttatggaagt
      961 tgctaaaggt aaattaacag ttatcaacca tgttgcatgt aataacacga aagatagtat
     1021 tgaattggca aaacattcag aaagtgttgg agtcgatgct attgctgcta tcccacctat
     1081 ttacttcaaa ttgccagaat attcaattgc agcatattgg aatgcaatga gtgaagctgc
     1141 gccaaataca gattttatca tttataatat tccacaattg gcaggggttg cgttgactgg
     1201 tagtttgtat gcaacaatgc gtcaaaatcc tcgtgtgatt ggagttaaaa attcttctat
     1261 gcctgtacaa gatattcaaa tgtttgtagc tgcaggtgga gaagattaca ttgtattcaa
     1321 tggtccagat gaacaatatc ttggtggtcg cttgatggga gcagaagctg gtattggtgg
     1381 tacttatggc gttatgccag atttgttctt gaaattggaa agtttgattc aagaacgaga
     1441 tttagatact gctaaaaaac ttcaatatgc tatcaatgaa gttatctata agatgatatc
     1501 aggtaaggca aatatgtatg ctgtagcaaa agaggttttg cgtctaaatg aaaaacttga
     1561 tttaggttct gttcgtcaac ccttagaagc attggcagaa ggtgacttgg aagttgcaaa
     1621 acaagcagca gaacttattc aacaagcacg aaaagaattt ttataataaa taaaatcaat
     1681 atggagatat gttatgggca caacaggatt tacaataatt gacttaatta tcttgattgt
     1741 ttatttactt gcggtgttgg ttgcaggtat ctatttctct aaaaaagaga tgaaaggaaa
     1801 agagttcttt aaaggagatg gttcggttcc ttggtatgtt acttcggtat ccatttttgc
     1861 cacaatgctc agtccgattt ccttcttggg actcgctggt aactcttatg caggtagctg
     1921 gattttatgg tttgctcaat tagggatggt tgtagctatt ccactgacaa ttcgttttat
     1981 cttacctatc tttgcacgga tagacatcga tacggcatat gattacttgg ataaacgttt
     2041 taattctaaa gcacttcgta ttatttcagc actcttgttt attatttatc aattgggacg
     2101 tatgtctatc attatgtacc tcccatcagc tggtttatca gtattgacag gaattgacat
     2161 caatattttg attattttga tgggtgcaat tgcaattgtt tattcttata ctggtggtct
     2221 aaaatccgta ttatggacag actttattca aggtgtggtt ctgattagtg gtgtcgttgt
     2281 agctttattt gtactgatgg ctaatattaa aggtggcttt ggtgcagtag cagaaacatt
     2341 agcaaacggg aaattccttg ctgcaaatga aaaacttttc gatcctaact tgctttcaaa
     2401 ctccatcttc ttaattgtga tgggttcagg ctttacaatc ttgtcttcct atgcttcatc
     2461 tcaagatttg gttcaacgtt ttactacaac acaaaatatt aagaaactta ataaaatgtt
     2521 gttcacaaat ggtgtcttgt cacttgcaat tgcaacagtc ttttacttga tcggtacagg
     2581 cttgtacgta ttctatcaag tacaaaatgc aggtagtgca gctagcaata tccctcaaga
     2641 ccaaatcttt atgtacttta ttgcatacca gttaccagta ggtgtcacag gtttgatctt
     2701 ggcagcgatt tatgcagcag ctcaatcaac tgtttcaaca ggtttgaact ctgttgcaac
     2761 ttcatggaca ttggatattc aagatgtcat ttctaaaaat atgtcagagg atcgtcgtac
     2821 gaaaattgca caattcgtat ctctagcagt aggtttattc tcaattgttg tttccattat
     2881 catggctcat tcagatatta aatctgcata cgaatggttc aatagtttca tgggacttgt
     2941 acttggtcta cttggtggtg tattcattct tggttttgtt tctaaaaaag caaataaaca
     3001 aggtgcttat gcagcgctga ttgtatcaac catcgttatg gtatttatta aatacttcct
     3061 tcctccaaca gctgttagct actgggcata ttcattgatt tcaatttctg tatcagtagt
     3121 ttcaggttat attgtatctg ttcttactga aaataaagta tctgcaccta aatatacaac
     3181 gattcatgat atttcagaaa ttaaagcgga ttcaagttgg gaagttcgtc actagtcact
     3241 aatagaaaag agaaaataat atgattattt ctgaacaatc tgattttaga cgatatgctt
     3301 ctgtcaataa acatttttca aaagtctgtg attttttaga aaatacaaat ttgacagatt
     3361 tagttgatgg aaaaattgat attgacgggg aaaatgtttt tgcaaattgt atgacttatc
     3421 tagctgatgg agttccagga gatatttttg aaactcataa gaaatattta gatattcata
     3481 ttgttgttga aaatacagaa aaaatggcag taacttcccc agttcgtgct cagtcacgtg
     3541 taccttttag cgaagagaag gatattgctt tttacgatag caaagactat caaattgttg
     3601 aattgcttcc agggaatatg ttggtgactt ttgaagaaga tcttcaccaa ccaaagattc
     3661 attgcaatga tgaaactgtt aaaaaacttg ttatcaaagt tttaaacgag gaaaaataaa
     3721 atgaaaaaaa atattaaaca atatgtaacc ttaggtactg tagtggtatt atcagcattt
     3781 gttgctaact cagttgcagc tcaggagact gaaacttctg aagtatcaac accagagttg
     3841 gtgcaacctg ttgcaccaac gacttcgatt tcggaagtac aacataaatc gggtaactct
     3901 tcggaagtta ctgtacaacc tcgaacagtt gaaactactg ttaaggatcc atcttctaca
     3961 gcggaagaaa ctcctgtctt agaaaaaaat aatgttactt taacaggggg cggagaaaat
     4021 gttactaatg agttaaagga taaatttact agcggtgact ttactgtagt gattaagtac
     4081 aatcagtcta gtgagaaagg tttacaagct ctgtttggaa tatctaattc taaacccggt
     4141 caacaaaata gttatgtaga tgtgttcctt agagacaatg gtgaattggg aatggaagcg
     4201 cgtgatactt cttccaataa aaatcaccta gtaaccagac ctgcttcagt ttggggtaag
     4261 tacaaacaag aggccgtgac gaacactgtt gcagtagtag cagattcagt caaaaaaacg
     4321 tattctttat atgcaaatgg tacaaaagta gtagaaaaga aagtggataa cttcctaaac
     4381 atcaaggata ttaaaggtat tgattactat atgcttgggg gagtgaaacg tgcaggaaaa
     4441 acggcgtttg gttttaacgg aacactagaa aatatcaaat tctttaatag tgcattggat
     4501 gaagaaactg ttaaaaagat gacaacaaac gctgttactg gacatttaat ttatacggct
     4561 aatgatacaa caggttctaa ctatttccgt attccagttc tgtatacttt tagcaatggt
     4621 cgggtttttt caagcattga cgctcgttac ggtggaactc atgatttctt gaataaaatt
     4681 aatattgcta caagttatag tgatgataat ggtaagacat ggactaaacc aaaattaaca
     4741 ttagcattcg atgattttgc gccagcacca ttagaatggc ctcgtgatgt tggtggacgt
     4801 gacttacaaa tcagcggtgg tgcaacctat attgactctg ttattgttga aaaaaataac
     4861 aaacaagtac tcatgtttgc tgatgttatg cctgctggag taagttttag agaagctact
     4921 agaaaagatt caggttataa acaaattgat ggtaattatt accttaaatt aaagaaacaa
     4981 ggtgatactg attataatta tactattcgt gagcatggta ctgtatacga cgatcgtacc
     5041 aacagaccaa ctgaattttc agtagataaa aatttcggta ttaaacaaaa tggtaattat
     5101 ttgatggtag agcaatattc ggtttcattt gaaaataata aaaagactga atatcgtaat
     5161 gggactcaag tccatatgaa tatcttctac aaagatgcat tattcaaagt agtgccaacg
     5221 aactatattg catatatttc tagcaatgat catggcgaat cttggtctgc accaacttta
     5281 ttacctccta taatgggact taatcggaat gcgccttatt tgggtcctgg acgtggaatc
     5341 attgaaagct caactggacg tattcttatt ccgtcttaca ctggtaaaga gtctgcattc
     5401 atttatagtg acgataatgg agcgtcttgg aaagttaaag ttgtgccact tccttctagt
     5461 tggtcagcag aagcacaatt tgtagaattg agtccaggag taattcaagc atacatgcgt
     5521 acaaataatg gtaaaattgc atatttaaca agtaaagatg caggtactac ttggagtgcg
     5581 ccggaatatt tgaaatttgt ttcaaatcca agttatggaa cacaattatc aatcatcaat
     5641 tatagtcaat tgattgatgg taaaaaggct gtcattttaa gtactccaaa ctccacaaat
     5701 ggtcgtaaac acggacaaat ttcgattggt ctaattaatg atgataatac aattgattgg
     5761 cgttatcatc acgatgttga ttatagtaac tatggatact catattcaac attgacagag
     5821 ttaccaaatc atgaaattgg attgatgttt gaaaaatttg attcatggtc tcgtaatgaa
     5881 cttcatatga aaaatgttgt accatatata acatttaaga ttgaagattt gaaaaagaat
     5941 taaagctgaa atttaaaaat atatagaaag aggataaaaa ttatggtaaa ttacggtatt
     6001 gttggagctg gatattttgg agctgatttg gctcgctcaa tgaacaaaat tgaagatgca
     6061 aaagtggttg cggtatttga cccaaatcat ggagaagaag ttgctcaaga gttgggatca
     6121 gatgtttgtg caagtttaga tgaacttgta gcacgtgaag atattgattg tgtgatcgta
     6181 gcttcaccta gctaccttca ccgtgaacct gttgtgaaag ctgctcaaca tggcaaacac
     6241 gtattttgtg aaaagccaat tgcattgtct tatgaagatt gtaaagccat ggttgacgca
     6301 tgtaaagaaa ataatgttat ctttatggct ggtcacatca tgaacttctt taatggtgta
     6361 caccatgcta aagaattgat tactcaaggt aaaatcggta aagttcttta ttgccatgcc
     6421 gctcgtacag gttgggaaga acaacaacca actgtatcat ggaagaaact tcgttctcaa
     6481 tctggaggac atttgtacca ccatattcat gaattagatt gcattcagtt catcatggga
     6541 ggacttcctg aaaaagcgac aatggtagga ggcaatgtat atcataaagg tgaaaacttt
     6601 ggtgatgaag atgatatgct cattgtaaac ctagaatact ctgatgatcg ttatgctgtt
     6661 ttggaatatg gtaatgcttt ccgttggggt gaacactacg tcttgattca aggaactgaa
     6721 ggagctatca aacttgactt gttcaatact ggaggtactc ttcgtgttaa aggtgaagga
     6781 gaatcacact tcttagtaca tgaaactcaa gaggaagatg atgaccgtac agctatctat
     6841 accggtcgtg gtatggatgg agcaattgcg tacggtaaac caggagtacg ttgcccatta
     6901 tggttacaaa catgtattga taaagaaatg gaatatctac atgacatcat taaaggtgga
     6961 gaaattacag aagaatatga aaaacttctc aatggtgtag ctgctttaga atcaatcgct
     7021 accgctgatg catgtacttt atcagttaaa gaagatcgaa aagtaagtct ttcagaaatc
     7081 acaaatgctt aactattgta aaacagaata gtaaattctt gtcattatat aatttctaaa
     7141 gttctgtgat acaactcatt gaataaagaa atagagatgg gactgggata atgcccagtc
     7201 ccatttttta tcaaaaagta atgagatcaa aaatgtggga gtgatgaaat gaagattata
     7261 gggatcgata ttggcggaac aacaattaag gcagatttat acgatgattt tggaacgagt
     7321 ttaaatcagt tcaaagagat agaaacaatt attgactatg atttgggaac gaaccagata
     7381 ttaaatcagg tctgtgattt aattggtgag tatgttttaa attattcaat tgatggtgtt
     7441 gggatttcca ctgctggagt tgttaatgct aatacaggag aaatcatcta tgcaggctat
     7501 acaataccag ggtatatcgg agtaaacttt acttccgaaa tagaaaaacg ttttgggttg
     7561 tctacttttg ttgaaaatga tgttaattgt gctgcattag gtgaattgtg ggagggacaa
     7621 gccaaagata agaaaaatgt agtaatggtt actattggaa caggtatagg aggcagtatt
     7681 attgtcaatg gacaaattgt taacggattt aactatactg ctggtgaagt aggctatatt
     7741 cctgtaggta attcggattg gcaaagcaaa gcctcaacaa ccgcattgat tcatttatat
     7801 caaaagaaga gcttgaaaac taatcaaact ggacgtactt tctttactga tttaagttct
     7861 ggagataaag tcgctaaaga aacttttgaa atttttgtag aaaatctaac aaaaggttta
     7921 ttaactattt cttatctact taatccagaa attctcatat taggaggtgg gattctggct
     7981 aaaaaggata ttttgttacc tgaaattcaa agttctttag ctaaaaatgc aatggataat
     8041 aggtttttgc ctaaaaatgt tgtggcagct acattaggaa atgaagctgg tcgtatagga
     8101 gctgtaaaaa atttcttaga tagaatttct aataaatagt gtgaaagata aggaggtgtc
     8161 acaatgacta actctgtatt ttcgacaatg caagatattg agaatgttgc aaccgatatt
     8221 ataaaatcat atgataatga gatttatacg tataaagctg tctcccaaga agaattggaa
     8281 aaactagaaa aaagttatga tgaaaaaagt cacgaagaat taatttcaat agaaagcaat
     8341 ttagaaatga aacaacagaa cctcattgat gaggttaata aaacaatcaa ggaaaatgat
     8401 gcaaagattc agtatatttc atcaagtagg agaggagaat ttgtagaaaa aattattggt
     8461 agggtggtag aaaaatatgg ctattagtca gatgaaaaga atttctctac tatttactaa
     8521 gagtagtctt gatgatgttt taaaaactat tcaagaacta gagtcagtgc agttccgtga
     8581 tttaaaggtt caggataact ggtcagaagc gctagaaaaa gatgaggttg tattttcaac
     8641 tattcaaatt tctcacactt ctaattccca tcatggggtt attgaaggaa atgatgcctt
     8701 gaattatttg atgaataaac aacaacattt ggaagcaact gtagagaaat tacaagaata
     8761 cctaccgaaa gaaaacacgt ttaagttatt acagcaacct ccgataacaa cctcttatga
     8821 agaattagaa aaatttggta aagctaatgt tgctgagggt gttcttaaaa aagtgaatca
     8881 tcaaataaac agagttcatg aattagaaag aaacattcaa agtaataatg aggaaataga
     8941 gagattaata aagtgggaaa aattagaaat tattcctgcg catttagaac aattttcttt
     9001 ctgtagagga aaagtcggaa caattccaag gactgtagat aatcgcttat acaataattt
     9061 tttagaaaac aatattgaag ttcaagaaat attttctaat gatagagagt acggtgttgt
     9121 tgttttctat cagtccagtt gctctattga ttttgatgaa tacttatttg aaccatttga
     9181 ttattctaga aaggaattac cgaagcagcg agtagtagat ttggatcaag aaaacatgca
     9241 gttaataact gaaaaagaga atattatcgc atcgttgcaa gattcaaaga aaaatttgat
     9301 agatttacaa tggcaaattg actatatttt atctatctat gctcgtcaaa tctctaagaa
     9361 taaccttttg agcactccgc atctagttgc attagaagga tggatagaag aaactcgtat
     9421 tttatatttt ataaaagtta tggatgagcg ttttggacat tctatttata tttatgaatc
     9481 ggaaacattg tcggataatc aagatgaaat acctatcaaa ttaacgaatc actctttaat
     9541 tgaaccattt gaattattga cagaaatgta tgctctgccc aaatattatg agaaagatcc
     9601 tacacctgta ttagcaccat tttactttac attttttgga atgatggttg ctgatttagg
     9661 ctatggttta ctattgtttt taggaataat gttagcatta aaaatttttc atctaccttc
     9721 agtaactaag aaatttttaa aattctttaa tatattaggg gtagccgttg caatttgggg
     9781 tggaatctat ggctcatttt ttggatatga gttgccattt catctgataa ctacaacctc
     9841 ggatgtcatg actatattag tagtgtcagt tgtgtttgga tttattacag tatttgtagg
     9901 tttgttagct tcaggactac aaaaagtaag aatgaagaaa tatgcagaag catataattc
     9961 aggatttgcg tggtgtgtta ttctgcttgg cttgttattt attgctgtcg gaatgttgat
    10021 gcctgatatt agaccgttat ttgtattagg gaaatgggta tctattttta atgctgtggg
    10081 gattttgatt gcttctatta ttcaagccaa aagcttgtca ggtattggct caggattgtt
    10141 taatctatat aacatttcat cttatatagg tgatttagtt agtttcactc gattgatggc
    10201 attaggatta tctggagcaa gtatagcatc agctttcaat ttaattgttg gtttgtttcc
    10261 ggggacattg gctaaactga caattggatt agtattattc attcttttac atgcgatcaa
    10321 tatttttcta tcgttactat caggatatgt tcatggagcg cgtctgatat ttgttgaatt
    10381 ttttggtaag ttttatgagg gtggaggaaa accatttcaa cctttgaagg cttctgagaa
    10441 atatattaag gttattacaa agaattaatg gaggatatat ataatggaac atttagcaac
    10501 ttatttttca acctatggag gagctttctt cgctgcattg ggaattgtat tggcggttgg
    10561 attaagcggt atggggtctg cttatggagt tggtaaggct gggcaatctg ccgcagcttt
    10621 actgaaagaa cagccagaaa aatttgcctc agctttgata ttgcaactat tgcccggaac
    10681 acaaggatta tatggttttg ttattggaat tttgatttgg ttgcaattaa ctccagaact
    10741 tcctttggaa aaaggcgttg cttatttctt tgtagctctt ccaattgcta ttgtaggata
    10801 cttttcggct aagcatcaag gaaatgtagc agtagcggga atgcaaatct tggctaaaag
    10861 accaaaagaa ttcatgaagg gagcaatttt ggctgccatg gtagaaacct atgcaattct
    10921 tgcctttgtc gtatcattca ttttgaccct tcgtgtataa gaaattaatt tgctattcaa
    10981 aggaggtgtc taaatgagca atttagaaaa cttacgagaa tctgttattg aacaagctca
    11041 tgaaaaaggg agtatgaaat tattggattc caaaaagaag attgatgatg aatttgaaat
    11101 gcaaaagtcg gtcattgtaa agaaaaaaga agctgaacat gaacgaaagt taaaagaatt
    11161 acaacagaaa tatcaaataa tttttcaaca attaaaaaat aaggaacgcc aatcaacgtt
    11221 agtatcaaaa cagaaaatat taaaagaact ttttcaatct gctttaatag aaatggaatc
    11281 ttggagtgca gataaagaaa tggagttcat ctatcgaatt ctggaacgat attcacaaca
    11341 agaggtcata gtaacttttg gggagcggac tttagctaaa ttcaatttgg aacaattaga
    11401 gaaattgaaa ttctcttttc caaatcattt atttagtgaa cagcctatct caaatgaatc
    11461 aggcttactt atttcaatag gtaaaattga tgataactat ttgtataaaa cgttaattgg
    11521 atcgatttc
//
LOCUS       DAVLAQ010000057        11337 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000057 DAVLAQ010000000
VERSION     DAVLAQ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11337
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.057"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..673)
                     /locus_tag="VXB71_001668"
     CDS             complement(<1..673)
                     /locus_tag="VXB71_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451754.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFT"
     gene            complement(683..1435)
                     /locus_tag="VXB71_001669"
     CDS             complement(683..1435)
                     /locus_tag="VXB71_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451755.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(1435..2199)
                     /locus_tag="VXB71_001670"
     CDS             complement(1435..2199)
                     /locus_tag="VXB71_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451756.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(2295..2698)
                     /locus_tag="VXB71_001671"
                     /pseudo
     CDS             complement(2295..2698)
                     /locus_tag="VXB71_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2878..3510)
                     /locus_tag="VXB71_001672"
     CDS             complement(2878..3510)
                     /locus_tag="VXB71_001672"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0451757.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(3544..4245)
                     /gene="pyrF"
                     /locus_tag="VXB71_001673"
     CDS             complement(3544..4245)
                     /gene="pyrF"
                     /locus_tag="VXB71_001673"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0451758.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            complement(4478..5677)
                     /gene="divIB"
                     /locus_tag="VXB71_001674"
     CDS             complement(4478..5677)
                     /gene="divIB"
                     /locus_tag="VXB71_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0451759.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(5687..6745)
                     /locus_tag="VXB71_001675"
     CDS             complement(5687..6745)
                     /locus_tag="VXB71_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0451760.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(6749..8101)
                     /locus_tag="VXB71_001676"
     CDS             complement(6749..8101)
                     /locus_tag="VXB71_001676"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0451761.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(8205..8846)
                     /locus_tag="VXB71_001677"
     CDS             complement(8205..8846)
                     /locus_tag="VXB71_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451762.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(8848..10869)
                     /locus_tag="VXB71_001678"
                     /pseudo
     CDS             complement(8848..10869)
                     /locus_tag="VXB71_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(10952..11251)
                     /locus_tag="VXB71_001679"
                     /pseudo
     CDS             complement(10952..11251)
                     /locus_tag="VXB71_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
BASE COUNT         3589 a         2455 c         1929 g         3364 t
ORIGIN      
        1 gagtgaaata gaaaatactt ttaaaaagaa agactaaaaa tagcaactga agaaataaat
       61 ctcgtcctat atctccattc cctcgattca aaatataaaa tagataatta gttcgatttc
      121 ctacaaatag accaccaaac acaatcatga gtaaaaagaa actaacgcaa gcaaagttca
      181 tttgtacatt cgctcctagt gcgtataaca taaagcaaaa caagactaac acacaagcat
      241 tcaaagaatc aactataaac aaaactccta tatcccagtt tggtaactgt aacataaatt
      301 gaatcactag aacttttacc atgattaaaa tgagtccata aagaaaacag gtccaaatct
      361 gatacctaat ccagagctta atagaagaaa atcgaatcac ttccataaag aaatcggatg
      421 ctcttctacg atatacaact gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc
      481 atatagataa gactaaaaaa gagttttgac tcagattagg cccttttaaa atttctataa
      541 caagtctatc atttccttct aaccaatacc ataatcctaa acaaatcaat atccaaaaaa
      601 gaacataacc ccaaaagtac ttggtataga ttatctgatt caacctccac atgtgactac
      661 ttaactttcc catttccaac ttttacactc tcctccagtt tctatgaaca gaaaatacag
      721 tcaatggaat tatgatagat agtaatgtaa gccaataaat caatgcatac ggattggaat
      781 ttaccatata ctgaaaaatt ggcaataatc caattatccc attgtccaac tgataaatcc
      841 agaataagga ttctacaaat aaaaaagtaa acagaaatac taagctcatg tttgattttt
      901 taaaccaaga aaaactgcta atagtaagta aggataaaaa gaaatagtat gctatataag
      961 agaaaaaaaa tcctataaag aaactagcat tgtttgcaat acttatacca taaaattctc
     1021 ttaaaaaatc aacctccttt atctccaaag agaagctaaa accattacta aatgcaatta
     1081 gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt actaagagct gctaatttga
     1141 aactaaaact ggtaaagtgc ttaattgatt tcagacgaat gcgacactcc aacctattaa
     1201 aatagttatt catcaaataa aaaaagaaca atatatatgt gaacggaaag caatatactc
     1261 cagtcgtcat atcttgaagt aaaactaaga tccattctaa tacatttgga tggattgaat
     1321 attggcgaca gcgcaataaa tatactgtac tagataaaac acaggatagc agtaatataa
     1381 aataaaccaa tactgataaa aaatcttttt tgtaaaattg aacaaattgt ttcattatac
     1441 gtagtcctct gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa caaataaaat
     1501 aaaagcaaga tgcccactaa ctaaggaaag actgatatct ttctgatatc ccaaagctaa
     1561 tgttgtcaca ggttctaagt aagatagccc taaaatagcc caaaaaatac caccaaccat
     1621 catataggca actgggatga aaatagctcc tatttttttc ttcactagca aagcactagc
     1681 tagtccaaaa atagagaaca cagcgcccca aactccatac cagagagtcg ttacaagact
     1741 atagagaaac tgattggaat caaataattc ttttaaggca ccactataat ctccaatata
     1801 aatttcctga taaggagtca ctaaaagatt aattcctaat aataataaat aggggagaaa
     1861 aaagactaga aaagaagaaa taattacagt actacccaca atagccagat acttcttttt
     1921 agaaattcga cacaattgtg ctgttagaaa atgactctca gcatcctcta ttatctgact
     1981 agaatagggc agtgtacaga taagtgcagc tactaggcta atcggtgaaa atcctcgaat
     2041 agaagaagcg gcaaaaaaaa tcgataaacc ttcaatttta taaataccat tgaaagcaag
     2101 gaaatttcct aaactcatgc aaagaagggt caaaaataaa gacatataaa atcgaggtga
     2161 ttgaacgact cgtacaagat tacaaatgaa aaattccatc cttactcctc cttataataa
     2221 aaatagggtg tagcattctt ttttcatgct acacccacaa tcaaccatct ctaaggctta
     2281 ctctgacaag taagttaata agaatctgga ttccaagaac ctgaagtatg aattcttaca
     2341 tgatttccaa attgtggcgc catagctaat ctagtaccag aaccaatata attgtcacca
     2401 cctccattat agtacatgac aatcctagag ccagacccca atgaatatac cggggtaata
     2461 tctgacccac tataggcgct acgaatagag gtatttaacc ttttaccgcc accagtgctg
     2521 tcattattat taattccagc agaggcgttt tctttctcaa gctcactagt tgtatccgaa
     2581 ccccaacgcg gcaacgttaa atcataatct ccaatctgtc tagctaaaac tgtaaggaga
     2641 aacaaactag atgcaattgt aactacgcaa aaaaggaata tatttttctt cttttcatga
     2701 catcgtcctc ctaagaagtg ataaacaaga tagttgattg atcaatttga tacatattac
     2761 attttcatta tatcaacaaa agaaagcgtt gtcaatcatt ttatttaaaa tattgtcata
     2821 ttttaaataa aatgataaaa gaggctcggt agcctcatct ctctttatct tactgaccta
     2881 accttcttgc caattttctt ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg
     2941 cgtgatgtaa ccttcttctt gggctagatg gataagctcg ctatagtttg aaagcgtcac
     3001 aagtttaaca ccagcatctg caaagttctt atctgctttt ggcaattggt agctgaaaat
     3061 cgctacaact ccaagcacat ctgctccttc tcgcttggct gctgctacag cttcaagaac
     3121 tgaaccaccc gttgaaataa ggtcttcaac cactaccatt ttttgacctt gagctacgcg
     3181 accttcgatt tgattaccag ctccgtggtc ttttggtttg ctacggatgt aggcaaaagg
     3241 caagtccatc ttatcagcaa taatggctcc gtgtggaatc cctgctgttg cagttcctgc
     3301 aatcacttct acttcaggaa aggcttcttt gatagcttcc acaaaaccat tttcaattag
     3361 ggtacgagtt tctggatagg ctagtgtcac acgattatca gtgtaaatcg gtgacttgat
     3421 accagatgcc caagtgaagg gttcctctgg tttgaggtaa acggcttgga ttttcaagag
     3481 gtggctagcg atatctttag caagtgtcat ggtattctcc ttttattttt ctaatctagt
     3541 tctttaattc cagtcctgtg tccattcatc cttgatggta tgataagctg caacaggatc
     3601 ctcagcttgg gtaatgggac gtcccactac gatatagtca ctgccgattt gataggcatc
     3661 agcaggtgtc atgactcgtt tttgatctcc aactgcagca ccagctggac gaatccctgg
     3721 tgtcagacag ataaaatctg gattggtagc ctgcttgatg acttgtactt cctgagccga
     3781 gcaaacaaca ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa tcacagactc
     3841 ttgcagactg gtttggatat tttgaaactc ctgcatctga gcttctgacg ttgatgtgag
     3901 ctgagttaca gcgatcaatt tagcttgact cccaaggcct tcacgcgccg ccttcatcat
     3961 ctctacacca ccagccgcat ggacattagt catatcgaca ccaagctgag acaagacctt
     4021 catggctgac ttgactgtat taggaatgtc atgaagtttg agatccaaaa agacactatg
     4081 acccaaacct tttaagtagg acacaatctc aggccccgct gcgtaataaa gctccatccc
     4141 taccttgaga taaaggcttt cttctgctgg gaaaagagct aaaaattcct tgaccgcctc
     4201 aaaactagga aaatcaagag caatgactgg acgatgttct cgcataggtt tctcctttta
     4261 cctttactag tgagagagtc tggccaacag aagccacgaa aaaaggaacc tgccaacagc
     4321 aaggttccac gaaaaatggg tagtctccac cctttcaccg tctaacctta gctgcctctc
     4381 tggactgctt taaaggtttt ttactattct attatttcta ctagcacttg tcaagtaaaa
     4441 acatggtcac taaagaacta taagagaaaa ggtaaaccta gcgacgcgat gagcgctggg
     4501 tcgtttggtt tcgattgctc tcttcctctt gttttttctg ttcttcttct tgttttttct
     4561 cagcttcctt agcctcttgt ttggcttttt cctcagcttc cataattaat ttatccgcca
     4621 cagtgtaact gtaaattcca gcttccatgt caatcacact cggttctgac aattgtggct
     4681 taatcttact ataataaggc agtttcttgc tcatttcaga aagcggaacc aagacttcgt
     4741 ccaaatcatt catagtcaat cgaattaaat cggatgtcac cttgcttggg gctaattcca
     4801 ccttttggat agccgccttg agttctgggc taatttgagc aagttctgag acaaaaacct
     4861 tgatttgttc actatcatta aagagaactg ataaataagt ttctggtaaa ctgttcaggc
     4921 tcacagaact agtctcaagc tgaccactgg aaagaatagg ataatgattt tcaccagaaa
     4981 tatagtaggc cacaatatca tattccttga ccttaatagt gaacttagtt ggaaattgat
     5041 agacaagttg agctgattca acccaatagt tagacttaat ctgcttttca tattttgcct
     5101 tgtctagcag aaggttaatc gtataatccg aatcctgaat gcctgaagcc tgtcgaatat
     5161 catcagctgt agtttgcacc gttccctcaa cacgaatatc tttcatggtc gcataaggac
     5221 tgagcaagta ggcagagaca atcaataaaa gcagacttgg aaataaaatc gtgaaggctc
     5281 gcaagatatg gataccagga atctttgctt tggctggttt ttcctttgta gcctttttag
     5341 caagcttttt atcctgttcc tccttctctt tagactctgg ttcttctttc tcttctttct
     5401 ctttgtcatc ctctgaggat gctacttttt cttcagactc ttccttagct gattctgaat
     5461 cttcctggtc tgtttcactc tcctggtcct gtttgtcctc tgacttctca gattcttctc
     5521 ccatccgagc ttgtctttcc ttttccttct cctcagctag agccgcttct tcttcagcct
     5581 tcttttttag atattcttgg tttcgtttct gccattctga taactctttc aattcttcga
     5641 ggatttcttt gtcctcattt ttcttatctt ttgacattta ctttccttat gataaatctt
     5701 ttttcaacaa ttgataaaaa tctgctagag atttcaattc cttagaagct ttcatcttag
     5761 cttggtaatc ttccttgtga cttagtaagt gagaaagctt ctcttccaaa ctatccaagg
     5821 tcaaatcgct ttcttgaagg tcttctgcat agcctttttt tacaaagtaa gctgcatttt
     5881 caatctggtc accacgacta gcttcacgac caagcggcac aatgacatgc aattttgcta
     5941 tcgccaagag ctcaaaaatc gtattggcac cacctcgtgt cacaacaata tcagccaatt
     6001 ccaacaaggg ttgatagaga tcggtcacat agtcaacacg aaaaagattt tggctcaact
     6061 cattcaggct agaatctcca gttagattga taatattgta gcgctctgtt agttctttct
     6121 tatggtctgt caccaattgg ttaaagacac gagcacctgc agaaccgcca acaaacaata
     6181 cagtcggcaa tttatgatta aagtgggttt gaatatccac caattcatct ggttctggat
     6241 ttttttgatc tgaaaccttg gtcactgctc ccacatgctc aaccttagac aaactcgaag
     6301 cttgctcaaa ggttgaatac atcttagtcg caaatttata ggcgatttta ttggccaagc
     6361 ccatagacag gtcagattcg tgaataaaga caggcactcc tgacacacgc gctgcgataa
     6421 caggcggtac tgagacaaag cccccctttg aaaaaagggt ctgtggacga agtcgcaaca
     6481 tgataaagag cgattggacg attccccagc caactttgaa gacgtccagc atattttgcc
     6541 aagagaaata gcgacgcaat ttcccagtcg caatggagtg gaaagtgaca tccaaacctg
     6601 acttaaggat ttcttggtgt tcgataccac gcttgtcccc gatatagtgg acttcccaac
     6661 catcttcgat gaacttgggc attaacaaaa gattgagggt aacgtgtcca accgtccccc
     6721 cacctgtaaa gacaattttt ttcatatttt attcttttaa ctccgctact gtgtcgataa
     6781 agaggtcgcc acgtacttca aagttagcat acatatccca gctggcattg gcaggactaa
     6841 gaagaaccac atctccttga gtcgcaagct cataggcctt gcgggtcgca tctgcaatat
     6901 ctgtcgcctc cacataagcg acaccagcct tgtctgctgc ccgtttgaca cgttctgcag
     6961 attgacccag gatgaccatc ttcttgagtc cagtaatgtc tggcaccaat tcgtcaaact
     7021 cattgccacg gtccaaacca cctgcaatca agacgacctt gctgttgtca aatcctgata
     7081 aggctttttg agtagccaag atattagttg atttactgtc gttatagaat ttaacaccct
     7141 tgatgtcatc cacaaactgg agacggtgtt tgacaccacc gaaggctgaa agagtttcct
     7201 tgatggtttg attgtccaca tcacgaagct tggctacagc aatagtcgca agggcatttt
     7261 ccacattgtg gctacctgga acaccgattt cattcgctgc catgactact tcaccacgga
     7321 agtagagttg accatcttcc agataagctc catcaacctt ttcaagtgtt gaaaatggta
     7381 caacagtggc ttctgtcttg gaagccaagt cttttaccaa gtcttgatta aagttcaaga
     7441 caaggaaatc agctgctgtc atcttgttct ggatattcca cttggctgct acatattcct
     7501 caaataatcc atgataatcg atatgagttg gcatgaggtt ggtaataacc gcaatctctg
     7561 gatggaattc ttgaacaccc atgagttgga aagaagaaag ttccataaca agcgtgtcct
     7621 tatctgatgc tatttgagca acctgactgg caggatagcc gatattccct gataaaagac
     7681 catgttgccc agcagcagtc aaaacttccc caatcatagt cgttgtggtt gtcttaccgt
     7741 tcgatcctgt gataccaata atcggtgctt ctgaaatcaa ataagccaat tccacctcag
     7801 tcaagactgg aattcccttg gccaaagcct tttcaatcat gggattgctg taggggatac
     7861 ctggattttt taccatgagg gcaaactctt catccaagag ttccaaagga tggccacctg
     7921 taatgacctt gatcccttct tccagcaaac attgggcagc tggattgtcc tcgaatggtt
     7981 tcccatcatt tactgtcaca atggcaccta acttgtccaa caaacgagcc gcagattcac
     8041 cagacttggc caaacctaaa acaagaactt tcttattttt aaattgatct attactttca
     8101 tgtctcgaac tccatttcta ctcctactat tttaccattt ttatggaaat aaaaaagcca
     8161 caaagtgtgt ttgtgactct ttcttctaac tgaatcttac catatcatct atgtgataaa
     8221 tcggtaactc gaatgacctg atccacttgc tcccaaatca gaggattgtg ggtcgcaata
     8281 ataatggtcc gattcggatt ttttaaagat tctaggatgg aaagtaattc ctcagaattt
     8341 ttggggtcta aggaagcggt tggttcatct gcaagaatca aaggcggatc ctttaaaatt
     8401 atcttcgcta gtgcaacacg ttgtgcttct cctcctgata actcaaatat aggttgcttc
     8461 aaatccaaat aagagaggtt tacacagttt agagcttgtt tcatcaaaga gattttctct
     8521 ttttccttca actttttacc aactaaaccc agattgagat tctctttgac ggtttggctt
     8581 tcaattaagc caaaatcttg aaataagtat cctaagtaat ctctaaagaa aacagaaggc
     8641 ttgatgtcct taagagaagt gccatcatag atgatttgcc ctttgtcata tggctccaat
     8701 cgtccaatca tattcaagag tgttgtctta ccacagccac ttgtaccgat taaggcataa
     8761 attttcccac cttcaaaatg aagattcgta tctgaaaata gctgacggct tccaaatttt
     8821 ttagatatat tctttagttc aatcatccta ttttcctttc ataattgtca tagaaacacg
     8881 agattctttc tgcgcttgac ggtaaagcgt caaaactgca ctagctagaa agaccaataa
     8941 agtgagcaag ccaatcacca agtctcgact gcttaaaata aagagactag caccaaatac
     9001 aaaactggca aattggctaa ccatatactg agcatgtgtt tcaaaaaatc gtaaacctga
     9061 aattcgttta atcaagatat ctcggcggaa ttgctcgaaa tatagaagat tgacagaata
     9121 aaatagtaat aaggaactag ctatccccac aatagctcct aagattaaag ttgctgtttc
     9181 agtttgaact tcattataac gagttagata aacacttctt ccttctttaa gataggatac
     9241 ttgctcataa attccagctt tcttcaagag ttctagccca ctctcatatc ctttgataaa
     9301 gagttgtttt ccagcattga tagaccaact agataaggat ataaaactat cacctgtaga
     9361 agtcggcgtg aataccacta aaatcggatc agtcaaatac tgagtagata cgggattctc
     9421 accgttatta taaacaaacc gcttttctcc cattgaaaga taactaacgt gcgctttcat
     9481 ctcataatcc aaaggagcac ttgcctcctc accagatttt ccataataac tcaatctttc
     9541 ttcaaaaact ttcttaagtt ctgcttctcg agagcgcaaa tgttctggga gcaagaggat
     9601 aaactcacct ttttggagat gggctaactt ctgtttggtc tcagcatcta ccacgacctt
     9661 ttccttgtcc aaataactgg gactaacata gagcgtatta gcatctggac tataggtatc
     9721 cagtgtctct ccctgttcat tttttccttg tggattggca aaatggagca gattatcctt
     9781 tacataaaga gcttgttcct cttcgattgc ttccttggca aaggcatacc acttgctctg
     9841 attttctgta tcttttcctc tatcacctaa gccaaaagaa atttgataat agtctgctct
     9901 atcctgccat gcttgttttg aaatttcaag ttctttcaat cgttggtaag acgtcaaacc
     9961 tgtcttaaca gcgtatccta ctgtaaagac agcaaccaac tgacacaata gggttaaaat
    10021 catcaggcgt ttaaggggta atctcccctt aataacggga actaatgctt tgtaactcaa
    10081 actcattaga taaagaagca ttagtaaaat tgaaatcgcc aataaaaaca acagatagaa
    10141 actaatccca aaaccatagg tggctaacaa gataggataa aacaaacctt gactaaaaag
    10201 aacgactccc ccacctagga aggaaaggag ggctgataga aggagctatt tgatatcagt
    10261 agataaagaa tgccccatga tggataagag agtctgacca gaaaagagtt ttatacctgc
    10321 tgctctcatt tccttaatcc gagtgataat cactaaagca aagaaagata agccaaatat
    10381 tgctaaacta attaaaataa ggggatttag taatattcga aaagcaagaa aatagggcgg
    10441 tatctttcgg tcagcacttg ctttataacc caaatctcct aatttatcgg caagcttttc
    10501 tttcgtcaag gagcctgaca aaaggagata actatttagc ggatcactac gttcacgact
    10561 ttcttggcta gcttcttgga attcttttgg taaagttccc tgaccataag ttgcataagt
    10621 aaagtgagtc gtcccatcct tactcggctc tacaattctt ctagctatta aactctgttc
    10681 tgagtttgca aaattctcca attcctgttc aaatacctca cgcgtcggtt cctgagtatc
    10741 ttttttgaca cgaagtaaag aaacggaatc atagcttgca tataaatatt gtggcgcacg
    10801 taagacaata atccaagcaa ggaagaagct gagaaaaaaa gttgataata atatgaatag
    10861 tttcttcata gtagactcct tggtagactc cttgtaaaca aaattccccc tgtaatttct
    10921 tacaagggga acgatttaaa tcaatgaacg attagtcata atcacagtaa aatgctactt
    10981 gttctcccca tttagtccaa atccatgcat aggaggtttt tccagcagga gcttctcctt
    11041 tatcagaatg accatcccat ctgctcacga tggatgaata atgatatttt ttaccatgat
    11101 agtaatttga aaaagcctaa ccacctcctg aaccttctcc atatgtccat actcctccat
    11161 ctggatatta tacagcagct gatgcagctc ccaataatgt aaaacttgaa ataagagcta
    11221 gagcaagtaa tctatgtttt ttcgttttca ttttattttt tctttcaaaa aaatcacacc
    11281 ttgagcaaca atgcaacaaa ataaatcctc ctctctcttt tattgaaacc gctttct
//
LOCUS       DAVLAQ010000058        11133 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000058 DAVLAQ010000000
VERSION     DAVLAQ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.058"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..796
                     /locus_tag="VXB71_001680"
     CDS             <1..796
                     /locus_tag="VXB71_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0451763.1"
                     /translation="LQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKIL
                     HYHKQKFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNF
                     KPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKT
                     AESVNQALTLLLGEHHILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHN
                     RLIRRWLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(825..2039)
                     /locus_tag="VXB71_001681"
     CDS             complement(825..2039)
                     /locus_tag="VXB71_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0451764.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(2195..2489)
                     /locus_tag="VXB71_001682"
                     /pseudo
     CDS             complement(2195..2489)
                     /locus_tag="VXB71_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2651..3103
                     /locus_tag="VXB71_001683"
     CDS             2651..3103
                     /locus_tag="VXB71_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0451765.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(3138..4526)
                     /locus_tag="VXB71_001684"
     CDS             complement(3138..4526)
                     /locus_tag="VXB71_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0451766.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            4592..5554
                     /locus_tag="VXB71_001685"
     CDS             4592..5554
                     /locus_tag="VXB71_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0451767.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(5760..6770)
                     /gene="ccpA"
                     /locus_tag="VXB71_001686"
     CDS             complement(5760..6770)
                     /gene="ccpA"
                     /locus_tag="VXB71_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0451768.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(7194..7793)
                     /locus_tag="VXB71_001687"
     CDS             complement(7194..7793)
                     /locus_tag="VXB71_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0451769.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7794..8891)
                     /locus_tag="VXB71_001688"
     CDS             complement(7794..8891)
                     /locus_tag="VXB71_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0451770.1"
                     /translation="MLERLKSIDYMYWASLIFMIFPILPVVTGEIPSWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8891..9628)
                     /locus_tag="VXB71_001689"
     CDS             complement(8891..9628)
                     /locus_tag="VXB71_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451771.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHTPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHFVRGVDMPLGSWIGAAFLLIVGSVAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYILVFSAVLFGLTIYLQGHKENA"
     gene            complement(9630..10514)
                     /locus_tag="VXB71_001690"
     CDS             complement(9630..10514)
                     /locus_tag="VXB71_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451772.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(10501..10695)
                     /locus_tag="VXB71_001691"
     CDS             complement(10501..10695)
                     /locus_tag="VXB71_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451773.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(10692..10823)
                     /locus_tag="VXB71_001692"
     CDS             complement(10692..10823)
                     /locus_tag="VXB71_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEV0451774.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKEFEE"
BASE COUNT         3406 a         2530 c         2044 g         3153 t
ORIGIN      
        1 tttacaacaa gtgagaaaag ggctatacaa aaaggtctat tctgccgatt acgcacaaac
       61 tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta attttaacaa aggaaatcag
      121 agagaagatc ttacactatc ataagcaaaa attttcgcct gaaatgatgg ttaacaagaa
      181 gcaagtgaaa gttggtattt caaccatcta ctactggttt cataatggtc atttaggatt
      241 gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt gtcaagaagc aagctagtcc
      301 gaactttaag ccggcaggta aatctatcga agaacgtcct gacgttatta atcttcgctt
      361 ggaaaatggt cattatgaaa ttgataccgt cctactgact aagataaaaa attattgcct
      421 gttagtctta accgaccggc ggagcagaca ccaaattata aggttaattc caaataaaac
      481 tgctgaatct gtcaatcagg cgcttacgtt actattaggg gagcatcata ttctgtccat
      541 tactgcagat aatggttcgg agttcaaacg attgtctgag gtatttcctg aggaacatat
      601 ctactacgca catgcttact cttcatggga gagaggttca aatgaaaatc ataatcgatt
      661 aattcggaga tggttaccta aaggaaccaa gaaaacgact ccgaaagaag tagcttttat
      721 cgaaaattgg attaacaact accctaaaaa atgcttggac tacaagtcgc caagtgaatt
      781 tcttttgggt ggctaacttc aacttgaaat ttgggatgca agccctatct acgatactgt
      841 ttcaagaaac gagtcatctt ttcttggatt tgggctaact catcaacacg aggaaggtaa
      901 acgatacgga agtggtctgg ttcctgccag ttaaagcctc gaccatgaac caagagaacc
      961 ttttcctgct tcaagaaatc aaggacaaac tgctcatcat catcgatacg gtacatattg
     1021 cggtcgattt ttgggaagat atagagcccc gccttgggtt taacggcaga caaacctgga
     1081 atatcttgaa tggcattata gatgaaattt ctttgctcgt agattcgtcc accaggaaga
     1141 agcaattcat cgactgattg gtgacccccc aaggaagttt gtacgacttg ttgggccaaa
     1201 acgttagagc aaaggcgcat attggacagc atattgagcc cttcgatata gcccttaaca
     1261 tgagtcttag ggccagacaa gaccatccaa cccacacgga aacctgctat gcggtgggat
     1321 tttgacagac cattcatgct gacacagaag acatctggtg ccaagctcgc cacaggcgta
     1381 tgcacatgtc cgtccattac catgcggtca tagatttcat ccgcaaagat aatcaaatcg
     1441 ttttgacggg caatctcaat aatctccagc aagagttcct taggataaag ggctccagtt
     1501 gggttatttg gattgataag gacaattgcc ttggtattgg aagtgatttt tgacttgata
     1561 tcgtcaatat ctgggtacca ttccacagct tcatcacaga tatagtgaac ggcatttcct
     1621 ccagctaggc tgacagccgc cgtccataga ggatagtctg gcattggcac taagacctca
     1681 tccccattgt ccaaaagccc ctgcatggac atgacaatca actcactgac accatttcca
     1741 aggtaaatat catcaatatc tacgtttggg aatttcttca gctggcaata ctgcatgatg
     1801 gccttacggg ctgagaaaat ccctttggag tcagaatagc cttcactatc acgcgcattc
     1861 ataatcaagt catgaatgac ctcgtctggc gctgtaaagc caaattctgc tggatttcct
     1921 gtattcagac gtaaaatctt ttctccattc gctcgcatcc gcatggcttc ttccaataca
     1981 ggaccacgga tatcataagc aacatgctct aacttactag acttgttata ttctttcatc
     2041 ttgtttcctc aattcatcag gatagtaaca ttataccact agaaagagaa tgcgacaagt
     2101 ttactgaaat gtgttactag tttcgtatag aagaaaaacc ttgctaaagg cgaggttaag
     2161 aacgtagaga tagcaggtat tttgcaaaga cacatcacat accaaaagat aaacctagaa
     2221 aaaagcaagc ctagaaagga gtcataaaga agattaaaca tgaggaaaag cccccatatc
     2281 atcaagtaat cccaacgccc acttcgtttt gcaactagaa ataagattag atggtagagt
     2341 acatgaaaaa ctaaaaatcc aataaaactt ggataaagaa gcggtaccag actctctaat
     2401 tgacagatca tgatcacttc taccaagact gaaactagga taattccata ataaaggaaa
     2461 tttgattttt gaaaagagtt tttcatcatt ctcccttcct tcacttcttt cctgctatcc
     2521 tttcttttat tttatcatat atttatatag agtttaagcc ctaatattct tttgaaaaat
     2581 actttttttg ctttacttct atagtgaaaa ggtttacaat tatagtaaga aaatttcagg
     2641 aggtttcatt atggcacaac gttaccaaaa tatcatggtc gcaatcgatg gttctaagga
     2701 agcggacttg gcttttgtca agggagttca ttctgctcta cgaaacgacg ctaaactcac
     2761 catcgcacat gtcattgaca cacgcgctct ccaaagcgta tccacctttg atgctgaagt
     2821 ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa gagtacgaaa aacgtgctaa
     2881 agatgctggg gtagcagatg ttcatatcgt cattgaaatg ggaaatccaa agaccctgct
     2941 agcacgtact attccagatg ccgaggaagt ggacctcatc ctcgttggcg caactggtct
     3001 caacgccttt gaacgcctct tggtcggctc ttcatctgaa tacatactcc gccatgctaa
     3061 ggtcgatttg ctggttgtga gagaacaaga aaaaacctta taatcacaaa gaaaaggagc
     3121 ccctagctcc tttttgttta cgatttattt ctctctttat ggcgttcgta agccttgagc
     3181 tggcgctgca gttccttttt aatagcaggt tctggagcat atttttcttc ccaattatct
     3241 ggttttaaga ttttatgggt cactggatca aaatgagcct tgccatctgg aaaaattttc
     3301 cccatattgg cctgatggac aatatcaaaa atacgttctg ggtccacccc catcaagaca
     3361 aaactgccgt aggtgaagta aagcgtgtca atcaaggcat ccacttgccc tatcaaatct
     3421 tgctgagcag gtgtcttctt ggctacttta cctgctgcct tatcaagggc ctgatgaagt
     3481 tgcgatacag cttgaccaaa atcttcttca gaaggactgg ctgatcgaac aaactccacc
     3541 aattcttcta ttttaaaacc agccctatgg gttgcaccct ctaaatccca agctcgaggt
     3601 tcttcttggg ttcgttcatc catcatgtgg tggaaggtct tgaccttatt gaaatgatag
     3661 tcacggctga caaaaacttt ttctgaagac aaaacaccaa aatgttccaa ggccttgtgg
     3721 atcccatctt gttgattgct agtggtaatg tgcttggcag cttccttgac actgctacta
     3781 ccatttccca tagcgaccga cataccgacg ccagccagca tttcaaggtc attatctgag
     3841 tcaccaaaag ccatgacttg gttgaggtca aagccatatt ctttcccaac tcggcgaatg
     3901 ccttctaatt tagaatttcc ctgattgatg acatccgatg caaaaggatt gctacgtgtc
     3961 aatttcaagt cttcaaaatc agctgccgcc ttctcagatt cttctggtgt catcagcatc
     4021 aaaacttggt aaataggttg attcatcagg tgaagcaggt cctcttcctt ttggggaaca
     4081 accttgctga ccatgcgatt aaaagactga ctcaccgtcc gagttaaaac agagggaacg
     4141 aagcgactaa ttcgttggga aaaagaaccc agaccaaagg acatgatttt agaacccaac
     4201 atggcatcct tggtccctaa ggcaatctcc gtgccctctt ttttagcata gctaattaga
     4261 tggcgcaaat gtaacttgga aatagggctc gtgaacaaga ctctgtcttt actaaagata
     4321 tactggccat tataggttac cgcaaaatcc agatccaaat cgtccatcaa ttccttaaca
     4381 aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc cttgttcttt gacaatctta
     4441 atcgcatcct tagtggattt caaaacactc ttgcgattgt tgaccaaggt tccatcgata
     4501 tcaaaaaaaa cagctttgac ttccatccta tcccaatctc cccttttgtg atacaatgat
     4561 tataccacat ttcagaaaga gtgagtaaat catgcctaag aaaatccttg ttttacatac
     4621 gggtggaact atttccatgc aggccgatgc ttctggcgct gttgtgacga gttcagataa
     4681 tcccatgaac catgtgtcca acccacttga aggaatccaa gtccacgcct tggacttttt
     4741 taaccttcca agtccccata tcaaacccaa acatatgctg gtcctctacc agaaaattaa
     4801 agaggaagca gataactacg atggagtggt gatcacacac ggaaccgata ctttagagga
     4861 aacagcctat ttccttgata ccatggaagt tccccatatg cctatcgttc taacaggagc
     4921 catgcgtagc tccaatgaac tcggtagtga tggtgtttat aattacctaa gtgctttacg
     4981 agtggccagc gatgacaggg ctgctgacaa aggagttttg gtcgttatga acgatgaaat
     5041 ccacgctgcc aagtatgtca ccaaaacaca tacgactaat gtcagcacct tccagactcc
     5101 aacacatggc ccccttggtc tcatcatgaa acaggaaatc ctctacttca aaacagctga
     5161 acctcgtgtt cgctttgacc ttgatcacat acaaggttta gtccctatca tctcggctta
     5221 tgctggtatg acagatgagc tgattgatat gctggattta gaacacttgg acggtttgat
     5281 tatccaagcc ttcggagctg gtaatattcc caaagaaacg gctcaaaaat tagaaagcct
     5341 tctgcaaaaa ggaattccag tcgctctggt atcacgatgc tttaacggta ttgccgagcc
     5401 tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa gcaggcgttt tctttgttaa
     5461 agaactcaac gcccaaaaag ctcgcttgaa actcctcatc gccctcaatg ccggactaac
     5521 aggacaggct ttgaaagact atatggaagg ctaatactct tcgaaaatct ctgcaaacca
     5581 cgtcacgtcg ccttaccgta tgtatggtta ctgacttcgt cagtttcatc tacaacctca
     5641 aaacagtgtg ttgcgcagcc tttaaccagc cgcctagtcc gctctatggt attcattaag
     5701 tcaacatctc ttgtttaaga gcacaaaatc aggaaatctt ctcgattccc tgattttttc
     5761 tatttacgtt ttcgtgttga gctacgttct gtcaaaccat gaggtaagag aacttcacgt
     5821 tcttccaact cttccttatg cataatcttg gtcaacatac gcatactaat ggcaccaagg
     5881 tcataaagag gttgggcaat cgttgtcaag tttggacggg taaagcgtga gatttgtgaa
     5941 tcatcactag taataatttc aaaatcttct ggcacagaaa cacccttatc agccaaaccg
     6001 ttcaagactc ctgctgccaa ctcatcacct gtcacaactg ctgcagttgc atttgatgaa
     6061 atcaaacgct ctgctaaggc gtaaccatca tcatagctat atttagattc aaataccaaa
     6121 ccctcactat aagtgattcc tgcttttttc aaggtttcct tgtagccaac taaacgaacc
     6181 ttaccattga tgtcatccac tagcggaccg ctaacgaaag caatacgctc attttcttta
     6241 acaaggtaac tcactgcatc aattgttgct tgcttatagt caatattgac acttggcaac
     6301 tggtgctcaa catcgacagt tcctgcgaga acaatcggag tacgtgaacg cgaaaattct
     6361 gagcgaattt tatctgtcaa gtgataaccc atatagataa tgccatctac ctgctttgaa
     6421 aagagggtat tgacaacaga aacttctttc tcgttatctt catcgctatt agctaggaca
     6481 atattgtact tgtacatttc tgcaatatca tcaatcccct tagccaaact cgaaaaataa
     6541 ccattggtaa tatttggaat cacgacaccg acagtggttg tctttttact tgcaagacca
     6601 cgcgcaactg catttggacg ataatccaaa cgatcaatta cctctagcac ttttttacgg
     6661 gtattctctt ttacattttt attgccattg accacacggc tgaccgtcgc catggaaaca
     6721 cctgcttcac gagcgacatc ataaatggtt actgtatcat ctgcattcat tccttttcct
     6781 gtcctttcta tctcacacat tcttttacaa gtagaggtgc tgattgaagc tctatatcta
     6841 cttacaaaag tgaagatgtg aaaatttcgt tttcatattt ctacttattc cattctatca
     6901 ctaattgtaa acactttcaa gtgttttttg aagattgatt gaaaaaattt catagaaaac
     6961 ctaggtttag ctccttgcta ccaccttaga ctaaacaaaa aggaggaaac taagccctcc
     7021 taaagttata gtaaaatgaa ataagaacag gataaatcga tcaggacagt caaatcgatt
     7081 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact ataggtattg
     7141 ttccattcac taccgtcaat tttagcacat agtcttcata aaatattata tcatcataac
     7201 caaccagatt cttttgcgat attagctgcc tctgttcgat taccagcatc cagttttgaa
     7261 agaatattgg tgacatagtt tcgaatagtt ccgtttgaga ggtaaagctg atctgcgatt
     7321 tcttggttgg ataagccccg ggcgattccc tttaagacag caatctcttg ttctgtcaac
     7381 ggattgggac gggtcatcac cacttccatc aattcaggcg aatactcctt gcgtccttcg
     7441 aggacggtgt gcaaggtttg catgaggtct gcaatgcttc gttcctttaa tacataagca
     7501 tctactccag ccttgaccgc acgttcaaaa taccctgggc gcttgaaggt cgtcactaca
     7561 accacctttg tttcgagctt ttctgctcgt atccactcca agacttcgag tcctgtctta
     7621 acaggcattt ctacgtcaag gatggcgata tctacagact ccttttctaa tagttgaatt
     7681 gcttcttgac cattcttggc ttgtaagaca gactctacat ctgcttgaaa ggcaagcaac
     7741 tggcacatgg catctcgcaa catactttga tcttctgcga ctaatacttt catctacttt
     7801 ctctccttat aaggtagtcg aacttgcact tccgttggat gtttctgact gattacactt
     7861 acttctcctg aaaatggaga aacacgatct cggactgtat ggagctcatc tccttttaga
     7921 aaagcaaagc cgcagccatc atcacttact gttaaaatga gttctttctc tgcccgttct
     7981 aatttcaggt aggccttcga cgctttggca tgtttgataa tattggtcac caactcaagc
     8041 aaaatcatgg aagccgttga ctccaattct tgagtaagac tagcagtatc tagttggtta
     8101 tccgtttcca cctcaattcc agcaatttct aacatctttt tcacagtctc tagttcggat
     8161 gtcaaagttc tagacttaag attttccaca atggttcgca cttcattcat ggaatcctta
     8221 ctgatctggt gaatttcttt taattccttt tccacctgtg gataagcctc catctgaaat
     8281 aactgcaagg ctaaatctgt cttgacactc aacatagcaa aggtatgtcc caagctatca
     8341 tgcaaatcct gaccgatacg actgcgttca ttttcagcaa gcaatagatt tatctgggca
     8401 ttttgcttga cctgagcttc tttcaaatcc tccacaatac gaatccgaac caagccaaaa
     8461 gtcattaaat cgacaaaagc aagaattaca agtagataga atagaaactc aacttcgatt
     8521 ctctgaaaaa tcaacagttg gcccacaaca aggacttgag caagaagaaa agtccagaca
     8581 tgtaaagact ttaaaccacc tacgctgaaa tgataactta agagattgga taggaaaaag
     8641 aaaaaccaga tataattaac agcaacaaag gcagtattcc caactacata agtcagcatg
     8701 aggccccaat atagccaaga taggcgctgg ctcttagttg ttaaaacacc caaatacgcc
     8761 actacaaata gaatatcaat caataaatgc cagctaggaa tctccccagt cactacaggt
     8821 aggatgggga aaatcataaa aattaaactg gcccaataca tatagtctat gctttttagt
     8881 ctttcaagca ttaagcattc tccttatgac cttgaagata aatggtcaaa ccaaacaaaa
     8941 ctgctgaaaa aacaagtata taaactgtgg ctgatagatt gatgccaccc tcgtttaaga
     9001 aggttttgag caactccatc aactgataag ttggtaggca cttcccgatt gcttgcatcc
     9061 agtctggaaa taaagagatg ggcatccaga gtccgcctaa aacagccaag cctagataga
     9121 gaagattgcc cacgacagac atcaactgac tagaaggcaa gagtgtcaag gtcaagccaa
     9181 gcgctacaaa ggcaacactt cctactatta gcaagaacgc agccccaatc cagcttccta
     9241 gaggcatatc cacacctctt acaaaatgcc caactgagaa aacaaccaga attgatacca
     9301 aataatcaac catcatactt gttatctttg atagataata ttctaccata tttacagggg
     9361 tatggcgcaa tgttttctgc cagttgttga ttttatcagt atgtaagaca gctgggaatg
     9421 aaaacatagc tgtcgacatc atggaaaagg ctgtcatgga gatgaggtaa tcacgcataa
     9481 aattcgcgag ttcacctggt gtgtcctgat agataccaga aaaaaataaa tagaaagccg
     9541 tcggcatccc taccgacaat agataataga ttaattgtcg tttggtcaat aaaaattcta
     9601 tcttactaag tgctatccat cgtttcatct tagttatctc ccttttgtgt ttcttcaaag
     9661 attgtattca acaaactacg attattaact tcgatttctt gcatcctaca tcctgcttgg
     9721 gctaatagtt cccagaaagc atctgcttct cgagtgacta cttgtagagc atcctgtttt
     9781 tgtgaccagt tttcaaccaa gttagactgc tcaatgactt ccttgtatgc cagaggaagg
     9841 ataaaatgct tttcaattcc ctcactacgc atagctagag gcgtcgtatc acgaatcaac
     9901 tctcccttat ttaaaaccaa aatccggtca gccgtatgct ctacctcttc aatataatga
     9961 gacgaataga gaatcgtgac tccttgcgct tttaggtccc gaacgatttc ccaaaagcgt
    10021 tgacgagttg aagtatccat ggcagcagtt ggttcatcta aaaagacaag ctttggtcgc
    10081 ccaatcaagg tcaagacaaa agagaagaga cgcttttgcc cgcctgacaa tttttctgcg
    10141 aattgctctt tttgttgctg gtcaaactgc aatagttgat cgatttcctg atcgctcaag
    10201 gaatttggat agatacgttg aaagaaagca atcaactctt tgacctttaa tttctgaacg
    10261 atgacatttt cttgaggcag ataacctcta atatagtcta actgagaact cgtcactgac
    10321 aagccttgga tggatacttg accgcttgtg accagtttat ctccaagcag acagtccaag
    10381 agtgtggtct tcccagcacc attgggccca atcaaggcga cgcattcacc ttcagctacc
    10441 tcaaaggaaa tacccttcaa aatagccttg cccttgatgt ttttatttag gctttctacc
    10501 ttaatcatat tcatgatatt ctcctttcaa ccactccatt ctcataagga aaacgacgaa
    10561 aatcataaat ccaaacccca aagcaccacg aatgaattgg cgaagcaagg tttggtcaaa
    10621 ccaacctgta aacatttcca ctaaccatac caagagtgac aggccgataa agaaatagat
    10681 gatccctctc ttcattcctc aaactccttt ttcacatctc cgactaattt caaaccttct
    10741 ctaacaagcc aagacatcat tccaaagcca gcaaagagct cccaaggaaa atgatagaaa
    10801 ctctcatcca atcccgaaaa catgagttag gtcataactc ctgctactac taaactcact
    10861 gcgataatca ttttatttct catctcttct tcctccattt catactacaa ttatagtctt
    10921 ttgaaatcag aggagacaga agcttctgtc actagaaaat atgacaaatg tcataaaaaa
    10981 ttctgttcaa aacaagcaag atacactata caataaaaca caatcagaaa aatctaaggc
    11041 aacttcctca aaagagatat caaacccaat tcacaccata atgtaaacta atacttattt
    11101 aaaatcaaaa agagtagaaa tttttatcag aca
//
LOCUS       DAVLAQ010000059        11127 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000059 DAVLAQ010000000
VERSION     DAVLAQ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.059"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..975
                     /locus_tag="VXB71_001693"
                     /pseudo
     CDS             1..975
                     /locus_tag="VXB71_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1001..1645
                     /locus_tag="VXB71_001694"
     CDS             1001..1645
                     /locus_tag="VXB71_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0451775.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1687..3675)
                     /locus_tag="VXB71_001695"
     CDS             complement(1687..3675)
                     /locus_tag="VXB71_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0451776.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFTKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3677..4435)
                     /locus_tag="VXB71_001696"
     CDS             complement(3677..4435)
                     /locus_tag="VXB71_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451777.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4863..5054
                     /locus_tag="VXB71_001697"
     CDS             4863..5054
                     /locus_tag="VXB71_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451778.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5408..5680)
                     /locus_tag="VXB71_001698"
     CDS             complement(5408..5680)
                     /locus_tag="VXB71_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0451779.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5739..6188)
                     /locus_tag="VXB71_001699"
     CDS             complement(5739..6188)
                     /locus_tag="VXB71_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0451780.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(6175..8304)
                     /locus_tag="VXB71_001700"
     CDS             complement(6175..8304)
                     /locus_tag="VXB71_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0451781.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8348..8431
                     /locus_tag="VXB71_001701"
                     /pseudo
     CDS             8348..8431
                     /locus_tag="VXB71_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8420..8560
                     /locus_tag="VXB71_001702"
     CDS             8420..8560
                     /locus_tag="VXB71_001702"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451782.1"
                     /translation="MDKTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNRTTVR
                     RS"
     gene            8806..9711
                     /locus_tag="VXB71_001703"
     CDS             8806..9711
                     /locus_tag="VXB71_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0451783.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            9708..10523
                     /locus_tag="VXB71_001704"
     CDS             9708..10523
                     /locus_tag="VXB71_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0451784.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(10653..>11127)
                     /locus_tag="VXB71_001705"
     CDS             complement(10653..>11127)
                     /locus_tag="VXB71_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0451785.1"
                     /translation="LILLDGGYLDLDKILPLDTELEETKNYIKSQIISDLDVLTSKEK
                     SEAKHWSENMEKAVRQSYHWNVEYNRYELAINYENIEAILRLRRKIQAFKREVGDTLF
                     ISPRYPNEATWREEALKELPDYFDTIFLENFGHELYTQAPKEIASLMNEWLAYFL"
BASE COUNT         3328 a         2331 c         2148 g         3320 t
ORIGIN      
        1 aaagccaaac atttgacaat cgatagccgt cgcttaatcg aaagatggaa aaaagaagga
       61 aaatcaaata gagaaattgc ctctctactt ggaaaagctc ctcaaactat ccacactgaa
      121 atcaagcgta ggacagtccg acaatgtctt ggaaaagggc gcttcaaaga ggtttattct
      181 gccgactatg ctcaacagtc ttatgaaaat aatcgcaagc actcggtcaa gagatcaagc
      241 gtgaccaagg aactaaagga aaagattctc cactatcata accaaaaatt ttcgcctgaa
      301 atgatggtta tggctaaagg ggttaacgtg ggaatttcaa ccatttacta ttggattcat
      361 catggaaaat tggggttaag caagcaggat ctgctttacc ctagaaaagg aaaagcgctt
      421 aagaaacagg ctagcaccaa ctttaaacct gctggtcaat ccatcgaaca gcggcctgaa
      481 gctatcaatc ttcgcttgga gaatgggcat tatgagattg atacggttct acttacgaga
      541 tcgaaaaact actgcttgct tgtcttgacg gatcgaaaga gtagacatca gatcatccga
      601 ttgattccaa ataaaagtgc tgaggtggtc aatcaggctc taaaactcat cttaaaacaa
      661 cacaagattc tttccatcac ggcagataat ggaacggaat tcaatcgctt gtttgatata
      721 ttttctgagg agcacatcta ttatgcgcac ccctatgcct cttgggaaag gggaactaat
      781 gagaatcaca acaggctcat tcgtagatag ttacctaagg gaaccaagaa aatgactccc
      841 aaagaagtcg cattcatcga aaagtggatt aacaactatc ctaaaaaatg cttggactac
      901 aagtcaccca gagaagactt ctggatggct aacttgaact tgaaatttag cgtcagaaac
      961 aaatcacgaa attgattcaa attttgcagg tcgtttaaat atcctgcgtg cgggtgttct
     1021 tgatgctaac gatggaatta tttccattgc tggtgtggtt atcggagttg ccagtgccac
     1081 gaccaatatc tggattatct ttttatcagg ttttacggct atcttagctg gtgccttttc
     1141 aatggctggt ggagaatatg tatccgtttc aactccaaaa gataccgagg aagctgccgt
     1201 ttcgcgagaa aaactcttgc tagaccaaga tagggaacta gccaaaaaat ccctctatgc
     1261 tgcttatatc caaaatggag aattcaaaac ttctgcccaa ctcttgacca ataagatctt
     1321 tcttaaaaat ccactcaagg ctctggtaga ggaaaaatat gggattgagt atgaagaatt
     1381 taccaatcct tggcacgctg ccatttctag cttcgttgcc tttttcctta gaagtttgcc
     1441 tccaatgctg tcagtgacca tttttccaag tgattaccgc atccctgcta ccgtccttat
     1501 tgtcggtgtg gcccttcttc tcactggtta cacaagtgct agacttggaa aagccccaac
     1561 caaaacagct atgattcgga accttgctat tggtctcttg accatgggag ttaccttcct
     1621 gctcgaacaa cttttcagca tttagaatac aagaaatacc tcgattttga agtcgaggta
     1681 tcttttttac atttgcacaa tcttgcgata acttcttgaa gtaatcatga aaatcagcac
     1741 ataggcgatg aggaagatag cgcagataga caaggtcaca atcaacatca tagtcgtatc
     1801 cagtacacca atcactttta aaatcaggct aagcatatgg taggcaaagg cgagatgtat
     1861 gaaggcaaag agcaaaggaa ggaagaaaac agttaaaacc tgtttgttga tggtttgctt
     1921 gatttgcttt tggtccaaac cgactttctg caagataata aagcgttcac ggtcttcgta
     1981 gccttcagaa atttgtttgt agtagatgac cagaacagtt ccgaccataa agataatgga
     2041 taggaaaata ccgataaaga agacaccacc aaagagggca ctcatctgag aactagcatc
     2101 tgctagattg ctaccataaa catagctacc ttctgtgtct aattgagcat taaattgatt
     2161 gaggtagttt tcatactcct cagcgacctt gagttgttct tcttcgctgg catctacatt
     2221 cataccaccg taaaactgat tatagatagc cgaatctggg aattgatcca aaaaggcttg
     2281 taaatcagga acaacaaggt aattgtaatc agtagtcaag atattaaact tatttggaac
     2341 atggttgaca ataaaatctt tagtaaattc ttctttgaca gaaaattgat gatcatttag
     2401 agttagagct ttctgtcctt tcagtccgtc atttttggca aagagaccga cctcatttcc
     2461 tgatagagac agtttttgac cagtcatatt ttcataatct ttttggtcaa ataccatgaa
     2521 aactgttttt ggttggacac ggttttgtcc tttttcaaaa atagttaact tggttccttc
     2581 ttgattcgca acagcaaagt aagtgtaacg aaatacttct ttttctttaa tcttataacc
     2641 tttgtcactt gcaaactggc tcaagagttt gtccaagtct tctttttcaa cattttgccc
     2701 tgaaacccca aaatcatgag gatttagaac ttttttaaag ctttctgagg aattgaaaat
     2761 gcttgtcgct gctgacatgg ttaccaaaac cattgttgac aagatagcga tggtggctag
     2821 tccaactgca tttttcttca tacggaaaat caagttagaa acagatatga ggttatttgg
     2881 ttggtaatag tatttcttat ttttctttaa gatttggagg aaaacggtaa tccctgcatt
     2941 aaacaagaga taagtcccaa agataaccag taaaacagct atgaagaagg ttgttaaggc
     3001 tgtaagagga tcttttaccg taagggcaag ataatagcca attcctaaac ttatggaacc
     3061 aagaatggtt tggagaggaa ggaagcgacc ttttttctct ccactagctt tctcacgaga
     3121 gagctggagg gcattcatac gggcgattcg aagggcattc aggaacatga ggcctaggaa
     3181 aatcaaaccg aagacaacaa gcactgtaat gacaactttc gtctggaagg tagcaaccag
     3241 ctcaaccttc aatttcatta gtttgagcag gaaagcgaaa attaacttgt caaacaaggc
     3301 tccaataccg atacccgctc caacagttag aatcccaaat accactaact ccttaaaggt
     3361 catactgata agatgacgct tctccaagcc caacatgcca taaattccta gttccttgga
     3421 acggttcttc atgacaaaac tattggcata gagaacgata atggctgacg caagggtgac
     3481 gacaaacata ccaaatccaa gtgtagcctg aatggttgtt cctccacgga tttccgcaat
     3541 cttaggattg aaggttagag agtaaaagag ataggtgaca gtgactgcca agagaacagc
     3601 cagcgcaaaa ggatagtaga gtttgcggtt tttaatcaag ttcgataccg ctaacttatt
     3661 ggttaatcga aacatactaa ttcacctcgc ttgccatgac agtcaaggta tcagagattt
     3721 cttggaacat ctgacgttct gtcttctctc cacggtagat ttgattgtaa agaatgccgt
     3781 ctttgataaa gagtacacgt ttagctctgc tagctgctgc tgttgagtgg gttaccatga
     3841 gaatggtttg gccgcgctca ttgatttcat caaagacatc aagtaaggct gcagatgact
     3901 tggagtcaag agctcctgtc ggttcgtccg caaggagaat ttcaggttct gtgatgatgg
     3961 cgcgggctac tgctacacgc tgtttctgac caccagaaat ctcgtaaggg tacttctctt
     4021 gtaattggtt tattcccaga ttctcagctg tcaccaccaa tttcttcatc atctctgtaa
     4081 taggtcttct tgacaagaca agcggaagca agatattgtc ctttacagat agagtatcta
     4141 gcaagttaaa gtcttggaag acaaagccca acttttcacg acggaagcta gaggcctgtg
     4201 aatttttaat ggttgcggtg tcagttccat tcaagtaaac ctgaccacga cttggtttat
     4261 ccagcatagc tagaatattg agaagagttg atttaccaga accagactca cccatgatgg
     4321 caacgtagtc acccttttcg acggtaaagt gaatatcctt gagggcttct acttggttgc
     4381 cctgaaaacg tgttttataa attttttgaa cgtgttttac atctaaaagt gtcatgagaa
     4441 tctcctttct taatatccca tcaaatgaaa tgtagcttgc atcatagtgc atcccagctg
     4501 aacgcgctca atttctttgt gacttggttt tctagttttc ttatgtaaga tttgtttcat
     4561 gatgttactc ctttgttctt tatgagtcta gtttacatca aaaaaagacc gcttgccata
     4621 acctaacctt acaaaagaga ctttaatctt acatttttgt aagattgggt gaaatataag
     4681 caaaattact tagaaaatga tttgatttcc tatttttaaa gttgtaaaat ataagtgtga
     4741 aaaggcttac tttgaaaagg aggaagcggg aactaacatt ttagtaaggt tacctagata
     4801 acataccatt caatttaaca cttgcaagtc gttcaaccta taaggaaaga aggtgcgctt
     4861 taatgaaaca caaagaacat atactcatcg gacttctcta tctgctctct ccattcatcg
     4921 gtcagctctt agttgaacac acacacttta tcggtacaga atttaccggc actgcttatg
     4981 ttatttgctg gttatcagtt gttatcagca tccaccattt ttccaaaaat gtattgtctc
     5041 agcagcaaaa atagattaaa aaactgagtt taaattactg cttttataat aaaatgaaat
     5101 aagaacagga caaatcgatc aggatagtca aatcgatttc taacaatgtt ttagaagtag
     5161 aggtgtccta ttctagttcc aatccactat agtttgtgga tgaagctggc gaaatattat
     5221 taatactatt caaaaatcaa agtgcaaact atgtcaactt cacattgccg actaaattac
     5281 agcctgtggc tggcttccta gtttgcactt tgatttttat tgagtataaa agtaaaaaag
     5341 ctttaaatca agcagtttag actattgatt taaagctttt tgcttattcc aaatcttctg
     5401 tagaacctca ccaaaaccag ccttcattgt cgtcaatggc ttgggcttct ttgcgtttac
     5461 gtgggcctgt tccgtacatt tctgcttcga tttcttcctt ggtaggcatg atagaagcta
     5521 ggatgatata gataatcacg ccaagtccaa agtttgcaac tgtaaaaata gcaaacaaga
     5581 aacgaactag ggtaacatca aaattccact tgtctgacag acctgccaga actcctgaaa
     5641 tcatgcgatt gcgtctcatt ttataaaatt tactgttcat gatatttcct ctttctgcta
     5701 ggttagacat agtatatcac ggggaggctc ggctttcatc agtcctcagg ctgatttatc
     5761 agaagcaatt tacctcgaca aagtccacag cgatagcgtt tggtatcaat cctacgcttg
     5821 cgctgatacc tttgctggca ggattgacaa cgataaagct tgagtggttt agagttacta
     5881 ttgggcaagg atggtacaaa ccgtaatcca tccactgctt tcaaaagttc cttaaaatcc
     5941 cgatccttgt gttgatagcc cttcccttgg aaataaaggt gataatgaca gagttcatgt
     6001 cggacaattt tcctaaaaac ctccataccc agtttctgat aaaccttggg attaaaatcc
     6061 agatgcccat ctttggggaa aaatcgccca cctgtcgaac gtagacgcct attccactgg
     6121 acatgatgga taaaagctct cccgaagtct tctagtgaaa cctgcttgac ataatcagtc
     6181 agtttcattt ggagcgagga gcgacagatt aactttttca cgttcagtat caattttctt
     6241 gacccaaacg gtcaccaaat ctccaactgc caccacttga ctagggtgtt tgataaactt
     6301 gcgactcata tgagaaatat gaatcaagcc gtcctcgtga atcccgatat caacgaaggc
     6361 accgaagtca acaacgttac gcacaacacc ttctagcttc tgacctacca ctaggtcttt
     6421 gatatctagg acatcttggc gaagcacagg tgcgtcaaag gaatcacgga aatctcgacc
     6481 tggtttgaga agatctgcaa tgatatcttt aagggtttct ggaccgaggt ctagctcttg
     6541 agccatttcc ttgactgaaa gcgacttgag tttgctttgg gcctcttcat tcagatcctt
     6601 aatgtccaag catttgaaga gttccttaac ggcagcgtaa ttttctgggt gaactcctgt
     6661 attatcaagg atattgctac tttcagggat acggaggaaa ccagcagcct gttcaaaagc
     6721 cttggccccc aaacgaggaa ctttcttgat ttgggagcgt gaagtgattt ttccctcttc
     6781 ctcacggtat ttgacgatat tttcagaaat ggttttattg agtccagcta cgtgtgaaag
     6841 aagagctggg ctagctgtat tgacattgac accaacttgg ttaaccactg tatcgacaac
     6901 aaagtccaga ctctcagata gtttcttctg actgacatcg tgttggtatt gaccgacacc
     6961 aattgactta ggatcgattt tgaccaattc cgcaagagga tcttgcaaac gacgggcgat
     7021 agaaatggca gagcgttttt caacggtcaa gtctggaaac tcctgacgag caagttcgct
     7081 ggcagaatag acagaagcac cactttcatt aacgataaca tagctgactt cagggaaatc
     7141 tttcagaact tccgctacaa aagcttcact ttcacgactg gccgttccat ttccaatggc
     7201 aataatctct acaccgtatt gaccaattaa atctgctaaa tctttcttgg cttcttcgat
     7261 ttgacgagct gatgctggtt taacaggata aataacctga gttgtcagca tttttcctgt
     7321 tgcatccacg acagctagct tggcacctgt acgaaaggct gggtcaaacc caagaaccac
     7381 gcgccctttc agtggagcaa ccaagaggag attgcgcaga ttgtcagaaa aaagttggat
     7441 agctccctct tcagctttct cagttaattc tgtccgaata cgacgctcaa tagcaggcaa
     7501 gacctttttc ttaacggatt gctgaacaac ttcatcaata taagcatttt tcaccttgaa
     7561 acgagtagca aagaaggcaa gaatacggtc cgtcgcatgt tcaaaaccga tcttcaagac
     7621 accaagtttc tccccacgat tgagagccaa ggtacgatag ccttgcatag ttccaactgt
     7681 ctctgaaaaa tcataataaa tctgaaaaac ctgcttttca tcaagacttt catccttggc
     7741 ttgagaagtg agtttagagt gtctcagcac ttcctgataa gtcatagaac gcaaggtcac
     7801 atcttccgat aaggcttcga ccaaaatatc aactgcaccg gtcaaggctt ccttgccagt
     7861 cgcaaatcct tcacagacga acttttcagc ttctttctct aagtcaacta tattctgcaa
     7921 aatcaaacga gcaagaggaa agagtccagc ttcacgggca atggttgcct tggtacgacg
     7981 cttttcctta taaggaagat agagttcttc aacgtctgct aatttttcgg caactaagat
     8041 agcttcttcc aattccttgg tcaacttacc ttgttcttga atcttagcta agacagcttc
     8101 cttacggtca ttgagatttg tcagactttt atccaaatca ataatagcct taatcgccac
     8161 ctcatccaga ctaccagtca tgtccttgcg ataacgcgcg ataaagggaa tagtcgcccc
     8221 ttcagctgtc aaacttagaa cggtatcaat ttgctttaac gtcactccca aatcctgaga
     8281 gattttttca tattttttat ccataaatct attataccac aagctggaag gctttctcca
     8341 atccttttca tactcaataa aaatcaaaaa gcaaactagg aagctagccg taggctgctc
     8401 aaaatactgt tttgaggttg tggataagac tgacgaagtc agctcaaaac actgttttga
     8461 ggttgtggat agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac
     8521 tgacgaagtc agtaaccgta ctacggtaag gcgaagctga cgtggtttga agagattttc
     8581 gaagagtatc aactatcgaa aacaaattaa aaaactccct tttccgcaaa ataatagtat
     8641 aatagaggta gaatttagaa tcgaggtaca cctatggctg tcaaatttac aaaacgagac
     8701 gacttggaca agatgtttga agagtttgct aaactccctg atttgaaaca agttactttc
     8761 cctgatgaca aagagaaaaa agtcaaagca gaaaagaaaa actagatgac tgcttttcaa
     8821 caactcccat ctagtgtact tcaaactgga gccatttttc tctccattat cattgaagcc
     8881 cttcccttcg ttctgatagg aagcattgtc tcagggctga ttgaagttta tatcacacct
     8941 gacaaggttt atcattttct ccctcgaaat cgttggggga gaatcttttt tgggaccttt
     9001 gtcggtatac ttttcccttc ttgtgaatgt ggaatcgtcc ccatcatcaa tcgttttctg
     9061 gaaaaaaagg ttccaagtta cacggccgtt ccttttcttg tgacagcacc tgttatcaat
     9121 cccattgttc tttttgcgac ctattctgcc tttggcaact ccttccatgt cgccctatta
     9181 cgagctctgg gttccattct tgtggctgta atactaggaa tttttctagg atttttctgg
     9241 caagaaccga ttcagaaaga aaatcgtctg gcttgtcatg agcatgattt ttcttacttg
     9301 agttctgcaa aaaaagtttt tcaagtcttt gtgcaggcca ttgatgaatt ttttgatacg
     9361 gggcgttatt tggtatttgg ctgcctcttt gcttctataa tacaggtcta cgttccgact
     9421 cggattctga cctctatcag tgcgacccct ctttttgcca tcctgctctt gatgatttta
     9481 gcctttcttc tttcgctctg tagtgaggcg gatgccttta taggtgcttc tcttctctcg
     9541 agtttcggtt tggcaccagt tctggccttt ctcgtcattg gtccaatgct ggatatcaaa
     9601 aatattctca tgatgaaaaa ttacttgaaa gcacgattta tcagtcactt cataacaatt
     9661 gtaactcttg tcgtcttagt ctattctctc ttgattggag tcatcctatg attcgatttt
     9721 tagttttagc tggctatttt gaactgacta tttacctcca tctgtcgggc aaactaaacc
     9781 agtacatcaa catgcactat tcctatctgg cctatatctc catggtgctt tcttttatct
     9841 tggctatcgt tcaattgtat atctggatga agcaagtcaa aacccacagt catctgaaca
     9901 gccgattggc caagatgacg agtatttctc ttctggctat tccacttgtc atcggcttaa
     9961 ctttcccaac tgttagcttg gattctcaga ctgtttcagc taaaggctat catttccctc
    10021 tatcggaagg aacgaatctg gctattcaga caagtgaagg gactacaagc caatatttga
    10081 aaccagatac tagttcttat ttttcaaaat cagcctatga aaaggaaatg cgaacggcgg
    10141 cggataaata cttatcccaa gacagcattc agatcactaa tgaaaactat atggaagtca
    10201 tggaggctat ctacgactat ccagatgagt ttgagggcaa gacaatccag tttacaggct
    10261 ttgtctataa cgaccccagt catgccaata gtcaatttct gttccgattc ggcattatcc
    10321 actgtatcgc agattctggt gtctatggat tgctgaccaa gggcaatacc cggcagtatg
    10381 aaaacaacac ttggatttca gccaaaggaa aactggtcaa tcactaccat aaagaactca
    10441 aacaaaacct tccaaccttg gaaatcgaca gctttaccaa agtcgataaa ccagaaaatc
    10501 cctatgtata tagagctttt taagaaaatc aagataaaaa cgaacaagtt ctcttctgaa
    10561 taacagaaaa agagcctgtt cgttttttgg ttatatgaaa attagtgact tgtagatttt
    10621 catcttatac catttccagc aatacaagta gctcatagaa aataagcgag ccactcattc
    10681 attagactag cgatttcttt aggtgcttga gtataaagct catggccaaa gttttctaaa
    10741 aaaatagtat caaaatagtc tggcaattct tttagggctt cctctctcca tgtagcttca
    10801 ttaggatagc gaggactaat aaacaaggta tctcccactt ctctcttaaa agcttgtatt
    10861 tttctccgta ggcggagtat cgcttctata ttttcataat ttatagccaa ctcatatcta
    10921 ttatactcaa cattccagtg ataggactgt cttacagctt tctccatatt ttctgaccaa
    10981 tgctttgctt cagatttttc tttagaagta agaacatcta agtccgaaat aatttgagat
    11041 ttgatataat ttttagtttc ctctaactct gtatccaaag gtaaaatctt atctaaatct
    11101 agatagccac catccaaaag aatcagt
//
LOCUS       DAVLAQ010000060        11025 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000060 DAVLAQ010000000
VERSION     DAVLAQ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.060"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            11..733
                     /locus_tag="VXB71_001706"
     CDS             11..733
                     /locus_tag="VXB71_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0451786.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            730..1578
                     /locus_tag="VXB71_001707"
     CDS             730..1578
                     /locus_tag="VXB71_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0451787.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1610..2539
                     /gene="psaA"
                     /locus_tag="VXB71_001708"
     CDS             1610..2539
                     /gene="psaA"
                     /locus_tag="VXB71_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0451788.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2662..3153
                     /gene="tpx"
                     /locus_tag="VXB71_001709"
     CDS             2662..3153
                     /gene="tpx"
                     /locus_tag="VXB71_001709"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0451789.1"
                     /translation="MVTFLGNPVSFTGKQLQGGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3249..5957)
                     /locus_tag="VXB71_001710"
     CDS             complement(3249..5957)
                     /locus_tag="VXB71_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0451790.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGIVVGETQIQFYWTYSLLALVLSWLASVLPVYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSETPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5959..6660)
                     /locus_tag="VXB71_001711"
     CDS             complement(5959..6660)
                     /locus_tag="VXB71_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451791.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6910..9321)
                     /locus_tag="VXB71_001712"
     CDS             complement(6910..9321)
                     /locus_tag="VXB71_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0451792.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAVRASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(9374..10066)
                     /locus_tag="VXB71_001713"
     CDS             complement(9374..10066)
                     /locus_tag="VXB71_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0451793.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10117..10407)
                     /locus_tag="VXB71_001714"
     CDS             complement(10117..10407)
                     /locus_tag="VXB71_001714"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451794.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            complement(10601..10981)
                     /locus_tag="VXB71_001715"
     CDS             complement(10601..10981)
                     /locus_tag="VXB71_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451795.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
BASE COUNT         3225 a         2530 c         2054 g         3216 t
ORIGIN      
        1 atacaagttt atgatacgta tcgaaaacct cagtgtctcc tacaaagaaa cgttggcact
       61 taaggatatt tcactagtgc tccatggacc aacaattacc ggcatcattg gtccaaacgg
      121 cgctgggaaa tcaacactat taaaaggtat gctgggaatt atcccacatc aaggtcaggc
      181 atttctcgat gacaaggaag ttaaaaaatc cttacaccga attgcctatg tcgaacaaaa
      241 aatcaatatc gactacaact ttcccatcaa ggtcaaggaa tgcgtctcgt taggactatt
      301 tccctctatt cctctctttc gaagtttaaa ggctaaacat tggaagaaag tgcaagaggc
      361 ccttgaaatc gtcggcctag ctgactacgc tgaacgtcaa attagtcaac tgtctggagg
      421 tcaattccag cgggtcttga ttgccagatg tttggtgcag gaagccgact atatcctctt
      481 ggatgaaccc tttgctggga ttgactctgt cagtgaggaa atcatcatga atacgctgag
      541 agatttgaaa aaagctggga agacggttct catcgttcac cacgacctca gcaagattcc
      601 ccactacttc gatcaagtct tacttgtcaa tcgagaagtg attgcctttg gtccaacaaa
      661 agaaactttt accgaaacca atctaaaaga agcttacggt aatcaactct ttttcaatgg
      721 aggtgaccta tgattgcaga atttatcgat ggattgcaaa aattccattt cctacaaaat
      781 gccttgataa cagctattgt cgtcgggatt gtagctggag ctgtgggatg tttcattatt
      841 ctacgcggga tgtcactcat gggagatgcc atttcacatg ctgtcttacc aggtgtagcc
      901 ctctccttca tcttgggcct tgacttcttt atcggagcca ttgtctttgg attgctagct
      961 gccatcatca ttacctacat caaaggaaac tcgattatca aaagcgatac cgccatcggc
     1021 attacctttt cttctttctt agccctcggt atcatcttga ttggtgtcgc taaaagttca
     1081 actgaccttt tccatatcct ttttggtaat atcctggccg tccaagatac ggatatgttt
     1141 attactatgg gtgtgggggc agccatcctc ttgttaatct ggattttctt caagcaactc
     1201 ttgataactt cctttgatga actcttggct aaagccatgg gaatgcctgt caatttctat
     1261 cactaccttc tcatggtact cctgactctc gtgtctgtga cagccatgca aagtgtcgga
     1321 actatcctga ttgtagccat gctgattacc ccagctgcaa ctgcttatct gtatgctaat
     1381 agtctgaaaa gcatgatttt cctttcctca accttcggag ctactgcttc agttttggga
     1441 ctctttattg gctatagttt taatgttgcg gcaggttcta gtatcgtgct tacagctgct
     1501 agtttctttc tcattagctt ctttatcgct cccaaacaac gatatttgaa actgaaaaat
     1561 aaacatttgt taaaataagg ggcaaagccc taataaattg gaggatctaa tgaaaaaatt
     1621 aggtacatta ctcgttctct ttctttctgc aatcattctt gtagcatgtg ctagcggaaa
     1681 aaaagataca acttctggtc aaaaactaaa agttgttgct acaaactcaa tcatcgctga
     1741 tattactaaa aatattgctg gtgacaaaat tgaccttcat agtatcgttc cgattgggca
     1801 agacccacac gaatacgaac cacttcctga agacgttaag aaaacttctg aggctgattt
     1861 gattttctat aacggtatca accttgaaac aggtggcaat gcttggttta caaaattggt
     1921 agaaaatgcc aagaaaactg aaaacaaaga ctacttcgca gtcagcgacg gcgttgatgt
     1981 tatctacctt gaaggtcaaa atgaaaaagg aaaagaagac ccacacgctt ggcttaacct
     2041 tgaaaacggt attatttttg ctaaaaatat cgccaaacaa ttgagcgcca aagaccctaa
     2101 caataaagaa ttctatgaaa aaaatctcaa agaatatact gataagttag acaaacttga
     2161 taaagaaagt aaggataaat ttaataagat ccctgctgaa aagaaactca ttgtaaccag
     2221 cgaaggagca ttcaaatact tctctaaagc ctatggtgtc ccaagtgcct acatctggga
     2281 aatcaatact gaagaagaag gaactcctga acaaatcaag accttggttg aaaaacttcg
     2341 ccaaacaaaa gttccatcac tctttgtaga atcaagtgtg gatgaccgtc caatgaaaac
     2401 tgtttctcaa gacacaaaca tcccaatcta cgcacaaatc tttactgact ctatcgcaga
     2461 acaaggtaaa gaaggcgaca gctactacag catgatgaaa tacaaccttg acaagattgc
     2521 tgaaggattg gcaaaataag cctctgaaaa acgtcattct catgtgagct ggcgtttttt
     2581 ctatgcccac atttccggtc aaatcattgg aaaattctga ctgtttcaga tacaatggaa
     2641 gaaaaaagat tggagtatcc tatggtaact tttctcggaa atcctgtgag ctttacaggt
     2701 aaacaactac aaggcggcga caaggcgctt gatttttctc ttactacaac agatctttct
     2761 aaaaaatctc tggctgattt tgatggcaag aaaaaagtcc tgagtgtcgt tccttctatc
     2821 gatacaggca tctgctcaac tcaaacacgt cgttttaatg aagaattagc tggactggac
     2881 aacacggtcg tattgactgt ttcaatggac ctaccttttg ctcaaaaacg ttggtgcggt
     2941 gctgaaggcc ttgacaatgc cattatgctt tcagactact ttgaccattc tttcgggcgc
     3001 gattatgccc tcttgatcaa cgaatggcac ctattagcac gcgcagtctt tgtcctcgat
     3061 actgacaata cgattcgcta cgttgaatac gtggataata tcaattctga gccaaacttc
     3121 gaagccgcaa ttgcagctgc taaagcccta tagaaaaaat cctctgtcac aaagagttcc
     3181 ctgctctttg aaacggagga tttttgaata ttaataaata gaagttcaat cagctaaaaa
     3241 taactacctt actctacaga tttcagggct tctaacatat caacctttct cagataataa
     3301 ttgacgaaga aaccaagcaa ggtcaaaatg atgcttactg ctgccactgg gattacatag
     3361 acttcccagc ctacctgcgg ataaaagaga atagtcgcag gcgaaatcat ttgaatcaaa
     3421 aattggtgta aatagaaacc agctaccaga ccaagtacga ttcccacaag ggacagcaca
     3481 atcgtctcac ggtaaatgta gagggtgact tcattattat gaaaaccgag aaccttgata
     3541 gtggagagtt cacggattct ctcagctacg ttgatattgg tcagattgta aaggatgaca
     3601 atagctaata gaaccgatac gatgaccaag atggtcatgg tctgattgag tgagctagcg
     3661 atagagtcga agagtcgaat ggctgaagca ttttggacaa cgctggacac cgcagattga
     3721 ttcataagca agcccgcctg actttcgata ctagttgcac tggtatccct taatgagacc
     3781 agataagtgt tggcttgggg tagctgtccg taaagttgct catagctagc ctgactcata
     3841 taaataaagt gaccaacgta gttctcagta atagcagcga cctttagttc cttaccttca
     3901 atttctaaag tctgcccaac cttgacacct gccagctggg cgagtttagc tgtaataacg
     3961 atgccatctt ttaatgtcag ctcctgctga tgatgttgaa gatggataaa gggagtcaaa
     4021 tcttccttct ctatcatcat aagagtaatg ttttgaagac cagccttgcc tttgaaatcc
     4081 ttgtctagcg ttttagaata gattttctgg taggctagta tctcctgccc tttcaacact
     4141 tctgctagct ctaccttgtc ctgattggtc gcactaggag tttcagagac aagcatctga
     4201 tactgttgga tttgttgaaa ctgtttagac ggaactcctg ctacagaaga ttggattccc
     4261 aaacctgcaa agagcagagc tacagaacct gccacaccaa agattgtcat caacattctc
     4321 tgcttataac gaaagatgtt gcgggctgtt accttatgag taaaactgag acgacgccag
     4381 ataaaaccga tacgctccaa taagatttta gctcctttga caggaggttt aggaagtaga
     4441 agctgggctg cttcggcatg aagttccctc caagccacca gatagactgg taacacactc
     4501 gccaaccaac tcaagacaag agctagtaag ctataggtcc aatagaactg aatctgggtt
     4561 tctcccacca ctatgccttt tgtaatgaca cttgaaatta cactggctag caaataatga
     4621 ccaagtatac tacctagagc cgttccgaca gtcccagcta ctagtccata aaggagaaac
     4681 ttggtgataa tatccttact acggtaaccc aaggccttaa aaatccctgc atgagttcgc
     4741 tcttcgtcta caaagcgagt catggtcgta aaggtcacca tggatgctac ggcataaagt
     4801 accacaggaa agatattgcc cactgctcga atactggatg aagcattgct atacataaga
     4861 tagccctgac cacctggcat ggtctgacga ttatagacct gataccttgg ctccgccaaa
     4921 tcgtccaaga cttgctgatg tttttctaat ttttcctttt cttgggctag attttgttca
     4981 gcttgcttta gtttgtcctc ttccttgccc aattcctgct tggcttgggt aagttgagca
     5041 ctagcctgct ctctctgaac ttgaggaaac aaggctagtt gactttcttg agcctgtata
     5101 cgagcttgag cagctgctaa acgacgcttg ccttcctgca aattagtctg agccttgtca
     5161 agggtctctt gccccttgtc tagagactct tgtccttctt ttttcaaaag ttgcagacgt
     5221 accttgccat tatctgataa agtttgttca aggtcttcct gatgttgctt ggatttttct
     5281 tcataagctg atgaaaaggc atttaaacct gctaaatctt gatatttcaa acgagctata
     5341 ttgtagactt tctgatcaaa ctgactaggt aaaatcaccc cataggctgt cagagtccca
     5401 cttccacttc ctgcgtagcc catatctcgc tgggagagga tttcagccga atccacaaaa
     5461 ccagtaatgg tataagtatg gtcttttaaa gaggaatgac cctcttcttt ttctttaaaa
     5521 ctaatctcct gtcccacgct gtattggcct tgcaaatgag tggccaaagc gatttccttg
     5581 tctgactgag gaagtcgtcc ctttcttagc tgaaaggttg aaattcgctc tggtttggag
     5641 tacagccgaa tggcatcctg cccattatcc atagtcacat ctgtcaaata gccaaactcg
     5701 acctctgcgc cctccgtctg ttttagttct tcttggtctg cttgatccaa gccatagtta
     5761 gacatgactg ccaaatccaa ggtttgagca gttgttaaat aagcattagc tgtcgcctcc
     5821 atgttgggac tggttacttt gaggcctact aaggctagag atcccaacat catcaggatc
     5881 aagatggata aaaaacgccc cttggagcct gtgaaggact gaattaagtc cttccaataa
     5941 gtttttcgct tgatcatgct agtactccaa actgtcaata tcctgaggat gctggttgag
     6001 caccacatcc ttgacactgg catcgtgcat ttgaatcacg cgatcagcaa tgggcgccaa
     6061 agctccatta tgagtcacga tgatcaccgt cgctcccttt tgacgagaca tgtcttggag
     6121 aattttcaaa acctgcttgc ccgtctgata atccaaggct ccagtcggtt catcacaaag
     6181 gagaatttta ggatttttgg ctaccgcgcg tgcaatggag actcgctgtt gctcccctcc
     6241 agaaagctgg gctggaaagt tattgagacg atgagccaga cctacatctg tcaagacctg
     6301 atcaggattc aaggcatctg tcacaatttc agaagccagt tccacatttt ccttagctgt
     6361 cagattagaa actagattat aaaactgaaa aacaaacccc acatcatttc tacggtaatt
     6421 ggtgcgctgg tgggaactat aatccgcaat attaacacca tcaatccaga tttccccttc
     6481 atcattggta tccattcccc caagaaggtt aagaactgtt gacttgcctg cacctgaagc
     6541 accaaggata ataaccagct cccccttttc aatctcaaaa ttcacatcac aattggccac
     6601 aatctccgtg tccccaacct gataacgctt gtaacagtgt ttcatctcaa tataagccat
     6661 cagacccacc ctctatcaaa caaattatac tcctcgaaaa tctctcttca aaccacgtca
     6721 gcttccatct gcaacctcaa aacactgttt tgagcaacct gcggctagct tcctagtttg
     6781 tgctctttga ttttcattga gtattacttc ctattatcat tataacgttt tttcaactag
     6841 ttgaaaactg cttatattct taaatcctta ttaaaaggca gtttcaaatt actgccttat
     6901 aacatcttct taaaaataaa attgaacaag atcaccttct gctgttgcca ccgaaataca
     6961 atctttcccc atgcatttcg cttttatttt ttcttgattc attttaatca cactcttctc
     7021 aatatctgga taagaaactc gcaaatctcc tccactcctt gataaaatgg tcaactgtaa
     7081 gagtttttta tcttcccagc tcatgctcac ttcaaaatgt ccacgtgcca ttaagcctga
     7141 aacagaacct gttgaccaag catcaggtag ggcagctaga ggtaccagat aagctgcatg
     7201 agactggagt aacatttctg ccatgccact agtagcacca aaattaccat ctatctgaaa
     7261 aggaggatgg ctacaccaaa gatttggcaa ggtggatgtc tttaactgct ctgccaataa
     7321 tttatgggct cgattgccat ctcccaaacg cgcccagaga ttgatcttat tagccttgga
     7381 ccagcctgtg ccgccatctc cacgatcatt gaggctagca cgtaccgctt caatatactc
     7441 ttgtcccttg tagctaaaga gattgccagg atagagtccc actagatggg aagcgtgccg
     7501 atgctgggcc tccactttct cattttgaaa atactgctct tcctcctcat accactccct
     7561 gattcgacca gattgagtga tttgcaaagg atttagtaaa tcagacttct ccttaacctc
     7621 agtcaacaag tcctcatcca gtcccaattc ctgagcagcc tgaataaaat catgaaataa
     7681 ctgccaaatc agagattggt cataagtatt gccaatcgaa atcggcccat gttctgggga
     7741 ataagacgga gaagacaccc aacgctgcgc ctgctgatcc ttatgtaaaa aggcattcca
     7801 aaaacgaacc gtttccctca acatgggata aattttctcc ctgagatagt cttggtccct
     7861 ataaaatgaa taggcttcat aaacggtttg catcatccac gcattggcag ctggtgacca
     7921 accccaatag taatcccaac caggtgccgt ccaaccaaag ggagtcgctt gagtatgaac
     7981 caaccaacca ttctcctcac ctttctgaga gacgattcct gcatacttta cagccgctag
     8041 acgaccatag acacgcaaat catctacata gttgatgact ggaaagaccg tctctaggag
     8101 attggtaaca taggctggcc aataattcat ctgcagattg acatttaagt gatagtccga
     8161 attccaagga ggattgtcga ccgcattcca gactccctgt aggttagctg gtagagcatc
     8221 tgggcagtct ctggacgaac taatcaataa ataccgtcca tactggaaga acagctcctc
     8281 caaagcctgc ccttcttgtg gcttataatt ttttaacaaa tcatctgtag tgaatgcgtc
     8341 aacattagct tccaaatcca attgaacacg ctggaataag gcttggtagt cctcgatatg
     8401 ccttgatttc aattgggtat agcccttttc tttagctgtg tccaccaagt ctatcacctg
     8461 ttgctctaaa tctagtttct tgcgataatt gctagcagga ttttgggcaa aatccgtctt
     8521 agcggccaag aagagattgg cataactggc tcctgatatc tgaaccctat ctgaccaaac
     8581 tctaatatct ccatccgttt cccaagctag ataactagca aaccgcagat cattatcctt
     8641 aactcttccc ttcatcaaga tatgagaatc agtaatatcc aacttacact ccttgtaatc
     8701 agatttttcc tgctcatact ttccatcaga agccaaatca caggtcaagg atagttctat
     8761 agtaaaatct agagtttccg ccccttcctt agtaaaacgc tgaaccaaga gatcatctgg
     8821 aaaactcgca aaagcttcac gttcaaatcg cgttccctta tagacataag aagtcgtcac
     8881 aagtgcctta ctaatattca gctgtctctg atagtccgtc acctgagaca aagtcgtacc
     8941 ttgctggctg aactcaatgt gaatatcccc aaaagacaga taggtcccat attgactcgt
     9001 ttttggccca attaggtgct gctcagccag ttccttagcc agattgtaat ctctcttctc
     9061 caaagcctgc cgaatctcag ctaaaaaaac atactgatcc tgaagatttc caccctgata
     9121 atctgaacta tcaggaagtg gacctccaga ccagagactt ttttcattaa attgaatccg
     9181 ttcagcccct ataaggccaa atacttttgc tcctaaagaa ccattgccta tcggtaaagc
     9241 ttcttcttcc caacccatgt aagtggttga aactggttgc ttgtaggcca gtacataatc
     9301 ttgtttttta ttccttatca tacttccata ctaacataaa aagcctagaa atcaattcta
     9361 gacttacaat tttttatttt ccaaggtagt attcagaaac gacgttcaat ttttcgtcga
     9421 attcgaatac caatggtggg aagttaggga tttccacgtc catgatctcg tcatctgaca
     9481 aacctttgat gtgttttaca agggcacgga ttgagttacc gtgagctcct acgaatacgt
     9541 ttttaccatc tttaagagct ggagcgattt tatcttccca gaatggaaga gcacgttcca
     9601 aagtcacttt caagttttca gcatctggga ttactgagtc gtcaagtgaa gcataacgac
     9661 ggtctgtgtg agctgagtgc tcatcatcac ggtccatatt tggaggcaat acatcgtatg
     9721 aacgacgcca gatgtgaact tgctcatcac caaattgttc agcagcttca gctttatttt
     9781 taccagtcaa accaccgtag tgacgttcgt tcaagcgcca tgatttttca actggaaccc
     9841 acaattggtc agaagcttca agagccaagt tagttgtttt gatagcacgt ttcaatactg
     9901 aagtgtaagc ttggtcaaat ttgataccag cttctttgat caatttacca gcgtcaatcg
     9961 cttgttgtgt acctttttca gacaaatcaa catcagccca accagtgaaa aggttagctt
    10021 tgttccattc agactcaccg tggcgagcaa aaaccaattt taccattaga tggattctcc
    10081 tttaaatttt ccgaggtttc ccctcgttta tctattctat tttacacaat ttttcacaaa
    10141 aaagctagtc aaaaccaaaa aggaaaggac tgtttgacaa tgtttggcaa tcacattgtt
    10201 tttagttgtt tctattctat cttcattatt taaccttttt ttctgcgcat cgaataattt
    10261 ttgagttgac tcttttagtt tagtaaacga gtcattattt tccatagctg tgcctttgaa
    10321 accttcctca gctttagtaa aataatcatc aaaaatattt ttataaagat ctatataatc
    10381 tgcataagtg cgtattgatt caatcacatc gtctgttaca accggtgtat cgaaagtgat
    10441 tgtttctttt gaactattgg atgttgctac tgtcttctca tcattacttg ttgaagtatc
    10501 ctttgaactt tatgttccac atgcaactag aagaaaaaga gataatagag ctactcctat
    10561 accgataaac ttttttgttc ttttcatgct aaaatacctt ttattcttct gatttgaatt
    10621 tcttcaatgt tgcaaggaat agagatcctc cgataataac aagaatcccc ccaacccatc
    10681 ctaagaatgg aatgagacta actccaccaa aaacaatcat tagtacagac ggagctgcac
    10741 ctacacgatt atctccttta tagtaaacaa tagcaatgat accaagaaca agatttgcaa
    10801 tcttcaaggc attcaagagt aaggcaacac ctgaaaaagc ccctgcagta gctcctccat
    10861 taagagttgt agcaactgtg tttaccgctg ttcccaacaa gacaaaagga ccaataagaa
    10921 gtaaaattcc tcccacaaga ccgacgatac cactaattaa agcaagtgtt tttaatttca
    10981 taataaaatc tcctttttta tttttttcaa ataaaattgt atcat
//
LOCUS       DAVLAQ010000061        10851 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000061 DAVLAQ010000000
VERSION     DAVLAQ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.061"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(255..1061)
                     /gene="yidA"
                     /locus_tag="VXB71_001716"
     CDS             complement(255..1061)
                     /gene="yidA"
                     /locus_tag="VXB71_001716"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0451796.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1074..2378)
                     /locus_tag="VXB71_001717"
     CDS             complement(1074..2378)
                     /locus_tag="VXB71_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0451797.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2450..2827
                     /locus_tag="VXB71_001718"
     CDS             2450..2827
                     /locus_tag="VXB71_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0451798.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2918..3250
                     /locus_tag="VXB71_001719"
     CDS             2918..3250
                     /locus_tag="VXB71_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0451799.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3262..4833
                     /gene="ffh"
                     /locus_tag="VXB71_001720"
     CDS             3262..4833
                     /gene="ffh"
                     /locus_tag="VXB71_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0451800.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5028..6311)
                     /locus_tag="VXB71_001721"
     CDS             complement(5028..6311)
                     /locus_tag="VXB71_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0451801.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6614..7327)
                     /gene="rsmG"
                     /locus_tag="VXB71_001722"
     CDS             complement(6614..7327)
                     /gene="rsmG"
                     /locus_tag="VXB71_001722"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0451802.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7421..7981
                     /locus_tag="VXB71_001723"
     CDS             7421..7981
                     /locus_tag="VXB71_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0451803.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7983..8882
                     /gene="htpX"
                     /locus_tag="VXB71_001724"
     CDS             7983..8882
                     /gene="htpX"
                     /locus_tag="VXB71_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0451804.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(9031..10590)
                     /locus_tag="VXB71_001725"
     CDS             complement(9031..10590)
                     /locus_tag="VXB71_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0451805.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
BASE COUNT         3167 a         2017 c         2429 g         3238 t
ORIGIN      
        1 tgtgtagatt cagggtcaat ttgaagagag tatttaaaat atcttgggaa attataattt
       61 ctccctgttt tttgagtcca atctatgagt atgagttgcc caggagtaag gccacattct
      121 aaatcgttta ggtaaaaatt gttacaatca gaatttgtgt ctctattatg attattttgt
      181 tttaaattaa atagtttgct aaaaaaattc attggatttt attgctaatc aattcttatt
      241 gaaaaatgat acttttacag tacccatgtt cggatggcgt gggcaacgcc ggattcgtca
      301 tttgttttag tgatgtattt ggcgattttt ttgatttctg gatttccatt ttccatgaca
      361 acggggtttc caacgacttc cagcatggca cggtcatttt cttcgtcacc gattgccatg
      421 gtttcatctt tggtcaatcc gagtttttca gccaagtgag taatagctga acccttgtct
      481 acattctttt taaggagttc gaggtagaaa ggagcagatt tgttgataga gtagtgctcg
      541 taaaattcgg ctggtatttt ttcaatcgca gcatcgagaa tttctggttc atcgatgaac
      601 atacacttga caatttcctt gccagccatt tcttcagggg tacggtagaa gataggcatg
      661 ctgacgaggg ttgattcgtg tacagtgtat gttccgatat tgcgatttgc agtatagata
      721 ccgtccttgg taatggcatg catgtggaca ccgagcttgc gactgaggaa ttccatatcc
      781 agataatcct cataggtcaa ggattcgctg ataatctcat ggccagtagc agtttcttgg
      841 acaagggcac cattgaaggt caccacatag tcaccttggt ctctcaactg caagtcgtcc
      901 agaagtttgg caacacctgc gatggggcgg ccagttgcaa tcacgacttt gacaccagct
      961 tctttggcat cttggatggc agaaaagact tcaggagtga tttccttttg gctgttgact
     1021 agggttccgt caatatcgac ggcgattagt ttaatactca taaatttcct cttttagttt
     1081 ttatttgggg taaaatgatc gttctcaatc aagtgtaaaa attgctgggt gatgcttgcg
     1141 aagatgctgt tttggtctaa catttctttc gggaaataaa agcgattatc tccgtggcga
     1201 cttccagcaa gggattggac gataggggac aggctagaga gttctgccag ttctccattt
     1261 ttttgtaaaa tctcaatctg tgtccttgga ttttcagatt cgggacggta aatatcataa
     1321 gggaggtcaa agttcttatg aatggcagta tagtagtcgg gatcaaagcc gatgtcctca
     1381 accaattttc tcatgctagc gagttggtct tggtcttctt gtgaaaaggt aatggattta
     1441 aagaccttgc ggttgacaaa gcgatgcgat aaatctgcaa gaatcttgtc aggactggtc
     1501 atccaaagct ggaagtaggt attcatcacg ccatcatcca gagccagata gtcagtcaag
     1561 gtcacatttt tttcgaagaa aggcaggagg tgtggagaag ttcgggcaaa gaaatccttg
     1621 tcctcaggat agagttcctt ggcgcgtttg agaagattct gtaggagaac ttccatggcg
     1681 cgtgttgcgg ggtggaaata aacctgcatg tacatctggt agcgactgag gacgtagtct
     1741 tcgatggcgt gcatgccatt gcgctgaaag gcgataccat tttcgatagg acgaatgact
     1801 cggaggattc gagtcaggtc aaattcccca taggatgctc ctgtaaaata ggagtcgcgc
     1861 aagagatagt ccatgcgatc tgcgtcaatc tgactagaaa tgagctgcac gacctgctta
     1921 ttaggatagg tatggtcaat gacactggcc accttttctg ggaaatcagg tgccacttgt
     1981 agcaggactt ggtgaatctc tgtctcagga ttttgaataa tctcctgagt aatggcttca
     2041 tggtctgtat caaagagatt ttcaaaagta tgggagtagg caccatgccc aaggtcgtgt
     2101 aggagagcag cggtcatggt caagagagac tcggcaggat tccattcctc aggatatttt
     2161 tcttcgaaaa tctctgtgat gcgtcgtgca atttcataga ctcctagaca gtgagagaag
     2221 cgactgtgtt ctccaccgtg gaaggtataa ctggaagttc ccagttgttt gatccggcgc
     2281 aaacgctgaa attcttttgt attaatcaag tcatagatga tttgattatt gacatggatg
     2341 tagttgtgaa cagggtcacg gaatactttt tcgttcatat gaccattata gcaaaatcct
     2401 gctctttttg gtaaaatagt aggacaagag acaagaaaga gggcctgatg tgaagattcg
     2461 gatgcgaaat acaattcagt ttgatgagca gttggaagtg attgaccagc tttatgatgt
     2521 ggaagtgcat gaaaaaggag attatagcta cctgcttttc tataatgagg aaaaggaaaa
     2581 agtagtgatt aaatttcatg gtcaagaact tgtgatgagt cgattttcca atcccaagac
     2641 cattatgcgc tttctaaagg atagtgatag tttagcctat attcccacac ctatgggtat
     2701 gcaggagttt attatccaaa cgaatcgtta tcaagtggat gggcaaaaga ttgaactaga
     2761 ttatcaacta caaaatcaag agggacatcc ctttgccagc tatcaattgg aaattacttg
     2821 gggctaggct tatgtctttt tcaaatttag ctatctatct tcttggatcg gcttcctagt
     2881 gtggtagatt aggctaattt ttggtataat aaaagttatg gaaatcgaaa aaaccaatcg
     2941 tatgaatgcg ctctttgaat tttatgcggc gcttttgaca gataagcaaa tgaattatat
     3001 cgagctctac tacgctgatg attacagcct tgctgaaatt gccgaggagt tcggtgtcag
     3061 tcgtcaggct gtctatgaca atatcaagcg aacagaaaag attctggaag attatgagat
     3121 gaaattgcac atgtactcgg actatattgt ccgcagtcag atttttgatc agattttgga
     3181 gcgctatccc aaggataact ttctgcagga gcagatagaa attttaacaa gcattgataa
     3241 tagagaataa gaggaagaaa aatggcattt gaaagtttaa cagaacgttt gcagaacgtc
     3301 tttaaaagtc tacgtaaaaa aggaaaaatc tctgaatctg atgtccaaga ggcaaccaaa
     3361 gaaattcgct tggccttgct tgaggccgac gttgctttgc ctgttgtaaa ggactttatc
     3421 aagaaagttc gtgagcgtgc agtcgggcat gaggtcattg atacacttaa tcctgcgcaa
     3481 cagattatta aaatcgttga tgaggaactg acagccgttt taggttctga tacggcagaa
     3541 attatcaagt cacctaagat tccaaccatc atcatgatgg ttggtttaca aggggctggt
     3601 aaaacaacct ttgctggtaa attggccaac aaactcaaga aagaagaaaa tgctcgtcct
     3661 ttgatgattg cggcggatat ttatcgtcca gctgccattg accagcttaa gactttggga
     3721 caacagattg atgtgcctgt ctttgcactt ggaacagaag taccagctgt tgagattgta
     3781 cgtcaaggtt tggagcaagc ccaaactaat cataacgact atgtcttgat tgatactgcg
     3841 ggtcgtttgc aaattgatga gctcctcatg aatgagcttc gtgatgtgaa agcattggct
     3901 caaccaaatg aaattctcct cgtcgttgat gccatgattg gtcaggaagc agccaatgtt
     3961 gcgcgtgagt ttaatgctca gttggaagtg actggggtca tccttaccaa gattgatggc
     4021 gatactcgtg gtggtgcggc tctatcggtt cgtcacatca ctggaaaacc aatcaagttc
     4081 actggtacag gtgaaaaaat tacagatatc gaaaccttcc acccagaccg tatgtctagc
     4141 cgtatccttg gcatggggga tatgctcact ttgattgaga aagcttctca ggaatacgat
     4201 gaacaaaaag cccttgaaat ggctgagaag atgcgcgaaa acacctttga ttttaatgat
     4261 ttcatcgatc aattagatca ggtgcaaaat atggggccga tggaagactt gctcaagatg
     4321 attccaggta tggccaacaa tccagcactt caaaacatga aggtggatga acgccagatt
     4381 gctcgtaaac gtgccattgt gtcttcgatg acacctgaag aacgtgaaaa cccagatttg
     4441 ttaaatccaa gccgtcgccg tcgtattgct gctggttctg gaaatacatt cgtcgaagtc
     4501 aataaattta tcaaggactt taaccaggct aaacagctca tgcagggtgt tatgtctggg
     4561 gatatgaata aaatgatgaa gcaaatgggg attaatccaa ataaccttcc taaaaatatg
     4621 ccaaatatgg gaggaatgga tatgtctgcc cttgaaggaa tgatgggaca aggcggtatg
     4681 cctgacttat cagctctcgg aggagcagga atgccagata tgagccagat gtttggtggc
     4741 ggtttgaaag gtaaaattgg tgaatttgcc atgaaacagt ccatgaaacg tatggctaac
     4801 aaaatgaaga aagcgaagaa gaaacgcaag taagacaaga gattgatgca aatctcattt
     4861 gatgagaaaa taaagtaaaa atttctatga taaaacgtac agtatcaagg ttttagaata
     4921 tctgatatta tacgtttttt gattttaata attttgttaa gacactttta ttatgatata
     4981 cgaaaaatcc actcagctgt ctgagtggat taggtgtatt tagactctta gtctttattt
     5041 tcgtatggca agatcaagtt caagatgatt cctgtcatgg ctgaaagggc agtacctgaa
     5101 agtgtaactg gaccaagttt aaggatagct cctccaagtc caagaaccaa catagcactt
     5161 gcgatgatga ggtttcgcat ttgagcgaaa tcaacacgtt ctttaatcaa gactttcaaa
     5221 ccattgctgg cgataacccc atagagaagg attgacatac caccaagtac agcgtttgga
     5281 atagttgaaa tcaaggcagt gaatttacca aggaagctga gggcaatcgc gatgaaggca
     5341 gcgttacgga taactgagac agaagcgata cgagtcatac cgataacccc tgtattttct
     5401 ccgtaagttg tattggctgg tccaccaagg aaggcagaaa cagaagttgc gataccgtca
     5461 ccaataagag tacggtgaag acctggttct tttaagaatt gacggccaca gatttgaccc
     5521 aaaacagtat ggtctccgat atgttcagaa attgttacga tagcgattgg caagatagcg
     5581 atggcttctg gaccaaagta aagattgtac tctttaaagg caccacctgt gctaaatggc
     5641 aagtagaaac caggaatttc gaaccagttg gctttaagaa ctggtgtaaa gtcaaccaag
     5701 ccaagagtta gtgcgaaaag gtaaccaccg ataatggcaa agaggaatgg aatgattcgt
     5761 aggaagcctt ttccttttgt attgataaag gcagcaatta ggaaagtaac aacggctacc
     5821 agagcatttt tccaatttcc gtctgctaca agacctgcat tggtaacagc tgaacctgca
     5881 agtccaagac cgataacgat gatcatagga ccgataatga ttggtggcaa gagtttatca
     5941 atccattttg ttcctacaaa tcggatgctg gtagcaacaa ggacatagac caaaccagtc
     6001 aagataaccc ctgtttgggc agcagataca tcccccccca tttctttcat agccagtgac
     6061 atagctgtga taaaggcaaa tgaagaacct agataaactg gaactttaaa accagtagca
     6121 atcatgtaga tgagtgttcc aacacctgaa gcaaaaaggg caacagatac aggcattccc
     6181 aaaatcaatg gtaccaagat ggtcgcacca aacatggcga aaacgtgttg gaagctaagg
     6241 agaattcctt ttccatccga aggacgttgg tcaacgtcta gtaacaaatc aacagttgat
     6301 tcttgtttca tataaacctc acttttgggc atcagaaaag agcccattat tttacagcaa
     6361 taggccctca gagtaagact tctctaaaat ctagacttta aagagtttca aatatttctg
     6421 cgtcttcgtc acctcacggg atgacattaa aaacctttgc ttaggatagt atagcagaaa
     6481 aaaatgattt tgtaaatcat tttttcccga gcctagaaat aaaagagcga ggctgatttt
     6541 gtaaatcatt ttttcccgag cctagaaata aaagagcgag gctgattttg taaacatttg
     6601 tttactaaaa aatttaaagt gggcgtttat ttggcatacc agccttacgt ggatatttat
     6661 ttggtgtttc ttttttcttt tctaccactg tgatatagcg cggatctcta ttcggtaggg
     6721 cgtagctgag attgtcttcg accttactaa aaaggagatt gagggcattc ttagcttcta
     6781 acaactcctc aggcgcattg ctagccttga gtgctaatag tttgccacca accttaaggt
     6841 agggaatagt caattcagat aggacctgca tacgggcaac cgcacgagct gttacaaaat
     6901 catattgagc acggaagttc ttgtcttggg caaaatcttc ggcacgtccg tggtagaaat
     6961 gaactccgtt caaatccagt tcttgagcca agagttgtag gaagttgatg cgcttattga
     7021 gtgaatcaat aatggtcaca tctaactccg gatagagaat tttcattggt agactaggaa
     7081 atcctgcccc agccccgata tcaagaagtt tgatagtttc attgggaatc aaaccttgaa
     7141 gaatgggtgc aatcgaatcg taaaaatgtt tgagataaac ttcttccttg tccgtaatcg
     7201 ccgtcaaatt aatcttctca ttccactcga ccaagagctc aaaataacgt tcaaattgtt
     7261 ctttttgctg gtccgaaagt ggaagattct gctcggcaag caagttgtaa aatgtttctg
     7321 gtttcatagt tatttccttc tttagtatca tcttatttta ccacaatcat taaaaatttg
     7381 atatactggt actaatctaa aagtagaaag gacttatatc atgacttgga ttattcttgg
     7441 agttatcgct cttattgtta tttttgtgat tgttagctat aacggtttgg ttaaaaatcg
     7501 tatgcaaacc aaggaggctt ggagtcagat tgatgttcag ttgaaacgtc gaaatgacct
     7561 cttgccaaac ttgattgaga ctgtaaaagg ttatgccaaa tatgaaggtt ctacccttga
     7621 aaaggtggca gaactacgta accaagtggc ggcagcgact tcaccagcag aagctatgaa
     7681 agccagtgat gccctcactc gtcaagtttc aggtattttt gcagttgcag aaagctatcc
     7741 agatttgaaa gctagtgcta actttgttaa attgcaagag gagttgacaa acacagaaaa
     7801 taaaatttct tactctcgtc aactctataa cagtgttgtc agcaactaca atgtaaaatt
     7861 agaaactttc ccgagcaata ttatcgctgg aatgtttgga tttaaagcgg cagatttcct
     7921 tcaaacacct gaagaggaaa agtcggttcc taaagttgat tttagcggtt taggtgacta
     7981 agatgttgtt tgatcaaatt gcaagcaata aacgaaaaac ctggattttg ttgctggtat
     8041 ttttcctact cttagctctt gttggttatg cggttggtta tctctttata agatctggac
     8101 ttggtggttt ggttatcgca ctgattatcg gctttatcta cgctttgtct atgatttttc
     8161 aatcgacaga gattgtcatg tccatgaatg gagcgcgtga ggtggatgag caaacggcac
     8221 cagacctcta ccatgtagtg gaagatatgg ctctggtcgc tcagattcct atgccccgtg
     8281 ttttcatcat tgatgatcca gccttaaatg cctttgcgac aggttctaat cctcaaaatg
     8341 cggctgttgc tgcgacttca ggtctactag ctatcatgaa tcgtgaagaa ctagaagctg
     8401 ttatgggaca tgaagtcagt catattcgta attatgatat ccgtatttcg actattgcag
     8461 ttgcccttgc tagtgctatc accatgcttt ctagtatggc aggtcgtatg atgtggtggg
     8521 gtggagcagg tcgcagacga agtgatgatg accgagatgg aaatggtctt gaaatcatta
     8581 tgctagtggt ttccctacta gctattgtac tggcacctct cgctgcaacc ttggttcagc
     8641 tcgctatttc tcgtcagagg gaatttctgg cagatgcatc tagtgtcgag ctgactcgca
     8701 atccccaggg aatgattaat gccctagata agttggacaa tagcaaacct atgagtcgcc
     8761 acgtcgatga tgctagcagt gccctttata tcaatgatcc caagaaaggt ggggggttcc
     8821 aaaaactctt ttatacccac ccacctatct cagaacggat tgaacgttta aaacatatgt
     8881 aaaatgaagg ctggaaaaaa gtctttaaaa tctgaaaaac gcataatatc aggtgtgaaa
     8941 acttgatatt atgcgtttta ctatgggaag atttacttct ttttctccta aaattgtgtt
     9001 tttgccccac ctatctgcta tgttgcaaat ttataaatct tctaaattaa ctagcttcaa
     9061 accgtgttct gtcatgcgat agatgatcga gcagacttct tttaagaaac gacggtcatg
     9121 cgaaacagtg atgagaccgc caggataagt ggcaaagagt tttctgattt ggggttgaga
     9181 agtgggagaa aagtttcgtg tgggttcatc cagcaggaga aagtttggtt tgcgcaggac
     9241 taaatccaaa agcaggagtt ttccctgttg tccgccagat aaggagcgaa tttgatgctg
     9301 catttctgga taactgaaat tgagactagc taggtgagat tggattttct gtagttcctc
     9361 tttttcccca gttttactga gataggctat tggggataaa tccaattgca gttttttgtg
     9421 gtaatcttgt ggcataaaac caagtgaaat ctctctttta tcattcagaa gtctctgtaa
     9481 cttggctaac agagttgatt tcccaacacc atttggcccg ataataccga ttttttcttg
     9541 gccacggaca gttagttgta gtttttgaac caaaactcgg tcgtcaatgg acaaattttc
     9601 tttttccagt tggactaaga ctttagaagc tggtaatggt tggatgtctg aaaagaaaag
     9661 ttggatttgt tcctcttcaa gtggtttttg agtcatggac tgagctgcct tttcgtagcg
     9721 tttttcttgt gagaggacag ttttcatctt tttagccaat aggcgaccgg cagtactatc
     9781 tttggtagct cgaagcgcag tttctacatt ttgcttaact ctccgatgtt tttccatggt
     9841 tttatcgtag gctctttggt tgttagcagc ttgctgactt tgtttggcaa aattagcctt
     9901 tctctgctca ctatagctat catagtctaa atgctctact agcgtttccg cttctttacg
     9961 gtgtttgacc agtcgcaagt gaacaatagt gtctgccgtt tcagaaagaa agtcttcatc
    10021 atgggaaatg aaaataacgg tttgcctggt cttttgaatc tggcctttta gccaatcaac
    10081 tgtctcaagg tctaggtcat ttgaaggttc atctaaaaat agaatctcaa agggtttggc
    10141 taactcatgg ataagctgaa ttttcaaagc ttctccccct gatagattgc caatctcttg
    10201 gtcacttgcg aaacgattgc tatcaaaatg caattcctcc gccaaacgat agaggatact
    10261 gtagtctaaa tcaatagaat ctaaaaagaa gtagtcgtgt aaagttttct ttttcagctc
    10321 ctcgggaagt ttttgaggaa tgtaggccag tgactgatag tcagattgga tgtctccctt
    10381 gatagtgaaa tcagacaaat cttcccccat taaagtttta agtaaggttg atttaccatt
    10441 tccttcttcg ccaataatag ctaccttttc cccgtcttgt atggtcatgc ttaggtcaga
    10501 gacaaggtct cgtaaatctt tgttttgtgt gatggtcagg tgattgattt ttatcatact
    10561 attgcccttt ctagaatgtc gatagtgcat aacaaaaagc tctactttac ctagtagagc
    10621 ccaaagtcta tgtcaaaaaa actctattaa catgccagaa aaagagcata aaagagcaca
    10681 caaaaagaga caaaaacaag atctactaaa taaaggttct ttatttgata gacttagttg
    10741 ttcatgtctc ccttacctcc gagtattagt atctttatat tataccttta aggaaatttt
    10801 gtcaacagaa aactggaaat tctatgctct aaaatccaaa aacaggtcca t
//
LOCUS       DAVLAQ010000062        10667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000062 DAVLAQ010000000
VERSION     DAVLAQ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.062"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..1745
                     /locus_tag="VXB71_001726"
     CDS             <1..1745
                     /locus_tag="VXB71_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0451806.1"
                     /translation="YKTNNLFDALEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKE
                     VSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDR
                     YRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRF
                     GTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKD
                     GAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYD
                     QSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLR
                     KIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRN
                     GYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKA
                     QGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDP
                     NGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLD
                     QTGDFRSSIFENKK"
     gene            1789..7002
                     /locus_tag="VXB71_001727"
     CDS             1789..7002
                     /locus_tag="VXB71_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0451807.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            7256..8107
                     /gene="ylqF"
                     /locus_tag="VXB71_001728"
     CDS             7256..8107
                     /gene="ylqF"
                     /locus_tag="VXB71_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0451808.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8094..8873
                     /locus_tag="VXB71_001729"
     CDS             8094..8873
                     /locus_tag="VXB71_001729"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0451809.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            8889..10439
                     /locus_tag="VXB71_001730"
     CDS             8889..10439
                     /locus_tag="VXB71_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0451810.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3667 a         1741 c         2170 g         3089 t
ORIGIN      
        1 attataagac taataattta tttgatgcat tagagaaata tagaaaagca tttgtaccag
       61 ataaaacaaa taatgagtgg tttaaagaac aaactaaagc atatattgta gaagaaaaat
      121 ctactattaa agaggtaagt gataagcaat caatagctgg tagtccatat tcaattggag
      181 tatatgatag attaactagc ccatcttgga aatatccaag tatggtgttg ccgctattaa
      241 cattacctga aaaatcggtg tttattatag ccaacatttc gactataggt ttcggtgctt
      301 atgatagata tagaagtaaa gaacatccag caggaactga tttaaatgac tatgttgaga
      361 aaaaagctaa agaagcggct gttagattta gagatcacta tgattattgg tatagaatac
      421 tagatgataa aaataaagaa aaattatata gaagtgttct agtctatgat gcatttagat
      481 ttggtacaga tgaaaaagaa gataaagata catatcaagc aacttttgaa actaatcatc
      541 cagctataaa acatttcttc ggtccagcgg gaaataatgt tgttcataat tctaatggag
      601 catatgctac aggggatgca ttctattata tggcatatcg catgcttgat aaagatggtg
      661 cggtaactta tacacacgaa atgacacata actcagatag agaaatttat cttggaggct
      721 atggaagacg aaatggactt ggaccagagt tttatgctaa aggactgcta caagctcctg
      781 atcatcctaa tgatccaaca gtcactatta attccatatt aaaatatgat caatcagaag
      841 aatcaacaag gcttcaagta gcagatccaa ctcaacgatt tggaagtgtt gatgatctaa
      901 ataagtatat gcataatatg tttgatgtaa tatacatgct tgaaatacta gaaggtaaag
      961 ctgtagctaa attagataca aatcaaaaat atgatttatt aagaaaaata gaaaatgaat
     1021 ataaacctga tcctgatgga aattctgttt atgcaacgaa tgttgtacgt agattaaaac
     1081 cagaagaact tactaaatta actacattta acagtttgat agaacatgat attataacaa
     1141 gaagaggtta tgtagatgaa gcaacttata agcggaatgg ctactataca attaatctat
     1201 tctcaccaat ttattcagca ttgagcagta aaataggaac accaggagat ttaatgggac
     1261 gacgtattgc atttgagtta ttggcagcca aggggtacaa agacggtatg gttccatata
     1321 tttctaatca gtatgaaaaa gaagcgaaag ctcaaggaaa agttattaca tcatatggta
     1381 aacaaatagg tttagttact gatgaaattg ttctttcaaa agtatttaat aaccagtata
     1441 attcttggat agatttcaag aaagatatgt ataaagaaag agaagataaa tttggaaagt
     1501 taaataaagt tagttttatc gatccaaacg gttcttgggc tcgacaacag aaagtgacta
     1561 ttgataatat taatagactt gaaaaaatga ttgaagatgc agtaaaattt gatgctgagg
     1621 atgaagttgc caaattatat cctgagacaa atagtagagt tcttaaactg aaaaaagcaa
     1681 tctttaaagc ttatcttgac caaaccggtg attttagaag ttcaattttt gagaataaaa
     1741 aatagtgttt actattagga aataaaaagt gaaggtggag gattagaatt gtcattatta
     1801 aaaaaagata aattttccat tcggaaaata aagggtattg ttggttcggt attcttgggg
     1861 agtcttttat ttgcaccgtc agttgttggt gcatcgactt atcattactt agattatagt
     1921 agtttgacac aaactgaacg tgatcaactc aaacaaggta gacctgatga atccaaagag
     1981 tcatatgctt tggattatga aaaagacgca ctaccaaaca caggaagttc tcaatctatt
     2041 atgactgcat tgggtttgtt agctatcggg agtcttattg tgattatcac aaaagataat
     2101 agaaataaaa aaatagctac atttttgatt gtaggggcga caggtttagt tacactatca
     2161 actgcttcag cacttaattt gaatgctaac atccatgagt ctggacgtga tggtgtgttg
     2221 caaatttctg gttacagata tgttggttac ttggagcttg atgataaaac tgtttcgtcg
     2281 gtttctccag catcaactgt ttcgccagtt gagcaaccca aagttgtaac agagaaaggc
     2341 gaaccggaag ttcatgagaa gcctgactat acgcaaccaa taggtgcaaa ccttgttgag
     2401 cctgaagttc atgagaaact agcatacact gaaccagtag ggacaacagg agtagatgaa
     2461 aatggaaact tgattgaacc acctgttaac gacatcccag aatatactga gccagtaggt
     2521 acaacaggag tggatgaaaa tggaaacttg attgagccac ctgttagcga cattccagag
     2581 tatactgaac caatatctac agtttcagaa gttgcatcag aaagagaaga gttgccttct
     2641 ttacataccg atattcggac agagactatt cctaaaacca ctatagaaga atctgatcct
     2701 agcaaattta taggcgatga ttctgttaga caagttggtg aggatggcga acgtcaaatt
     2761 gttactagct atgaagagtt acatggcaaa aaaatcagtg acccagttga aacagtaact
     2821 attttgaaag aaatgaagcc taaaattctt gtaaaaggta ccaaagaaaa acctaaagaa
     2881 aaaacggctc ctgttttgac cttagataga acaaatacaa atgtattaaa ccgatccgca
     2941 actctttctt atcatttagt taatacagat ggagtcacaa tcaataaaat tactgcgaca
     3001 attaaagatg gaaatgaaat tgtcaaaaca gtagatttga cttcagagca attagataag
     3061 caggtagaag atttaaaatt ctacaaggac tataagatag agaccactat gacctatgac
     3121 cgtggcaagg gagaagaaac tgcaacatta gaagagaaac cacttcgctt ggatttgaaa
     3181 aaagttgaaa ttaaaaatat cgcatctact aatttagtga aggtaaatga cgatggtact
     3241 gaaacaccta gtgattttat gactgaaaaa ccttcagatg aagatgtgaa gaaaatgtac
     3301 ttaaaaatta ctagtcgtga taataaagta acacgtttag cagttgataa aattgaagaa
     3361 gtgactgaag aaggtaagaa actttataaa atcactgccg aagctcaaga tttgattcaa
     3421 catacagacc caacgaaggt tcgtaacaag tatgttcatt atattgaaaa accagttcca
     3481 aaagttgatg acgtttatta taactttaaa gagttagtag atgccatgaa tgctgataaa
     3541 aatggtacat ttaaaatcgg agcagatttg aatgcaacga atgtaccaac acctaacaaa
     3601 caatatgttc caggtacgtt taagggacat ctatcaagtg ttgatggtaa acaatataca
     3661 attcataaca ttgcccgtcc cttatttgac cgtgttgaaa atggttctgt gaaaaatatt
     3721 aatttaggta atgtggatat caatatgcct tgggctgacg gaatagcacc tgttgccaat
     3781 atggtgaaaa atgcaactgt tgaagatgtt aaggtaactg gtaatgtagt tgctaataac
     3841 aatattgcgg gtatcgtcaa taaaatcgat agtggtggtc agttgacaaa tgtagccttc
     3901 atcggtaatc ttacaggtgt tggtgataaa ggtcaatata tggctggcat tgccggtgag
     3961 atttggagag gtaatcttgc aaaagcatat gtcgaggctg atattgttgc taacagagcc
     4021 cgtataggtg gtttagttgc taaaacagat aatggtaacg actctatggg aattggtaaa
     4081 tacggttcaa ttcgtaaatc agtcaccaaa ggaaccatta agactaaagt tttgtttgaa
     4141 acaggtggat ttatcaatag caatcttcct tttggtaaac ttgaagataa tatttcaatg
     4201 atgagagttg aaaatggtga agagttcttt ggttcttccg atttggacta cgatggtggt
     4261 tatttcacaa atggctggtt agagcgtaac tttgttgtca aaggtgtcag ttcaggtaag
     4321 cattcataca aacgttctcg tgacaaaatt aaagaaatta gtcaagatga agctaataag
     4381 agaattgcaa attttggact tactgctgat aaatacgaaa tcaacgaacc tgtggtcaat
     4441 cgcttaaatc gtttaaccag aagagaagat gaatataagt caactcaaga ctacaaatcc
     4501 gaacgtgatt tagcttatcg taatattgag aaacttcaac cattttataa taaagaatgg
     4561 attgtcaacc aaggtaacaa acttgcagaa gattcaaact tagctaagaa agaagtcctt
     4621 tctgttacgg ggatgaagga tggtcaattc gtgaccgatt tatcagatat tgataagatt
     4681 atggttcact atgctgatgg tactaaggaa gaaatggatg ttactaagaa tactgattct
     4741 aaagtccaac aagtgcgtga atatagtgta tctggtcttg gtgatgttgt ttatacaccg
     4801 aatatggttg ttaaaaatcg tgataaattg attgctgatg ttaaatctca attatcaagt
     4861 gtggaattga tttcacaaga agtaagagat ttaatgagta gacgtgataa acctgcagag
     4921 aatacggatg aacgtaagaa tggttatatt aaagatctat acttagaaga aagctttgcc
     4981 gaagtgaagc aaaatctaga taagttagtc aaatccttgg tcgaaaatga agaccatcaa
     5041 ttgaatggtg atgaagctgc gataaaatca cttctcaaga aagtggaaac caataaagct
     5101 aaaatcatga tggctctgac ttatctcaat cgttactatg atatcaaata cggtgacata
     5161 agtataaaaa acatcatgat gttcaaacct gatttttatg gtaaaacacc aagtgttatt
     5221 gacagactca tcaacatcgg ttcaagtgaa aagaacttga aaggggatcg gactcaggat
     5281 gcttaccgtg aaatcatcgc aggtaatact ggtaaaagta atttgcgtaa cttcttagaa
     5341 tacaacatgc gtctgtttac agaggataaa gacatcaatg attggtttat ccactcagct
     5401 aagaatgttt atgtttcaga acctaagaca acaaatacag agttgaaaga taaacgtcat
     5461 cgtgtgttcg atggtttaga taacggtgtt catggtcgta tgattttacc acttctaacg
     5521 cttaaagatg cccatatgtt cttaatttca acatataaca cgatggcgta cagttcattt
     5581 gagaaatatg gaaaacatac agaagaagct cgtaatgagt tcaaaactaa gattgatgaa
     5641 gttgcacatg ctcaacaaac ttatttagat ttctggtcca gattagctct gcctaatgtt
     5701 cgtgatagac ttcttaagag tcaaaatatg gtaccgacac cagtttggga taaccagacc
     5761 tacaatggtt ctcctgtagg tcgtcgagga tttgacagta aaggtaaccc tatagctcca
     5821 attcgtgaat tatatggtcc aacatggcga caccatgata gagactggcg tatgggcgct
     5881 atggcatcaa tattccctaa tccaaataat gatgacaagg tcttgtttat ggtgacggat
     5941 atgattagcc catttggtat ttcagccttt actcacgaaa caacacacgt aaacgataga
     6001 atgctttact tcggtggtca taagcatcgt caaggtacag acgttgaagc ctatgctcaa
     6061 ggtatgttgc aaacacctga cagctcaacg actaatggtg aatacggcgc acttggaatt
     6121 aacatggctt accatcgtcc aaatgatggt aaccaatggt acaacccaga tcctgacaaa
     6181 ttaaagacac gtgatgacat tgaccgctac atgagaaact acaatgaagc tatgatgttg
     6241 cttgatcatg tagaagctga tgctgtactt cctaaaatta aaggagacaa tagtaagtgg
     6301 ttcaagaaga ttgacaaaga aatgcgctct aagattcagt ataatgatct tttaggtcca
     6361 aaccaatggg atagtatccg tgatttgaaa gatgaagaaa aggtaatgac tttatctagc
     6421 gtcaatgatt tagtggataa taacttcatg acaaaacatg gaaatccagg taatggacgt
     6481 tatagaccag aagattttac accaaactca gcttacgtaa atgtcaatat gatggcagga
     6541 atttacggtg ggaatacgag tcaaggtgct cctggttcat tatcatttaa gcacaatgct
     6601 ttccgtatgt ggggctatta tggttatgaa aatggcttta ttagttatgt atcaaataaa
     6661 tacaaagcag aagcagataa aaacaaccac ggtttactaa gcgataagct aataattaat
     6721 aaagtatcga aaggaaactt taatactctt gaagagtgga agagacattg gtacggggaa
     6781 gttcttgcta aagctaagaa aggttttgag gctatcgata ttgatggcgt ccatatcagt
     6841 aactatgatg agttaaggcc tttatttgat aaagcagttg aagaagattt gaagaaacca
     6901 gatgacttct ctcacactgt tgctcttaaa tctaaggtct tcaaagccct tcttaaaaac
     6961 acagacggtt tctttaataa actgtttaaa gaagacattt aaatgtttag aatatagaag
     7021 gaacagtttt ttgctccctc tgaaaagtca tcatttgatg gcttttttct atatagggta
     7081 cttgaaaggc tatcatcgga caaaataaag aaggcatgat ataatataag gtagatttct
     7141 atgccataaa acaaaaaact gtttgaacat cattcatttg agaacccttt atgttcaaac
     7201 gatagtaaaa taaaatagga tctctaaacc cttgctacga aaggaaaaaa actcaatggc
     7261 tactattcaa tggtttcctg gtcacatgtc taaagcgcgt cgacaggtgc aggaaaattt
     7321 aaaatttgtt gattttgtaa cgattttggt ggatgcacgc ttacctctat ctagtcaaaa
     7381 tcctatgttg accaagattg ttggtgataa accaaaactc ttgattttaa ataaggcgga
     7441 tttggctgat ccagcaatga ccaaggaatg gcgtcagtat tttgaatcac aaggaatcca
     7501 aactctggct atcaactcca aggagcaagt gactgtaaaa gttgtaacag atgcggccaa
     7561 gaagctcatg gctgataaga ttgctcgcca gaaagaacgt gggattcaga ttgaaacctt
     7621 gcgtactatg attatcggga ttccaaacgc tggtaaatca actctgatga accgtttggc
     7681 tggtaaaaag attgctgttg ttggaaacaa gccaggggtc acaaaaggtc aacaatggct
     7741 taaaaccaat aaagacctgg aaatcttgga tacaccgggg attctctggc ctaagtttga
     7801 ggatgaaact gttgcactta agttggcatt gactggagct atcaaggatc agttgcttcc
     7861 tatggatgag gttaccattt ttggtatcaa ttatttcaaa gaacattatc cagaaaagct
     7921 ggctgaacgc ttcaaacaaa tgaaaattga agaagaagcg cctgtgatta ttatggatat
     7981 gacccgcgcc ctcggtttcc gtgatgacta tgaccgtttt tacagtctct tcgtgaagga
     8041 agtccgtgat ggcaaactcg gtaactatac cttagataca ttggaagacc tcgatggcaa
     8101 cgattaaaga aatcaaagaa ttccttgtga cagtcaagga gttagaaagc cctatttttt
     8161 tagagcttga aaaggataat cgctcaggag ttcaaaagga aatcagcaag cgtaaaagag
     8221 ccattcaagc tgaattagat gaaaatttgc gcttggaatc catgctttct tatgaaaaag
     8281 aactttataa gcaaggattg accttaattg taggtattga tgaggttggt cgtggtcctc
     8341 ttgctggtcc tgtagtcgct gcggccgtca ttttacctaa aaattgtaag attaaaggtc
     8401 tcaacgacag caagaaaatt cctaaaaaga aacatctgga gattttccaa gccgttcaag
     8461 accaagcctt gtcgattgga attggtatca tagataatca ggtcatcgac caagtcaaca
     8521 tctatgaagc aaccaaacta gccatgcaag aagcaatctc ccagctcagc cctcaaccag
     8581 agcacctttt gattgatgcc atgaaactgg acttgcccat ttcacaaacc tccattatca
     8641 aaggagatgc caactccctc tctatcgcag cagcatctat agtagccaag gtaacacgtg
     8701 atgaattgat gaaggaatac gatcagcagt tccctggcta tgatttcgct actaatgcag
     8761 gatatggcac agctaaacat ctggaaggcc tcacaaaact aggagttacc ccaattcacc
     8821 gaaccagctt tgaacccgtt aaatcactgg ttttaggtaa aaaagaaagt taattgaaag
     8881 gaaataccat ggaggaacag tcggaaatag tccgttctaa gaaagaattc gcctttgcat
     8941 ccagcactat actatcccaa gttggtcgag gaatcattgt cggcctcatc gttggaatta
     9001 tcgtcggatc ctttcgtttc ttaattgaaa agggcttcca cctgatacaa ggagtttatc
     9061 aagatcaagg gtacttagtg cgcaatcttt ttgtactggt tttgttttat atactcatct
     9121 gttggctcag tgccaaacta acacggtcag aaaaagatat taaaggctca ggaattcctc
     9181 aagtcgaagc cgaactgaaa ggcctcatgt ccctcaactg gtggggcatt ctttggaaaa
     9241 aatatgtgct aggtattctt gctattgcca gtggactcat gctgggtcga gagggaccca
     9301 gtattcaact tggagcagtt ggtggtaaag gaattgccaa gtggctcaaa tccagtccag
     9361 tagaggaacg ttccttgatt gccagtggag ctgcagcagg tttagccgca gcctttaatg
     9421 ctcctattgc agcacttctc tttgttgtag aagaagtcta tcaccatttt tcgcgctttt
     9481 tctgggtctc aactctagca gccagcatcg tagcaaactt tgtgtctcta ctcatgttcg
     9541 gtttgacacc agtattggat atgccagata acattcctcc catgacccta gatcagtatt
     9601 ggatatatct cgtcatggga attttccttg gattttcagg ttttctctat gagaaagctg
     9661 tattaaacgt tggaagagtt tatgacttga ttggtcaaaa aatccatttg gatagggctt
     9721 attatcccat cttggctttt atccttatca taccagtcgg aatcttctta cctcaaatca
     9781 ttggtggcgg aaatcagctt gtcctttctt taactgaaca aaattttagt ttccaagttt
     9841 tattagctta ctttttaatc cgctttattt ggagtatgat tagctatgga agtggactgc
     9901 caggaggaat tttcctcccc attttagctc ttggttcttt gcttggtgcc ttagttggtg
     9961 ttatctgtgt caatcttgga cttgtcagtc aagagcaatt ccctatattt gtcattctag
    10021 gaatgagtgg ctattttgga gccatatcaa aagctccctt aaccgctatg atcctcgtaa
    10081 ctgagatggt aggagatatt cgcaacctta tgccacttgg tcttgtcact cttgtttctt
    10141 atattatcat ggatttgctc aaaggtacgc cagtctatga agccatgctg gaaaaaatgc
    10201 ttccagaaga agtatctagc gaaggagaag ttacacttat cgaaatacca gtttctgata
    10261 aaattgctgg gaaacaagtt catgaactca acttaccaca caacgtcctc atcacaactc
    10321 aagtccataa tggcaagagc caaacagtta acggctcaac cagaatgtat ctgggtgata
    10381 tgattcacct ggttattcca aaaagtgaaa ttggaaaagt caaagatttg ttgttgtagt
    10441 atgatcattt acataattta tgttatgtaa atgatcagtt tgatttattt agaaaaccga
    10501 ttctcagaaa tgagatcggt tattttttac tgatgaggaa ttttacatat aaataattga
    10561 actttattaa aaataagact ataattaagt tagaaatgat aaagtataaa gctagaaagg
    10621 agtttactgt atcaaatctg tacagtaaga ttaaaatcat gaaaaag
//
LOCUS       DAVLAQ010000063        10666 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000063 DAVLAQ010000000
VERSION     DAVLAQ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10666
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.063"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(377..1570)
                     /locus_tag="VXB71_001731"
     CDS             complement(377..1570)
                     /locus_tag="VXB71_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0451811.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(1708..3150)
                     /gene="gtfA"
                     /locus_tag="VXB71_001732"
     CDS             complement(1708..3150)
                     /gene="gtfA"
                     /locus_tag="VXB71_001732"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0451812.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            complement(3427..3507)
                     /locus_tag="VXB71_001733"
                     /pseudo
     CDS             complement(3427..3507)
                     /locus_tag="VXB71_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3508..4341)
                     /locus_tag="VXB71_001734"
     CDS             complement(3508..4341)
                     /locus_tag="VXB71_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0451813.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(4355..5221)
                     /locus_tag="VXB71_001735"
     CDS             complement(4355..5221)
                     /locus_tag="VXB71_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0451814.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(5235..6494)
                     /locus_tag="VXB71_001736"
     CDS             complement(5235..6494)
                     /locus_tag="VXB71_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0451815.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(6586..8748)
                     /locus_tag="VXB71_001737"
     CDS             complement(6586..8748)
                     /locus_tag="VXB71_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0451816.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            8856..9716
                     /locus_tag="VXB71_001738"
     CDS             8856..9716
                     /locus_tag="VXB71_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0451817.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRAGQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            9713..10648
                     /locus_tag="VXB71_001739"
     CDS             9713..10648
                     /locus_tag="VXB71_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0451818.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
BASE COUNT         3425 a         2277 c         1851 g         3113 t
ORIGIN      
        1 tttactatgt cttttcacac caaccttatt ccgaattcaa ttacttttgt gatttacata
       61 tatagattaa gactatcttt tatactttaa aatttctcgc taccttatcc actatatgct
      121 cctcgctatc acgtttctat tcatagccta cgatttcact attgctttct ctgacaattc
      181 ttatttcctg cgtcagactt aaaacgatct atccccagac cattttaatc cgctacctca
      241 cgatagtcag gcttggggag cgctattgta ttcaccggta gtggatccct acagaggact
      301 tacacctcag atgcacgaca tgcccatcgt ataaaaaatc tcctacccaa ggtagaagat
      361 ttcaaactta taaaacttaa tccgtcatgt ccgataccaa cattcgatgc tccaatggaa
      421 tactgcacat aactagcaag aaaataaagc ctgactgaat ccagaagaga gccaagtcaa
      481 aaattccgtg cacagcaacc actgtaagga aagatagata aaggccgata atcggacgtt
      541 tccccgactc ctgactcata tccatcatca agcgaacagg agcaacagaa gacagaacta
      601 ataaaatggt acccacaatt ccgtaactca gaatcgtatc aatataaaga ctgtgggcat
      661 gttcatgata aggagcatgt atccgaggat aagagtgcat ataggtcaat ggcccttcac
      721 cccaaaaagg attttgctta aacaaggcca tcccagcatc ccagatagaa atgcgttctt
      781 ccatagaaga gtctaaagta cccattcgaa ctcccaaatc actagaaaag aggaaactca
      841 aaccaatcgc gaagacccca atactaagcc aaaaggcctt ccagttttta atagtcgtaa
      901 agagatagat aattgctcca gcgataatag caggaaaggc agttcgattt tgagtaaagt
      961 tcaaaccaaa gagattaaca aagcctgcaa tcacacagaa tactttcaac caattcaact
     1021 tggtcgttgt aaacagatag aaagcaatca taatacagaa acaacaaata attccataat
     1081 aattaggatt aaagaaggtc acttctgccc ggttctgatg ccacacctgc atattggggg
     1141 aaagaaaagc atagttaaat ttcttcacaa tttggaaatg ttctaaactg gcaaaagcag
     1201 ctgacaagac actaccaaac aagacgaact gcaaaatcaa tcgaaagaat ttatgggata
     1261 aaatcgactg atagtgcaaa aagaaaatag taaatagaaa cattcctact gaagccacaa
     1321 gacccatcca attttgtgca agaatggata taacagtact atagccaaga aaaagaagca
     1381 gcatcgaatg ctcccccatt ttctgaagaa tacttttcat gtctcctgta aaaatcagac
     1441 tgataatata taaacagaat acaactacaa aaagataaaa gggtaaaaag atactcagga
     1501 taattcccaa taaaatcagc tctttactag acaacccctt cagcttttca ataaagccta
     1561 ttgatttcaa aatgaatcct ttctctccaa atcagctgat tcagataata gtaagctatc
     1621 ctatattgta ccactttttt agcaatttga aaacaaagga aacgttttcc aaaataaaaa
     1681 ccctatttta tccaccatat caaggcttca aaatgttact tcaactccat tctcaattac
     1741 ccgataagtc tgattttgca agtcaatttc tgctactgct gttacggact tatctttatt
     1801 ttgacgtttg attacaatgc tgtgagctgt tggtgtctct atctcagtag tcccttctag
     1861 atcaaaggct tctgaacggt tacggaaaga aaatagattg agaagggcct tcacaacagg
     1921 tcgttgcact tcttttgcta tttcctcgtt gctatagtaa tgacgattaa tatttcgacc
     1981 ttctttagtt tcttctaata atttcaagtc attcttgcct gctaatagac ccacatagta
     2041 aacctgagga atacctgggg caaaagcttg aattagacga gcgagaaaat acttgacatc
     2101 atcatctcca agcgctgaat agtaggttga attgatttgg tagatatcta agttgttata
     2161 ctcggcacta gagtacttac gtttgacatt ggctccaacc ttatagagtt catttgaagc
     2221 atagtcaatc tcctcatcgg tcaggatatc cttgacatct actactccaa tcccatcatg
     2281 ggtatctagc gtcgtaaatt gcttcatcgg gctcatcttt aaccacttag ccaaacgctc
     2341 tgttctggaa ctgtaaagag tataaagtgt caccattgga agagcaaaat cataaacata
     2401 gtaatcatgg tctgctattt taaactgaat cgaatagtgt tcatgaatct caggtaaaag
     2461 ctctgtccca tactcagcag cgatatctcg aactttgtcc aataaatccc aaatatctgg
     2521 ttccacaaag aaatcattag tatccaattt cttcactgca taagcaaagg catctagacg
     2581 aatcaaatca cacccattac ttgccaagtg ctgaatggtc ttacggataa attccatagt
     2641 tacttctttg gtcacatcaa gatcaatctg ctcctcacca aaggtattcc acaaatgttc
     2701 cactgaacca tcttcaaaca caatctcttg ctttggtgca cgatccttac gcttgtaaat
     2761 taaatctaca tcagactgtg tcggacggtt ttctggccaa aacttatccc agtttaaaaa
     2821 gagatcttta aattcactgg cttcatgttt ttcttgatag tccttataat acttggattg
     2881 acgagaaata tgattaatca taaaatcaaa cataagataa tatttctcac ctaaacgctt
     2941 aacatcctcc caatcaccaa aagctgagtc cacttcgtcg tagtcaactg gcgcaaatcc
     3001 acgatcacct gttgatggga aaaatggtaa aaggtgaact cctccaatag catctccaaa
     3061 atgctcttcc aaattatcat ataagtcttt aagattattt ccaaggctat cagaataggt
     3121 aatcaacatg gttttatttt gaattggcat cattactctc ctttttctaa ttgaagccaa
     3181 gtctcatatg atctggcttc gtaaatcaaa ttcattttaa atctctattt atcatcaaac
     3241 tcgtactaat atagactgtg ataaacaaag tactactttc ttgttttcta catagaatta
     3301 tcaacaagct gaactcttcc tctgtgtcaa agactataga ttccatgagc tcttcttata
     3361 ctcttcgaaa atctcttcaa accacgtcag cttcacctta ccgtaggtat ggttactgac
     3421 ttcgtcagtt tcatccacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct
     3481 agtttgctct ttgattttca ttgagtatta cttcactgcc ccgttgctca ttcctgaaat
     3541 gatatggcgt tggaagaaga gatagacaat ggtgatactg ataatgccga ccacgtaaga
     3601 ggcaaagctt ggtccgtagt cgttgaaata ttggcctgcg tagttgtatt ggaacaaagg
     3661 cagagtccac attttggaat cccggttcaa gacaaggagt ggcaacatga agtcattcca
     3721 gaaccaaagg gcattgatga tcatggttgt cgcatgcatc ggtttcatca ttgggaagat
     3781 gatgcggaaa taggttgtaa attgattagc cccatcgatc tctgctgctt catccagact
     3841 ttctggaatc gagattttga tatagccaac atagagaaag agggtctgtg gaatcgcata
     3901 ggtcaagtag agcaagatca aaccaaaggt attagccaaa ccgagtttac tcatcataac
     3961 cgtaatcgga atcatgatga cttggaaagg tacgaagatt ccgaggatta agagggtata
     4021 catgatggta aagacttttc ttttactcat attgcgagcg atggagtagg ctgccatagg
     4081 gataaagatc attactgcaa gtaaagacaa gacagtgatg acgacagagt tccaataata
     4141 gcctccaatc ccatcagcta agagacggct aaagttgtcc catgtgaagt tggttggaaa
     4201 gccaaagaaa ttatctacaa tatccttagt gggtttgaag gaactaaaga gggtagcaag
     4261 gagcggcact aaaatcagaa ccgatcctag aatcaataga atgtatttgc caatcagggc
     4321 ttttctttca tcttgtttca tcatgcttct cctcttaaat ttcaaatttc ttagatactc
     4381 tcaattggat gatcgaaatc actacaatta agaggaacaa gattacggca atggcattgg
     4441 cataaccgaa ttggttgttt ttaaaggcat agttataaac caagagccca agtgaggttg
     4501 tggcattgtt tggaccacca ccggtcatgg caaagacttg gtcaaaggca gtcagcccac
     4561 cttttagggc taggataaag accatagaga cacttggtag caagtaaggc aattcaatgt
     4621 tccagaaaac ttgcttgcta gtcgcaccat caatccttgc tgcctctgta atctcagttg
     4681 gaatagattg caaaccagct aggaagatga tgatgggcat agccacccct tgccaaagaa
     4741 ggacaaagac agccgcaaag attgctcccc acttagtccc taaaagactg gtttggagaa
     4801 attcaatatg aagggcattc ccaatcgctg gaagaccgta gttgaagact tgcttgaaga
     4861 tcaaagccac tgtcaaacca gataaaacag ctgggaagaa gaaccaagca cggaagaagg
     4921 tttggccttt gattttagag ttcaagacac gcgcaatgaa gatcccgagt gcaatctcac
     4981 caaccaccat ggcaatcgta atgattgcgg taaagccaat cgcattcatg aattttggat
     5041 ccatgaagag gagcttaaag ttgtttaagc cgacaaattt gtagttgtaa gtcaatcctg
     5101 tccagttggt aaaactgtaa aaggctcctt gaaacatcgg cacatagaag aaaattgctt
     5161 gtaacaagag ggggatgacc acaaaagccc atgcccaata tttttgtaat acttttttca
     5221 tagtctctct actcctaatc cacatccgct ttcatcgggt taaagaaggc attcaaatca
     5281 ttgaccatgc cttgtttatc accggtcaag acatagttca tggtcaaggt atggaagtct
     5341 gcttcactgg tccagtattg ttgcaaccag accaagtgac gatccgtaaa ggcatattcg
     5401 gtcataccag caagcggtga atcttctcct gcttgtttga ccccttcgat cgctgttgga
     5461 gatccgtcca catcgtagta tttttgcatg acttctggac gggtcatata ttccacaaag
     5521 gcattggctt cttttggatg tttggtggtg gctgagatag accatgccaa gtctcccgca
     5581 ccaacggtta agctttgtcc tttttctttt cctggaatca tgaaggtccc aatcttaaag
     5641 ttcggttttt gttcattaat cgctgtgatc gcccaagacc catttggtgt catgaggaca
     5701 tccccacgtg cgaaggctcc gataacatcg gtatagccag caccttccca gttcttttgc
     5761 ttagagccat tgatgcgaag gatgtccatg accttgatgt catctttcat aatcggatcc
     5821 gacaatttaa tggcatttgg ttgagaataa cgaaggtatt gatttgcttc ttttcctcca
     5881 cctgttgctg tcgcaaaggc taattgattg taaccattga gtgtccaggc atctgcacct
     5941 gcaattccaa atggtgtttg tcctttagca acgatatctt tgactaactg ttcaaattca
     6001 tcccaggttt caggaacctt caagcccagt tcttcgaatt tatctttgtt gtagtaaatt
     6061 ccataagcat tagctgtaaa aggaacgtta taaacttttt cgtttacagc atatttttca
     6121 gcgtaggcat ttttcacgcg tttcaggtag tctttgttgc tcaaatcttc aaaaacacct
     6181 gcttttgccc attcttgcag ttcgatggac tgtgggtaaa tattgaccac atcaggcaca
     6241 tctcctgcga gaacgcgtgt cttcaatact tcaccagcat ttggtacatt gacgactttg
     6301 accttgatct tagggttttc cttctcaaaa tcacgagtga tttcttccaa ggttttggtc
     6361 atttcttttt tctggttgaa atactcgatg gtcactgtgc catccgcaga tttaccatag
     6421 ttggagcaag cgccgagccc aaacaaagct aaacctgtag ttgcaagaag tccgattttt
     6481 ttataccatt ccattagaaa gcctccttta taaatttata cacccttatt gaactgcacc
     6541 ccaaaagtta gacagaataa atctaacttt tggggtcagt acatatcata gttttctaaa
     6601 aatatactgt ctactcaaaa aatctccttg ggataagata acagttaagc ccgcatacat
     6661 tagttctgca cctgagtaaa cttcgccatt ttcctgtaat ttatatagtc cctcttcatc
     6721 caaatctttt aattttaaag ttgtttccat ggtctctaca acagataaaa cgcgaacgta
     6781 ggttacaatc gtttgatttc cgtaattaaa ttgtacagct gcttcattgg atgcagtatc
     6841 aggattaatt agtctatact gctgtcctaa ctgaactact ggtcgtaatt ctttatacaa
     6901 gttcacctga ttagcaatcg tagctttctc ttcatctgat aaatttgtca aatcaagctc
     6961 atagcccaaa tttcccatca ttgctacatg gccacgtgtt tctaatggtg tcattcgtcc
     7021 catctgatga ttcggtactg ctgacacatg agcccccata gaaatggttg gatagagata
     7081 ggatgaaccg tattgaattg gtaaacgtgc aatggcatca gtattatcac tagcccagac
     7141 ttgtgggaaa tagcgtatca taccaagatc atttcgtcca ccaccaccag agcaggactc
     7201 aaagagaata tggctgtgct tctctgtcag ataagaaacg agttcgtaaa gccccagcat
     7261 gtactgatga gattgcatct gtgtctctag ataagttaat ccattcccta gcttagtgat
     7321 attgcggttc atatcccatt taatgtaatc aatctcatga taagatagga gttgatctaa
     7381 gacacttttc aagtattcta ctacctgagg attggcaaga ttaagtacta attgattccg
     7441 agaataagta tgctcataat caggaacctg aatagcccag tcaggatgtt gacgatacaa
     7501 atcactatct acagaaatca tttcgggttc taaccaaagt ccaaactgca aacctctttc
     7561 atggatagct gaaatcagac tttctagact tccacccagt ttttcctcat taacaaccca
     7621 atcacctaaa gcacgattat catcaaaacg attgccaaac caaccatcat ctaatacaaa
     7681 aagttcaatg ccaactttct tagcttcatc tgctaactct aacagttttt ctctctgaaa
     7741 gtcaaagtaa gtagcttccc agttattgat tagaattgga cgttcttttt tagaaaattc
     7801 acttagcata atgtgcttca gtacaaaatt ctgactttca tgactaatac cagttaatcc
     7861 ctgatctgaa tgagtcacta aagctaccgg tgtttcaaag tattcctcag gggctaactt
     7921 ccaagaaaag ttttctggat taatgccaat agccacccga acttcattca attgattttt
     7981 ttgaacaaaa gcttcaaagt tgccactata cattagttga atagcaaaca cattcccagc
     8041 atcctctgtg actccttgtt cgcatagtag aagagctggt gtttgagcat gaccagaagc
     8101 acctcggttt gaactaatcg aaaagattcc ttgttctacc tgttgacgtc taacagtctt
     8161 ttcacgagca taagcaccct gcagagttgc tatttcataa tctgcagctg gaaaatcagc
     8221 cataaaagaa aaatctttat ggatgacaac ttcctgatta ctattattat ctaatttact
     8281 gtagctagca atagtcgcat cattattaaa agtagtataa tacaaagtca gactaagttg
     8341 agccttagaa tcttctaaca ttaagacaag agtctctgta tcgtccatgc tatgtggaga
     8401 aggtaagccc tgtggaccat tctgaccttt taaaatcttt gcttctacaa atcgaaagtc
     8461 tgttacttca gttacattat gctgaacctg tatggttggt ttcctaaaat ctcctaagcc
     8521 atgttgtcca aaaatttgac gttgagtatc taaactaaag gttcgattag tagccgttgg
     8581 atttcctgaa aaggcatggt ctcgttcata aacactattg gaacctttat agttcttaat
     8641 agtctttcct aaatgtttca aaagtaagta gccatttcga ttttcaataa tcaaacttag
     8701 atttttactc tcaacataaa atagattatt ctctatccta actcccattt acttcacctc
     8761 atcactttat tgattatatt ttatcacctg aaatcgcttt ccaaaataga aaaatgtctc
     8821 aagaatatgg taaaatgtta ggtaggaggt agcacatgtt agttttttca gaataccaga
     8881 ctggaacaat cgaccttgcc ctaagctttt atggatatga ggaatgcaca cctaattact
     8941 cttttggtcc agccattcgt gatacatacg ttctacatta cattactaaa ggacaaggaa
     9001 aatttcatta caagggtaaa attgttgatt taaaagaagg agatttcttt ctattaaaac
     9061 cagaggaact aaccttttat caagcagata gtaaagaacc ttgggcctac tactggttag
     9121 gaatcactgg agggaaagcc cctgattatt ttgctctttc ccaaatttct gatcaatcct
     9181 atctcatcca atctgaaact tgtcataccc agactactgc aaaactcatc tcagacattg
     9241 tccgcttcgc tcagattaca aaatcaagtg aattagctca actccatatc atgggacaac
     9301 ttcatgaact gatgtttcat ctgggaacta ttgctcccaa tcagaaaaaa aagaatattt
     9361 catcaaccca ccaactctat cttgaatgca aacgattaat tgatagccac tatcctcaat
     9421 cacttacaat tcaagattta gcaaaagaac tatccgttca cagaagctac ttatcaagcg
     9481 tattcaaaga atttaatacc ttatcaccca aagaatacct actctacgtt cgaatgcacc
     9541 gagctggaca acttctcgaa aatacccaag agtccatcaa ggtaattgca tactcggtag
     9601 gtttttcaga tccactccat ttttcgaaag cttataaaca atactttaat cagactccaa
     9661 gtcatacaag aaaagaatac tctcaatacc aactagtgag aaaggcaaca ttatgaaatc
     9721 ctaccaagct gtctaccaaa tcctatctaa agaaaccgac tatatcagcg gagaaaaaat
     9781 cgcagaaaaa ctatccctaa gccgaacatc aatttggaaa gctatcaagc gactagaaca
     9841 agaaggcatt gaaattgata gtatcaaaaa tagaggatat aaactaatga atggtgacct
     9901 tattcttcca gagattctag aagaaaatct tccaattaaa gtcagcttta aacccgaaac
     9961 aaaatcaaca caactagatg caaaagaagc aattgattta ggccatgaag caaataccct
    10021 ctatctagct tcctatcaaa cagcaggccg aggacgtttt caacgttcct tctactcacc
    10081 acaaggtggt atttatatga cactccatct taaaccaaat ctcccctatg acaaattacc
    10141 atcctacaca ctacttgtag ctggagctgt ctacaaagct attaagaacc taactttaat
    10201 agatgtcgac ataaaatggg tcaatgatat ctatctaaac aatcataaaa ttggaggaat
    10261 ccttactgaa gcaatgacct ctgtagaaac tggcttagtc acagatatca ttattggagt
    10321 aggtatcaat ttcactatta aagacttccc tcaggaatta aaagaaaaag ctgccagctt
    10381 atttaaagct acagctccta taacaaggaa tgaattgatc atagaaatct ggcgtgcttt
    10441 cttcgaaaca ccagcagaag agctattata cctatacaaa aaacagtcat tcattctagg
    10501 aaaagaagtc actttcacac tacagcaaaa agactacaag ggacttgcta aagacatctc
    10561 agaaaatgga aaacttttag ttcaatgtga taacggaaaa gaaatctggc taaatagtgg
    10621 cgaaatttct ctcaatagtt ggaagtaaaa taacacaatt ataata
//
LOCUS       DAVLAQ010000064        10653 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000064 DAVLAQ010000000
VERSION     DAVLAQ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.064"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(12..1436)
                     /locus_tag="VXB71_001740"
     CDS             complement(12..1436)
                     /locus_tag="VXB71_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0451819.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(1981..4260)
                     /gene="pulA"
                     /locus_tag="VXB71_001741"
     CDS             complement(1981..4260)
                     /gene="pulA"
                     /locus_tag="VXB71_001741"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0451820.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4372..6330)
                     /gene="ligA"
                     /locus_tag="VXB71_001742"
     CDS             complement(4372..6330)
                     /gene="ligA"
                     /locus_tag="VXB71_001742"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0451821.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDIASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6423..7601)
                     /locus_tag="VXB71_001743"
     CDS             complement(6423..7601)
                     /locus_tag="VXB71_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0451822.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7681..8544)
                     /locus_tag="VXB71_001744"
     CDS             complement(7681..8544)
                     /locus_tag="VXB71_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0451823.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8547..10448)
                     /locus_tag="VXB71_001745"
     CDS             complement(8547..10448)
                     /locus_tag="VXB71_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0451824.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3194 a         2354 c         1901 g         3204 t
ORIGIN      
        1 ggttttacac gttatttcac atcaaaaaca atggatttga catttgtcat cgcttcaatg
       61 ctatatttaa ttccttgcac tccagctcca gaacctttga caccaaggaa tgggaaatta
      121 tctggaccac gctgggtttt attattaatg tggactgtac ctacttcaag tttttcagca
      181 atttcaaagg cttttttgaa atcatttgta aagactgatg attgaaggcc gaattcagat
      241 tcgttggcaa aggcaatagc ttcctctaca ctagccacac gaatgattgg taaaacagga
      301 ccaaatggct cttcccatgc cactttcata tcttttgtaa cttggtcaaa aagcactggc
      361 cagagaagat tgccctcacg tttgattggt gtaagagcct gagcttcttt ttcttgtgca
      421 tcctcaatca agccccaaat gaagtcggct gaagcattgt caataacagg tgtaatatca
      481 gcattgtcaa atggatcacc aactgttaat ttagaaactt cttcctgaag caaagtagct
      541 aatttatctg ctacactttc gagaacaatg acacgtttaa tggccgtgca acgttgtcct
      601 gagtagctaa aggctcccgc aacaatttgc ttggcagcat gttccaaatc tgcatcttct
      661 agtacaagag ctgcatcttt cccaccaagt tccaacatga taggacgcat accagctaaa
      721 cgaccaatac gttctccaat aggagttgaa cctgtaaagt tgatgaagtt gacttctttg
      781 tgctcaatga tataatcccc aatttctgaa ccacgacctg taatggtgtt gaaaacacct
      841 gccggaatcc ctgcttcttc aaatgcttta gccaacaaga gtccagaaat ggaaccttgt
      901 gttggtggct taaacatgac cacattccct gcaatcaagg caggtgcaat tttagaagca
      961 gataaattaa ctggataatt aaagggagca atcgctagca cgataccaac tggttcacga
     1021 cggacaacag ccagtttgtt tttacttgct gcctcaaaac caccaccttc cattgcttgt
     1081 ccagtgatac ggagaccttc ctcagcagca taacgaatca agtctgctgt acgcactact
     1141 tctccaattg ctgctttaat cccttttgct acttctttgg caaggatagt accaatttct
     1201 tccttatcgc gttctaaaat agctgctgtt ttatgtaaat aagccgcacg ttcaactgct
     1261 gataaagctc gccatgctgg cagggctgca cgcgcagctt gcatagcctc atcagcttca
     1321 gtctgagtca tggctggaac tgtacccaat tcttcttgat tgattggtga ataaatcgta
     1381 atttcttgtt cagatgattt ccattttcca tttactaaat tctgatatct tgtcaaattc
     1441 ttgtcctcct gaaaatgatt aagatatatt ttaccaaatt ttcagaaaat cacaaccctt
     1501 tttgcaaaat ttttgagatt attttcacaa acttgatttt tcaaagtata ctcaataaaa
     1561 ataaaaaaaa tccactacgt caaggcgagg ctaatgtggt ttgaagaaat tttcgaagag
     1621 cgtgaatgag tatcatctat agtaaaataa aaaaactgaa caatttggtt ggggacagcc
     1681 aaaccaattt ctcacaatgt ttcagaaaca agggtgtgct actccaattt cagcctacta
     1741 taactgtcat agattgctga aacaaagtct aggtaaaagt cttcataata aaaagacctc
     1801 ctatcaagtg ttcaaaaact ttgataggag gtcttgtttt gtgaaaatat ttatcaaatt
     1861 ttctatacaa gtgagctgtt agccaggttc tttctattct ttcaatttca atgaatggat
     1921 tttttactaa tactcataac tgggaatttg tctgtgtaaa aatagcgaga tagatggtat
     1981 ttataaaaca ctcaagacag ctagactaat atcatttaaa acattatctt cttttgagcg
     2041 actgttggtt accaacatag ctaaatttcc tgcattttca aattgatagg gttctgattt
     2101 agcattcaca accaccaaga ggtgttcttt gccgtgaact tcatagataa ggtagccgct
     2161 atgttcaatc gcagaatgca caaagacatg atggtaaatt tcatcatagc tagagtaaga
     2221 aaaggcacca gtttttgtct tcaatcggat gacttgacgg ataaactcaa tactgtcttg
     2281 acgctcatta atcaagttcc agttcacttg gttcacactg tcaggagcat tatagctatt
     2341 catcgcacgc tctctatcat catgggtcaa ctcaccattt tcaccagtcg caaccagttt
     2401 ggtacgacca aattcttgac cgatttccat aaaggccatc ccctgcatga gcagattcat
     2461 ggctgtggca gtttcgacct tgcgcatgat ttgctctgaa ctttggtctg gatgaagggt
     2521 tgccaataaa tcgtgaagat tgtaattgtc atgggcttct acatagttaa gcacctgatt
     2581 tggatgtgta tagcttccta attcacgact tcctaggatt gctttagcta gaattggctc
     2641 tgtcgcagca ccactgacaa aacctgactt gatagcacca taaacttctc cccctttgac
     2701 agcatcgcgc tgattgtcat taaagaaacc aatatttggc atctggtagg cattgtcctt
     2761 cttggcctta tcataagggg caagacctgt tcccatatcc catccttctc catagaggat
     2821 aatgttggag tcgatttcat ccaagctttg acgaatcatc tgcatggtct tgacatcatg
     2881 aatccccatc aagtcaaaac ggaagccgtc aatattatat tcctgcaccc agtatagaag
     2941 agaatcaatc atatacttgc gaaacatttc gtgttcactg gctgtttcat ttccaacacc
     3001 cgttccattc tggaaggtac catctggatt catacgataa tagtaatcag ggactgttgt
     3061 ttggaatggt gcatcaacaa ctgagaaggt atggttatag actacatcca taatgactcc
     3121 aatacccgca tcgtgataag cttgaaccat caccttcaaa tcacgaatga cctgagctgg
     3181 atcatctgga ttagttgaaa aactagtttc tggcgcgtta tagttttgtg gatcataacc
     3241 ccagttgtag gttacatttc catcctcatc gtattcttta tgacggtctg caattggttg
     3301 caattgaaca taattgtagc ccagcttctt gatgtaatca aaagcagttg actggccgta
     3361 ttggttaact gttccagcct gagcagcacc caagaaagtt cctcgaagat gttcatctac
     3421 acccgatgta ggtgatttag tcaaatcacg aatatgcatt tcacagataa ctgccttaca
     3481 tggattttcc aagcgccaag tagcctccga accgtgctta acctcgaagt tttcaacttg
     3541 cttttctaca tggctcagaa tagctgaacg tttgccatca gggctggtcg cgattgtata
     3601 aggatcacgt gtcagtgttt ggtgatgagg gaattggact tgatactgat aagccttacc
     3661 taccaaatct tcctcaacat ccaaactcca gacaccgatt gtattgtcct tatgattata
     3721 agagtagcta ttgcctcttt tcatctcaaa agtcttccaa acgggtgcat cattagcagc
     3781 tgattcataa acgacaactt gcacttctgt cgctgtaggt gaccagaggg aaaaatgagc
     3841 ctgattgtcc tctacacggc aacccaattc tccttggtaa ccccaatgat ggtcaaaact
     3901 agcactgtta atggccttat caaaggcaaa aggattttga tttttataga aaggactggc
     3961 aatagcagga ttttcagagt aataaatcct atcatcgcct tccaaaatcc agacctctgt
     4021 taatagggga tagtgattaa aacggataga atattcttta ctagtttgac ctgtatgaac
     4081 cacaaaattc aagctttcta taacatgtga acttgggtgt tcaaagctaa ataaagctcc
     4141 aaaataatct tctttgtagg ttagcaaatc aattcgttga tcctgacttt ttacaaagga
     4201 gcaagtgtca tattctccat tcttacgatg gtaatgaatg cgcatagggt agttatacat
     4261 tttttatttt tcctttttac tttgtttcta tttcactaat aaatttttgt caatctcgtc
     4321 tcaattaaca gacatagtca tattctctaa actctgtttt taaacgatcc attacaaact
     4381 ttctagccat gcctcatctc tgacctggat accaagttct tgtgcttttt gcagtttact
     4441 tccagcgtct gcacctacca cgacgaggtc ggtcttttta gaaatactac ctgtcacttt
     4501 ggcacccaga ctttcgagtt tacttttagc ttctgagcgc ttgagtcgtt ccaattttcc
     4561 tgtcaatacc acggtcaaac ctgacaaggc cgcatccgct actaccgtct gtcctttata
     4621 gtccagattg accccagttt ctttcaattc tctgagcaga atttcagagc cttctgtcgc
     4681 aaaataagtc tgaagacttt tggcaatcac gccacctaga ctttcaatac tagccacttc
     4741 ctctgaatct gcctgagaca gattttcaat tgaatggaaa tattgaagta aaagctgact
     4801 aaccttgctt ccgacatgac gaattcccaa accaaataag agcttctcgg cagaattttc
     4861 ctttgatgct tggatagcct gatacagttt agcagcggac ttttccttaa ccccctctaa
     4921 aaggaggaaa tcctcttctt gcaaacgata aatatccgcc acatccttga ctaaattagc
     4981 agcaaaaagc ttctcaacaa tagatggacc aaggcctgta atattcatag catcacgaga
     5041 agcaaagtga atcaagcctt ccatgatttg agcagggcaa cgcggattga tacaacgtag
     5101 ggccacttca tcttcaaagt gcaacaagtc agagttacaa cttggacagt ttgtagggat
     5161 atctagtttt tcttcagaaa cccgtttgga ctctaccaca cgtaaaacgg cagggatgat
     5221 gtcaccagcc ttatatacaa tgaccgtatc gtcttttcgg atatcttttt cagcaatata
     5281 atctacattg tgcagggtcg cacggctaac agtcgtaccg gcaagttgta ctggtgttag
     5341 attagcagtt ggagttacaa caccggtacg gccaactgtc cagtcaactg ataagagttg
     5401 agcttctttt tcttcggcag ggaacttgta ggctactgcc cactttggag ccttaactgt
     5461 aaaaccaagt tcttcttgac ttgctatgtc gttgaccttg attaccactc catcaatatc
     5521 gtaaggcaga ttttcccgtt cctgtcctac ttcttggata aaattccaga tttcatctat
     5581 gttttcagcc aagattcgct taggattgac cacaaaacct agttgttcta ggtacttcaa
     5641 acccttttct tggctatcac gagttgaagg gctggcttct tgatagagaa acgttgcaag
     5701 attacgcttg gcaactactg ctgtatccaa ctgacgcaga gttcctgctg ccgcattacg
     5761 aggattagca aattcaggct ctccattttc ttggcgcact tggttaactt ggtcaaagga
     5821 agcgcgtggc atgtaacatt ccccacgaac tgtgatatct agttcttctg gcaaagtcaa
     5881 agggatgtcc ttaacacgct tgaggttttc tgtgatattt tcaccaattg aaccatctcc
     5941 acgtgttacc ccagcaacca aaatcccctt ttcataagtc agcgagatag ataagccatc
     6001 gattttcagc tcacaaatat aggtcggatg agccacttcc ttacgaacac gcgcatcaaa
     6061 agcatctagc tcctcacgtg aaaaagcatc ctgcaaacta taaagaggat actgatgact
     6121 gtatttttca aaaccatcta aaaccttgcc accaacacga tgagtcggac tgtctgctag
     6181 cacttgctct ggataagcag tttctaactc gaccaactca cggtaaaggc ggtcatactc
     6241 actgtctgca accgagggat tatcgctggt atagtactca gtcgcatagc gattgagcaa
     6301 agcgactaac tcattcattc ttttattcat aagaccattt taccataaaa caagccctcc
     6361 tcacaaacga gaagggcgga aaaaacactt agtttgaaat tatttttgaa actcaagcaa
     6421 ccttatatca atttttcaaa atgagttcga acataaataa acgatataca agacaagatg
     6481 ataacaccac ttccaattat caggaaagaa gagagatgta cacttggcaa gactgtcata
     6541 aatccttttg caataggcat aaatagaata gctaaggtaa aaattgtact cagtactctt
     6601 ccaagaaatt cgctctcaac cttggtttgt acttgagtaa aaaagtgaat attaaaaatc
     6661 gtcataaaca attcacaaac taaatttcca gaaaaggaaa gaaaagttgg aagtggtaat
     6721 cccatcataa aaactccgac acctgtcaaa gccagtaaaa tcaaaagatt ataaatatta
     6781 gctttaattt tactagctag aagagcccca atgatggaac caatagcccc catagttaaa
     6841 atacttgcat aggctccttc tgacccgtaa agctgattcg aaaagggaag tagaaattca
     6901 aaagctgcaa aaaagaaatt aacgctggaa gctaccagca aaaggaagaa aatttcttgc
     6961 tgatgccaga tatagtgtaa cccatccttg atatctacaa aaatatctct cccagtaaaa
     7021 gcctttttct cttgaacttt tgcttcctct tttggaagga aagccactag aacaaaagca
     7081 atgaaaaaag tcagcgagtc tagcagtagc gtcatattga gacttgcaaa ctgtaaaaca
     7141 aggaaggaaa gaacaggaga gctaacacct acaacctgca aaaccagctc taagcgagaa
     7201 ttatagatca caatctcatc tttctccacc acttcagtta tgatagcttt attggctgtg
     7261 cgagaaaagg caaaagcaat agcctgcaca atgttagcaa caatcaaagc gccaatcatc
     7321 cagctatcat tccttatgaa agaaatagcc agacaaagaa tcccacaaac aagatctgcc
     7381 gtcattaaaa tcttacgacg agaaaaacgg tctgaaataa ctccgccaaa gggattgacg
     7441 agaatagatg tgacgagctc agaaatctga tacattccta aaactgtctg tcctatagtc
     7501 cccatagaag ccaaccagac actatttcca taatcataga gcatatttcc cattttattg
     7561 atagccccac ggctaatcaa ctgcactgca tagcgattca tattaaagct cctctcaaat
     7621 tttgaaacta ttgtatcaaa accgaaagga gctttttatt ttttccctta tttgggaaaa
     7681 ttaacttttg acaaattttt cgtagtgttc ctgataatag gctacttgct ctggaagacc
     7741 taacacatca aaaatatgca tggccttttg catctgctta cagccttctt tacactgtcc
     7801 tttttgatat aaggcaaaac cttttaaata atggaaaaca ttacgctcat aaagcttaat
     7861 acctttgtca ataatcttct ctgtataagc ctcaaaatag ttggcattat aaaaagaaga
     7921 atgctctaaa caatgctggt aacaattgag ggccaaaatc aaaactaatc tcttatggcg
     7981 actaatctct tggtaaaatt cctccctctc cataacttct ctaccaatcc gagtgacata
     8041 gtctacatcg tagaaactat agaggttacc gaaaagaatc aactcataca tggtccattc
     8101 ttctgttttg aagagataat ctgctacctt atccaaatca tcctgcttca tatcataagt
     8161 cgcatctctt tgacaaatca gaccttgtag caaaatccag ttcagctcaa aataaaggga
     8221 agtcgtcgaa ctcttagact tttcaagttg ttctctttga agcttttgaa aacctgcaat
     8281 atcgtttgaa tagtaaagtg ggataatctg tgccatcata gacacatgtt catgattatg
     8341 aaaattcctt gccttatcca tgaaattttc gattgttaca tgaatgttat ccaaaatctc
     8401 aaagaaacgg gagactgcca ggtcagactc cccaagctca aagcgagata actgagaggt
     8461 agagcaggat tcgcctgctg cttcctttaa agaataattt ccacttgttc gaaattcacg
     8521 aaatactttt ccaagatgtt ccatctttac acctgatctg ataattcttc ccactcaagc
     8581 atagcttctt cctgacgatg gctgattttg tccagctcag cctgtaattc catgagtttg
     8641 tcggcatcgt ttgtttccaa catttgttca gaaatggctt ggctttgact ttctagctct
     8701 tcaatttcag cttctagact ttcgatttgt cgcatgagtt tgcgaacttc tttttgactt
     8761 tctttctggg cctgatagtc attgactgga cttgcttcct ttgcttgatt gctagttgaa
     8821 gcttcctcag tctgactcat ttctgctgtt gctttcttct caacatagta gtcgtaatct
     8881 ccaaggtaga gagttgaacc attctcagac aattccaaaa catgagttgc cacacgattg
     8941 ataaagtaac gatcatgact gacaaaaagc aaggtaccat caaagtcaat caaggcattt
     9001 tctagcactt ccttactatc aatatccaag tggttggtcg gctcatccag aatcaaaaag
     9061 ttattgtttt ccatagacaa tttagctaaa agcaaacgag ctttttcgcc accagatagc
     9121 atgccgactg attttttaac atcatctcct gagaaaagga aggccccaag acggttgcgg
     9181 atttcaactt ctggtgtcag tttgaaatca ttccagagtt catccagcac cgtattactt
     9241 ggtgtcagct tgctttgggt ttggtcatag taaccaacct caacattagc gccaaagcgc
     9301 ttttcacctt tgataaaagg aatctggtcc acaatagact tgataaaggt tgacttgccg
     9361 ataccatttg gaccaacgat agcgacagca ttcatcttac gaagatctag gttgataggt
     9421 tgtgacaaaa cttccccgtc ataaccaata gcagtatttt caacagtcaa aacaacattg
     9481 cccgacgttt tttcagactg gaaggtcatg ttggctgctt tcttgccagc ttcaggcttg
     9541 tccaaacgct ccattttttc tagttgttta cggcgagatt gagcacgttt ggtcgttgaa
     9601 gcacgaacta gattgcgatt gacaaagtct tccagagcag cgatttcctt ctgttgcttt
     9661 tcatagtttt ttgcctcagt agctagcttt tgctccttca actcaacaaa acgagagtaa
     9721 ttccccacat agcgatccaa ggaatacttg gtcaaatcta gcgtaattgt cgcaaccttg
     9781 tccaagaaat aacggtcgtg gctgacgata atgagggcac cgctatagtt taccaagtaa
     9841 ttctctagcc aggagatggt ttcaatatcc aagtggttag ttggctcgtc caagaccaag
     9901 agattgggct tttcaaggag cattttagct agagccaaac gagtattttg accaccagaa
     9961 agctcagcaa ttttcatctg ccacatagac tcgtcaaact tgaatccatt caaaatcgct
    10021 cgaatatcag cttcataggt aaagccacct gcttggcgaa aattttcaga taagcggtca
    10081 taatctgaca tcagtttatc caaatcctca ccagactttt cacccatctc cagctccatc
    10141 tgacgcagtt gtttatctgt ccgacgtaag tcatcaaaga catgaagcat ctcatcatag
    10201 atggtatttt cagactcaaa acggctatct tgagctaggt aagacagaga aatatctttt
    10261 ttcttattga tttctccact agttggctcc tcttctccaa ctaaaatctt caaaagagta
    10321 gacttacctg caccattttt cccaacaagg gcaatccgat ctcgttcatc aacctgcagg
    10381 ttgatattat cgaaaagaac ctctcctgca aaagaacgtt caattttatt agcttgtaaa
    10441 ataatcatac aagtagtata gcatgtttcc ctaaggcatt caagataatc gtaagtcttt
    10501 tagtacaact tttataacat aaaataaact aaattatgta tattttatat tagattcctt
    10561 cactatcttg ttggattttc taaccagcta atcttgtttc aaatagttat cgcacaagcc
    10621 tattatttaa ttcttttcat tatttacgta cgc
//
LOCUS       DAVLAQ010000065        10396 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000065 DAVLAQ010000000
VERSION     DAVLAQ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.065"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..389
                     /locus_tag="VXB71_001746"
                     /pseudo
     CDS             1..389
                     /locus_tag="VXB71_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            475..687
                     /locus_tag="VXB71_001747"
                     /pseudo
     CDS             475..687
                     /locus_tag="VXB71_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            587..1033
                     /locus_tag="VXB71_001748"
     CDS             587..1033
                     /locus_tag="VXB71_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0451825.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VXB71_001749"
     CDS             complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VXB71_001749"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0451826.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2639..3085
                     /locus_tag="VXB71_001750"
     CDS             2639..3085
                     /locus_tag="VXB71_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0451827.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3082..3885)
                     /locus_tag="VXB71_001751"
     CDS             complement(3082..3885)
                     /locus_tag="VXB71_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0451828.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3894..4223)
                     /locus_tag="VXB71_001752"
     CDS             complement(3894..4223)
                     /locus_tag="VXB71_001752"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0451829.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4168..4539)
                     /locus_tag="VXB71_001753"
     CDS             complement(4168..4539)
                     /locus_tag="VXB71_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0451830.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VXB71_001754"
     CDS             complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VXB71_001754"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0451831.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VXB71_001755"
     CDS             complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VXB71_001755"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0451832.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7157..8299)
                     /locus_tag="VXB71_001756"
     CDS             complement(7157..8299)
                     /locus_tag="VXB71_001756"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0451833.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VXB71_001757"
     CDS             complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VXB71_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0451834.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3181 a         2290 c         1826 g         3099 t
ORIGIN      
        1 caccaagtaa aaggaacaaa accaagaaaa gttgatagag atagacttaa aaactatctt
       61 actgacaatc cagacgctta tttgactgaa atagcttctg aatttggctg tcatccaact
      121 accatccact atgcgctcaa agctatgggc tacactcgaa aaaaaagaac cacacctact
      181 atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc
      241 tagcacaggt ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga
      301 tgacgagcga cttttttgaa gcttggtttc agaaatttct cttaccaaca ttaaccgcac
      361 cattggttat tatattaaaa cgaagtaaga ataggacaaa tcgatcagga cagtaaaatc
      421 taattctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactatatta
      481 atggacaatg caagattcca tagaatgggg aagctagaac tcttgtgtga agagtttggg
      541 cataaacttt tacctcttcc tccctactcg cctgagtaca atcttattga gaaaacatgg
      601 gctcatatca aaaagcacct caaaagggta ttaccaagtt gcaatacctt ttatgaggct
      661 cttttgtctt gttcttgttt caattgacta tataaattgt ctaagcgaaa caaccgataa
      721 gaattggcac aaaagcgacc gtatttttgt taccaataca ggaaaaccag ttcatagttc
      781 tatcttgagc aagtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca
      841 tctgtcccct cacatcttca gacacaccac tattagcatc ttatcagaaa ataaaattcc
      901 tttaaaaaca atcacggaca gggttggtca ttccgactct gaagtcacta cttccatcta
      961 cacccacgtc acaaagaaca tgaaagatga agcaatcaat gtactggata aagttatgaa
     1021 aaagattttt taaaaagttt tgtccctttt ttgtcctcta aatacaaaaa tagcccttcg
     1081 gataaaatcc gaggggctag aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg
     1141 gttcgggata aaatagttca ctgaactatt ttatttttta aggttgtaga atgatttcaa
     1201 tccacgatat tcagctactt caccaagttg gtcttcgata cgaagcaatt ggttgtattt
     1261 agcgatgcgg tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac
     1321 tgcaatatca gcgattgttg aatcttcagt ttcacctgaa cggtgtgata caacagcagt
     1381 gtaaccagct tctttagcca tttcgatagc ttcaaaagtt tcagtaagag taccgatttg
     1441 gttaactttg ataaggattg agttagcagc accttcttgg ataccacgtg caaggtagtc
     1501 agtgtttgtt acgaagaagt cgtcaccaac aagttgtact ttcttaccaa gacgttcagt
     1561 aagagctttc caaccatccc agtcgttttc atccatacca tcttcaatag tgatgattgg
     1621 gtatttgtta accaattctt caaggtagtc gatttgttct gcagatgtac gaacagcagc
     1681 accttcacct tcaaatttag tgtagtcgta aactttacgt tctttatcgt agaattctga
     1741 tgaagcacag tcaaatccga taaatacgtc tttacctggt acatatccag cagcttcaat
     1801 cgcagcaagg atagtttcaa caccatcttc agttccttcg aaacgaggag cgaatccacc
     1861 ttcgtcacct acggcagttt ccaaaccacg tgatttaagg attttcttaa gagcgtggaa
     1921 gatttcagca ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg gcaagatcat
     1981 gaactcttgg aaagcgattg gagcgtcaga gtgagaacca ccgttgatga tgttcatcat
     2041 tggagttgga agaactttag tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag
     2101 gtagtcagca gcagcacgag ctacagcgat agacacaccg aggattgcat tcgcacccaa
     2161 tttacctttg ttaggagtac cgtcaagtgc aatcatagca cggtcaatag cttgttgatc
     2221 acgtacatcg tagccaatga tagcttcagc aatgatgttg tttacgttgt caacagcttt
     2281 ttgtgtacca agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg
     2341 ttcaccagta gaagctcctg atggaaccat accacgtccg aaagcacctg attcagtgta
     2401 aacttctact tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc
     2461 agtaataatt gacatttttt actctcctta tgagttaaat tttttacacc tctataatac
     2521 cttaaaaccc ctcctttttc aagaaaaaac gttatctttg tgcaactttt ccttaacttt
     2581 ataaagtaat cgctttcttt tgtctgtttt attctaactt ttatgatata ctgttttcat
     2641 gacagattta tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa taaatccgga
     2701 tgagcaaaga cgctatcttg gtacttttga ggaaagagtt cttggatatg tagatattga
     2761 cacagcaaat agccctcagt tagaaaaagg ctttttattt attttagaaa accttcagga
     2821 aaaagcaaag ccactatttg tgaagatttc accaactatc gaatttgata agcaagtttt
     2881 ctacttaaaa gaagcaaaag aaactgatag tcaagccacc atagtatctg aagagcatat
     2941 tacttctcct tttggcctgg ttattcatag caatgcacca gttcaagtag aagaaaaaga
     3001 ccttcgactt gcttttccaa aactttggga agttaaaaag gaagaaccag ccaaaacatc
     3061 cttatggaag aaatggttta gctaaatctt gcacatattt aataagtgcc caatattggc
     3121 agccgtgcgc tccagataga gactggcatt tttcaaacta tcttctaaag gttcactttt
     3181 ctccaaaata gaaaagacag cttggatatt ttcaaatggt aggggaggta aatcttcagc
     3241 aagactaccg caaatagcaa taacaggaac tccaacaggg gttctttttg caacacctat
     3301 aggcgctttc ccagcaaagc tttgactatc aagtcttcct tctccaacaa caaccaagtc
     3361 agcatctgaa actttcttat caaagttgat taagtccaag caggtatcaa ttccagacac
     3421 gatacttgcc tgagcaaagg cacacaaacc agcagcaatc cccagtcctc catcattact
     3481 ggccgtgcca ccaacaccga tataaatatc tttaatccct ttagaaatga gatggagaat
     3541 caactctcca ataccacaag tttggatttg aagtggattt cgtttctcta gcggaatttt
     3601 tccaagacca accaagtcag ctacttcaaa tagtgccagt tccccttttt gaaaatagcg
     3661 catggcttct ttttgtccaa aagggtctgt cacttggatc catttttctt ttaggtcaag
     3721 agaatgtcgg atagcatcta cagtaccttc tcccccatca ccaacagggc agaggagaca
     3781 ttctacatct gctatcgatt gttggaagcc tctttttatt gcttcagcta cctgttgagc
     3841 tgtcaagctt tccttaaacg aatccggtgc aattacaatc ttcatatttt ccctcattct
     3901 aaacagtcaa tcaaaggaag aacttctaaa aaatccctct tgtcaacatg atgtggtatt
     3961 tcttttttga gcatttcttt ggaacaaaag gcgattccta actccgccga cttcaacatt
     4021 aatagattat taaccccatc accgattgcc accgttcttt ctttagaaag ttttagtttc
     4081 tttctccatt tttccagagt ttcttttttg acctggggac ttataatttg tccaactaat
     4141 tttcctgtta aaagaccttc tttgacttca agctggttgg cagtgaaata ggcaatacca
     4201 agggattttg ctaatctctc caactattgg tgtaaatcca ccagacacca gaccaactag
     4261 gatgccattc ttttggagaa tagagatgaa ctctgggaca tttagcgata gatgaattga
     4321 gttgaagacg ttatcaaaga ccaaaatagg aagaccttcc aacaaggaca ctctttttct
     4381 taaactgctt tcaaagacca actctcctcg cattgctcga cttgtaatct gcgaaatttc
     4441 cgcctcatga cctgcctctc tccctaaaag atcaatcact tcttctagga ttaaggttcc
     4501 atctacatcc aaaacacaca agccttttac ttgagacatc agttctcctc tctaaacagc
     4561 ctaaaaatcg tatgaagtca tcatacgatt ttatctatta attaactaaa ctatggtaca
     4621 agtcaaggta tgacttgcag gctgtatccc atgagaagtc actctccata gcttgttttt
     4681 gtaggtttct ccaaatgtct ggatggtttc tatacaagtc caatgctgtt tggaaagtcc
     4741 aatttaacca ataaggagat agattgtcaa agctaaagcc agtaccgctt ccttcgattg
     4801 gattgaaagc gcgaactgta tctcgcaagc ctccaacttc atggaccaat ggcaaggttc
     4861 cataacgcat agccatcatt tgagacaagc cacacggttc aaaacgactt ggcatgagga
     4921 agaggtcaca agcagcgtag atttcctgag caagtttgac atcaaaagtg atatttgctg
     4981 atagcttgtc tgggtaaatc tgagcaaacc atgagaaagc tccttcaaag gctggatcgc
     5041 cagttcccaa aagaacaatc tgaacatctt cttgcaagat atggtgaaga ctttcgacca
     5101 ccacatcaaa acctttttga cgtgtcaaac gagaaacaat tcccaccagt ggaacgtctg
     5161 ctctaacagg caagccaact ctttcttgca attttgcctt atttttggct ttcccagaca
     5221 aatcttcctg attgaaatga tagtctaaaa gagcatccgt ctgaggatta taaagatcag
     5281 catcaatccc attcacgata ccagatactt taccagactc cattttaaga atctgatcca
     5341 aattacatcc aaactgacta gtcataattt catgagcata gctaggtgaa acggttgaaa
     5401 cacggttcgc atagagaata cctgccttca tccagttcag acagttgttc catcgaaggg
     5461 tgccatcagc gtaacgttca aggccaactc caaacaaatc acccaacatt ccttctgaaa
     5521 attgtccttg gaattctaaa ttatgaatgg ttaaaactgt ttcaatgtcc tcataggctt
     5581 gaatccaaca gtatttttcc ttcaacaaga aaggaatcat agctgtatgg tagtcatgaa
     5641 catggagaag atcaggaata aagtcaatcc tttccatagc ctcaatggca gccagttgga
     5701 aaaaggcaaa gcgttctccg tcatcaaaat caccgtaaac atgaccacgg aagaaataat
     5761 attgattgtc aataaagtag aaggttacac catttaatac tgttttctta attccacaat
     5821 actgtctacg ccaaccaacg ctcacctcaa aatgaagcac atcttcaatc tgatttccaa
     5881 atttagcctc taccatatca tagtagggta aaatcactgc aacttcgtgc ccagctttta
     5941 ccagtgattt tggaagagcg ccaatgacgt ctcccaaacc acctgttttt gaaaagggtg
     6001 caccctctgc tgctacaaat aaaattttca tgaatgaata tcctctgtta ctttagcacc
     6061 tttcttaacc acaactggat gttctgcagt tcctcgaatc acaacaccaa gctcaacttc
     6121 aacccctttg tccaagatag catattcgac ctgagcccct tctccaataa caacacgagg
     6181 gaagagcagg ctatctttaa ccaagctatc cttatggaca tgaatattac gtgatagaac
     6241 agaattagct acttgacctt caataatact accagaggca aactgagaag tgcttacctt
     6301 agatgtatta gcatagtaag ttggctcttc gtttttgacc tttgtataaa tcttttggtt
     6361 tggtgagaaa agagaataga atttttgtga ttcaagcata tcgatattcg cttgataata
     6421 agatttaaca gagtgaatat tggctagata gcccgtgtac tcgtaggcaa aagctccctc
     6481 ttttacagcc aaatcccgta aaacatagcg caatttctct ggatgttctt ttttagcttc
     6541 ttcttccaag tgttcaatca accaaggtgt atcaacgaca aagatatctg tagacatatt
     6601 gaacgtttca gctgttgact tgctatcaaa gagtttatga gaaagaacat ggtctgtttc
     6661 atctacatcc aagattgcat ttacttctga aatatctttc ttagctagtt ttttataaac
     6721 tacagtgata ggctcttttg ttgtactatg taggtggaaa acttggttca aatcaatgtt
     6781 aataagaaca tcgcagttga gggcaaccgt ttggtttgag ccagaacgtt tcaaataagt
     6841 aagaagctgt tggtagtatt cttttccaac tgtactactt tctacacggg tattgtaaat
     6901 tcctagatag taatggctaa gaagggttga taagccccac tcgcgccctg aacgaatatg
     6961 gtcaaagact gagctgatat tatcctgctg gaaaatacca aagacactac gaacacctgc
     7021 attagcaagg cttgaaagtg ggaagtcaat caaacgatat ttcccaccaa atggcaaact
     7081 tgctactgga cggtggtccg tcaatgtcga catatcgtga aaaccaactg tatttcctaa
     7141 aatggcagaa tatttatcaa tcttcatctg ttgctacccc cactacttca ttatatccta
     7201 caacttgtac ttcatctgtt ccatcaattt cgacaccgtc agaaataatc gcaccttcac
     7261 caataatggc acgtttaatc ttagctcctt gaccaatgat agctccactc atgataactg
     7321 aatcaaggac ttccgctcct tcgcgaactt gcgcgcctgt tgaaaggata gaatgtttaa
     7381 cagttccatc aacgaaacat ccgtctacaa ctaatgagtc ttccacatga gcatttgccc
     7441 cgaggaagtt tggtggtgaa atcaagtttc ttgagtaaat cttccattga cggttacgac
     7501 tatccaaggc attttctgga gaaatatact ccatgttcgc ttcccaaagt gactcaatag
     7561 taccaacatc tttccaataa ccactaaatt cataagcata aacactttca cctgactcaa
     7621 ggtaatttgg aatgacattt ttaccaaagt ctgacatgcc aaccttgctc ttttcagcag
     7681 cgactaacat attacgaagg cgttgccaat caaaaatgta gattcccata gaagcttttg
     7741 tagatttagg ttgagctggt ttttcttcaa attcaacaat acgattgtta gcatctgtgt
     7801 tcatgatacc aaaacggctt gcttctttaa gagggacgtc taaaactgct actgtcaagc
     7861 tggcattatt atccttatga gactggagca tatcatcata gtccattttg tagatgtgat
     7921 ccccagacaa aatcaagaca tactcaggat tgacactgtc gatatagtcg atattttggt
     7981 aaatagcgtg actagtcccc tcaaaccaac gatttccttc acttgcagaa taaggttgaa
     8041 gaatagagac acctgaatta ataccgtcta gtccccagct tgaaccattc ccaatatggt
     8101 tgttgagagc aagtggttga tactgtgtaa cgaccccaac attatgaatc cctgagttgg
     8161 cacagtttga tagggcaaag tcaatgatac ggtagcgccc accaaattgc acagctggtt
     8221 ttgcgatgct ttgagtgagt ttaccgagac gagttccttg cccaccagca agaatcaaag
     8281 ctaacatttc atttttcatt ttctactcct ttttggtttt tatttgtgac ggttttagta
     8341 gatttcaagc gacgtttgat tttccataca cttgctccca tagccggtag ggtaaaggtt
     8401 aaggtctgct cataatcttt ccatagtcct tcttgcgttt gaacagtttg attatgttct
     8461 ttccaaacgc ctccccactc ttccaactca gtattccata cttcttcgta aattcctgca
     8521 acgggtagtc cgattgtaaa atctttccgc tcaacaggta ccatgttaaa gatacagact
     8581 aacatttctc cctttttacc cttacgaata aaggaaagaa cactctggtc tcgattatcc
     8641 gcatcaatga tttcaatacc atcatagctg gtatcgattt cccacagaca gcgatgatct
     8701 ttgtaaaact ggtttagctg agaagtgaaa tacttcatct tagcattcat tgggtcttct
     8761 aggttagacc attccaactg ttcttcagat ttccattcta ggaattgacc gtattcgcta
     8821 cccatgaaga gcaatttctt accaggatga caaatttggt acgtatagag attgcgcaag
     8881 cctgcgaatt gattgtaacg atctccccac atcttatgca tcatactctt cttgccatga
     8941 accacttcat cgtgcgagaa tggcaagaga taattctcct tgaaaacata cataaagctg
     9001 aaagtcacca ggttaaagtc atatttacga tagatcggat cttcttcgta gaaacggagg
     9061 atatcattca tccagcccat gttccatttg tagtcaaatc ctagaccacc aatctctttc
     9121 attcccgtaa tcttggtcgc agacgaactt tcttctgcaa tcatcatcac atctggatat
     9181 tctaacttaa taacctcatt caagcgctga aggaaataat aaccttcata gttgagattt
     9241 ccgccatctt tattaggtgt ccatggagca tcatcatagt ccaaatagag catgttgcta
     9301 acagcatcca cacgaatacc atccaaatga tagacatcaa tccaatgctt aatgcaagaa
     9361 attaagaagg actggacttc attttttcca aggtcaaaat taagggcacc ccaaccatgg
     9421 ttatgagcct tattatggtc ttggtattca aaagtcggtg tcccatcata ataggctaag
     9481 gcatcatcgt tgatggtaaa gtgacctggt acccagtcca caataacccc aatattatgg
     9541 gtatgacact cctcgacaaa atcttgaaac tcctctggtc ggccataagc atgctctaaa
     9601 gcgaagtaac ccataagctg atacccccaa ctcaagccca aaggatggga catcaagggc
     9661 ataaactcaa tatgagtata gttcatttca acgagataag gaatgagttc atccttgagc
     9721 tgggcaaaac tataaggact gccatcagaa tttcttttcc atgatccagc gtgaacttca
     9781 taaatattga caggacgctc ttcaaagccc caacgttttc ttcgtgccag ccaaagtcca
     9841 tccttccatt tcttctcacg aagctctgtt aagattgccc ctgttcctgg acgagcctca
     9901 tacctgacag caaaagggtc aatcttcatc agttgatgac cattttgacg tgtgacatga
     9961 tatttgtaaa tatgcccttc ttgagccata ttggtaaaga cttcccagac cccaaaatca
    10021 tttcttacca ttggaatctg attttcaatc cagttggtaa aatcaccaac caagtgaaca
    10081 gcctgagcat taggtgccca aacacggaag gtatagccat gctctccatt tagttcttcc
    10141 ctatgtgctc ctagataatg ttggagataa aaattttcac ccgtcataaa ggtttttaat
    10201 gcttctctat tatccatata ctccccttct cctgtaagcg ttttctatgt ttttattata
    10261 ctaccttttt agagaagatt caagtaaatt actatacttc tttaattatt ttgaaaatct
    10321 acaacaagtt cacttactcg ttcaattgta aatcaatatt ttttcaaaaa attgcgaaaa
    10381 ctcctttctt tttcta
//
LOCUS       DAVLAQ010000066        10264 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000066 DAVLAQ010000000
VERSION     DAVLAQ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.066"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="VXB71_001758"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="VXB71_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0451835.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1317..2021
                     /locus_tag="VXB71_001759"
     CDS             1317..2021
                     /locus_tag="VXB71_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0451836.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="VXB71_001760"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="VXB71_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0451837.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="VXB71_001761"
     CDS             3365..4174
                     /locus_tag="VXB71_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0451838.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /locus_tag="VXB71_001762"
     CDS             4265..4507
                     /locus_tag="VXB71_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0451839.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="VXB71_001763"
     CDS             4509..4763
                     /locus_tag="VXB71_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0451840.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5505
                     /locus_tag="VXB71_001764"
     CDS             4810..5505
                     /locus_tag="VXB71_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV0451841.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(5854..6840)
                     /locus_tag="VXB71_001765"
     CDS             complement(5854..6840)
                     /locus_tag="VXB71_001765"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0451842.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7034..9502
                     /gene="gyrA"
                     /locus_tag="VXB71_001766"
     CDS             7034..9502
                     /gene="gyrA"
                     /locus_tag="VXB71_001766"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0451843.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9502..10245
                     /gene="srtA"
                     /locus_tag="VXB71_001767"
     CDS             9502..10245
                     /gene="srtA"
                     /locus_tag="VXB71_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0451844.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3185 a         1747 c         2289 g         3043 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggccccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaaggtccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt cgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattaaag ctgagtaata acaatataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggttattt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgac tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttgaccattc tccctttaaa tgctattttt acagtgtttc gattaggacg tatcttccgc
     5101 ttagcaaggc tgacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaactag aaagaaaaat tagtagattc ttacgaacaa atggattgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgctaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actcaaagac gaattatcga gctaaagaat attaatagag
     5521 aaacaatctg aaaaaatcga agaactacat tgaatgataa aagacttagt tgaaaaaata
     5581 tcataaaggt gagacaaaat aaaacttgat tcgaggagaa atcaagtaag ttttgacaca
     5641 atagaacgca tattatcagg tataaaaact tgatactatg cgttttatag agaaataaaa
     5701 taaaatctga acaaatcaat taggaattta aagcatttta taacaacgtt ttagagtaat
     5761 ggggtgctat ttcaacttca acctactata atacagaaaa aaatacagaa aaaaacaact
     5821 ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc
     5881 tggatttttc catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt
     5941 ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac
     6001 aacagctggt tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga
     6061 aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac
     6121 tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac
     6181 accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc
     6241 ttcaaggttt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg
     6301 ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc
     6361 ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa
     6421 accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa
     6481 gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt
     6541 tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac
     6601 aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt
     6661 gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg
     6721 aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga
     6781 tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat
     6841 tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt cattctatca
     6901 cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt
     6961 ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat
     7021 gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa
     7081 ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg
     7141 agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac
     7201 cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca
     7261 cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta
     7321 ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc
     7381 cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat
     7441 caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt
     7501 cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg cggttgggat
     7561 ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat
     7621 ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc
     7681 aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg
     7741 ttcgattgtc ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat
     7801 cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg
     7861 cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga
     7921 aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa
     7981 cctcttcaaa atgacccaaa tgcaaaccaa ttttggattc aatatgctcg ctatccaaaa
     8041 tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatattg agcaccaaaa
     8101 agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat
     8161 cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc
     8221 tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg
     8281 tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa
     8341 gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc
     8401 taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt
     8461 ttctgataaa cgccgtacag agttgatggt tggacagatc ttgagtctcg aggatgagga
     8521 cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt
     8581 ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt
     8641 gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt
     8701 cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg
     8761 gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagatg aaagtattca
     8821 gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg
     8881 tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct
     8941 caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttga cagaaggaga
     9001 tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt
     9061 tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac
     9121 agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg
     9181 atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat
     9241 gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg
     9301 ggatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa
     9361 tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc
     9421 tcagatagtg actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa
     9481 cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa
     9541 aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt
     9601 aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag
     9661 gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct
     9721 gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca
     9781 gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt
     9841 gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa
     9901 ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta
     9961 ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa
    10021 gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt
    10081 gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca
    10141 gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat
    10201 gaaattctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa
    10261 tcat
//
LOCUS       DAVLAQ010000067         9772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000067 DAVLAQ010000000
VERSION     DAVLAQ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.067"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(162..1925)
                     /locus_tag="VXB71_001768"
     CDS             complement(162..1925)
                     /locus_tag="VXB71_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0451845.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(1934..2524)
                     /locus_tag="VXB71_001769"
     CDS             complement(1934..2524)
                     /locus_tag="VXB71_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0451846.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VXB71_001770"
     CDS             complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VXB71_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0451847.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3190..3882)
                     /locus_tag="VXB71_001771"
     CDS             complement(3190..3882)
                     /locus_tag="VXB71_001771"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0451848.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(3899..4213)
                     /locus_tag="VXB71_001772"
     CDS             complement(3899..4213)
                     /locus_tag="VXB71_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0451849.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4225..4770)
                     /locus_tag="VXB71_001773"
     CDS             complement(4225..4770)
                     /locus_tag="VXB71_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0451850.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VXB71_001774"
     CDS             complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VXB71_001774"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0451851.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            6303..7103
                     /locus_tag="VXB71_001775"
     CDS             6303..7103
                     /locus_tag="VXB71_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0451852.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7198..8040
                     /locus_tag="VXB71_001776"
     CDS             7198..8040
                     /locus_tag="VXB71_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0451853.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8040..8522
                     /locus_tag="VXB71_001777"
     CDS             8040..8522
                     /locus_tag="VXB71_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0451854.1"
                     /translation="MAKKVKIKKTLAEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8522..9142
                     /locus_tag="VXB71_001778"
     CDS             8522..9142
                     /locus_tag="VXB71_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0451855.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9396..9491)
                     /locus_tag="VXB71_001779"
                     /pseudo
     CDS             complement(9396..9491)
                     /locus_tag="VXB71_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2984 a         2075 c         1691 g         3022 t
ORIGIN      
        1 agaagttata gtgtagcatt ccaacttcaa agcactataa agtaaattga aacaagaaca
       61 atacaaacaa ttctcgtaaa cggattgcaa ccacaaaaaa gcaagcattc acaagaatac
      121 ttacctatca tgggaggaac aaccgttcct cttttttatt actaaaattc aaagaattcc
      181 aatgcttttt tcaagagcaa atccgtatat tctggatctt cttgggctac ttctatttcc
      241 cgctgaactt tttccaaatc atctgtaatc actccatcta ctcctaagtg aagagatttg
      301 ctgatagctt ctgaatcatt gacagtccag acataaagtt tctgatccgt tgtccatagt
      361 ttgcttacaa aatattcatc caaggttgag tactccatag tatatcctgt cgctcttgtt
      421 ttaggaaaga cagaattgta gggcatgatg aaataaactg gcagttcggc atcatactgt
      481 cttacttttt cgacaacatg gtagtctaaa gactggattt gatgtccata aatcttgagc
      541 tttgcagcat aacgggctaa aaagcggttc atcatgtctg gactatcttt tttactggtt
      601 ttaatttcaa ttagtaattt ttgaccaagt tcgttggctc gactgagata atcttcaaag
      661 cttgaaattt tagtctggta gccattttca aaaatatcaa tccctttaag ctcctccaag
      721 tttaagtctt gaggactttt attgatacct gctagatttt tcaagttagc atcatgcatc
      781 atgacaaact gcccatcttt tgtttcctgc acgtccgtct ccaccaagtc tggtttgagt
      841 tgtgctgtag tttccaagga ctctactgta ttttgaatcc catttgcatt ggaaacccct
      901 cggtgagaaa taagttgagg tagatgaacc atgggagcct ccagataaat ataaccttct
      961 aaggcaaaga aaaaactggc acaagtcatg acaccccatc gcacgatgtg atctttttct
     1021 ctcctaggaa gcatatccag ctcctttcct gtcaaaaatg aaacaaattt aaccaaaaaa
     1081 taagtcagag ccatataata gagattttta atcacgacaa aattcaaaat accaagaatc
     1141 agagactctc tctgagtgat atcatctacc aaagtttgag ccaataataa aggaatcaaa
     1201 ggaagataaa ataataaatg tgctttgagc aagatgtaaa ataaattcca agcataaaaa
     1261 gtaactctct tcttggtttt ctccaagcta aacatcactg cttctcgaac agtcagctga
     1321 tcatatacaa tcttcggaag ggcaaacatc aatctgacag agacatagag aaagataaga
     1381 gatagaagta ggatgctcag ccaccacatc caatatttat cttctaaata agcttggata
     1441 aactctggaa tgacgatttt attaagataa taaatcttca gcattttccg tataaaagga
     1501 aacagcatag ctatatagaa aaagataaac aaggctttag cgccagttag ctttttcata
     1561 aattcaaaac tttcatggaa aaccttgcgg atatactcaa ttagccttcg cttttcatta
     1621 tagaggagat gacgagcacc aataaagagg agtcctattt gaaaataagc aaccagaaag
     1681 ttaattacaa tcaaggctaa aaaagctaga ctaatcaatg gagaatgagt aaggatggct
     1741 aagacattgt tataggaaat aaaaagataa cctgtctgat ctaataagaa gctagccaac
     1801 catgaattga atggtaccca caaatactcc actatcataa aaatcaagaa aaatagaaag
     1861 aggattttat caagattgag gtaaatctgt ttaagaccca attttttagg tttttcaggt
     1921 ttcataggca ctcctagtca aataattgag acaagtccaa gccaccaaaa ggattgtttg
     1981 ataagctact ttctgtctct aacaattccc tagcttgatc cgactctaag aaggattcgt
     2041 aaacacgcgc cgtcatccga gcatcctcta aactattatg agactgacct tgaaatccaa
     2101 gaaatgaggc aacagtttgc aatttgagat tggcaatacc atgtaaatct gaactccgac
     2161 gttcaaaagc ttcatcatac aaatccacct tgtactgttg gctatagtct aaaccatgct
     2221 ctgctaaaat aggtaaatca cttttagcag cattgtagcc tatcatcagc aaagaaccca
     2281 caaactcttg gaattcttct aagactttct caactggagg agcatctttt aaggtctcag
     2341 ctgtaatccc ggtcaaacca ttgataaagc tttttagagg gacgctggta tgaacatagg
     2401 aatcataggc atcgatttcc cgaccatctc taaaacgcac tgccgatact tgaatcaagt
     2461 gtgtttgtcc ttcgtgctga ttaaattcta aatcaaaagc aatgtaatct tctaatcgtt
     2521 ccattctgta cctctcctct actgtctctg ttctaatcaa ctatactatt cacaaacaaa
     2581 agaagccatc aggttagcat ttaacctaaa cagctccttg attatcctcc aaataaacga
     2641 gcaaaaaagc cttttttagt ggattggact tcttcttttg cttggtccag ctctagctta
     2701 agattttctt gatccttcat ggcttgaagg gtcaattgtt gttgctgatc taattgtttg
     2761 tctttctcag caatctgacg gtctttgata cgcatctgct cgtctttttc tgataactga
     2821 cgatccttgg cttttaattg ttcataaaga cgaagaattt ctgcattctt ctcatccact
     2881 agaatctcca tcagttcacg ttgtttgaca tcttcactga caggttcatc ttcaaaaatc
     2941 gtttttttat agatttcttc tagcttaatc aagccacttc tggtaacaac tgttacccct
     3001 ttgtcatttt tatctgtgtc ttcttctggt aattctttga cacggttatt gattgcttgg
     3061 cgagataatc ctaagacctc tgcaatctca ctgacggtca tttcaatact cataatatcc
     3121 tctgaaacgt tttctagctt ttctttactt aaatcttatc ataagctaga aaaactgtca
     3181 aatttccgct taatctaaag ccttcaaaaa ggccaacaag acttgggcag agcgacgtcc
     3241 agcttcgata ataaactcat caaaaaagat gtttgcttca tggttggcat tgtcactcat
     3301 agctcggatg actaagactg ggagattgag ggtatgcgct gcttgagcaa tagctgcccc
     3361 ctccatctcc acggctaaaa cttctgggaa atgggactta atcgcttcta tcttgtcatt
     3421 tcctgcaaca aaactatctc ctgtagcaat caaaccaaga tgccagtttt ggtccaattg
     3481 agataaactc tcttggattt gagcaacaaa ggttttgtct gattcgaaat aaagcggttg
     3541 ttgcgccatt tgtccataag catagccaaa agctgtgaca tccacgtcat gataggctaa
     3601 tttgtcagca atcacgacat ccccaacagc gataccttct gctactgccc cagctgaacc
     3661 cgtattaata agggcatcca cctggaaatg atcagccaaa atcgccacac tcatagcaga
     3721 catgacctta ccaattccac tttctacaag aacgacttca tgagaagcaa tggttcctgt
     3781 atgataggta ttccccaaaa caacttgctc ctggacatta tataaatgct ggaccagata
     3841 agccagttct tctggcatag cagcaataat tcctattttc atttcaattc cttttctatt
     3901 acaaaagttt cattgctaaa acaagcaaaa tcaagagaaa gatgaccgcg aataagattt
     3961 tattcaactt agaattgaag acatttctct tggtattttc aatgcgacgg cttttatgaa
     4021 tagatggttc gacctgaatc ttcaaggttt cctggctaaa accatgattc ttaggattgg
     4081 cataaccaaa acgggaagaa gaggttggta aaatcttagt ctcctcatta tcatctagca
     4141 aaggaggacc tgaaattttt tcgcctctat tagctctttc aatcatttca tccgttaata
     4201 aagatttacc catactgacc tcctctattt tttctgcaac tcccaatact gaacagccat
     4261 aattgtcttg gcatcacaaa tatgacctga ttggattaat tctttcgctt cttctaagct
     4321 cacttcaagg acttccaagg tttcatcctc atcctgcgga cgcggatttt ccacttttgt
     4381 caaatcgctt gctaaatata gttttaactt ctcattacaa aagccaatag ctgaataaaa
     4441 atcgtacaag agttctaatt tccctgtata ggctgtttct tcctctaatt cacgaagggc
     4501 agctgccaca ggggctgtgt tttctcctac ttccaatttt ccggctggaa tttcgtaaga
     4561 gacagcctcg atagctttgc ggtactgctt gaccaagatc agtttttgtt catccgttac
     4621 tgctaaaaca cagacagccc cattgtggaa aatcaaatcc cgttgggcag ttcccttgcc
     4681 ttctggtaat tcaacctgat cttggaccag tttaaatatt ggtccttgat agatttcttt
     4741 tcggctaagc gttttttctt caaactccat gataggctcc tactggttct taggatgatg
     4801 aggaagacgt gttgcatatt cgtctttatt gatctgacga ccgcgaccaa tagcaatagc
     4861 atctgctggc acgtctttag taatagttga accagcacca acgagggaat tgtcaccaag
     4921 ttctactggt gcaataatgg ttgaatttga accaacaaag acattgtctc caatgactgt
     4981 cttgtatttg tttttgccgt cataattgac tgtaatagtt ccagcaccga aattaacgtt
     5041 gcttcccact tcacagtttc cgatataagt caaatgacca gccttggtat tctcaccgat
     5101 tgaagatcct ttcacctcaa caaagttacc aatatgaact tgggcaccca gacttgaatt
     5161 tggacgaatg tgagcataag gaccgactgt cacaccgtct gcaacactac tttcctcaat
     5221 catagaattg gtaatgaccg ctcctgctcc gatagtgctg tccactacat aagtaccgtt
     5281 tgtcaaaaca gtctcagcac caattttcgt ttgccctttc aaggtaacat tggcttcgat
     5341 ttgaacttcc ggagcaatct caacatcaat atcgatataa gttgcttctg gattgacaaa
     5401 gctaacaccg ttgaccatat gtttatgatt gatgcgacga cgcataactg actcagctgt
     5461 cgcaagcgcc acacggtcat ttaccccaag actttcatca aaatctttca aagtataagc
     5521 gccaactttt tcaccagttt cacggaaaat accaatgacg tctgtaatat agtattcgcc
     5581 ttgagcgtta ttggtattga tatttttcaa agcctcaaac aaacgctcgt tgtcaaagac
     5641 gtatgttcca gtgttgattt ccttgatttg cttttcaaaa tctgtagcat ccttctgctc
     5701 aacaatacga agaacctcag cattgtcatt acgaacaatt cgtccatagc caaaaggatt
     5761 atccgtttca gcagtcaaga tagtggccac atttttatga ttgatatgga aatcaatcaa
     5821 gtttttcaag ctttcaccag tgattaaagg agtatctcct gcaatgacca aggtgtgtcc
     5881 tgacaaacct tctaagatag gttctgtcat cataactgca tgaccagttc ccaactgttc
     5941 agattgagtc acaaattctg tctgtccagc caagacctcc tcaaccaatt ctgccttgtg
     6001 tcctacaact gttactgtct tttcaggttg gatagctccc acactacgga aaacatgttc
     6061 caacatagaa atacccgcaa ccttgtgcaa aacttttggc aaatcagatt tcatgcgagt
     6121 ccctttaccc gctgctaaaa taatggcaaa atttgacata atcttctctt ttctgtagaa
     6181 attccctttt attataccat atttcaaatc attccgcact cttgaatgaa aaaatgctct
     6241 aaagtctctt ccttaaccca tttttttgat tttttttgat ttttagggta gaattataag
     6301 atatgagaaa acaaattcat ccacttattt tatttagttt tttggggatt atgatgttca
     6361 ttttaatcat caatcgccca cttaatgaca accaatcgtt taaaacaaaa tccaatatag
     6421 cacagattga agcacaggct ttgaaacact tagacaaacc gattattgac ctctctggct
     6481 ggcagcgtcc tgaagaaatc aactacgatg ccctctcaca aaatatttca ggtgctattg
     6541 ttcgtgttca cagtggtgct caaacgacaa aagaaaatga tgcttcattt atcaatggaa
     6601 tagacaaggc ctataagagt catatcactg aacttcaaaa gcggaatgtc ccagttgctg
     6661 tctacgctta tgtagctgga aaaagtgtcc aagaaatgga aaaggctgcc gaagttttct
     6721 acaatgctgc ctctccttac agccctagtt actattggct tgacgtggaa gacaaaacca
     6781 tgtctaatat gaacgaaggt gtcgaaaact ttcgagcaaa actagcatca ctaggtgcta
     6841 aaaacatcgg catctacgtt ggtgtctact tcatggaaga acacagtatt gatacaggca
     6901 agtttacctc tgtttggatt ccgtcctacg gctcagactc aggatttttg gagagcagtc
     6961 ctaaaactga tttagattat gatattcacc aatacacatc taaaggaaaa attgccggct
     7021 ttgaccacga tttagatatc aacgttatct ctcccttaaa aaataaagaa gaaacctttc
     7081 gaaaactttt tttaaaacct taaaagcatt tgtttatcat ttgctttttc tttttgtgtc
     7141 tgattgtgat acaatatagt aaggattttt tgaaatagaa atagttggag gaaatatatg
     7201 ctctcatggt tagcacgcgt tattaaaggg attgtaattg ctcttggatt tatcctaccg
     7261 ggaatttccg gaggggttct agcagcaatc ttaggaatct atgaacgaat gattggcttt
     7321 ctggcccatc cctttaaaga ctttaaagaa aatgttttgt actttattcc agttgccatc
     7381 ggtatgcttc tgggaatcgg cttattttcc tacccgattg aatacctgct tgaaaattat
     7441 caggtttttg tattatggag ctttgcggga gctattatcg gtacagttcc tagcctcctc
     7501 aaagaatcaa ctcgagaatc tgaccgagac aagattgatt tagcttggtt atggacaacc
     7561 tttatcattt ctggattagg actctatgcc ttaaattttg tcgttggaac cttaagcgcc
     7621 agctttctta acttcgtcct agcaggcgca ctattggccc ttggcgtctt ggttcctggc
     7681 ctcagcccat caaatttact tttgattttg ggactctatg ctcctatgtt gactggtttt
     7741 aaaacttttg atttcttggg aaccttcttt ccgattggaa ttggtgcagg tgcaactctc
     7801 atcgtttttt caaaattgat ggattatgcc ttaaacaact accactcacg tgtctatcat
     7861 ttcatcatcg gtatcgtcct atcaagtacc cttttgatct taattccaaa tgcaggaaac
     7921 gctgaaagta tccaatacac aggactttca cttgtcggtt atgtcatcat cgccttcttc
     7981 tttgcgctgg gaatctggct tggtatttgg atgagtcaat tggaggataa atataaataa
     8041 tggcaaaaaa agttaaaatc aaaaaaacat tggcggaaca aatcctatct aaagcagcta
     8101 tccctcatca ggggattcaa atcaatgccc tagaaggaga gcttcctcaa ggttatgaac
     8161 gagatcagat tttcaaaacc ttggcgcttt tgggagacaa gaccggaccg attatcggaa
     8221 ttgtccctat cactcagcac ttgtctgaaa agaaactagc taaaatttct ggcaataaaa
     8281 aagtgagcat gattccacaa aaggacttag aaaaaacaac tggttacatt catggagcca
     8341 ataatcctgt cggaattcgt cagaaacaca attatcccat ttttatcgat aaaattgctc
     8401 tagatttgga tcaaatgatt gtctctgcag gcgaagtcgg acacagcatt atcgtcgcgc
     8461 cacaagactt ggctagcttt gtaaaggcag actttgtaga tattttggag gacatcaagt
     8521 aatgaaactc tactttgtcc gccacggtcg taccctctgg aaccaagaag gtcgttttca
     8581 aggtgctagt ggtgattctc ctcttcttcc tgaatccatt gaaaccctaa aacgacttgg
     8641 tcagtatctc aaggaaattc cttttgatca gatttattca agtgatttac ctcgagcggt
     8701 caaatctgct gagattatcc aaagtcaact ctataccccc tgttctttag aaatcgttcc
     8761 taatctccgt gaatggcaac ttgggaagtt agaaggtttg aaaattgcaa ccttggaagc
     8821 tatttacccg caacaaatcc aggcttttcg ttcaaatctt gctcaatttg acactcgaat
     8881 gttcggagcc gaatccctct atagtacaac tcaacggacc atccaattta tcaaatcatt
     8941 aaaagatagt ccagctgaac gtattctaat tgtcggacac ggcgccaatc ttactgccag
     9001 tcttcgtact ctcctaggct ataaagaacc acttcttcgt aaagatggcg gtctagcaaa
     9061 tgccagcctg accattatag aaacccatga ttttgaaaca ttcactctca atacttggaa
     9121 tgatacttct tatcaatcat aattatagcc tagccttctg aactagaacc ataggagata
     9181 tagtcagttg aaacaaaaat aagataaaag agcctcgtaa aaaggtattg caacttgcca
     9241 ataccttttt tgatatgaac acgtgtcttc tcaacaggat tgtagagcaa aatgaaataa
     9301 gaactgaata atatgatttg agaatttaaa tcaatttata agaatgtttt agaagcagtt
     9361 atgtactatt ttagattcac ttttctatac taagatgagt agggaggaaa aggtaaaagt
     9421 ttatgcccaa actcttcaca taagaactct agcttaccca ttctatggaa tcttgcatta
     9481 tccattaaaa cttccagact catacccttc taaaatctat tcaaaccacg tcagcttcac
     9541 attatatatg ttggttacct cacaagtttt atctgcaacc tcaaagctgt tctttgagca
     9601 gcctacagct agcttcctag tttaatcttt gcttttcact gagtatcaag ttaaaaaatg
     9661 aggctggtca aaaagtcttt aaaataaaaa aaacgcatat tatcaggtgt taaatgaact
     9721 gcaccccaaa agttagacag aaaaaatcta acttttggag tgtttttatt at
//
LOCUS       DAVLAQ010000068         9741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000068 DAVLAQ010000000
VERSION     DAVLAQ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.068"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            117..3218
                     /locus_tag="VXB71_001780"
     CDS             117..3218
                     /locus_tag="VXB71_001780"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0451856.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3301..4308
                     /gene="pfkA"
                     /locus_tag="VXB71_001781"
     CDS             3301..4308
                     /gene="pfkA"
                     /locus_tag="VXB71_001781"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0451857.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4367..5872
                     /gene="pyk"
                     /locus_tag="VXB71_001782"
     CDS             4367..5872
                     /gene="pyk"
                     /locus_tag="VXB71_001782"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0451858.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6607..6832)
                     /locus_tag="VXB71_001783"
                     /pseudo
     CDS             complement(6607..6832)
                     /locus_tag="VXB71_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7680..8552
                     /locus_tag="VXB71_001784"
     CDS             7680..8552
                     /locus_tag="VXB71_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0451859.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8698..9042)
                     /locus_tag="VXB71_001785"
                     /pseudo
     CDS             complement(8698..9042)
                     /locus_tag="VXB71_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9185..9497
                     /locus_tag="VXB71_001786"
                     /pseudo
     CDS             9185..9497
                     /locus_tag="VXB71_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9501..9741
                     /locus_tag="VXB71_001787"
                     /pseudo
     CDS             9501..9741
                     /locus_tag="VXB71_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
BASE COUNT         3018 a         1688 c         2071 g         2964 t
ORIGIN      
        1 caaaaataca aatgaataga aaataaatta gtaagctgat gaaatttttc tcaagagaag
       61 ccatttatag gtgaaaatgg tataatatag tgagaaggat agaggagaag tgtaaattga
      121 tcgcacaact agatacaaaa acagtctata gttttatgga aagcgtcatt tcgatcgaaa
      181 agtatgtgag agcagctaaa gaatacggct acactcattt ggctatgatg gatattgaca
      241 atctttatgg cgctttcgac tttctagaga ttacaaaaaa atacggcatt catcctttgc
      301 tagggcttga aatgacagtg tttgtagatg atcaggaagt gaatttgcgc tttttagctc
      361 tatctagtgt gggctatcag cagttgatga agctttcgac agccaagatg cagggggaga
      421 aaacttggtc agtcctgtcc cagtacctgg aggatatcgc ggtcattgtg tcttattttg
      481 atagagttga gtcgttagaa ctaggctgtg attactatat aggggtttat ccagaaacac
      541 tagcaagcga atttcatcat cctatcttac ctctttatcg ggtcaacgct tttgaaagca
      601 gggatagaga agttcttcaa gttttaacag cgattaaaga aaatctaccg ctcagagaag
      661 ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag ttctttagag aaactattcc
      721 aagagcgttt tccgcaagct ttggacaatt tagaaaagct tatttcaggc atttcttacg
      781 acttggatac tagtctgaaa ctgcctcgtt ttaatccagc tagaccagca gtagaggagt
      841 tgagagagcg tgctgaactg gggcttgttc agaaggggtt gactagtaaa gaatatcaag
      901 atagactaga ccaagaattg tctgttattc atgatatggg ctttgatgat tatttcttgg
      961 ttgtttggga tttgttgcgt tttggacgat cgaatggcta ttatatggga atgggaaggg
     1021 gttctgcagt aggcagtttg gtttcttatg ccttagacat cacggggatt gacccagtag
     1081 agaaaaatct gatttttgaa cgctttctta atcgtgaacg ctataccatg cctgatattg
     1141 atattgatat cccagatatt tatcgtccag attttatcag atatgttggt aataaatatg
     1201 gtagtaaaca tgcggcacaa atcgttactt tttcaacctt tggagccaag caagctcttc
     1261 gagatgtctt gaaacgcttt ggtgtgccag agtatgaatt atctgcaatt actaagaaaa
     1321 tcagttttcg tgacaatctt aagtcggcct atgagggcaa tctccagttt cgtcagcaaa
     1381 tcaatagtaa gttagaatac caaaaagctt ttgagattgc ttgcaagata gagggctatc
     1441 caaggcaaac ctctgtccat gcggctggtg ttgtaattag tgaccaagat ttaaccaact
     1501 acattcctct aaagtatggt gatgaaattc cactgactca gtatgatgct catggagttg
     1561 aggctagcgg acttttgaag atggactttc tgggactacg aaatttgacc tttgtccaga
     1621 agatgcaaga gttgcttgct gaaacagaag gtattcatct gaaaattgaa gaaatcgatt
     1681 tagaagacaa agaaacgtta gctttatttg cctctggtaa tacaaaaggt atctttcaat
     1741 ttgagcaacc aggtgccatt cgtctgctta agcgtgtgca accagtctgt tttgaagatg
     1801 tcgtcgcgac tacttctcta aatcgaccag gtgcaagtga ctacatcaat aattttgtgg
     1861 caaggaagca tgggcaggaa gaagtgactg ttctagattc agctctggag gatattttgg
     1921 ctccaactta tggcattatg ctctatcagg agcaggttat gcaggttgct cagcgatttg
     1981 ctggatttag tcttgggaag gccgatattt tgcgtcgagc tatgggtaaa aaggatgcct
     2041 ctgctatgca tgagatgagg gcttccttta ttcaaggctc catagaagca ggccatactg
     2101 cggaaaaagc agagcaggtt tttgatgtta tggagaagtt tgcaggttat ggatttaata
     2161 gatctcatgc ctacgcctac tcagccttgg ccttccagtt ggcttatttc aaaacgcatt
     2221 atccagccat tttttatcag gtcatgttaa attattccaa cagtgattac ttaatagatg
     2281 cacttgaagc aggttttgaa gtagcctctc tatccatcaa tactattccc tatcacgata
     2341 aaattgccaa caagtctatc tatataggtt tgaaatcgat taaggggctc agcaaggact
     2401 tggcgctttg gattattgaa catagacctt attctaacat tgaagatttt atagctaaat
     2461 tacctgagaa ttatctgaaa cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg
     2521 attcatttga aaaaaatcgt caaaaagtat ttaataactt agctaatcta tttgaatttg
     2581 tgaaagagtt gggaagtttg tttggagatg ctatttatag ttggcaggaa tcggaagatt
     2641 ggacggaaca agaaaaattt tatatggaac aagagctttt agggataggt gtcagcaaac
     2701 atccactaca agctattgca agtaaggcta tttacccgat taccccaatc ggaaatttgt
     2761 cagaaaatag ctatgctatt attttggttg aagttcagaa aataaaagtg attcgtacca
     2821 aaaagggtga aaatatggcc ttcttacagg cagatgatag taagaaaaaa ttggatgtca
     2881 ctctcttttc agacttatat cgtcaggttg gacaggaaat aaaagaggga gccttctact
     2941 atgtaaaagg aaaaatacaa tcacgtgatg gccgtctgca aatgattgca caagaaataa
     3001 gagaagcagt tgctgaacgc ttttggatac aggtgaaaaa tcatgaatcg gatcaagaaa
     3061 tttcacgcat tttagaacaa tttaaaggcc caatcccagt catcatccgg tatgaagagg
     3121 aacagaaaac catcgtttct ccccatcatt ttgtagctaa atccaatgaa ttagaggaga
     3181 aattgaatga aatcgttatg aaaacgattt atcgctaaaa atacggaaaa tagaagaatt
     3241 ttaaaatcaa atgtgatata atcaagaaga atgttaaaag aaaaaggagc ataaaccaat
     3301 atgaaacgta ttgctgtttt gactagtggc ggagacgcac ctggtatgaa cgctgccatc
     3361 cgtgcagttg ttcgtcaagc aatttcagaa ggaatggaag tgtttggtat ctatgacgga
     3421 tatgctggta tggttgccgg tgaaattcat cccctagatg cagcttcagt aggggacatc
     3481 atttctcgtg gtggtacttt tcttcactca gctcgttatc cagagttcgc tcaacttgaa
     3541 gggcaactta aagggattga gcaattgaaa aaacacggaa ttgaaggtgt agttgttatc
     3601 ggtggtgacg gatcttacca cggcgctatg cgtttgactg aacatggctt cccagctatt
     3661 ggtcttccag gtacaatcga taacgatatc gttggtactg actttacaat cggttttgac
     3721 acagcggtta ctactgccat ggacgctatc gataagattc gtgatacatc atcaagtcac
     3781 cgtcgtactt ttgtaatcga agttatggga cgtaacgctg gtgatatcgc tctttgggct
     3841 ggtattgcaa ctggtgctga tgaaatcatc atccctgaag caggcttcaa gatggaagat
     3901 atcgtagcaa gcatcaaagc tggttatgaa tgtggtaaaa aacacaatat catcgtctta
     3961 gctgaaggtg tgatgtcagc ggctgaattt ggtcaaaaac ttaaagaagc tggagataca
     4021 agcgaccttc gtgtaacaga acttggacat attcaacgtg gtggttctcc aactgcgcgt
     4081 gaccgtgttt tggcgtcacg tatgggtgca catgctgtta aacttcttaa agaaggtatc
     4141 ggtggtgttg cggttggtat tcgtaacgaa aaaatggttg aaaatccaat tcttggtact
     4201 gcagaagaag gggcattgtt tagccttact gcagaaggta agattgtggt taacaacccg
     4261 cacaaagccg atattgagct atctagcttg aataagagct tgtcataatt tacaatttag
     4321 ttaataagac caaaaaggtc atatatataa aggagtcaca aaaatcatga acaaacgtgt
     4381 aaagatcgtt gcaactttgg gtcctgcggt agaaatccgt ggtggtaaaa aattcggtga
     4441 ggacggatac tggggtgaaa aacttgatgt tgaagcttca gctaaaaaca ttgctaaatt
     4501 gattgaagct ggtgctaaca cattccgatt caacttctca cacggcgacc accaagaaca
     4561 aggtgagcgt atggcaactg ttaaacttgc ggaaaaaatt gcaggtaaaa aagttggttt
     4621 ccttcttgat acaaaaggac ctgaaatccg tacagaattg ttcgaaggtg aagctaaaga
     4681 atattcatac aaaactggtg aaaaaattcg tgttgcaact aaacaaggaa tcaaatcaac
     4741 tcgtgaagtg attgcgttga acgttgctgg tgctcttgat atctatgatg atgttgaagt
     4801 tggtcgtcaa gttttggttg acgatggtaa acttggtctt cgtgtggttg ctaaagatga
     4861 tgcaactcgt gaatttgaag ttgaagttga aaacgatggt atcatcgcta aacaaaaagg
     4921 tgtgaacatc cctaacacta aaattccttt cccagctctt gctgaacgcg ataacgacga
     4981 tatccgtttc ggtcttgaac aaggtatcaa cttcatcgca atttcattcg tacgtactgc
     5041 aaaagatgtg aacgaagttc gtgcaatctg tgaagaaact ggaaacggac atgttcaatt
     5101 gttcgctaaa atcgaaaacc aacaaggtat cgataactta gatgaaatca tcgaagcagc
     5161 tgatggtatt atgattgctc gtggtgatat gggtatcgaa gtaccgttcg aaatggttcc
     5221 agtttatcaa aaaatgatta tcaagaaagt caatgctgca ggtaaagttg ttatcactgc
     5281 aacaaacatg cttgaaacaa tgactgaaaa accacgtgca actcgttcag aagtatcaga
     5341 cgtattcaac gctgttatcg acggaactga cgctacaatg ttgtcaggcg agtctgcaaa
     5401 cggtaaatac ccactcgagt cagtaactac aatggctaca atcgacaaga acgctcaagc
     5461 tcttcttaat gaatacggac gtcttgattc agattcattt gagcgtaact ctaagacaga
     5521 agtaatggct tctgctgtta aagatgctac tagctcaatg gatatcaaat tggttgtaac
     5581 tcttactaag acaggtcata ctgcacgttt gatttctaaa taccgtccaa atgctgacat
     5641 cttagcattg acatttgacg aattgacaga acgtggcttg atgttgaact ggggtgttat
     5701 cccaatgttg acagatgctc catcttcaac tgacgatatg ttcgaaatcg ctgaacgtaa
     5761 agcggtagaa gcaggtctcg ttgagtcagg cgatgatatc gttatcgttg ctggtgtgcc
     5821 agtaggagaa gctgttcgca caaacacaat gcgtatccgc acagtacgtt aagaaaaata
     5881 taaaaaccta tcatatccag ctttctagcc tgtatgatgg gctctttttt tgtccagggg
     5941 gcaaaaaggg ggcaaaactt tcataatgga ttgatactct tcgaaaatca aattcaaacc
     6001 acgtcagcgt cgccttaccg tatatatgtt actgacttcg tcagttctat ctacaacctc
     6061 aaagcagtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
     6121 gtatgaaata agatatgcat aaattgatta gaaagtcaaa tgaatttcta caaatgtttt
     6181 agcaatcgca atctacttgt ctagattcga tctgatatat tttcgattta atgatatggt
     6241 atttaaaacc tccaaagtag cttgctccat tcttttacct acgtgagtct agatgttatt
     6301 tactgtttta gcgtttttgt gttctactct aaccattata gcattcttct cagctagtgt
     6361 actaaggagt gtgtgcctga aaatatggga actaaggggc tggtttatcg gtttctctag
     6421 tttagtattt gccttttgca aagtgatctt aaatgccttt ctctaaattt acatatcact
     6481 attgtttaac aaaatctaat ctattttagg tcacttattc tttttttgaa atgtagaatg
     6541 aactttttca aagtttttcg aatcttttaa aatctgtttg ttttatatcg ccattctccc
     6601 ccttttttaa ttctccctat atagcctgac aacttttccg atggtacgaa tatggttgct
     6661 ttcgtctagg tggatgtcgg agtattcggg attgagtttt tttgaggtag ccttggcgga
     6721 gtttcttgac atagttagtg ccgtctactt ggaagatgcc gatggtatta tagtcaatct
     6781 gtggggtatt cttgataaat aggtagtcgc tgtttcttat ctttggctcc atggacttgc
     6841 tgacgacata agcgattggg tcgtagtcgt ctgggataat ggaaactcca taactaaatc
     6901 gtcgtcctgc atcaagcggc tacctgcaga gataaactac ctaacacgag agtaagtagt
     6961 ctgtctgtag tcgtccagtc tgatgatttt tacgatactt cgtttttctg atcatacagt
     7021 tgcctctcgg cataggtcag aactttacct tgtctgggtg gtgcccgttg gtcgtagata
     7081 gattggatat cgctaggaga atccttttga actggaggaa agagggcatc aatcaagcta
     7141 ctgaatactt taactaagtc aaatatagta tttttcttag tagacctaac ccttttttca
     7201 taatttctaa tggtgttttt acttatacct atcttagtac ccaattctta ttgagtccaa
     7261 ccattactag tctatattgt tttatagttg attgagtttg gaatagtacg ctgtagctgc
     7321 taaaacattt ctaggaatta atttgccttt cctaatagag ttgttcatat cttatttcaa
     7381 tctactatat ttttcacctc taacaatcgc aatctcttct ttatccatga acgaaaacgc
     7441 tttctatctt tgtaagtaaa gcatcacacg aaatccacga aaatgaaaac ctttgttgtg
     7501 ttttcgtaaa aaatttgttg acagagcacg aaacgcctac tataattaaa tcaagtttaa
     7561 ggaaataaca aaaaaacaaa tcggagggaa agacgatgaa cacattaaat gagaaagtaa
     7621 tcaatatctg taaagcagta gttaaagaaa ctttaatcca agacatttag gagaaagaaa
     7681 tgaagaaatc aagaaaatta gccacattag gaatctgttc agccttgttt ttaggcttgg
     7741 ctgcttgtca acaacaacat gctacttctg aggggacgaa tcaaaggcaa agcagttcag
     7801 cgaaagttcc atggaaagct tcatacacca acctaaacaa ccaggtaagt acagaagagg
     7861 tcaaatctct cttatcagct cacttggatc caaatagtgt tgatgcattt tttaatctcg
     7921 ttaatgacta taataccatt gtcggctcaa ctggcttatc aggagatttc acttccttta
     7981 ctcacaccga atacgatgtt gagaaaatca gtcatctctg gaatcaaaag aagggcgatt
     8041 tcgttgggac caactgccgt atcaatagtt attgtctttt gaaaaattca gtcaccattc
     8101 caaagcttga aaagaatgac cagttgcttt tcctagataa tgatgcgatt gataaaggaa
     8161 aggtctttga ttcacaagat aaggaagagt ttgatattct attttcgaga gttccaactg
     8221 aggcaactac agatgtcaag gttcacgctg aaaagatgga aacattcttc tcacaatttc
     8281 aattcaatga aaaagctcga atgctgtctg tagtcttgca cgacaatctg gatggcgagt
     8341 atctgtttgt aggccacgtt ggggtcttag tacctgctga tgacggtttc ttatttgtag
     8401 agaaattgac tttcgaagag ccctaccaag cgattaaatt tgctagtaag gaagattgct
     8461 acaagtattt aggcaccaag tatgcggatt atacaggcga gggactggct aagcctttta
     8521 tcatggataa tgataagtgg gttaaacttt aatagtgtta tgatatgaca gtaatcttag
     8581 gatttttatt tctatttttg atgagttggt gggttatttc aatcgttaat agccagaaac
     8641 cacgcaaaaa tgaaacattt attggctata tccaaagata cgatattgat gggaatggct
     8701 atcaatcatt accgtgtcct cagaactgag aggagttctt gaaatcgtaa aactactttg
     8761 aacaagagtt acttcaaccc attggctccg acggattaag ttgctttcgt gaacaccaaa
     8821 atcagccgca atttcttcat aagtgcggta ttctcgcaca tattgaagag tggccataag
     8881 aaggtcttct aggcttaatt taggttttcg tccccctttt gtgtgtttaa gttgataagc
     8941 agtttttaat acagctaaca tctcttcaaa agtggtgcgc tgaacaccaa caagacattt
     9001 aaatcgtgca tcagttagtt gcttacttgc ttcataattc atagaactac tataccatat
     9061 tttgtttcgc aggaagtcta atgctaaaat cttatcagtg agaagatttc ttaaagttta
     9121 ttctttgtag tttcatctgt attagtacat aatttaactt agagaaaata ggaggattaa
     9181 tcgaatggaa ttaaaagatt ttacagaaaa agaacaggaa atgattaaga aaaggcttac
     9241 aatgtctaat attagtgaca aagaaactac tgagaagatt ctggcgctag taccacaaga
     9301 cttgattaag cgaatcccgt tttttgtcag aaaacatgct acaacacgta cgattaaacg
     9361 catttcaatt gaacaccctg aactctacgc tgtagctcaa acaagtggtg agattccaga
     9421 aaaaaaaacg cgaagaattg cgtcagatta tcacaactat ctttgaacaa aagatgaata
     9481 agcatagtat taagtagaga atgaaaaaat attttattgg cggtttggga agcaatgcct
     9541 atcatagcaa ggattttctt taagaactag attcgcaggt ctattttcta aatccatatg
     9601 aaaagcatct tcgagatgaa acagaattga aatcatggtt taaaaatgag attgtagagg
     9661 aagaatctat ctgtctgata ggtcattcta ttggaggcga tttagctcgt tatttcgcat
     9721 cggaatttga agaagtaaag a
//
LOCUS       DAVLAQ010000069         9498 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000069 DAVLAQ010000000
VERSION     DAVLAQ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.069"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            123..5033
                     /locus_tag="VXB71_001788"
     CDS             123..5033
                     /locus_tag="VXB71_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0451860.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYRFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            5123..6319
                     /locus_tag="VXB71_001789"
     CDS             5123..6319
                     /locus_tag="VXB71_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0451861.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     VALTEK"
     gene            6455..6982
                     /locus_tag="VXB71_001790"
     CDS             6455..6982
                     /locus_tag="VXB71_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0451862.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            7059..7415
                     /gene="glnR"
                     /locus_tag="VXB71_001791"
     CDS             7059..7415
                     /gene="glnR"
                     /locus_tag="VXB71_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0451863.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            7452..8798
                     /gene="glnA"
                     /locus_tag="VXB71_001792"
     CDS             7452..8798
                     /gene="glnA"
                     /locus_tag="VXB71_001792"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0451864.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(8894..9013)
                     /locus_tag="VXB71_001793"
     CDS             complement(8894..9013)
                     /locus_tag="VXB71_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0451865.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3052 a         1732 c         2081 g         2633 t
ORIGIN      
        1 tttttgtcta aaaatgtttt aggataaaaa tgtgattatc atggttctag agtttgataa
       61 aaaactacag aatataaagc gctttcttta aaacaacaaa atcaatcttt taggaggaga
      121 aaatgaagaa tccatttttt gaaagacgtt gtcgttacag tattcgtaag ttatcagtag
      181 gagcctgctc gctgatgatt ggtgctgttt tatttgctgg tccagccttg gctgaagaaa
      241 ctgcagttcc tgaaaatagc ggagctaata cagagcttgt ttcaggagag agtgagcatt
      301 cgaccaatga agctgataag cagaatgaag gggaacatgc tagagaaaac aagctagaaa
      361 aggcagaagc agctagcgca gctaaaccag aggaaaaagc aggtgaggtg gttgcagaaa
      421 caccatctgc agaagcaaaa cctaagtctg acaaggaaac agaagcaaag cccgaagcaa
      481 ctaaccaagg ggatgagtct aagccagcag cagaagctaa taagactgaa aaagaagtcc
      541 agccagatgt ccctaaaaat acagaaaaaa cattaaaacc aaaggaaatc aaatttaatt
      601 cttgggaaga attgttaaaa tgggaaccag gtgctcgtga agatgatgct attaaccgcg
      661 gatctgttgt cctcgcttca cgtcggacag gtcatttagt caatgaaaaa gctagcaagg
      721 aagcaaaagt tcaagcctta tcaaacacca attctaaagc aaaagaccat gcttctgttg
      781 gtggagaaga gttcaaggcc tatgcttttg actattggca atatctagat tcaatggtct
      841 tctgggaagg tctcgtacca actcctgacg ttattgatgc aggtcaccgt aacggggttc
      901 ctgtatacgg tacactcttc ttcaactggt ctaatagtat tgcagatcaa gaaagatttg
      961 ctgaagcttt gaagcaagac gcagatggta gcttcccaat tgcccgtaaa ttggtagaca
     1021 tggccaagta ttatggctat gatggctatt tcatcaacca agaaacaact ggagatttgg
     1081 ttaaacctct tggagaaaag atgcgccagt ttatgctcta tagcaaggaa tatgctgcta
     1141 aggtaaacca tccaatcaag tattcttggt atgatgccat gacctataac tatggacgtt
     1201 accatcaaga tggtttggga gaatacaact accaattcat gcaaccagaa ggagataagg
     1261 ttccggcaga taacttcttt gctaacttta actgggataa ggctaaaaat gattacacta
     1321 ttgcaactgc caactggatt ggtcgtaatc cttatgatgt atttgcaggt ttggaattgc
     1381 aacagggtgg ttcctacaag acaaaggtta agtggaatga cattttagac gaaaatggga
     1441 aattgcgcct ttctcttggt ttatttgccc cagataccat tacaagttta ggaaaaactg
     1501 gtgaagatta tcataaaaat gaagatatct tctttacagg ttatcaagga gaccctactg
     1561 gtcaaaaacc aggtgacaaa gattggtatg gtattgctaa cctagttgcg gaccgtacgc
     1621 cagcggtagg taatactttt actacttctt ttaatacagg tcatggtaaa aaatggttcg
     1681 tagatggtaa ggtttctaag gattctgagt ggaattatcg ttcagtatca ggtgttcttc
     1741 caacatggcg ctggtggcag acttcaacag gggaaaaact tcgtgcagaa tatgatttta
     1801 cagatgccta taatggcgga aattccctta aattctctgg tgatgtagcc ggtaagacag
     1861 atcaggatgt gagactttat tctactaagt tagaagtaac tgagaagacc aaacttcgtg
     1921 ttgcccacaa gggaggaaaa ggttctaaag tttatatggc attctctaca actccagact
     1981 acaaattcga tgatgcagat gcatggaaag agctaaccct ttctgacaac tggacaaatg
     2041 aagaatttga tctcagctca ctagcaggta aaaccatcta tgcagtcaaa ctatttttcg
     2101 agcatgaagg tgctgtaaaa gattatcggt tcaacctagg acaattaact atctcggaca
     2161 atcaccaaga gccacaatcg ccgacaagct tttctgtagt gaaacaatct cttaaaaatg
     2221 cccaagaagc ggaagcagtt gtgcaattta aaggcaacaa ggatgcagat ttctatgaag
     2281 tttatgaaaa agatggagac agctggaaat tactaactgg ctcatcttct acaactattt
     2341 atctaccaaa agttagccgc tcagcaagtg ctcagggtac aactcaagaa ctgaaggttg
     2401 tagcagtcgg taaaaatgga gttcgttcag aagctgcaac cacaaccttt gagtggggga
     2461 tgactgtcca agacacaagt cttccaagac ctctagcaga aaacatcgtt ccaggggcta
     2521 ctgttatcgg aagtaccttc ccagatacag aaggtggaga aggtattgaa ggtatgttga
     2581 acggtaccat tactagcttg tcagataaat ggtcttcagc tcagttgagt ggtagtgtgg
     2641 atattcgttt gaccaagcca cgtaccgttg ttagatgggt catggatcat gcaggggctg
     2701 gtggtgagtc tgttaacgat ggcttgatga acaccaaaga ctttgacctt tattataaag
     2761 atgcagatgg tgagtggaag ctagctaagg aagtccgtgg caacaaagca cacgtgacag
     2821 atatcactct tgataaacca atcactgctc aagactggcg cttgaatgtt gtcacttctg
     2881 acaatggaac tccatggaag gctattcgta tctataactg gaaaatgtat gaaaagcttg
     2941 atactgagag tgtcaatatt ccgatggcca aggctgcagc ccgttctcta ggcaataaca
     3001 aggtacaagt tggctttgca gatgtaccgg ctggagcaac tattaccgtt tatgataatc
     3061 caaattctca aactccactc gcaaccttga agagcgaagt tggaggagac ctagcaagtg
     3121 caccattgga tttgacaaat caatctggtc ttctttatta tcgtacccag ttgccaggca
     3181 aggaaattag taatgtccta gcagtttccg ttccaaaaga tgacagaaga atcaagtcag
     3241 tcagcctaga aacaggacct aagaaaacaa gctacgccga aggggaggat ttggacctta
     3301 gaggtggtgt tcttcgagtt cagtatgaag gaggaactga ggacgaactc attcgcctaa
     3361 ctcacgcagg tgtatcagta tcaggttttg atacgcatca taagggagaa cagaatctta
     3421 ctctccaata tttgggacaa ccagtaaatg ctaatttgtc agtgactgtc actggccaag
     3481 acgaagcaag tccgaaaact attttgggaa ttgaagtaag tcaggaaccg aaaaaagatt
     3541 acctagttgg tgatagctta gacttgtctg aaggacgctt tgcagtggct tatagcaatg
     3601 acaccatgga agaacattcc tttactgatg agggagttga aatttctggt tacgatgctc
     3661 aaaagactgg tcgtcaaacc ttgacgcttc gttaccaagg tcatgaagtc aactttgatg
     3721 ttttggtatc tccaaaagca gcattgaacg atgagtacct caaacaaaaa ttagcagaag
     3781 ttgaagctgc taagaacaag gtggtctata actttgcttc accagaagta aaagaagctt
     3841 tcttgaaagc aattgaagcg gccgaacaag tgttgaaaga ccatgaaact agcacccaag
     3901 atcaagtcaa tgaccgactt aataaattga cagaagctca taaagctctg aatggtcaag
     3961 agaaatttaa ggaagaaaag acagagcttg atcgtttaac aggtgaggtt caagaactct
     4021 tggctgccaa accaaaccat ccttcaggtt ctgccctagc tccgcttctt gagaaaaaca
     4081 aggccttggt tgaaaaagta gatttgagtc cagaagagct tgcaacagcg aaacagagtc
     4141 taaaagatct ggttgcttta ttgaaagaag acaagccagc agtcttttct gatagtaaaa
     4201 caggtgttga agtacacttc tcaaataaag agaagactgt catcaagggt ttgaaagtag
     4261 agcgtgttca agcaagtgct gaagagaaga aatactttgc tggagaagat gctcatgtct
     4321 ttgaaataga aggtttggat gaaaaaggtc aagatgttga tctctcttat gcttctattg
     4381 tgaaaatccc aattgaaaaa gataagaaag ttaagaaagt atttttctta cctgaaggca
     4441 aagaggcagt agaattggct tttgaacaaa cggatagtca tgttatcttt acagcacctc
     4501 actttactca ttatgccttt gtttatgaat ctgctgaaaa accacaacct gctaaaccag
     4561 caccacaaaa cacagtcctt ccaaaaccta cttatcaacc ggcttctgat caacaaaagg
     4621 ctcctaaatt ggaagttcaa gaggaaaagg ttgcctttca tcgtcaagag catgaaaatg
     4681 ctgagatgct agttggggaa caacgagtca tcatacaggg acgagatgga ctgttaagac
     4741 atgtctttga agttgatgaa aacggtcagc gtcgtcttcg ttcaacagaa gtcatccaag
     4801 aagcgattcc agaaattgtt gaaattggaa caaaagtaaa aacagtacca gcagtagtag
     4861 ctacacagga aaaaccagct caaaatacag cagttaaatc agaagaagca agcaaacaat
     4921 tgccaaatac aggaacagct gatgctaatg aagccctaat agcaggctta gccagccttg
     4981 gtcttgctag tttagccttg accttgagac ggaaaagaga agataaagat taaatatcga
     5041 aaaatcttgt gaaatctttc cttatatttc taaagtgtga tataatagtt tcgaataaaa
     5101 taaataaagg agtttttgta acatggcaaa acttactgtt aaagacgttg acttgaaagg
     5161 taaaaaagtc ctcgttcgtg ttgacttcaa cgtaccattg aaagatggtg taatcactaa
     5221 cgataaccgt atcacagcag ctcttccaac tattaagtac atcatcgaac aaggtggacg
     5281 tgcaattctt ttctctcacc ttggacgtgt gaaagaagaa gctgataaag ctggtaaatc
     5341 acttgctcct gtagcagctg acttggcagc aaaacttggt caagatgttg ttttcccagg
     5401 tgtcactcgt ggtgctgaat tggaagcggc aatcaacgct cttgaagatg gacaagttct
     5461 cttggttgaa aacactcgtt acgaagatgt tgacggcaag aaagaatcta aaaacgatcc
     5521 tgaacttggt aaatactggg catcacttgg agatggtatc ttcgtaaacg atgcattcgg
     5581 tacagctcac cgtgcacacg catctaacgt tggtatctca gcaaacgttg aaaaagcagt
     5641 tgctggtttc cttcttgaaa acgaaattgc ctacatccaa gaagcagttg aaactccaga
     5701 acgtccattc gtggctatcc ttggtggttc aaaagtttca gacaagatcg gtgttatcga
     5761 aaacttgctt gaaaaagctg ataaagtcct tatcggtggt gggatgactt acacattcta
     5821 caaagcacaa ggtatcgaaa tcggtaactc acttgtagaa gaagacaaat tggatgttgc
     5881 gaaagctctt cttgaaaaag caaatggtaa attgatcttg ccagttgact caaaagaagc
     5941 taacgcattt gctggttaca ctgaagtgcg tgacactgaa ggtgaagcag tttctgaagg
     6001 cttccttggt cttgacatcg gtccaaaatc tatcgccaaa tttgacgaag ctttgactgg
     6061 tgccaaaaca gttgtatgga acggacctat gggtgtattt gaaaacccag atttccaagc
     6121 tggtacaatc ggtgtgatgg acgctatcgt gaaacaacca ggagttaaat caatcatcgg
     6181 tggtggtgac tcagctgccg cagcgattaa ccttggccgt gcagacaagt tctcatggat
     6241 tagtacgggt ggtggagcat caatggaact tcttgaaggt aaggttcttc caggacttgt
     6301 agccttgaca gaaaaataag attttataaa caaatcaaag aagagaggga tgaaagttcc
     6361 tcttttcttt tgcttaaaat aaaaacgctt cctctcaact attactcata aaaatcaccg
     6421 atttatgata aaatggaaat agaaagttga gattatgagt tattttaaaa aatataaatt
     6481 cgataaatcc cagttcaaac ttggtatgcg aacctttaaa acaggtattg ctgtttttct
     6541 agttctcttg atttttggct tttttggctg gaaaggtctt caaattggtg ctttgacagc
     6601 cgtttttagc ctgagggaga gttttgatga gagtgttcat tttgggactt cgcgtattct
     6661 aggaaatagt atcggtggac tctatgcctt ggtcttcttc ttattaaata cctttttcca
     6721 cgaagccttt tgggtgacct tggtagttgt tccaatctgc accatgttaa ccattatgac
     6781 aaatgtagcc atgaataaca aagcaggggt tattggtggt gtagcagcta tgttaattat
     6841 taccctatca attccaagtg gtgagacaat tttgtacgtg tttgtgcgtg tattagaaac
     6901 atttatggga gtttttgtcg caattatcgt aaattacgat attgatcgta ttcgtctctt
     6961 tttagagaaa aaagaaaaat aatgttacat tttataacat tattaattga cgtttgtctt
     7021 tttttagact ataatagaca gaaagaagga aattgtaaat gaaggaaaaa gaatttcgcc
     7081 gaaatatggc tgtttttcct atcggcagtg ttatgaagtt gaccgatcta tcggcgcgtc
     7141 agattcgtta ttatgaaaat caagagttga tcaagcccga tcgaaacgaa ggaaatcgtc
     7201 gcatgtattc cttgaatgac atggatcgtc tgcttgaaat caaagattat atctctgaag
     7261 gttataatat cgctgccatt aagaaaaaat atgctgaacg tgaagcgaaa tccaagaaag
     7321 cggttagtca gactgaagta cgtcgtgcac ttcacaatga actcctccaa caggggcgtt
     7381 ttgcttcagt acagtcacct tttggtcgcg gttaggcaac cgcaagtagt catagattaa
     7441 ggagaaaact tatgccaatc acagctgcag atattcgtcg tgaagtcaag gaaaaaaatg
     7501 ttacctttat tcgtcttatg ttctcagata ttttgggaac catgaaaaac gtcgaaattc
     7561 ctgctacaga tgaacagtta gataaggtct tgtcgaacaa ggttatgttt gatggatctt
     7621 ctattgaagg ttttgtacgt atcaatgagt cggatatgta cttgtacccg gacttggata
     7681 catggacagt cttcccttgg ggagatgaaa atggaagtgt tgcaggtctg atctgtgatg
     7741 tttatacaac agaaggtgaa ccatttgcgg gtgaccctcg tggtaatttg aaacgagctc
     7801 ttcgtcacat ggaagaagtt ggattcaaat ccttcaacct tggtccagag ccagaattct
     7861 tcctatttaa gttggatgaa aatggggacc caacacttga agtgaatgac aagggtggct
     7921 actttgattt ggcacctact gaccttgcgg acaacacacg tcgtgagatt gtgaatgtct
     7981 tgaccaaaat gggatttgaa gtagaagcga gtcaccacga ggttgcggtt ggacagcatg
     8041 agattgactt taagtacgat gaagttctcc gtgcttgtga taagattcaa atctttaaac
     8101 ttgttgttaa aaccattgct cgcaaacacg gactttacgc aacatttatg gcgaagccaa
     8161 aatttggtat tgctggctca ggtatgcact gtaatatgtc cttgtttgat gcagaaggaa
     8221 ataacgcctt ctttgatcca aatgatccaa aaggaatgca gttgtcagaa acagcttacc
     8281 atttcctagg cggtttgatc aagcatgctt acaactatac tgccatcatg aacccaacag
     8341 ttaactcata caaacgtttg gttccaggtt atgaagcgcc tgtttacatt gcttgggctg
     8401 gtcgtaaccg ttcgccactt gtgcgcgtac ctgcttcacg tggtatggga actcgtcttg
     8461 agttgcgttc agtggatcca atggcgaacc cttacgttgc tatggctgtt cttttggaag
     8521 ttggtttgta tggtattgaa aataaaatcg aagcaccagc tcctatcgaa gaaaatatct
     8581 acatcatgac agcagaagag cgcaaggaag ctggtattac agaccttcca tcaactcttc
     8641 acaacgcttt gaaagctttg acagaagatg aagtggttaa agctgctctc ggagatcaca
     8701 tctatactag cttccttgaa gccaaacgaa tcgaatgggc aagttatgca accttcgttt
     8761 cacaatggga aattgataat tatttagacc tttactaata ctaatataga agaaagattg
     8821 cctgtgggta aacagtcaca cagcagtcta agccatcaaa tacctataac ccttaaaata
     8881 gcgatttcgg tcgctattta tttttcgaaa aatcctcttg actcttttgc gaattagatt
     8941 tatcatcaga cgtgtagaag aaaattaagg agtcactatg gaaaaattca atttcaaaaa
     9001 caatatcggg caagaaaaca agttacttca aatcgaaatc tacaagttta ctaacttttg
     9061 caagcttcaa aattacacat ctgtaaatat tttttcgaaa gatatatttg aagccatagt
     9121 aaattgagac tagaatagta cactacatct gctaaaaatt tctagaaact aatttaactt
     9181 tcctaatcga tttgtttaca tcttatttca atctactata ttatctcaat aaatgatgat
     9241 ggcgactgtt ttgtttgtgc ttgtcgattt ttgaatcctg atcgagcgga agaatatttc
     9301 tgccgaggtt gccaagggga aaatcctgaa gatattgaat tttatgatga acaattacag
     9361 gcagaaaagg tggaggtttt gaatattcga ttggaagtaa aaaattgaat tatctacaat
     9421 ctcatcaaca ataaacctat ttcaacccca ttatctatag gcgtattttt acgccttttt
     9481 atatacttga agcacata
//
LOCUS       DAVLAQ010000070         9466 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000070 DAVLAQ010000000
VERSION     DAVLAQ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.070"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..297)
                     /locus_tag="VXB71_001794"
     CDS             complement(<1..297)
                     /locus_tag="VXB71_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0451866.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIG"
     gene            complement(299..2122)
                     /gene="dnaK"
                     /locus_tag="VXB71_001795"
     CDS             complement(299..2122)
                     /gene="dnaK"
                     /locus_tag="VXB71_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0451867.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(2602..3126)
                     /gene="grpE"
                     /locus_tag="VXB71_001796"
     CDS             complement(2602..3126)
                     /gene="grpE"
                     /locus_tag="VXB71_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0451868.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(3153..4187)
                     /gene="hrcA"
                     /locus_tag="VXB71_001797"
     CDS             complement(3153..4187)
                     /gene="hrcA"
                     /locus_tag="VXB71_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0451869.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(4351..4860)
                     /locus_tag="VXB71_001798"
     CDS             complement(4351..4860)
                     /locus_tag="VXB71_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0451870.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            5468..7801
                     /locus_tag="VXB71_001799"
     CDS             5468..7801
                     /locus_tag="VXB71_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0451871.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            7814..9277
                     /locus_tag="VXB71_001800"
     CDS             7814..9277
                     /locus_tag="VXB71_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0451872.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWKLEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            9277..>9466
                     /locus_tag="VXB71_001801"
     CDS             9277..>9466
                     /locus_tag="VXB71_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV0451873.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         2936 a         1782 c         1842 g         2906 t
ORIGIN      
        1 accaattatg aacggtatta caaatttata tgtttgtatt tctaatgata tcatagctgg
       61 taccatcgcc gatacaaatg cagacaacaa tactgaggta acaaaattcc ttaccgcttc
      121 atcatttttg atacaactat catgttcagc taatataatt tctctatatc tagctaaata
      181 ttctattgga atattatcaa taaaatcttt tgatgttcta tagttatcag cttgattaca
      241 aaaatcatta taaacttttc gtgtattttt tagatactct tcatccaata cactcatctt
      301 acttttccgt aaactctccg tctacgacgt catcgcctgc gttccctgtt gcttgtgcgc
      361 cttctgctcc ttcttgagct tgttgcgctg ctgcggcttg ttcgtagagt ttaacagcaa
      421 gtccttgagc tttttcgttc aatgcttcaa gttttgtttt catgtcgtcc aagttgttgt
      481 cttcttgagc tttcttaagg tcatcaaggg cagcttgggc agcgtcacgt tctgcgtcga
      541 agcctttacc ttcagtttcc ttgattgtct tttcagtcgc aaagattgct tggtctactt
      601 cattacgaag gtctacttct tctttacgtt tcttatcggc ttcagcgttt gcttctgcat
      661 ctttcatcat gcggtcgatt tcttcgtcag tcaaacctga gttcgattgg atgacaatag
      721 tttgttcttt ttgagttcca aggtctttgg ccttaacaga cacgataccg ttcttgtcga
      781 tgtcaaatgt tacttcgatt tgaggaattc cacgaggtgc agctgggata tcagtcaatt
      841 ggaagcgtcc aagagtcttg ttatctgctg ccattgggcg ttcaccttga agaacgtgga
      901 tatcaacggc tggttggttg tctgctgctg ttgagaagac ttgtgattta gatgttggga
      961 ttgtagtgtt gcgatcgata agttttgtaa atactccacc cattgtttcg ataccaagtg
     1021 acaatggcgt tacatcaaga aggacaacgt ccttgacatc accagtaatc acaccacctt
     1081 ggatagccgc acccatagca actacttcat cagggtttac tgatttgttt ggttctttac
     1141 cagtttcagc tttaacagct tcaacaacgg cagggatacg agttgaacca ccaacaagga
     1201 taacttcgtc gatttctgac aagctcaaac ctgcatctga aagggcttga cgaactggaa
     1261 cttttgtacg ttcaacaagg tcacgagtca aatcgtcaaa tttcgcacga gtcaaagtca
     1321 tttccaagtg aagaggtcca gcctcacctg cagtgataaa tggcaagctg atttgtgttg
     1381 aagttacacc agaaaggtct ttcttcgctt tttcagccgc atctttcaaa cgttgcattg
     1441 ccatcttgtc agtagacaag tcgataccgt tttctttctt gaattctgct accaagtggt
     1501 caatgatttt ttggtcaaag tcgtcaccac caagtttgtt gtcccctgca gttgacaata
     1561 cgtcgaagac accgtcaccc aattcaagga tagagacgtc gaatgtacca ccaccaaggt
     1621 caaataccaa gattttttct tctttgtcag tcttgtccaa accataagca agagctgctg
     1681 cagttggttc gttaacaata cgttctactt caagaccagc aattttacca gcgtcttttg
     1741 ttgcttgacg ttgagcgtcg ttgaagtaag ccggaactgt gataacagct ttggttactt
     1801 tctcaccaag gtagtcttca gcgtagcctt tcaagtattg aaggatcata gctgagattt
     1861 cttgtggagt gtattctttt ccatttgcag aaactttttc agaagttccc atcttagatt
     1921 tgatagagat aactgtatct gggtttgtaa ctgcttgacg ttttgcagca tcaccaacga
     1981 tgatttctcc gtttttgaat gagactacag atggagttgt gcggtttcct tctgggtttg
     2041 cgatgatttt gctttcagtt ccttcaagaa ctgcaactgc tgagtttgtt gtacctaagt
     2101 caataccgat aattttagac atgtgttttt ctccttgtta gttaattttc tatttttctt
     2161 tttgatactc ttcttaagtg gcgacgccgt cagagcttga cttcgtcagt ctcttttact
     2221 aaactttgag cctaaggtct caaaatttgc gcaaatagcg ccacggcgaa gagtatcgtc
     2281 tttggttcgc ttcgctcact attacaaagc aaaacatatt ttatctttct tcatagttta
     2341 ttgtcgtttc ggacaagttt tctattatgt aaattgcgac acgaggagtc gaaatcgatt
     2401 ttatttcgac gacgagttag taaggaagct aggcaaacgc catagcaatt gccgttttct
     2461 gacgagttgc tttagctacc gtcagaattg ccgaatcgaa cacgccctaa gctctgagta
     2521 aaaaagatag attttcttgt gttcatcgaa cacttcgtca atctcctatt tttactgcga
     2581 gctttttacg ggctttgtat cttagttata caccactacc attgctgggc gtaggatgcg
     2641 gtcatggagt ttgtagcctt tttgaaagac ttgggcgatg gtatctactg ggtgttcatc
     2701 gtctgctggg agagtttgga tggccatatg gtagttatgg tcaaattcgc catctgctgc
     2761 gatttcttca attccttctt ctttcaaagc gtgaatcaag ctttcttgca ccatccccaa
     2821 gcccttcttc acatcatctg tcaaaccttc aactgcaagt gcacgctcaa ggttgtcaag
     2881 agatggtaag attgcttttg ccaagtcctg gctacgataa cgttgcaagt tttgacgttc
     2941 ttcattggca cggcgttgga tattttgcat ttctgcatga gcgcgaagat atttgttttc
     3001 gaactcatct gcacgttcat ttgccaagtc caactcagac ttttcaggag ttgtttcttc
     3061 agctgtttcc acaacttcct cttcttgaac ttcttctact tcttcatttt ttatatcttg
     3121 ggccatgttc gcctccttta atgatttcaa tcttaatgta cttcgtaatg attactgctg
     3181 aggtagcggt aaaaatctgt caacttcatg gtcaaaacac ggttgaccac attgatttga
     3241 ttgattagct gttggtaatc cagattaact ggaccgataa tggctagaat tccaactccc
     3301 cgataaggaa tgaggaactt actactaatc accgctaggt cagctaaaca ggactcttga
     3361 ccgtctgcaa cacgaacatt ttgcatctga tcctcacgca acccctcacg aatctccaag
     3421 gccacctttt gcggttggtc aaagaactga taggctgcta gattggcaaa attcaagaga
     3481 ttgaccttgc ccgccatcac aatgttttcg ttgaacattt ccttaaagat gtgttcaaag
     3541 agatcgatga cattatccgt tgttgtaaag taacgctgga taatctgcgg aatctccgtc
     3601 cgaatcttgt agtgaatatc taaaacggtg tgaccgagga aacgttcctg aatgatgctc
     3661 ttcagtttca gcaaatcctc ctgcaagaag ttccttggaa tcagaaactg actagtaacc
     3721 gttcgcgact cgtctagggt aaataccgcc aaggctgtat gttgccccaa aacaacgata
     3781 tcaaaggctg tcaaacgttg cctgctcggc tcaacatcca gtgccactac cgtacagcca
     3841 ctcaggtctg ttagcaagtt agcagcctct tgcagaatat cctccaattt gaagaattcc
     3901 tgatcaaagg ctttgacaat ctcatatacc tcattttcag ccagtcggtc aaaatccagt
     3961 gagtgtttca catagtactg aaaaccagca acacttggca tccgaccgct tgaagtatga
     4021 gccttctcaa gcaacccttg tttttctagt tccgccatgt cattacgaat ggttgcactg
     4081 ctagagttaa tagactcttg caaggctttt gatccgacag gttcgtgcgt tttggtaaag
     4141 atgtcaataa tcagatttaa aatatcctgc tgacgctctg taaccatctc atcactcctc
     4201 tctgtctgat caattagcac tcaatgcatc caagtgctaa cttatgattc tattatacac
     4261 ccttagaaga gaatgtcaag acaaaaactc aaaaaattag cactctttta taaagagtgc
     4321 taaaaatcaa tctgaagacc tagaaccttg ctattcatct actcggtatt tcctttttag
     4381 tctgaaataa ccatgaatta gataagaaat cagaaaagca tataaaacaa aaataagaaa
     4441 gaaagacata gaaagatcct ctctaaacaa actcatacaa acaacaagac cacctaagaa
     4501 agtagctata caggaacgaa gtctagatcg cataacttcc catttgagcc ccttactcat
     4561 atagacttga tcctctggaa gtaaatcaga agacgattta cgaagaatcg aacaagaacc
     4621 tgctcctatc aattcccaac ctctatctct aaaatcttgc agttcacgct tatgctcttt
     4681 aagaaatcta gaatcataga tacgatagat aacatcgtcc ggttgacctt gctcaaaata
     4741 gaacaaacca aaacgactag ttctatacct ccaacctttc aaatgcatct catgtaaata
     4801 ttcttctttc ttgtccaaat caacaatggt gaaaatccga aattctactc tgctattcat
     4861 tgtcttaccc caaaattaga aaacatgcct agcgttattt attagataat tctttccact
     4921 tttgactcaa tctccaaaaa atataagaaa tctgaatcgc aaaaactatc aataaaaccc
     4981 aatctattat gaaaatcaaa aacacttccc aactgaaaga actacctcca gtgacaaact
     5041 ttgagaaaaa cggtagtaga gctaaaaaga gaagcaaaat aggaagcatc cgcattgtta
     5101 aaatcctttt ggcataaaaa aatctttatt taaacgaaaa tattatggca aaatttacgc
     5161 cagtttttga acggctgatg tagatatttt atactttcaa aatgtttaaa tgtgattatt
     5221 tatttttgaa aaatagctca ccagcccgac tgaaagtgct tatagaatga taataagtcg
     5281 cctgccgaaa acagcgaaaa atagcagtgt tatgcggaga taatctgacg cgatgcgaaa
     5341 gtatattgca tacttatttt caacaattta gcagagtatt tttataagtg tgatataata
     5401 gaagtataat ttgttctgat agtttatttt atggagaagt agatttttag aatgcggagg
     5461 attcaatatg gttgagttta taaagtctaa gaaagaaatg agtgaggagg atattaaagc
     5521 aaatttcatc actcctgcta ttgtatccaa aggatggaaa aatggtgagc atatcgctta
     5581 cgaagaatac ttcactgatg gtcgaattga agttagagga gataaggctc gtcgtaaaga
     5641 aggaaaaaaa tcagactatt cactgtatta ccaatttgga actcgaattg caattgttga
     5701 ggcaaaggat aataaacaca gcgttcgagc aggattacaa caagctattg aatatggaga
     5761 gattttagat gttccatttg tttattcttc gaatggtgat ggctttattg aacacgaccg
     5821 tatcacgaga gaagaacgtg agctggagtt agacgaattc cctactcgtg aagaattatt
     5881 ttctcgtatg acgaaggaaa aaggattgac gtacgaaatt acagaagcta tctcaactcc
     5941 atactataca gacgccttct caatgaaaac gccacgctat tatcagcaaa tagctatcaa
     6001 ccgtactatt gaaacagttg ccagaggaca aaaacgagta atgtttgtga tggcaacagg
     6061 aacggggaaa acgttcatgg cttttcaaat tattcatcgc cttcgaaaag ctggtttggc
     6121 taaacgagtt ttattcttag cggatagaaa catcttagta gaccaaacga tggctgaaga
     6181 ctttaagcca ttcgaaaagg taatgacgaa aattacacca aaacttttga ctgctcctga
     6241 aaaattaaat tcttttgaaa tttatctagg gctttatcag caactaactg gtgaagatgg
     6301 aactgaaaca cattatcaaa aatttgataa agacttcttt gatttaatcg taattgatga
     6361 agcgcaccgt ggttcagcta aggaaaacag taactggcgt aagataattg attatttcag
     6421 ttctgcgaca cagattggga tgaccgctac tcctaaagaa accaagaatg cttccaatac
     6481 ggaatacttt ggtgagccaa tctatactta tagtttaaaa cagggaatcg aggatggttt
     6541 tttggctcca tatcgtgtta tgagggttaa tttagatgtg gatgtggatg gttatcgtcc
     6601 agaaactgga aaagttgata ctaacggaca attaatagaa gataggtact acggcaggaa
     6661 agattttgat aaaaccattg tcattgatga tagaacgcaa agagttgcca agtttgtttc
     6721 tgattatatg aagcaaaaca atgcacgatt tgataaaaca attgtttttt gtgttgatat
     6781 tgaccatgcc gagcgaatgc gtgctgcact tgtaaaagag aatctagact tagtccaaga
     6841 agactatcgt tatgtcatgc aagtaactgg tgacaacgct gaaggaaaag ctcaactgga
     6901 taactttatg gatgtcaatt ctaattttcc cgctatggta acaacgtcta aattattaac
     6961 gacaggagtt aatgctaaaa catgtcgttt gattgtttta gactctaata tccaatccat
     7021 gactgaattt aaacaaatta ttggtcgtgg cacacgtctt tatcctcaaa aggggaaaga
     7081 attttttacg attattgatt ttcgaaatgt taccaatttg tttgctgacc ctgattttga
     7141 tggtgagcca gtgaaggtgc tggaaacagg tgcgaaaaca gtcagtggtt ccacgcccgg
     7201 tttcgtagat gaggaaggtg acccagtaga aaaatatatc gttacagaca agcaggttac
     7261 cattcttaat tctactgttc aagtattgga tgaaaacggg aaactgatta ccgaaagcct
     7321 gaccgactac actcggaaga atatcttagg tagctacgcc actttgaacg attttatcac
     7381 agtttggcat acggcggata aaaagaagct tatcttagac gaactttata aaaaaggagt
     7441 ttatctagat gctattcgag agtcggaggg aatatcagaa caagaaatcg atgattttga
     7501 tttactccta aaacttgcct atggtcaaaa agaattaacc aaaacggaac gtatcaataa
     7561 gctcaaacaa agcggatatt tatataaata tagtgaggaa gcgcgtgctg ttttggaaat
     7621 tttactgaac aaatacatgg ataaaggtat tggagaactc gaaagcattg aaacattaaa
     7681 acttccagaa tttcagatat atggtggaac cttcaaaatc atcaatactt attttggaga
     7741 taaaaaacga tatttacaag caattaaaga attggagcaa gagctattta cagtagctta
     7801 atgaaaggaa agtatgtcaa ttacatcatt tgtaaaaaga attcaagata tcactcgaaa
     7861 cgatgctggt gttaatggtg atgctcaacg tattgagcaa atgtcttggt tattattctt
     7921 aaaaatttat gatagccgtg aaatggtttg gaaattagaa gaagacgagt atgagtcaat
     7981 tatcccagag gaattaaaat ggcgaaattg ggctcatgct caaaatgggg aacgggtatt
     8041 gacaggcgat gaattacttg attttgtcaa taacaagtta ttcaaagagt tgaaagagct
     8101 tgaaataact tcaattatgc ctattcgaaa aacgattgtt aaatcagctt ttgaagatgc
     8161 gaacaactat atgaaaaatg gcgtcttgtt acgccaagtc atcaatgtta ttgatgaagt
     8221 tgatttcaat agccctgaag atcgtcattc gtttaatgat atttacgaaa aaattcttaa
     8281 agatattcaa aatgctggga actcaggaga attttatacg ccacgtgcag cgactgattt
     8341 tattgccgaa gttcttaacc caaaacttgg agaatcaatg gcagaccttg cttgcggaac
     8401 aggaggcttc ttgacttcga ctctgaaccg tttaagtagt caacgtaaaa ctagtgaaga
     8461 taccaaaaaa tataatacag ctgtttttgg tattgaaaag aaagcatttc ctcatctttt
     8521 agcagttaca aatctgtttc ttcacgaaat tgatgaccct aaaattgttc atggaaatac
     8581 tttggagaaa aatgttcgtg aatatacgga tgatgaaaaa tttgacatta ttatgatgaa
     8641 tccacctttt ggagggtcag aattagaaac aataaaaaat aactttccag cagaattacg
     8701 gagttctgaa acagctgatt tatttatggc tgtcattatg tatcgtttga aagaaaatgg
     8761 tcgtgttgga gttattttac ctgatggttt tctatttggt gaaggtgtaa aaactcgctt
     8821 gaaacaaaaa ctggtagatg agttcaactt gcatacgatt attaggttgc ctcatagtgt
     8881 ctttgcaccg tatacaggaa tccatacgaa cattcttttc tttgataaaa caaagaaaac
     8941 agaagaaact tggttttatc gtttagatat gccagatggt tataaaaatt tctcgaaaac
     9001 taagccgatg aagtcagaac acttcaatcc tgttcgtgac tggtgggaaa atcgtgaaga
     9061 gattctggaa ggtaagttct acaaatctaa atcatttaca cctagtgaat tggctgagtt
     9121 gaattataat ttagaccagt gtggctttcc aaaagaggaa gaggaaatct taaatccctt
     9181 tgagttgatt cagaattatc aagcggaaag agcaacttta aatcataaga ttgataatgt
     9241 attagctgat attttgcagt tgttggagga caaataatga caccagaaca acttaaagca
     9301 agtattctcc aaagagcgat ggaagggaaa ttagtgccgc aaaatcccaa tgacgaacct
     9361 gcaagtgaat tattaaagag aattaaagct gaaaaagaaa aacttatcag tgaaggaaaa
     9421 atcaaacgag ataaaaagga aactgagata tttcgtggtg atgatg
//
LOCUS       DAVLAQ010000071         8907 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000071 DAVLAQ010000000
VERSION     DAVLAQ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.071"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            122..277
                     /locus_tag="VXB71_001802"
                     /pseudo
     CDS             122..277
                     /locus_tag="VXB71_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VXB71_001803"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VXB71_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0451874.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VXB71_001804"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VXB71_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0451875.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKANFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VXB71_001805"
     CDS             7614..8792
                     /locus_tag="VXB71_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451876.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2756 a         1862 c         1892 g         2397 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct accagtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cggacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 atcatgagat gaccaaatcc cagatgagtt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagtat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aatcttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggcaaaacc taaaccaagc gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggaa gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaaattgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggtcgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc ggcagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtacttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgtgctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggcaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagtca agcaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgattgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 attgtgtctg tggaaatgcc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat caaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaagc agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaagtggtg
     8581 aagtaccctt ttcaactgaa tacctgtccg atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacca tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataat
//
LOCUS       DAVLAQ010000072         8875 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000072 DAVLAQ010000000
VERSION     DAVLAQ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.072"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(74..397)
                     /gene="tnpB"
                     /locus_tag="VXB71_001806"
     CDS             complement(74..397)
                     /gene="tnpB"
                     /locus_tag="VXB71_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0451877.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(658..957)
                     /locus_tag="VXB71_001807"
     CDS             complement(658..957)
                     /locus_tag="VXB71_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0451878.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1122..1529)
                     /locus_tag="VXB71_001808"
     CDS             complement(1122..1529)
                     /locus_tag="VXB71_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0451879.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            1655..2297
                     /locus_tag="VXB71_001809"
                     /pseudo
     CDS             1655..2297
                     /locus_tag="VXB71_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            2464..2664
                     /locus_tag="VXB71_001810"
     CDS             2464..2664
                     /locus_tag="VXB71_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451880.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            2706..3111
                     /locus_tag="VXB71_001811"
                     /pseudo
     CDS             2706..3111
                     /locus_tag="VXB71_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3342..4049
                     /gene="ccdA2"
                     /locus_tag="VXB71_001812"
     CDS             3342..4049
                     /gene="ccdA2"
                     /locus_tag="VXB71_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0451881.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            4060..4617
                     /gene="sdbB"
                     /locus_tag="VXB71_001813"
     CDS             4060..4617
                     /gene="sdbB"
                     /locus_tag="VXB71_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0451882.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            4991..6382
                     /locus_tag="VXB71_001814"
     CDS             4991..6382
                     /locus_tag="VXB71_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0451883.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            6525..7442
                     /gene="adcAII"
                     /locus_tag="VXB71_001815"
     CDS             6525..7442
                     /gene="adcAII"
                     /locus_tag="VXB71_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0451884.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            7450..>8875
                     /gene="phtD"
                     /locus_tag="VXB71_001816"
     CDS             7450..>8875
                     /gene="phtD"
                     /locus_tag="VXB71_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0451885.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVRDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         2731 a         1619 c         1828 g         2697 t
ORIGIN      
        1 attgatcagg acagtcaaat cgatttctaa caatgtttta gaagtagggg tgtactattc
       61 tagtttaaat ccactatatt tggggagtga tagaaaagcc cttcataagc cagtctactt
      121 gttcaggtgc gagagctttg acatcctttt ctgtactggg ccaagtcagt tttccgttct
      181 caaagcgttt atatagtatc caaaatcctt gaccatccca gtaaagggct ttaaagcggt
      241 ctttacgtcc accacaaaag agaaagactt gaccggagaa aggatccaat tcaaagtggg
      301 ttttaacgag ataagccagt gaatcgattc cttgtatcat atctgtcttg ccacaaacaa
      361 ggtgaacttg acctaaatca cttagttgaa tcatcatagt acaatacttt tcctccgata
      421 attatttttt atctagtata ctggaagttg gggaattagg atagatacct tgttatgacg
      481 cgcttacgta acttgtaact agctgcctag tttgatcttt gcttcttcat tgattagcag
      541 cagatttcaa aatgataaaa acgtataata gtgggtgtag aaactcttgc tactatgcgt
      601 tttattatgg aaagacttat tggactttct ctcaaatcga gtttttactc aattttctta
      661 cttgattggg attgaaattc caattaattt ctctgagtag agtgtcttga tattggcttc
      721 atcaacagag gccttatcaa ttttacgttt caagaaaaat tcttgaatgg tttcgatttc
      781 aggctcacga atagcacggt gtttgtttga gatgaggatt tcatagtgaa gcggagcttg
      841 ggtaaaaata acatctgtat tccctgcaga ataaacctca acaagggttg catcggtact
      901 ttctagctga ctttttacaa gttgcgagtg tgagtttgtc gtattgataa gcttcataat
      961 atttcctccg attttctaat tctattatag cactttttga ataaagtcgc ttgatttata
     1021 ctcaatgaaa ataaaagagc aaactaggaa gctagccgca ggctatactt gagtatggta
     1081 aggcgacgct gatgtggttt gaattttatt ttcgaagagt attagtcaat cttatgctgt
     1141 tttttccaag attcaatggc ccatttatgg ctaccacgtt taaggttttt gatagcctcg
     1201 tcaataggga accaggcaat atgattaaag ttttctagtg gcttttgtac ttctttgaaa
     1261 ggagttgctt catagaggta ggcaggattg tagtagtagg tatcacgatg acgagaatag
     1321 aaatattcgt cagcttgtcc gtaataggta ccaatttctg ctgtgaaacc aagctcttca
     1381 atcaactcac gctttagggc ttcctgatga ttttcacctg cttcaatttc tccacatggt
     1441 aggaaccaag caccatttgg ttcttgaaca agaacaattt gtttttgttc aggattaggg
     1501 ataactgcat atactccata gcgagcaata tagtctgtat tcgctttttt tctccgaaag
     1561 ttgggtttgc cattgcattt tcctcattat ctagtatcgt tattattata gtgaaatgaa
     1621 ccaaaaatag tacacaatgt ggtataatct tcttatggca tattcaatag attttcgtaa
     1681 aaaagttctc tcttattgtg agcgaacagg tagtataaca gaagcatcac acgttttcca
     1741 aatctcacgt aataccattt atggctggtt aaagctaaaa gagaaaacag gagagctaaa
     1801 ccaccaagta aaaggaacaa aaccaagaaa agttgataga gatagactta aaaactatct
     1861 tactgacaat ccagacgctt atttgactga aatagcttct gaatttggct gtcatctaac
     1921 taccatccac tatgcgctca aagctatggg ttacactcga aaaaaagaac cacacctact
     1981 atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc
     2041 tagcacctgt ttagattgac gaaacaggat tcgatactta tttttatcga gaatatggtc
     2101 gctcattaaa aggtcagtta ataagaggca aagtatctgg aagaagatat cagaggattt
     2161 ctttggttgc aggtctaaca aatggtgaat taatcgctcc aatgacttac gaagagatga
     2221 tgacgagcga cttttttgaa gtatggtttc agaagtttct cttaccaaca ttaaccacac
     2281 catcggttat tatagtaaaa tgaaataaga acaggacaaa tcgatcagga cagtaaaatc
     2341 gaattctaac aatgttttag aagtccatat gtactattct agtttcaata taccataact
     2401 gttcctagtc aacctgcaag ccctgtccca gctccaagct cagctccgac tcaagatcct
     2461 agagtggtag caagcgcttc ggctagctca acgagcacac aagctcaaga gcaagttgac
     2521 aagtctgaac ttcgtgcctt gagtcaagag ttagaccaac gcttgaaagc tttggcaaca
     2581 gtatctgatc cgaaaatcga tgcaaccaag gctgtcctcc tagatgctca aaaagctccg
     2641 gaagatagtg ccttgacaga gtaaggtctg catactgcag tagagtctgt gaaggctggg
     2701 ctgccttgga ctctctcaaa gatgtgaaag caaatgctag cgacagcaag cctacacagg
     2761 acaagaagga tgcaaaacaa ggaacggaag atagtaagga ttcagataag atgactgaaa
     2821 caaactcagt tccagcagga gtgattgtgg tcagtctact tgccctccta ggcgtgattg
     2881 ccttctggct aattcgccgt aagaaagagt cagaaatcca gcaattaagc acggaattga
     2941 ccaaggttct aggacagcta gatgcagaaa aaagcggata aaaaagtcct tgccaaagcc
     3001 caaaaccttc tccaagaaac ccttgatttc gtgaaagaag aaaatggctc agcagagaca
     3061 gaaactaaac tagtagagga gcttaaagca atccttgaca aactcaagta aaacatgatt
     3121 tatgaaatgt cagacctaaa agacattttc gttcacaaaa gcagcgacga gtaatccttg
     3181 tcgttgcttt ttggctattt tgggggataa gatccgcctt gactagcaaa agaaaagatt
     3241 ggtccaatag tgcccgatac gattttgcgt agcagaaagc ttacaaataa aattgaatat
     3301 agtaaaatag gattagaatt attaagaaag ttggttcttt attggaaacg atagtatttt
     3361 taatctctgt ttttctagca ggtgttttat cctttttttc tccttgtatt tttcctcttc
     3421 tgccagtcta tgctgggatt ttattggatg atcaagaaag tgcaaaaagc ttttctttgt
     3481 ttgggagaaa ggttctctgg tcaggcttga ttcgaacact ttgctttatc gctggtatct
     3541 ctctcatttt ctttattcta ggctttggtg ctggttactt tggtcatatt ctctatgcaa
     3601 attggtttcg atatggcatg ggagctatta ttatcatttt gggtcttcac cagatggaaa
     3661 tttttcattt gaagaaatta gaagttcaaa aaagttttac ctttaaaaaa tcagactcta
     3721 atcgttattg gtcagctttt ttacttggta ttacctttag ctttggttgg acaccttgta
     3781 ttggtccagt tttaagttct gttttagcac ttgcggcttc tggaggcaat ggcgcttggc
     3841 aaggagcgat ttatactctc atttacactc tgggcatggc ccttcctttc ttggtattgg
     3901 cactagcttc aggtctagtc atgccatatt ttagtaaaat caagcgtcat atgatgctac
     3961 taaagaaaat tggtggtttc ctcattgttt taatgggaat tttgttacta ttaggacaag
     4021 taaatgttct agctggaatt tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct
     4081 ggcttaagtc tcttgtcatt agttgtattg atggcctgtg gtgaggaaga aactaaaaag
     4141 actcaagcag cacaacagcc aaaacaacaa acgactgtac aacaaattgc tgttggaaaa
     4201 gatgctccaa acttcacatt gcaatccatg gatggcaaag aagttaagtt atctgatttt
     4261 aagggtaaaa aggtttactt gaagttttgg gcttcatggt gtggtccatg caagaaaagt
     4321 atgccagagt tgatggaact agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc
     4381 attgcaccag gaattcaagg tgaaaaaatt gttgagcaat tcccacaatg gttccaggaa
     4441 caaggatata aggatatccc agttctttat gataccaaag caaccacctt ccaagcttat
     4501 caaattcgaa gcattcctac agaatattta attgatagcc aaggaaagat tggaaagatt
     4561 caatttggtg ctatcagtaa tgcggatgca gaagcagcat ttaaagaaat gaactagaat
     4621 cgataaaatc tgattacaag atgtagtcag attttggtaa cttctaaaac taacttccag
     4681 tttcccacaa cctagctttt agtatgagaa aaacgcgtga catcagtgga aatccgtctt
     4741 agactaactt ccactggttt tctttttctt gatatataag ggttcaaaag cgaaaagact
     4801 cagaaaaagt gcacgacaaa tagccctaaa acagagtcgt cttagagtaa cttccagttt
     4861 tgggagagag atggaagtta ctttgagaag ttacggtagt cagatttttt tagaaaaaca
     4921 ttttataaat attcacatat ctcctatatt tatggtaaaa tagaatcatc agtttatttt
     4981 ggagtcaaag atgaatatat ttagaacaaa gaatgttagt ttagataaaa cagagatgca
     5041 taggcatttg aagttatggg atttgatttt gctgggtatc ggagccatgg tagggacagg
     5101 cgtctttaca atcacaggta ctgcagctgc aacacttgct ggcccagccc tagtgatttc
     5161 aatcgttatt tctgccttgt gtgtgggatt atcagccctc ttttttgcag aatttgcctc
     5221 gcgagtaccc gctacaggag gtgcctatag ttacctctat gctatcttag gagaattccc
     5281 tgcctggttg gctggttggt taaccatgat ggagttcatg acagccatat caggcgtagc
     5341 ttcgggttgg gcagcttatt ttaaaggctt gctctctcaa tacgggatag cctttcctca
     5401 ggctttaaat ggtaccttta atcctcaagc agggacattt gttgatttat tgcctattct
     5461 tgtcttggtc ttggtgactt cgcttgtttt actaaatgcc aaggcagcct tacgctttaa
     5521 ttcgattcta gttattttga aattttccgc tttagctctc tttgttttag taggaatttg
     5581 gaatattaag tttgataatt ggagcaattt tgctccttac ggttttggac aaatctatgg
     5641 agctagcact ggtattatgg ctggtgcgtc cttgatgttc ttcggttttt tgggatttga
     5701 atccatctct atggctgtag atgaagtcaa gactcctcaa aaaaatattc ctagagggat
     5761 tgtcttatcg ctttctatcg taaccattct ctatgccttg gtgacccttg ttttgactgg
     5821 tgtggttcac tatagtcatt taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt
     5881 tgggattagt tgggcagcca actatgtgtc attagtggct atcttgacct tgattacagt
     5941 ttgtatttcg atgacctatg ccctatcgcg tatgatttac agtttagcac gtgacggctt
     6001 agtgcctgct gcctttaagg aactgacgaa gactagcaag ataccaaaga atgctactat
     6061 cttgacaggt ctagcttcag cagtagcagc aggaatgttc ccactagcca gtattgcagc
     6121 ctttttaaat atttgtacct tagcctactt gatcatgttg gcttatggtc tgattcgctt
     6181 acggaaagaa aaaggaatgc ccaaagctgg ggaatttaaa acaccattgg tacctctgtt
     6241 accaatttta tcgatcatca tttgtttatc cttcatgtta cagtataata tgaatacctg
     6301 gattgctttc ctagttgcgt tgttagtagg aagtattatt tacttcactt atggctataa
     6361 gcattctacc atagaagaat aaagtgaaag tctattgagt tgttgacact cagcagattt
     6421 ttatatgtga aagaaatttc aaattttttc taaaaatatc ttgacagatt aaattttcag
     6481 gagtagaata tttactagtt aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt
     6541 tatttttagt cctgttaagt gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa
     6601 gtcagacagg aaaggggatg aaaattgtga ccagttttta tcctatctac gctatggtta
     6661 aggaagtatc tggtgacttg aatgatgttc ggatgattca gtcaagtagt ggtattcact
     6721 cctttgaacc ttcggcaaat gatatcgcag ccatctatga tgcagatgtc tttgtttacc
     6781 attctcatac actcgaatct tgggcaggaa gtctggatcc aaatctaaaa aaatccaaag
     6841 tgaaggtctt agaggcttct gagggaatga ccttggaacg tgtccctgga ctagaggatg
     6901 tggaagcagg ggatggagtt gatgaaaaaa cgctctatga ccctcacaca tggctagatc
     6961 ctgaaaaagc tggagaagaa gcccaaatta tcgctgataa actttcagag gtggatagtg
     7021 agcataaaga gacttatcaa aaaaatgcgc aagcctttat caaaaaagct caggaattga
     7081 ctaagaaatt ccaaccaaaa tttgaaaaag cgactcagaa aacatttgta acacaacata
     7141 cagccttttc ttatctagcg aagagatttg ggcttaatca acttggtatt gcaggtatct
     7201 ctcctgaaca agaaccaagt ccacgacaac taacagaaat tcaggaattt gttaagacct
     7261 ataaggttaa aacgattttt acagaaagta acgcttcttc aaaagtagct gaaactcttg
     7321 tcaaatcaac aggtgtgggt cttaaaactc tgaatccttt agagtcagac ccacaaaatg
     7381 acaagaccta tttagaaaat cttgaagaaa atatgagtat tctagcagaa gaattaaagt
     7441 gaggaaagaa tgaaaatcaa taaaaaatat ctagcaggtt cagtggcagt ccttgcccta
     7501 agtgtttgtt cctatgaact tggtcgtcac caagctggtc aggttaagaa agagtctaat
     7561 cgagtttctt atatagatgg tgatcaggct ggtcaaaagg cagaaaattt gacaccagat
     7621 gaagtcagta agagagaggg gatcaacgcc gaacaaattg ttatcaagat tacggatcaa
     7681 ggttatgtga cctctcatgg agaccattat cattactata atggcaaggt tccttatgat
     7741 gccatcatca gtgaagaact tctcatgaaa gatccgaatt atcagttgaa ggattcagac
     7801 attgtcaatg aaatcaaggg tggctatgtg attaaggtag acggaaaata ctatgtttac
     7861 cttaaagatg cggcccatgc ggacaatatt cggacaaaag aagagattaa acgtcagaag
     7921 caggaacgca gtcataatca taactcaaga gcagataatg ctgttgctgc agccagagcc
     7981 cagggacgct acaccacaga tgatggttat atctttaatg cttctgatat cattgaggac
     8041 acgggtgatg cttatatcgt tcctcacggc gaccattacc attacattcc taagaatgag
     8101 ttatcagcta gcgagttagc tgctgcagaa gcctattgga atgggaagca gggatctcgt
     8161 ccttcttcaa gttctagtta taatgcaaat ccagttcaac caagattgtc agagaaccac
     8221 aatctgactg tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta
     8281 cgtgaattgt atgctaaacc cttatcagaa cgccatgtgg aatctgatgg ccttattttc
     8341 gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat
     8401 taccacttta tcccttatga acaaatgtct gaattggaaa aacgaattgc tcgtattatt
     8461 ccccttcgtt atcgttcaaa ccattgggta cgagattcaa gaccagaaca accaagtcca
     8521 caatcgactc cagaacctag tccaagtccg caacctgcac caaatcctca accagctcca
     8581 agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cgatggttat
     8641 gtctttgaga agaatggagt ttctcgttat atcccagcca agaatctttc agcagaaaca
     8701 gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa gctaggagct
     8761 aagaaaactg acctcccatc tagtgataga gaattttaca ataaggctta tgacttacta
     8821 gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt tgagg
//
LOCUS       DAVLAQ010000073         8416 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000073 DAVLAQ010000000
VERSION     DAVLAQ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.073"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..220
                     /locus_tag="VXB71_001817"
     CDS             <1..220
                     /locus_tag="VXB71_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0451886.1"
                     /translation="GCLDMVVIQKQNEIEELSTNIEKKIMNYIFEDDGNVSEVIGALD
                     IIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            233..1708
                     /gene="galT"
                     /locus_tag="VXB71_001818"
     CDS             233..1708
                     /gene="galT"
                     /locus_tag="VXB71_001818"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0451887.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKFGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1721..2701
                     /gene="galE"
                     /locus_tag="VXB71_001819"
     CDS             1721..2701
                     /gene="galE"
                     /locus_tag="VXB71_001819"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0451888.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGLPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            2911..3570
                     /locus_tag="VXB71_001820"
     CDS             2911..3570
                     /locus_tag="VXB71_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0451889.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3595..4662
                     /locus_tag="VXB71_001821"
     CDS             3595..4662
                     /locus_tag="VXB71_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0451890.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWGVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4765..5775
                     /locus_tag="VXB71_001822"
     CDS             4765..5775
                     /locus_tag="VXB71_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451891.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5787..7478
                     /locus_tag="VXB71_001823"
     CDS             5787..7478
                     /locus_tag="VXB71_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0451892.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7481..8191
                     /locus_tag="VXB71_001824"
     CDS             7481..8191
                     /locus_tag="VXB71_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0451893.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2850 a         1161 c         1649 g         2756 t
ORIGIN      
        1 tggatgttta gatatggttg ttatacaaaa acagaatgag atagaagagc ttagtacaaa
       61 tattgaaaag aaaataatga attacatatt tgaagatgat gggaatgttt ctgaagtaat
      121 tggtgcttta gatattattc atcaccttga taaaattgct catactacgc aatcaattta
      181 taaatggata atgtatagaa aatatgggaa cataaattag aaagaaaaat atatgaaaac
      241 aattattgat aattttgttg atagagtaat tgaatacgga atgtataatg aaattgacaa
      301 aatatatgtg aaaaatagag tactagcgtt aataggtgag gagggaactg atcgcatttc
      361 cgatgaaaat gacctgaaac aaataaaaga ttacttagtg gaaatcgcct taaaaaacgg
      421 taaaattaaa gatttaatcg aggaaaagga atgtttagga gcagagttaa tgaatttcat
      481 agttccttta cctagtcgat taaatgatat tttttggagt tcatatgata tatcacctca
      541 agaagcagtt gaagagtttt ataagttaag taaagatagt gattatatta aaacttctgc
      601 tattgctaag aatattgagt ttcgagcatc aactaaatac ggagagctag agattacgat
      661 aaatttgtca aaacccgaaa aagatccaaa aacaattgct gctgaaaaat tagtaaaagc
      721 cactaattat cccaaatgtt tactatgtat ggaaaatgaa ggatatcagg ggcgaataaa
      781 ttatccagca cgttcgaatc atagaattat tcgattgaaa tttggtgacg aagtatgggg
      841 attccaatat tctccctact tatactttaa tgagcatgcg atatttttaa atagtcaaca
      901 tgtaccaatg gctattacct ctaaaacatt tgaacaatta ttggagattg ttgatatttt
      961 gccaggatat tttgctggtt caaattctga tcttcctatc tcaggaggct ccattcttag
     1021 tcataaccac taccagggag ggaaacatat tttcccaatg gaaaaagcaa aatttgagag
     1081 tgaatttcgt tttaaagact ttgaggatgt taatgctggt attgtaaaat ggccaatgtc
     1141 agtaattagg ttacaaagtg aaaataaaaa tcgcttgtta gatttagcta ctaaaattct
     1201 aaataagtgg agagaatatt cagatttaga agtagacatc attgctatga ctgaagatgt
     1261 cccacaccat acggtgactc ctattgctcg taaagtggac gggagatatg aattagatat
     1321 tgttctaaga gataatcata ctactgaaca gtacccagat ggtgttttcc atcctcatca
     1381 agatgtacaa catattaaaa aggaaaatat cgggttaatc gaagtgatgg gacttgcgat
     1441 attaccacct cgtttgaaac cagagttaga agaagttgga aaatatcttt taggagagga
     1501 taacgcaatt gcggattatc atttagaatg ggccgaccaa ttgaaagaaa aatatcctcg
     1561 cattaataaa gaagaggtta atagcgtagt tcaacacgaa gcaggacaag tgtttgcgag
     1621 agttctggaa gatgcaggag tttataagaa tacaccgtct gggcatgaag cgtttatgag
     1681 atttgttaag tcggttggaa ttaattagga ggaaacaaaa atggcaatat tggtaacagg
     1741 cggagctggt tatattggta gccataccgt agtagaatta ctaaatttag gaaaggaagt
     1801 catcattgtc gacaaccttt cgaactctag catcttggtg ctagaccgta ttgaagcaat
     1861 tacaggaata cgtcccgtgt tttacgaatt agatgtttgt gataaaccag cattgagaaa
     1921 ggtatttgaa caagaatcga ttgatgctgc aattcatttt gcaggttata aagctgtcgg
     1981 agaatccgtg caaaagcctg tgatgtacta caaaaataat attatgagta cattggcact
     2041 tgttgaagtg atgtcagaat ttaatgttaa aaagattgtc ttttcttcaa gtgcgactgt
     2101 atatggaatt aacaatcagt cacctctaat tgagacgatg caaacaagtg cgacaaatcc
     2161 ttatgggtat acgaaagtga tgcttgagca aattttaaaa gatgttcatg tggcagattc
     2221 agaatggagt attgcgttgc ttcgttattt caatccaatt ggtgctcatg agtctggttt
     2281 gattggggaa gatccctcag gacttcctaa caacttgatg ccttatattg cacaagtagc
     2341 ggtaggtaag ctatcagagc taagtgtgtt cggaaatgat tatgatacgc ttgatggtac
     2401 tggtgtgcgt gattatatcc atgtagtaga tttagcaata ggacatataa aagctttaga
     2461 aaaagtatct gaaaaaacag atgtttatat ctataaccta ggctcgggag aaggcactag
     2521 tgtattacaa cttgtaaata catttgaaag tgttaataag atccctattc cttataaaat
     2581 agttccaaga cgttcaggag acgttgcaac ttgttatgca aatgcagaca aagcatataa
     2641 ggaattaaat tggaggacaa caaaatcgat tgaagacatg tgtagagata catggaatta
     2701 gcaatcaaaa aatcccaatg gctataattg atgatactgt ctatatgagt gctgtatttt
     2761 ggaaaaatta cttaaccttt taatgaaatg catatttaat gaaagataaa ttaaaaaaaa
     2821 tgtttgacag cgcttgacaa aggaaacggt ttcattgtat aatgtaaaca tagtgacacc
     2881 gatgtcaaat ataaaaaaga aggtctttat atgaaaaact taacaaaaat taagttcaaa
     2941 gaaaatgggg aatttaatca tttccctggg aatacagttg tagcaaatct ttatactaaa
     3001 caagatttga tggaagttgt tgatattatt caatcacgtt atagagaatt accatttatc
     3061 gataagttta ctttaactcc aaggaattct attcacatga ctgtaattga attgttgtgc
     3121 catgaaaatc gtgaaacgga gttttggagc agtaatcttc ctctagatac acctttacag
     3181 gaaatacatg attactttgc taaacaactt gaaatttttc cattgttgga tgaagaaatt
     3241 catatgcgta taactgaaat gggaaaacaa aacatactag ttgaacctgc agatgaagct
     3301 tctgcaaaga gattagaaga aattcgtact tatgtctcag aaaaagcagg tgtttgtttc
     3361 cctaatcatg atagatatca attccatatt tcaattgggt atcttcggat tcctctaacc
     3421 gaagaggagg aagaagagtt tactaaagtc agagcagaat taactgaaat tttattagag
     3481 aagattccaa ctattactgt aaaccgtatt gactatactg tatttgaaga tatgagacaa
     3541 tttgttccat atcacgaaaa atttaaataa aataataaaa aaggagaact tatcatgaaa
     3601 aaaatgaaag tttggtctac tgtacttgca acgggagttg ctcttactac acttgctgct
     3661 tgctctggag gttcaaattc tacgactgct tcttcatctg aagaaaaagc tgataaaagt
     3721 caagaattag ttatctattc gaactcagtc tcaaatggtc gtggtgattg gttaactgct
     3781 aaagcaaaag aagctggttt taatataaaa atggttgata tcgctggcgc tcaattagca
     3841 gaccgtgtta ttgctgagaa gaataatgca gttgcagata tggtatttgg aattggtgct
     3901 gttgactcaa ataaaattag agatcaaaaa ttactagtac agtacaagcc taaatggtta
     3961 gataaaattg atcaatcttt atcagataaa gataattatt ataatcctgt gattgttcaa
     4021 ccattagttt taattggggc gcctgatgta aaagaaatgc ctaaagactg gacagagtta
     4081 gctagtaagt ataaaggtaa atattcaatt tatggtcttc aaggtggtac aggacgggca
     4141 attctagcaa gtatcttagt tcgttacctt gatgaaaaag gagatttagg cgtatcagaa
     4201 aaaggatggg gagttgcaaa agaatacttt gcaaatgcct atactcttca aaaaggtgaa
     4261 agctcagttg ttaaagcgtt agataaagaa agcccaattc aatacggtat gatctggggt
     4321 tctggagcgt taatcggaca aaaagaacaa aatgttgaat tcaaagttat gactcctgag
     4381 attggtgtac catttgtaac tgaacaaact atggttttaa gcactagtaa aaaacaagcg
     4441 ttagctaaag aatttattga ttggtttggt caatcagaaa ttcaagtaga atatagtaaa
     4501 aaatttggat ctattcctgc aaataaagat gccctaaaag agttacctga agatacgaaa
     4561 aaatttgttg atcaagtgaa accacaaaat attgactggg aagctgttgg aaagcatttg
     4621 gatgaatggg tagaaaaagc tgaattagaa tacgtaaaat aagaaataag agttattttt
     4681 tatgtccaag tctctctatt atttctaaat ttaaggaaga aataaagaga ggcttttggt
     4741 ttagtaatag agggagttag tgagatgatt aaatttgata atattcaaat taaatatggt
     4801 gattttgttg caattgataa tctgaattta gatatacatg aaggggaatt ctttacattt
     4861 cttgggcctt caggatgtgg taaatcaact actttgagag cattggtagg ttttttagat
     4921 ccatcatcag gaagtattga agttaatgga acagatgtca ctcatttgga acctgaaaag
     4981 cgtggaattg gtattgtatt tcaatcttat gcgctatttc caactatgac tgtttttgat
     5041 aatattgcat ttggtttaaa agttaagaag gtagctccag atgttattaa agctaaagta
     5101 tcagcagtgg cagcaaaaat taagatctct gatcaacagt tacagcgtaa tgtatcagaa
     5161 ttatctgggg gtcaacaaca aagggtagca ttggctcgtg ctctggttct tgaacctaaa
     5221 attctttgtc tagatgaacc attgtcaaac cttgacgcaa aattacgtgt agatttgaga
     5281 aaagagttga aaagacttca aaaagagtta ggtattacta ctttatatgt tactcatgat
     5341 caagaggaag ccttgacttt atctgataga attgcagtct ttaacaatgg atacatcgaa
     5401 caggtcggta caccagtaga gatttatcat aattctcaaa ctgaatttgt atgtgatttt
     5461 attggagata ttaatgtttt gaccgatgaa acagtccacg aagtattact gaaaaataca
     5521 agcgttttct tagaggataa aaaaggttac attcgattag agaaagttcg attcaatcgt
     5581 gaaactgaac aagattttat tctaaaaggg acaattattg atgttgagtt ttctggagtt
     5641 acaattcact atacaataaa agtttctgaa agtcagattc ttaatgtaac aagtattgat
     5701 agtcaggctg ctattagatc tgtcggagaa agtgtggaat tatttatcac accatcagac
     5761 gttctgcaat tttaaggagg tgcagtatgc gtcataaatt aaatttaaaa gattggctta
     5821 ttcgtttagg gttaatctgg ttcttagtaa catttattat ttatccaaac tttgatctag
     5881 tagtgaatgt atttgtaaaa ggaggagaat tttcccttga tgctgtacat cgtgttctaa
     5941 aatctcagag ggcacttcag agtattatga acagttttaa gttagcattt tcactcatta
     6001 ttacagttaa tgtcgtaggt attctttgtg ttctatttac agagtacttt gatattaaag
     6061 gtgctaaaat tttaaaatta ggttatatga cctctttaat ttatggagga gtggttttag
     6121 cgactggata taaatttgtc tatggtcctt atggattgat tacaaaattt ttacaaaatg
     6181 ttatcccttc tttagactct aactggttta ttgggtatgg tgcagtctta ttcattatga
     6241 cattttcagg aactgctaat catacattgt ttttaacaaa tacaattcga agcgttgact
     6301 atcacactat tgaggctgct cgaaatatgg gagcaaaacc atttactgtt ttccgaaaag
     6361 tagtgttacc aaccttaatt ccaactctat ttgcacttac tattatggtt tttcttagtg
     6421 gtttatctgc agtagcagca cccatgattg ttggtggtaa agaatttcaa actataaatc
     6481 caatgattat tacatttgca gggatgggga attctcgtga tttagctgcc ttacttgcaa
     6541 ttattttagg tattgcaact acaattttgc ttactatcat gaataagata gaaaaaggtg
     6601 gaaattatat ttctatctct aagactaaag cgcctcttaa aaaacaaaaa attgcgtcta
     6661 agccttggaa tatcattgct cacattgtag catatggatt gttcacagtt ttcatgcttc
     6721 cactaatttt tatagtatta tactcattta cagatccagt tgcaattcaa acaggtaact
     6781 taacattatc aaactttact ttagaaaatt atcgcttatt ctttagtaat agtgcggcat
     6841 tctctccatt cttggtcagc tttatttatt ctattattgc tgcgacaaca gcaacaattc
     6901 tcgcagttgt atttgctcgt gttgtcagaa aacataaatc tcgttttgat ttcttatttg
     6961 aatatggtgc tctacttcct tggttactac caagtacact tttagcagta agtttattat
     7021 ttacttttaa tcagccacaa tttcttgtct tgaatcagat tttggtaggt agtttggtaa
     7081 ttctacttat tgcatatata gttgtaaaaa tcccattttc ttatagaatg gtacgtgcta
     7141 ttttatttag tgttgatgat gagatggaag atgcagcaag aagtatgggt gcttcacctt
     7201 tttatactat gatgaaggtt atcattccat ttattttacc ggttgttctc tctgttattg
     7261 ctttaaactt taactcttta ttaactgact tcgacttatc tgtattcctt taccatcccc
     7321 tagctcaacc attaggtatt acgattcgat ctgcaggtga tgaaacagca acatctaatg
     7381 cacaagctct ggtatttgtt tatacaattg ttctgatgat catttctgga acggtattat
     7441 acttcacaca aagaccgggg cgtaaagtaa ggaaataatc atgacagcca ctagtcttgg
     7501 gttatcaaat attgaaatag ttgtcaggat tgttttatca gtagtcattg gtagtataat
     7561 tggtttagag agagggagca aatcccagcc tgcaggcatc cgaacttata gtattgtttg
     7621 tctagctgca tgtttgatta tgatgacgaa tgaatacgta tcttataaat ttgggacagg
     7681 agatcctaca cgattaggag ctcaagttat atcaggtgtg ggttttctag gcgctggaac
     7741 gattcttatt acagataaaa agaaaattac aggtctgaca actgcagcag gcatttgggc
     7801 ttcggcagga attggattag ctattggagt aggtttttat gagggagctc ttttagtagc
     7861 catttctgtt tggggtgtga tatccatgtt ccaaccacta aaaaaatatc tgcaaaatcg
     7921 ttctaaaatg attgaattgt atatagtggt taaatctaca gaagcctata atcgtgtatt
     7981 ggtttattgt gcagaaaatg gtatcagaat gaccgattca agaacagcgt ttggagatgt
     8041 taattctgac agaattgaat actttgatgt tccggacaaa aaaatagcgt catttattac
     8101 tctggaatta tcaggtagat ttgaacatct tcgactgatg gaagaaattg ctaatattgt
     8161 aggtgttatt tatgtcgaag aaattagctg aaatttagta aacaaaggga cagatgtttt
     8221 tgtccttttg ttttttagat gttttaatca tctaattttt gagtagattt ttgctcagag
     8281 gtttttatga aagattataa aatcaatttt gatttaggta aaatagaata ttttgataat
     8341 aattgtttga tacaagtata caaatttatt tctttttatg atatttgtga aatggtgttt
     8401 gcctttcatt tacctc
//
LOCUS       DAVLAQ010000074         8098 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000074 DAVLAQ010000000
VERSION     DAVLAQ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.074"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            118..1599
                     /locus_tag="VXB71_001825"
     CDS             118..1599
                     /locus_tag="VXB71_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0451894.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1961..2962
                     /locus_tag="VXB71_001826"
     CDS             1961..2962
                     /locus_tag="VXB71_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0451895.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     KVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3113..4030
                     /locus_tag="VXB71_001827"
     CDS             3113..4030
                     /locus_tag="VXB71_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0451896.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAVRLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4041..4931
                     /locus_tag="VXB71_001828"
     CDS             4041..4931
                     /locus_tag="VXB71_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0451897.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4960..6576
                     /locus_tag="VXB71_001829"
     CDS             4960..6576
                     /locus_tag="VXB71_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0451898.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6586..7905
                     /locus_tag="VXB71_001830"
     CDS             6586..7905
                     /locus_tag="VXB71_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0451899.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
BASE COUNT         2722 a         1270 c         1538 g         2568 t
ORIGIN      
        1 tgttattata cgaaataaaa gattttagga aaagtcgtta tatcatgcta tacctattct
       61 ttgtggtata attgcaagag gtttaatccg ataatttata aagagagaaa gatattcatg
      121 agagatttat tatctaaaaa aagtcatagg caattagaat tattagaatt attatttgaa
      181 cataaacgtt ggtttcatcg ttctgaacta gcagagttat taaattgtac agaacgtgca
      241 gtcaaagatg atctatccca tgttaaatct gcttttcctg acttgatttt tcattcttct
      301 actaatggta tacgcattat taataccgat gatagtgata ttgaaatggt ttaccatcat
      361 ttctttaaac attcaactca tttttcgatt ttagaattca tcttctttaa tgaaggttgt
      421 caagctgaga gtatttgtaa agaattttat atcagttcat cttcgctcta tcgtattatt
      481 agccaaatca ataaagtgat taaaaggcaa tttcaatttg aagtcagtct gacccctgtt
      541 caaatcattg gaaatgagag agacattcgt tacttttttg cacaatattt ttcagaaaaa
      601 tattatttcc tagaatggcc atttgaaaat ttttcatcag agccactatc tcaattgtta
      661 gaattggttt ataaggaaac aagctttcca atgaatttgt caacgcatag aatgctaaag
      721 ttgctcctag ttacgaacct atatagaata aagtttggtc attttatgga agtagataaa
      781 gattctttta acgaccaaag tttggatttt ttaatgcagg cagaaggaat agaaggtgtt
      841 gctcagagtt ttgaatcaga atacaatatc tctttagatg aagaagttgt ttgccaatta
      901 tttgtgtctt actttcaaaa aatgtttttc atagatgaaa gtctctttat gaaatgcgta
      961 aaaaaggata gttatgttga aaaatcttac catctattga gtgattttat tgatcagatt
     1021 tcagtcaagt atcagattga aatggagaat aaggataatc tgatttggca tctgcataat
     1081 accgcacatc tgtatcgtca agagttgttt actgagttta ttttatttga tcaaaaaggg
     1141 aatacaatca ggaactttca aaatattttt ccaaaatttg tttcagatat aaaaaaagag
     1201 ctttctcact atttagagac tcttgaggtt tgttctagtt caatgatggt aaatcatcta
     1261 tcttatacct tcatcactca taccaaacat ttggtgatta atttgctaca aaatcagcct
     1321 aaactaaagg ttttagttat gagtaatttt gatcagtatc atgcaaaatt cgttgcagag
     1381 acactttctt attactgtag caataatttt gaactggaag tttggactga attagaatta
     1441 tcaaaggaat ctttagaaga ttcaccttat gatatcatta tttctaattt tattattcct
     1501 cctattgaaa ataagagact catctattca aataatataa acacggtctc actcatatac
     1561 ttgttaaatg ccatgatgtt tattcgatta gatgagtaac caaaaataac aaaaaaacgc
     1621 tatttcgcgt ttgaactgta cctcaaaagt tagacagaaa aaatctaatt tttggggtgt
     1681 ttttgttaag aaaagacctt caatcattta agcaaaatgt acatctagat ttatagccct
     1741 ctaaaactct tgcttttttt gtagaagata cgaaaaaagc cataaaacca aggcttttcc
     1801 tgttttatgt agatgtttac acatgaaaat tgaagtattt tcaaaagcta attggagtga
     1861 ttttattcat gatgggataa atgatctggc caaaaatgat tgagaaatag ttgcttaaaa
     1921 agcatttgca tgatactata tattgaaagg aggtgataat atggtagaac aaagaaaatc
     1981 aattaccatg aaagatgttg ctttagaagc aggagttagt gttggaactg tttcacgtgt
     2041 aattaataaa gaaaaaggca ttaaagaagt aactttgaaa aaagtggaac aagcgattaa
     2101 aactttgaat tacattccag attactatgc tagaggaatg aaaaaaaatc gaacagaaac
     2161 gattgcaatc attgtaccaa gtatctggca tcccttcttt tcagaatttg ctatgcatgt
     2221 ggaaaatgaa gtctataaga gaaataacaa attactctta tgttctataa atggtacaaa
     2281 tagagagcaa gactatctgg agatgttgcg tcataataaa gttgatggag tggttgccat
     2341 tacctatagt ccaattgaac attacttgac gtcaggaatt ccctttgtta gtattgaccg
     2401 cacatactca gatattgcca ttccttgtgt ttcatcagat aatgatgcag gtggaagaga
     2461 agcagctaaa caattaatta gtaaaggatg tcagcattta gcctttgtgg gcggacataa
     2521 tacaaccatt aatgaaacca aacgtcgtag aatttcattt gaaaagtatg tccaagagca
     2581 taaaatacct cttagtattt ttgatttgga tgagaaagtt actgactatt atggaaagct
     2641 agagagtttc ttggaagaaa attcttctat agatggaatt tttacaatca acgattttac
     2701 agctttggat gtgattgaaa tactagaaaa aaatggcaaa cgtattcctc atgatgtcca
     2761 aattattgga tacgatggaa ttaaaatggc tggagataga gattatctac tttcaactat
     2821 tgaacaacca ttggaagaaa tggcaaaaga agcggttcgt attttgtttg atataattga
     2881 tggaaagact gttaatttgc agacaatcct accagtaaaa tttgttgaag gaaaaacaac
     2941 aaaaaatgaa aataagtctt gacagaaagc gctatcaatg atagaatgaa ttcagataaa
     3001 aagatttatt tttaaaacaa aaatgaaacg tttcaaaaaa agaaataaaa agacagcgcc
     3061 aagcgctatc ttttatagaa aaaatgaaac gtttcaaaaa aaggaggttg ctatgaatag
     3121 caaagcgaag caagtttctc tttgggaaag aatcaagaaa caaaaactct tgttattgat
     3181 gactgtcccc ggtttagttt taacctttat ctttaaatac atccctatgt atggggtttt
     3241 aatcgcattt aaagattaca atcctttaaa aggaatttta gggagtgatt ggattggttt
     3301 ttctgagttt acaaaattca tatcctctcc caactttggt atcttgttag ccaacacatt
     3361 aaaattaagt atctatggtt tattgcttgg ctttttacca ccaatcattc ttgcgattat
     3421 gctcaatcaa ctcttgagtg aaaaagtcaa aaaacgaatt cagctcattt tatacgcacc
     3481 aaactttatc tcagtcgttg ttattgtcgg tatgattttc ctcttctttt cagtgggagg
     3541 accaatcaac aattttcttt ctatgtttgg aatgaaggct gacttcttga caaatccaga
     3601 cttctttaga cccttataca tctttagtgg tatctggcaa ggaatgggct gggcttcaac
     3661 gctctacacg gcaacattgg taaatgtaga tccagcctta gtagaagcag ttcgactgga
     3721 tggagccaat atcttccaac gaatctggca cattgatatt ccagctctta agcctattat
     3781 ggttatccaa tttgttttag ctgcaggtgg aattatgaat gtcggatatg aaaaagcatt
     3841 cttgatgcag acatcgttaa atttgccaac ttctgaaatt atctcgacat atgtctataa
     3901 agttggtctt gtatcaggag actattctta ctcaacagcg gttggtttgt ttaatgcagt
     3961 gattaacgta gtattgcttg ttgcagttaa ccaaatcgtt aaacgcatga ataatggtga
     4021 aggaatttaa ggaggaaagt atgaaaaatt cgattatgga tacaaaattt gatagacgta
     4081 tcttactctt aaataaaatc attattgtct ttatcgtttt gatgactttg cttcctttac
     4141 tttatatcgt cgtagcatcc tttatggatc ctaaggttct ggttagtaga gggattagct
     4201 ttaatccagc cgattggact gtagaaggtt accagcgtgt attcagtgac caatctattc
     4261 taagaggttt tatcaattct ctactatact cttttggatt tgcagcttta acagtattgc
     4321 tatctgtgtt tacagcttat cctctttcta agaaagactt ggttggacgt cgttggatta
     4381 actacttctt gattgtgact atgttctttg gtggtggttt agtcccaact tacttgctcg
     4441 taaaagaatt gggaatgctc aatactccat gggctatcat tgttccaggt gctgtcaatg
     4501 tttggaatat tattcttgct agggcctatt tccaaggatt gcctgaagaa ttagttgaag
     4561 ctgctgtcat tgatggagcg aatgacttgc agattttctt taaaatcatg cttcctcttg
     4621 caaaaccaat tatgtttgtt ctcttcctct atgcttttgt aggacagtgg aactcatact
     4681 ttgatgcaat gatttatatc aaggatccaa acttggaacc attgcaactt gtacttcgta
     4741 aaattctcat tcagagccaa ccaggtcaag acatgattgg agcacaagcg gctatgaatg
     4801 aaatgaaacg tttagctgaa ttgattaaat acgcaactat tgtcatttcc agcttgccat
     4861 tgattgttat gtatccattc ttccaaaaat actttgataa aggaattatg gctggttcac
     4921 ttaaaggata aaaaaagaaa aaataaaagg agttttctca tgaaattcaa aacattctca
     4981 aaatcagcag ttttgttgac agctagttta gcagtacttg cagcctgtgg ctcaaaaaat
     5041 acagcttcaa gtccagatta taagttggaa ggtgtaacat tcccgcttca agaaaagaaa
     5101 acattgaagt ttatgacagc cagttcaccg ttatctccta aagacccaaa tgaaaagtta
     5161 attttgcaac gtttggagaa ggaaactggc gttcatattg actggaccaa ctaccaatcc
     5221 gactttgcag aaaaacgtaa cttggatatt tctagtggtg atttaccaga tgctatccac
     5281 aacgacggag cttcagatgt ggacttgatg aactgggcta aaaaaggtgt tattattcca
     5341 gttgaaaatt tgattgataa atacatgcca aatcttaaga aaattttgga tgagaaacca
     5401 gagtacaagg ccttgatgac agcacctgat gggcacattt actcattccc atggattgaa
     5461 gagcttggag atggtaaaga gtctattcac agcgtcaacg atatggcttg gattaacaaa
     5521 gattggctta agaaacttgg tcttgaaatg ccaaaaacta ctgatgattt gattaaagtc
     5581 ctagaagctt tcaaaaacgg ggatccaaat ggaaatggag aggctgatga aattccattt
     5641 tcatttatta gtggtaacgg aaacgaagat tttaaattcc tatttgctgc atttggtata
     5701 ggggataacg atgatcattt agtagtagga aatgatggca aagttgattt cacagcagat
     5761 aacgataact ataaagaagg tgtcaaattt atccgtcaat tgcaagaaaa aggcttgatt
     5821 gataaagaag ctttcgaaca tgattggaat agttacattg ctaaaggtca tgatcagaaa
     5881 tttggtgttt actttacatg ggataagaat aatgttactg gaagtaacga aagttatgat
     5941 gttttaccag tacttgctgg accaagtggt caaaaacacg tagctcgtac aaacggtatg
     6001 ggatttgcac gtgacaagat ggttattacc agtgtaaaca aaaacctaga attgacagct
     6061 aaatggattg atgcacaata cgctccactc caatctgtgc aaaataactg gggaacttac
     6121 ggagatgaca aacaacaaaa catttttgaa ttggatcaag cgtcaaatag tctaaaacac
     6181 ttaccactaa acggaactgc accagcagaa cttcgtcaaa agactgaagt aggaggacca
     6241 ctagctattc tagattcata ctatggtaaa gtaacaacca tgcctgatga tgccaaatgg
     6301 cgtttggatc ttatcaaaga atattatgtt ccttacatga gcaatgacaa taactatcca
     6361 agagtcttta tgacacagga agatttggac aagattgccc atatcgaagc agatatgaat
     6421 gactatatct accgtaaacg tgctgaatgg attgtaaatg gcaatattga tactgagtgg
     6481 gatgattaca agaaagaact tgaaaaatac ggactttctg attacctcgc tattaaacaa
     6541 aaatactacg atcaatacca agcaaacaaa aactagaggt tgattatggg agataagaaa
     6601 tacacagtag aaaaagccaa tcgttttata gcagaaaata aacatctcgt taatactcaa
     6661 tataagcctg aagaacattt ttcagctgag attggttgga tcaatgatcc aaatggattt
     6721 gtctattttc gtggagaata ccatctcttt tatcaattct atccatatga tagtgtttgg
     6781 gggcctatgc actggggaca tgctaaaagt aaggacttgg tgacttggga gcacttgcca
     6841 gtggcacttg ctcctgacca agattatgac cgaaatggtt gtttctcagg ctctgccatt
     6901 gtcaaggatg atcgcctctg gctcatgtac actggacata tcgaagaaga aaccggtgtc
     6961 cgccaagtgc aaaatatggc attttcagat gacgggattc actttgaaaa gattgaacaa
     7021 aatccagttg caactggatc agacttgcca gatgagttga ttgctgctga ttttcgtgat
     7081 ccaaaactct ttgaaaaaga tggacgctat tactccgtag tagctgccaa acacaagaat
     7141 aatgtgggct gtatcgttct actagggtcc gataacctag tagaatggca gttcgaatcc
     7201 atctttttaa aaggggtaga acaccaaggc tttatgtggg aatgcccaga ttacttcgag
     7261 ttagatggga aagattgcct tattatgtca cccatgcgtt atcagcgtga gggagactca
     7321 tatcataaca tcaactcatc gcttttgttc acgggtaagg tagattgggg agaaaaatgt
     7381 tttatcccag aatcagttca agaaattgat catggccaag acttctatgc gcctcaaaca
     7441 ttgttggacg atcaaaatcg tcgtatcctg attgcttgga tgcagacatg ggggcgtacc
     7501 cttccaaccc atgaccaaga acacaaatgg gcatgtgcca tgactttacc tagaatttta
     7561 agattggaag atggcaaact aagacaattc cctgttaaaa aaggccaata tcaaatccaa
     7621 atagataaag attgtcatta ccacttagga aatgatatag attatcttga atttggttat
     7681 gatagtaatg cgcagcaagt ttacattgat cgtagccatc ttattcaaaa aattctaggt
     7741 gaagaagaac aggacactag tcgacggtat gtagatattg aagctaaaga attggaagtt
     7801 gttctagata aaaattccat cgagattttt gtcaatcaag gtgaagcaag cttgactgca
     7861 acttattact taacggtgcc agctgagcta tcacgaattg attaaaaatt aagttatttc
     7921 tcctaaagaa aaagttctct ttctaaaata gtggaaagag gactttttgt gttttgggta
     7981 tataagctta gtttatggta tttgtaaaat tggtgttgga ttatgattta agctagtttt
     8041 ctaaagaatt tgaaaaaaat tttatttaag caaaaaaaac ccttggttcc aaggcttt
//
LOCUS       DAVLAQ010000075         7951 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000075 DAVLAQ010000000
VERSION     DAVLAQ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.075"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(164..304)
                     /locus_tag="VXB71_001831"
     CDS             complement(164..304)
                     /locus_tag="VXB71_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV0451900.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            473..1015
                     /locus_tag="VXB71_001832"
     CDS             473..1015
                     /locus_tag="VXB71_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0451901.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1015..1644
                     /gene="nth"
                     /locus_tag="VXB71_001833"
     CDS             1015..1644
                     /gene="nth"
                     /locus_tag="VXB71_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0451902.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            1855..2376
                     /gene="pyrR"
                     /locus_tag="VXB71_001834"
     CDS             1855..2376
                     /gene="pyrR"
                     /locus_tag="VXB71_001834"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0451903.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            2395..3318
                     /locus_tag="VXB71_001835"
     CDS             2395..3318
                     /locus_tag="VXB71_001835"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0451904.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            3368..4447
                     /gene="carA"
                     /locus_tag="VXB71_001836"
     CDS             3368..4447
                     /gene="carA"
                     /locus_tag="VXB71_001836"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0451905.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            4758..7934
                     /gene="carB"
                     /locus_tag="VXB71_001837"
     CDS             4758..7934
                     /gene="carB"
                     /locus_tag="VXB71_001837"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0451906.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         2304 a         1608 c         1794 g         2245 t
ORIGIN      
        1 acaggtccat agagacttag tacgtgtttg acatactcgt aatggatttt atcatagttt
       61 cgccaagcag tgcgtgcttg attgtttagt tttaggctac ccagtccaat cagaggactg
      121 gtgggttggt aaaatttctc aagattaatt aagatactgt tgttcaactt ttctgttttt
      181 tgagctcttg catagtagtg tttagcagct cttgtagtcg aatatcatct gccgtaacct
      241 gtttacagtt ttggtagctt ttatttaact tggataggag ttgaatgagt ttcttgtctt
      301 ccatgtgagc atcctccttg atctgatgta ctctttccct atagtatagc actaaaaaat
      361 aaaactatca tagtaaatat gttaaaattt gaattttaat tacaaagttt ggtgtgctga
      421 tttgtagcct tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt
      481 aaatattcaa gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt
      541 agttgatgac ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt
      601 tgggaaagta caatatgaag accgtatgta tttcttagat tatcaactat cttataccat
      661 tgttcttgct tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac
      721 ggaagttttc atggaaggcg caactaacca gctagatcaa gaagttttag atgatgactt
      781 ggtcttgccc atcgaaaatg gggcgcttga ccttgctgag agtgtatcag acaatatcct
      841 gctaaacatt cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttgtctc
      901 aggaaatgac tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa
      961 agaagaaaac agtccttttg ctggcttaca aggactattt gacggagatg aataatggtc
     1021 ttgtcaaaaa aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc
     1081 aagcctagtc ttgattttac caatcatttt gaactcctgg ttgcggtcat gttatcagcc
     1141 cagacgacag atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca
     1201 ccccaagcta tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga
     1261 ttgtatcgga ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt
     1321 gatggtcaag tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag
     1381 acagccaatg ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat
     1441 gtggagcgta tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg
     1501 gaaaagcggg tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg
     1561 atttattttg gaagagccat ttgccatcca aaaaatccag agtgtgacca gtacccacaa
     1621 ttatatgatt ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca
     1681 tgctttgtgc tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg
     1741 caaggagcgc gataaagtag aagggtgaag tctacactgt gtgcagtagg gctcgcttgg
     1801 ctataaattt caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa
     1861 acaaaagaag ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag
     1921 attatcgaac gcaacaaaga tttgaataag atcgtcttgg ctggtattaa aactcgtggt
     1981 gtctttattg cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct
     2041 gttgtggaat tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct
     2101 ttggtttctg tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca
     2161 ggtcgtacca tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg
     2221 agtttagcag ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt
     2281 ggaaaaaata tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat
     2341 gaccaagaca gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca
     2401 gaaaatcaac aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta
     2461 atgaaattga tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac
     2521 catccgattg tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa
     2581 gtcgcagaga ttaaacttgg attggaacga cttgactttg atgtgaagac tagttcggtt
     2641 aataagggtg agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc
     2701 tgtgtgattc gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt
     2761 acgacttcca tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt
     2821 gatttgatga ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca
     2881 ggtgacttgg atcactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga
     2941 gctgaactct ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga
     3001 cagtttgtaa ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg
     3061 caacacgaac gccatgatag tggagctgta ttttcaaaag aagactacca tgcccaacat
     3121 ggcttgactc aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct
     3181 ccaatcaatc gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt
     3241 gtccaacaaa tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg
     3301 agtagaaacg ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg
     3361 tgaaaatatg acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc
     3421 cttcggagca gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta
     3481 ccaagaatcc attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt
     3541 ggtaggaaat tatggtatta atcgtgatga ttatgaatcc attattccaa cttgtaaggg
     3601 agtcgttgtt tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa tgaccttgga
     3661 tgaatttttg aaagccaaga aaattccagg gatttcagga attgatacgc gtgctcttac
     3721 caagattatc cgtaagcatg gtactatgcg tgcaaccttg acccatgttg gggacagtat
     3781 ggaccatgtg acggaccagc tccaagcaac agttttaccg acagacaata tcaaacaggt
     3841 ttctactaaa acgtcttatc cagctccagg agttggtttg agcgtggtgc tagtggactt
     3901 tggtctcaag cactcaatcc tacgtgaact ttctaaacgc aactgtaacg tgacagttgt
     3961 tccttattcg acaacggctg aagaaattct ccatctcaat cctgatggag ttatgttgtc
     4021 aaatggtcca ggtaacccag aagacgttcc acaagcactc gacatgattc gcggtgtaca
     4081 aggaaaaatt ccaatctttg gtatttgtat gggacaccaa ctctttgcaa tggcaaacgg
     4141 ggctaagacc tataagatga agtttggcca tcgtggattc aaccatgcgg tacgtgaaat
     4201 cgcaacagga cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga
     4261 tttgccagag cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt
     4321 gcgccacaga taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc
     4381 acacgacgct agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc
     4441 aaactaagaa cgagtaaaag ctcgtcggag aatttatgta actgaacacg gacggaaagc
     4501 tcagaattta gagaaaccaa cttggattgt caatccttcc ttgatttctt aaaattcaat
     4561 cgctttctat tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa
     4621 ggagaagata cattgttcgc ggaagtgaac acgccctaag aactgtgtga aaaagataaa
     4681 catcgtcttg acgctgaagg cgtcaagacg agtttcctat tttcactgtg ttctttacgg
     4741 gctttgtatc ataaactatg cctaaacgta ctgatattca aaaaattatg gtgattggtt
     4801 ctggtccgat tattattggt caggctgctg agtttgacta cgctgggacc caggcttgct
     4861 tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa ctcaaatcct gcaaccatca
     4921 tgacggacaa ggaaattgct gacaaggttt acattgaacc gattacactt gagtttgtga
     4981 cacgtattct tcgtaaggaa cgtccagatg ccttgctacc aacactcggt ggtcagacag
     5041 gtctcaacat ggccatggaa ttatctaaaa atggtatcct agacgagctt ggcgttgaac
     5101 ttctgggtac caaattatct gccattgacc aagcggagga ccgtgacctc tttaaacaat
     5161 tgatggaaga gcttgagcaa cccattccag aatctgaaat tgttaacaca gtagaagaag
     5221 cagttgcctt tgcagcgaca attggctacc cagtcatcgt tcgtccagcc tttacccttg
     5281 gtggtactgg tggtggtatg tgtgccaacg aaaaagaatt gcgtgaaatc actgaaaatg
     5341 gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg ttcgattgcc ggttttaagg
     5401 aaattgaata cgaagtgatg cgtgactcag ctgacaatgc cttggttgtt tgtaacatgg
     5461 aaaactttga cccagttggg attcacacag gggattccat tgtatttgcc cctgcgcaaa
     5521 ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag cttgagcatt attcgcgccc
     5581 tcaagattga aggtggatgt aatgttcagc tagctcttga tcctaacagc ttcaagtatt
     5641 atgttatcga agtaaaccct cgtgtatcac gttcgtcagc ccttgcttct aaagcgacag
     5701 gatatccgat tgctaagttg gctgccaaga ttgcagtagg tttgaccttg gatgaggtta
     5761 taaacccagt tacaggttca acctatgcca tgtttgaacc agcccttgac tacgtagttg
     5821 ctaagattcc acgtttccca tttgacaagt ttgaaaaggg tgaacgccgt ctcggtacac
     5881 aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa catcgaggaa tctcttctca
     5941 aggcctgccg ctcccttgaa attggggtgc accacaatga aatacctgaa cttgcagcag
     6001 tttctgatga tgccttgatt gaaaaggttg tcaaagccca agatgaccgt ctcttctacg
     6061 tatcagaagc cattcgtcgt ggctacacac ctgaagaaat tgcagagctt acaaaaattg
     6121 atatcttcta tcttgataaa ctcttgcata tctttgaaat tgagcaagaa ttgggtgctc
     6181 atccacaaga tctagaagtt ttgaaaacag ccaaacttaa tggtttctca gaccgtaaga
     6241 ttgctgaact ctggggaacg actgatgatc aagttcgcca acttcgcttg gaaaacaaga
     6301 ttgttccagt ttataagatg gtagatactt gtgcggcaga gttcgactct gaaacgccat
     6361 atttctattc aacctatggt tgggaaaatg aatctatcag atctgataaa gaatctgtac
     6421 ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt tgagtttgac tacgcaaccg
     6481 ttcactctgt taaggctatc caggcagctg gttatgaagc tatcatcatg aactcaaacc
     6541 cagagaccgt ttcaacagac ttctctgtat cagataagct ttactttgag ccattgacat
     6601 tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa gggagttatc gttcagtttg
     6661 gtggtcaaac agccatcaac cttgcggagc cattggcaaa agcaggtgtg accatccttg
     6721 gtacacaggt tgctgaccta gaccgtgccg aagaccgtga cctcttcgag caagctctca
     6781 aagaattgga tattccacag ccaccaggac aaacggctac caatgaagaa gaagcagctc
     6841 ttgcagctcg taagattggc ttcccagttc ttgtccgccc atcttatgta cttggtggac
     6901 gtgccatgga aatcgttgaa aacgaagaag accttcgttc ttacatgcga actgctgtta
     6961 aggctagtcc agatcaccca gttcttgtcg actcttatat cgttgggcaa gagtgcgaag
     7021 ttgatgccat ttcagatggt aaagatgtgc tcattcctgg tatcatggag catatcgaac
     7081 gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc accacaaacc ttgtcgcaaa
     7141 aggttcagga gaccatcgca gactacacca aacgcttagc aatcggtctt cactgccttg
     7201 gaatgatgaa catccagttt gttatcaagg atgaaaaagt ctacgttatt gaggtcaatc
     7261 cacgtgccag ccgtactgtt ccattcctat ctaaggtaac caatattcct atggctcaag
     7321 tagcgaccaa gctcattctt ggtcaaagtt tatcagaact tggctaccaa aatggacttt
     7381 accctgaaag cacccgtgtt catatcaagg cacctgtctt ctcctttacc aaactagcta
     7441 aggtagacag cttgctcggt cctgaaatga agtcaacagg tgaagttatg ggttctgatg
     7501 ctactttgga aaaagctctc tataaagcct ttgaagcttc ttatctacac ttgccaactt
     7561 ttggtaatgt cgtctttacc atcgctgatg atgccaaaga agaagccttg aacttggctc
     7621 gtcgtttcca aaacattggt tatggaatcc ttgcgacaga agggacagca gccttctttg
     7681 ctagtcatgg cttgcaagcc caacctgttg gtaagattgg tgatgacgat aaggatatcc
     7741 caagttttgt acgcaaagga agaattcaag ctatcattaa cacagtagga acaaaacgaa
     7801 ctgctgacga agatggtgag caaattcgtc gttcagccat tgaacacggg gtgcccctct
     7861 tcacagcgct agatacagct aatgccatgc ttaaggtact tgaaagtcgt agctttgtta
     7921 cagaagcgat ttaaatagaa aaataagata t
//
LOCUS       DAVLAQ010000076         7226 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000076 DAVLAQ010000000
VERSION     DAVLAQ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.076"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(98..2356)
                     /locus_tag="VXB71_001838"
     CDS             complement(98..2356)
                     /locus_tag="VXB71_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0451907.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VXB71_001839"
     CDS             complement(2585..2815)
                     /locus_tag="VXB71_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0451908.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VXB71_001840"
     CDS             3005..3688
                     /locus_tag="VXB71_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0451909.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VXB71_001841"
     CDS             3688..4422
                     /locus_tag="VXB71_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0451910.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VXB71_001842"
     CDS             4576..5433
                     /locus_tag="VXB71_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0451911.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5570..6391
                     /locus_tag="VXB71_001843"
     CDS             5570..6391
                     /locus_tag="VXB71_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV0451912.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            6405..>7226
                     /locus_tag="VXB71_001844"
     CDS             6405..>7226
                     /locus_tag="VXB71_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0451913.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKV"
BASE COUNT         2060 a         1323 c         1617 g         2226 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata cggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggtccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc caacttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg agggcaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ttaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatac aatcaggatc cagcttggca tgggattttg
     4861 gttcagttgc cattaccaaa acacattgat gaagaggcgg ttctattggc tattgaccca
     4921 gaaaaggatg tggatggttt ccatcctcta aatatgggac gcctttggtc tggacatcca
     4981 gtcatgattc catcaacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgaa
     5041 ttagaaggta aaaatgcggt tgtcatcggt cgttctaata tcgttggaaa acccatggct
     5101 cagcttcttt tggccaagaa tgcaacagtg actttgaccc actcacgcac ccataatctt
     5161 gctaaggtgg ctgctaaagc agatattctg gtggtcgcaa tcggtcgtgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggta gtcattgacg ttgggatgaa tcgtgatgaa
     5281 aatggtaagc tctgtgggga tgtggattat gaggcagttg ccccacttgc tagctatatt
     5341 acgccagtcc ctggaggtgt cggccctatg accattacta tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaaa atcgctgaag agagtgtatt
     5461 ttctatagct atatttaaaa tggcagaaat gaatattaaa ttttagatat aagattacaa
     5521 aaggaggtct gcgcctcctt tttgttgtat aatggagtga ggtgattaga tgattttaaa
     5581 aatttataat agggaatata gtttacaatg ggatggaata tactacctag cactaattga
     5641 ttatccaaat attcaagagt gggaattaga aaaaattgct aaatttatag cttacgaaaa
     5701 acttcataaa cgtcaaacaa gtattgagtg tgctgattct tgtttaaaaa aagaaatttt
     5761 agattacatc tgtcagcatc cctttctgcc accatttacc cctacagata aaagagtagc
     5821 ctcgacttat gatctacata agaggttagt gacttcagac tactgtagtc atactacgac
     5881 tatagatgca gcgatttcta tctttaaaac aggtcagctc ttatctgctg tgaaagcctt
     5941 taggcgagat gctgaagagt tggttttgga tagtagaaat gctgcatcgg atccgataga
     6001 ttattttgat tatgtcatgt tagggtggtc aaatacaagt tctggttatc gattagcgat
     6061 ggagcgttta ttaggtcgag ctccttcaga gaaagaatta caagacaagt ttattcctgg
     6121 agtgagtttt cattttatct atacagattt gattaaagtt actggttata tttttgatgg
     6181 ctaccatgtt gcaaaaatta aggacatgtt gaatttattt agtgagttgt atatttgtat
     6241 tattccaact cataataaga gccaatttga aaatattatt ccaactaaaa tacaagatag
     6301 ggtgcattat cttgactatg ctggagaaga cttagaagag tggactaaga aagtctatca
     6361 agttgtttta aaacaatcag ataaaggata gttgaggaag aacgatgaaa gtgattgatc
     6421 aagccttact agaaaaagtt attattgaac gttctcgtac tagtcataaa ggagactatg
     6481 gccgtctgct gtttcttggt ggaacttatc cttatggtgg tgccatcatc atggctgctt
     6541 tggcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacagatagg gaaaatattc
     6601 cagccctgca cagccattta cctgaggcta tggccttttc tcttcaagac cagcagttgt
     6661 taaaagagca attggagaag gcagaagttg tcttgctggg gccgggttta cgagacgatg
     6721 cttttggaga agatctagtt aaacaggtct ttgctggctt aagacaaaat cagattttga
     6781 ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt tcctcaagcc
     6841 agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt acgattgaaa
     6901 agcaaaagga agatgcaacg gctagtgccc taacttcctt ccctcaagga acaattttgg
     6961 tggagaaagg ttcagctact cgtatttggc aagctggcca atcagattat taccagttac
     7021 aggttggcgg tccctatcag gcgactgggg gaatgggaga tacgcttgct gggatgattg
     7081 caggatttgc aggccagttt aagcaagcta gtctttacga acgtgtggca gtagcgaccc
     7141 atcttcattc agccatagcc caagaactag ctcaagaaca gtatgtggtt ttgccaacgg
     7201 agattagtaa ttgtcttcct aaagta
//
LOCUS       DAVLAQ010000077         7188 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000077 DAVLAQ010000000
VERSION     DAVLAQ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.077"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(395..1288)
                     /locus_tag="VXB71_001845"
     CDS             complement(395..1288)
                     /locus_tag="VXB71_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451914.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(2039..2269)
                     /gene="blpU"
                     /locus_tag="VXB71_001846"
     CDS             complement(2039..2269)
                     /gene="blpU"
                     /locus_tag="VXB71_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0451915.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(2472..2762)
                     /locus_tag="VXB71_001847"
                     /pseudo
     CDS             complement(2472..2762)
                     /locus_tag="VXB71_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2808..3041)
                     /locus_tag="VXB71_001848"
     CDS             complement(2808..3041)
                     /locus_tag="VXB71_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0451916.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(3047..4039)
                     /gene="plsX"
                     /locus_tag="VXB71_001849"
     CDS             complement(3047..4039)
                     /gene="plsX"
                     /locus_tag="VXB71_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0451917.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4036..4806)
                     /gene="recO"
                     /locus_tag="VXB71_001850"
     CDS             complement(4036..4806)
                     /gene="recO"
                     /locus_tag="VXB71_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0451918.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(4803..5972)
                     /locus_tag="VXB71_001851"
     CDS             complement(4803..5972)
                     /locus_tag="VXB71_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0451919.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6121..7131
                     /locus_tag="VXB71_001852"
     CDS             6121..7131
                     /locus_tag="VXB71_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HEV0451920.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         2049 a         1700 c         1166 g         2273 t
ORIGIN      
        1 tagattatca aattactttt atatcactaa gactcaataa aagataatgt ctatttaact
       61 tttatacgat tactacctcc tttttagttt acacttccta catcataaat aaacatactc
      121 aaccctcaca atctccaaat aactcttcta tatcattgaa aattgagttt catcctctat
      181 actaatgtag gaaacctatt aaaacattcc tttaatccaa tataagaata ccttgttcca
      241 ttaatctcta cccgatatta tagatagaac cagactccta tacttaaaag gacaaataac
      301 gttccaacca taataaacct cctttctttt tgagaacgtt ttctttatag gtttagtata
      361 gcaaaaacat gaaaaaaaca acctgactta gaagtcaggt tgttgggaaa tctatctgtt
      421 tttctgctaa aattctctga actaatacct gatcgtctag caattctgct agagaaatcg
      481 ccttttcata gaaactttct gcctctaaaa tattcttgtc tacaaataaa gcatattttg
      541 cctttagcaa aaatagatga ggtcggtaaa aaacatgtct tgttttagca ataattttct
      601 caaatgtttg aatatatatc agactatctt ctgtctgaat ttggataaat aggctcagaa
      661 gaactttttc catttgaact aggctagcct tatcttcata ttctgaacat agcaatactt
      721 tttgagctaa ctcctcaaaa tgttctttat cttctaatcc catagcacaa caaaagaaat
      781 acaattcaat aatcaacaaa tcatttacag aaaaatattt cttttttaat aactgctgga
      841 aatattcttc cactaaccct aaaccgtagg tcacatctga actaccataa atatcaaaac
      901 gagcttgtgt cacatccaca attaactgct cttcctcagg caaattctca taatagtttt
      961 catatatttc ctcaagtata gcttcttttc gttcgattct tcccttatca gcgtaggttt
     1021 gagaatgaat cagctcatct ttgagtttta ggaatccttt tggaatctct ataaccttaa
     1081 catccacaat attctgtaat gatactccaa gtttatccgc aatcaataat aatttaggaa
     1141 gtgttgctaa agcttgccca ttttcaatac gtgctagctg acgaatcgtc aactctgatt
     1201 catcaccaca aatatctatc tgagtttttc cacaagatcg cctaatagtt ttgattttat
     1261 aaccaatttc acgtttcaac tcatccatag taatactcct taagttgatt acaaagattt
     1321 ctttttcttc ctaattcttt tgtcaatcat atataaaacg ataagcgaaa acagcggtag
     1381 aacaatataa ctcttttcac tcattatcag ctgaaatccc agggttgcta gtatcttaaa
     1441 gatgaaaata ttcatcaaaa atagaaaaac aaatactaaa aaatatttta aaaccttctt
     1501 catttctttt cttcaacttt cctaatttct acacctattt tatcgaaaat atatataaaa
     1561 ctccaaataa acacttcgac tgcacttttt ttggcaaaaa atagacagaa caaacatcct
     1621 atctactaaa aatatgatat gaaaggaaat tgatttttta ctgtcaccct aggcaagctt
     1681 gaaacaaata aatcattgat agtaacactt acgacatcct atttattact tcaatttcta
     1741 atgtctctgc tatttctaag ctacctctgg tatgatctat tcctagtcag aatagataac
     1801 accgttctaa attacgattc atagttactc cttttttgac tcgttactat aagactcctc
     1861 tttacatgcg caaaataatt ttgattcaga ttcatcattt atagttttga ttatttttta
     1921 acagattttt ctgttttctt ctccgaagac tttaaaaatt tttttctaat taaatcatcc
     1981 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
     2041 accaccaaca tgtcgctgca taggccacac ctccaagtat agctcctccc gcagcaccag
     2101 ttgctgcacc ttgccatgtt cttgttttaa ttcctagctg aagacctcgt actgctcctc
     2161 ctccaacacc tgctttggca aaatctcccc aattgcatcc gccaccttca acgcaagcaa
     2221 gcatctcagt atccataatt tcaaattgtg acatcttttt tgtattcata acgaatacct
     2281 cttttttatt tttaatattt gtcttgttac aaacttgaca agtttagtat aacagtatct
     2341 attaattttt ttcatccaaa tcttgaattg gcatcgaaac gtcttgaatt agcttttttg
     2401 tttcaaaatc atctctattt ttaaaaaaga tgttttctaa tcactttttt actattagac
     2461 ttcctgcaaa actagaatcc tagttcatga ttgataatgc cagcaatcaa attcattcgt
     2521 aatccgaagt gtttacgatg atttcgatag gttgttgaaa tcattttaaa cgtttttact
     2581 ttggcaaaga tgttctcaac cttgcttctc tccttggata gcgcatggtt ataggcttta
     2641 tcttcagctg ttagcggctt gagtttgctg gatttacgtg gagtttgtgc ttgaagatat
     2701 atcttcatga gcccttgata accactgtca gccaagattt taccagcttg tccgatattt
     2761 ctcatttcta aaaaccatct acttccgttg acttggaact ccgattacta ttttccttga
     2821 atgattttaa ccacatctcc tacgttttgg agttggtcaa tttcttcatc gctgatttcg
     2881 atactaaatt catcttccag agtcaagata aactccatca agtcaacaga atccgcatcc
     2941 aaatcgtctt tcagactcaa ggattctgtc acgacaaagt cctctccctg tcgctcttgg
     3001 ataatggtca caatacggtc aaaaatttct ttttctgtca tctcttttat tctcctgaaa
     3061 attcacgcgc agtctgggca accacgtctg tttctagcat ggtacggatc tgacgaatcg
     3121 tactataaac agccttggca tcgcttgagc catgagtctt gacaacaggt gctttaacac
     3181 caaacaagac cgctccacca acatctgaat aattgagctg ttttttcaaa ccactgaggc
     3241 tgtccttgag aaggagggca cctagtttcg ctcgaagacc accacctgta atagctgtct
     3301 tgagcaagcc catgattccc atagctgtcc cttcgatgga tttgagcaca gcgtttcccg
     3361 tgaaaccatc tgccacaaca acatctgcaa cgccattcat caaatcacgc gcttccacgt
     3421 ttccgataaa gttcaaactt tcatcagccg ccagtaattc ataagtttcc ttacgaagcg
     3481 ggtcgccctt gctactctct gttccgttgt tgagcaaacc aacgcgtggt tgcgcaatgc
     3541 cacggacatt tttagcatag aaggaaccta gaaccgcata ttgatggagg tgctgggctg
     3601 tattttctgc attagcacca aggtctagca tgtcaaaacc ttttccatca acggtaggca
     3661 aggtagacat gagtccagga cggtcgatat tcttgatacg acccacgatg aagaatcctg
     3721 ctgccaacaa ggcacctgta ttcccagccg aaaggacagc gtctgcttca ccatctttga
     3781 cagccttggc tgccaatacc atactggcat ttttcttatt cctaatagct ctcgtaggtt
     3841 catcatccga atcaatcttc tcatccgtat ggataatgct gacgcgctct gtcgctgtca
     3901 gatattgctt gattttagct tcatctccgt aaagttgaac ctcgatatct gaaaagtcag
     3961 atagggcttg attgacaccc tcaacaatgg cctgaggtgc gtaatcgccc cccatggcat
     4021 ctactgcgat ttttttcatt tcttttcctc ttttagtaat tgtccccagt ctgctaggga
     4081 atcaataaat ttctttgatt ttaggtgaat cccaacgtac tcttcatata gttgatccat
     4141 aaattggcgt agctcttgct tgattccagg cttgagcgaa atggtctcca aagtctcaaa
     4201 atcaatagct tgaaattgat tgagcagata ggggatattg ggattgagat gacaacgtct
     4261 cttatcctca tgataatgct ctggacagag gcaggctcca tatttgaaag aaaagtcaaa
     4321 agcctgacca acccgatggc agaagacaca ctcattaaaa ttgaggctga ttccaaatcg
     4381 agtcaaaatt tgaatttcaa aaatattggt caaaacctga taatccaagc ctgcttccat
     4441 caactccaaa gtcttttgca aaaaagcaaa caagggagca tcctgctgat tgtcctgcaa
     4501 actagcatct gcaagagctg ccacataggt cgcataggcc atgacaaaga ggtcactatt
     4561 aatcttggga aaagtcatga cctcatgata gtcttcgatg taactgagtc cgtcatcatt
     4621 gattcgcaag agaaatcgtg ccagcaccaa gggctgaata acaggcgcca gcttagactg
     4681 accagcgtgt ttgacaaaaa acatgcgttt gccaacctgc tctgtaaaaa ttttgacgag
     4741 cttgtcatcc tcacgaaaat tgcgattgta aagcaccaag ccttgactcg tgatagactg
     4801 aatcatgctt ctctcatgta ctcctcaagt cgtttcatgg cttctttgat agtctccatg
     4861 ctggctgcat aagataggcg gacgtagcct tccccgtaac gtccaaaggc tgcaccaggg
     4921 ataaaggcaa cggccttctt ctgagcaaaa tccttcagaa aagcaaagga gtcttgattg
     4981 tagcccgctg gaattttagc aaaaatatag aaggcaccgt ctggtttgat aatctcaaaa
     5041 ccaagagcag tcattttttc gatgatatag tcccgacgtt ggatatattc cttcttcatg
     5101 ggctccgcat cgtttttacc agccgtcaag gcttctactg cagcatgttg cgccatggta
     5161 tttgcggcag tgaccaagta ctggtgactc ttgattaact gggctgtgaa ggtcgcagga
     5221 gcgaaaatca gccccaaacg ccaacctgtc atggcatgcg atttagacaa accattgata
     5281 ataatagcct ggtctctcaa catcgttcct agagacacat gggcttcgcc tgtgtaggtc
     5341 aattctgagt aaacctcatc acagacaaca aaaatttcgt acttgcgtaa aacagctgcc
     5401 aaggcctcta actgctctcg actgtaggta attcctgtcg gattggctgg atagttgaga
     5461 ataaccgcct tgagcttatc accctgctcc aaaatggcct tctccaacat ctcaggagtc
     5521 aagacaaaac cattttcagt cgtatcaatc tcaacaattt ctgccccaac taagttaaca
     5581 atcggttcat agcctggata agcaggagct ggcaaaagta ccttgtctcc ctcttccaaa
     5641 atagccgtca aagtcgcaga taaagcctct gtcgccccaa ttgtaaccaa gatttcattt
     5701 tcaggagcat agtccagttg gtacttttcc ttaacaaagt cactggctgc ctgacgtaga
     5761 gtcagcagac cactcatccc tgtatagtag gattggttct gatcaatcgc tcgcttggcc
     5821 gcctccttga catggtctgg cgttgtaaaa tcaggttccc ccaaggtcaa acgcaagacc
     5881 ccaggaatct ccgaaataac ctggtcaaac tgacgaatca acgaaacttg aattttatct
     5941 aactgtttat taaagcgctt agttaagtcc atagatacct cctactttca aaacgtatct
     6001 ctattatact acaaaagccc cccgaccgca aaaatacatt agagaatagc tttccacttt
     6061 ctattttact tttcctgttt ataggtctat aatggtaata gattttattt ggaggttttt
     6121 atgtcatttc tatcaaaaaa tggagcaggt atcttggcct gccttctcat ttccatccta
     6181 tcttggtact taggaggatt cttccctgtg attggcgcgc ccgtttttgc cattttcata
     6241 ggcatgctcc tacatccctt tctctcgtcc tataaacaac tggatgctgg tttgaccttt
     6301 agttccaaga agttgctcca atatgccgtt gtcttgcttg gttttggtct caatatctcg
     6361 caggtcttcg cagttggcca atcttcactc cctgtcatcc tgtccactat ctcaatagct
     6421 ctgattattg cctacctctt ccagcgtttc tttgcactgg atacaaaact ggctaccttg
     6481 gttggagtag gttcttctat ctgtgggggt tctgccattg cagcgacagc gcctgttatc
     6541 catgctaagg aaaaggaagt agcccaagcc atttccgtta tctttttctt caatgtcttg
     6601 gctgcgctca tctttccaac cctcggcacc tggcttcatc tatccaatga aggcttcgcc
     6661 ctctttgcag ggactgcggt caacgacact tcctctgtaa cggctgccgc cagcgcttgg
     6721 gacagtcttt accaaagcaa taccctcgag tctgcaacca ttgttaaact cacacgtact
     6781 ttggccatta tccctatcac gctctttcta tcctactggc aaagtcgcca acaagaaaac
     6841 aagcaaagcc tacaactgaa aaaagtcttc ccacttttta tcctttactt tatccttgcc
     6901 tctctcctca ctacactact cacctctcta ggtgtgtcca gtagtttctt tacccctctc
     6961 aaacaactct ctaaattcct tattgtcatg gccatgagtg ctatcggtct caaaaccaat
     7021 ctggtcgcta tggtcaaatc cagtggaaaa tccattgttc ttggagccat ctgctggatt
     7081 gccatcatcc tcaccactct tggtatgcag acccttatcg gcattttcta acactcttcg
     7141 aaaatctctt caaaccacgt caacgtcgcc ttgccgtagg tatatgtt
//
LOCUS       DAVLAQ010000078         7109 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000078 DAVLAQ010000000
VERSION     DAVLAQ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.078"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            226..6660
                     /locus_tag="VXB71_001853"
     CDS             226..6660
                     /locus_tag="VXB71_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0451921.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2785 a          970 c         1369 g         1985 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 acatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctattcgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagact taaagaaact cattaaaaag
     4441 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4501 tataaatacg atgataaggg aaatattatt gcttatgacg atggtagtgc cttacaatat
     4561 gaaactgaaa aacttgacga aataaaatca aaaatttatg gcgttctaag cccatctaaa
     4621 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4681 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgactc acattcaaaa
     4741 acgatgacat ttgatttata cgctaatatt aatgatattg tggatggatt agcttttgct
     4801 ggagatatgc ggttttttgt taaagatgat aatcgaataa aagctgaaac taaaattaga
     4861 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     4921 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     4981 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5041 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5101 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5161 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5221 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5281 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5341 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5401 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5461 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5521 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5581 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5641 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5701 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5761 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5821 ttatatgata atgttaaacc cgaagtaaac attgatccta agggaaatac tagtatcgaa
     5881 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     5941 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6001 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6061 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6121 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6181 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6241 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6301 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagaaaat
     6361 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaacca tagtcaatta
     6421 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6481 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6541 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6601 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6661 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6721 agttttgtga aaacggccat ttataactca attatttagt ttacttcact tcactattga
     6781 tactatttgg agttattaac ggacttagtt tagataacta atgaattgat tgaaagggtt
     6841 agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat ttaaaggcta
     6901 atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta attccttttt
     6961 atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg gttacgatat
     7021 gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg
     7081 ctagcttcct agtttactct ttgattttc
//
LOCUS       DAVLAQ010000079         6967 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000079 DAVLAQ010000000
VERSION     DAVLAQ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.079"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(116..391)
                     /locus_tag="VXB71_001854"
     CDS             complement(116..391)
                     /locus_tag="VXB71_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0451922.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(498..1337)
                     /locus_tag="VXB71_001855"
     CDS             complement(498..1337)
                     /locus_tag="VXB71_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0451923.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1479..2327
                     /locus_tag="VXB71_001856"
     CDS             1479..2327
                     /locus_tag="VXB71_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0451924.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2420..3337)
                     /locus_tag="VXB71_001857"
     CDS             complement(2420..3337)
                     /locus_tag="VXB71_001857"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0451925.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3774..3979
                     /locus_tag="VXB71_001858"
                     /pseudo
     CDS             3774..3979
                     /locus_tag="VXB71_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="VXB71_001859"
     CDS             complement(4290..4583)
                     /gene="rpmA"
                     /locus_tag="VXB71_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0451926.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4600..4944)
                     /locus_tag="VXB71_001860"
     CDS             complement(4600..4944)
                     /locus_tag="VXB71_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0451927.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="VXB71_001861"
     CDS             complement(4960..5274)
                     /gene="rplU"
                     /locus_tag="VXB71_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0451928.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5310..5397)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5456..6160)
                     /locus_tag="VXB71_001862"
     CDS             complement(5456..6160)
                     /locus_tag="VXB71_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0451929.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6562..6861
                     /locus_tag="VXB71_001863"
     CDS             6562..6861
                     /locus_tag="VXB71_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0451930.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2194 a         1413 c         1160 g         2200 t
ORIGIN      
        1 atacaatatt ttcggaacat tcaacttttt aactctattt attactagat ttcataatta
       61 aaaagcctac tgaccaagct agaaagcttg atacaatagg ctttttaaag actgattatt
      121 taacagcgtc tttaagagct ttaccagctt tgaatgctgg tactttagaa gctgcaattg
      181 tcatttcttt accagtttgt gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa
      241 agttaccaaa accgatcaac tgaacttttt caccagctgc aagatagtca gctactgctg
      301 caaatacagc ttcaactgct gctgctgagt ctttcttagt caattctgta gcttctgcta
      361 ctttagcgat caaatcttgt ttgtttgcca tgttaatgat tcctccaaat aatttctaat
      421 taacaaatat aatcatatcc taaaatccct tttaggtcaa gttaaaaacg ctatttcttc
      481 ccattttatt tattttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      541 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      601 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      661 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      721 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      781 cggatattga gaagagagct caacaagcca gttacacggc taattcgtcc acctttgaca
      841 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      901 tgagataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
      961 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1021 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1081 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1141 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1201 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1261 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1321 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1381 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1441 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1501 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1561 cccatcatct ctttgaagga ggggcgacag gcattaccct catcaccttt tatcttttta
     1621 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1681 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccgcct
     1741 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1801 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1861 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1921 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     1981 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2041 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2101 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttctggtc
     2161 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2221 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2281 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2341 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2401 gttttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2461 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2521 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2581 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2641 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2701 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacca
     2761 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2821 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2881 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     2941 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3001 ttgcaaagaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3061 attcttctac accttcgcgc tttaattttc tttcacgttc agcagggttc aaaatatgca
     3121 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3181 cgacgatagg caataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3241 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3301 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3361 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3421 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3481 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3541 tgtcatacta tgttatgtat gaaaaagcaa tgcaactaac tcctgagaac tttaaattac
     3601 taattggtgc caaaaaggta gaatttagaa tcgaggtaca cctatggctg taaaatttac
     3661 aaaatgagac aacttgggca agatgtttga agaatttcct aaactccctg atttgaagca
     3721 agtcactttc cctgatgaca aagaaaaaag ccaaaacagc aaagaaaaac tagatgactg
     3781 ctttccaaca actcccatct agtgtgcttc agactgggct atttttctct ccatctgtta
     3841 gcttggattc tcagaccgtt tcagctaaag aatatctttt cccttatcag aaggaacggc
     3901 tcaaaccatt cagacaagtg aagggacgac aagccaatat ttgaaaccag atagcagttc
     3961 ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg aaactcatat caatttttaa
     4021 cagtgttcta ttccagattc atactcaatg aaaattaaag tgcaaactag gaagttagcc
     4081 gcaggctgta cttgagtacg gcaaggtgaa attgacgtgg tttgaatttg attttcgaag
     4141 agtatcaatc cactatacat attaaaaagt atgggtatca aaataaaaaa acaggctctc
     4201 cgaaaactcg gaaagcctta ttttaagctg tttctagctt cctcaccttt acatttcaag
     4261 gttcgggata aaaggttcaa tgaacctttt tattttgcga ttgggtaaac agaaacttgt
     4321 tttttatcgc gtcctttacg ttcaaagcgt actacgcctt caactttagc gaacaaagta
     4381 tcgtctccac cacgaccaac gtttacacct ggatagatgt gtgtaccacg ttgacggtaa
     4441 aggattgatc cacctgttac agtttgtccg tcagctgctt tagctccaag acgttttgct
     4501 tgtgaatcac gtccgtttga tgtagaacct ccaccttttt tgtgggcgaa aagttgcaag
     4561 ttgttaagag tcatttttaa cataatgttt tcctccgtgt tagttttctg tgataactct
     4621 ggtttggacg aactcagaat agttctccga taagtttgcc atacctaaga aaaatgattc
     4681 aaagaataac tgggtcattt ctctctggtg tgaaggaaga tcttttggta tttcaaccat
     4741 cagatagcca ccttcatctt cgtttaattc taggattggt tcatagcctg caaatttctc
     4801 aatagaattg ataaagttaa tggcaagcgt agaaaccgat gcacacacga catctaagcc
     4861 gtattcgcca ctctcggcgt gtccagtaat ttccgcactc ctcagctcgc catcttcggc
     4921 tctctcaaag actgcctgta tcatgtgttc tccttaaaat taagcgttga ttgcgttgat
     4981 gacaactttt gtatatggtt gacggtgacc ttgtttacgg tggctacctt ttttaggttt
     5041 gtacttgtaa gtaaccactt tcttttgttt tccttgtttt tcaacagttc caactacagt
     5101 agctccagca acaagtggag ttccgacaac agtgttttca ccaccaacaa gaacaacttc
     5161 gttaaaagta acttcttgac cagcttcaac gttcaatttt tcaacgtaaa ctgcttgacc
     5221 aacttcaact ttaacttgtt ttccgccagt tttgataatt gcgtatgtgc tcattatgca
     5281 cctcctatga tttttatggg tttccccgat tttttgtgaa gactcgccta gcatcgtggg
     5341 acgaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca caggatcgtg
     5401 catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat aacacctaaa
     5461 atgaagcttt ttcttttact tttttctgcc aagaggcaaa aagcatgctg aggtaaaaaa
     5521 cgctcatcat aataggaaca ccaagaatgg tcttttcatg atagaaaatc gtcaaatagg
     5581 ctgaaaagac aacgccaagg acaaaactac taagcaggct aacaaatatg aatccttcac
     5641 gcaaaaaagg agtgtgcttg gttcggaaat aatctccaaa agccagcatg gtccgtttga
     5701 tattccctgt cataaaagcg ttattatagg caatacccga cacttctcca aaagcagttg
     5761 tcaccagtcc catacagaag gccaagggcg gcactagata gatattatcc acagtttgcg
     5821 gcacaaaagc aataatgatt gataagattg ccaagggaat caaggacaga ataggttttt
     5881 tcacaattct caatttttcc ttataaatcg ttaataaaaa gactcccatc ataaacgcta
     5941 gcaaggtgag aaccttgtcc ctaacatccg aaacattatt tttaattaat tctactgaaa
     6001 gaaagacaac atttccagtt tgtccagcta caagggtatt cccgcgaaca ataaaagtgt
     6061 aagcatccac atatccagca caaaacgtca aaaaaagtgc taacctttta gactgacgtg
     6121 atatttttct tataggtaat aacctcattt tacctcccat tgtattttct cttagaaata
     6181 ttgtaccatt ttctttctaa aaaatcgtag gctaccattt agattttact attagcataa
     6241 aaataataat agacaactat ttatccaaaa atagatagat gtaacatgtt tgcaaacaaa
     6301 gcatacgaac ctttagtaaa atcatttcca tgaaactaga atagagccct cttagcaaaa
     6361 atcattattt taatttattt ctaatcactc cttgacataa ataactctca ccaataaaag
     6421 actatgtctt aaaaaaatgg tataataaaa tcaatacttg ggcttgatgg ctatgctact
     6481 aataacaatt aggagagaaa atcaggcact tgttaacaac aaggattatc cccttgagat
     6541 gaaaggaact ttagaaatct tatgatgaac atgcaaaaca tgatgcgtca agcacaaaaa
     6601 cttcaaaaac aaatggaaca aagccaagct gaacttgctg ctatgcaatt tgttggcaaa
     6661 tctgctcaag atcttgtcca agcgacctta actggcgata agaaagttgt cagcattgat
     6721 ttcaatccag ctgtcgttga cccagaggac cttgagactc tttctgatat gaccgttcaa
     6781 gccatcaact ctgctcttga acaaatcgat gaaactacca agaaaaaact gggtgctttc
     6841 gctgggaaat tacctttcta aaaacaagga gctagaacaa tgcttgtcga taacaaaggc
     6901 taagaaaggt gcaaaaatga ctctataata tttgtagtgg gtaaatcccc tatagatatt
     6961 atggagc
//
LOCUS       DAVLAQ010000080         6881 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000080 DAVLAQ010000000
VERSION     DAVLAQ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.080"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..436
                     /locus_tag="VXB71_001864"
     CDS             <1..436
                     /locus_tag="VXB71_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0451931.1"
                     /translation="GFDTYFYREYGRSLKGQLRRGKVSGRRYQRISLVAGLTNGELIA
                     PMTYEEMMTSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPL
                     PPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            522..1472
                     /locus_tag="VXB71_001865"
     CDS             522..1472
                     /locus_tag="VXB71_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0451932.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1649..2656
                     /gene="gap"
                     /locus_tag="VXB71_001866"
     CDS             1649..2656
                     /gene="gap"
                     /locus_tag="VXB71_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0451933.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2724..3560)
                     /locus_tag="VXB71_001867"
     CDS             complement(2724..3560)
                     /locus_tag="VXB71_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0451934.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3686..5881
                     /locus_tag="VXB71_001868"
     CDS             3686..5881
                     /locus_tag="VXB71_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0451935.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYNSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5934..6086
                     /gene="rpmG"
                     /locus_tag="VXB71_001869"
     CDS             5934..6086
                     /gene="rpmG"
                     /locus_tag="VXB71_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0451936.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6096..6272
                     /gene="secE"
                     /locus_tag="VXB71_001870"
     CDS             6096..6272
                     /gene="secE"
                     /locus_tag="VXB71_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0451937.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6327..6863
                     /gene="nusG"
                     /locus_tag="VXB71_001871"
     CDS             6327..6863
                     /gene="nusG"
                     /locus_tag="VXB71_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0451938.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2142 a         1197 c         1492 g         2050 t
ORIGIN      
        1 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaagaag
       61 aggtaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg
      121 tgagttaatc gctccaatga cttacgaaga gatgatgacg agcgactttt ttgaagcttg
      181 gtttcagaag tttctcttac caacattaac cacaccatcg gttattatta tggataatgc
      241 aagattccat agaatgggta agttagaact tttatgcgag gagtttgggc ataaactttt
      301 acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa
      361 aaagcacctc aaaaaggtat taccaagttg caataccttt tatgaggctc ttttgtcctg
      421 ctcttgtttc aattgactat agttcacgga tacagttggg aaagaagcta ttaaatattt
      481 ggagagtcct tttgggatga acatgtcaaa tattactata gatgggcaag aaaagatggg
      541 caagaaatgg atctgagtca aacgatgctt cttatgctca agtagtgagt ctttatgatg
      601 atacaagtat ctctgttagt aataatgaga cggacaaagt gttgactgga tccctctata
      661 ctgaaacaaa tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac
      721 agacaggaaa aaatttgaca actaatgatc ttattggcaa atcagtctca gccagcattg
      781 tagaaagtgc tgccgaaact agtaagattg ctcaatttca aacgaagatt gtacgtgtaa
      841 tcaatgatga agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa
      901 cgattttgaa agaggctgga tttacgaaag ctgtatctta ttttatcttg gaactcaaag
      961 atccatcaca gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgc
     1021 tttctcaaca gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat
     1081 tgattgtgct ttcatcacaa gctattgtgg tagcagcggt tatgattggt atcattattt
     1141 acatcaatat catgcaacgt tccaaggaaa taggtgtcat gaaagcagtt ggttatcaga
     1201 atcgtggtgt caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc
     1261 tgctggcatt tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact
     1321 tttacccatc catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag
     1381 ttttcgctct attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa
     1441 tggatcctgt agaatcgtta cgctatgaat aataagggat tccttgattt acagtcttaa
     1501 aaagaaactc acatagaaaa acaatggcca tacttgcaat tcaactcaaa tagttgtata
     1561 ataggtttgt tgaaaggtga tttgtagtga ttcaagttac tcttttcaca ataaaaattt
     1621 catgattttc ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg
     1681 acgtatcggt cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg
     1741 catcaacgac cttacagatc cagttatgct tgcacacttg ttgaaatacg acacaactca
     1801 aggtcgtttc gacggtactg ttgaagttaa agaaggtgga ttcgaagtta acggtaaatt
     1861 cgttaaagtt tctgctgaac gtgatccaga gcaaatcgac tgggctactg acggtgtaga
     1921 aatcgttctt gaagctactg gtttctttgc taagaaagaa gcagctgaaa aacaccttaa
     1981 aggtggagct aaaaaagttg ttatcactgc tcctggtgga aacgacgtta aaacagttgt
     2041 attcaacact aaccacgacg ttcttgacgg tactgaaaca gttatctcag gtgcttcatg
     2101 tactacaaac tgcttggctc caatggctaa agctcttcaa gataactttg gtgttgttga
     2161 aggattgatg actactatcc acgcttacac tggtgaccaa atgatccttg acggaccaca
     2221 ccgtggtggt gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac
     2281 tggtgctgca aaagctatcg gtcttgtaat cccagaattg aatggtaaac ttgatggatc
     2341 tgcacaacgc gttccaactc caactggatc agttactgaa ttggtagcag ttcttgaaaa
     2401 gaacgttact gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg
     2461 ttacacagaa gatccaatcg tatcttcaga tatcgtaggt atgtcttacg gttcattgtt
     2521 tgacgcaact caaactaaag ttcttgacgt tgacggtaaa caattggtta aagttgtatc
     2581 atggtacgac aacgaaatgt catacactgc acaacttgtt cgtactcttg aatacttcgc
     2641 aaagattgct aaataattct tgagttgata gaaagcaagg ctttgtggtc ttgctttttt
     2701 atatggaaaa atggatgaca cgatcatcca ttctttttta attctttttc aaatgtattt
     2761 gaaagggtag tgaaagttag cctctctaaa gtaagtgggt gggtaaagga aagtcggaag
     2821 gcatgaagca taagccggct tgtctttgat ttactattat agagagggtc tcccaggata
     2881 ggaagattat gatgcaaaag gtgcacacga atctgatggg ttcgccctgt ctttagcttg
     2941 caatgagcca aggaagtctt gtttgagaat tgctttaatc tgcttacatg cgtttcagca
     3001 tatttcccat tttttgcatc aactattctt tttctacgat catggcgatc acgtccaatt
     3061 ttgtctctga aaacaagttc ttttctgttg atatttccat caactagagc ccaatattct
     3121 ctagaaatct cttttttctc caataagcga ttgagaatgg gcaggataaa aggatttttg
     3181 gcaaagagaa ctaagccact ggtttccatg tccagacgat gaacgacata gcaggtttgg
     3241 ccaacatagg tactgacatg gttaagaagg gcaatttcgt ttggttgatt accatgcgtt
     3301 ttcatcccct ctggtttgtt tacaataatc aagtgttgat cttgataaac ttcctgcact
     3361 aagtctgggt tgccccaagg gatcgtcttt tggggataat cttcctcgtc aaaagtcaac
     3421 tggcaaacat ctccaggatt tacgatttcg ttccagcgga cttcttcttg atttatcaaa
     3481 atatgtttct tgattctcaa aaaatgacgg atttttctag ggatgaggag ttgttcctca
     3541 agtaattgct ttaccgtcat ttgaggtaga gaggcgggta atgtaaatgt gaattgcata
     3601 cagatattgt aacaaaaaaa gccctatttg gataggaaat agctaaattc ttgtcttcct
     3661 atgatgaaga tgataaaata aacgcatgaa attagataaa ttatttgaga aatttctttc
     3721 tctttttaaa aaagaaacaa gtgaactaga ggactctgat tctactatct tacgtcgctc
     3781 tcgtagtgat cgaaaaaaat tagcccaagt aggtccgatt cgaaaattct ggcgtcgtta
     3841 tcatctaaca aagattatcc ttatactagg tttgagtgca ggcttgctag ttggaatcta
     3901 tttgtttgct gtagccaagt cgaccaatgt caatgatttg caaaatgcct tgaaaactcg
     3961 gactcttatt tttgaccgtg aagaaaaaga ggctggtgcc ttgtctggtc aaaagggaac
     4021 ctatgttgag ctgactgaca tcagtaaaaa cttgcagaat gctgttattg cgacagaaga
     4081 ccgttctttc tataaaaatg acgggattaa ctatggccgt ttcttcttgg ctattgtcac
     4141 tgctggacgt tcaggtggtg gctctaccat tacccaacag ctggctaaaa acgcctattt
     4201 atcgcaggat caaactgttg agagaaaagc gaaagaattt ttccttgcct tagaattaag
     4261 caaaaaatat agtaaggagc aaattctaac catgtacctt aacaacgctt attttggaaa
     4321 tggtgtgtgg ggtgtagaag atgcgagtaa gaaatacttt ggagtttctg catcagaagt
     4381 gagtctggat caagctgcga ctctggcagg gatgctcaag gggccggaac tgtataatcc
     4441 cttgaattcc gtagaagatt ctactaatcg gcgcgatact gtcttgaaga atatggttgc
     4501 agcaggatat attgataaaa accaagaaac cgaagctgct gaagttgata tgacttcgca
     4561 attgcacgat aagtatgaag gaaaaatctc agattaccgt tacccctctt attttgatgc
     4621 ggtggttaat gaagctgttt ccaagtataa tctaacagag gaagagattg tcaataatgg
     4681 ctaccgcatt tacacagagc tggaccaaaa ctaccaagca aatatgcaga ttgtttatga
     4741 aaacacatcg ctatttccga gggcagagga tggaacgttt gctcaatcag gaagtgtagc
     4801 tctcgaaccg aaaacagggg gagttcgtgg agttgtcggt caagttgctg acaatgataa
     4861 aactggattc cggaatttca actatgcaac ccaatcaaag cgtagtcctg gttctacaat
     4921 taagccttta gttgtttata cgccagcagt tgaagcaggc tgggctttga ataagcagtt
     4981 ggataaccat accatgcagt ataacagcta taaggttgat aactatgcag ggatcaaaac
     5041 gagtcgagaa gttcctatgt atcaagcctt ggcagaatcg cttaatctac ctgctgttgc
     5101 cactgttaat gatttgggtg ttgacaaggc ttttgaggca ggcgaaaaat tcggactcaa
     5161 catggaaaag gtcgaccgtg ttcttggtgt cgccttggga agcggtgttg aaaccaaccc
     5221 tcttcaaatg gctcaagcat acgctgcctt tgcaaatgaa ggtttaatgc ctgaagctca
     5281 ttttattagt agaattgaaa atgctagtgg acaagttatt gcgagtcata aaaattcaca
     5341 aaaacgggtg attgataagt ctgtagctga caagatgacc agtatgatgt tggggacttt
     5401 caccaacggt accggtatta gttcatcgcc tgcagactat attatggcag ggaaaactgg
     5461 aacaactgaa gcagttttca atccggagta cacaagtgac cagtgggtaa ttggttatac
     5521 tccggatgta gtgattagcc actggcttgg ctttcctacc actgatgaaa atcactatct
     5581 agctggctct acttcaaacg gtgcagctca tgtctttaga aacattgcca ataccatttt
     5641 accttatacg ccaggaagta cctttacggt tgaaaatgct tataagcaaa atggaattgc
     5701 accagccaat acaaaaagac aagtacaaac caatgataat agccagacag atgataattt
     5761 gtctgatatt cgagggcgtg cgcaaagtct agtagatgag gctagccggg ctatctcaga
     5821 tgcgaagatt aaggaaaagg ctcaaacaat atgggattcg atagtcaatc tatttcgtta
     5881 agatgcttgt caaagcctag ctttcttgtt ataatggata agatggaggc gttatggcac
     5941 taaaaaaagc aagcctagct tgtgcggttt gtggttcgag aaactattca atcaagatca
     6001 gcggaaaccc caagcctaca cgactagaag taaataaatt ttgtaagcat tgtggcaagt
     6061 acactacaca cagagaaacg agataggaga gagcgatgcg ttttattgga gatattttta
     6121 gacttcttaa agacacaaca tggccaactc gcaaggaaag ctggagagat tttcgttcta
     6181 tcatggaata cacagctttc tttgtagtaa ttatttacat ttttgaccag ttgattgttt
     6241 caggtttgat tcgatttatt aacatttttt agaagattag tggagttaat tacactagaa
     6301 atcttctatt tatgaaagga aatatcatgg atagttttga taaaggatgg tttgttttac
     6361 aaacttattc tggttatgaa aataaggtga aagaaaatct attacaacgt gcacaaacct
     6421 acaatatgtt ggataatatt ctacgcgttg aaattccaac acaaacagtg caagttgaaa
     6481 aaaatggaaa gagaaaagaa gtagaagaaa atcgctttcc aggttatgtt cttgtagaaa
     6541 tggtcatgac agatgaagct tggtttgttg ttcgaaacac accaaatgtt acaggatttg
     6601 tcggatcaca cgggaacaga tcaaaaccaa ctccattatt ggaacaagaa attcgtgaca
     6661 ttttggtatc tatgggacaa actgttcaag aatttgattt cgatgttgag attggtcaaa
     6721 ctgtacgtat tattgatggt gcttttgcag actacactgg taagattaca gaaattgata
     6781 ataacaaagt gaaaatgatt atctctatgt ttggtaatga cacagttgca gaagtaaacc
     6841 taaaccaaat cgcagaatta taaccctgag agaggctgga g
//
LOCUS       DAVLAQ010000081         6837 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000081 DAVLAQ010000000
VERSION     DAVLAQ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.081"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            87..3437
                     /locus_tag="VXB71_001872"
     CDS             87..3437
                     /locus_tag="VXB71_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0451939.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3943..4413)
                     /locus_tag="VXB71_001873"
     CDS             complement(3943..4413)
                     /locus_tag="VXB71_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0451940.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4430..6703)
                     /locus_tag="VXB71_001874"
     CDS             complement(4430..6703)
                     /locus_tag="VXB71_001874"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0451941.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2095 a         1149 c         1479 g         2114 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctctgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctttggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaactagct gcaggctgct caaaacactg ttttgaggtt gtagatggaa
     3781 gctgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
     3841 catagtatca agggttttca acacttgata ctatgcgttt tctgatgtta aagactttct
     3901 accaggtttt ttaaaagcat aattgttagt tgtagtcatt tattattctt caaagaaaaa
     3961 tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg catcttcaca
     4021 gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga agctcaaagt
     4081 atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta ggacttggtg
     4141 ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac gtttttccca
     4201 ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc ggacttttga
     4261 taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa tgtcgttctc
     4321 agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga taagagcgcg
     4381 tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt tagcaaggta
     4441 aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg tcacggatgg
     4501 tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct tttagcttgt
     4561 aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta atatcctcta
     4621 ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg actcgttgtg
     4681 cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga ccgttgtcaa
     4741 tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc ccaaattcta
     4801 gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga ttgagctgag
     4861 cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc tgattggctt
     4921 tcccttgata gagctctgta ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct
     4981 tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag gtttcacagt
     5041 tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta ttgtcctgcc
     5101 agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg gtcaataagg
     5161 catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca tgggcaccat
     5221 tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc tggtaaacat
     5281 gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct gcctttactt
     5341 tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc ccagtttttc
     5401 ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg ccacggatat
     5461 agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca aagtcctcac
     5521 ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg taccatgatg
     5581 aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc gcaagaccat
     5641 tggacatggt acctagatag gaaagtcctg ttgtagcaac ttttccgttt gaccaatcag
     5701 ccttgacttg acgctggcgc gtgtgatcag taaaggcacg gcaacggccg ttaagccaat
     5761 cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg aaacctgtcg
     5821 agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga aggaagtagt
     5881 cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct gctataagct
     5941 cagctttacc ttggggttgg acgagattta gttgaggttt ctctagctca atcttgtgag
     6001 gaagtttaac ctcaagctcg ccctccatct tgtagagagc cttgtcacta gccttgtcat
     6061 tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca tcaaaacgag
     6121 ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta tcgacacgag
     6181 actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc aaactcttgc
     6241 cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca agttggtcga
     6301 taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt tcaatcaagt
     6361 caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa
     6421 ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct gctgtcagtt
     6481 catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct aggatagaaa
     6541 gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt
     6601 ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagttca gataagacat
     6661 tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct ccatatagaa
     6721 tgacagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg
     6781 aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag agtaaca
//
LOCUS       DAVLAQ010000082         6471 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000082 DAVLAQ010000000
VERSION     DAVLAQ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.082"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..3315
                     /locus_tag="VXB71_001875"
     CDS             <1..3315
                     /locus_tag="VXB71_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0451942.1"
                     /translation="EGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANS
                     LDAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGS
                     IRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHV
                     TGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHY
                     LFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGAT
                     SGTAWVTGIKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNK
                     DGQRQEALQRYTREESARQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKD
                     IASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNR
                     INSNKQGADNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRK
                     VETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKN
                     SDFKNGTNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDY
                     VLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGE
                     MDNAYIRFDNNGSSSGTADLYITEVDLYKGYKSRTWQPHPEDAVADANKKLEATQTKM
                     TQLAGSWVVENINSAGDIISGINLGANGHNRLVGKLTHITGETLIDRAVIKSAMVDKL
                     KTANFEAGSVTTTILEAEAVTAEKLKVDDALIRKLTAKDAFIDRLTSKRIFSIKVESV
                     ISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGN
                     NWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIEL
                     GSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKIN
                     RLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKA
                     IQELNQKIEKMEKTIA"
     gene            3409..3612
                     /locus_tag="VXB71_001876"
     CDS             3409..3612
                     /locus_tag="VXB71_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451943.1"
                     /translation="MNTEQLNQALRMTISEISTTSTNSMITSNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            3615..3965
                     /locus_tag="VXB71_001877"
     CDS             3615..3965
                     /locus_tag="VXB71_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451944.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            3974..4390
                     /locus_tag="VXB71_001878"
     CDS             3974..4390
                     /locus_tag="VXB71_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0451945.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4394..4726
                     /locus_tag="VXB71_001879"
     CDS             4394..4726
                     /locus_tag="VXB71_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0451946.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKRDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4735..5691
                     /gene="lytA"
                     /locus_tag="VXB71_001880"
     CDS             4735..5691
                     /gene="lytA"
                     /locus_tag="VXB71_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0451947.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHWR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTMADKPEFTVEPDGLITVK"
     gene            complement(5829..6008)
                     /locus_tag="VXB71_001881"
     CDS             complement(5829..6008)
                     /locus_tag="VXB71_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451948.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(6150..6299)
                     /locus_tag="VXB71_001882"
     CDS             complement(6150..6299)
                     /locus_tag="VXB71_001882"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451949.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
BASE COUNT         2082 a         1197 c         1474 g         1718 t
ORIGIN      
        1 gaaggaaccg tttggatttg gatgccgaag tttgaaataa gcgatgtaga tacttcttat
       61 tcagaagctc ctgaagatat agaaggtcag atttcaacag ttgaatcgac cttcaaacaa
      121 cgagccaact cactcgacgc tggtgtaagc cgtctgactg aaggccttag aaccaaagcc
      181 gatatcagct cactcaatgt gactgctgaa aatatccggc aatctgtgaa gagtcttgag
      241 acagacacgc agaacaaact aaatcagaag ttgagtcagg ctgaatttga ggtgcgagct
      301 ggctctatcc gtcaggaaat cctgaacgca accaaggata aagcagataa gactttagtt
      361 gtatctgaag ctgggaaatt gcgagaagaa ttttcaaaaa tgaaggtggg aggccggaat
      421 ctatggataa aatccaagac ggttggagct gtaattgaaa aattacctga aaaccacgtc
      481 acaggtcaaa aagaatgcta taggctagag aacaactcta ctttaacgtt caaccttgaa
      541 ccagatttca gctcaaggtt gtaccaaaaa gttactttta gcgcttggat caagtacgaa
      601 aatgtagtcc aaggtcgaaa tttttggaat gtatttaatt gcttcaaaca ttatcttttt
      661 agaaaaaata gtgagaccgg agtacagagt ggtccagatt atgctacgct tggtatgtat
      721 aaaggttcgg cagattggaa atatattaca ttcacttatg actactctga aaaaacaaat
      781 tttgatcaat tgaagacatc attgcgattc aatcttgaag gtgctacaag cggtacagct
      841 tgggtaacag gaatcaaggt tgaaatcggt agtgtggcga cggactggag tcctgcgcct
      901 gaggacgctg atggtctcat tactgaagct aaggctacct ttgagcggac agctcagggc
      961 ttgcgaaccg acttatcagc tattcaggaa tatgtaaata aagacggtca gcgacaggaa
     1021 gccctacagc gctatactcg tgaggagagc gcgagacaag cgacagcagt ccgtgagctg
     1081 gtcaatcgtg atttcgttgg taaggctact tatcaagaag atgttaaggg tatcaatcaa
     1141 aggattgaag ctgttaaaac tagtgcgaat aaagacatcg ctagtcaaat cgctagctat
     1201 cgtcaatctg tagatggtaa gttcacggat atttcaagtc agataactac ttataagcaa
     1261 gatgtgggcg gtcaaatcag tggcctttca aatagactta caagcagtga gcaaggaacc
     1321 actactcaga tttcaaatct ttcaaatcgg ataaacagta ataaacaagg cgcagataat
     1381 cagatttcaa atttaaagac tcaggtcgct acaaacaagg ataatgctga acgacaaatg
     1441 ggtagaatat ctgatcaggt ttctgcaaac aaagcgaatg ctgatagtca atttgcgaat
     1501 gtgaccaatc aactagtgcg aaaagtagag actactgact tccagcgtgt taaggaaacc
     1561 agtaaacttt acgagcggat tttgggcaat actgaaaatg gaattgcgga taaggttgct
     1621 cgcatggctc tgaccaatca actgtttcag gttgaggttg ggaaatatag tgtaagcggc
     1681 cctaacctca ttaagaatag tgattttaaa aatggtacga atgaatgggg ctcaactcaa
     1741 aatttaggaa gattggttaa gcatagcttt tatcacaacg ggcagaaaga ccttatgcgt
     1801 ttaagtaatg caactaaaaa cgaaaacttt ttgtatagtc accgttttaa tcttgaacga
     1861 aatactgact atgtactgaa ttttagagga tttaacaaca gtgctctagc aagctatgat
     1921 gtttatattt tgggacgaag agcaggcgag agcgatggat tcacaatcgt taagaaagtt
     1981 gttagcagca agaaactatc tacctctaga tgcgaagatg tctcagtaac ttttaattcc
     2041 ggagaaatgg ataatgctta cattcgtttt gataacaatg gctcatcatc aggaacagct
     2101 gatttgtata ttacagaagt tgacttgtac aaaggttata aatctagaac atggcaacca
     2161 catccagaag atgcagtcgc agatgcgaat aagaagcttg aagcaacgca aacaaaaatg
     2221 actcaactag ctggctcatg ggtagttgaa aacatcaact cggctggaga tatcatctct
     2281 ggaatcaatc ttggcgccaa tggacataac cgcttagttg ggaaattgac ccacatcact
     2341 ggagagaccc tgattgacag agcagtcatc aagtctgcca tggttgataa gctcaaaacg
     2401 gccaattttg aagctggttc ggtcacgact acgatattag aagctgaagc ggtaactgct
     2461 gagaagttga aagttgacga tgcgcttatt agaaaattaa ctgcaaaaga tgcttttatt
     2521 gaccgactga catctaaacg tatcttctct attaaggttg agtccgtcat ttctagctca
     2581 accttcctag aagcctatca aggccgaatt ggtggattca cacttggtca atttgaccag
     2641 ggtggcggtc gctggatttc aggtgtcaat cagttctctg ttggtatggg gaatggtgcc
     2701 gggcatggag tccggacagc cttctgggcg aactggggaa ataattggaa ctatgccgga
     2761 cctaaagcat ggaacgtcaa tactgatggg aaaatgtact gtaggaatga agtcggtttt
     2821 tatgatcaag tggatttttc gaattcatcg agagcaaact tctatgggaa tactactttt
     2881 tctcgttctc ctgtgttttc aaatggtatc gaacttggaa gtaaagatgt gcttggtgat
     2941 ggttggaatc ccaaaggcgg aaggaatgcg gttgtttggt ggaatcaggt cggtagcggt
     3001 agcgtgaagt attggatgga acaaaaatca gacagacgct taaaagagaa catcacagat
     3061 acagctgtga aagccttgga caaaatcaac agattaagaa tggttgcatt tgatttcatc
     3121 gaaaataaga aacatgagga gattggtcta atagctcaag aggctgaaac catcgttcca
     3181 agaattgtct cacgagatcc tgagaatcca gatggctatc tacatatcga ctataccgct
     3241 ttagttcctt acttaatcaa ggctattcaa gaattaaatc aaaaaataga aaaaatggag
     3301 aaaacaatag catgaataac aacatgttga ccaatatcgc acttaaagca attcaggagc
     3361 ttgctcttga aaatagaaaa cgaacacaca gattggagaa cttagaaaat gaacacagaa
     3421 cagcttaacc aagccttacg aatgacaatt agtgaaatat caacaacttc aacaaattcg
     3481 atgattacaa gtaatatctt gagtattcag ttggatgagc aaagggaaga aaatcaaaga
     3541 cttcaagcac gagtggatga gctggaagct ctgcttgatg aacaaactaa accagcagac
     3601 aaaggagaat agacatggca gaaacaattc aaaacacaga taacttacta gaccttacaa
     3661 aaatcacaga accatttgat cttgcgagtg ctttgcgcta catgaaagaa aatggagagt
     3721 tcattcgttg caagaatgta agcgatgact tctatatgta tcgtgacgtt caaaaacgtc
     3781 ctgtgattgt aaatggccgt cgccaattca aggatgttga aaccgtttgg gcgttcaatc
     3841 agtggggtgg tacaatcgca acaatcaacg tagccgttct gttgaatcat gaattctata
     3901 tcatgaaatt tgatgcagag ggcaatcctg actggacggt tccaacggta gaacctaaag
     3961 aataggaggt tgtatgcaaa ttgaattttt caattttcta agaagtgtcg tacagactga
     4021 agatggtttg gtattgtacg ctctagcact gattgtctca atggaaatca ttgattttgt
     4081 gacagggacg attgcggcaa ttatcaatcc tgacatcgag tacaagagca aaatcggcat
     4141 taacgggctc cttcgtaaga tttcaggggt tctcttactg atgatcctca ttccggcgtc
     4201 cgttttgttg cctgaaaaga caggttttgc attcttgtac tcaatctatc tcgggtacat
     4261 cgcatttact tttcaatctc tcattgaaaa ttaccgcaaa ttaaaaggaa atgttactct
     4321 ttttcagccg attgtaaaag tatttcagcg attacttgaa aaagatgatg atacgaaaaa
     4381 aggagaataa caaatgcaac aaattactga aatcattact aatggagcaa tcagcatcct
     4441 tgttattttg gcaggggttg tagttagggc agtcaaggaa tacctcgtca aaaaaggtgg
     4501 agaaaagact atcaagattg ttgaaatctt ggccaaaaat gcagtaaatg ccgtggagca
     4561 ggtagctgct gaaactggct acaagagaga tgaaaaactg gcacaggctc gcgctaaagt
     4621 ccgtgctgag cttacaaaat acaatattag catgactgac aaagacttag acaccttcgt
     4681 agagtcagca gtgaagcaga tgaatgacgc atggaaagga cgataggata gggaatggat
     4741 atcgatagaa acagactacg aacaggcttg ccccaggttg gggtgcagcc ttatcgacaa
     4801 gtacacgccc actcaacagg caaccgtaac tcaacagctc aaaatgaggc tgattaccac
     4861 tggcggaaag acccagaatt aggttttttc tcgcacgttg tcggaaatgg ccgtgtcatg
     4921 caggtaggac ctgtgaacaa cggaagttgg gatgttgggg gcggttggaa tgctgagacc
     4981 tatgcagcgg ttgaactgat tgaaagccat tcaactaagg aagagtttat ggctgactat
     5041 cgcctctata tcgaattgct acgcaatcta gcagatgaag caggcttgcc gaaaacgctt
     5101 gatacaggga gtttagctgg aattaaaacg cacgagtatt gcacgaataa ccaaccaaac
     5161 aaccactcag accacgttga cccttatcct tatcttgcaa gttggggcat tagccgtgaa
     5221 cagtttaagc aagacatcga aaacggcttg agcgctgcaa caggctggca gaaaaatggc
     5281 actggctact ggtacgtaca ctcagacggc tcttatccaa aagataagtt tgagaaaatc
     5341 aacggtacct ggtattattt cgatggctca ggctatatgc tttcagaccg ctggaagaag
     5401 cacacagacg gcaactggta ctggttcgac aactcaggcg aaatggctac aggctggaag
     5461 aaaatcgctg acaagtggta ctattttgat gtagaaggtg ccatgaagac aggctgggtc
     5521 aagtacaagg acacttggta ctacttagac gctaaagaag gtgccatggt atcaaatgcc
     5581 tttatccagt cagcggacgg aacaggctgg tactacctca aaccagacgg aacgatggca
     5641 gataaaccag agttcacagt agagccagat ggcttgatta cagtaaaata aatagaaagg
     5701 aaactttcta aattgttctt tcaccgcagg ctcaggcttg cggtttttta tttgctctga
     5761 tttttcaaaa aagtgcttac ttgaagaata gggaggtgtt ttgtcaaaaa taaaaacagt
     5821 gaccgaaatc actgcttatc agttgtagca aattcataaa gtttttctgc tgtgagaagt
     5881 gccattttgt ccatgcttgt ttttcctttt ctgaggtcag aaacagtagt ccatggaact
     5941 ccagcacctt gggaaatagc agatgtagac atcgaactgt ctaacaattc ttgaataact
     6001 tctctcatct tatttgtcct ttttattttt tagataaata tatacattga ttgcaattat
     6061 aaaaatagct attgcactaa ccattgcatt tcctctttcc atttgataaa atagaggtgt
     6121 aaggggcttt cgccccaacc tcttagcgtt tacctttttc tttgacggga tttcggttta
     6181 cgctttttgt tttgccttgc gaccgttatt gcggtcacta gacttgcgat agcagttacc
     6241 gtttcaggaa tattgtctat tgccttttca agtaacctga gccaatcttc tttgttcaac
     6301 ttcatcaccc cctttcctta tcttgattat attatatcac ggtacaccga gaaagtcaag
     6361 cgttttgatg aagttttttt aattttttca aaaaaaatag accttgtcca gaggtcgggg
     6421 agttggaggg ggcaccctcc aaaagcattg atttaataag gttttatttt a
//
LOCUS       DAVLAQ010000083         6374 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000083 DAVLAQ010000000
VERSION     DAVLAQ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.083"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            114..589
                     /locus_tag="VXB71_001883"
                     /pseudo
     CDS             114..589
                     /locus_tag="VXB71_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            627..929
                     /locus_tag="VXB71_001884"
     CDS             627..929
                     /locus_tag="VXB71_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0451950.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEARPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            937..1738
                     /locus_tag="VXB71_001885"
                     /pseudo
     CDS             937..1738
                     /locus_tag="VXB71_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1787..2251
                     /locus_tag="VXB71_001886"
     CDS             1787..2251
                     /locus_tag="VXB71_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0451951.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2408..2833
                     /gene="lacA"
                     /locus_tag="VXB71_001887"
     CDS             2408..2833
                     /gene="lacA"
                     /locus_tag="VXB71_001887"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0451952.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2864..3379
                     /gene="lacB"
                     /locus_tag="VXB71_001888"
     CDS             2864..3379
                     /gene="lacB"
                     /locus_tag="VXB71_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0451953.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3390..4319
                     /locus_tag="VXB71_001889"
     CDS             3390..4319
                     /locus_tag="VXB71_001889"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0451954.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4321..5301
                     /gene="lacD"
                     /locus_tag="VXB71_001890"
     CDS             4321..5301
                     /gene="lacD"
                     /locus_tag="VXB71_001890"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0451955.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5535..6371
                     /locus_tag="VXB71_001891"
     CDS             5535..6371
                     /locus_tag="VXB71_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0451956.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
BASE COUNT         2126 a         1089 c         1320 g         1839 t
ORIGIN      
        1 aaacaaaaca aaaatataaa aaaagagaca aaaaagaaca gaaagtaatt aacaacgatt
       61 tcatatagtg ttatacttat agcataaagt taatggaaag aagggaaaac cttatggtat
      121 tagattattt ctttgacaaa aaccttgtgt tttgcttaga agcggataat caagaataac
      181 tctttgatca ggtagcaagc ttgttggagg aacgagaaat tgtaactcca acttatcgtg
      241 aagctttgat cacgcgtgaa aagtcatttc caactggttt agatatggaa tttctaggaa
      301 aggacttgca aatgtaatga ttcctcacac agatattgtt cataatctag ctgagaaagt
      361 ggtggttgtt cgattagaga aaccggtgac tttccataat atgattgcgc caggtaagga
      421 agtagaagta tccttgctct tctttatcat caataattca agttcaagtc aaacgaacat
      481 tcttgctcag ttgatggact ttttcacagg aaatggacat cttgaagacc tatcaaaaat
      541 ttccgaacca gaaaaacttt atgcttatat agatgaagca atcgcttaat cttgtctatt
      601 aaaaaataaa atcggaggaa gtctatatga ttaaaattct tgctgcctgc ggtgcaggtg
      661 ttaactcaag tcaccaaatt aaaagtgctc tagaagaaga actttcaaac cgtggttacg
      721 atgttcactg tgatgcagtt atggtgaaag atgtaaacga agaccttatg aaaggttacg
      781 atatctttac accaatcgct gcaacagacc ttggttttga accaggtatc ccagttatcg
      841 aagctaggcc aatcttattc cgtatcccag caatgagcgt tccagtattt gacaatatta
      901 gacttcctgc gaaacaaaat atggtatagt agttctatga atgatgaagc aagtaaacaa
      961 ctaactgatg cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg
     1021 ttagctgtat taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa
     1081 ttaagcctag aagaccttct tatggccact cttcaatagt gcgagaatat cgaacttatg
     1141 aacaaattgc ggctgatttt ggtattcacg aaagcaactt tatccgtcgg agccaatggg
     1201 ttgaagtaac tcttgttcaa agtggtgtta cggtttcaag aactcctctc agctctgagg
     1261 acacggtaat gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa gaattagcga
     1321 atgattctgg taaaaagaaa tgccacgcta tgaaggctca agcgattgtc acaagtcaag
     1381 ggagattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt tgttcaaaat
     1441 gagtcgcaga aatatcggac aagctggtaa aatcttggct gacagtggtt atcaagggct
     1501 catgaagata tatcctcaag tacaaactcc acgtaaatcc agcaaactca agccgctaac
     1561 agttgaagat aaaacctata accatgcgct atctaaggag agaagcaagg ttgagaacat
     1621 ctttgccaaa gtaaaaacgt ttaaaatgat ttcaacaacc tatcgaaatc atcgtaaacg
     1681 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
     1741 ttgcaggaag tctaataaag aaactagcaa ggtcaggcct tactttattg gtggacatcc
     1801 aggatttaat tgtcctctac ttgatgatga agtctatgaa gattattatc tagagtttga
     1861 gaaagaagag acttgctctg ttccacgtcc tttcccagaa acaggtatgt tggatttcca
     1921 agatagaagt ccatggctag agggacaaaa agaaatagat cttagttatg atcttttcag
     1981 caaagatgca gtgactttgg atgaattgca atctcgaaca attgcccttc gttctcttaa
     2041 acatgatagg ggattgaaag tgcattttgc agaatttcca aacctcatca tctggtcaac
     2101 tttgaacaag ggacctttca ttacctttga accatggtct ggcttgtcaa cattccttga
     2161 agaaggagat catttagaag ataagaagaa tgtttgtctc ttagaagcca atcaggttga
     2221 agaattaggg tttgagatag aagttttata aaaaagtaaa aaataaataa caaaaacaaa
     2281 cacaaactgt tgacttcttc aaacaatagt agtatattat gtttgtgagg actaattgac
     2341 tgttttttaa agacagccaa tacactgctg gaatccagca tagaaaaaat aaaaaggagt
     2401 atacaatatg tctattgtta tcggtgcaga tgctgcaggt ttgagattga aagaagttgt
     2461 gaaagacttc ttagaaaaag aaaacttcca ccttgtggat gttacagctg aaggtcaaga
     2521 ctttgttgat gtgactctcg ctgttgctgc agaagtaaac aaagaagaac aaaaccttgg
     2581 tatcgtgatt gatgcttatg gagctggtcc atttatggtt gcaactaaga tcaaaggaat
     2641 ggttgctgca gaagtttctg atgaacgttc agcttatatg actcgtggcc acaacaactc
     2701 acgtatgatc actatgggtg cacaacttgt tggtgatgaa ttggctaaaa acatcgctaa
     2761 aggatttgtt aatggtaaat acgacggtgg tcgtcaccaa atccgggttg acatgttgaa
     2821 caaaatgggc taattagatt atagtaagaa aggtaagtta aaaatgagaa ttgcaattgg
     2881 atgtgaccac atcgtaacag atgaaaaaat ggcggtttca gaatttttga aatcaaaagg
     2941 atatgaagtc attgactttg gtacatatga ccatacacgt actcactacc caatctttgg
     3001 taaaaaagta ggggaagctg taactagcgg tcaagctgat cttggagtat gtatctgtgg
     3061 tactggtgtt ggtatcaaca acgctgtaaa taaagttcca ggtgttcgtt ctgccttggt
     3121 tcgtgatatg acaacagccc tttatgctaa agaacaattg aacgctaacg ttattggttt
     3181 tggtggtaaa attactggtg aattgcttat gtgtgatatc atcgaagctt tcatccatgc
     3241 tgaatacaaa ccaactgaag aaaacaaaaa attgattgcg aaaattgaac atgttgaaag
     3301 tcacaatgct caacaaacag acgcaaactt cttcactgaa ttccttgaaa aatgggatcg
     3361 cggagaatac cacgactaag aggtaaccta tgattttaac agttacaatg aacccatcca
     3421 ttgatatttc ctatcccttg gatgagttga agattgatac tgtcaatcgt gtggtggatg
     3481 taaccaaaac ggctggtggt aagggactca atgttacccg agtactttca gaatttggcg
     3541 attctgttct tgctactggt ttagtgggtg gcaaacttgg tgagtttttg gttgaacata
     3601 tcgataatca agtaaagaaa gatttcttct caattcaggg agaaactcgt aactgtatcg
     3661 ctattctcca cggagacaac caaacagaag ttcttgaaaa aggtcctgaa gtattggaac
     3721 aggaaggtca agactttttg gaacatttca aaaaactctt ggagtcagtt gaagtagtgg
     3781 ccatctcagg tagtctgcca gctggccttc cagttgatta ctatgcgagc ttggtagaac
     3841 ttgctaatca agctggcaag cctgtagtct tggactgctc aggtgcagca cttcaggctg
     3901 ttcttgaatc accccataaa ccaacagtca tcaaaccaaa taatgaagaa ttgtctcagc
     3961 ttcttggaag agaagtttct gaggatttgg atgaattaaa agaagtactt caagaacctt
     4021 tgtttgcagg gattgaatgg attatcgttt cacttggtgc caacggtact tttgccaaac
     4081 atggtgacac tttctacaag gtagatattc ctagaattca ggtggtaaat cctgttggat
     4141 ctggagactc tactgtggca ggaatttctt caggacttct tcacaaagaa tcggatgcag
     4201 aattactcat caaggcaaat gtccttggta tgctcaatgc tcaagaaaaa atgactggtc
     4261 atgtcaacat ggccaactat caagttctat atgatcaatt aatagtaaaa gaggtataaa
     4321 atggctttaa cagaacaaaa acgtgtacgc ttagaaaaac tttctgatga aaatggtatc
     4381 atctcagctc ttgcatttga ccaacgtggt gctttgaaac gcctcatggc tcaacaccaa
     4441 acagaagaac caactgtggc ccaaatggaa gaacttaaag tcttggtagc agatgaattg
     4501 actaaatacg cttcatctat gcttcttgac cctgagtatg gacttccagc aactaaagct
     4561 cttgatgaaa aagctggtct tctccttgct tatgaaaaaa caggttatga cacaacaagc
     4621 acaaaacgct tgccagactg cttggatgtc tggtctgcaa aacgtattaa agaagaaggt
     4681 gcagatgcag ttaaattctt gctttactat gatgtagata gctcagacga actcaatcaa
     4741 gaaaaacaag cctacatcga acgcatcggt tctgagtgtg tggctgaaga tatcccattc
     4801 ttccttgaaa ttcttgctta cgatgaaaaa attgcggatg caggttctgt agaatacgcg
     4861 aaagtaaaac cacacaaagt tatcggcgct atgaaagtct tttcagaccc acgctttaac
     4921 attgatgtct tgaaagttga agttcctgtt aacattaaat atgttgaagg cttcgctgaa
     4981 ggtgaagtag tttatacacg tgaagaagca gcagccttct tcaaagcgca agatgaagca
     5041 acgaacttgc catacatcta cttgagtgct ggtgtatcag ctaaactctt ccaagatact
     5101 cttgtatttg ctcatgaatc aggtgcaaac tttaacggag ttctttgtgg ccgtgcaaca
     5161 tgggctggat cagttgaagc atacatcaaa gatggtgaaa cagcagctcg cgaatggctt
     5221 cgcacaactg gatttgaaaa cattgatgag ctcaacaaag ttcttcaaac aacagcaact
     5281 tcatggaaag aacgtgtgta agaaagtcct cctagtttag gaacatgaat ctaaaaaaat
     5341 ttaaaaaaag ttgtatgtaa aggtttacaa aataacttac ttgtgctata cttaaatcac
     5401 aagttaatac aaggtgagtg ttactaagta atattaggca tgatcacagg tgaattagaa
     5461 atcagctgat tttctagttc atttgtggtc attttttgta ctcatatacc tttaagatat
     5521 aaaaggaggt tgacatgtat cgaattctaa atccaatgaa tcacaatgtc tcgcttgtca
     5581 gaaatgataa gggagaagag gtgattgtaa ttggtaaggg gattgcattc ggaaagaaga
     5641 agggggattt gattgctgaa aatcatgttg agaaaatctt tcggatgaag accgaagagt
     5701 ccagagaaaa ctttatggct cttctcaaag atgttccgct tgattttatc acagtgacct
     5761 atgaaatcat tgataagcta tcaaagaaat atcattatcc gattcaagag tatctctatg
     5821 taaccttgac agatcatatt tactgttctt atcaagctct aactcaagga aggtacaagg
     5881 atagtaatct gccagatatt tctgctaagt atcctgtcgc ttttcaaatc gcaaatgaag
     5941 cttttgaaat ttactgtcag aagctagcag atcattttcc tgaggacgaa attattcgga
     6001 ttgcttatca tttcattaat gctgaaggtg aaaatgaagt ggaacttgtg gagtcgattg
     6061 ataagaggaa agaaattctc aggaatgttg aagaagtttt aacggactat gcaattcaac
     6121 gaactaaaaa gaataaccat ttctatgatc gctttatgat ccatttgaat tatttcttgg
     6181 attatttaga cagatctaga gatgataacc aatcacttct ggatatggaa gatcatatta
     6241 aacaatccta tccaaaagcc ttcgagattg gttccaagat ctatgatgtg attacgcaac
     6301 atacgggtct tgatttgtat aaaagtgaac gagtttatct agttctacat atccaacgtt
     6361 tattgtcata aaaa
//
LOCUS       DAVLAQ010000084         5980 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000084 DAVLAQ010000000
VERSION     DAVLAQ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.084"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(1..350)
                     /locus_tag="VXB71_001892"
                     /pseudo
     CDS             complement(1..350)
                     /locus_tag="VXB71_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            370..537
                     /locus_tag="VXB71_001893"
     CDS             370..537
                     /locus_tag="VXB71_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEV0451957.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(692..895)
                     /locus_tag="VXB71_001894"
     CDS             complement(692..895)
                     /locus_tag="VXB71_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451958.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(918..1109)
                     /locus_tag="VXB71_001895"
     CDS             complement(918..1109)
                     /locus_tag="VXB71_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0451959.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            1680..2048
                     /locus_tag="VXB71_001896"
     CDS             1680..2048
                     /locus_tag="VXB71_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0451960.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            2048..2281
                     /locus_tag="VXB71_001897"
     CDS             2048..2281
                     /locus_tag="VXB71_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451961.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            2281..2544
                     /locus_tag="VXB71_001898"
     CDS             2281..2544
                     /locus_tag="VXB71_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0451962.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            2557..2937
                     /locus_tag="VXB71_001899"
     CDS             2557..2937
                     /locus_tag="VXB71_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0451963.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            2954..4024
                     /locus_tag="VXB71_001900"
     CDS             2954..4024
                     /locus_tag="VXB71_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEV0451964.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            4079..5220
                     /locus_tag="VXB71_001901"
                     /pseudo
     CDS             4079..5220
                     /locus_tag="VXB71_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(5303..5396)
                     /gene="ffs"
                     /locus_tag="VXB71_001902"
     ncRNA           complement(5303..5396)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXB71_001902"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5429..5896)
                     /locus_tag="VXB71_001903"
     CDS             complement(5429..5896)
                     /locus_tag="VXB71_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0451965.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
BASE COUNT         2055 a         1248 c          989 g         1688 t
ORIGIN      
        1 aagccatctg gctctactgt gaactctggc ttgtctgcca gtgttccgtc tggtttgagg
       61 tagtaccagc ctgttccgtc cgctgactgg ataaaggcat ttgataccat ggcgccttct
      121 ttagcgtcta agtagtacca agtgtccttg tacttgaccc agcctgtctt catggcacct
      181 tctacatcaa aatagtacca cttgtcagcg attttcttcc agcctgtggc catttcgcct
      241 gattggtcaa agtagtacca attaccgtct gtgtgcttct tccagcggtc tgaaagcata
      301 tagcctgagc catcgaaata ataccagata ccgttgattt tctcaaactt atagaaagga
      361 ggagatagta tggcaaatac tccaataaaa cctggaacag ataatcagaa acctggtcgc
      421 tatgtagagg taggacctcg tggcggaaaa gttactaatg gtcataccgc aactatcgga
      481 aaaggtgatc ggctccctcc gacatctgct aaaggcaacg gttggaaaaa agtctaatct
      541 tcgtttgcgt acaatcgttc aatggttgta cgctttttcc atacacaaaa gcacattccc
      601 aaaaaatcaa tttgaatcca tgcttcggcg taatctttcc cattgctggc atagtgagtt
      661 atataatggt gaatcatttt attccttcct cctattgagt tacttgagaa gtatcatgaa
      721 tggcttcata gctaagacgc ttaaattctt ctgagtctat ctgaaaattg ataggctttt
      781 tttgtaaaca ctcaagaaaa ctagtgtttc ttaaaagttt ttcaactaac tcagggtctg
      841 cctttacaaa ggtggactct ttttgtccac tatacggata tcgttttggt ctcattttcc
      901 tactcctcaa atctttccta ctcaatccca taatcttcaa taacctgaag aatgaaactg
      961 ttcgctcgtg gacctttagt cgttccactt agaatgtttg tcacttcctg tcgtttaaag
     1021 ccgtaagcaa ccgctagagt tgctttttta atgcctttct ctttcaagaa agcaataact
     1081 ctttcgcgac cgtttgcgat atctggcata ttttctcctt tctttttctt tcttcttttt
     1141 ctgctataat ataagcagaa aggagttaac cttatgactt ttaaagaata tttactcaaa
     1201 gcaagcaaac gcgacatcta cgatgatggt aaagattttg agaaatcaat ttcagattct
     1261 cactaatcga gcgtgacttt tttgatatgg caatctcaga aatttaccac cagcgctgac
     1321 taccttaatg actttttcaa ggtggtcttt ttcttgttct aaatttttaa gaatacttac
     1381 catcagcacg ttcctcctct ttacttattt gtaaataaga aacaactaaa aatgtaacta
     1441 tttttctgca ttatacttga caacttacac caaatcggct aaaattaaag cataataaaa
     1501 acaccaataa atctataaat accgttcgcc aaaacatttt tataatttat ttcttagttg
     1561 tttttttagt tgtttatcac ttacaaaaaa cattttacac cttttgggat aattagtcaa
     1621 cctttttaca ccaaatttgt taaatttttt tgtgatgtct tagaaaggtt gatttaacaa
     1681 tgtttgagac atttgaaaaa ataaaagaat tggcaaaaaa gcgtggaaaa gctcttggac
     1741 aagtagaaga agacttaggt tatggtagaa atacactcta taagataaaa aattctacgc
     1801 caaacgctga acgtatcgca gaaattgcta attatttcaa cgtatccacc gactacctgc
     1861 tcggacgaac agataaccct gctatcgctg ggagtgatga atttgcccaa gtaaacggac
     1921 aaatcataga cttacgcaaa gcagcagcca acaccatgtt atttgacggg aaaccactaa
     1981 atgaagatga tatcgacttc attacatccg tcctatccgc ccacttcaaa agcaaaggag
     2041 aacgctaatg actatcacta tcaacttcac agaaaaaaat tcctacatta cggactacct
     2101 aaacaaacac ggtatcgaca caacgaccat ggattttgac gacttcatgg cactcatgga
     2161 agatatcgaa gacgcacgag cagccgacca agcctatatg gagtatttag ccgacccagc
     2221 tacttatacc atggatgagg tcttggatga actaggacta actcgagagg atattgctta
     2281 atgtatcggc tagatattga taaaaaagct ctcaagcaac ttaaaaaact agatacccca
     2341 accagaaaac aaatcctatc ctggcttgct aaaaacattg aaaacacgac caatccacga
     2401 caacacggaa aagcactaaa agccaacctt gcaggttact ggcgatacag agtagagaat
     2461 taccgcatca tctgtgatat ccaagacgat aaactagtcg tcctagccgt ggaaatcgcc
     2521 caccgcagag atgtctataa ataacgaagg agaactatga cactcgctaa actctgcgaa
     2581 gaatatcaag tagaactttg tctcttcgac ggttcaaact ggcacaatag cggtttctac
     2641 aatccagaca caaacgtgct cgctattgac cacaacttga ctcctgaaca acaaatccaa
     2701 gtcgccctac acgaacttgg acacaaagac cacacacgct cagagcacca gaacgcccgt
     2761 ctacgctgtg aaaacgaagc tgataggaat atgatccatc atctcgtaaa agacgctcta
     2821 gaaaacttag acgaccccac agagtttgat tacctcaaat tcatgtctta ctacaatcta
     2881 aaaaccatga caaatgaaat catggttaaa gaagagtatt tagcattagt aaattaaaaa
     2941 aaggagtatc aatatggaaa ttgataaagt aaaagccgat ttaaaacaag tcggcaaacg
     3001 tgtagcagac ctcagccaaa gcattacgaa tgaagaacaa acaaagaatg ccttcattat
     3061 gccgttcttc caagcgcttg gatatgatat cttcaatcca cttgaatttg tcccggaatt
     3121 tactgccgac gtgggcatta aaaaaggcga aaaagtcgac tatgcgatca ttttggatgg
     3181 cgagcctcaa atcctaattg aatgtaaatc aattacagaa aaccttacta agcacgactc
     3241 tcaactattc agatatttcg taactactaa atcaaaattc ggtatcttga caaatggtag
     3301 agaatataaa ttctttactg atttagatga gccaaataaa atggacacaa ctccattctt
     3361 aacaatcgat gtgactgata tcaaagaaaa tcaatttact gaaatcatca aattccacaa
     3421 agagaatttt gatattgata atattgtttc atcagcttct gaattgaaat acctcaacaa
     3481 tcttaaagcg ttccttactg aaaatatcac tacaccgtca gatagcttcc tcagatatct
     3541 aacttctgaa atctatgaag ggcgtgttac tcaaaatatc ttaacgacat tttctcccat
     3601 tattgtgaaa gggtttaatc aattcatcac agagcgagtt aatgaaaaat taagtgctgc
     3661 acttaataca agcgttgaaa ccaaagtaac aaccgatatt ccaaaagttg aagctgaagc
     3721 tgaagagatt gtcgaagtaa ctgacgaaat tatcacaact cctgctgaat tagaagttta
     3781 tactgttgtt aaaatgcttg ctagggatgt agtttctcca gaacgtgtat tttacagaga
     3841 taaccgtagc tatttcaatg ttttggttga cgataacatc aaaaaatggg tattacgtta
     3901 tcgttcaaat tcaaaaaaaa gcactatcga aatccgtgat aaaggcatct tcccggtgtc
     3961 tacccctctc gaagtcgcaa attatgccaa tgaaatttta gaagtaatca agaaattctc
     4021 ataataaaaa aagccctctt tactataccc attttatcaa aaaagtgagg taaaatcaat
     4081 gtggatggaa gaattgccaa acggcaaata taaatttttt gagagataca aagatccata
     4141 tactgagaaa ttaaaaaaag tctcagtaac gatggagaaa aaaactcccc aagcaagaaa
     4201 tcaagctgcg attttacttc aggaaaagat aaaacaaaag ttaggagaaa aacaacattc
     4261 tgtttctaat ataacttttg aaaaactata tgaagaattt gaggagaatt ggaaacacgg
     4321 cgtaaaaaac tcaaccgtct acgcttcaaa gaatgtaaaa aaagagattt taaagcagat
     4381 agagggcgac tacctagtta gaaatttgat agacgtttat tacaaaaagt aatagatcaa
     4441 ctattacaag atgggagatc tcataactat gtttctaaaa tcaaattcaa gctcaatcag
     4501 ataatgaaat ttgctatcag aatgaattat attgatacaa atgaaatgct atttgttgaa
     4561 acgcctagaa aagtaattac atccgacgaa ctcagaaaga aaaatacaaa atacttagac
     4621 caaaaagagt ttaagttatt catccaaaat ttaaaagacg aggccctatg tgattatcga
     4681 attacaaagt atatccgaat agctaaagtt ctttttctta ctggcatgag gtatggagag
     4741 ctggcagcct taaactacaa ggaagatata gatttttcta aaaagactat tcacatcaag
     4801 catacatacg atttcagaca aaaagagaga actacaccaa agacaatcaa gtccgatagg
     4861 gttataacag cacctcaaaa agtgttagat attatcaaag agcaaataat agagaatgcg
     4921 acaaatggat ttgatacaga ttttattttc atcaatactc taggagaacc aataacaaat
     4981 gccagggtta tttgtgcatt gaaaagacat ggtcaaaaaa tcggcataga aaaaaacata
     5041 actacacata catttagaca ttctcacata tccctacttg ctgagctggg cattcccttg
     5101 actgccatca tggacagagt agggcatagt gactcaaaga ccacactaga gatttattct
     5161 cacgttactc aaaaaatggt atcagacata tctagcaagt tagacaagat aaaattttaa
     5221 attgtgcccc tcgtctgccc ctttttctta tacaagacaa acaaaaaccc cttaaagtgt
     5281 tgattttaaa gggtttttaa agtgcacgaa aaaagagcac acaattcaaa tcgcttaggg
     5341 ctgctggatt cctcccctga cccgcttcac gcagaactgt tgctccacta tttattatat
     5401 cacattccta ttcattttaa aagcaaaatt attttttccg tctatttcta aaaaaatcct
     5461 gcatgatagc tgcgcattca tcttccaaaa ttcctatttc aacctccaca cgatgattga
     5521 gacgctcatc tgtcaagata tcgtacaaac tcccagcagc gccaaatttc tggtttttag
     5581 ccccatagac cacatttgga atgcgggcaa gcccaatcgc cccactacac atgacacaag
     5641 gttcaatggt cacaaaaagt gtgcaatcca gcaagcgcca gctctcctca ctcaagttcg
     5701 catcctctat agccataatt tccgcatgca taaccgctcg ctgtaattcc tcacgcgcat
     5761 tatgcccacg accaatgatt tccccatctt tgacaatcac acaaccaatt ggaatttcat
     5821 cgtgttcaag agcaatctca gcctctctca aagcctccct cataaagact tctttttctt
     5881 caagcgtata atacatctct tttctctttt cctacttatc gattttatta ttatatcatg
     5941 aatcccaaca caaaagaagc caccgaatgc ggtgactcta
//
LOCUS       DAVLAQ010000085         5632 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000085 DAVLAQ010000000
VERSION     DAVLAQ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.085"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            76..264
                     /locus_tag="VXB71_001904"
     CDS             76..264
                     /locus_tag="VXB71_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0451966.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            326..1084
                     /locus_tag="VXB71_001905"
     CDS             326..1084
                     /locus_tag="VXB71_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0451967.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            1142..1996
                     /locus_tag="VXB71_001906"
     CDS             1142..1996
                     /locus_tag="VXB71_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0451968.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            2108..2992
                     /locus_tag="VXB71_001907"
     CDS             2108..2992
                     /locus_tag="VXB71_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0451969.1"
                     /translation="MKKAMVIITPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEAIHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKLKED"
     gene            3155..4894
                     /locus_tag="VXB71_001908"
     CDS             3155..4894
                     /locus_tag="VXB71_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0451970.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESASNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            4980..5297
                     /locus_tag="VXB71_001909"
     CDS             4980..5297
                     /locus_tag="VXB71_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451971.1"
                     /translation="MNCRGHETRQRIVRDFEVQPKVHIKLLANQQKHSDAVATIEDEY
                     YVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGS
                     GNL"
     gene            5343..5624
                     /locus_tag="VXB71_001910"
     CDS             5343..5624
                     /locus_tag="VXB71_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451972.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         1890 a          837 c         1190 g         1715 t
ORIGIN      
        1 tttaaactaa tgtattataa aagccagttg acactagtgt tacacctgtg atagaattaa
       61 cttgaggtga tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa
      121 aatctagaga aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta
      181 acaaagtccc aggttattga attactccta aataccgttg attatttcga tgatattatg
      241 ggggctattt actcaaaaaa ataagagcaa aattgctatt attttttaca aattggtgta
      301 acactagtga tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag
      361 tgaggtttca attaataaat acaatgctca agtaggtgcc tacttacaag gagaagaagt
      421 tattttatat caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga
      481 ttatataatg gagactagag cattactaaa aatgatgggc ttaaacgttc cggttcatga
      541 ctatcctatt gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga
      601 gattgtgaat atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt
      661 ctttactgga agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga
      721 ctatcctata tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt
      781 agatggtcgc gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc
      841 aagtgtaatt gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga
      901 tatcggtgtt actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt
      961 gggaaattat ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga
     1021 aatggtaaaa ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttatttt
     1081 ctaaaataaa tatggtagat aaccaatata aaaagcatca aaatgaacaa ggaggaatct
     1141 gatgcttgga gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa
     1201 aacaaaggac tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac
     1261 ctgtgctgtt gcagaagcaa ttatgaatgg tggacaaaaa gatgacttca ttgacgcgat
     1321 gaagaaatat ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct
     1381 aaacagcgat aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc
     1441 tccatgtgct tggatcatgg actgtggttt ttatgcgaaa actggtatat ggccatcatc
     1501 tagaggactt acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg
     1561 cgctatggct acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag
     1621 agagtacgag caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta
     1681 tatagaaaaa gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta
     1741 tcgttttaac gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag
     1801 tagagacttc gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct
     1861 cgcagcaatc acttgtagca tagcagaggc agcttacggt attcctgatt ggatcaagga
     1921 taaggcctat tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag
     1981 aataaaagcg tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata
     2041 ataggattac atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat
     2101 aaaatcaatg aaaaaagcaa tggtaattat cacccctact tctggtggcg agaaggcttt
     2161 ggattacaaa gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa
     2221 aattaccgaa aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta
     2281 tgatgcagtg gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga
     2341 tgagagagac tacattccta agttagggat tatcccaggc ggtacgggta acctcattac
     2401 aaaacttttg gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt
     2461 aaccaataag attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat
     2521 cggttctctg cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat
     2581 tttaacctat gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa
     2641 ggttgagaca gaaaatggaa attatgttgg tgaagctatc catgttttgg tccttttgac
     2701 aaattacttc gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt
     2761 gattctgaaa gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg
     2821 ggatgttgtc gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc
     2881 agatagtgaa ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat
     2941 caaagtccta gctcagcgag tagaagtatt ttcaaaactg aaagaggatt agtatataga
     3001 gaaagccttt tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat
     3061 tccttgcaaa tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg
     3121 taaaatttga atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag
     3181 gcctgagtcg gagtatgcct atctttataa ggataagaaa ctccatattc gaattcgaac
     3241 taagaaaggg gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga
     3301 ggagttttat caggatacaa aagaaatggt caagataact tctggtacct tatttgacca
     3361 ttggcaggtt gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga
     3421 tacagaaggt caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa
     3481 tcttcatgca attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa
     3541 agttcctgac tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa
     3601 tggcaatgct ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa
     3661 gagcgatgat ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca
     3721 agacttgggt attactggac tatatctttg tcccatcttt gaatctgcaa gcaatcacaa
     3781 gtacaatacg acagattact ttgaaattga ccgtcatttt ggagacaagg agacatttcg
     3841 ggaactggtg gatcaagcgc atcatcgtgg catgaaagtc atgctggatg cggtatttaa
     3901 tcatattggt tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggtg aacagtctgc
     3961 ttataaggat tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa
     4021 gagagactta ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc
     4081 caatccagag gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa
     4141 tatcgatgct tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt
     4201 tcgtaaggca gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac
     4261 atctcagcct tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga
     4321 tagtatcaag gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat
     4381 caatggagag tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga
     4441 ttcacatgat acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc
     4501 agccttagcc tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct
     4561 agccttgact ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc
     4621 aagtgacaat gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc
     4681 agtaatcatt tcgcatggca agtatagcct tcaagaaatc aactctgatc tagtagctct
     4741 ggaatggaaa tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta
     4801 tcttttagag aaagaagcag tagcactagc aagcaattgc caagaattgg ataatcagct
     4861 tgtcatctct ccagatggat ttatgatttt ctaaaaacta gttgatgaag attatggtac
     4921 atttcatacc ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa
     4981 tgaattgtag aggacatgaa acaagacaaa gaattgttag agattttgaa gttcagccta
     5041 aagtacatat taagctgtta gcaaatcaac aaaaacatag tgatgcagta gcaactattg
     5101 aagatgaata ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc
     5161 agtgttgcat gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc
     5221 tttttaatcc gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag
     5281 ggagtggaaa tttataacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta
     5341 taatgtggtt gattatttta tggaatgcta agccggatac acctttattt aattttaaag
     5401 acgaagtaat taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata
     5461 ctactataaa gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag
     5521 cggataacga tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg
     5581 atatgaaaga ccaacaagga aatacaatgg aatcttactt ttagttattg tt
//
LOCUS       DAVLAQ010000086         5587 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000086 DAVLAQ010000000
VERSION     DAVLAQ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.086"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(209..1177)
                     /locus_tag="VXB71_001911"
     CDS             complement(209..1177)
                     /locus_tag="VXB71_001911"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0451973.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1322..2105)
                     /locus_tag="VXB71_001912"
                     /pseudo
     CDS             complement(1322..2105)
                     /locus_tag="VXB71_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2130..2627)
                     /locus_tag="VXB71_001913"
     CDS             complement(2130..2627)
                     /locus_tag="VXB71_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0451974.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2700..4061)
                     /gene="radA"
                     /locus_tag="VXB71_001914"
     CDS             complement(2700..4061)
                     /gene="radA"
                     /locus_tag="VXB71_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0451975.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4075..4590)
                     /locus_tag="VXB71_001915"
     CDS             complement(4075..4590)
                     /locus_tag="VXB71_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0451976.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4592..5035)
                     /locus_tag="VXB71_001916"
     CDS             complement(4592..5035)
                     /locus_tag="VXB71_001916"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0451977.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            5340..5489
                     /locus_tag="VXB71_001917"
     CDS             5340..5489
                     /locus_tag="VXB71_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0451978.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
BASE COUNT         1742 a         1344 c          987 g         1514 t
ORIGIN      
        1 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
       61 gtcgctgaaa cttctgatga cgtatagtca tatttcttct ctttttatta tatcacagtt
      121 ttaaatctag ctttactaga ttcaccgcta ctatccattt attcggaaaa aagacgaaaa
      181 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
      241 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
      301 tctgctcaat cttatcaatc aaacgctctt ctggcagata gatggtatcc aaaacaacca
      361 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
      421 tacagcttgc atagactgca acagcaccag cttccgcaag agcatctgcc gcatgacaaa
      481 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
      541 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
      601 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
      661 ccgggctgac aaccacatag tcagaaccaa ccataccacg ccgctcaaaa taatctgcaa
      721 ttagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
      781 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
      841 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
      901 aaggcatgac aacattgaca gactctgcac tcgcacgctt caaagcatct accataatca
      961 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaagata aagacgtgtt
     1021 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
     1081 ttgatttccc caactctatc ccaatctcct gcgccacacg ttctgccaat tctttattag
     1141 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
     1201 cgcttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
     1261 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
     1321 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa taaccataga
     1381 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
     1441 gagagttaaa caataagacc ctgtttcttg ccaaccttct gtcctttata ggctctgtaa
     1501 agcaagtaaa cacctactac agctagacct gaaaaagtcc agtgagaggc aattcctgag
     1561 atgatacgct ctaaaattcg cgaaatagta aagtcaaagc cctctggcaa atccgtacga
     1621 atataaccaa tatcctcaat catttggaat cccaaaccgg aggcaattcc aagtaaaaac
     1681 aaaaatttta attttcgcac aggaatcaaa gccaaaacaa aaacaagtgg caataatttc
     1741 aagggttctt ctaccaaagg agccacaata gcactttcaa aggcatttaa aaatggacta
     1801 tctgggaaaa gaacccccag taaatcatgt atataagtat tagcaaaact agacaaccag
     1861 cctgaaagga acatccctcc caataaagac agaatcaaaa ccttctttgg caattcccat
     1921 tttttcccaa tacggaagag aaaataaaga gccggaatca tgtaaaagag agctagaaag
     1981 atagaaactc ccattagtcc atattccgca cctgacctcg aaccgtccgt atagtagatg
     2041 gtttcatact gtaaaccaat acatagcaat aaaataaaaa taaataaaat actgcttttc
     2101 ttcatacact ttctttctaa atgaagtatt tataattcta cgactgtcat acttcctgta
     2161 tcaacattgt aaatagcacc agagataatg acatcgtctg gtattagggg agactcgata
     2221 agcagttgca tatcctcgcg tacactctct tctatatctt ggaagggcaa gaagtcctgg
     2281 tctgacacat ctacacctaa ttcctctttt aaatactcct gaaaaggttc attttcaaag
     2341 gtctgagcac cacagtctgt atggtgcaat accacaatct ctcttgtccc catttgttgc
     2401 tgggaaataa ctagcgaacg aatcatgtct tcagtcactc gaccacctgc attccgcaag
     2461 atatgagcat ccccaagtgc caagcccaga gcttgcgcaa cgtgcaaacg tgagtccata
     2521 caggtcacaa tggctactct ggttttaggt ttaagtggca gatttaactg cccatgtagg
     2581 gcaacataag cctgattggc ttgcataaac tgttcaaaat acgacacgat tccctccttg
     2641 aaaatttgat agtcaaatat ttctcctatc ttatcatttt taagagaatt tgtcacggat
     2701 tatgcaaaga cctttttcaa gacttcctga atcgttgtca cgccaatgac ctgaatttcc
     2761 ttaggcagag tgattcctgt caaggaattc tgaggtacat aaatcttagt aaagcccagt
     2821 ttagcagctt cgttgatgcg ttgctcaata cgattcacgc gccgaatctc tcctgtcaag
     2881 cccagttctc cgacaaaaca ttcctgagga ttagttggct tgtctttgta gctcgaagca
     2941 atagcaactg caacagccaa gtcaatggca ggttcatcca atttaacacc accagcagat
     3001 ttgagatagg catcctgatt ttgcaagaga agccctgccc gtttttccaa aacagccata
     3061 atcaagctag cacggttaaa atcaagtcct gtcgtagtac gcttggcatt tccaaacatg
     3121 gtcggtgtta ccaaagcctg aacctccgcc aaaatcggac gcgtcccttc catggttaca
     3181 acgatggagg aaccagtcgc cccatccaaa cgctcttcta ggaaaacttg actcggattg
     3241 agtacctcaa ccaagccgcc cgactgcatc tcaaaaatcc caatctcatt agtggaacca
     3301 aaacgatttt tgaccgctct caaaatacga aaggtgtggt gacgctcccc ttcaaagtaa
     3361 agcaccgtat ccaccatatg ctccaacata cgaggcccag ccaaggttcc ttctttggtc
     3421 acatgaccta cgataaagat ggcaatgtta ttggtcttgg ccaactgcat gagttcagcg
     3481 gtcacttcac gtacctgaga aacagacccc tgcacccctg aaatctcagg agacatgatg
     3541 gtctggatgg aatcaataat gagaaagtct ggctggatac gctccacttc tgcacgaaca
     3601 ctctgcatat tggtctctgc atagagataa aactcactat caatatcacc taagcgctct
     3661 gcacgtagtt taatctgctg ggcagactcc tccccactga catagagaac tgtccccact
     3721 tgggacaact gggttgagac ttgtaggaga agagttgatt tcccaatccc aggatcccca
     3781 ccgatgagga cgagacttcc tggtaccact ccgcctccaa gcacacggtt gaattcctcc
     3841 atctccgtct tggttcgatt gacattgatg gaagtcacct cagctagttt catgggcttg
     3901 gttttctcac ctgtcaagga cacacgcgca ttcttgacct cggcaacctc aacctcttcc
     3961 acaaaagaag accaagaccc acagttgggg caacgtccca gatatttagg ggaattatac
     4021 ccacaatttt gacatacaaa tgtcgctttt ttctttgcga tgacaaacct ctttctatat
     4081 ctctaactca cactcaatca cttggcaaaa atcaatcttc tcatttggca caaactggcg
     4141 catgagcatt cgatgagcaa caactaccac agtctgatgt tctcgatact tagacataca
     4201 ttctagaaac cgagacttca tttccgtagc tgtctcatat tgaataggac tattaggaag
     4261 caactccccc ttgttttcta aaaacagtct tctagctgtt tcaaagtttt ctattcctgt
     4321 tttatagacc tgccattcat gtaataaagg ctctactctt aaaggaagac ccgtagcaca
     4381 gaccacatac gaagccgttt ctaaagctct tgtgactgca gaagatacga ttatttcagc
     4441 tgacgagagt aaaggatttt tgctcaattt ctggacttgc tgccgtccca tctcagacaa
     4501 gggtgccaaa tctatcccaa atcctatata agaacgctcc tctaactcac ggtaatctgg
     4561 ctccccatga cgtacaaaga taatcttcat tctagtgccc tgtcgatcca aatccaccag
     4621 ttcgaacgcc atcagctgca tctccatctg caattaagaa agtagcaaaa acagcctgga
     4681 caatacgttc cccaacttca agaacaacct cttgatctgt gatattcttc atctgcgcaa
     4741 aaatatgccc ttcatttcca ggatttccat aataatcccc atcaatgacc ccaactgagt
     4801 taattaaaac caagcccttc ttacgaggat ttgaagaacg atcatagagg tagagaacct
     4861 cagtcggctg catataagcc ttaacccctg tcggaaccaa gacaatctct cctggcgcaa
     4921 caactgtacg cacagcaacc tttaagtcgt aaccagccgc atgcgctgtc tcacgcttgg
     4981 gcaataaatt ttcatctgta aaactcgaaa ccaattcaaa accacgaatt ttcataattt
     5041 tctcttttct attatcattt attctagatt attctatctt atttattcgg aaaaagcacg
     5101 aaaaaaagag cacacaacaa ttataggcga tacgataatt tacactgttt cacaatacgt
     5161 tgaaatttag agctttaaag cgagggcaaa gttgattttt tacatcgttt tacagaggtt
     5221 tacgacactt ttgccccttt tttgcccctt tgtttttcaa aaaaacttca tcaaatcgct
     5281 tgactttcac ggtttaccgt gatataatat aatcaagata aggaaaggag gtgaggaagt
     5341 tgaacaaaga agattggctt aggttactgg aaaaggcgat agataatatc cctgaaacgg
     5401 taactgctat agcaagtctg gtgactgcaa taacggtcgc aaggcaaaac aaaaagcgta
     5461 aaccgaaatc ccgtcaaaga aaaaggtgaa cgctaagagg ttggggcgaa agcccctcac
     5521 acctctattt tatcaaatga aaagaggaaa agcaatggtt agtgcaatag ctatttttat
     5581 aattgcg
//
LOCUS       DAVLAQ010000087         5240 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000087 DAVLAQ010000000
VERSION     DAVLAQ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5240
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.087"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            85..1608
                     /locus_tag="VXB71_001918"
     CDS             85..1608
                     /locus_tag="VXB71_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016648332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451979.1"
                     /translation="MFSHILGFRLETNLRKRGIDGLEKASFRFFDLNPSGQIRKIIDD
                     NAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGIILLALTIIGGLILGAMMGE
                     QEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFKSFYKAIKDYSKYAYDYSLS
                     CKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLELIMILFLSGVLFVSFMRMM
                     WYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNYNIEFENVSFAYNDKAVIEN
                     LSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSIKIGGIAISEYSDEALIKAI
                     SFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGCDLILDKFPERENTIIGSKG
                     VYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEFELQKAFKNLMKDKTVIMIA
                     HRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSLQEMFNSANEWRVSNERVL"
     gene            1592..3313
                     /locus_tag="VXB71_001919"
     CDS             1592..3313
                     /locus_tag="VXB71_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451980.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3324..3908
                     /locus_tag="VXB71_001920"
     CDS             3324..3908
                     /locus_tag="VXB71_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0451981.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            3908..4603
                     /locus_tag="VXB71_001921"
     CDS             3908..4603
                     /locus_tag="VXB71_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0451982.1"
                     /translation="MSTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4591..>5240
                     /locus_tag="VXB71_001922"
     CDS             4591..>5240
                     /locus_tag="VXB71_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0451983.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSINVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKL"
BASE COUNT         1873 a          691 c          992 g         1684 t
ORIGIN      
        1 tcaaacttat ccggtgcaga gagtatagca ttaaaatctg ttattacact aacaagtgga
       61 gcgatatttt attttgtctc aggaatgttt tcacatatct tgggatttag gcttgaaaca
      121 aatttaagaa aaaggggaat cgatggtctg gaaaaagcaa gttttaggtt ctttgactta
      181 aatccatctg gtcaaataag aaagatcata gatgataatg cagcacaaac tcatcaggtg
      241 gtagcacaca tgattcccga tagttctcag gcaataatca cacccgtact tgtacttgca
      301 cttggcttta tagtaagtat aagggttggc ataattttgc ttgctcttac tataattggt
      361 ggcttaattt taggggcaat gatgggcgag caagaattta tgaagatata ccaagaatcc
      421 ctatctaaac taagtgctga aactgttgag tacgtgagag gaatgcaagt tgtaaaaata
      481 tttaaagcaa atgtagagtc ttttaaaagc ttttataagg cgataaaaga ttactcaaag
      541 tatgcttatg attattccct atcttgtaaa aggccttatg ttttgtatca atggttattt
      601 tttggactga ttgcaatttt aattattcct atagtttatt ttatgactag cttagctagc
      661 gcaaaggtga ttttacttga gcttatcatg attttatttt tatcaggagt tctctttgtt
      721 tcattcatga gaatgatgtg gtactccatg tatatttctc aaggaaatta tgcagtagat
      781 actttagagg cgctttacga agatatgcaa aaagacaaat tagtgcatgg taatgtcaat
      841 aattttaaaa actataatat agaatttgag aatgttagct ttgcttataa tgataaagct
      901 gtcattgaaa atttatcctt taatttagaa gaaggaaagt cctacgcact tgtcggttca
      961 tctggatcag gcaaatcaac agtagcaaaa cttatatcag gtttttacaa tgttaataaa
     1021 ggaagcataa agataggcgg gatagcaata agtgaatatt ctgacgaagc cttaattaaa
     1081 gccatttcct ttgtttttca agattcaaaa ttattcaaga agagcattta tgataatgta
     1141 gctttagcta ataaagatgc gacgaaagat gacgttatga gagccttaaa attagcagga
     1201 tgcgatttaa tattagacaa attcccagaa agagaaaata caatcatagg ctcaaaaggt
     1261 gtttatttat ccggtggaga aaaacaaaga attgcaattg ctagagcaat tttaaaggat
     1321 tccaaaatta ttattatgga tgaagcatca gcatctattg acccagataa cgagtttgaa
     1381 ttgcaaaaag cttttaaaaa tcttatgaag gataaaacag ttatcatgat tgcacacagg
     1441 ctatctacaa ttaaagacct tgatgaaatt attgtcatgg atagtggaaa aattatagaa
     1501 agagggtctg acaaagaatt aatgtcaaaa gatacaaggt ataagagcct gcaagagatg
     1561 tttaacagtg cgaatgaatg gagggtttca aatgaaagag ttttataaaa aaagatttgc
     1621 tcttacagat ggaggagcaa gaaatttaag taaagcaaca ctggcttcat ttttcgttta
     1681 ttgtataaac atgcttcctg ccatattact tatgattttt gctcaggaag ttttggaaaa
     1741 tatgggcaaa agcaatggct tttatatagt attctcagtt ttgactttga tagcaatgta
     1801 tattttgctt tctatcgaat acgataaatt atataacaca acctatcaag aaagtgcaga
     1861 tttaagaata aggacagcgg agaatttatc aaaattacct ctatcttact tttctaaaca
     1921 tgacatttcc gacatttcac aaacaatcat ggctgatatt gaaggcatag agcatgcaat
     1981 gagccactca ataccaaagg tgggcggcat ggtactgttt ttcccattaa tatctgtaat
     2041 gatgctagcg ggcaatgtca agatgggttt agctgtaatt attccatcta ttttaagctt
     2101 tatatttata cctttatcta aaaaatatca ggttaatgga cagaatagat attatgatgt
     2161 cttaagaaaa aactcagaaa gctttcaaga aaatatcgaa atgcaaatgg agattaaagc
     2221 atataattta tcgaaggata ttaaagatga cttatataaa aaaatggaag atagtgagag
     2281 agtacactta aaggcagaag taactacaat tttaactttg tctatatctt caatatttag
     2341 ctttatatct cttgctgttg tgatatttgt cggcgtaaat ctaattatta ataaagagat
     2401 aaattctctc taccttatag gatatttact agctgctatg aagataaaag actctttaga
     2461 tgcatctaaa gagggcttga tggaaatatt ttatttatcg cccaaaatag aaagattaaa
     2521 agaaattcaa aatcaagatt tacaagaagg cgatgactat agcttaaaaa aatttgatat
     2581 tgatctaaaa gatgttgagt ttgcctacaa taaagacgca aaagttttaa atggtgtaag
     2641 ttttaaagct aagcagggag aggtcactgc tttggtaggt gcaagtggct gcggtaaaac
     2701 aactatcttg aaacttatat caagacttta tgattatgac aagggacaaa tcttaatcga
     2761 tggcaaagat ataaaagaaa tatcaacaga atctcttttt gataaggtct ctatagtttt
     2821 ccaagatgtg gttctcttta atcaaagcat tatggaaaat attagaatcg gaaagcaaga
     2881 tgcaagtgac gaagaggtta aaagagcagc aaaacttgca aattgcacag attttataga
     2941 aaaaatggat aaaggtttcg atacagttat tggtgagaac ggagctgagc tatcaggagg
     3001 agaaagacaa agattatcaa tagccagagc cttcttaaaa gatgcgccga tattgatctt
     3061 agatgagata acagcaagcc ttgatgttaa caacgagaaa aagattcaag agtctttaaa
     3121 taatttagtt aaagataaaa ctgttgtaat catttcacat agaatgaaat ccatagaaaa
     3181 tgcagacaag atagtagttc ttcaaaacgg aagagtagaa agcgaaggta agcatgaaga
     3241 gcttttacaa aaatcaaaaa tttacaaaaa tttaatagaa aagacaaaaa tggcagaaga
     3301 atttatttat taggaggact acaatggata ataaaaaatt aaaagtaaaa gatttagtaa
     3361 gtatcggtgt ttttggcgta atttattttg ccttcatgtt tggagttggt atgatgggct
     3421 tgattccaat attgttctta atatacccga cagtattagc catagttgca ggaactgttg
     3481 ttatgttatt tatggctaag gttcaaaagc catgggcact atttatattt ggtatgatat
     3541 caccacttgt gatgtttgca gctggtcata cctacgtagt tgtggtttta tcacttatag
     3601 taatgataat agcagaatta attagaaaga ttggtaatta taattcattt aaatacaata
     3661 tgctttctta tgcaatcttc agcacatgga tatgtagctc tttaatgcaa atgcttttag
     3721 caaaagaaaa atatatggag tggtctttga tgacgatggg aaaagattat gttgatgtat
     3781 tagaaaagtt aataacttat cctcacatgg ctttagtagc cttaggtgct ttcttaggag
     3841 gaattcttgg agcatatata ggcaaggctc tattgaaaaa acactttgaa aaagcaggca
     3901 ttgtataatg tctacttttt cttcaaatgc tccctttaat cccaatccga tctctaagat
     3961 attagtcgta tttatcacag gcttaactgt tatgcatagc ataaacatcc gttttgagct
     4021 ggcaattgtt tgtcttattg gtattttgct ttatttgaat ggatacaaaa aaacactttt
     4081 caaatggatt atattgtgtg ggatacttta ctccttgcct aattttatgg tgttatctga
     4141 attaaaccct atagttaaga tgtttttgag tatacctatt gttattagaa tgtttatttt
     4201 accatttatg gcagcaagct ttatgataaa gacctcggat gtaggcgcaa taatttcatc
     4261 gatggataag cttaagattt caaagaatgt atccatacct attgcggtta tgtttagatt
     4321 cttcccatct tttaaggagg agaagaaaaa catcaaaatg gctatgagag taagagggat
     4381 aagttttaaa aacccagtca aatatcttga atatgtttct atgccactac tcattatatc
     4441 atctaatata tcagatgaca ttgcaaaagc ggcagaaaca aaggcaatag aaaatccaat
     4501 tgccaagacc agatacattc gcgtaaagat acagctaatt gattttgttt atgttttagc
     4561 ggttgctgga cttattgtgg gaggcttaat atggttgaaa taaaaaattt aagtcttgat
     4621 tatggtgaag agcatatatt agatgatata tcactatcca tagccgaggg agagtgcgtg
     4681 ctatttacag gaaaaagtgg aaatggtaag tcatctttaa taaattcaat caatggacta
     4741 gctgtaaggt atgataacgc aaagacaaag ggcgaaataa ttattgatgg taagaatata
     4801 aaaaatttgg aactttatca aatctcaatg cttgtttcaa ctgtttttca aaatcctaag
     4861 acatattttt ttaatgtcaa tacgacatta gaattattat tttatttgga aaatatcggt
     4921 cttgcaagag aagagatgga caggcgtttg aaggatatgc ttaagatatt cccgataaaa
     4981 aatcttttga acagaaatat atttaatcta tccggcggtg aaaaacaaat tctttgcatt
     5041 gcagcttctt atatagcagg tacaaagatt atagttatgg atgagccttc atcgaattta
     5101 gatattaaaa gcataaatgt tttggcaaag atgctaaaga tattaaaaga gaaaggcata
     5161 agcataattg ttgcagagca tagaatttat tatttgatgg acatagttga ccgtgtattt
     5221 ttaatagata aaggaaagct
//
LOCUS       DAVLAQ010000088         5055 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000088 DAVLAQ010000000
VERSION     DAVLAQ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.088"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            185..1730
                     /locus_tag="VXB71_001923"
     rRNA            185..1730
                     /locus_tag="VXB71_001923"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1782..1854
                     /locus_tag="VXB71_001924"
     tRNA            1782..1854
                     /locus_tag="VXB71_001924"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1815..1817,aa:Ala,seq:tgc)
     gene            1979..4880
                     /locus_tag="VXB71_001925"
     rRNA            1979..4880
                     /locus_tag="VXB71_001925"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4957..>5055
                     /gene="rrf"
                     /locus_tag="VXB71_001926"
     rRNA            4957..>5055
                     /gene="rrf"
                     /locus_tag="VXB71_001926"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1425 a         1024 c         1487 g         1119 t
ORIGIN      
        1 gttgacaagt gaaagtggct gtgatatact aatatagttg tcgcttgaga gaagcaagtg
       61 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
      121 gtagtactga acaatgaaaa aacaataaat ctgtcagtga cagaaatgag taagaactca
      181 aacttttaat gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
      241 gcaagtagaa cgctgaagga ggagcttgct tctctggatg agttgcgaac gggtgagtaa
      301 cgcgtaggta acctgcctgg tagcggggga taactattgg aaacgatagc taataccgca
      361 taagagtaga tgttgcatga catttgctta aaaggtgcac ttgcatcact accagatgga
      421 cctgcgttgt attagctagt tggtggggta agggctcacc aaggcgacga tacatagccg
      481 acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc tacgggaggc
      541 agcagtaggg aatcttcggc aatggacgga agtctgaccg agcaacgccg cgtgagtgaa
      601 gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa cgagtgtgag agtggaaagt
      661 tcacactgtg acggtatctt accagaaagg gacggctaac tacgtgccag cagccgcggt
      721 aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg caggcggtta
      781 gataagtctg aagttaaagg ctgtggctta accatagtag gctttggaaa ctgtttaact
      841 tgagtgcaag aggggagagt ggaattccat gtgtagcggt gaaatgcgta gatatatgga
      901 ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg acgctgaggc tcgaaagcgt
      961 ggggagcaaa caggattaga taccctggta gtccacgctg taaacgatga gtgctaggtg
     1021 ttagaccctt tccggggttt agtgccgtag ctaacgcatt aagcactccg cctggggagt
     1081 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagcatg
     1141 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccct ctgaccgctc
     1201 tagagataga gttttccttc gggacagagg tgacaggtgg tgcatggttg tcgtcagctc
     1261 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt tagttgccat
     1321 catttagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg tggggatgac
     1381 gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg ctggtacaac
     1441 gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc agtctcagtt cggattgtag
     1501 gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc acgccgcggt
     1561 gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt gtaacacccg
     1621 aagtcggtga ggtaaccgta aggagccagc cgcctaaggt gggatagatg attggggtga
     1681 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggataa
     1741 ggaactgcgc attggtcttg tttagtcttg agaggtcttg tggggcctta gctcagctgg
     1801 gagagcgcct gctttgcacg caggaggtca gcggttcgat cccgctaggc tccattggtg
     1861 agagatcacc aagtaatgca cattgaaaat tgaatatcta tatcaaatag taacaagaaa
     1921 ataaaccgaa aacgctgtag tattaataag agtttatgac tgaaaggtca gaaaataagg
     1981 ttaagttaat aagggcgcac ggtggatgcc ttggcactag gagccgacga aggacgtgac
     2041 aaacgacgat atgccttggg tagctgtaag taagcgatga tccagggatt tccgaatggg
     2101 ggaacccaac aggtaatacc tgttacctac atctgttaag gatgtgagga ggaagacgca
     2161 gtgaactgaa acatctaagt agctgcagga agagaaagca aaagcgattg ccttagtagc
     2221 ggcgagcgaa acggcagaag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     2281 aatgtggact caaagattat agaagaatga tttgggaaga tcagccaaag agagtaatag
     2341 cctcgtattt aaaatagtct ttgtacttag cagtatcctg agtacggcgg gacacgtgaa
     2401 atcccgtcgg aatctgggag gaccatctcc caaccctaaa tactccctag tgaccgatag
     2461 tgaaccagta ccgtgaggga aaggtgaaaa gcaccccggg aggggagtga aatagaacct
     2521 gaaaccgtgt gcctacaaca agttcgagcc cgttaatggg tgagagcgtg ccttttgtag
     2581 aatgaaccgg cgagttacgt tatgatgcga ggttaagttg aagagacgga gccgtaggga
     2641 aaccgagtct gaatagggcg ccttagtatc atgacgtaga cccgaaacca tgtgacctac
     2701 ccatgagcag gttgaaggtg cggtaagacg cactggagga ccgaaccagg gcacgttgaa
     2761 aagtgcttgg atgacttgtg ggtagcggag aaattccaaa cgaacttgga gatagctggt
     2821 tctctccgaa atagctttag ggctagcgtc gacattagag attcttggag gtagagcact
     2881 gtttgggtga ggggtccatc ccggattacc aatctcagat aaactccgaa tgccaatgaa
     2941 ttatggtcgg cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag
     3001 accaccagct aaggtcccaa aataattgtt aagtggaaaa ggatgtgggg ttgcacagac
     3061 aactaggatg ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt
     3121 cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacaa tttaccgaag ctgtggatac
     3181 ctttataggt atggtaggag agcgttctat gtgtgatgaa ggtataccgt gaggagtgct
     3241 ggaacgcata gaagtgagaa tgccggtatg agtagcgaaa gacaggtgag aatcctgtcc
     3301 accgtaagac taaggtttcc aggggaaggc tcgtccgccc tgggttagtc gggacctaag
     3361 gagagaccga aaggtgtatc cgatggacaa caggttgata ttcctgtact agagtatgta
     3421 gtgatggagg gacgcagtag gctaactaaa gcagacgatt ggaagagtct gtctaagcag
     3481 tgaggtgtga attgagtcaa atgcttaatt ctataacatt gagctgtgat ggggagcgaa
     3541 gtttagtagc gaagttagtg acgtcacact gccaagaaaa gcttctagcg tttaaacata
     3601 ctctacccgt accgcaaacc gacacaggta gtcgaggcga gtagcctcag gtgagcgaga
     3661 gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac
     3721 ttaaagtcag ccgcagtgaa taggcccaag caactgttta tcaaaaacac agctctctgc
     3781 taaatcgtaa gatgatgtat agggggtgac gcctgcccgg tgctggaagg ttaagaggag
     3841 tgcttagcgt aagcgaaggt atgaattgaa gccccagtaa acggcggccg taactataac
     3901 ggtcctaagg tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaatg
     3961 atttgggcac tgtctcaacg agagactcgg tgaaatttta gtacctgtga agatgcaggt
     4021 tacccgcgac aggacggaaa gaccccatgg agctttactg cagtttgata ttgagtgtct
     4081 gtaccacatg tacaggatag gtaggagtct aagagatcgg gacgccagtt tcgaaggaga
     4141 cgctgttggg atactaccct tgtgttatgg ccactctaac ccagataggt gatccctatc
     4201 ggagacagtg tctgacgggc agtttgactg gggcggtcgc ctcctaaaag gtaacggagg
     4261 cgcccaaagg ttccctcaga atggttggaa atcattcgca gagtgtaaag gtataaggga
     4321 gcttgactgc gagagctaca actcgagcag ggacgaaagt cgggcttagt gatccggtgg
     4381 ttccgtatgg aagggccatc gctcaacgga taaaagctac cctggggata acaggcttat
     4441 ctcccccaag agttcacatc gacggggagg tttggcacct cgatgtcggc tcgtcgcatc
     4501 ctggggctgt agtcggtccc aagggttggg ctgttcgccc attaaagcgg cacgcgagct
     4561 gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc gcgggcgtag gaaatttgag
     4621 aggatctgct cctagtacga gaggaccaga gtggacttac cgctggtgta ccagttgtct
     4681 tgccaaaggc atcgctgggt agctatgtag ggaagggata aacgctgaaa gcatctaagt
     4741 gtgaaaccca cctcaagatg agatttccca tgattatata tcagtaagag ccctgagaga
     4801 tgatcaggta gataggttag aagtggaagt gtggcgacac atgtagcgga ctaatactaa
     4861 tagctcgagg acttatccaa agtaactgag aatatgaaag cgaacggttt tcttaagttg
     4921 aatagatatt caattttgag taggtattac tcagagttaa gtgacgatag cctaggagat
     4981 acacctgtac ccatgccgaa cacagaagtt aagccctaga acgccggaag tagttggggg
     5041 ttgccccctg tgaga
//
LOCUS       DAVLAQ010000089         4999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000089 DAVLAQ010000000
VERSION     DAVLAQ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.089"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..607
                     /locus_tag="VXB71_001927"
     CDS             <1..607
                     /locus_tag="VXB71_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV0451984.1"
                     /translation="SDTLPDFMVHEVESIWNEYETFNNIRVLDVGADLAYFKHLKLLS
                     NELGEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLLSDEGSISAKEFIYIVENQ
                     EIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRYNVDGPLV
                     LARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYGS"
     gene            597..917
                     /locus_tag="VXB71_001928"
     CDS             597..917
                     /locus_tag="VXB71_001928"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV0451985.1"
                     /translation="MEANKYKIGIIGSHDIILPFSMIGFDIFSAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            980..2755
                     /locus_tag="VXB71_001929"
     CDS             980..2755
                     /locus_tag="VXB71_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV0451986.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            2756..4141
                     /locus_tag="VXB71_001930"
     CDS             2756..4141
                     /locus_tag="VXB71_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV0451987.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            4164..4775
                     /locus_tag="VXB71_001931"
     CDS             4164..4775
                     /locus_tag="VXB71_001931"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV0451988.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         1637 a          710 c         1052 g         1600 t
ORIGIN      
        1 ttcagataca cttcctgatt ttatggttca tgaagtagaa tcaatttgga atgagtatga
       61 aacttttaat aatattcgtg tacttgatgt cggagctgat ctagcatatt ttaaacatct
      121 gaaactttta tctaatgagt taggtgaggt gctgtctcag gttattgttg caatgattga
      181 cttttataat attattactg taaaacgtgg tttatctcaa aataagagtc atggggatat
      241 tttacaatta ctttcagatg aaggaagtat ttctgctaaa gaatttatat acattgtaga
      301 aaatcaagaa atatttgtgt ggttcaataa aataaatcca agcttagatt caatcttttc
      361 aacttacgaa ttgaagatgc aggacgcaac aatttcatct tctgagttag aatttttatg
      421 tgatttacta ttgtataaaa ctttagatca aggaaggtat aatgtagatg ggccgttagt
      481 tcttgctaga tatttattgg gatgtgagtt tgaagtaaag aatcttagaa tgatcatatc
      541 agctcttcaa aatacaattc cttttgaatc aataaaagaa aggatacgcc cgcattatgg
      601 aagctaataa gtataaaatt ggcataattg gtagccatga tattatttta ccctttagca
      661 tgattgggtt tgatatattt tctgcctatc aagaacaaga agctataaat actctaagaa
      721 aattagctca atctgattat ggtgtcattt atatcactga agacattgct tcaatgatat
      781 tagatacaat tcgccattat gattctcaag ttgtgcctgc tattatttta ttaccgactc
      841 ataaacaagg tttaaattta ggattaaaac gtatagagga taatgtagag aaagcagtag
      901 gacacaatat tttataataa tgtacaaaat tgtctgtaat attattctat aatttttgga
      961 cttagtaagg agaataactt tgactcaagg gaagattata aaagtatcgg gacctctagt
     1021 tattgcatca ggtatgcagg aggctaatat tcaagatatt tgccgtgtag gtaagctagg
     1081 gttaatcggt gaaattattg aaatgagaag agatcaggca tctatccaag tctatgaaga
     1141 aacatctggt cttggtccgg gagaacctgt tgttacaact ggagaacctc tctcggttga
     1201 attagggcca ggattgattt ctcaaatgtt tgatggcata caacgcccat tagatcgatt
     1261 taaattggct actcataatg attttctagt tcgtggggta gaagttccaa gtttggatag
     1321 agatattaag tggcattttg attccactat agcaattggt caaaaagtga gtacgggtga
     1381 tattcttgga actgtcaagg aaaccgaggt agttaatcat aaaattatgg ttccttatgg
     1441 agtatctgga gaagtcgttt ctattgcatc tggcgatttt acaattgatg aagttgtata
     1501 tgaaataaaa aaattggacg gtagtttcta taaaggaacg cttatgcaaa aatggcctgt
     1561 ccgcaaggcg cgtcctgttt ctaaacgttt aattccagaa gaaccattaa tcacaggtca
     1621 acgagttatt gatgcattct ttccagtaac caaaggggga gctgcagcag ttcctggacc
     1681 gtttggagca ggaaagacag ttgtacaaca ccaagtagct aaatttgcca atgttgatat
     1741 tgttatttat gtcggttgtg gagaacgtgg aaatgaaatg acggatgtac tgaatgagtt
     1801 tcctgagttg attgacccta ataccggaca atcaattatg caacggacag ttctgattgc
     1861 taatacttca aatatgcctg ttgctgctcg tgaggcttca atttatacag gaattaccat
     1921 ggctgagtat tttcgtgata tgggctactc tgtcgccatt atggctgatt caacttcacg
     1981 ttgggcagaa gcgctacgtg aaatgtcagg acgtctagaa gaaatgcctg gtgatgaggg
     2041 ttatcctgct tatctgggaa gtcgtatcgc tgaatattat gaaagagcag gacgttctca
     2101 ggttctaggg cttccagaac gtgaaggaac gattactgct attggagctg tatcgccacc
     2161 tggtggagat atttcagaac cagttactca aaacacttta cggattgtga aagttttttg
     2221 ggggcttgat gctccgttgg cacagcgacg tcattttcct gcaattaact ggcttacatc
     2281 ttattcacta tataaagaca gtgtgggcac ttatatagat ggtaaagaga agacagattg
     2341 gaatagtaaa ataactcgtg cgatgaacta cttacaacgg gaatctagtt tagaggaaat
     2401 tgttcgtctt gttggaattg attctctgtc tgataatgaa cgactaacga tggaaattgc
     2461 taaacaaatt cgagaagatt atttgcaaca gaacgctttt gattcggtag atacattcac
     2521 ttcgtttgca aaacaagaag caatgctaag taatattctc acttttgctg atcaggcaaa
     2581 tcatgcttta gagttgggtt cttactttac agagattatg gaaggtaccg tggcagttcg
     2641 agaccgtatg gcgagaagta aatatgtttc agaagataga ttagatgaaa tcaaaattat
     2701 atcaaatgag attacacatc aaattcattt gatattagaa acaggaggtc tataaatgag
     2761 tgttataaaa gaatacagaa ctgctagtga agttgttggg cctcttatga ttgttgaaca
     2821 agtaaataat gtgtcttaca atgagttagt tgaaattcaa cttcataatg gagaaattcg
     2881 tcgtggacaa gttttagaga tccacgaaga taaagcaatg gttcagcttt ttgaaggatc
     2941 tagtggaata aatttagaaa agtctaaaat tcgttttgct ggtcatgcat tagaattggc
     3001 tgtatctgag gatatggttg gtcgtatttt taatgggatg ggaaaaccaa ttgatggtgg
     3061 accagattta attccagaga aatatttaga tattgatggt caagctatta atcctgtatc
     3121 tagagattat ccagatgaat ttattcagac agggatctcc tctattgatc atttgaatac
     3181 tcttgtacgt ggtcaaaaat taccagtatt ttcaggttcg ggcttacctc ataatgaatt
     3241 agctgctcag atagcaagac aagcgactgt tttaaattct gatgaaaatt ttgcggttgt
     3301 atttgcagca atgggtatta cttttgaaga agctgagttt tttatggaag aactcagaaa
     3361 aacaggagcg atcgatcgtt cggttttatt tatgaacttg gcaaatgatc ctgcaattga
     3421 gcgtattgca actccccgca ttgctttaac tgcggcagag tatctagctt ttgaaaaaga
     3481 tatgcacgtt ctagttatca tgacggatat gactaactat tgtgaagcgt tacgtgaagt
     3541 ctcggcagct cgccgtgaag ttccagggag acgaggctat ccgggatatt tatatacaaa
     3601 tttatcaact ctatacgaaa gggctggtcg cttagttggt aaaaaaggtt cggtgacaca
     3661 gattcctatt ttaacaatgc cagaagatga cataacacat ccaattcctg atttaactgg
     3721 atacattact gaagggcaaa ttattttgtc gcatgagttg tataatcaag gttatcgtcc
     3781 accaatcaat gttttacctt ctctctctcg attaaaagat aagggatctg gagaaggtaa
     3841 aactcgtgga gatcatgctc caactatgaa tcaactgttt gcagcctatg cccaagggaa
     3901 aaaggttgaa gagttagcag tagtattagg agaatcggct ttatctgatg tagataaatt
     3961 gtatgtgagg tttacaaagc gttttgaaga agagtacata aaccaaggat tttataaaaa
     4021 tcgaaatata gaagatacgt tgaatcttgg gtgggaatta ctatcaattc ttcctagaac
     4081 agagttaaaa cgtatcaaag atgatttgct tgataaatac ttacctttgg tagaagttta
     4141 atccggaaat ggagtgatta tctatggtac gtttgaatgt aaaaccaact cgtatggaat
     4201 tgaataactt aaaggaacgt ttgacaacag ctgaacgtgg acataagtta ttaaaggata
     4261 aaagagatga attgatgagg cgatttattt ctttgattcg tgagaataat caacttcgga
     4321 aagaagtgga aagttatcta attgataatc taaaatcctt tgcagttgct aaatcattaa
     4381 agaattctca aatggtggag gaattatttt caattccatc gaaagaaatt gaattatttg
     4441 ttgagaaaga aaatatcatg agtgtaacag ttcctagaat gcatatgaat attacttctc
     4501 aaaatgagaa cagtgaatac agctatttat cttctaatag tgaaatggat gatgtatttg
     4561 ctacaatgaa tagtttaatt tataaattac taagactggc agaagttgaa aaaacgtgtc
     4621 agttaatggc tgatgaaata gaaaaaacac gtagacgtgt aaatggttta gaatactcga
     4681 ttattccaaa cttgtcggaa actattcatt atatagaatt gaaactagag gaggcagaaa
     4741 gagccaattt agttcgtatt atgaaagtga agtagatcct ttatttagat tattaattag
     4801 atgaacaaat atcagcttgg ataaggcttt aagcctttct aagctttttt tattgacagt
     4861 atcaggatat ctttttcaaa attttggttt gttagataat gaaaatgttt ctactaatct
     4921 agatttagga ttagtaaatc gtaaatgtaa ttatatagaa agtaagcgcg tcataacaag
     4981 gtatctatca ttcatggag
//
LOCUS       DAVLAQ010000090         4760 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000090 DAVLAQ010000000
VERSION     DAVLAQ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.090"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(357..1085)
                     /locus_tag="VXB71_001932"
     CDS             complement(357..1085)
                     /locus_tag="VXB71_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0451989.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1243..2652
                     /locus_tag="VXB71_001933"
     CDS             1243..2652
                     /locus_tag="VXB71_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0451990.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2670..3965
                     /locus_tag="VXB71_001934"
     CDS             2670..3965
                     /locus_tag="VXB71_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0451991.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3970..4278
                     /locus_tag="VXB71_001935"
     CDS             3970..4278
                     /locus_tag="VXB71_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0451992.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4275..4583
                     /locus_tag="VXB71_001936"
     CDS             4275..4583
                     /locus_tag="VXB71_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0451993.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1610 a          812 c          874 g         1464 t
ORIGIN      
        1 gagattgaaa ttcatttcta gcaatttgtt agaagtcaca gtctactatt ctaacctcag
       61 tatactatat gtgttacaag aaaagactca aaaacttctc gtcagtgtaa gaatatttga
      121 aacactattt aaaactaaat aactataaga agtagatcag gtgaacaatt tcagtaccta
      181 ctctataagc tatacgaaga tatttttcaa catgatggat aaaacgatca ctcttttaaa
      241 gccatcttat ttagaaaaga gaaaccattt aagcatagat gggaccttct tgccctgttt
      301 taaatttttc ttaaactaga gtctgtaaaa gattggcttc attttcacat tttctcctag
      361 gaggaatgtc gtaatgcaaa agaattaaat tcaaataaat catagcgatg acgactaatc
      421 gagtactcaa acggagttcc gttatccaaa taagccactt gttctacttc aaataccggt
      481 tccgttggaa ggagctgcaa gtaatgttgc tcattttctg aactagaaga agctcgtaag
      541 atttttgtag cactggcaat atgcaatcct aactttcctt caatgtaatt gtaaatcgat
      601 ttttgtaaaa tatcttcagt aatacctgga ataacatcgg tactcatata agtttgttcc
      661 agaacataag gtttaccgtc aataatacgc aggcggtaaa tattataaac tggactctgc
      721 aaagcgacct gtagtttttc tgctaaaaat tcatttgcaa attctaattt gaagtgaata
      781 atcctcgagt caattgtaga atgagcatct tcagatattt ttgtcagtcc ccggatatct
      841 ctttctggaa cgattaattt tctttttgag ctgccacgag agagaacaaa ggttccctgc
      901 ccacgttttc taaaaattaa gccctcagaa actaacaagt ctaaagcttt tttgatcgtc
      961 attcgactac aggcaaactg tttagctaat gtcatttcat caggtaattg ttcgttcatg
     1021 gtatatttat tacaaagaat cttttcacga atctcattgt aaataaataa atattttgta
     1081 ctcatttaat ctggttctct ctataatatt ctaatagtag tataacaaag ttcaagaaat
     1141 gaggcaaaca caagatatgt atcaacaatt tttaaaaatg tctagacaaa ttttaaaatt
     1201 atgctatact ttatgtatag aataatagaa aggaggttga gcatgaaaaa aaagttagta
     1261 tttcctaatc tgttttggtg gggagcagct tctagcggac ctcagacaga aggtcaatat
     1321 ggaaaagtac atgaaaatgt gatggactac tggttcaaaa cgcatccaga agattttttc
     1381 gataatgtcg gacctcttgt agccagtaac ttttttcata cttacaccga agatttccac
     1441 ttgatgaagg aaattggagt taattctttc cgcacttcca tccaatggag tcgactcatc
     1501 aagaatttag agacaggtga gcctgatcca aaaggtattg ctttctacaa tgccatcatt
     1561 gaagaagcta aaaagaacca gatggatctt gtgatgaatt tacatcattt tgatttacca
     1621 gtggaacttc ttcaaaaata cggtggttgg gaaagcaaac atgtagtgga gttattcgtg
     1681 aagtttgcca agactgcttt cacatgcttt ggagataagg ttcattactg gacaactttc
     1741 aatgagccaa tggtcattcc agaagcagga tacttatatg ctttccatta tccaaatcta
     1801 aaaggaaagg gaaaagaggc cgtacaagtc atctataatc taaaccttgc tagtgcaaaa
     1861 gtgattcaac tatatcgctc attagaactt gatggaaaga ttgggattat tttaaacttg
     1921 acacctgctt atccaagaag taattctcca gaagacttag aagcaagtcg atttacagat
     1981 gacttcttta acaaagtctt cttgaatcca gctgttaaag gaactttccc agaaagattg
     2041 gtaaaacagc tagagagaga tggcgtgtta tggagtcata ccgaaaaaga gcttcaactg
     2101 atgaaatcaa atacggttga ttttcttgga gtaaactact accatccaaa acgtgttcaa
     2161 gcacaagcaa atcctgagga atatcagacg ccctggatgc cagaccaata cttcaaagag
     2221 tatgaatggc cggagcgtcg catgaatcca tatcgtggtt gggaaatttt tccgaaatcc
     2281 atttatgata ttgctatgat tgtgaaggaa gaatatggta atatcccatg gtttatcagt
     2341 gaaaacggaa tgggtgttga aaacgaagca cggtttatcg atgaaaatgg agttatcgat
     2401 gacgtgtatc gtattgaatt ttatgaagaa catttaagat ggctacataa agccattgaa
     2461 gagggaagtc actgttttgg ataccacgct tggaccgcat ttgattgctg gtcttggaat
     2521 aatgcatata agaatcgtta cggatttatc tccgttgatt tagaaacgca aaagagaacc
     2581 atcaagagct caggaagatg gtatcgcaaa gtaagtgaca ataacggttt tgaagtagaa
     2641 attgaggagt aaagagagga gatattcata tgaaaaactc aaaatttata gaccaatttg
     2701 ccacctttgc tggtaaacta gggaaccaaa ttcatttaaa aaccctaaga gatgcattcg
     2761 taacagtaat gccattatat attttggcag gtttaatcgt tcttttgaac aacacggtat
     2821 ttaagtggat tttccaaggg gatacattaa caagattcca atattgggga ataacaattg
     2881 caaacggtac tttaagtatt tcaggtatga ttattgctgt aatggttggt tatttcttag
     2941 ctaaaaacag agatttcgaa aacccgttag cagcatcaat gctatcatta gtttctttaa
     3001 ttgtgatgat gccaaataca gtttctgtag ttcctgacgg agcaaaagat gctgtaaaca
     3061 tttcaggtgt tctttcattc aacaacacag gtacaggcgc aatgttcgcc ggggttatcg
     3121 tagcgattat tgcaacagaa ttattcattg aattatcaaa tgttaaagct ttacaaatga
     3181 accttggtga aaatattcca ccagctgtta atagatcatt tagcgtatta cttccagtca
     3241 tgaccgtcat ctccttattt ggggttgttt cagcattatt attcaatata actggaatga
     3301 acttaatctc aatcattaca atctttattc aagaaccaat tcgtcatatt ggtacaagct
     3361 taatcggggt cattattatt tactctttag gaaatatgtt atggctattt ggtattcacc
     3421 aagcagttat ttacagtgcc atcctagaac cattactatt aattaacatt actgaaaaca
     3481 tcactgcagc aaataatgga caagccattc cacacatcat caacctatca caaatacaaa
     3541 cattcgcttt aatgggtggt agtggatcta cattatgttt attaatagca acattcttag
     3601 tgagtcgcaa tgctgtctct aaaaacgtgg ctaaattatc ttttggacct ggtatcttca
     3661 atatcaatga accagtatta ttcggttacc caatcgttta taacatttca ttagctattc
     3721 catttatcac agttccagtc cttggtattt taatcagcta cttagcaaca gttacaggat
     3781 tcatgagtcc tgcatttata caagttcctt ggactacacc agtattctta aatgcatggt
     3841 tagcaacagc aggggacgtg agagcagttc tagttcaatt catcatcttt gcacttggag
     3901 ttcttctata cattccattt atcaaagtta atgacaaagt tgttgaacaa gaaatggaag
     3961 gttaagatta tgaaacaaat tttattagta tgtaatgcgg gaatgtcgac aagtatgctt
     4021 gttaaaaaaa tgcaacaaag tgcgactgaa cgtgggattg aaatctctat ccaagcaaaa
     4081 tcaatgacag aagctaaaaa gaatatccat gaagcagatg tcattctaat tgggccacaa
     4141 attcgttatg agttacttgc tgtgaaagaa attgcaggaa atatccctgt agataccatt
     4201 gatatgcggg attacggaat gatgaatgga gcaaaagttc tggaacaagc acttgcatgg
     4261 ataggagaaa taagatgaca gaagaaatgg aatatatctg ttttcagctc attgccaata
     4321 gtggagcagc caaatcatcc tttattgaag ccatccaact agctaaggca ggaaatttaa
     4381 aagaagcgaa aattaaagtt gaagaagcgg aagactcctt agtagaagcg cacaagattc
     4441 actctaatct catacaaaaa gaagctactg gagaaaaaat aggattctcc ttgctattta
     4501 tgcatgcaga agaccaaatg gcttcaacag agattattca gttgctatct aaagaattca
     4561 tcgatctcta tcaaaataaa taggaacact gtcattccca tctgtcttta ttaatgacga
     4621 ctacattgta ggaacctcca aaagttggac aaaatgattg aaaggattgg atcctgcatt
     4681 acacaagatc caatcctttt cttttactct agtttttata atatgttgaa tctagaatag
     4741 tccactgtag tttctaaaaa
//
LOCUS       DAVLAQ010000091         4673 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000091 DAVLAQ010000000
VERSION     DAVLAQ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.091"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(188..259)
                     /locus_tag="VXB71_001937"
     tRNA            complement(188..259)
                     /locus_tag="VXB71_001937"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(224..226),aa:Arg,seq:cct)
     gene            complement(301..648)
                     /gene="rplS"
                     /locus_tag="VXB71_001938"
     CDS             complement(301..648)
                     /gene="rplS"
                     /locus_tag="VXB71_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0451994.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(767..1096)
                     /gene="crcB"
                     /locus_tag="VXB71_001939"
     CDS             complement(767..1096)
                     /gene="crcB"
                     /locus_tag="VXB71_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0451995.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1090..1464)
                     /gene="crcB"
                     /locus_tag="VXB71_001940"
     CDS             complement(1090..1464)
                     /gene="crcB"
                     /locus_tag="VXB71_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0451996.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(1461..1727)
                     /locus_tag="VXB71_001941"
     CDS             complement(1461..1727)
                     /locus_tag="VXB71_001941"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0451997.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(1843..2286)
                     /locus_tag="VXB71_001942"
     CDS             complement(1843..2286)
                     /locus_tag="VXB71_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0451998.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2390..3325
                     /locus_tag="VXB71_001943"
     CDS             2390..3325
                     /locus_tag="VXB71_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0451999.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3379..3663
                     /locus_tag="VXB71_001944"
     CDS             3379..3663
                     /locus_tag="VXB71_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0452000.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3720..3938)
                     /locus_tag="VXB71_001945"
     CDS             complement(3720..3938)
                     /locus_tag="VXB71_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452001.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(3935..4673)
                     /locus_tag="VXB71_001946"
                     /pseudo
     CDS             complement(3935..4673)
                     /locus_tag="VXB71_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1449 a         1012 c          832 g         1380 t
ORIGIN      
        1 agaacttgac gattttgaat aaattgacta tacaaacatt tatatactcg atatagtctc
       61 aattttatct gatgattgcc caaatttttc aataataaaa cgcataatat tatggagaca
      121 atcccctata ttatgcgttc ttttaatatc aaagactttt tgacaaactt cttcgatatc
      181 taattactgc cccctgcagg aatcgaacct gcaactactc cttaggaggg agttgttata
      241 tccattgaac taagggagct agataaaaac tctgctgaaa agcagagttt tttagtcgaa
      301 ttaacgacgg atttctttga tacgagctgc cttaccttga agagcacgca agtagtacaa
      361 tttcgcacga cgtactttac cgtaacgaac aacttcgatt ttttcaacac gtggagtgtg
      421 gattgggaag atacgctcaa cacctacacc gttagagatt ttacgaactg tgtagttttc
      481 tgagattcca gcacctttac gtgcgataac aacaccttca aaaatctgga tacgttcacg
      541 gttaccttcg acaactttcg catgtacacg aacagtgtca ccaggacgga atgatgggat
      601 atctgtacga agttgacctt cagtcaagct ttggattaat ggattcattt tattctccta
      661 tctttgtcaa tcttgaggaa tcttcctcag cggataaact gtatttttgt gcgtccatta
      721 cacacaagat atagtttacc aaatttctaa aaaaaagtaa agaaatttat agcaaaattc
      781 ctaaaaaaat cgcaaccaaa ccacctatgt aagtcaaagt caggtaagaa taaaagacct
      841 tcttatcact tagcagtctt tgaagttcgt cattcaaggt cgaaaaagtt gttaaaccgc
      901 cacaaaatcc tgttgctaga atagcatata cttccttaga ctctacatga ttgtagaata
      961 ctccaattaa aaaacaacct aaaagattag ctatgagcgt tccgagtggc aatttagaag
     1021 cttgattata gcgagaaaag aaataccgta cgagtgctcc caagccacag gcgattgcaa
     1081 gatagacgat taccatttct tcctccccaa atagtaagct aaaagcaggc ctccaccgat
     1141 actcaaaagc aaatacagta tcaaactaag ataacgccct gtatcaagca gcttcacagt
     1201 atcaagcatt aggctggaaa aagttgttaa acctccgcaa aaacccgtcc ccagtgctaa
     1261 aatcaagccc ttactagtcc ccttatagac cagatagccc ttgacaagat aaatcaagca
     1321 gaaaattccc agatagttga caaagagagt gccccaaggg aaatctggac tggctggtaa
     1381 ccaagtggaa actaggtagc ggacaagtcc gcccaacata gcagctagaa aaatccctag
     1441 cggataaaat tgttcttttt tcatttgata ttttgatcct gataatcacg cgaacgtttg
     1501 agtatgtccg aaaaagtcgc gacaatagtc tcctgatagc gcttgtcctc tacacgactt
     1561 ctaacctttt caaaaataac tgcttctctc ttagtatcta aaatcggttt ccctgaagcc
     1621 ttcttataag cgacaactcc ttcaactaag tgcattcgtt cttctaacag tttgacaatt
     1681 tggtcgtcga tttgatcgat ttcttgacga ataatatcta aatccataca gtctcctcct
     1741 ttatttgaat tattgtatca aaaagccatc aattaggcta gtaaaatccc aactctcgat
     1801 aagaaaaatg cactgattga ttacatcagc gcacttttat gcttatccta ctttagcagc
     1861 caattcttct gcgaattgtt ccaagcgttc aatatcttct tcctcggcag aaagatcaac
     1921 tttaacacac tctgaacctt tttctgctcc tgttgacaca aagacacggt caaagtcatc
     1981 aacagcctta caaaattcat cgtagaaggt atctcctgag ccgaccactc cgtagatttt
     2041 gccattcaag ttgagatctg ctaggtcttc gtagaagtcc atcatctcat ctggcaattc
     2101 accatcacca taagtatagg tcgcaacgat agcgatgtct gcttccaaga agtctgaagc
     2161 gtcaacagtt gtacattcat caacatcaac atccaagccc aagtcacgta atttgtctgc
     2221 tacaatatct gcaatttctt cggtattacc ggtcatactg gcaaatacaa tttttgctaa
     2281 tgccatatcg tcctcctcaa tttatctttc tccattatat cacatctttt tcattttaaa
     2341 aataaaaatt cttgtgctac aatgaaatga gaaagaattg aggttattta tggagatttg
     2401 ccaacaaatt ttagaaaaaa ttaaagaata cgacaccatt atcattcatc gtcatatgaa
     2461 accagaccct gatgccttgg gaagtcaggt gggattgaaa gccttgctag aacatcattt
     2521 cccagaaaaa accatcaaag ccgtcggttt tgatgaacca actcttactt ggatggctga
     2581 gatggatctt gttgaagata gagcctacca aggcgcactt gtcatcgtct gtgatacagc
     2641 taatactgct cgtatcgatg ataagcgcta tagtcaaggt gattttctca ttaagattga
     2701 ccaccatcca aatgatgatg tatacggtga cctgtcttgg gtcgatacta gttcaagtag
     2761 cgctagcgag atgattaccc tatttgccca aacaacccaa ctagccttgg cagatcgcga
     2821 tgctgagttg ctctttgcag gaattgtcgg tgatacaggt cgcttcctct acccttctac
     2881 cactgcacgg actcttcgcc tggctgctta tttgagagaa cataactttg actttgcggc
     2941 tctcactcgc aaaatggaca ctatgagcta caaaattgct aaactgcaag gctacatcta
     3001 cgaccatctg gaagtggatg aaaatggtgc tgctcgcgtt atcctgagtc agaaaatctt
     3061 gaaacaatac aatataaccg atgctgaaac tgcggccatt gtaggtgcac ctggacgcat
     3121 tgacagagtg agtctctggg gaatttttgt cgaacaggct gatggccact accgagttcg
     3181 cttacgcagt aaagtccatc ctatcaatga aattgccaag gagcatgatg gtggaggcca
     3241 ccctctagca agtggtgcta attcctatag cctagaagaa aacgaaatca tctaccaaaa
     3301 gttaaaaaac ttgcttaaaa actgataaaa tacttgccaa acttttcaga atctgataga
     3361 ctagtatagt aacaatctat ggctcgcaaa gagaccatgg cagaaaggaa atattgcaaa
     3421 atgaaaaaag atatccatcc agaatatcgc ccagttgtct tcatggacac aactactggt
     3481 taccaattcc ttagcggttc aacaaaacgc tctaacgaaa cagttgagtt cgaaggcgaa
     3541 acttacccat tgatccgtgt ggaaatttca tcagactcac acccattcta cactggacgt
     3601 caaaagttca ctcaagcaga tggacgcgtg gatcgtttca acaaaaaata cggtctcaaa
     3661 taatgataag agaacagttt tggctgttct tttttgtttc ttgaaatcaa ctgctgattt
     3721 catgttccag actcatctgt aggttcgatt tccatgctac taggcaggaa ggaaatagct
     3781 gtttcaacac gtccataatg agctatacta ttgtcacgaa ccacactttc attgatggtc
     3841 caagtggaat tcattttctt aaaagcttct cggacttttt ccaaatcttt ggaggcaatg
     3901 gcctgctcta aggtttcaaa acgaggactt atactcatct gctttcaaaa agcattctag
     3961 tccatctccg attaccgatg gactttatca cctccttctc cagtccttgt atgacatctt
     4021 gaagttgatt catgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac
     4081 gaatctcttt ccacacttgt tcaatgggtt catctctggt gtgtatggag gaataaaggt
     4141 aaaatcaata ttagtcggaa tatttaaggt acttgattta tgccatatag cattgtccat
     4201 aacgagtaaa aggataagct tgtgaaagct cttctaaaaa ggcgttcatc cacactcctt
     4261 tttataaacc tgaaataagg catcaattgt aacaaattct cctgcctctg tagccttcaa
     4321 atgacgggca agaaaggctt tctcttcctc aactgtcata tatgcatggt tacgaccacc
     4381 acgtgtttct tgaaggagag agtcgagtcc gaactcctca tattttttta cgtttcgcca
     4441 aatcgttgtt tgattacagt ctaaaagctc tataatctct ttataagatt tgcccatcag
     4501 acgaaatata gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa
     4561 atcgatttgt cctgttcttg tttcatttta ctatagaacg atttgaaggc gtttataata
     4621 tttagctgta cgagagtctt ttaaaagtgt tttgatggtt tggatttctt ctt
//
LOCUS       DAVLAQ010000092         4655 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000092 DAVLAQ010000000
VERSION     DAVLAQ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.092"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..657)
                     /locus_tag="VXB71_001947"
     CDS             complement(<1..657)
                     /locus_tag="VXB71_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0452002.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     Y"
     gene            complement(945..1907)
                     /gene="nrdF"
                     /locus_tag="VXB71_001948"
     CDS             complement(945..1907)
                     /gene="nrdF"
                     /locus_tag="VXB71_001948"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0452003.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2095..4254)
                     /gene="nrdE"
                     /locus_tag="VXB71_001949"
     CDS             complement(2095..4254)
                     /gene="nrdE"
                     /locus_tag="VXB71_001949"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0452004.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4335..4553)
                     /gene="nrdH"
                     /locus_tag="VXB71_001950"
     CDS             complement(4335..4553)
                     /gene="nrdH"
                     /locus_tag="VXB71_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0452005.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
BASE COUNT         1357 a          859 c          952 g         1487 t
ORIGIN      
        1 ataaaaatca aacttattga acttactatg atctgcgagt aaatattttt tattagaatt
       61 atttaaagcg atgcgttgag cctctccctc ttcctcgcta aaagtagcta gagctccgtt
      121 ttgaatacca ttacagctaa cgaaagcttt agaaaattgg agattagaga gattttgtag
      181 ggtcaatgtg ccaacaaaag cacctgtaat atcgcgataa tttccaccta tcaaaatcaa
      241 atctgttaat tttcgttcgc ttaaaatcag aaaaacaggt agactgttgg ttacgacgcg
      301 gatattgtca ataggcaact cacgcgcaaa aaactctaat gttgttcctg gtccaatgaa
      361 aatagtttct ctttcttcta ctagactgcc tgcaaaatgg gctatttctt gtttttctgc
      421 cgtttggagg gcttgttttt caatatttga tcgctcatta gtcaaaaggg agttggttcg
      481 aagtttttca gctccaccat gcacacgaat cagcaaatct ttatcagcta attcctgtaa
      541 atagcgcctt gcagtcatat ctgaaacggc tatttcgtcc ataatctgtt taactgttat
      601 ggttccttta ctatttacta tctctaaaat tttggttaat ttttcttgtt tgagcatatt
      661 atcacctcgt ttcctactac tatcttacca taaacaaact catcattcaa atacaaaaac
      721 aacaaaatga aacaaaaaca aaaatatcga agtttgtttt caaaactttc gatatttttg
      781 ttgggttatt attttgttgt ttctagttta ctttttgatg gttaagagtg gtggagaatt
      841 atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggctgta cttgagtacg
      901 gcaaggcgaa gctgacgtgg tttgaatttg attttcgaag agtattagtc caaaccgtag
      961 ttgtagtcat catcttgcat ggcttcaact tcgccaagaa ggtaaccatt tccgacttga
     1021 gagaagaagt catggttgga agttcctgtt gaaataccgt tcataacgat tgggttgaca
     1081 tcttcagctg aatctgggaa aagtggatct tgtcccatgt tcatgagagc tttattggca
     1141 ttgtagcgaa ggaaggtttt aacctcttca gtccaaccaa caccgtcata aagactctct
     1201 gtgtagcctt cttcattttc ataaagagta tagagtaggt cgtacatcca ttctttgagt
     1261 ttttcttgct cttcttcagg taattcattg aaaccaagtt ggaatttgta accaatgtag
     1321 gttccgtgaa cagactcgtc acgaataatc aatttaatga tttctgcaac gttggcaagt
     1381 ttgttgttac cgagatagta gaggggagtg aagaaaccag agtagaagag gaaggtttcg
     1441 aggaagacgc tggcaacttt cttttcaagt gggctgccgt ttaggtagat ttcgttgaca
     1501 atctcagcct tcttttgtag gtaaggattg gtattggtcc attcgaaaat ttcttcaatc
     1561 tcagccttag tattcaaggt agaaaagatt gatgagtaag atttagcgtg gacagattcc
     1621 ataaattgga tgttattgaa aacagcttcc tcatgtggtg tacggatgtc tgcgcgaagg
     1681 gcttgaaccc cagtttcaga ttgcatagtg tcaagaaggg ttaaaccacc aaaaactttt
     1741 ccgaccaagt ctttctcttt gttagatagc tttctccagt catccaagtc gtttgataag
     1801 ggaatacgtg tatcgagcca aaattgctcc gtcagttttt cccaagttga tttgtcgatg
     1861 acatcttcga tggcattcca gttaatggct ttgtagtaag tttccattta aaatctcttt
     1921 ctgtgtttag tattgcgaac tcacaattat ttctacttta ccataattct ataggagtat
     1981 cgcacaaaaa gtcggaagcc cgacttttaa aatgttacat aaattatgtt atgacatagt
     2041 agatttgatt ttatcagtgc tgcttaggga aaaatagtgt ttctatgcta gaaactaaat
     2101 cacacagctt tcacattggt tggcgccgac ttctccaccg tcatctgtaa aggtacggac
     2161 gtagtagata gacttgattc ccttgttaaa ggcatagtta cgaaggatgg acaagtcacg
     2221 tgtcgtttgt ttattttccc tcttccattc gtaaaggcct tttggaatgt cactacgcat
     2281 gaagagggtg agtgaaagtc cttgatccac gtgttcagtc gcagcagcgt aaacatcgat
     2341 gactttacgc atatccatat cgtaggcaga agtgtagtaa ggaatggttt ctgtagacaa
     2401 gccagcagca gggtagtaga ttttaccaat tttcttttcc tgacgttctt caatacgttg
     2461 cgtaatcggg tggatagaag cagaaacatc gttgatgtag ctgatagaac catttggcgc
     2521 tacagcaagg cgattttggt ggtaaagacc atcctcttga accttgtcgc gaagttcagt
     2581 ccaatcagca acaccaggga taaaaacatt tttgaagagt tctttaacac ggtctgatgt
     2641 tggaacaaat tcaccagtta catacttgtc aaagtaactt ccgttagcat agtctgattt
     2701 ttcaaagttg tggaaggtaa taccacgttc acgcgcaata ttgtttgact ctaccaaggt
     2761 ccagtagttc ataagcataa agtagatgct tgtaaattca acagactcag gtgaaccata
     2821 ttcaatgagt tgttgggcaa ggtagctgtg cagtcccatg gcaccgagac caaaggtgtg
     2881 ggcttggcta tttccatggt caatcgttgg tacagctacg atatgtgaac tatctgtaac
     2941 gaaagtaagg gcacgaacca tagcacggat agaacgacca aaatcaggtg aagtcatcat
     3001 gttaaccacg ttggttgaac ccaggttaca tgaaacatct gttcccattt gaaggaattc
     3061 ttgagcatcg ttgatcaagc ttggttcttg aacttgaaga atctcagaac acaagttact
     3121 catgataatc tttccatcga caggatttgc acggttagcc gtatctatgt tgactacata
     3181 aggatagcca gactcttgtt gcaatttaga gatttcagtt tccaaatccc gcgccttgat
     3241 ttttgtcttg cgaatatttg gatttgcgac caattcatcg tatttttcag taatgtcgat
     3301 gtaattgaat ggcacaccgt attctttttc tacagagtaa gggctgaaga ggtacatttc
     3361 ttcattttta cgagccaatt cgtagaattt atcaggtact acaacaccaa gtgatagagt
     3421 cttgacacgt actttttcat cagcgttttc tttcttagtt gaaaggaaag cgatgatatc
     3481 tgggtgaaag acgttgaggt agacaacacc ggcaccttga cgttgcccca attggttgga
     3541 gtaagagaag ctgtcttcaa aaagcttcat aacaggaacg acacctgaag cagctccttc
     3601 atagcctttg ataggtgcac cagcttcacg aaggttgctg agggtaattc ccacaccacc
     3661 accaatacgt gaaagttgaa gagctgagtt gatagaacgt ccgatagagt tcatatcatc
     3721 cgtcacttgg attaggaaac aagataccaa ctccccacga cgagcacgtc cagcattcaa
     3781 gaaggaagga gtagcaggtt ggtagcgttg gtggatgatt tcattggcaa tatcgattgc
     3841 aacagcttca ttcccatcag cgaaataaag ggcgttgaag aagacacggt cttccatatt
     3901 ttcaagatag tattcaccgt cattagtctt taaggcatat tgattgtaaa atttataagc
     3961 tgccatgaat gacttgaatt ggaagttttg gtctttgata aattgagcca attcttccaa
     4021 gaactctgga cggtatttct tgataaaggc tgtttcgatg tagttgtgtt caatgaggta
     4081 attgattttg tctttgattg aatcaaaaac catagtgttt ggaactacat tttctttaaa
     4141 gaaagcatcc aaggcttcct tatctttatg aagcatgatt tgtccattaa caggacggtt
     4201 aatttcgtta ttaagacgga agtaagtcac gtcttcaaga tgttttaatc ccataaaatt
     4261 tcccttatct aattacaaaa gaaaggcttc taagttagcc ctaaaagcag tttcttctgg
     4321 atgatgtact aagattatgc taattgtttc agtttttctg gttggaaacc tgaaaagact
     4381 tcagttggtg tttggataac aggagctgcg ctaaaaccga gctctttaac ttgatcgacg
     4441 tactcaggtt gctcatcaag attgatttca cgataagaga cattattact gtccaagaaa
     4501 cgcttggtca ttttacattg gacacaattg tttttagaat aaacggttac cattgtgtaa
     4561 ctcctcttca aaatttaata ctatcttagt atatcagaaa ataaaatttt gtcaatgatt
     4621 taaactaaat atagtggtgt tcttttgttg ttttt
//
LOCUS       DAVLAQ010000093         4556 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000093 DAVLAQ010000000
VERSION     DAVLAQ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.093"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            527..736
                     /locus_tag="VXB71_001951"
     CDS             527..736
                     /locus_tag="VXB71_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0452006.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            726..1214
                     /locus_tag="VXB71_001952"
     CDS             726..1214
                     /locus_tag="VXB71_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452007.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            1330..2790
                     /locus_tag="VXB71_001953"
     CDS             1330..2790
                     /locus_tag="VXB71_001953"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0452008.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            2787..3611
                     /gene="nadE"
                     /locus_tag="VXB71_001954"
     CDS             2787..3611
                     /gene="nadE"
                     /locus_tag="VXB71_001954"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0452009.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            3961..4512
                     /locus_tag="VXB71_001955"
     CDS             3961..4512
                     /locus_tag="VXB71_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0452010.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         1356 a          851 c         1034 g         1315 t
ORIGIN      
        1 attgaacttc ttccttttta ttctttacct gtatttgtgg cttcaaatac gatgtctatt
       61 agtcagtatc ttgtggtaat cactacaatc attttattgt actttttcac tctcaagaaa
      121 agcaagaagt attcatttta gtttcattta gtattatttt gcatacctaa aatacaataa
      181 aaaaatcagt catcttggta tgctcctgct ttcactattc aacacgtttt tgacttatac
      241 taggctcatt tccaaaagca ttatataata gtgatatgaa accaactaaa ctaaacaaga
      301 aatataagca ataaaaactc gtttaaaaga tcctactaaa gctaatacta aataaaaata
      361 aaagagtaaa ctaggaagtt tatttcaaac aacctaaaat actgattttc ggctgaagat
      421 aatactggag tgcaaattaa tggggttata ataaatagct gatagcttgt gttggttttg
      481 gattttttaa gagtagatga gtattaaaac tataaggagg acgaaggtgg ctaaaaattt
      541 aaaattaaaa ttagctcggg tagagcgtga tttaacacaa ggtcaactgg cagaggctgt
      601 cggggtgacg cgccagacta ttggtttgat agaagcgggg aaatacaatc ccagtctctc
      661 gctctgccag tccatttgca gatgtttagg gaaaacccta gaccaactat tttgggagga
      721 agaagatgaa aaatagattt tattattatc aattactaga cgaaagagaa gaacaactgt
      781 tcaataaagc gggctctgaa agtttctata tctgcatcgc tttgtcgctc ctatcttata
      841 tcatttcagt attagcacca agccttttta attctaatat gctgctaatc gttatcatca
      901 tagggacatt ttactttttc aatcgtgccc gttatctggg agtgacctac tatagtcgtt
      961 ttcattttac gattttgggt tgttttttcc taaccttggc tattacggct cttttgatgt
     1021 tgcagaatta tcaattcaac atagaaattt atcagcacaa tcctttgaat tttaaatacc
     1081 tgtctgcttg ggtcattact tatatcattt accttccgtg gatctttatt ggcaatcttg
     1141 gtcttaagag ctatggcgaa tgggctcaga aaaaatttga acaagatatg gatgaattgg
     1201 agagtggaga atagcttgtt actcttttct caatccagct aaaatgtgat ataatagtac
     1261 taatttattg gaatacatga aagttcttga aaattttcat gggtttctag ctaaggaagt
     1321 aggaaaagta tgtatccaga tgatagtttg acattgcaca cggacttgta ccagatcaac
     1381 atgatgcagg tttactttga ccaagggatt cacaataaga aggcggtctt tgaggtgtat
     1441 ttccgccaac agccttttaa gaacggctat gcggtttttg caggtttgga aagaattgtg
     1501 aactatcttg aagacttgcg tttttcagat agtgatatag cctatttgga gtcgcttggt
     1561 tatcatgggg cgttcttgga ttaccttcgc aatttcaagt tggagttgac cgttcgttct
     1621 gcccaagaag gggatttggt ttttgctaat gaaccgattg tgcaggtgga aggacctcta
     1681 gcccaatgtc agttggtcga aacggctctt ttgaacatcg tcaactacca gaccttggtg
     1741 gcgacgaagg cagctcgtat tcgttcggtt atcgaagatg aacccttgat ggagtttggg
     1801 acacgtcggg ctcaagaaat ggatgcggcc atctggggaa cacgcgcagc tgtgattggt
     1861 ggcgccaatg gaactagcaa cgtgcgtgcg ggtaagctct ttgacattcc tgttttggga
     1921 acccatgccc atgccttggt acaggtttat ggcaatgact atgaagcttt caaggcttac
     1981 gctgcgaccc acaaaaattg tgtctttctt gtggatacct atgacaccct tcgcatcggt
     2041 gtaccagctg ccattcaggt ggcgcgtgag ctgggtgatc agattaactt tatgggtgtg
     2101 cggattgact ctggggatat tgcctacatt tctaagaaag tccgtcagca actggacgag
     2161 gctggattta cagaggctaa gatttatgct tctaatgatt tggacgaaaa tactatcctc
     2221 aatctcaaga tgcaaaaggc caagattgat gtctggggcg tgggtaccaa gctgattaca
     2281 gcctatgacc agccagctct tggtgcagtt tacaagattg ttgcaatcga agatgaaact
     2341 ggtcagatgc gcaatacgat taagctgtct aataatgctg aaaaagtttc tacgccaggt
     2401 aagaagcagg tgtggcgcat taccagtcgt gaaaaaggca agtcagaagg cgactatatc
     2461 acttatgatg gtgtggatat tagcgacatg acagaaatca agatgttcca tccgacctat
     2521 acatacatca agaagacggt tcgtaatttt gatgccgttc ctctcttggt ggatatcttc
     2581 aaagaaggaa tattagttta caacttgcct agtttgactg acattcagga ttatgcccgt
     2641 aaagaatttg acaagttgtg ggatgagtat aagcgtgtgc tcaatccgca gcactatcca
     2701 gtggatttgg cgcgtgatgt atggcaagat aagatggact tgattgataa gatgcgcaag
     2761 gaagcccttg gtgaaggaga agaagaatga gtttgcaaga aacgattatc caagagctgg
     2821 gtgtcaaacc agtgattgat gcccaggaag aaatccgtcg ttctattgat ttcttaaaaa
     2881 gatatctgaa aaaacatccc ttcctaaaaa cctttgtact agggatttct gggggacaag
     2941 actcaacctt ggcagggcgt ttggcgcaat tagctatgga agaactgcga gctgaaacgg
     3001 gagacgatag ctacaaattt atcgctgtcc gcctgccata cggagtgcaa gctgatgaag
     3061 cagatgctca aaaagctcta gccttcatcc agccagatgt cagcttggtt gtgaatatca
     3121 aggaatcagc tgatgccatg acagctgcag ttgaagcgac aggtagtcct gtttcagact
     3181 tcaacaaggg gaatatcaag gcacgttgcc gtatgattgc tcagtatgcc cttgctggtt
     3241 cccatagcgg agcggtcatt ggaacagacc acgccgcgga aaatatcaca ggtttcttta
     3301 ccaagtttgg tgacggcggt gcggatattc tccctcttta ccgcctcaat aaacgccaag
     3361 gaaaacagct cttgcagaaa cttggcgcag agccagccct ttatgaaaaa atcccaacgg
     3421 cagacctaga agaagataaa ccaggcctag ctgacgaagt cgcacttgga gtcacctacg
     3481 cagagattga cgactaccta gaaggcaaaa caatcagccc agaagctcaa gcgaccattg
     3541 aaaactggtg gcacaaaggc caacacaaac gccacttacc catcactgta tttgatgact
     3601 tttgggagta aaaaggtccg ggggaccttt ttagcttctt gccctgaaat taaaaagcaa
     3661 gaaaaacctc cactggaggt tttcagcctc tcatcttaaa ataagaaagt gagagaaggt
     3721 ctgggggatc ttgaaccccg agtttagaaa taagaaaatg aggcagattc ggtaactcga
     3781 agagttcgat ttcatcgtct tacccctgca acgatgacta ggtttgaaaa agcttgctag
     3841 atcgcatttc aaaccaggca gcgattgcgt caagaaatta gaagacaaac tcgttttcta
     3901 gctgttactg agttgagcct ttttactacg agcatagaaa taaggaagtg aggtagcatc
     3961 atgaaatcta ttggtacgca aatattacag acagaacgtt tgattttaag aagatttgtg
     4021 gagagtgatg cagaagctat gtttcaaaat tgggcttcat ccgctgagaa tctgacctat
     4081 gttacctggg atccccatcc tgatatcgaa atcactcgaa actcgattcg caattgggtt
     4141 gcttcctata ctaatctcaa ctattataaa tgggccattt gtctaaaaga aaacccagag
     4201 caagtgatag gagatatcag cattgttaag atagacgagg ctgatttaag ctgtgaaatc
     4261 ggctatgtgc taggcaaggc ttactgggga catggtatga tgacagaggc cttgaaagct
     4321 atcttggact tttgttttac tcaagcaggt tttcaaaagg tcagagcacg ttatgccagt
     4381 ctcaacccag cttcaggtcg tgtcatggaa aaggctggaa tgtcctatct acaaaccatt
     4441 gttaatggtg tagagagaaa aggctatctt gcggatctta tttattatgg tataagtagg
     4501 gaagaatgtt gaattctatt ttctgtttct atcgaagtca actatttatt gtaaat
//
LOCUS       DAVLAQ010000094         4289 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000094 DAVLAQ010000000
VERSION     DAVLAQ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.094"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            4..321
                     /locus_tag="VXB71_001956"
     CDS             4..321
                     /locus_tag="VXB71_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0452011.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     DAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            323..2017
                     /locus_tag="VXB71_001957"
     CDS             323..2017
                     /locus_tag="VXB71_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0452012.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            2232..3638
                     /gene="lacG"
                     /locus_tag="VXB71_001958"
     CDS             2232..3638
                     /gene="lacG"
                     /locus_tag="VXB71_001958"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0452013.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            3728..3940
                     /locus_tag="VXB71_001959"
     CDS             3728..3940
                     /locus_tag="VXB71_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0452014.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
BASE COUNT         1343 a          716 c          861 g         1369 t
ORIGIN      
        1 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
       61 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
      121 gacgctctgg tagaggacgc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
      181 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
      241 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
      301 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
      361 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
      421 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
      481 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
      541 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
      601 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
      661 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
      721 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
      781 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
      841 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
      901 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
      961 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     1021 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     1081 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     1141 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     1201 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     1261 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     1321 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     1381 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     1441 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     1501 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     1561 tgaccatcaa attttagaag aagaacggaa aggaaactct tcatctgaat tgaaagaaaa
     1621 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag caggtgtcga
     1681 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg ctggtggagg
     1741 tacaagtgga ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     1801 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatttggt
     1861 tatccttgct cctcaagttg cttcaaactt tgaagatatg aaggcagaaa cagataagct
     1921 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     1981 aggtgcccta gcattcgtac aagaacaatt cgattaaggc taggaactgt gaaacagtct
     2041 cctatcgtta cggaaatcgc tatggcgaat ttcctaatcg ccttattaat tcgtcggtaa
     2101 aaagatatcg tttttacctc ctcatgtcac aattcggtga cttggtacaa gaagtgagat
     2161 ggagaaggat ggctcactga ctcctctcct ctcactttta ctttatttaa atcaagaaat
     2221 aggtgaaaaa aatgacaaaa acacttccaa aagactttat ttttggtggc gcaacagctg
     2281 cctatcaagc agaaggtgct acacatactg atggtaaagg accagtagcg tgggataaat
     2341 atcttgaaga taactactgg tacactgcag aaccagccag tgatttttac aatcgatatc
     2401 cagttgatct caagctagca gaagagtatg gtgtcaatgg cattcgaatt tctattgcct
     2461 ggtcacgtat tttcccgact ggttatggtc aagtaaatgc taaaggtgtt gagttttatc
     2521 ataatttatt tgcagagtgt cacaaacgtc atgttgagcc ctttgtaact cttcatcact
     2581 ttgacacgcc agaagctctc cactcaaatg gagacttctt aaaccgtgaa aatatcgaac
     2641 attttgtaga ctacgctgcc ttctgttttg aagaatttcc agaagtaaac tattggacaa
     2701 ccttcaatga aattggacca atcggtgatg gtcaatattt ggttgggaaa ttccctccag
     2761 gtatccagta cgaccttgcc aaagtctttc aatcacacca caatatgatg gtgtctcatg
     2821 catgcgcggt aaaattgtac aaagagaaag gctataaagg ggaaattggt gttgttcacg
     2881 ccctgcctac taaatatcct ctagatcctg aaaatccagc agatgttcgt gcagcagagt
     2941 tggaagatat catccacaat aaattcatct tagacgcaac ttatctaggt cgctattcag
     3001 ctgaaaccat ggaaggtgtc aaccatatct tatcagtcaa tggtggtagt ttggatcttc
     3061 gtgaagaaga ttttacagca ttagaagctg caaaagactt gaatgatttc ctaggaatca
     3121 actactatat gagtgactgg atggaagcct ttgatggaga aactgaaatt atccataatg
     3181 gtaaaggtga aaaaggaagc tctaagtatc aaatcaaagg tattggtcgt cgtgtagctc
     3241 ctgactatgt atcacgcacg gattgggatt ggattatcta ccctcaaggt ttgtatgacc
     3301 aaatcatgcg tgtgaagaaa gattatccta actacaagaa gatttacatc actgaaaatg
     3361 gtctcggcta taaagatgag ttcgttgata acactgttta cgatgatggt cgtattgatt
     3421 acgtgaaaca acacttggag atcttgtctg atgcgattgc agatggagct aatgtaaaag
     3481 gttacttcat ttggtcatta atggatgtct tctcatggtc aaacggttat gagaaacgtt
     3541 atggtctctt ctacgtagat tttgaaactc aagaacgtta tcctaagaaa tcagctcact
     3601 ggtacaagaa agtagcggaa actcagatta tagactagta gaattagtca ttagatatag
     3661 aattttagtg agtcaaaaag atgttcaaag attttatcca atctatttat gaaaaaaagt
     3721 ttatattata aatttcgaaa aatgctctca aataccgtgt ttgacgagtg aagaattgaa
     3781 aagtcttgga aaatggtatg tctcgactgg taaagaatgg atttgtcatt cagatgatga
     3841 gctggaagaa tttaaaaatc tatttttaaa ttttatcaat cctgaagaat gggatactat
     3901 ctcctttgat tcagatttta tgccgtttca acaatcgtaa ccaatttctc aaaaaagtta
     3961 aatcttatat ttagtactct gtaaaactct tatctaatca cgttgcttat actcaatgaa
     4021 aatcaaagag caactttaaa ctaggaagcg agtcgcagat ttctcaatgc atagctttga
     4081 ggaattgggc aaaaagtctt tgatatagaa aaaagcatag tatcaggtgt tgaaacacct
     4141 gatactatgc tttttattgt gggaagattt actttttttc ttctgaaatt gagttgttac
     4201 ccaggctctt tcagtttatt aaggcttgat gactttaatg tgtttagata gcttaaaaag
     4261 gattgaatca cttagtttag aatctgaaa
//
LOCUS       DAVLAQ010000095         4042 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000095 DAVLAQ010000000
VERSION     DAVLAQ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.095"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            626..1618
                     /locus_tag="VXB71_001960"
     CDS             626..1618
                     /locus_tag="VXB71_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0452015.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1620..2438
                     /locus_tag="VXB71_001961"
     CDS             1620..2438
                     /locus_tag="VXB71_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0452016.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2440..3225
                     /locus_tag="VXB71_001962"
     CDS             2440..3225
                     /locus_tag="VXB71_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0452017.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3323..3541
                     /locus_tag="VXB71_001963"
     CDS             3323..3541
                     /locus_tag="VXB71_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0452018.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3526..3687
                     /locus_tag="VXB71_001964"
     CDS             3526..3687
                     /locus_tag="VXB71_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0452019.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1116 a          691 c          886 g         1349 t
ORIGIN      
        1 attgaaaaat ttatacgaga tgatgaaagc cttaagtgtt attttacaaa ggttatttca
       61 agtcgttcca aggtaacaag tctagatcag attgaagctg ataaaacgat acaaagaaaa
      121 tattcaagtg agctaaaaaa atttattgga ttttataatg agattatttg tgaggaaaat
      181 agtttcctac atgtacgaaa gaggtggtcg agttggttta ggtagtcggt gcgtgagttg
      241 ataattctca gggtatggac ttctttttca tgaatgaggt aaaagagcag gtattgttta
      301 gagacaatca ttctgagcat attttctgga tagagggagt atccgatttt atgatcaaag
      361 ttaataccgc cctctggtga gaagatgagt aggttggtaa tttaaactat taaacagaat
      421 ttttgattaa aagtattatt tcatgagaga aatcctaatt tcacaatcta taggcaaacg
      481 cttgcatttc gttttttatt ggactataat aggttggtat aaagccttct gtagtaataa
      541 aatgtagaag gtgtagaaag taaggattta gaatatttgt agttaaaaac acaatgttgc
      601 tattccttac gatagggaga tagatatggc aatgatagaa gtggaacatc ttcagaaaca
      661 ttttgtgaag attgttaagg aaccgggctt gaagggggct ttgcgctcct ttattcatcc
      721 tgaaaagcag acctttgaag cggtcaagga tttgaccttt gaggttccaa aagggcagat
      781 tttaggattt atcggggcaa atggtgctgg gaagtcgaca accattaaaa tgctgacagg
      841 aattttgaaa ccaacatctg gtttttgtcg gattaacggc aagattcccc aggacaatcg
      901 gcaagattat gtcaaagata ttggcgtagt ctttggacaa cgcacccagc tatggtggga
      961 tttggctctg caagagacct acactgtctt aaaagagatt tatgatgtgc caaactcgct
     1021 ctttcataag cgtatggact ttttgaatga agtcttggat ttgaaggact ttatcaagga
     1081 tcccgtgcgg actctttcac tgggacaacg gatgcgagcg gatattgcgg cctccttgct
     1141 ccacaatccc aaggttcttt ttttagatga gccgaccatt ggtttggacg tttcggttaa
     1201 ggataatatt cgtcgggcaa ttactcagat caatcaagag gaagaaacta ccattctttt
     1261 gaccactcac gatttgagtg atattgagca actttgtgat cggattttca tgattgacaa
     1321 ggggcaaaag atttttgatg gaacggtgag ccaactcaag gagacctttg gtaagatgaa
     1381 gactctctct tttgaactgc taccaggtca aagtcatctc gtctctcact atgaaggtct
     1441 gtctgatatg accattgata gacaaggaaa cagcctcaac attgaatttg atagttctcg
     1501 ctaccagtca gctgacatta tcaagcaaac cctatctgat tttgaaatcc gcgatttgaa
     1561 gatggtggat acggatattg aggatattat ccgtcgcttc taccgaaagg agctctagga
     1621 tgatcaaatt gtggagacgt tataaaccct ttatcaatgc aggggttcag gagttgatta
     1681 cttaccgagt caactttatt ctctatcgga ttggcgatgt catgggggct tttgtggcct
     1741 tttatctctg gaaggctgtc tttgattctt cgcaagagtc tttgattcag ggcttcagta
     1801 tggcggatat caccctctac atcatcatga gttttgtgac caatcttctg actagatccg
     1861 attcgtcctt tatgattggg gaggaggtca aggatggctc cattatcatg cgtttgttgc
     1921 gaccagtgca ttttgcggcc tcctatcttt tcaccgagct tggttccaag tggttgattt
     1981 ttatcagcgt tggccttcca tttttaagtg tcattgtctt gatgaaaatc atatcgggtc
     2041 aaggtattgt agaggtgcta ggattaactg tcctttatct ttttagctta acgctcgcct
     2101 atctgattaa ctttttcttt aatatttgct ttggattttc agcctttgtg tttaaaaatc
     2161 tttggggttc caacctactt aagacttcca tagtggcttt tatgtcgggg agtttgattc
     2221 ccttggcatt ctttccaaag gttgtttcag atattctctc ctttttgcct ttttcgtcct
     2281 tgatttatac tccagttatg atcattgttg gaaaatacga tgccagtcag attcttcagg
     2341 cactcctttt gcagttcttc tggctcttag tgatggtggg attgtctcag ttaatttgga
     2401 aacgggtcca gtcctttatc accattcaag gaggttagta tgaaaaaata tcaacgaatg
     2461 catctgattt ttatcagaca atacatcaaa caaatcatgg aatataaggt ggattttgtg
     2521 gttggtgtct tgggagtctt tctggctcaa ggcttgaatc tcttgtttct caatgtcatc
     2581 tttcaacata ttccattcct agaaggctgg acctttcaag agatagcttt catttatgga
     2641 ttttccttga ttcccaaggg aatggaccat ctcttttttg acaatctctg ggcactaggg
     2701 caacgcctag tccgaaaagg agagtttgac aagtatctga ctcgtcccat caatcctctc
     2761 tttcacatcc tagttgaaac ctttcagatt gatgccttgg gtgaactctt agtcggtggt
     2821 attttattgg gaacaacagt gaccagcata gtttggactc ttccaaaatt cctgcttttc
     2881 ctagtttgta ttccttttgc gaccttgatt tatacttctc ttaaaatcgc aacagccagt
     2941 atcgcctttt ggactaagca gtcaggcgcc atgatttaca tcttctatat gttcaatgac
     3001 tttgctaagt atccgatttc tatttacaat tctcttcttc gttggttgat tagctttatc
     3061 gtgcctttcg cctttacagc ctactatcca gctagctatt tcttacagga aaaggatgtg
     3121 ttctttaacg taggaggttt gatgttgatt tctctggttt tctttgttat ttcccttaaa
     3181 ctttgggata agggcttaga ttcctacgaa agtgcgggtt cgtaaaagct aaagtaagac
     3241 taaaatcaag aaaggaactt atgatgtttg taattgaaga agtcaaggat gaaaatcaaa
     3301 aaaggcagtt gtcgttgagg ttttgaagga tttgccagaa tggtttggaa tcccagaaag
     3361 cacacaagcc tatatagaag gaaccacgac actgcaagtt tggaccgcct atcaggagag
     3421 tgatttgact ggatttgtaa ggttatccta ttcgagtgaa gattgtgcag agattgattg
     3481 tctcggcgta aaaaagctta tcaaggtaga aaaattggga gccaattgct tgctacttta
     3541 gagagtgaag ctcgtaaaaa agttggttat ctgcaggtca aaacagtggc agaaggttct
     3601 aataaagatt atgatcgaac aaatgacttt tatcgaggtc ttggctttaa aaagttagag
     3661 attttttctc agctatggaa tccgtaaaat ccttgtcaga ttttgattaa aaagcttgaa
     3721 taatattact tgacatctat tctcagagtg ccatactgta agtgtaatcg ccgatttagc
     3781 tcagttggta gagcaaggca ctcgtaaagc ctaggttata ggtagataaa cgactgagga
     3841 gttgaaaaaa tagataggta gaagataacc gttaagcctt attcttagcg gttatttata
     3901 ttgtttaata gcgctgatat ttcatcaatt atgcctgttt tcgtgtttct ggtagttgtt
     3961 caagtttatt gctactattt ttgatggtat gaatgtgctt ataatgtatc ccggttaacg
     4021 aaagttttgg acttatactc at
//
LOCUS       DAVLAQ010000096         4012 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000096 DAVLAQ010000000
VERSION     DAVLAQ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.096"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(213..824)
                     /gene="rpsD"
                     /locus_tag="VXB71_001965"
     CDS             complement(213..824)
                     /gene="rpsD"
                     /locus_tag="VXB71_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0452020.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1019..2071)
                     /locus_tag="VXB71_001966"
     CDS             complement(1019..2071)
                     /locus_tag="VXB71_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0452021.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2068..2766)
                     /locus_tag="VXB71_001967"
     CDS             complement(2068..2766)
                     /locus_tag="VXB71_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0452022.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGCETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2933..>4012)
                     /gene="pavB"
                     /locus_tag="VXB71_001968"
     CDS             complement(2933..>4012)
                     /gene="pavB"
                     /locus_tag="VXB71_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0452023.1"
                     /translation="MLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVA
                     LDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLI
                     SKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLK
                     ASDKAPWSDNGEAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGT
                     QTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMN
                     HNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMA
                     SIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT         1078 a          887 c          794 g         1253 t
ORIGIN      
        1 tttacgaaaa tctattgaat atgccataaa aagattatac cacattgtgt actatttttg
       61 gttcacttta ctatatcact ttggactata tcggtctagt tatgtctaaa cgattatagc
      121 tggatactaa gagaaatcaa aaaagcacta agggagaacg tcccaaagtg cttaatatca
      181 aggcctcaaa gcctatctta tttaataaaa tattacaaca ttttgttgta gaattcaacg
      241 acaagtgctt cgttgatttc tgggttgatt tcgtcgcgtt ctggcaagcg agtcaatgaa
      301 ccttccaact tttcagcgtc gaatgatacg aatgctggac gtccaagagt agcttctact
      361 gcttcaagga ttgctggaac tttcaatgat ttttcacgaa ctgagatcac ttgacctgga
      421 gttacgcggt atgatgggat atcaacgcgt ttcccgtcaa caaggatgtg accgtggttt
      481 acgaattgac gagcttgacg acgagtagtc gcgagaccaa gacggtaaac aacattatcc
      541 aaacgacgtt ccaaaagaag cataaagttg aaacctagga ttccaccttt gatttttgta
      601 gcttgtacga acaagttacg gaattgtttt tcacctacac cgtaagtgaa acgaagtttt
      661 tgtttttcag ccaattgcaa accatattct gacaatttag aacggttgtt tggtccgtgt
      721 tgtcctggta catagttacg acgtgccaat tctttacctg tacctgtaag tgaaaggcca
      781 aggcgacgag cttgtttcca agatggtcct gtataacgtg acatatgaat gtcctcctga
      841 tataaataat atttcggtgg aaatagtcac ttagaaagcc ctgattcgtg cagatgccct
      901 tcgcctaaac agccaaggtt acttgtcata agacacctgt tgacgagctt catgctttcc
      961 tgctgatatt tcacactaaa ttcattttac catgaatagc tggatttgta aaggggtttt
     1021 aggctttatt ttcactacca gagaggttga gaacgagggt aaaggtactt cctagaccgt
     1081 actggctgct gactgtgatt tccccaccca attgatgggc caattcacgc gcaatcgcaa
     1141 gtcctaatcc atgaccacct gtcttcatgt tacgcgaagt ttcgacacga taaaggcgtt
     1201 tgaaaatatt ttccaaatcc tctggggcaa taccctgccc ttcatcggtc acactgattg
     1261 aaagctggtc cttctccagc ttagccacca cttccagctt ggttcctgga gcagaatatt
     1321 taaaagcgtt atcgaccaga ttcaccaaga tacgagaaag cttagcataa tctccctcaa
     1381 tccgggcaga ctctgggatt acctgcaagt ggacatctct tctctcctgc tcaatcaaaa
     1441 actgaaattc actcatgcac tcaattaaga gcttgtccag aaaaatactg tctttactgg
     1501 tagtttccac ctgatttcta gctgtgttta gggtcaaaaa attcaactcc tcaaccagtt
     1561 tattgagcct ctccgtctgg cgtccaatgg ttgctagata atgagcttgc tccgactcct
     1621 tgataatacc atccaaaatc ccttctaccg tcgcttggat cgaagtgata ggagtcttaa
     1681 tatcatgcga caactgggca atcatcaagc ccttttctcg ttcgctttct tccaaggaat
     1741 caaagcttac ctgcaaatca tgggacatct cattaaaagt ttgccctaat tgctgaaatt
     1801 ctacaggacc ttgaacctcc aaatttgaag gaaaatcctt ggccgctacc cgcttggcat
     1861 gctccttgag tttgcccaac gacgtaaaga ctggcaatag gagaaagaga ctaatcccag
     1921 caccgacaag gctggcaacg atggtcatcc caagcaaaaa gtaaatctcg cctttcgcaa
     1981 tcagcatttt ttgaacagcc caaaaaacaa ccaaaatggt taagagggtt gaaataatat
     2041 atccaaccaa aatataactt tttagtttca tgtttgtcct ctcggtttct ctatcttata
     2101 tcccaacccc caaactgtct taatagtggg cgtttggtca ctactatatt ttgccagctc
     2161 ctgtcgaaga gcatggatat gcacattcaa ggtattggtg tcatccacgt agtcttcttt
     2221 ccagatcttt tcatagaggt ctgtcttgga gaaaactcgc tctggattgc tagctaaaat
     2281 ccacagcaat tcaaatgatt taacagttaa atccagcatt tcttctccta tttgaacttc
     2341 atgactacta tgattcattt ttagattgcc aagggaaatc agctctgttt cgcacccacg
     2401 atgaaggcgg cgcaaaatat tgtggacacg caaaactagc tcacgtgggc taaaaggctt
     2461 agcaataaaa tcatctgctc ccaagctcag gccgtaaatc ttgtcctgtt cactggtctt
     2521 agcagtaata aataggaaag gctgctctgg tgataagtat tgaacctcac tgattaaatc
     2581 ataaccatcc atccgaggca tcatgacatc tgtgataatc aaatcaatcg gttttttctt
     2641 gaacagctct agcgcttcca gtccatcatg ggctaccaag acctgataac ctgcctgaat
     2701 taagtatctc tgatgaatat ctgtgatttc tacctcgtcg tcaacgagta aaattgtctt
     2761 tcccatctgt ctctcctttg ataaaaacag tgctatactg ctttaagtat aacactattt
     2821 ttattgtttt acgatgattt taatctgcta ttgaaagaaa gtcctgattg ctgattgagt
     2881 tgttaaacta atcttagtca gcccactatc catcatttat ttccttagct gattagtttt
     2941 cttctttttt gtttttcaaa cctagaccac cgagtaaacc tgcaagcgca agcccaagga
     3001 aaccaatact tgccattgat gtttgagtct caccagtatt tggtagcata gctttatcct
     3061 ctgacatcat cgtatcagac atcttgttag cagaagcagc catgttttca cctgccatcg
     3121 tgttggtaga acttgtcatg gtgtcagcag gcatgctatc tgtagtacct gtagcatgat
     3181 tgtgattcat cggagtcacg ccagaaccag agttagaagg tgataatgaa ccatttgctg
     3241 tgtctgatgt ttctttaaca tttatcttaa tagtgacttt tttagttgct acgatgttgt
     3301 ccaagtctgg tttaccgtct ttgttaccat agacattgac tgtagcgctg taagtttgag
     3361 taccgtttgc tcggaactgg tcaatgagcg cttgtttttc tttgccagct acatttccgt
     3421 ccaaggctac ttgatagaag tattgacctt tggtcttcac gttttcgcct agtggagata
     3481 gggctgggtt tttagcctca ccgttatctg accatggtgc cttgtcagat gccttgagca
     3541 agagacgagt caacatgcca tcacctgcga agagttcgta tggaatcaca tggttgacac
     3601 ctgctgtgaa tggaccttca cccttggctt tttctaagta ggctgctgga acatcgatac
     3661 tgtctttaac gttgtctgca acggcttttt gaactgtttc tttagaaatt aaaccgttta
     3721 tgttaatagt gactttttta gttgctacga tgttgtccaa gtctggttta ccgtctttgt
     3781 taccatagac attgactgta gcgctgtaag tttgagtacc atttgctcgg aactggtcaa
     3841 tgagcgcttg tttttctttg ccagctacat ttccgtccaa ggctacttga tagaagtatt
     3901 gacctttggt cttcacgttt tcacctagtg gagatagggc tgggttttta gcgtcgccgt
     3961 tatctgacca tggtgccttg tcagatgcct tgagcaagag acgagtcaac at
//
LOCUS       DAVLAQ010000097         3968 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000097 DAVLAQ010000000
VERSION     DAVLAQ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3968
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.097"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..568
                     /locus_tag="VXB71_001969"
                     /pseudo
     CDS             1..568
                     /locus_tag="VXB71_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1400..1759
                     /locus_tag="VXB71_001970"
     CDS             1400..1759
                     /locus_tag="VXB71_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452024.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            1769..2098
                     /locus_tag="VXB71_001971"
     CDS             1769..2098
                     /locus_tag="VXB71_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0452025.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            2121..3968
                     /locus_tag="VXB71_001972"
                     /pseudo
     CDS             2121..3968
                     /locus_tag="VXB71_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
BASE COUNT         1466 a          580 c          772 g         1150 t
ORIGIN      
        1 atcaaaaaat agttaactat attgctcatt tcaatagtta tgacattttg aaaaaaggtt
       61 ctcacttatc aggtgcatat aaacgaaaaa ttttttctaa agaaaataca cgattttgga
      121 gtttaatatt aactcgaaag aattttcgca acaacttgat attctctata aagaagttgg
      181 tgtattaagt ttgggacaaa aagttgtagc catgcttgat tttttattag catatagtga
      241 ttattctaaa gacttcagac cattgattat tgatcagcct gaagacaatc tagacaatcg
      301 ttatatttac aggcatttag ttcagcagtt tagagatgtg aaagctcaac gtcaaattat
      361 tttagcaaca cataatgcta caattgtaac aaattctatg acagatcaag ttgttattat
      421 ggagtcagat ggagttaacg gatggattga atcacaggga tatgttagtg aaaaatatat
      481 aaaaaatcat atcatcaatc aattagaggg aggaaaagat tccttcaagc ataaaatgtc
      541 tatatatgag acggctttat cagagtagag tcagaaaaag taggttagaa atttagccta
      601 cttttttctt tgtccgacag gcatagtgta catctgaggt ccaagtcctc tgtggatatt
      661 tgctgcagat gaaaccaata gcgactccta agcctgaata tcgtgaggta ggggggatag
      721 gaaggaatta gcgaaatcaa ggttctacaa acagaatcgt gacttgaagc catatatagc
      781 ggatgaggaa ctctaaaatc caaataggtg tcgtaaccta tatacgtaaa ttacgagagt
      841 aaactaggaa agatgtacgg cttattccgt gagcgtttag gacgtagtac aacgaatcat
      901 gggagtcagc tgaacacata gtattgaaga aatttctgta atggaaatgg agcgaagaag
      961 tgaacaatta aatgaatacc tctctaatta aatttgtcaa ttctaattcc tggtatgaaa
     1021 agacagtgac ctgaaaatgt aaacgatggg agctgatcat aaatatagga cggtacatgc
     1081 agtggtgtta gagattagtc cttacttgat ttgtgataac ttccccaaat ttcttctgct
     1141 atacttttct caacttttaa aaatccaact aagaatttta cctgggggtt tgggggcgga
     1201 gccactaagt tatcttatcg ttagctgtca aaactggtag gttttgatag gctggcgata
     1261 tgatttttgg gatattgtgg acacaatatc tgagctcgca aagaccgaac aaggagagac
     1321 tgaggtcttt aggaatcgta ctgacaatgt gaggcagcct tacattgtca gacaagtata
     1381 atgttgaaag aatggtaaga tgggacaaga aattaagtta atccgtaagc aatttagaat
     1441 cacgagacaa gaagaaaaac agataaaaga aatgatgagg gaacaaaaag tggatagttt
     1501 ctcagaattt cttcgtcaaa atttattgaa aaagaattat caggatagaa tttttgaaag
     1561 ttggttctcc ctttggcagt ctcaaaagtt tgaacagatt agtcgagatg tgtatgaagt
     1621 tctggttgtc gcaagagaaa atcatcaagt gactcaagag cacgtctcaa tcttattgac
     1681 ttgcgttcaa gaattgattg cagaagtgaa tcaagtacag ccactcagtc gtgagtttcg
     1741 tgaaaaatat atgggttagg aggatgtaat ggtttatcgc tatcgtacca atctcaaaaa
     1801 agtatttcta actgatccag aattacacca attgaatgaa cggattgcta agagcaattg
     1861 tcaaaatttt tcagtctatg ccagaaaagt tttgcttaat cccaatatgt catttgtcac
     1921 gattaacact gatacttatg accagttagt ttttgaattg agacgtattg gaaataacat
     1981 caatcaaatt gcgcgtgcga ttaatcaaag ccatctgatt tctcaggacc aattacaaga
     2041 attgagtaaa ggagtcggag agttaattaa ggaagtggac aaagaatttc aagtgtaggt
     2101 gaaaagactg aaggagtttc atggtagtta ctaaacactt tgcgacgcac ggaaaaaaat
     2161 atcgtaggcg tttgattaaa tatatcctca atccagataa aacagataat ctaaaattag
     2221 tatctgattt tggcatgagt aattacttag attttcctag ccatacagaa atggtagaaa
     2281 tgtacaatgt taactttact aataacgaca agttgtacga gtccagaaat gaccgacaag
     2341 aaaaacacca acaaactatt catgcccatc atctcatcca atcattttct cctgaagata
     2401 atctgacacc tgaagaaatt aaccgcattg gttatgagac catgatggaa ttgacaggag
     2461 gtcgttttaa gtttatcgta gcaactcaca cagacaaaga tcatgttcat aatcacatcc
     2521 taatcaacgc tattgaccgc aattcagata aaaagttgat atggaactat gccttggaac
     2581 gaaacctccg tatgatttca gaccgtattt ctaaaatggc tggtgcaaaa attattgaga
     2641 aacgttattc ttatcgaggt tataaaaaat atagggaatc tagtcataaa tttgaattga
     2701 aacaacgtct ttattttttg atgcagcaat ctaaatagtt tgatgatttt ttagagaaag
     2761 caaagcagtt gcatgttcag attgatttta gtcaaaagca tagtcgattc atgatgacgg
     2821 atcgagcaat gacaaaacct attcgaggac gccaactcag caaacgagat ctatatgatg
     2881 aagaattttt tagaacgcat tttgctaagc aagagattga aagtcgttta gaatttttgt
     2941 tgaaccgtgt caattcttta gaagagttaa taacaaaagc aaaagaattg aatctaacca
     3001 ttgacttaaa acaaaaaaat gtaactttta tcctgaaaga aaataatcaa aagataagtt
     3061 tgggtcatca aaaaataagt gataagaaat tatatgatgt caaatttttt caagattatt
     3121 ttaaaaataa ggaagtcatt gcttcagaag gattagagaa tttacaggaa cagtaccatg
     3181 ctttccaaga agaacgagat aaggataaag tatccactga agagattgag gaagccttta
     3241 agacatttaa gaagccttta agacatttaa ggaaaaatga gataccgttc gtgaatttga
     3301 agtggaactt gcagagaacc aaatagagaa gctagttgat aagggcgtct atatcaaggt
     3361 gtctttcggt gtcaaataga gcggtcttat tttcattccc aactatcaat tggatattat
     3421 ggaagaagaa aatcataaaa aatataaagt ctacattcga gaaacgtctt cttactttgt
     3481 ctataataaa gaaaacatgg ataataattg tttcatcaag ggtaggacct taatcagaca
     3541 attgagcaac gatagccaaa aactccccta tagacgacca actttaaaaa gtcttcaaga
     3601 gaagatttct gaaattaatc ttatgattga actatctaac acgaacaaac aataccaaga
     3661 aatcaaagat gagcttgtat tagaaattgc agagattgat atgaagctag aagaaaccca
     3721 agaaaaaatc gccaccttaa acaagatggc ggaagtcctt atcaatttga agagtgaaga
     3781 tgagatcggt agaaaattag ctaagtatga ttttgaccaa atgaacatga cggaatcaat
     3841 aatgttagat cgactcaata catatatttt aaaattacaa caggaactta gtaatgaaat
     3901 taataaatat gaggagatag ctagaagatt ggatttgttt gtgaaaatta ttaataccaa
     3961 taaattta
//
LOCUS       DAVLAQ010000098         3941 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000098 DAVLAQ010000000
VERSION     DAVLAQ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.098"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            217..480
                     /locus_tag="VXB71_001973"
     CDS             217..480
                     /locus_tag="VXB71_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0452026.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            486..2219
                     /gene="ptsP"
                     /locus_tag="VXB71_001974"
     CDS             486..2219
                     /gene="ptsP"
                     /locus_tag="VXB71_001974"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0452027.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            2474..>3941
                     /locus_tag="VXB71_001975"
     CDS             2474..>3941
                     /locus_tag="VXB71_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0452028.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         1305 a          770 c          840 g         1026 t
ORIGIN      
        1 tgaaatagca atgattatcc tataaattgt ttttgaagaa actatatcct gtgttttgtt
       61 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
      121 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
      181 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
      241 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
      301 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
      361 ggtgttatga gtcttggtgt tggtcaaggt gctgacgtaa ctatctcagc tgaaggtgca
      421 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
      481 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
      541 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
      601 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
      661 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
      721 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
      781 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
      841 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
      901 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctatcaat gaagaagtga
      961 ttgtgattgc gcatgacttg actccttcag atacagctca attggacaaa aactttgtaa
     1021 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
     1081 ttgaaattgc tgctgtatta ggtacaaaca acatcactga aatcgttaaa gacggtgaca
     1141 tccttgctgt taacgggatc actggagaag tgattatcaa cccgacagat gaacaagcgg
     1201 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
     1261 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
     1321 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
     1381 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
     1441 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
     1501 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
     1561 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
     1621 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
     1681 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
     1741 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
     1801 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
     1861 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
     1921 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
     1981 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
     2041 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
     2101 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
     2161 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
     2221 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
     2281 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
     2341 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
     2401 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
     2461 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
     2521 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
     2581 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
     2641 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
     2701 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
     2761 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
     2821 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
     2881 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaagaaatca atcggcaaaa
     2941 acaagaacat agtcagcatc gtgaaggagg gacttcaaca aacgatggtg cggtagcctt
     3001 tgcacgttca caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
     3061 cattgaggac acgggtgatg cttatatcgt tcctcacggc gaccattacc attacattcc
     3121 taagaatgag ttatcagcta gcgagttagc tgctgcagaa gccttcctat ctggtcgggg
     3181 aaatctgtca aattcaagaa cctatcgccg acaaaatagc gataacactt caagaacaaa
     3241 ctggctacct tctgtaagca atccaggaac tacaaatact aacacaagca acaacagcaa
     3301 cactaacagt caagcaagtc aaagtaatga cattgatagt ctcttgaaac agctctacaa
     3361 actgcctttg agtcaacgcc atgtagaatc tgatggcctt gttttcgacc cagcgcaaat
     3421 cacaagtcga accgccagag gtgtagctgt ccctcatggt aaccattacc actttatccc
     3481 ttatgaacaa atgtctgaat tggaaaaacg aattgctcgt attattcccc ttcgttatcg
     3541 ttcaaaccat tgggtaccag attcaagacc agaacaacca agtccacaat cgactccgga
     3601 acctagtcca agtctgcaac ctgcaccaaa tcctcaacca gctccaagca atccaattga
     3661 tgagaaattg gtcaaagaag ctgttcgaaa agtaggcgat ggttatgtct ttgaggagaa
     3721 tggagtttct cgttatatcc cagccaagga tctttcagca gaaacagcag caggcattga
     3781 tagcaaactg gccaagcagg aaagtttatc gcataagcta ggagctaaga aaactgacct
     3841 cccatctagt gatagagaat tttacaataa gacttatgac ttactagcaa gaattcacca
     3901 agatttactt gataataaag gtcgacaagt tgattttgag g
//
LOCUS       DAVLAQ010000099         3826 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000099 DAVLAQ010000000
VERSION     DAVLAQ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.099"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(134..802)
                     /locus_tag="VXB71_001976"
     CDS             complement(134..802)
                     /locus_tag="VXB71_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0452029.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFANKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLIIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(913..1704)
                     /locus_tag="VXB71_001977"
     CDS             complement(913..1704)
                     /locus_tag="VXB71_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0452030.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSILFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(2129..2893)
                     /locus_tag="VXB71_001978"
     CDS             complement(2129..2893)
                     /locus_tag="VXB71_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0452031.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(2886..3656)
                     /locus_tag="VXB71_001979"
     CDS             complement(2886..3656)
                     /locus_tag="VXB71_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452032.1"
                     /translation="MLYLLGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDFLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
BASE COUNT         1328 a          815 c          636 g         1047 t
ORIGIN      
        1 agatgaaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga cgtggtttga
       61 agagattttc gaagagtatc atacgaaaaa gccctgttcc tcaagatgag gagcaaggct
      121 ttttgagttt caattattct tctgttccaa ggaaattttt tgcaacaagg gctgcaagaa
      181 ctccaccagc gattggtgca aggatgaaaa tccaaacttg ttgaagggct gcgccgccta
      241 ccaagacagc tggtgccaag ctacgagctg ggtttactga aagtccagta atcttcagtc
      301 cgacaagaat catcgccatc aatgacaaac cgattaccaa accagcaatc gcgccattgc
      361 ccttactttc tgaagtcaca gtcatgataa tcaagacaaa caagaaagtt gcgatgactt
      421 caaacaagaa accaccaaag acagtgacac cgtttgccaa ggcattttca ccaagactag
      481 cagttgacat acctgaatta cccaagagga agaagactgc gccagaagcg atgaaagctc
      541 caacaacctg accaaggatg tagtttacaa gttctgaaga tgacaaacgt ttgtttgcaa
      601 acatagcaat cgaaacagcc gggttcaagt gagcacctga aacagttccg attgagtagg
      661 ctgccaccac gattgccaaa ccaaaggcaa aggcgattcc aaggtgacca aggccatcaa
      721 gaccatttcc aaaaacaaca gctcctgtcc caacgaacac aagcatgaac gtaccgatta
      781 actcagcaac aaattttttc attttctttc tccttttttc aaaaactaga tactagtcta
      841 tcaaaagtag gaaagggttt caagaaaatt gattggaaat tttttgaaaa tcatagaact
      901 attagctaat ccctagtatt gaaaagactg gatagcttct ttcaggtcat cttgtaaact
      961 atttctctgg tcaagttgga catagacttc caccagacag gatctaaagt tggaaaattt
     1021 gtaaaaatcc tccctttctt ctatcggaaa atcaacagtt tttatccaag aagctacttg
     1081 ttcttgctcc aacttccctt gtaaaatagg ttcatagatc actcttgcta aacgccaatc
     1141 ctcatcatct gtaaagagaa tcgacattct tttaaatagt tggccaagta tatcaaatac
     1201 ttcatgaatt ctgtttatag gaaagtctgg atgacagacc acctctgtca gtaaatcggc
     1261 tccatgtgca aaagaatgaa cccaaccata ctgacttgag aaacctgttg tatccttttc
     1321 ttttgaaaga tagtgcaagc cttgatttaa aaggacatta cgaatttctg attgtaatcc
     1381 ctgataaaaa accgattgct ggttagcatc tgcagacaag agatttgcat aaataagtgc
     1441 cctaaaagaa cgttcaagtg ttgacaagcc taccttatca atctctttat ctaaccctcc
     1501 atcagctaag accacctcag caatgaaatg aaattgttcc tgtgtaaata gctcttcctg
     1561 aatctcctta gcaaagcttg taaaaacaag gtcatcacga atttctggag aaggatttcc
     1621 caaatgatca aacaaccact ggatttcttc ctggttataa tttggttttt cttctgctat
     1681 ttttcttagt aaatcttgat acatggtcaa tacctctaca tttctagcaa ctgttcaaaa
     1741 aggcagtctt aaatgacttt accaatttgt aaaattaagt taaaaagaaa aagacattta
     1801 tattcagaga aacagcatat ttctgaaaag atatataaat gatttattcc atatgaccac
     1861 aaatgaactt gtaatgatag agccttatca caaaaatcac attcctgtct caaaaattgc
     1921 gaaaaactag ttataataaa gtgaaataaa aactatacaa attgattagg gaatttaaaa
     1981 caatttctaa caatatttta aaaactgaac cgtactattt caacttccat aaattacaat
     2041 attgataggc acagttccca tacctgtcca aattcgaata acgtttagta taaattagaa
     2101 tatgactaca acatcacaaa taattagact atctataata tctacgatgt aacatataca
     2161 taggaagcac cgttatcaag agcgccaagg ctatcaacca gataagatga agatacaaac
     2221 ctgtcacctc acctccccat ataatacgaa tcatgcgggt agcgtgatac aagggagaaa
     2281 accaagtcaa atcaccaagt attgggggca aggaagtaat gggaaagaag gtatctgaaa
     2341 acatataaag aggacggatt accaaaacat tgtagtaatt cagaaattcc ctagacggcg
     2401 ccaagtaggt aaagattagt cccaaaacac caaacaaata acccactata aataaaatca
     2461 gaggaatcaa taacatcaag acatgaaaat gcgctgtgat aagcatggaa atcagccaaa
     2521 aaatcccacc gaaaatcact gcacgaatac ctgcccagat agcctgaccc accacaatat
     2581 cattcgtatt gattggcgtc atcaacatag catcataagt cttttcaatc ttatactgga
     2641 taaaggcatt gaccgttgtt tctgcagtgg ccgcagacat ggcagtcgca gcaattaaac
     2701 ctgtaatgac aaaatcacgg tagagcatac cgttaacatg cgtcaaataa gcaccaactc
     2761 caaatcccat tgctaaaaga taaaagaggg ggtcgataag gttggggaca attgaaattt
     2821 taaataaatt tctaaaactc atgtagttgc gtaccacaac gtgtccgatg gagtgaaatg
     2881 ataacttaaa catgcaagtc ctccttctct gtcccagtca accccaaaaa aagcgtctca
     2941 aggttgtcag catcatactt gatgagcaag tcttctacag ttccttcttc tttgatagtc
     3001 ccttggtgga gcatcagcac cctatctgtc aaatattcaa tctcattcat atagtgggaa
     3061 gtaataatga tggaaacacc taattccttc aactccaaaa gtttatccca aataatattg
     3121 cgggattgaa tgtctaaacc aactgtcggt tcatctaaaa tgataatatc aggccgattg
     3181 atgagagctc ttgccaagac aagacgtcgt cgcatcccac ccgacagctg attcaccatc
     3241 ttttgcgcat gtttgctcag ttgaacaaaa tccaagagaa aatcgattct cttcctaagt
     3301 tcgacagatg agataccata acatagaccg tgagcaaaaa gattatcata aacattcaag
     3361 gtcatatcca gcatatcctc ctgccctaca atacccagac aagatttact cttacgacga
     3421 ttggtttcaa tattttgccc caagatatca atctctcctg aggaaattga ggtcagtgag
     3481 taaatcatct ttaaagtgga tgttttgcca gcaccgttga ttcccaagat acccaaacac
     3541 tctccttctc ccaattcaaa gctaattccc ttgacagctt cataagaacc atattgcttt
     3601 tttagatttt taacacttaa cttcttcact ctttctttcc ccaacaaata gagcatgttg
     3661 gatactttgt taattcatct cacttttgaa aaaatgttga gaatgtaatc ttaagattaa
     3721 cgtccttcaa ctgtggatac tgctgcaatt acttttgtaa ttttacctcc atttaaactc
     3781 agacaataaa atttaaaata ttctctagta aaacattttt aaaatc
//
LOCUS       DAVLAQ010000100         3793 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000100 DAVLAQ010000000
VERSION     DAVLAQ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.100"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            371..598
                     /locus_tag="VXB71_001980"
     CDS             371..598
                     /locus_tag="VXB71_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452033.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3672
                     /gene="nanA"
                     /locus_tag="VXB71_001981"
                     /pseudo
     CDS             886..3672
                     /gene="nanA"
                     /locus_tag="VXB71_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
BASE COUNT         1289 a          633 c          839 g         1032 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacgctt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataggctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gggagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaatttc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacggtaa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgcca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gttattggct tggagtttga ctcagaagta
     3301 ttggtcaaca aggctccaac ccttcaattg gcaaatggta aaacagcgac tttcctaacc
     3361 cagtatgata gcaagacctt gttgtttgca gtagataagg aagatatcgg acagaaaatt
     3421 attggtatag ctaaaggaag catcgaaagt atgcataatc ttcctgtaaa tctagcaggt
     3481 gccagagttc ctggcggagt aaatggtagc aaagcagcgg tgcatgaagt tccagaattt
     3541 acagggggag ttaatggtac agagccagct gttcatgaaa tcgcagagta taagggatct
     3601 gattcgcttg taactcttac tacaaaagaa gattatactt acaaagctcc tcttgctcag
     3661 caggcacttc ctgttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3721 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3781 atcaggaaag tca
//
LOCUS       DAVLAQ010000101         3787 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000101 DAVLAQ010000000
VERSION     DAVLAQ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.101"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(173..1588)
                     /locus_tag="VXB71_001982"
     CDS             complement(173..1588)
                     /locus_tag="VXB71_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0452034.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VXB71_001983"
     CDS             complement(1601..3439)
                     /locus_tag="VXB71_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0452035.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..3759)
                     /locus_tag="VXB71_001984"
     CDS             complement(3457..3759)
                     /locus_tag="VXB71_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0452036.1"
                     /translation="MGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVENTTYCD
                     DDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTKNLD"
BASE COUNT         1274 a          766 c          496 g         1251 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggcacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacac catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tgtcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaatgattac caagactttc aacatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactct
//
LOCUS       DAVLAQ010000102         3740 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000102 DAVLAQ010000000
VERSION     DAVLAQ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.102"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            27..641
                     /locus_tag="VXB71_001985"
     CDS             27..641
                     /locus_tag="VXB71_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452037.1"
                     /translation="MKLKKTCVFQNLNFSCKQGEIIGITGANGSGKSVLFKLIAGLYS
                     PSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLASIRGVVGNQEIN
                     DTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMNALDKSSVENMR
                     TLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(721..1582)
                     /locus_tag="VXB71_001986"
                     /pseudo
     CDS             complement(721..1582)
                     /locus_tag="VXB71_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(1594..2352)
                     /locus_tag="VXB71_001987"
     CDS             complement(1594..2352)
                     /locus_tag="VXB71_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0452038.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(2353..3030)
                     /locus_tag="VXB71_001988"
     CDS             complement(2353..3030)
                     /locus_tag="VXB71_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0452039.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(2990..3658)
                     /locus_tag="VXB71_001989"
     CDS             complement(2990..3658)
                     /locus_tag="VXB71_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0452040.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
BASE COUNT         1149 a          685 c          824 g         1082 t
ORIGIN      
        1 aaataatcat attaaaaaat attgagttga aattaaaaaa aacatgtgtt tttcaaaacc
       61 ttaattttag ttgtaaacag ggggaaatta taggaattac tggtgcgaat ggctcaggga
      121 aaagtgtatt gtttaaatta atagctggtt tatatagtcc gtcttatgga gaagtgttaa
      181 tcaatgggga aaatattgtt cctgagagaa aaattccagc taatttggga gctttgattg
      241 aagaacctgg ttttataaat tattatagtg gctttaagaa tttacaatat ttggcaagca
      301 tacgaggagt agttggtaat caggaaatca atgatacact gaaaatagtt ggtctatatg
      361 agcaaaaaga ccagaaagtt aaaacttatt cgctaggtat gaggaaaaag ctagggattg
      421 ctcaagcaat tatggagaat ccctctattc ttttactaga tgaacctatg aatgccttgg
      481 ataaatcaag tgtagaaaat atgagaacat tgtttagaaa gctctctagt gaaaaaggga
      541 caacaatttt gattgctagt catagtgaag aggatattcg tatcttatgt gataaagtat
      601 atgcaataga agataaagta tgtacactgt gttcagattg aacatcttag atagactcag
      661 gatgttatag gtaaaatctt aaaaagggat tggagcttaa aatccagtcc cttttaagag
      721 ttaatggcca ccttcaacaa ccaggtcatc tgctttagca gcgtcaccgt aggttgggtg
      781 aagtgttttt tcataggcct tgtggaagaa gttttccttg cctaattttt caatatcttt
      841 attgatgaag tctagcaatt cttggttgcc tttttgaact gctgccgcaa tggtatcggg
      901 atcaccgagg gaagtaattc ctacttcaaa tcctttattt tcaagcgccc aagctagaac
      961 ttccgtattg tcagttgaaa aggcatctcc acgtccgtca agaagagctt ggtaagagtc
     1021 actgtattgg tcgtattttt ggagtttgat ttctggatga ttcttttcaa aataagtctc
     1081 agcagtcgtt ccttttgtga caattaaggt tttaccttca agttgtttga cgtctgtaat
     1141 gagaccagtc ttaggtgata cgacacccag agaaactttc atatatggaa gggcaaaatc
     1201 aacttgtttc ttacgttcgt cagttactgt aaagttagca agagtaatat ctaccttgtt
     1261 tgaaatcaag tattccgcac ggttggcagc atcgactgaa atgtatttaa ccttgacacc
     1321 aaggtcttta gctagttggt tccctagttc aatatcgtag ccttggtaag aaccatcatt
     1381 gtcaacgtag ccaaacggtt ttttatctcc aaacacggcg attcgcagtt caccgccttt
     1441 ttttgatttc atcgatagtg cgagctttgg cagttgtttt tccagaggat gaaccagcgt
     1501 ttccacctga gctacaagca gtgataaaga taagggcaaa ggcaagtgct aaaacagtta
     1561 agagtggttt gaatagtttc ataagaatct cctttataga tatgagccaa attggctaaa
     1621 gtcaaagacg tttaaaaatt cctgggctcg tttggtttgc ggattggtaa agaaggcttg
     1681 agctgttcct tcttcagcga ttttcccttg gtcgaggaag ataatccggt cagcaatggc
     1741 ttgggcaaac tgcatttcgt gggttactaa aatcatggta cggccttctt gggccaaatc
     1801 attgataagt tccagcacct cacgcaccat ttctggatcc agcgaagcag tcacctcgtc
     1861 aaaaaggatg atttctggat gcattaggag ggcacggaca attgcaacac gttgcttctg
     1921 tccaccagat aattgacggg caaagctatg ttgtttatcc agcaaaccga cacgatctag
     1981 taattgcaaa gcttcttccg ttacttcttt cttgtccctt ccttgagttt tgatagggcc
     2041 taggatgagg ttttgtaaga catccagatg gggaaagagt tcataacttt gaaagaccat
     2101 gccaatcttt tggcgaacta ggtgaaaatt ttttttattt tcaacgatag actgaccatc
     2161 cagaaaaata tctccacctt gaatactttc taagccgttg aggcaacgaa ggagggtact
     2221 tttcccacaa ccagatggcc ctaggatgac aacaacttcc ccttttttga tttctagaga
     2281 aagtccttgg aggatgggat tgtctccgaa ggattttttt agttccttga tttctaagat
     2341 agtttcagac atttagtttc tccaatgttt ttctaagtga gtggatagtt tggaaatagg
     2401 gtagcaaact gcgaaatata agactagaat ggttccataa atccaaaatg aagcagttgg
     2461 gatggtcagg cgattgctat cgatgatttg ttgtccaact ttggtcactt ccacaacccc
     2521 aatcaaaaca actaatgaag tggttttaat catccgagtg acaagattga tagcctgcgg
     2581 tagcagtctt ctcaagactt gtgggatgat gatgtggtag taaagttgaa cattagtcaa
     2641 gccgagtgcc tgtccacttt caaactgatg tttagggaga gaagtgatag ctccacgtac
     2701 caagtctccc atttcagctg ttccccagag ggtaaaaacg ataatagctg aagtctcacc
     2761 tgagatattg atattaaagt ttcgagccaa gccaaagtaa acgatgaaga gtagcaccag
     2821 ctggggcatg atacggataa attccagata caatcgtgtt aaaaatcgta tgattctaga
     2881 atgggaggtc atgatgattc ccatgactgt tccgaacatc atggataaga ggacagacag
     2941 gatggatatc ccaatcgtaa cgcccaatcc ctgtaagatt ctcaggagat tatttccttg
     3001 aaagagtact tggattcccg aatcctgcat ggcggagcct cctttctatc cagctaaaga
     3061 ccagtgagat gggtagcagc atgatcagat aagcaactac caacatagct agcgcaatgt
     3121 ctgtctcata gtagagacca atcaaatcct tggcgacgta catgaggtcg gccaaagcca
     3181 ctgctgagaa aacagaggtt tccttgataa ggaaaatgac attggcacta aaggagggga
     3241 gtgccaccgc tgttgcttgc ggaagaacca catagtaaaa gacctgtaga ggtgtcagac
     3301 caatagcgag gccaatctcc tgctgggttt gactgatggc ttccagcccg cttcggaaag
     3361 attctgccat ataggagtct cctaaaaaga caagcccaag cgttgcacag acttctgaag
     3421 ataggacaat cccgattcgg ggaagaccga agtagagaaa gaagagttga atcaaaaggg
     3481 gcgtattacg tgacaattca atgtaggctg tcgctacttg cgacaaaaca aggattcgat
     3541 aatgtcggat gatactaacg attaaaccga gcagaaagga tcccaaaatt ccccaaactg
     3601 caatatgcaa ggtcagaaag aatgcctttt gatatagtgg tagatattgt tcaacaatgg
     3661 atcaatccaa aaatagaacc tcccatctag aaataataca gttattgtag cacttaaaat
     3721 cttctttgga taatatctat
//
LOCUS       DAVLAQ010000103         3489 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000103 DAVLAQ010000000
VERSION     DAVLAQ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.103"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(94..1380)
                     /locus_tag="VXB71_001990"
     CDS             complement(94..1380)
                     /locus_tag="VXB71_001990"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0452041.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(1611..1847)
                     /locus_tag="VXB71_001991"
     CDS             complement(1611..1847)
                     /locus_tag="VXB71_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0452042.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            2113..2910
                     /locus_tag="VXB71_001992"
                     /pseudo
     CDS             2113..2910
                     /locus_tag="VXB71_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2945..3489)
                     /locus_tag="VXB71_001993"
                     /pseudo
     CDS             complement(2945..3489)
                     /locus_tag="VXB71_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1189 a          749 c          510 g         1041 t
ORIGIN      
        1 aaagtttagg atatttgtta caacaagtta ggaggtcttc ttgtaactgt ctatagtata
       61 cccgacctat cttaaacaaa tcttaaaaat ctcttaggac caaacacttt ctaaaatatt
      121 tgtttgttca cgaccaggac ctactgagaa agtagaaata cgaacgccaa ccaattcact
      181 cacacgacga acatagttac gcgcattctc aggaagatct tccaaattgc gaactccggt
      241 aatatcttct gaccaacctg gcaactcttc atagataggc ttgcaacgtt tcaattgctc
      301 aagactagct ggatagtagt caatacgttg accgtcaaga tcataggcca cacagatttt
      361 cacagtatcc aaaccgctca aaacatcaat agagttcaaa gaaaggttag taataccaga
      421 aacacgacgg ctatgacgca tcacaactga gtcaaaccaa cctacacgac gtggacgacc
      481 agttgttgta ccatactcat gacccacttc acggatacgt tctcccactt catcaaacaa
      541 ctcagttggg aaaggaccat ctcctacacg actcgtataa gctttacata cacctacaac
      601 cttgtcaatc ttgcttggac cgacaccaga accaattgtc acaccaccag ctacagggtt
      661 tgatgacgta acaaatggat aagtaccttg gtcgatatct agcataacac cttgtgcacc
      721 ttcaaaaagc acacgtttgc cattatcaag cgcatcattc aagataacag atgtatctat
      781 cacgtatttc ttgatttgtt gaccatattc gtaatattct tcaaaaatat catcgaaaac
      841 aatcgcttta ctgtcataca atttttcaaa aagacgattc ttttcagcaa ggttacgttc
      901 taaacgctca cggaaaatat ctttatctaa aagatctgca atacgaattc caacacgagc
      961 agccttgtcc atataagctg gaccaattcc cttaattgtc gtaccaatct tattgtcgcc
     1021 cttagcttct tcttgcaagc gatccaactc gatatgataa ggcaaaataa catgcgcacg
     1081 atcagaaata cgcaagttat cagttgttac accttcctca tgaagatagc tcaactcttt
     1141 tacaagagat ttaggattta caaccatacc attcccaatg acagatattt tttcagggaa
     1201 gaaaatccca gatggaatca agtgcaactt aaatttctta ccgtcaatca caatcgtgtg
     1261 accagcatta tcaccacctt ggtaacgtgc aatcacttct gcattcgctg aaaggaagtc
     1321 tgtaatcttc cctttacctt catcacccca ttgggtacct acaacaacaa ctgaagtcat
     1381 aattttgtct gagccctcag gctcttcctt tctcacatac atggcaggac tctcacctgc
     1441 aattatatct tacaatttat tataataaaa aatcgccttt ttatcaagaa gaaacaatag
     1501 aaagatttgc tatttccaac tattaaaaaa tgatttagaa aaattactag ctatttacta
     1561 ttatctttac ataaaagagt aaattagttc ggaaatttac taaaattacc tcaacaagaa
     1621 ataaaacccc gattcattac caatttttca agatacaaac gataagcaac acgataatgg
     1681 taaacgataa aatccctatg acaaccaatg ccatatctca ctaaataata aattaaaaat
     1741 ttaaaatgaa catgttccca gtcaaaatta tcaccaaatg taggaccata ctcttcttca
     1801 atactatcat agaaattagc catctgctca taaatttttt gtaacataat caaatactcc
     1861 ttttcttttt tataaactta ttctaacaaa aaattttaca cattcactat caattcctga
     1921 attgttaaaa taccagcctc aacaagataa aaataggaaa agttgacaaa atagaaacaa
     1981 atttgctacc taaatttcaa acaattaaag ttctaaaaag accgccttaa aacttttggg
     2041 taaatcctat tagaactata atatttttat ataggtatta tggttctgat tttctagtat
     2101 aaaaaaattc aaactagaat tcttcttaga aaaggccgtt ttaagtgcta tcattgctca
     2161 aaaatggagc tcgctgagac ttctatcgtc aagaagaatc atcaaattcc ttgtatcatc
     2221 aaccaaaaga ttgctcaaaa gttaattgaa aagatttcta tgaccgacat tgatcatcag
     2281 ttgtctattt caacttcaac tgtcattcgc aagatcaata attttcactt tgagcatgat
     2341 ttttcgcgtc ttcctgagat tatgtcctag gacgttgaaa cagtccgggg agtgactgtt
     2401 tcaatcggga gatggagatg agctttattg ctcaggactt tgataaactc aatatcataa
     2461 ctgttcttga gagcagaaca caagccatca tccgaaatcc catgaataca aggctatcaa
     2521 gcgctactgg aagctcattc aacaagatag tcagaaactg agtgataaac gattttatcg
     2581 ccctactttt cgtatgcact tgactaataa agaaattcta gataaacttt tgagctattc
     2641 cgaagacttg aaacaccact ataatctcta tcagctcttg cttttccacc tctgtttcag
     2701 actttgttta aaaccttcct caaagataaa gagaaaatcg tcaacgccct tcaattacct
     2761 tattccaacg ccaaactgga agccaccaat aatctcatca aacttatcaa gcacaatgcc
     2821 tttggtttta ggaactttga aaacttcaaa aaagaaagga cgaaatttgt cctttctaga
     2881 tcttcgcttt cttcaaccca ctacagttga caaagaaccg aaaaatgtct cgcctctaat
     2941 atagtcaatt gaaacaagaa caagagaaaa gagcctcgta aaaggtattg caacttggta
     3001 ataccttttt gaggttcttt ttgatataag cccatgtttt ctcaatagga ttgtactcag
     3061 gtgagtaggg aggaagaggt aaaagtttat gcccaaactc ctcgcataaa agttctaact
     3121 tacccattct atggaatctt gcattatcca taataataac cgatggtgtg gttaatgttg
     3181 gtaagagaaa cttctgaaac caagcttcaa aaaagtcgct cgtcaccatc tcttcgtaag
     3241 tcattggagc gattaactca ccatttgtta gacctgcaac caaagaaatc ctctgatatc
     3301 ttcttccaga tactttacct cttattaact gaccttttaa tgagcgacca tattctcgat
     3361 aaaaataagt atcgaatcct gtttcatcaa tctaaacagg tgctaggtgc tttaaactat
     3421 taaaattttt aagaaataag gctacttttt ctgggtcttg ttcatagtag gtgtggttct
     3481 ttttttcga
//
LOCUS       DAVLAQ010000104         3389 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000104 DAVLAQ010000000
VERSION     DAVLAQ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.104"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            147..1349
                     /locus_tag="VXB71_001994"
     CDS             147..1349
                     /locus_tag="VXB71_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0452043.1"
                     /translation="MKILFVNMFYNEAGGAQKSTKFLAEQLVKEGHEVFAYSDDAIDS
                     DIDEVINRVKIFRRRTPLFSLHYIFSAKKNPAKHFFYKIFETYNVFAKRKFINIIEEV
                     QPDIVHFNTISGMSLSIVKEAKKRNIRTVWTLRDYWLEYPWGEKDISLIKLLNRIYRP
                     FVKKSLRHLDIVTAPSAFTLNNFINKGFINPSSQKCMVIENAVIFSKGKLENIIKQKQ
                     ETKRNPEKTNFLFVGSILEIKGVFNLVKAFKKLTSPEISLKIVGKGKDLEKLQKEIES
                     DPRIQYLGFQDTETLYKTYQNSDVLVVPSAWDEPFGRVVIEGNANGLPVITSDRGGLP
                     EIVQTVGGGEIFTDESGNTLYSLLKKFVEMENYNVYYQCILENIDIYSIEKQSEKFTN
                     LYLDKEIE"
     gene            1383..2615
                     /locus_tag="VXB71_001995"
     CDS             1383..2615
                     /locus_tag="VXB71_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0452044.1"
                     /translation="MKIAVAGTGYVGLSIAVLLAQHHEIKAVDIVAEKVELINQKKSP
                     IQDDYIEKYLVEKDLNLEATMDAKYAYEDAEFVVVAAPTNYDSKKNFFDTSAVEAVIQ
                     QVKKINPKAVIIIKSTIPVGFTESVQKKYQYKNILFSPEFLRESKALYDNLYPSRIIV
                     GTDLEDTYLKDKANIFASLLKEGAIKEDIDTLFMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDAKAIIDGIGLDPRIGNHYNNPSFGYGGYCLPKDSKQLLANYFDVPQ
                     NMMTATVESNRTRKDFIAQRILEKAGVSETDSLDAFKNIQDIVIGIYRLTMKSNSDNF
                     RHSSIQGVMKRLKAKGVTVIIYEPTLKDGETFFGNKVVNNLDKFKEASNVIVANRFEP
                     SLEDVSNKVYSRDIFKRD"
     gene            2834..3389
                     /locus_tag="VXB71_001996"
                     /pseudo
     CDS             2834..3389
                     /locus_tag="VXB71_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1212 a          471 c          647 g         1059 t
ORIGIN      
        1 tgtttatctc ggattttgta aacgacctta ttttacattt atcagttcag tttgttattt
       61 tatttttaat atggggaatt gggatgtata ttagcggaga gtatcgacga gtcttcgcgg
      121 ttataagaaa ataaaggagc aattttgtga aaattttatt tgtgaatatg ttttataatg
      181 aagcaggagg tgcacaaaag agcaccaaat ttctagctga acaacttgta aaagaaggac
      241 atgaggtatt tgcatactct gatgatgcca ttgattcaga tattgatgaa gttattaata
      301 gggttaagat ttttagaaga agaaccccgc tttttagtct tcactatatt ttcagtgcta
      361 agaagaatcc agctaaacat tttttctata aaatatttga aacctataat gtatttgcga
      421 aaagaaaatt tatcaatatc attgaggaag tacaaccaga tattgttcac tttaatacaa
      481 tttcaggaat gtctttatca atagttaaag aagctaaaaa gagaaatatc aggaccgttt
      541 ggaccttgcg agactattgg ctagaatatc catggggtga gaaagatatt tctcttatca
      601 aacttctaaa tagaatatat agaccttttg ttaagaaaag tttaagacac ttagacatag
      661 taacagcacc atcagcattt actttgaata attttatcaa taaaggattt attaacccat
      721 cttctcaaaa atgtatggtc attgaaaatg ctgttatatt ttcaaagggt aagttggaaa
      781 atattatcaa acaaaagcaa gaaacaaaaa gaaatccaga aaaaacgaat tttctttttg
      841 taggttctat acttgaaata aagggcgttt ttaacttagt aaaggccttt aaaaaactaa
      901 ctagtccgga aatttctttg aaaattgtag gaaaaggaaa agatttagaa aaacttcaaa
      961 aagaaattga gagtgatcct agaatacaat atttaggctt tcaagataca gaaaccctct
     1021 ataaaactta tcaaaattcg gatgtattgg tcgtcccatc tgcttgggat gaaccgtttg
     1081 gtagagttgt aattgaagga aatgcaaatg gccttcctgt catcacttca gatagaggtg
     1141 gattacctga aattgtgcaa acagtaggag gaggagaaat ttttacagat gaatcgggaa
     1201 atacattata tagtctttta aagaaatttg tagaaatgga aaactacaat gtctattacc
     1261 aatgcattct tgagaatatt gatatttatt ctatcgaaaa acaaagtgaa aagttcacta
     1321 atctgtattt agataaagaa atcgaataat aagttgtttt tgtagcagta acggaggtaa
     1381 ttatgaaaat agcggtagca ggaacaggtt atgtaggatt atcaattgct gtgttgttgg
     1441 cacaacatca cgaaataaaa gcagttgata ttgttgctga aaaagttgaa ttaatcaatc
     1501 aaaaaaagtc tccaattcag gatgattata ttgaaaaata tttagtggaa aaagatttaa
     1561 atttggaagc aactatggat gctaagtatg cttatgaaga tgcagaattt gttgttgttg
     1621 cagcaccaac aaattatgat tcgaaaaaga acttttttga tacatcagca gtagaggcgg
     1681 tcattcaaca agtaaaaaaa attaatccca aagcggtaat aattattaaa tctacaatcc
     1741 ctgttggatt cacagagtcc gttcaaaaga aatatcagta taaaaatatc ttatttagtc
     1801 cagaattttt acgcgaatct aaagcattat acgataacct gtatccaagt cgcatcattg
     1861 ttggaactga cttagaagat acttatttaa aagacaaagc taatatattt gcttccctac
     1921 taaaagaggg ggctattaaa gaagacatag atacactttt catgggagta acggaagctg
     1981 aggcagttaa attatttgcc aatacctacc ttgcgttgcg tgtttcttac tttaatgaat
     2041 tggatactta tgcagaggtg aaaggtttgg atgcaaaagc cattattgat ggtattggcc
     2101 tagatccacg tataggaaat cattataaca atccatcctt tggctacggt gggtattgtt
     2161 tacctaaaga tagtaagcag ttattagcaa attactttga tgtaccacaa aatatgatga
     2221 cagcaactgt tgaaagcaat cgaacgcgta aggattttat cgctcaacgg attttagaaa
     2281 aagctggagt atctgagact gatagtttag atgcgtttaa gaacatacaa gatattgtta
     2341 taggtattta tcgtttaaca atgaaaagta attcggataa cttccgtcac tcctctattc
     2401 aaggcgttat gaaacgattg aaagctaagg gagttacggt tatcatctat gagccaactt
     2461 tgaaggacgg ggaaacattc tttggtaata aagtggtaaa taatctagat aaatttaaag
     2521 aagctagtaa tgttattgta gccaatcgtt ttgaaccttc actagaggat gtgtctaata
     2581 aagtttatag tcgagatata tttaagcgtg actaataaat acgtccacgt gacgtaatat
     2641 ctattaaatg aataaaatat taataaacat ggcatcgata tcttttttgg acttgaattg
     2701 tcaaattaag tgcacatttt tttcatagaa aacttcataa ggtgttttcc ggttaagaca
     2761 ttttcgtggt ctattatcta agttggttta tataatagac ttcctgcgaa acaaaatatg
     2821 gtataatagt tctatgaatt atgaagcaag taaacaacta accgatgtac gatttaagcg
     2881 tcttgttggt gttcaacgca cgacttttga agagatgtta gctgtattaa aaacagctta
     2941 tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta agcctagaag actttcttat
     3001 ggcgactctt caataagtgc gagaataccg cacttatgaa caaattgcgg ctgattttgg
     3061 tattcacgaa agcaacttaa tccgtcggag ctaatgggtt gaagtaactc ttgttcaaag
     3121 gtggtgttac gatttcaaga actcctctca gttctgagga cacggtaatg attgatgcga
     3181 cggaagtaaa aatcaatcgc cctaaaaaaa gaattagcga attattctgg taaaaagaaa
     3241 tttcacgcta tgaagactca agcgattgtc acaagtcaag ggagaattgt ttctttggat
     3301 atcactgtga actattgtca tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga
     3361 caagctggta aaatcttggc tgacagtgg
//
LOCUS       DAVLAQ010000105         3348 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000105 DAVLAQ010000000
VERSION     DAVLAQ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.105"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            480..1766
                     /locus_tag="VXB71_001997"
     CDS             480..1766
                     /locus_tag="VXB71_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0452045.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1781..2092
                     /locus_tag="VXB71_001998"
     CDS             1781..2092
                     /locus_tag="VXB71_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452046.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            2352..3080
                     /locus_tag="VXB71_001999"
                     /pseudo
     CDS             2352..3080
                     /locus_tag="VXB71_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
BASE COUNT         1043 a          570 c          702 g         1033 t
ORIGIN      
        1 taaattcttt gagctttttt ctttttaaat attgattgtt tctaaaagtt ctagtaatat
       61 tgctatttct catttttcca aatatgttat tcaacttatt agctacgtct ctattcatat
      121 ttgggtataa aacaaaaaat caattctaac agttttatat cagaataata aataaaaaag
      181 cgatattcta gactgtatca atccttttcc attataggag caacagagtg ggagtagtca
      241 tctaaggact aatttatgta tttttacgag tcagtatctt gggatactgg tttttacttt
      301 tttagacttt ttgactactt gttaaaactg gggtaatttt cgactgttta acagttatta
      361 tgcaaagtct aaaagattag aattgtcaaa acaatccgtc taggcttgat tttatccttt
      421 atttactata aaatgagaag gaaaaatgtc aaacttttat attgcaaata ggagaaatca
      481 tgacaaaaac attaaaacgt cctgaggttt tatcacctgc agggacttta gagaagctaa
      541 aggtagctgt tcagtatgga gcagatgctg tctttatcgg tggtcaggcc tatggtcttc
      601 gtagccgtgc gggaaacttt actttcgaac agatggaaga aggcgtgcag tttgcggcca
      661 agtatggtgc caaggtctat gtagcggcta atatggttat gcacgaagga aatgaagctg
      721 gtgctggtga gtggttccgt aaactgcgtg atatcgggat tgcagcagtt atcgtatctg
      781 acccagcctt gattatgatt gcagcgactg aagcaccagg ccttgaaatc cacctttcta
      841 cccaagccag tgccactaac tatgaaaccc ttgagttctg gaaagagcta ggcttgactc
      901 gtgtcgtttt agcgcgtgag gtttcaatgg aagaattagc tgagatccgc aaacgtacag
      961 atgttgaaat tgaagccttt gtccatggag ctatgtgtat ttcatactct ggacgttgta
     1021 ctctttcaaa ccacatgagt atgcgtgatg ccaaccgtgg tggatgttct cagtcatgcc
     1081 gttggaaata cgacctttac gatatgccat ttgggaaaga acgtaagagt ttgcagggtg
     1141 agattccaga agaattttca atgtcagccg ttgacatgtc tatgattgac cacattccag
     1201 atatgattga aaatggtgtg gacagtctaa aaatcgaagg acgtatgaag tctattcact
     1261 acgtatcaac agtaaccaac tgctacaagg cggctgtgga tgcctatctt gaaagtcctg
     1321 aaaagtttga agctatcaaa caagacttgg tggacgagat gtggaaggtt gcccaacgtg
     1381 aattggcaac aggtttctac tacggtatac catctgaaaa tgagcagttg tttggtgctc
     1441 gccgtaaaat tcctgagtac aagtttgtcg ctgaagtggt ttcttatgat gatgcggtac
     1501 aaacagcaac cattcgtcaa cgaaacgtca ttaacgaagg ggaccaagtt gagttttatg
     1561 gtccaggttt ccgtcatttt gaaacctata ttgaagattt gcatgatgcc aaaggaaata
     1621 aaatcgaccg cgctccaaat ccaatggaac tattgactat taaagtccca caacccgttc
     1681 aatcaggaga catggttcgt gcattaaaag aaggactcat caatttttat aaggaagatg
     1741 gaaccagcgt cacagttcga gcttaagaaa ggaaaaggaa atgatagagg cacagggttt
     1801 cttagtggat aagcaaacaa gatgcattca ttaccatagc aagctggata ttattgcttt
     1861 acaatgctat gattgtaaaa agtattatgc ttgttatcgg tgtcatgatt cattagaaaa
     1921 tcaccctttt gagccttatc ccttatcttt gatacaggat aagcctattt tatgtggtgt
     1981 ttgtctaaaa ctattaacat ataagcaata taaagaaagc ttaagttgcc tcttttgttt
     2041 ttctcgcttt aatccaggtt gccaaaatca taaggaacgc tattttaaat agcaaatcat
     2101 ctagttttga agtaggagaa aactcaattc caagagaaaa tgaagtaaat cttcccacaa
     2161 taaaacgcat aatatcaaga ttgttcaata cctgatacta tgcgttttta agattttaaa
     2221 gacttttttc ctagcccctt tttactttat ctggtatttt gactacttgt taaaactggg
     2281 gtaattttcg actgtttaac agttattatg caaagtctaa aaggttagaa ttgtcaaaac
     2341 aatccgtcta gagtatgcgt gatgccaacc gtggtggatg ttctcagtca tgccgttgga
     2401 agtacgacct ttacgatatg ccatttggga aagaacgtaa gagtttgcag ggtgagattc
     2461 cagaagaatt ttcaatgtca gccgttgata tgtctatgat tgaccatatc tcagatatga
     2521 ttgaaaatgg tgtggacagt ctaaaaatcg aaggacgtat ggagtctatt cactatgtat
     2581 caacagtaac caactgctac aaggcggctg tggatgccta tcttgaaagt cctgaaaagt
     2641 ttgaagctat caaacaagac ttggtggacg agatgtggaa ggttgcccaa cgtgaactgg
     2701 ctacaggatt ttactatggt acaccatctg aaaatgagca gttgtttggt gctcgtcgta
     2761 aaatccctga gtacaagttt gtcgctgaag tggtttctta tgatgatgcg acacaaacag
     2821 caaccattcg tcaacggaac gtcattaacg aaggggacca agttgagttt tatggtccag
     2881 gtttccgtca ttttgaaacc tatattgaag atttgcatga tgccaaaggc aataaaatcg
     2941 accgcgctcc aaatccaatg gaactattga ctattaaagt cccacaactt gttcaagctg
     3001 gagacatggt tcgagctctt aaagaggggc ttatcaatct ttataaggaa gatggaacca
     3061 gcgtcacagt tcgtgcttaa tgtagttgtt tagttttaaa aaattatgca aagctccata
     3121 tacaacactt aaacgagatt aaagaatggc gaaatccctt gatgcgcaag agattagctg
     3181 tcctttttta ttttttaagt gataaagtcg gagcttaggt attaaagcct atcaaattaa
     3241 acaaagaagc gatgtcttag atattttgaa aaaaattaat aagcagaaaa ctctctatta
     3301 ttttgttgta gagagttttt tgttaataaa attttacaaa atgacatt
//
LOCUS       DAVLAQ010000106         3212 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000106 DAVLAQ010000000
VERSION     DAVLAQ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.106"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            32..226
                     /locus_tag="VXB71_002000"
     CDS             32..226
                     /locus_tag="VXB71_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0452047.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(592..1902)
                     /locus_tag="VXB71_002001"
     CDS             complement(592..1902)
                     /locus_tag="VXB71_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0452048.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2139..3011
                     /locus_tag="VXB71_002002"
     CDS             2139..3011
                     /locus_tag="VXB71_002002"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0452049.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3124..>3212
                     /locus_tag="VXB71_002003"
     CDS             3124..>3212
                     /locus_tag="VXB71_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0452050.1"
                     /translation="MWYNLLMAYSIDFRKKVLSYCERTGSITEA"
BASE COUNT          992 a          531 c          726 g          963 t
ORIGIN      
        1 atttttttat ttttcattac gaataatata gatgaagggg aaagagtatg aaaacagaac
       61 tgtttctttt gctattagtt caaaaggaga aaaaatgaaa gtagaaaata tttcgtatag
      121 ggtggatcat cgtatattgt ttgataatat ttcttttgat acttcgagtt caggcgtgac
      181 attaattact ggtaaaaatg gtacaggaaa gtcaacttta ctatagtaga ttgaaactag
      241 aatagtacac atctacttct aaaatattgt tagaaatcga tttgactatc ctgatctatt
      301 tgtcctgttc ttatttcatt tcactatatc tcaaattgag tatgacgaag tgcgctccca
      361 tgtcctggga acgcactttc ttcatatttt tcatattctt gaatccatcg ataaagacta
      421 ttgggatgaa tttttaaagt tgaactaatc atttttacag gatgagattt acagcagaga
      481 gtttgaaggc tttatcaaag gtttttcttg gcataatgac ttttcctcgt ttccacttaa
      541 ttttgtgtct actttattat accaagtcca cccttaagtt agataataaa tctaacttaa
      601 ggaagctaga aggatgagaa tccaggtggt caagagtccc aaacttaagc tgatggggac
      661 acccagaata atttgctttt tgaaggcaag gccacgttcc tctatattgg gaagtgagag
      721 ttgaatgaga gaaccagctg atgaaaaggg tgagatatta gtagatagag cgccaataac
      781 ggtggctgtt gtgagtaagt gaatatcaat ctgaggattt tgagcactga tgatagcaat
      841 gatgggaaag agggctggag ctacaacgga tagggtggaa ctaaagagtg acatcactcc
      901 ggctatcaca caaaagaaca gaggtaacca gaaatgagga atggttgttg tcatgaggtg
      961 ccctatcagt gtgactaaac ctgacttgac cgctagagac attagtaagc tcatgccgca
     1021 gagcatgata attgtagccc agggaacctt agctaaaatg gcttcttgct tccctaattt
     1081 gagccttaag gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa atgttttttg
     1141 ataagtagct atccaggcga tgtttgggaa aatgagatgc aacaagggaa aaagccaaac
     1201 caaaaccatg ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc tgaggagtgg
     1261 tggttggtca atagtcaagg atgagtttgt tcttccctta ctatagtgac tgtaacagga
     1321 taataaaagc aagacgatga gtgggtagat aatgctgacg ataaagatat gattgccaag
     1381 tgaaaaagct tgctcttccc atcccatttg cttaaacagg ccttgaaaga caatgcctga
     1441 gctactggtt atcaaattag cccctcctga agctccccaa ttgacggctt gagctccaat
     1501 caaagggtgt ttgtccgctt tttgacagag ggtaatcgct agaggacagc aaacggccat
     1561 agtagtgaaa aatccagcac ctaaagcaga caaaagggtt gccatcaggt ataaaatcat
     1621 gtagagggcg ttagggtggg tgcgtgtgcg gtagagaatg tgttgagcca aaacatcaag
     1681 agtaccgtta gttgttgcaa cgttataaaa gagagagacg ctaaaaatgg taaaaaagag
     1741 tgaggttggc caaaaatgaa gaagttcttt ggggcttaat cccatgagag tggttgcgat
     1801 gaggtaagaa aaagcaatag ccagcaggcc aatattgatt ttggtgcggt aaccaattcc
     1861 aatggctaga gcaatggcgc taatcattat taaatgaatc attgaattgt cctttcagtt
     1921 agaatatgga aataggttgg caattttggc gctcaaaaga ccacctgttt cctattggta
     1981 cttgactatt atacacaaaa aaaatacaat tgtcttgaca attgtattga cacttgttag
     2041 aattaaaaat gaggtattca ggcttgtgat ttcctatgga agttaatagt aattgcctct
     2101 agtgcttaca agtgatatta aaaatagagg acttagtgat gtcaatcatt tcaactgatt
     2161 taaccccttt tcaaatagat gatacattga aagcagcctt gcgagaagat gttcattccg
     2221 aagattacag taccaatgcc atttttgatc atcatggcca agccaaggtg tcgctttttg
     2281 ccaaggaagc tggtgtttta gcgggactaa ccgtttttca aagggttttt accctatttg
     2341 atgccgaggt gaccttccag aatcctcatc aatttaagga tggggatcgt ttgactagtg
     2401 gcgatttggt tttagaaatc ataggctcgg tgagaagtct cttaacatgt gaacgcgttg
     2461 ccttgaattt tttacaacat ttatcaggga ttgcttcgat gacagctgct tatgtagaag
     2521 ccttaggcga tgattgcatt aaggtatttg atactcgaaa aactactcct aatttacgtc
     2581 tttttgagaa atatgccgtg agagttggcg gtggctataa tcatcgcttt aatttatcag
     2641 atgctatcat gctaaaagac aatcacattg cggcagtagg tagtgttcag aaggcaattg
     2701 ctcaagcgcg tgcctatgcc ccttttgtga aaatggtcga ggtggaagtg gaaagccttg
     2761 ctgctgccga agaagctgcg gcggcgggtg ctgatattat catgttggat aatatgtcat
     2821 tggaacagat tgaacaggcc attaccctaa ttgcaggacg ttctcggatt gaatgttctg
     2881 gaaatattga tatgaccact attagccgtt ttcgtggttt agcgattgat tacgtctcca
     2941 gtggtagttt aacccatagt gctaagagtc ttgatttttc catgaagggt ttaacctacc
     3001 ttgatgtcta agttgtaaaa taaactaact ttttaaagga tgtctttcct ctagaacgag
     3061 ttttatgtca gatagtttaa acgcctcttc aaatatagta aaatgaacca aaaatagtac
     3121 acaatgtggt ataatcttct tatggcatat tcaatagatt ttcgtaaaaa agttctctct
     3181 tattgtgagc gaacaggtag tataacagaa gc
//
LOCUS       DAVLAQ010000107         3067 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000107 DAVLAQ010000000
VERSION     DAVLAQ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3067
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.107"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            129..1622
                     /locus_tag="VXB71_002004"
     CDS             129..1622
                     /locus_tag="VXB71_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0452051.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2177
                     /locus_tag="VXB71_002005"
     CDS             1635..2177
                     /locus_tag="VXB71_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452052.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLVKSRYSEEVVA"
     gene            2174..>3067
                     /locus_tag="VXB71_002006"
     CDS             2174..>3067
                     /locus_tag="VXB71_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452053.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIH"
BASE COUNT         1100 a          434 c          605 g          928 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaagggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc cgatattccg
     2161 aggaggtggt tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatggcta
     2221 tgcttttaaa cctcaagatt ggtcatctga agggaaagag attatcagaa tacagaatct
     2281 gactaaaact tcaaaaggga taaattatta ttcgggtacg attgataaaa aatacattgt
     2341 tgaagctggt gatattctta tttcgtggtc gggtacatta ggggtttttc agtggtgtgg
     2401 aagatccgca gtattaaatc agcacatttt taaagtggtt tttgataaga tagatataga
     2461 taaatcgtat tttaaatatg ttgttgaaaa aggtttacaa gatgctgtaa aacatactca
     2521 tggttccaca atgaaacatt taactaaaaa atattttgat aatattatag ttccatatac
     2581 aaatttggga gagcaacaaa gaattgcaag tgagctggat ttgttaagca agctgatttt
     2641 aaggagacaa gaacaacttg aagagcttaa tctacttgta aaatcccgat ttaacgagat
     2701 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
     2761 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
     2821 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
     2881 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
     2941 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
     3001 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
     3061 tatccat
//
LOCUS       DAVLAQ010000108         2950 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000108 DAVLAQ010000000
VERSION     DAVLAQ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.108"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..159
                     /locus_tag="VXB71_002007"
     CDS             <1..159
                     /locus_tag="VXB71_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452054.1"
                     /translation="NNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFDM
                     AKTQIETD"
     gene            251..1099
                     /locus_tag="VXB71_002008"
     CDS             251..1099
                     /locus_tag="VXB71_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0452055.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVW"
     gene            1145..1930
                     /locus_tag="VXB71_002009"
     CDS             1145..1930
                     /locus_tag="VXB71_002009"
                     /inference="COORDINATES: protein motif:HMM:NF024800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="HEV0452056.1"
                     /translation="MNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFY
                     YYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTS
                     EIEREIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKLDEL
                     ESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALISEIQVYE
                     EKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            2198..2764
                     /locus_tag="VXB71_002010"
     CDS             2198..2764
                     /locus_tag="VXB71_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452057.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         1111 a          371 c          639 g          829 t
ORIGIN      
        1 aacaatgact ggaatggatt ggctgattta atagcaaatc tgattgcaaa atatgctggt
       61 gctttagatt tagataatct acccgatcca acgccagcaa aaaatcaaga gatgaaaaat
      121 agttttgaca tggcaaaaac acaaattgag acggactaat aaaagtgtta taatatactt
      181 gaaatgatag tccaaactta aattaaaaaa attatatatg atatagaaaa attatattga
      241 ggttaatact atgtcaaaag aaaaaataaa agtatacctc tatacacgag tatctacgtc
      301 aatacagata gaggggtatt cgttaggggc acaaaaatca cgaatgaaag cttttgctat
      361 ttacaacgat tatgaaattg ttggagagta tgaagatgcc gggaagtctg gcaagtctat
      421 tgaaggtaga atacagttca atcgaatgat ggaagatata aaatctggaa aagatggagt
      481 atcttttgtt cttgtgttta agttatcaag atttgcaaga aatgccgctg atgttctttc
      541 tacacttcag ataatgcagg attatggagt taatcttatc tgcgttgaag atggcattga
      601 ttcatctaaa gatgctggga aactaatgat ttctgtttta tcagctgtgg ctgaaataga
      661 aagagaaaac atccgtattc aaacaatgga aggttgcatt caaaaagcaa gggaaggaaa
      721 atggaatggt ggctttgctc cgtatggata taaacttgaa gacggcaagc tgtttataaa
      781 tgaggaagag gcagttgcaa taagaacgat tttcgaccag tatgtaaata ctacgatagg
      841 agccaatggg atatctaaat acttagagaa tcatggaatt agaaaaatcc caagacagaa
      901 tggtaagaat cctttgtttg atgcaggtct tataagaaag atattaaaga atcctgtata
      961 taatgggaaa atagcatttg gaagaagaac tttagaaaaa gttcatggta caagaaatga
     1021 atataagcag gttgaacaag atgaatatct aatatctgaa gggatacatg aagctatagt
     1081 ttccgatgaa gtttggtaag ctgctcaggt taagctaaaa tctcaagcaa agaaatatga
     1141 gcatgtgaat aaaggaaaag atacacgcac acacttgctt tctggaattg taaaatgccc
     1201 gatatgtgga gtgggaatgt ttgggaacaa gtgtatcaag aaaaagaaag atggcacaaa
     1261 gtataaagat ttttattact atggttgtaa acataggcag atgataagag gtcataagtg
     1321 tacattcagt aagcaaatta gagaagaatt gttagatgat gctgttgcag aggtgattgt
     1381 caagatagta agtaatccga aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt
     1441 ggatacctct gaaatagaaa gagaaataga taattaccaa aaggaattga gaaagagtca
     1501 ttctacaaag tttaagctaa ttgaggaaat agataattta gatgttgaag ataagcatta
     1561 taagagaagg aaacaggatt tagatgatag actatatcgt atgtatgaca aactagatga
     1621 attagaatca tcactaattg atgcgaaagc aaagaaacag actattgaag ctgaaaagct
     1681 tacaggagat aacatatata aggttctgat ctattttgat aagctctata aagtcatgaa
     1741 tgatgtagag cgtaggcagt taatttcagc tttgatttct gaaattcaag tttatgaaga
     1801 aaaacaatct aacggacaat ggctaaaatc cattactttt aagctaccaa ttatagaaga
     1861 aaatctcaac ataggtttgg acaatgatga acaagttgaa tgtgtaagtt tattagagaa
     1921 acgtagttaa tcctcaaaag gttccccgaa ccttttgagt cccactgacg catcacgctg
     1981 aggcggtatc actgcttgta cgagttgaag catcagcaaa gtaaaagtag atgttcagcc
     2041 aatgcgacga ggtgagaccg aaggtcgata aggtgtgttc tgggtataag actcgtaaag
     2101 taagtaggaa atatgatgag atgatacaga gagcctgaat tggtcaggtg acgtgcttat
     2161 ttacattagc ctgataatga aaatggagag attatcgatg gttatattgg aattgtacca
     2221 aaatgattat tctaaagatt tagtagcatt tgattccata gaagatggga aagcctttgt
     2281 agctcaaatc ccgggataca ctctggaaac agaagatggt tttgaagtgg agtattttaa
     2341 tcctaaaaac ataccggatt atatggaaat tatttttaac ggaaatattg ttcctttatc
     2401 taaatttatg ttcgatcctg aggaaaatgt aaacattatt tggaaagaga tttcaaattt
     2461 atccctcaaa aatgatagag tgatcgaagg atattcaaaa attgatgcat atgtcgttaa
     2521 caaccatgaa gttaaagcct atgtcgaaac aagagaaacg aactatcgta aagcaaaaga
     2581 cttcttagaa agccgcggat atgaaatcga cagaagcttt ttcggaagtg aagacggtga
     2641 agcgattctt tacagaaaaa aagggatcga agtttggcat ttcttgtgtc acttagaccc
     2701 aatgtttgta gagattgaag atgtagaagg atatgttaaa gaagaagttg gagagattca
     2761 atagtcaacc aaagttcctt gtgagtatat acctttgcta gtaaaagagt caaaacgtta
     2821 taacgaaggg ggggaagaaa acccttgagt gtaagtcttt ttcttgttta gagggaaagt
     2881 attagagtag ccgctcataa tttatactag atttgataac tgatttgaga cagattttat
     2941 ttctataaat
//
LOCUS       DAVLAQ010000109         2927 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000109 DAVLAQ010000000
VERSION     DAVLAQ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.109"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(138..671)
                     /locus_tag="VXB71_002011"
     CDS             complement(138..671)
                     /locus_tag="VXB71_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0452058.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(760..1536)
                     /gene="recX"
                     /locus_tag="VXB71_002012"
     CDS             complement(760..1536)
                     /gene="recX"
                     /locus_tag="VXB71_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0452059.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1574..>2927
                     /gene="rlmD"
                     /locus_tag="VXB71_002013"
     CDS             1574..>2927
                     /gene="rlmD"
                     /locus_tag="VXB71_002013"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0452060.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          920 a          530 c          536 g          941 t
ORIGIN      
        1 cgaattctgc ataaatctct ttctagtaat gtgttgtaac tctgctataa tggatttatt
       61 cctttttgta tttacacaat ttattttata ctaccaaaaa aacaaggtca ggattttgtt
      121 cctgaccttt gacaacttta ccgattcttt agttctacat agcgcttgta ccaaatgttt
      181 acataggctt ctgagaaagg accacgtcca ttgttaatcc aatcaacaag aattttgaca
      241 tgttctttta aaatatagtc caagtcatca gaataattca ttttgcgttt gtgacgctcg
      301 tattcttcaa cgtccaagag acgtttttcc ccatctgtaa aaattttaac atccaaatcg
      361 taatcaatat acttcagtgc ttcttcatcc agatagtagg ggctagccat attgcaatag
      421 taagaagttc cattatcacg aatcatggca atgatattaa accaatattt cttgtgaaag
      481 taaacaatag ccggttctcg agtgacccaa cgacgaccat cactttcggt aacaagtgta
      541 tgatcgttga caccaataat ggcgttttct gttgttttta gtaccatggt gtcccgccaa
      601 gttcggtgga gactcccatc atgcttataa ctttgaattg taataaagtc gccttctttt
      661 ggaagcttca taactaacca actttctaca atttataagt ttatcattta ctattgtacc
      721 ataaaattac ctaaaatctg tgaatttcac ttggaaatat taaagatatt ctctaagagc
      781 gcttgctata tccgaaaaat cgtagccctt tcgtgctaaa acttgagtta aacgctgctt
      841 cagttcgtat ccttcatact ttcgagcata cttagtatat tgcttatcaa gttccttgaa
      901 gatgagttct tgagtcgttt cttggtcaac ttggctatct aagtcgtcaa aggcaatttt
      961 agcatcagaa taagagaagc ccttgttagt caagttctgg ataatcttat cttgcagggc
     1021 acgagctgga agttttccct catatttttt caatagttta ttggctacac gttgagcaac
     1081 ttcagaaaaa tcaaattctt tcaagttctc ttctatagta gattttgaaa tccctttttg
     1141 agatagtttc tgagtcagca cataaggacc cttgtctcct gaaagttgat tggtattgat
     1201 gatagcataa gcgtactgac catcattaat ccacttatct tctttaagat tagcaataac
     1261 ttgagaaacg atgtttttat caatatcgta ttttttcaga tattctctga cttctttttc
     1321 agtgcgtgct ttaaaggata agtggtagag agcgagattc ttaccataag aaaattgagc
     1381 aaagtcttga atctctttca attcctcttc gcttatcacc ttatctctcg ataacataaa
     1441 acgaacaatt gtatcttcgg tgatatagca tttgtcgcca ttatcaagct ccatcaggta
     1501 gagtcttttt ttcttttcaa gttttgtgat tttcatagct ctattataac tcaaaatgtg
     1561 ataagatagg ggtatgaatc tgaaagtgaa acaaaaaata ccattaaaaa tcaagcgcat
     1621 gggaattaac ggtgagggaa tcggctttta ccaaaaaaca ttagtctttg taccaggagc
     1681 tctcaaaggc gaagatatct attgtcagat tacttctatt agacgcaact ttgttgaagc
     1741 aaaattactg aaggtcaaca agaagtctaa atttcgaatt gtgccatctt gtactattta
     1801 taatgaatgc ggaggctgcc aaatcatgca cctgcattat gataagcagc tggagttcaa
     1861 gacggactta cttcatcaag cgctgaaaaa atttgctcct gcaggatatg aaaattatga
     1921 aattcgtcca actattggaa tgcaggaacc aaaatattac agagctaagt tacaatttca
     1981 gactcgaaaa tttaaaaatc aggtcaaggc gggcttatat gcacaaaact ctcactattt
     2041 agtagagttg aaagactgcc tggtacaaga taaggaaacc caagtgattg ctaatcgctt
     2101 agcagaatta cttacttatc accagattcc aatcacggat gagagaaaag ttctaggtgt
     2161 ccgtactatt atggtccgac gcgcgagaaa gaccggacag gttcagatta ttattgttac
     2221 aaaccgccag cttaatttaa ctcaattggt aaaagagttg gttaaagatt tcccagaagt
     2281 tgtgacagta gctgttaata caaatacagc taaaaccagt gagatatatg gtgaaaagac
     2341 agagattatc tgggggcaag agagtattca agaaggtgta ctcaattatg aattttcact
     2401 atcccctcga gctttttatc aactaaatcc tgagcaaaca gaagtcctct atagcgaagc
     2461 agtaaaagcg ctggatgttg ataaagaaga ccatttgatt gacgcttatt gtggagttgg
     2521 aacgattgga tttgcctttg caaagaaagt taaaacactc agaggtatgg atattattcc
     2581 agaagctatt gaagatgcca agcgaaatgc taaaagaatg ggatttgaca atactcatta
     2641 tgaagctgga acggcagaag agattattcc tcgttggtac aaggaaggct accgagcaga
     2701 tgctttgatt gttgacccac cacgtacagg tctggatgat aagttattag atactattct
     2761 tacttatgta ccagaaaaaa tggtttatat ttcttgtaat gtttcgacct tggctcgtga
     2821 tttggtacgc ttagtagaag tctatgatct tcattatatc cagtcggtcg atatgttccc
     2881 acatacagct cgaactgaag ctgttgtaaa attaataaaa aaagttt
//
LOCUS       DAVLAQ010000110         2713 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000110 DAVLAQ010000000
VERSION     DAVLAQ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.110"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..2680)
                     /locus_tag="VXB71_002014"
     CDS             complement(<1..2680)
                     /locus_tag="VXB71_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0452061.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEAPKEYTGVQAGAIVEPEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAI
                     VEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKV
                     TGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANN
                     IHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPARKYTH
                     LKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILS
                     PTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKD
                     GNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVT"
BASE COUNT          689 a          558 c          430 g         1036 t
ORIGIN      
        1 ttgtaactgg tagcatcaca tctttaaagt tctctgattt aactttcata aagtaatttt
       61 ctgcattact tggtaaagaa gcaagtgaag ttacatgtcg atacttatta ccatcttttg
      121 aatatagttc tacagaagat atatttctaa gttctaattt cttaataact tctttttcat
      181 ctttagcgtc atcttttttc tcatctttat gacgataaag ttcatcgtat actggtggaa
      241 tttcattacc tgctataata ctcttaatcc aagctaattg tgtaggagat aaaatcaatc
      301 cgcctgagcg attttgtgct ccattttgat gcacaccaat aacttcacca ttagcattaa
      361 atattcctcc accactcata ccaggatttc caccttgata ttgaacaccg taggtgttat
      421 tcgcatattc ttgttccatt tctaccgtag catcttttaa gtgcgtatat ttcctagctg
      481 gatatccatg aacatttagt ttgtcattaa gatttacttt cgaataattt ttaactaatt
      541 ctacatgttc tctgccagtt gtttcaggta gcttaatcac tgctaaatca tagataaatc
      601 cttttggata atctttttta ttataaaaat gaatattgtt agcagtaaat gttccttttt
      661 gtccatcagg agtcacccac tcatatacgt ttttagattt atcacctcta aattcgccag
      721 tagtattatc agtagaatta ttaatgaaat tatgtgctac tgttaaaagt acatttggtg
      781 caataaaagt agctgatcct actccagtaa ccttcgacga atctgtaata aagttcatat
      841 taattaatgc actagatttt ttctgaatac tcatttcttc tggtgtatta gtattttcat
      901 tatttggttt agtatcttct gcactaggtt gttcgatttt accagtatat tctttcagtg
      961 cttctacttt ctctggctcg actatcgctc cggcttgcac ccctgtgtat tctggtagtg
     1021 gtgctatctg ctctggttca acaatagcgc cagcctgcac ccctgtgtat tcttttgatg
     1081 gttctacttt ttctggttct actattgctc cggcttgcac tcctgtgtat tccttcggtg
     1141 cttctacctt ctctggttcg actatcgctc cagcctgcac tcctgtgtat tccttcggtg
     1201 cttctacttt ctctggctcg actatcgctc cggcttgcac ccctgtgtat tctggtagtg
     1261 gtgctacctg ctctggatca cccttgtcag tcatgactgc ctctggtaac gctggttgaa
     1321 cttctggtac gcctttatca cttactacag cttctggcaa ctctggttgg actgctgact
     1381 cacctttgtc ggttaataca gctgctggta gttcaggctg aattgcgggt tcaacaatag
     1441 ctccagactg tacttcctta tgttctgcac cagtctcagc ttgttccttt ataacttgag
     1501 cttttttagt acctttttcg actattcttg aaacaggcgc agtcgttgaa gttgaaataa
     1561 tttctcgtga aacttcttca ttgtttacag aaaatattct gacgatttca actttcttac
     1621 ctaatgcacc ttcttgtttt actcttacag ttccttctgc taaatcagga ttttcttgaa
     1681 tttcttcttg aaaatctatt tttgtttcta tagtttcgtc acgatataag agttccggtt
     1741 tgttcaactg acctgatagc acttcatcct gtggatttaa tgtatttacc ccagtctttt
     1801 cctttggaga aatcttctcc tctttcttcg tttctagatt cttatgttcg gctaattgtt
     1861 cttgagaatc tgaagattgt ttctcttctt ttcttggatt gattaattca gtagagaaag
     1921 gtttttcaac tacttgaact tctgtcggct tagttgaaga aacaggtgtt tgttcctgaa
     1981 tagcttgtac tgttgatgga tggtctacaa aatttggtgt aacattataa tccacctttt
     2041 gttgttttgt aggagtggct gctgattttt cttgattact tacttcaaaa tcagaagtcg
     2101 tttttccctc tttgatatat ccaatataag tgtaacctga aatctcttta ggaagaggta
     2161 atttttctcc agaggtcaat tcatagtccg tattgtaatt tagcaaaaga tgattttcta
     2221 aagcatggac tgaaactaag acaccatttc ccattcccgc aaccaatact aaatgtaata
     2281 ccgttttatt cttaaccttt ttcttggaaa cagcaaaaat taaaattccc agagcagcta
     2341 agctagcacc agcaactagg gcttgcctct cattcttgct tccagtattt ggtaattccg
     2401 ccagttgatt ttgagaattt aacttataaa caagataata agtttcatca tcattctcca
     2461 cgtatgtcgg aatatcatag acaagctgct tcttttcttc tgatgatagc tctgaatctg
     2521 ccacatattt atagtgaact cccgcagttt cttgagcatc cacagatgaa ctagctaata
     2581 cagacataaa aaataaactt gaaatcgttg cagatacaag tcctactgat aattttctaa
     2641 atgaaaaacg ctcttgtttt tcaccaaaat acttttccat tattcctcct tgaaataaaa
     2701 tttatatatg tta
//
LOCUS       DAVLAQ010000111         2660 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000111 DAVLAQ010000000
VERSION     DAVLAQ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.111"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..187)
                     /locus_tag="VXB71_002015"
     CDS             complement(<1..187)
                     /locus_tag="VXB71_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452062.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRD"
     gene            complement(245..958)
                     /locus_tag="VXB71_002016"
     CDS             complement(245..958)
                     /locus_tag="VXB71_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0452063.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1416..1796)
                     /locus_tag="VXB71_002017"
                     /pseudo
     CDS             complement(1416..1796)
                     /locus_tag="VXB71_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(2213..>2660)
                     /locus_tag="VXB71_002018"
     CDS             complement(2213..>2660)
                     /locus_tag="VXB71_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0452064.1"
                     /translation="RNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDE
                     KENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEK
                     VTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESK"
BASE COUNT          823 a          532 c          414 g          891 t
ORIGIN      
        1 aatcccttct cccaatataa tccccttctt tgactaatga tggagatttc caagtaaaaa
       61 ttaaatcgcc agagaaattt ttcttatcaa aaaacttaaa aagagattga taaatactat
      121 ttgctaattg acaagtgtca gatgtaaatt cataattaac agcttcatta aaatcaactt
      181 cagacatttc aatgtactct tcaatagtaa tattagcttt tttgtagtca ttagctcgtc
      241 tcctttaaaa tgtgatcttt tcaagaatat ttttatctaa acaatccagc aagtcttggt
      301 aagaatagac ttcgtaagtc ggctgggctt gtgtgtgatt ttcgaggtga tgaggattat
      361 accagatagt gtcaatcccc gcattattgc caccttgaat gtcggcggtt agagaatctc
      421 caatcatcag cgtcttttct ttactaaatc cagcaatttg ctggccaatc ttttcataaa
      481 aaagagcatc cggcttttga gtttgcaact gttctgagat aaagacttga ttgaaataag
      541 gtgctagacc agattgagcc aaacgtcctg tctgaatggc agtaatgcca tttgtcgcag
      601 catacaagtc ataatcacgc tcaatgaggc tgtccaagag atcatgagcg cccgatagtg
      661 tttgtccctg ctgagcgaga taaaattggt aacgctgggc aagaaaacta ccgtcttttt
      721 cctgtccaaa atgagaaaat aaacgagaaa agcgcgtgtt aaccagctct tgtttactga
      781 ttttcttcag ctccaagtct ttccagagag ccttgttcat aggaacgtaa taatctttat
      841 aagcctgaat atccgcaact ccttcttctt ttagaagttg ggtcaaagcc acatcctcag
      901 cagcatcaaa atcaagaaga gtgtggtcga ggtcgaagag tagaaatttg tagaacaatt
      961 tgaggttttc ctttctgaaa attcattaag aacattatat cataaagcac ctcatacaat
     1021 taactaattt aatcacttaa aaaaattcga acactttcta tacaactgac agctcaaatc
     1081 tttcagaata gaacaatact aactatcgag caccccgtat tcataaatat atgtgtaatt
     1141 ctagacctag aattcctata aactaaatgc tttcatactc ttccaagtaa ttgattgcct
     1201 taaattttaa tttttgaagg tttctaaagc tagaatagcc ccatcacaat cagttttgat
     1261 tgattcacaa tttagaaaca ctatagtttc actcctgtta aaataaaaag gaactgcata
     1321 aagcaatccc tttctgattt tgaaatcatt tacttaacat tttatagttg agataatcaa
     1381 tagcttacct ataaaaagag ttatagtaaa attccttatt tattgatttc aagctccgct
     1441 aactgtgttt gaataactga cagttctgca ccagcctgaa gaagagcagc tgcattatag
     1501 gcaccttcta caattggaac cctgttgatg atgatacttt tatcactgaa atcagtcacc
     1561 atttttaagt tcattttagc agaacctagg tcaaaaaagg caagtaaagt atctgctgta
     1621 ttttcggaaa caaccctatc tacttaatca aaactcgttc caattcctcc gccctcggtt
     1681 cctcctacat aagtaatcgg aacatcttta gctactttac taatcagttc aacaacacct
     1741 tctgcaatgt gtttggaatg tgaaacgata acaagaccaa taccaatact ttccatcaaa
     1801 ccaccccagt ttctaaaata gcagtaaaga gtaatcctga tgagaatgat ccaggatcaa
     1861 tatgtccaag aaaccatatg ctcctaagac aagagccaac agactggtca tcaataatag
     1921 tattgttctt tttttcatca ttactcctta actagtgttt aactgattaa ttagccagta
     1981 aatagtttat ctttatttac actatctgtt aagatatagt aaaataagaa caggacagtc
     2041 aaatcgattt ctaacaatgt tttagaagta gaggtatact attctagttt caatctacta
     2101 tattttgcac attttcatga aaaaaatgag aactagaact cacattctgc tctcattttt
     2161 cgttttcccg ttctcctatc ctgtttttag gagttagaaa atgctgctac ctttacttac
     2221 tctcctttaa taaagccaag agactatcta cttctgctga aatagtgtta ttatctttcg
     2281 ttccgagaag aagactactt tttagaccag tcaatgtctc cacagcattt tgtctaatac
     2341 tagaatctgt tactttttct agcaaggcct ccgcatctgc tatcttagcg ttaataacag
     2401 aatgctctac ttgaggaatt tcagcctcat ctgtagtatc ttcagcttct tcctctgtct
     2461 cttccgtatc agtgcttggt ttataaagat tatctgctga aggatttaaa ccagcgtgat
     2521 tctctttttc atcagattca gggtgagttg gctcacttac ttcatcatgt tccttatctt
     2581 cctcaggttt ttctgtctga ggtttctcct cgtttggttt ttccgtttga ttggtatcag
     2641 cttgaccatt tttgtttctt
//
LOCUS       DAVLAQ010000112         2603 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000112 DAVLAQ010000000
VERSION     DAVLAQ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.112"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            144..1340
                     /gene="tuf"
                     /locus_tag="VXB71_002019"
     CDS             144..1340
                     /gene="tuf"
                     /locus_tag="VXB71_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0452065.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(1449..2603)
                     /locus_tag="VXB71_002020"
                     /pseudo
     CDS             complement(1449..2603)
                     /locus_tag="VXB71_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          797 a          507 c          555 g          744 t
ORIGIN      
        1 ttaaattttt accaagaata attcacaaaa acgttgtaaa acacttgcaa tttagctgaa
       61 atttgataaa atagtaagga aagttagact gtattgccta ctgtctatct ataaaatata
      121 ttttattgga ggcttttact caaatggcaa aagaaaaata cgatcgtagt aaaccacatg
      181 ttaacattgg tactatcgga cacgttgacc acggtaaaac taccctaact gcagctatca
      241 caactgtttt ggcacgtcgc ttgccttcat cagttaacca acctaaagac tatgcgtcta
      301 tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat caacactgcg cacgttgagt
      361 acgaaactga aaaacgtcac tacgctcaca tcgacgctcc aggacacgcg gactacgtta
      421 aaaacatgat cactggtgct gctcaaatgg acggagctat ccttgtagta gcttcaactg
      481 acggaccaat gccacaaact cgtgagcaca tccttctttc acgtcaggtt ggtgttaaac
      541 accttatcgt cttcatgaac aaagttgact tggttgacga cgaagaattg cttgaattgg
      601 ttgaaatgga aatccgtgac ctattgtcag aatacgactt cccaggtgac gatcttccag
      661 ttatccaagg ttcagcactt aaagctcttg aaggtgactc taaatacgaa gacatcgtta
      721 tggaattgat gaacacagtt gatgagtata tcccagaacc agaacgtgac actgacaaac
      781 cattgcttct tccagtcgag gacgtattct caatcactgg acgtggtaca gttgcttcag
      841 gacgtatcga ccgtggtatc gttaaagtca acgacgaaat cgaaatcgtt ggtatcaaag
      901 aagaaactca aaaagcagtt gttactggtg ttgaaatgtt ccgtaaacaa cttgacgaag
      961 gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt tcaacgtgat gaaatcgaac
     1021 gtggacaagt tatcgctaaa ccaggttcaa tcaacccaca cactaaattc aaaggtgaag
     1081 tctacatcct tactaaagaa gaaggtggac gtcacactcc attcttcaac aactaccgtc
     1141 cacaattcta cttccgtact actgacgtta caggttcaat cgaacttcca gcaggtactg
     1201 aaatggtaat gcctggtgat aacgtgacaa tcgacgttga gttgattcat ccaatcgccg
     1261 tagaacaagg tactacattc tctatccgtg agggtggacg tactgttggt tcaggtatgg
     1321 ttacagaaat cgaagcttaa ttcgatttag ttcccagaag aacaattatt taagtcagac
     1381 actaaaagaa tcttgcttgg caaggttctt ttttggttct ttgtcaactg tagtgggttg
     1441 aaaaaaaact aagctcgaga aaggacaaat ttcgtccttt ctttttgatg ttcagggcga
     1501 tgaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg cgcttgataa
     1561 gtttgatgag attattggtc gcttccaatt tggcgtttga atagggtagt tgaagggcgt
     1621 tgacgatttt ctctttgtcc tttagaaagg ttttaaagac agtctgaaaa agaggatgaa
     1681 cctgcttaag attgtcctca atgagtccga aaaatttctc cggttcctta ttctgaaagt
     1741 gaaacagcaa gagttgatag agctgatagt ggtgtttcaa gtcttccgaa taactcaaaa
     1801 gcttgtttaa aatctcttta ttggttaagt gcatacgaaa agtaggacga taaaatcgct
     1861 tatcactcag tttacgacta tcctgttgta tgagcttcca gtagcgcttg atagccttgt
     1921 attcatgaga ctttcgatga aactgattca tgatttggac acgcacacga ctcatagtac
     1981 ggctaagatg ttgtacaatg tgaaagcgat caagaacgat tttagcattc gggagtgaaa
     2041 cagtctggga gactgtttca gcctgagcct agaaatttga aagcgaagct gtttagctaa
     2101 gtcatagtaa ggactaaaca tatccatagt aataattttg acgcgacatc ggacggctct
     2161 atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccctcaa gaacagtgat
     2221 gatattgaga ttgttaaaat cttgcgcaat gaagctcatc tccatctccc gattgaaaca
     2281 gtcactcccc ggactgtttc aacgtcccag gacataatct caggaagacg cgaaaaatca
     2341 tgctcaaagt gagaatcatt gagcttgcga atgacagttg aagttgagat ggaaagctga
     2401 tgggcaatat cagtcataga aatcttttca attaactttt gagcaatctt ttggttgatg
     2461 atacgaggga tttggtgatt cttcttgacg atagaagttt cagcgaccat catttttgaa
     2521 cagtgatagc acttgaatcg acgctttcta aggagaattc tagtaggcat accagttgtt
     2581 tcgaggtaag ggatcttaga cgg
//
LOCUS       DAVLAQ010000113         2589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000113 DAVLAQ010000000
VERSION     DAVLAQ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.113"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..368)
                     /locus_tag="VXB71_002021"
     CDS             complement(<1..368)
                     /locus_tag="VXB71_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEV0452066.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRP"
     gene            complement(461..619)
                     /locus_tag="VXB71_002022"
     CDS             complement(461..619)
                     /locus_tag="VXB71_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0452067.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(690..1119)
                     /locus_tag="VXB71_002023"
                     /pseudo
     CDS             complement(690..1119)
                     /locus_tag="VXB71_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1214..1654)
                     /locus_tag="VXB71_002024"
     CDS             complement(1214..1654)
                     /locus_tag="VXB71_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0452068.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            1645..1953
                     /locus_tag="VXB71_002025"
                     /pseudo
     CDS             1645..1953
                     /locus_tag="VXB71_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2108..2431)
                     /gene="tnpB"
                     /locus_tag="VXB71_002026"
     CDS             complement(2108..2431)
                     /gene="tnpB"
                     /locus_tag="VXB71_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0452069.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
BASE COUNT          786 a          537 c          491 g          775 t
ORIGIN      
        1 gggcgattga tttttacttc cgtcgcatca atcattaccg tgtcctcaga actgagagga
       61 gttcttgaaa tcgtaacacc actttgaaca agagttactt caacccattg gctccgacgg
      121 attaagttgc tttcgtgaat accaaaaaca gccgcaattt gttcataagt tcgatattct
      181 cgcacatatt gaagagtggc cataagaagg tcttctagac ttaatttagg ttttcgtcca
      241 ccttttgcgt gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtc
      301 gtgcgttgaa caccaacaag acgcttaaat cgtgcatcgg ttagttgttt acttgcttca
      361 tcattcatag aactactata ccatattttg tttcgcagga agtctattga aaaatctcca
      421 gactggagaa ctcacggata gttcctaatc tggagatttc ttatttgcac ttttcttgta
      481 caactttagt ccatggtaaa taagcctcta aaacctcttt gtttacgaga gtttcctcgt
      541 ttggaagaca ttctagaaga taggatagat atttctcgct atttaattga tgacgtttag
      601 ctgtttccaa caaactcata ataatagctc ttgctttagc tccttcaaaa ctttgagaaa
      661 ataaccaccc tcgctttttt aaactgagct taggctaaaa gagtccactg gactctttta
      721 ctccgtccca taaccaatga tttaatggcg cgttcagcta gattattgga aaggaccaga
      781 tgtccgtctt tcaaaatggt cttaaaggtt tcttcatact tgaggctgta ttcaattgcc
      841 cttcctagtt ttgaacctgc taaaactgac tgacgccggc actaagcaaa gaagtcttcc
      901 attaagggct ggagatgttc ttgacgtttc tgtagtcgtt catcagctgg caaagcctcc
      961 cagtctcttt ccaaggaaaa taactgatca caataagcta aacctttagc tcctaaggat
     1021 gatttatccg cttgcttggg ggggcgcttc aaaaaacttc cttctcacat gcgcccaaca
     1081 tccaacaagt tcagcttctt ccagttgacg ataagcagac gagcggttcg aagtttacca
     1141 agcttagcgt cgccttgctc ctaaaccttg gactgctatc gcataggcag aactagagga
     1201 ctaaagtcct aagttactgc cgcaaaatat cacaatgcac atagccagaa taatctccta
     1261 ggaattcttg tactactgaa ccacttcgac actgatcatg gtggtaaagc gtaatccctt
     1321 gtttctctgc tttacctgac aaaaaagtcc aatagtaagt cagctgacta tcactctcta
     1381 gcaccctata agaagtttca tccgcatgaa gtaagggctg agtcaatagt ctctctcgca
     1441 agaggttata aaggggctcc aaatagtatt gactcgcctt gatatgccaa ttagagattt
     1501 ccttacgtgt gattggtaaa cccatcctag cccaatcttc ttcttggcga taattgggta
     1561 ccttcagatt aaacttctga tggatggtgt gagcgataat agaagctgag ccaaagttat
     1621 gcgctaaagg ggctttagga ataggagatt tcacaagctt atccagatga ttatctttta
     1681 ctcgttatgg acaatgctat atggcataaa tcaagtacct taaagattcc gactaatatt
     1741 ggctttgcat ttattcctcc atacacacca gagatgaacc ccattgaaca agtgtggaaa
     1801 gagattcgta aacgtggatt taagaataaa gccttttaaa ctttggaaga tgtcatgaat
     1861 caactccaag atgttataca aggactggag aaggaggtga taaagtccat cgttaatcgg
     1921 agatggacta gaatgctttt tgaaagcaga tgagtataaa aagaaagtcc tcatttcaat
     1981 agaaatcacg actttctgat ggatttatag taaaatgaaa taagaacagg acaaatcgat
     2041 caggacagta aaatcgattt ctaacaatgt tttagaagca gaggtgtact attctagttt
     2101 caatctacta tatttttgga gtgatagaaa agcccttcat aagccagtct acttgttctg
     2161 gtgtgagagc tttgacatcc ttttctgtac ttagccaaat caatctgccg ttctcaaagc
     2221 gtttatatag tagccaaaat ccttgaccat cccagtaaag gactttaaag cggtctttac
     2281 gtccaccaca aaagagaaag acttgaccgg agaaaggatc caattcaaag tgggttttaa
     2341 ccagataagc cagtgaatcg attccttgtc tcatatcagt tttcccacac acgagataga
     2401 cctcccctag gctagataga tgaattgtca tagagcaaca ccttatccaa aagctgttct
     2461 accatttcga gattgagaga ttgaaaaaaa cttacttcaa gcttgccaat acgaatttta
     2521 agcagaatat catttctctt tttagaatca aaacgacgag attgtggaat ctctacagga
     2581 acaataggt
//
LOCUS       DAVLAQ010000114         2535 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000114 DAVLAQ010000000
VERSION     DAVLAQ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.114"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..559
                     /locus_tag="VXB71_002027"
     CDS             <1..559
                     /locus_tag="VXB71_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452070.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VXB71_002028"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VXB71_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0452071.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VXB71_002029"
     CDS             1424..2029
                     /locus_tag="VXB71_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452072.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VXB71_002030"
     CDS             complement(1977..>2535)
                     /locus_tag="VXB71_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452073.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          868 a          364 c          435 g          868 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaacca tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgaac aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtcct ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacacta agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 ccttttatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DAVLAQ010000115         2499 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000115 DAVLAQ010000000
VERSION     DAVLAQ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.115"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..775
                     /locus_tag="VXB71_002031"
     CDS             <1..775
                     /locus_tag="VXB71_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0452074.1"
                     /translation="GYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDEYM
                     SDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGT
                     SFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGIT
                     GVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIK
                     KAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            785..2401
                     /locus_tag="VXB71_002032"
     CDS             785..2401
                     /locus_tag="VXB71_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452075.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          904 a          275 c          466 g          854 t
ORIGIN      
        1 tggctatacc aatcatagaa ttaagttaat tttaagtaat gaagatttag gtgcaactaa
       61 tgccagaaac ataggtatca aaaattctag aggtaagtat atatcatttt tagacgatga
      121 tgatgaatat atgtcagatc gaattttaaa gttgatggct tgttttaaaa agagtagaat
      181 gaagaattta gctttagttt atagttatgg aataataatt tatccaaatg gtacacgaga
      241 agaggagaag accgattttg ttggaaatcc cttgtttgtt caaatggttc acaatatagc
      301 aggtacgtca ttttggttgt gtaaaaaaga ggtgctagaa ttaattaatg gttttgagaa
      361 aatagattca catcaggacg gtgttgtttt attaaaacta cttgctcaag gataccaaat
      421 tgatatagtg cgagaattct tggtgaatta ctacgctcac agtaaagaaa acggtatcac
      481 tggagtgaca caaaaaacaa ttaatgcaga tgaagaatat tataattact gtaggaaata
      541 ttttaattta ttgagtttca acgagagaat attggttaca aagaaatatt attctttaaa
      601 cataaagcgg ttactattaa taggagacaa atgcaaggct ttaaaagtaa tcaagaaggc
      661 aagagaagaa aaaattttta acgaatttct ttttttgaaa tatatgttat tatatcattt
      721 tggttttttc tattgtatat atgacaacta tgttcaatta aaatttagaa agtgagaaac
      781 tattgtgtat actattataa aatcaaatat aaaaaaattt agtttattaa cgatatttat
      841 tgttgctggt caattattgc taatttatgc agcaactatt aatgctctgg tgttgaatga
      901 attaattgcg atgaatttag agcggttttt gaaattgtca atctaccaaa tgattgtctg
      961 gtgtgggata atattccttg actgggtagt gaaaaattat caggttgaag tgatccaaga
     1021 gtttaatcta gagattcgaa atagagttgc cacagacatc tctaactcta cctatcaaga
     1081 atttcatagt aaatcatcag gaacatatct ttcgtggcta aataatgatg ttcagacttt
     1141 aaatgatcag gcttttaaac aacttttttt agtaataaaa ggaatttctg gtactatatt
     1201 tgcagttgtg actcttaatc actatcattg gtcattgact gtagccacct tgttttcatt
     1261 aatgattatg ctacttgtac caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa
     1321 tttaactaac caaaatgaag cttttttaaa atctagtgag actatattga atggatttga
     1381 tgtgttagca tccttgaatc ttttatatgt attgcctaag aaaattaaag aagcaggaat
     1441 tttattaaag atggttatac aaagaaagac aactgtagaa acgttagcag gcgctattag
     1501 cttctttctc aatatttttt ttcagatatc tctcgttttt ttaacaggct atcttgcaat
     1561 aaaaggaata gtgaaaattg gtactattga agcaatagga gcactaacag gtgttatttt
     1621 tacagcgcta ggtgaattag gaggtcaatt atcctctatt attggtacga agcctatttt
     1681 tttaaaattg tattcaatta atccaattga gtcaaataaa atgaatgata tcgaaccaaa
     1741 tgaggtgaat agagattttc cgttatatga agcaaaaaat atttgctata agtatggaga
     1801 taaagaaata ttaaaaaact taaatttttg ttttcaacgt aatgaaaagt atttaatttt
     1861 aggtgaaagt ggaagcggga aatctacatt attaaaatta ttgaatggct ttttgagaga
     1921 ttatagtgga gaattgcgat tctgcgggga tgatataaaa aaaacctcct atttaaatat
     1981 ggtttcgaat gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga
     2041 taatatttta ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt
     2101 tggtttgagt gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg
     2161 gagattactg tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa
     2221 taagaaaata gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc
     2281 gattgaacgt aagatattag atagagagga tttgactgtc attattgtta cccatgctcc
     2341 gcatccggaa cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta
     2401 agaatatagg ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag
     2461 agaaaaaagt atactttaat gatattgagt tagaagtta
//
LOCUS       DAVLAQ010000116         2380 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000116 DAVLAQ010000000
VERSION     DAVLAQ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.116"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            158..496
                     /locus_tag="VXB71_002033"
     CDS             158..496
                     /locus_tag="VXB71_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452076.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            562..>2380
                     /locus_tag="VXB71_002034"
     CDS             562..>2380
                     /locus_tag="VXB71_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0452077.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFM"
BASE COUNT          852 a          320 c          411 g          797 t
ORIGIN      
        1 aaaggagggg tagttatgag atattttaac gactctagat accataacgg tgattaaaaa
       61 cctaaatata atcaattcat attaaagtaa tatggaggga ctaaaaagag actattattt
      121 aatcttcatc aaatatttaa attcaaggag aagtaaaatg aaaaaaagaa ttaataagaa
      181 agcatctgtt tttctagttg caagtgtttt cagttttagc tttgctacta cagctagtgt
      241 cgttaacgca gtaacggcac accctgctcc aagtcccatt attgatgtat gggaatatgg
      301 tgtaaatgat aactatggtt attcgaatta ctttgttagt tctccaagta atattggatc
      361 aaaatcttca gtaacgaatt tttggggaac agttaaagct caggataaaa aagattatgg
      421 atgggcatat tcaagtgcaa caaaatcttg gaacgatgtt cgcttaaatg catattggga
      481 ttattataga ttttaaaaat aatttatgaa aacaagagac ccaattataa gattgggtct
      541 cttgtaatat ggtaattgct tatgaaatta aaattatgta tcattggatt cttcttttgt
      601 ttgattgcta caattggtct ggtcactatt agtgataccg aaatccccat acctttacca
      661 attgatggag ctttttctat ccaaggaaaa agtaatcttt ctaataacga aatatacgaa
      721 atggttcgtg acttatcaaa aacggaaaag gttaccattt acaagccaat cgttcagagt
      781 tcgggtcagt tgaagtatgt aaattttgat gatgtaaata atgaacaatt aaagtcagca
      841 ccaatagtag ggatgtatta cacacttggg aaaatggatg tagacagttt gaaaccactt
      901 acgatgacgg gactacaaac agtctatatg gcttatcctt ggtatatagg aggaatatta
      961 caattcactg gaactttaag aatactgtta atgggttcaa tttatttaac tttattagtt
     1021 gttttatttg ttgttaggac gaggcagatc aaagaaggag tgatacgacg ttctttgggc
     1081 ttgcctatat acgacttaag aagagagtat ggcatttctc ttatttttga actgattatg
     1141 atggctttat tgatgatttc ttacagttct tttttgggta atggtttctt cacctatagt
     1201 tctaagttat ttttctctct gcttttaacg aattttatac tatttcaaat cattgatctt
     1261 attacttttg ttttattttg gttgacgatt cagattgaaa agcctattga aattattaaa
     1321 aacaaggcaa aaaacaagct tatttttgtc gtatggcttg ctattatttc gattatcatc
     1381 cttgtctcag gagttttttt acaagaaaca aagagtagtc aatctagtat taacatacag
     1441 atacagaatt tagtaccatg ggatacagta aaagactgga gaaggattga gttccttgga
     1501 attgaaagta actctactaa aaatagagaa gttaatgatt cagatggtca gtatctacag
     1561 atagttgctg ccttaaaaaa cttagatttc ttatatatag aacggtcttc agcatatgtt
     1621 ccagatttca tgaaaacttc acatgttata gaaaattttt ctaaacaatt agaaaatgac
     1681 gggataacga atccagaaat aaataaagag ttaatttata tcaaccaaac aggtgctaac
     1741 ctacaaaata aagtgaatgg aacaaactat catcttttag ataataagat agcaaccatc
     1801 tatattcctg agaagtggaa agaaaaccag aaatctattg agaatacagt tgtagcagaa
     1861 caatttattg gaacaaacta tacaagagaa cagcttgcag ttcaaataat tcctgatggg
     1921 gaaaaaattt tttattttaa tgaggatgct gataataatc ttaaaatgaa agatatttta
     1981 ccgctggcaa atgtagcaga tagcaaagat aatatagttg ttgtgttaga tacggacaaa
     2041 atgatggaaa ataataagtt ttctttggct agtaacatac tatataaatc tctttttagt
     2101 cctgaagcgg taaaaaaaat aaatgagatg actgtcctgt tgaatttctc aatgaatcca
     2161 gtagatgttt accaaattgt gaaattaaag attcaatcct tagagcacca aattttactt
     2221 tcacaaatct tgcagaagat aatttacagt attgtcttta tactcattta tcaatatgtc
     2281 caacttttta ttactctaaa acagaatgaa tatgtgaaaa aaatcatttt gggtctgtca
     2341 aaaacatata tagcaatttc aagtctcaaa tattttatga
//
LOCUS       DAVLAQ010000117         2365 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000117 DAVLAQ010000000
VERSION     DAVLAQ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.117"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..505)
                     /locus_tag="VXB71_002035"
     CDS             complement(<1..505)
                     /locus_tag="VXB71_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452078.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSS
                     GKFLDKHDRVFEGYPAYGGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWIS
                     DNAIYIKEFKNSDFNLVFLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQ
                     NEFADFVA"
     gene            complement(471..1436)
                     /locus_tag="VXB71_002036"
     CDS             complement(471..1436)
                     /locus_tag="VXB71_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0452079.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1554..1967)
                     /locus_tag="VXB71_002037"
     CDS             complement(1554..1967)
                     /locus_tag="VXB71_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0452080.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1964..2200)
                     /locus_tag="VXB71_002038"
     CDS             complement(1964..2200)
                     /locus_tag="VXB71_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0452081.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(2260..>2365)
                     /locus_tag="VXB71_002039"
     CDS             complement(2260..>2365)
                     /locus_tag="VXB71_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HEV0452082.1"
                     /translation="ADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
BASE COUNT          699 a          455 c          356 g          855 t
ORIGIN      
        1 gggctacaaa gtctgcgaac tcattttgga gggctagagg ggggaggata tatttctgat
       61 tttctaatgg tttttgagtt atctttggtt gacctgagaa atcagcaaat ttactaaaat
      121 caattacttt cattaattct aataaaaata caagattgaa atcggaattc ttaaattctt
      181 ttatatatat agcattgtca cttatccata ccttaccgtg ggtagttctt acattaccac
      241 aatatgcacc tacacgacca atgatgatag taggattatc aattaaatat tttcgacttt
      301 tccaagcaat gccatttcca ccataggcag gataaccttc aaaaactcta tcatgtttat
      361 caagaaattt tccacttgaa aatttaaaac actgttgtcc cgtttttact gcaaatttct
      421 tgttattatt taaaggatcc ccaaacatct cgttaaatcg ggatttgctt ttaagagatg
      481 aatttttggt gtgaatgctt gacattattt tgattgacca tggcataggc cagggttgtg
      541 tcaatcttgc tatgacctag cagtttttgg acttgttcga taggcatacc tttatcaatt
      601 gccttagtcg ctaaagttct tctgaactta tgtgggtgaa ccttttgtat gccgagtttg
      661 tctcctaact ttcttaagcg aatctctaca ccagcaattc caagtctctg ggcttttcca
      721 actagcgtta caaaaagagc agggtgacta tcttttctgt cgttaagata atttcttaaa
      781 tgaattttcg tccgagcgtc aaaatatact ggtctctcct tctttccttt accaaagaca
      841 acacactctc tgttttcaaa atcaatatct gaacgattca actgtacaag ctcccctaca
      901 cgcatacctg tcgatgctag taggtctatt attgccaaat ctctcaaatt ttcacagtta
      961 tcacgcataa tttccaaatg ttcatcagta taagtttcct tcacattttg ctcagtctta
     1021 attttcttta tccgtcgaat gggattttta atgatatatt cctcttgctc aagccaagca
     1081 aaaaaagaag acaatatacg cctaatattg tctaaatttg ccttactaca atccttttca
     1141 gactggtaat ttgctaaata actccttaaa tcatctgttg tgagttgtgt cacagactct
     1201 ttaatagcat taaacaagtt ttcaatcgtc ctctggtaat aacgaattgt ttttgagcta
     1261 cagccctcta cctgcttggc ggtaataaat agttgcaaca ggttattatt cgaatacttc
     1321 tgctgctttt ttccgtctac tagatgatgt tctaaactct ctctcaacgc tagtaattgt
     1381 tcattattta aaagaggtaa catttcttgc atgataattg taacttttga ttccataatt
     1441 tctcactttc ttattcatca ataaaaagag acaatatcag tttctgcatt acagaattct
     1501 aatattgtct gttcatttat tttcttgtgc tcattcaaat ccagcatact aggttacttt
     1561 ttgacctttt ctctaacaga atgttcagaa acccatttgg agtagcttgt cattttttca
     1621 tcagttaaag cttctactgc gatggttaca cacattttta ctgcttcttc taccgttaca
     1681 gaaaaacgat agccgtttaa ttgtaaaaat ttgaccaaaa cgaagaaagc agttctttta
     1741 ttagcattag caaaaacatg cttctttatc aattggacaa atagtatcgt tgctttatca
     1801 aaaattgttg gataaagaga cttcccaaag acaaattgtt ctggtaagtt cacaatcata
     1861 tttaaggcag aagaactaac tgtttgaatt ttctcatttg gagaataccg ttgaattgct
     1921 aaagcattta ttttttcaat ttgcttttct gtcagataga ttgtcatttt tccaccaaag
     1981 ctttgaaaac atcgtcgtat tcgtcaaata ttttatctaa atttaagtca aaggcatcat
     2041 cagatacata agaaacctgc tgccccaatt cttcaggagt aaagataatc tcaccacttg
     2101 gtaacaattt cgcttcgtat ttaacaccac ttggaatatt aaattcactt ggaatcgtaa
     2161 tggtgattga atttccttgt tttcttgttt ttactaccat ctgatttcct cctttgaagt
     2221 attataacaa atcattaccg taattacaat ggcagaatat cagccaaaat actcctgcat
     2281 cagagatttc ttcaaagttt caagttcttc cagagatttt tggattgcca attgtgattt
     2341 gtcgacctgg actacaaagt ctgcg
//
LOCUS       DAVLAQ010000118         2168 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000118 DAVLAQ010000000
VERSION     DAVLAQ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.118"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            43..915
                     /locus_tag="VXB71_002040"
     CDS             43..915
                     /locus_tag="VXB71_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0452083.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
     gene            915..1709
                     /locus_tag="VXB71_002041"
     CDS             915..1709
                     /locus_tag="VXB71_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452084.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          802 a          330 c          358 g          678 t
ORIGIN      
        1 ttcattttac ttatcggaga tgaaagttat tctttttcaa ctttgattaa agtcttaaat
       61 agtgaaactg ttcctggagc tagtttttcg attatggaaa ttagattacc aaaattatta
      121 gcaggaatta tagctggctg gtcttttgga ttggcaggat ttatctttca aactatgtta
      181 agaaatcctc ttgcaagtcc tgatataatc ggtgtcacaa gttcttcatc tattgcagcg
      241 gtcttttgca tattggtatt aaaaacaaat agtttaacta ctggaattat ttcaataact
      301 tgtggactaa catcatcttt aatattattt ttactagcta aaaaagatgg tttttcagca
      361 gcaagactga taatattagg tattggtttt caagctgtca caagagcagg cacctcattt
      421 ttattgttga aagtagcaag atatgaatta caagaagtta tgagatggct cagtggctct
      481 ttatctttta caaagttaga tgacatacct cttgttctaa tagtaagtat tattgctact
      541 atattagttt tattttttaa taaaagacta gaaattattg aacttggtga agaaatagca
      601 atcggacttg gagcaaatcc cgagctttca aggcttgttt taattttttg cgctgtatct
      661 ttaactgctt tttctacttc aattacagga ccaatagctt gtatatcttt tttagctggt
      721 cccatagcct taaatattgg caagaaaaga agcccaatat tagctggatt ggttggaatt
      781 ttactagttt tgttatcaga catattctct caaaatattt taccagctag atatccagta
      841 ggtgttgtaa ctggcttgtt aggttcacca tacttaatat acttactaat aaaaatgaac
      901 aggaggaata tataatgaaa ggtctgtggt caaataatct tacctgcggt tatgatgaaa
      961 aaataatctt ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg
     1021 ggtcaaatgg ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat
     1081 tagagggaga agtattgctt gataataaat caattaattc ttataaagaa aaagatttag
     1141 caaaacacat agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg
     1201 atcttgtaag ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg
     1261 accttgaaat aataaacaga tcaatggtta aggccaatgt tgaagatcta gcaaataacc
     1321 tagttgaaga actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc
     1381 aagatacaag tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa
     1441 tagaactatt agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga
     1501 ttttgcacga tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag
     1561 gtaaacttgt tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata
     1621 tctttaatct tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc
     1681 ctattggcaa gcaccatgtt aactcttaat aattgaatat tggaattcat ttaaaagtcg
     1741 caaattttga actgaccctc aaaagttagg ccaaaaaact aactaaagga ggtcagtttt
     1801 ttaatggcaa atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa
     1861 aaataggata tagagaataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa
     1921 gaaagtacaa cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc
     1981 tagaaaatac tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag
     2041 aaatatttat taccgaaaaa aaggggaaat cgagttaagt accaacaggc tcatctattc
     2101 caaaaagata tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg
     2161 gtatctta
//
LOCUS       DAVLAQ010000119         2006 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000119 DAVLAQ010000000
VERSION     DAVLAQ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.119"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>2006)
                     /locus_tag="VXB71_002042"
     CDS             complement(<1..>2006)
                     /locus_tag="VXB71_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0452085.1"
                     /translation="EGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANS
                     LEAGVNRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGS
                     IRQEILNATKDKANKSELTQTAEELSSKIASVHLGRRNLLKGTKELARYKPVSEYNGF
                     KVIRTVTGATRYQDSYVERTVIPTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSE
                     NSSGYKSRSSDGLSIIRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVE
                     ICAPAIFEGNLAGDWSPAYEDQDERVSAVESNFKQRADSLEAGVSRLTEGLRTKADIS
                     SLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELT
                     QTAEELASKIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGTGTAKTIDVSDSPAT
                     GFDKAIRLTSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSG
                     ISPIFTLKDENWTKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATS
                     SKEAPEDIEGQISTVESTFKQRANSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVK
                     SLETDTQNKLNQKLSQAEFEVRAGSIHQEILNATKDKASKSELT"
BASE COUNT          449 a          512 c          419 g          626 t
ORIGIN      
        1 tgcgtgagtt ctgacttgct ggctttatcc ttggttgcgt tcaggatttc ctgatggata
       61 gagccagctc gcacctcaaa ttcagcctga ctcaacttct gatttagctt gttctgcgtg
      121 tctgtctcaa gactcttcac agattgccgg atattctcag cagtcacatt gagtgagctg
      181 atatccgctt tagttctaag cccttcagtc agacggctta caccagcttc gagcgagttg
      241 gcacgctgtt tgaaggtcga ttcaactgtt gaaatctgac cttctatatc ttcaggagct
      301 tcttttgagc ttgttgccaa acttccgtct tccagctggg gcgcaagaac atctaaatat
      361 tctccgacct cagcatttac gagatacaca tagccaattg atgcgactcc agccctattt
      421 ctagcgctag taaacgatag ctttgtccaa ttttcatcct ttaatgtaaa gatgggcgaa
      481 atacccgaat tatcattgac ttgccaataa gtttgtagct tgaccttttg acctcttctg
      541 cctttgaccc aacaagacat cgtgtatgtg ccttgcgaga tataaaatcc atcttgagca
      601 atacctattt ggtctctagc attgcttgag gtcaatcgta tcgctttatc aaagccagtt
      661 gctggactgt ctgatacatc aatcgtcttt gccgtcccag tgcctgacgg tctaaaagta
      721 cctgatgccc acaatcctct ggctagcatc atgcgctttg taccccggat ataattccta
      781 cccccgacct gcacactcgc tatcttacta gccagctcct cagctgtctg cgtgagttct
      841 gacttgctgg ctttatcctt ggttgcgttc aggatttcct gacggataga gccagctcgc
      901 acctcaaatt cagcctgact caacttctga tttagtttgt tctgcgtgtc tgtctcaaga
      961 ctcttcacag attgccggat attctcagca gttacgttga gtgagctgat atcggctttg
     1021 gttctaaggc cttcagtcag acggcttaca ccagcttcga gtgaatcagc acgctgttta
     1081 aagttggatt cgaccgctga gacacgttcg tcttggtctt cgtatgctgg tgaccagtca
     1141 cctgcaagat ttccctcaaa aatggcaggg gcgcagattt caacccatac cccctcttta
     1201 ccgcctactt gagggccatg gcggccaatg atgaccgtct tggcttgatc tgttgcggtt
     1261 tgggtccatt taacccagca caactgccag tctgtcgaga gacggataat agacaagcca
     1321 tctgacgacc ttgacttata tccgctgctg ttttctgatg atacaaccgt gttaggattg
     1381 taaaaatgac agcgcacagg atagtcattt tcactggctc gtgcataaaa gatagctata
     1441 tactctgtcc cagccgttgg tataacggtt ctttccacat agctatcctg atatctagtt
     1501 gctcctgtga ctgttctgat aactttaaaa ccattatatt cactaaccgg cttgtatctc
     1561 gcaagctctt ttgtgccttt cagcagattt ctgcgcccta agtgcacact cgctatctta
     1621 ctagagagct cctcagctgt ctgcgtgagt tctgacttgt tggctttatc cttggttgcg
     1681 ttcaggattt cttgacggat agagccagct cgcacctcaa attcagcctg actcaacttc
     1741 tgatttagct tgttctgcgt gtctgtctca aggctcttca cagattgccg gatattttca
     1801 gcagtcacat tgagtgaact gatatcggct ttagttctaa ggccttcagt cagacgattc
     1861 acaccagctt cgagcgagtt ggctcgttgt ttgaaggtcg attcaactgt tgaaatctga
     1921 ccttctatat cttcaggagc ttctgaataa gaagtatcta catcgcttat ttcaaacttc
     1981 ggcatccaaa tccaaacggt tccttc
//
LOCUS       DAVLAQ010000120         1873 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000120 DAVLAQ010000000
VERSION     DAVLAQ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.120"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(159..1789)
                     /locus_tag="VXB71_002043"
                     /pseudo
     CDS             complement(159..1789)
                     /locus_tag="VXB71_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
BASE COUNT          568 a          369 c          395 g          541 t
ORIGIN      
        1 gtcaaatcga tttctaacaa tgttttagaa atagaggtgt actattctag tttcaatata
       61 ctatatatct gcagaatact ctttcagttt cattcagcct agtcttgctt aggaaaaagt
      121 aagaagccat ccaattatga tggatagctt cttggttatt agatttgttc tgcaaaaacc
      181 ttttcagcaa ggttcatagc gtggtctgat acacgagtgt agtgtgagat gatgtcgata
      241 aagttgaccc cagcttgtgt tgaacattcg cctttgttga ggcgtttgat gtgggttttt
      301 ctgagaacac gttctatctt attgattgct tcatgacgtt ctacaagact gcgtgctttt
      361 tcaatatcat tgttttccac actatccaga gcatctttga taaagtcact agtttggcgg
      421 taaacttcct ctaattcttt caaggcggca tcagaaaatt caacattttt ccgttgaaga
      481 tagtcagtca gattgagtag agcctccgtg tggtctccaa tccgttccaa atcacgggag
      541 gaatcaagga tattggtgag cacttcactt tctttttggc tgagagcttc gcttgaaagg
      601 gcaatgagat aacgtgttaa ttgctcatcg atggtgttaa ttgcttcttc ggttttatgc
      661 cctttttcag caactttttc atccaagtca atgatgtact tataggaaag gtcaaaggct
      721 ttagcagcgt agtttcctaa gtgcaagagc tcttttttag catttcctag agcgatagat
      781 ggggcttgtt tgatgaaatg ttcatcaaga tataagggtt cgtatttgac aacctcgtcc
      841 tctccaggaa taatcttggt tacaaagtaa gccagagctc cgataaatgg aaattggaca
      901 atggtgttgg taatattaag gttccgtgag caaaggcgat ggtcatttcc ggtgctagat
      961 ttagcgtagc ttcaaaccaa tgaatcagga cagtaaaagg aactagaaaa ataacgcaga
     1021 cgactgttcc gataacgttg aaggcaacat gagctcctgc tacccgttta gctgcaatat
     1081 tagcccctaa agaggcaatg atggctgtaa tggttgtccc gatattgtca ccaaatagaa
     1141 ctggcaaagc tccctgtagg tcaattagat tgccggcgta gaggttttgt aaaatcccaa
     1201 tggtagccga agaagcttga attagcaagg tcaagccggt accgacaaag acacccaaaa
     1261 caggattctt acttagctca atcatatagt ccttaaagac ctgtaaatcc ttgagtggag
     1321 ccattgcgcc gctcatgaga ttgagggcaa aaaagatacc accgacacca aagaggatgc
     1381 gtccgatatt attgactgtc cgatttttcg taaaaaagag acagacggca ccgataaaga
     1441 gcataggtag ggcatagtta cctaatttaa aaccgatgag aaaggatgtg acagttgtcc
     1501 caatattagc acccatgaca atcccgatag cctgacgtaa ggttaagaga ccggcactga
     1561 ccaggccgac tgtaataact gttacaccag aactagactg aattagagca gtcatcccaa
     1621 taccaaccag aactccaaag aaaggattac tagtatattt gtcaatgtaa aaacgaaggc
     1681 gatctccagc agcttgttgc aaaccgtctc ccatggtctt gatgctatat aagaatagcc
     1741 ccagaccacc taaaaagtga aataaaattt cctgccaatt aatggacatt tctttttcct
     1801 ccgaaaaata atcgcggaat atctcctatt ctattttaaa ggataaaagt aaatctaaca
     1861 agtgttaatg tca
//
LOCUS       DAVLAQ010000121         1803 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000121 DAVLAQ010000000
VERSION     DAVLAQ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.121"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..104
                     /locus_tag="VXB71_002044"
     CDS             <1..104
                     /locus_tag="VXB71_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0452086.1"
                     /translation="VQVDETDEVDGMRFSTFSTNRCGNWSAFSWENC"
     gene            400..1751
                     /locus_tag="VXB71_002045"
     CDS             join(400..841,841..1751)
                     /locus_tag="VXB71_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0452087.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
BASE COUNT          615 a          280 c          401 g          507 t
ORIGIN      
        1 ctgttcaagt tgacgaaaca gatgaagttg atggaatgcg atttagtaca ttcagtacaa
       61 accgttgcgg taactggagt gcttttagtt gggaaaattg ttaattcatt taaattgtaa
      121 actttaggga ttctctgaag ttatggatgt cgttccaata tgtgtacgtt ggaatgttag
      181 tgcttatatg gggggaacag aatcctctct tgattgaaga caagttagcc attaggctgg
      241 tttgtctctt tgtcaactgt agtgggttga tataatagta ttagtgagtg ggataaaagt
      301 ttcatttagt ttattcagta caaatttaac gggtcaagat ttattgaact gcaccccaat
      361 agttagacag aaaaaatcta acttttgggg tgttttatta tgaaattgag ttatgaagat
      421 aaagttcaga tctatgaact aagaaagcaa ggacaaagct tcaaacagct ttcaaaaaga
      481 tttggtgtgg atgtttctgg tctaaagtac atggtgaaat taattgaccg ttatggcata
      541 gaaatcgtta aaaaagggaa gaatcgtcac tattcttcta aattgaaaca agaaatgatg
      601 gataaagcct tactggaagg ttgttcacaa agaagtatta gtcttgatta tgccctccca
      661 aaccaaggaa tgctttcatt ttggccggca caatacaaga aaaacgggta tactattgtt
      721 gagaaaacaa gagggagacc agctaaaatg ggacgtaaac ggaagaagac ttgggaagaa
      781 atgacagaac tagaacgact ccaggaggag aatgaacgct tacggactga ggtggcctac
      841 ctaaaaaagt taaaagagtt agaggaaagg gacgaagccc tagagcgaga aaggcagaga
      901 cagttagaga aatggtttca ggaggatttc gactagattt tcttcttgaa acagcacgtt
      961 tagctcgctc gacttactat tatcagttga aacaactgga tggggttgat aaagataaag
     1021 agattaaaac cgaaattcag ggcattgata atgaacataa aggcaactat ggctatcgtc
     1081 gaatccattt agaactaagg aatcgtggtt ttgtggtcaa tcataagaaa gttcaacggt
     1141 tgatgagaat tcttggttta acggctcgaa ttcgccgtaa acggaagtat tcttcctacc
     1201 aaggagagat tggcaagaaa gcagagaatc tcattcaacg ccagttcgaa gcatcgaggc
     1261 caatggaaaa gtgctataca gatgtgacag agtttgccat tccaaatagc acacagaaac
     1321 tctatttatc accagtttta gatggtttta acagtgaaat cattgcttat catctttcta
     1381 cttcgcccaa cttagaacaa gtgaagagta tgttagaaca agcctttaca gagaaatact
     1441 atgagaatac gattctccat agtgaccaag gctggcaata ccaacacgat tcttatcatc
     1501 ggttcctaga gagtaaggga attcaagcat ccatgtcacg caagggcaac agcccagaca
     1561 acggcatgat ggaatctttc tttggcattt tgaaatcgga gatgttttat ggttatgaga
     1621 agaactttag atctttagaa aaccttgaac aagctattgt ggactacatt gattactaca
     1681 acaacaaacg aattaaggta aaactaaaag gacttagttc tgtgcagtac agaactaaat
     1741 cctttggata aattatttgt ctaatttttt ggggtcagta cagtattaaa taccatgatc
     1801 tta
//
LOCUS       DAVLAQ010000122         1788 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000122 DAVLAQ010000000
VERSION     DAVLAQ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.122"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            360..836
                     /locus_tag="VXB71_002046"
     CDS             360..836
                     /locus_tag="VXB71_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0452088.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            836..1597
                     /locus_tag="VXB71_002047"
     CDS             836..1597
                     /locus_tag="VXB71_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0452089.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELFFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          658 a          241 c          345 g          544 t
ORIGIN      
        1 aaacaacact ttattgaggt attggatacg ctttgctaat agcctaataa tcacatgtgg
       61 agtgttgcta caacgaaaaa ggcgataatc cttgatttca aactatttta taagcatttt
      121 gtctttgtag ataaaggcaa ttttgacaat aaaaatccta aaaggtgaat cgttatagat
      181 gtatttgtag atatcgtttg cgcatcgaaa aaattaatac aagaataaat atttatggct
      241 ctttaggtga cttttataga agtaaagttt aggatagaaa aacaagaaat aatgcaccat
      301 ttttggtgca ttatgctttt ttatgctata attgaattat aaaaataaag gagtttgcca
      361 tgattggaaa gaacataaaa tccttacgta aaacacatga cttaacacaa cacgaatttg
      421 cacggattgt aggtatttca cgaaatagtc tgagtcgtta tgaaaatgga acgagttcag
      481 tctctaccga attaatagac atcatttgtc agaagtttaa tgtatcttat gtcgatatcg
      541 taggagaaga taaaatgctc aatcctgttg aagattatga attgacttta aaaattgaaa
      601 ttgtgaaaga aagaggtgct aatctattat ctcgactcta tcgctatcaa gatagtcagg
      661 gaattagcat tgatgatgaa tctaatcctt ggattttaat gagtgatgat ctttctgatt
      721 tgattcatac gaatatctat ttagtagaaa cttttgatga aatagagaga tatagtggct
      781 atttggatgg aattgaacgt atgttagaga tatctgaaaa gcggatggta gcttaatgga
      841 aatccaagat tatactgata gtgaattcaa acatgcttta gcaaggaatc ttcgttcact
      901 gacaagagga aaaaagtcca gtaagcaacc tatagcgatt ttgcttggag gtcaaagtgg
      961 tgccggtaag actacaattc atcgtattaa acagaaagaa tttcaaggaa atattgttat
     1021 catagatggt gatagttttc gttctcagca tccacactat ttagaactgc agcaagaata
     1081 tggcaaagac agtgtagaat ataccaaaga ttttgcagga aaaatggtag agtctttagt
     1141 aacaaaattg agtagtttgg gatacaatct tttgatcgag ggaactttac gaacaattga
     1201 tgttccaaag aaaacggcac aactcttgaa aaataaggga tatgaagtac aattggcctt
     1261 aattgcgaca aagcctgaat tgtcgtatct aagtactctt atccgttatg aagaactgta
     1321 cattatcaat ccaaatcaag cacgcgcaac tccaaaagaa catcatgatt tcattgtaaa
     1381 tcatctagtt gataacacac gaaaattgga agaactagct atctttgaaa gaattcaaat
     1441 ttaccaacga gatagaagtt gtgtatatga ttcaaaagaa aatacaactt cagcagcaga
     1501 tgttcttcaa gagttattct ttggggagtg gagtcaggta gagaaggaga tgttgcaggt
     1561 gggggaaaag agacttaatg aattacttga aaaataaaca attgatattt ttaggagaat
     1621 agaaatgaga gggtttaata acaagataaa gtctgtttat caagaactaa caaattccaa
     1681 agagaaattc ggtagctttc acaagacttt aattcatttg catacacctg tttcttatga
     1741 ttacaagcta ttttctaatt ggactgcaac gaaatataga aaaattac
//
LOCUS       DAVLAQ010000123         1555 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000123 DAVLAQ010000000
VERSION     DAVLAQ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.123"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(129..216)
                     /locus_tag="VXB71_002048"
     tRNA            complement(129..216)
                     /locus_tag="VXB71_002048"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Ser,seq:gct)
     gene            complement(223..296)
                     /locus_tag="VXB71_002049"
     tRNA            complement(223..296)
                     /locus_tag="VXB71_002049"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(260..262),aa:Ile,seq:gat)
     gene            complement(332..402)
                     /locus_tag="VXB71_002050"
     tRNA            complement(332..402)
                     /locus_tag="VXB71_002050"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(368..370),aa:Gly,seq:tcc)
     gene            complement(422..494)
                     /locus_tag="VXB71_002051"
     tRNA            complement(422..494)
                     /locus_tag="VXB71_002051"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(459..461),aa:Phe,seq:gaa)
     gene            complement(498..571)
                     /locus_tag="VXB71_002052"
     tRNA            complement(498..571)
                     /locus_tag="VXB71_002052"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(535..537),aa:Met,seq:cat)
     gene            complement(582..671)
                     /locus_tag="VXB71_002053"
     tRNA            complement(582..671)
                     /locus_tag="VXB71_002053"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(633..635),aa:Ser,seq:tga)
     gene            complement(682..755)
                     /locus_tag="VXB71_002054"
     tRNA            complement(682..755)
                     /locus_tag="VXB71_002054"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(719..721),aa:Ile,seq:cat)
     gene            complement(769..842)
                     /locus_tag="VXB71_002055"
     tRNA            complement(769..842)
                     /locus_tag="VXB71_002055"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Met,seq:cat)
     gene            complement(848..921)
                     /locus_tag="VXB71_002056"
     tRNA            complement(848..921)
                     /locus_tag="VXB71_002056"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(885..887),aa:Pro,seq:tgg)
     gene            complement(937..1010)
                     /locus_tag="VXB71_002057"
     tRNA            complement(937..1010)
                     /locus_tag="VXB71_002057"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(974..976),aa:Arg,seq:acg)
     gene            complement(1020..1105)
                     /locus_tag="VXB71_002058"
     tRNA            complement(1020..1105)
                     /locus_tag="VXB71_002058"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1069..1071),aa:Leu,seq:taa)
     gene            complement(1113..1184)
                     /locus_tag="VXB71_002059"
     tRNA            complement(1113..1184)
                     /locus_tag="VXB71_002059"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1150..1152),aa:Gly,seq:gcc)
     gene            complement(1207..1279)
                     /locus_tag="VXB71_002060"
     tRNA            complement(1207..1279)
                     /locus_tag="VXB71_002060"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1244..1246),aa:Thr,seq:tgt)
     gene            complement(1298..1379)
                     /locus_tag="VXB71_002061"
     tRNA            complement(1298..1379)
                     /locus_tag="VXB71_002061"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1343..1345),aa:Leu,seq:tag)
     gene            complement(1385..1457)
                     /locus_tag="VXB71_002062"
     tRNA            complement(1385..1457)
                     /locus_tag="VXB71_002062"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1422..1424),aa:Lys,seq:ttt)
     gene            complement(1482..1554)
                     /locus_tag="VXB71_002063"
     tRNA            complement(1482..1554)
                     /locus_tag="VXB71_002063"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1519..1521),aa:Asp,seq:gtc)
BASE COUNT          427 a          434 c          339 g          355 t
ORIGIN      
        1 gaaatttgtc ctttctcgag cttagctttt cttcaaccca ctacagttga caaagagcct
       61 taagtttacg gatctgaagt tttattgtct ctaaaaacaa aaaagagagt tacaaactct
      121 cattaaaacg gagaataagg gattcgaacc cttgcgccag ttacccgacc taacgattta
      181 gcaaaccgtc ctcttcagcc tcttgagtaa ttctccaatt aatgggcacg agtggactcg
      241 aaccaccgac ctcacgctta tcaggcgtgc gctctaacca cctgagctac gcgcccaagt
      301 taaaaaactt ggtaatttga acaaagttca aagcgggtga cgagaatcga actcgcgaca
      361 acagcttgga aggctgtagt tttaccacta aactacaccc gcataaatac tatcaataaa
      421 atggcgcgag acggaatcga accgccgaca catggagctt caatccattg ctctaccaac
      481 tgagctaccg agccttattg cgggagcagg atttgaacct acgaccttcg ggttatgagc
      541 ccgacgagct accgagctgc tccatcccgc gttaatataa aaggaggatg tgggattcga
      601 acccacgcac gcttttacac gcctgacggt tttcaagacc gttcccttca gccggacttg
      661 ggtaatcctc caatattcaa atggaccttg taggacttga acctacgacc actcggttat
      721 gagccgagag ctctaaccag ctgagctaaa ggtccgacaa gatcattata gcggcgaagg
      781 ggatcgaacc cccgacctcc cgggtatgaa ccggacgctc tagccagctg agctacaccg
      841 ccatgaatcg ggaagacagg attcgaacct gcgacacctt ggtcccaaac caagtactct
      901 accaagctga gctacttccc gagttaaata gaaaaatgca ccctagagga gtcgaacctc
      961 taaccgcctg attcgtagtc aggtactcta tccagttgag ctaagggtgc tccatattat
     1021 gccgaggacc ggaatcgaac cggtacgatc gttaccaatc gcaggatttt aagtcctgtg
     1081 cgtctgccag ttccgccacc ccggcctctc taagcgaacg acgggattcg aacccgcgac
     1141 ccccaccttg gcaaggtggt gttctaccac tgaactacgt tcgcactgtt ttcttctatc
     1201 taaaaatgcc ggctacatga cttgaacacg cgaccctctg attacaaatc agatgctcta
     1261 ccaactgagc taagccggct catttgttat atcttaatgc gggttaaggg acttgaaccc
     1321 ccacgccgtt aagcgccaga tcctaaatct ggtgcgtctg ccaattccgc caaacccgca
     1381 tatatgaccc gtactgggct cgaaccagtg acccattgat taaaagtcaa ttgctctacc
     1441 aactgagcta acgagtctaa aataacttgc gttatcttaa acggtcccga cgggaatcga
     1501 acccgcgatc ttcgccgtga cagggcgacg tgataaccgc tacactacgg gacct
//
LOCUS       DAVLAQ010000124         1549 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000124 DAVLAQ010000000
VERSION     DAVLAQ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.124"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            69..809
                     /locus_tag="VXB71_002064"
     CDS             69..809
                     /locus_tag="VXB71_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452090.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            812..>1549
                     /locus_tag="VXB71_002065"
     CDS             812..>1549
                     /locus_tag="VXB71_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452091.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQS"
BASE COUNT          508 a          201 c          300 g          540 t
ORIGIN      
        1 agatacactg atatatataa attggaaaat ggaacacttt tcaaaattaa gtgattggag
       61 gcaagaatat ggataaagat tatatattaa aagtgaaagg gctgtatcat caatttttac
      121 taggaaataa taaaacgttg caagtgctga aaaatgtttc tctttctgct tcgagaggag
      181 aatttataag tattctagga attagtggtt ctggaaagtc aactttatta aaatgtattt
      241 ctagtttgct tgaaccaaca agtggggaag taattttaaa tggaatcaac ccctataaaa
      301 tcagaaatgc aaaattgtca agtataagac gtaacgaagt atcttttata tttcaagcat
      361 acaatttaat accttccctg ccggtaatag aaaatatagc acttcctttg cgattatcac
      421 aaaaaaaatt aactattaaa aatgtagaaa acttactcaa aagaatgaag tttaatgctg
      481 gcttaaacga ttttgttgga actctgtctg gtggagaaca acagaaggtt gctatagcta
      541 gagcggttat tgctgatagt gatataatat ttgctgatga gccaactggg gctttagaca
      601 gcgtttctcg tgaagtaatt tttgaattat tgagagagtt agtaggggcg ggtaagtgtg
      661 taattatggt aacgcacgat atagaattgg cctcgaaaac tgatcgtgca ttaatattga
      721 aagatggaaa aattttcaaa gaacttcata gacctagcgg ggaagagttg tataaaatct
      781 tagaggtaca atcaactacg gaggaataga gatgctcaga ttagtttact atcaattttt
      841 acataataag aaacaatggt taggcgtttc accagtaatt tttgtttcga gtttagttat
      901 gggattggct gttaatgggg taattaatgt tgagaataat tcgcaagtat ttgtcggact
      961 tccagatcct aaaccaattt ttatgtttcc gatagtattc ggaggagtaa cattattctt
     1021 tgtgctctct aacataataa atatgttggt tgaaattttt agagatgatt acgaacttct
     1081 ggaggtgttg ggagcaagtc tccttcaact atcatttctt gtggggggac agatttttat
     1141 catttcctcg attattagtt ttattgcata tctatgctct atatttgtta cgtcaaatta
     1201 ttattatttt ttacaatact ttttcgggga aaatatatta cctgatatcc aatttcaaac
     1261 gagtgctgtt ggatgtatca ttacagtagt gttgatttca tttttagcct ttctaagtgg
     1321 ttgcttttat acgttcaaga agattagaaa taggaagagt tctaaaataa ggcatgttct
     1381 ttcaatagta aaaagaatac tgctattggc tggttttagt gttatctggt tgctttcttt
     1441 gcaacaaatt ttccaagata gcacaatttt agcgaaggcc cagataatat tcaatattgt
     1501 aatcttagat attgtgatta tttatcaatt atctcctttt atacagtca
//
LOCUS       DAVLAQ010000125         1515 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000125 DAVLAQ010000000
VERSION     DAVLAQ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.125"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            26..1372
                     /gene="gdhA"
                     /locus_tag="VXB71_002066"
     CDS             26..1372
                     /gene="gdhA"
                     /locus_tag="VXB71_002066"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0452092.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          467 a          295 c          321 g          432 t
ORIGIN      
        1 aatatgacaa taaaaggaga acgatatgac atctgctaaa gaatatatcc aaagcgtgtt
       61 tgaaactgtg aaagctcgta acgggcacga ggctgaattc ctccaagctg ttgaagaatt
      121 tttcaacact ttagaacctg tatttgaaaa acaccctgag tatatcgaag aaaatatctt
      181 ggcacgtatt actgagcctg agcgcgtggt ttctttccgt gttccttggg ttgaccgtga
      241 tggaaaaatt caagtaaacc gtggttaccg tgttcaattc aactcagctg ttggaccata
      301 caaaggtgga cttcgtttcc acccaactgt aaaccaaggg atcttgaaat tcctcggatt
      361 tgaacaaatc tttaaaaatg tcttgactgg acttcctatc ggtggaggta aaggtggatc
      421 agacttcgat cctaaaggta aaacagatgc tgaagtgatg cgcttctgcc aaagcttcat
      481 gactgaattg caaaaacaca tcggaccatc acttgacgta cctgctggtg atatcggtgt
      541 tggtggacgt gaaattggtt acctttacgg tcaatacaaa cgtcttaacc aatttgatgc
      601 tggtgtcttg actggtaaac ctcttggatt tggtggtagc ttgattcgtc cagaagcaac
      661 tggttacggt ttggtttact atactgaaga aatgctcaaa gctaacggta acagctttgc
      721 tggtaagaaa gtcgttattt caggttctgg taacgttgct caatatgctc ttcaaaaagc
      781 aactgaactc ggtgcaactg ttatttctgt ttctgactca aatggttatg tcatcgatga
      841 aaatggtatc gacttcgatc ttttggttga tgttaaagaa aaacgtcgtg ctcgtttgac
      901 tgagtatgca gctgaaaaag caactgcaac ctaccacgaa ggtactgtat ggacttacgc
      961 tggaaactat gacattgctc ttccatgtgc cactcaaaac gaaatcaacg gtgaagcagc
     1021 taaacgtttg gttgctcaag gcgttatctg tgtatctgaa ggtgccaaca tgccgagcga
     1081 ccttgatgcc atcaaagttt acaaagaaaa tggtatcttc tacggacctg caaaagctgc
     1141 caacgctggt ggtgtagccg tttcagctct tgaaatgagc caaaacagtc ttcgcctctc
     1201 atggactcgt gaagaagttg atggccgtct caaagacatc atgacaaaca tcttcaacac
     1261 agctaaaacg acttcagaaa catacggtct tgataaagac taccttgcag gagctaacat
     1321 tgctgccttt gaaaatgtag caaatgccat gattgcacaa ggtattgttt aagatttatt
     1381 tactcaatcc tcaatcacta cgattgggga tttttagctt gaattaaaaa attggaaaat
     1441 ctaattaaat aaaatgaaat gaaataaaaa ctgaacaaat tgattgcgga attcaaacca
     1501 atttctaaca tattt
//
LOCUS       DAVLAQ010000126         1426 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000126 DAVLAQ010000000
VERSION     DAVLAQ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.126"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>1426
                     /gene="pcpA"
                     /locus_tag="VXB71_002067"
     CDS             <1..>1426
                     /gene="pcpA"
                     /locus_tag="VXB71_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0452093.1"
                     /translation="LAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGN
                     IGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIV
                     YYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFDFSELEEIELPASL
                     EYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRL
                     TTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFN
                     KNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAFYGNLELKELILPD
                     NVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTEFSVKKDT
                     FAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGW
                     VKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT          549 a          196 c          240 g          441 t
ORIGIN      
        1 ttttagcagc atatgtccct aatgaaccaa tcctagcaga tactcctagt tcggaagtaa
       61 tcaaagagac taaagttgga agtattattc aacaaaataa tatcaaatat aaggttctaa
      121 ctgtagaagg taacataggc actgttcaag tgggtaatgg agttactcct gtagagtttg
      181 aagctggtca agatggaaaa ccattcacga ttcctacaaa aatcacagta ggtgataaag
      241 tatttaccgt tactgaagta gctagtcaag cttttagtta ttatccagat gaaacaggta
      301 gaattgtcta ctatcctagc tctattacta tcccatcaag cataaaaaaa atacaaaaaa
      361 aaggcttcca tggaagtaaa gctaaaacta ttatttttga caaaggtagt cagctggaga
      421 aaattgaaga tagagctttt gatttttctg aattagaaga gattgaattg cctgcatctc
      481 tagaatatat tggaacaagt gcattttctt ttagtcaaaa attgaaaaag ctaacctttt
      541 cctcaagttc aaaattagaa ttaatatcac atgaggcttt tgctaattta tcaaatttag
      601 agaaactaac attaccaaaa tcggttaaaa cattaggaag taatctattt agactcacta
      661 ctagcttaaa acatgttgat gttgaagaag gaaatgaatc gtttgcctca gttgatggtg
      721 ttttgttttc aaaagataaa acccaattaa tttattatcc aagtcaaaaa aatgacgaaa
      781 gttataaaac gcctaaggag acaaaagaac ttgcatcata ttcgtttaat aaaaattctt
      841 acttgaaaaa actcgaattg aatgaaggtt tagaaaaaat tggtactttt gcatttgcag
      901 atgcgattaa acttgaagaa attagcttac caaatagttt agaaactatt gaacgtttag
      961 ccttttacgg taatttagaa ttaaaagaac ttatattacc agataatgtt aaaaattttg
     1021 gtaaacacgt tatgaacggt ttaccaaaat taaaaagttt aacaattggt aataatatca
     1081 actcattgcc gtccttcttc ctaagtggcg tcttagattc attaaaggaa attcatatta
     1141 agaataaaag tacagagttt tctgtgaaaa aagatacatt tgcaattcct gaaactgtta
     1201 agttctatgt aacatcagaa catataaaag atgttcttaa atcaaattta tctactagta
     1261 atgatatcat tgttgaaaaa gtagataata taaaacaaga aactgatgta gctaaaccta
     1321 aaaagaattc taatcaggga gtagttggtt gggttaaaga caaaggttta tggtattact
     1381 taaacgaatc aggttcaatg gctactggtt gggttaaaga caaagg
//
LOCUS       DAVLAQ010000127         1375 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000127 DAVLAQ010000000
VERSION     DAVLAQ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.127"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(151..339)
                     /locus_tag="VXB71_002068"
     CDS             complement(151..339)
                     /locus_tag="VXB71_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452094.1"
                     /translation="MRLGGSLGQRRENEIFFGLLAILFIKPIIGIVKFFWMIISFAVQ
                     LLFYKILFKILDWLFKLI"
     gene            complement(299..481)
                     /locus_tag="VXB71_002069"
     CDS             complement(299..481)
                     /locus_tag="VXB71_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452095.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(483..1262)
                     /locus_tag="VXB71_002070"
     CDS             complement(483..1262)
                     /locus_tag="VXB71_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452096.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT          455 a          295 c          200 g          425 t
ORIGIN      
        1 aacatatata ctgcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa
       61 tgattttact gcttatatta taccatatgg agagagatta aaaaactagc agtggagttc
      121 ctgctagctc tctgcgactt ggattaccat ctagataagt ttaaagagcc aatccaatat
      181 cttaaacaat atcttgtaaa acagcaattg aactgcaaag gaaatgatca tccaaaagaa
      241 tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa aaaaaatttc
      301 attctctctc ctctggccta atgagccacc gagccgtatc cattagctta tctgcaataa
      361 aaagttttcc cagaccaaca acgacatggt cagctttctt tatcgttttc atcactttta
      421 caccttgcac ggtcaaaaag taattaccat aaattttatc aaaagctttg ataggattca
      481 tattactctc ctttaatgat ttcagcctct tttcggattg tttcaacatc ttcttgatat
      541 tgaacttcac tatagttgac tagcttggat aattctttct gcaagctttc ccccattggt
      601 ttcatagttg caaaggttaa accacctgca atgataccac ccaagatagg aataaatttc
      661 cctattcctt tggccagccc tcccttggta agattcacac caaatatttt taagactttt
      721 ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat taggcactgt tttcattacc
      781 tgtttggcaa ttgttatacc accagcacat agcaaagcag cggttccatt cacccctaac
      841 attacgccta gataaagcaa gagggtattt tgagcatctt cactcaactc ctcgcgtgaa
      901 gcccaaagat cctcataacc ataaatataa cctaattctt gagccaattt cagagagaaa
      961 gcataaaatt gagccacatc agctggaatg gtaattgcca tagcaagccc tccagctaat
     1021 cctgccaaaa cagaagtccc actcgctaat aatacattgt cccgaataca agcattagct
     1081 acacgatcta atatttcttg agatagaaga gtcgttgtac cttgttccaa taaggtagga
     1141 atatcttttg gatccaattc tttggaaaac ttatccacta aaaatttcga acgatcaacc
     1201 ttaacaacag gtagtttcac cacttgttgc aatacttgca tagctaagtc ttgttcagcc
     1261 atatacaaac tccttatttc ttttttacac cttatcatat tatatttcct acaaaaaaag
     1321 cattttctaa ttagataaca ttaaaaaata cagaacccct tttttatagt aaaat
//
LOCUS       DAVLAQ010000128         1284 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000128 DAVLAQ010000000
VERSION     DAVLAQ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.128"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..240
                     /locus_tag="VXB71_002071"
                     /pseudo
     CDS             1..240
                     /locus_tag="VXB71_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
     gene            294..530
                     /locus_tag="VXB71_002072"
     CDS             294..530
                     /locus_tag="VXB71_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452097.1"
                     /translation="MNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKL
                     PKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            514..810
                     /locus_tag="VXB71_002073"
     CDS             514..810
                     /locus_tag="VXB71_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452098.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            982..>1284
                     /locus_tag="VXB71_002074"
     CDS             982..>1284
                     /locus_tag="VXB71_002074"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HEV0452099.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDPIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI"
BASE COUNT          540 a          136 c          227 g          381 t
ORIGIN      
        1 ttgaggattc aaagggtaaa ataaccgttt taaataacca attttataat ttatccggta
       61 agtatatatc attcatcaaa tctaatgcaa acgggaaaga acctgttata cgtgatagcg
      121 atggtaattt caatattgta acggagaatg ggctttacaa aattgtaaca aataatttaa
      181 gtgataaaaa cgaaaaagaa aaaaacaaag aggaaaaaca atctaattca aataatgtaa
      241 ttgatagtaa ccagaagaac ggagagttta actcaagtaa agataataga caaatgaatg
      301 acaagatcga caataaacaa gataataaga cagaagaagt aaactataaa atagttggag
      361 atggcagaga aactgaaaat catattaata aatctaaaga aatagtagat gtaaaacaaa
      421 aattaccaaa gactggttcg aacaagatta tggaactatt cttaacagtg acaggaattg
      481 gtttactttt gacactaaaa gggttgaagt attatggtaa agataaataa aatttgttcg
      541 atacaaggaa gttccgtaga aaatgaggat attgtaggtt cacaaaatca gtatttttgg
      601 attattggtg gagctacaga tttatataat tctaaagagg agataggtta ttcagtctca
      661 gaagttgtac atattttatc agaaagtttg tcggttaatt gtaaagaatc aaaaactctt
      721 aaacaaatat ttgaaactgc tttactcgag gttaaagatg aaatcggttt aaactcatat
      781 gaattaacag agtataataa aatgaaataa taataggaca aatcaatcag gacagtcaaa
      841 tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa tatactatat
      901 tatcgcttac caacatttgc ttttatattt gctaaacttt cagaaaaaaa gttggagtat
      961 atgatgctag gtgactgcgt catgttagta aacgaaatgg aaataacgga tcatagagta
     1021 gataacttat ttgaaaaagg gaaaaatgag ataaaagatc caattggtac aaatagtgtt
     1081 ttaaataaaa aaattatttt acaaaaaatc agaaaattat ctaatcaacc gagtgggtac
     1141 tggataggtt cgttggatga gagattttta gaccatgcta ttattaatca aatagatgtt
     1201 actagtgaac aaattgtttt aatgagcgat ggcttttatg aattctatca aaataatcaa
     1261 aataaaactt ttgaagagtt aatt
//
LOCUS       DAVLAQ010000129         1168 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000129 DAVLAQ010000000
VERSION     DAVLAQ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.129"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..1026
                     /locus_tag="VXB71_002075"
     CDS             1..1026
                     /locus_tag="VXB71_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0452100.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1016..>1168
                     /locus_tag="VXB71_002076"
     CDS             1016..>1168
                     /locus_tag="VXB71_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0452101.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDD"
BASE COUNT          455 a          162 c          197 g          354 t
ORIGIN      
        1 atgaaaaaca aattttttct aatagctatt ttagctatgt gtatagtttt tagcgcttgt
       61 tcttctaatt ctgttaaaaa tgaagaaaat acttctaaag agcatgcgcc tgataaaata
      121 gttttagatc atgctttcgg tcaaactata ttagataaaa aacctgaaag agttgcaact
      181 attgcttggg gaaatcatga tgtagcatta gctttaggaa tagttcctgt tggattttca
      241 aaagcaaatt acggtgtaag tgctgataaa ggagttttac catggacaga agaaaaaatc
      301 aaagaactaa atggtaaagc taacctattt gacgatttgg atggacttaa ctttgaagca
      361 atatcaaatt ctaaaccaga tgttatctta gcaggttatt ctggtataac taaagaagat
      421 tatgacactc tatcaaaaat tgctcctgta gcagcataca aatctaaacc ttggcaaact
      481 ttatggagag atatgattaa aattgattca aaagccttag gtatggaaaa agaaggtgat
      541 gagttaatca aaaatactga agctcgtata tccaaagaat tagaaaaaca tccagaaatc
      601 aaaggaaaaa tcaaaggaaa aaaagtatta tttactatga ttaatgctgc agatacatca
      661 aaattctgga tttatactag caaagatcca agagcaaatt atttaacaga tttaggtcta
      721 gttttccctg aatcattaaa agaatttgag agtgaagata gttttgcaaa ggaaatttct
      781 gcagaagaag caaataagat aaatgatgct gatgtaatca taacttatgg tgatgataaa
      841 actcttgaag ctttacaaaa agatcctctt ttaggtaaaa taaatgcaat taaaaatggt
      901 gccgttgctg taattccaga taatacaccg ttagcagcct catgcactcc aacaccactt
      961 tcaataaact atactattga agaataccta aatcttttag gaaatgcatg caaaaatgcg
     1021 aaataaaaaa caaataaacc taggcataat ttttgtaatc tgcctaggtc ttcttattac
     1081 aatatttttg tcattaaagc ttggaacaaa agaaattaat atcagagatt ttttagcagc
     1141 ttttggaatg ggcaatacaa atgatgat
//
LOCUS       DAVLAQ010000130         1094 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000130 DAVLAQ010000000
VERSION     DAVLAQ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.130"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..159)
                     /locus_tag="VXB71_002077"
     CDS             complement(<1..159)
                     /locus_tag="VXB71_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0452102.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKF"
     gene            complement(172..921)
                     /locus_tag="VXB71_002078"
     CDS             complement(172..921)
                     /locus_tag="VXB71_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0452103.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          379 a          211 c          116 g          388 t
ORIGIN      
        1 aaacttcata agctcttcat ttttagatgg aagaatgccc ttttttaaat tatttatttt
       61 tacagaatct atatcatatg caacaacttt atatttagat gcaaatagta acgcgtaggc
      121 cagcccaaca tgccccaaac caattactgc tatattcata aaactacttc cttatttctt
      181 aatccaaaat ctaatagaat aagctgcccc attccttaaa tacaactctt taatattgtt
      241 taaaagtttt tcaactgatt tccagattat caaaatctga gatttatagc acaatattga
      301 tgatattcta tcaatataat gtttttcatc aagttcctct tgatacattt ttaattcttt
      361 agtttttccc atataactaa ccatactact atcacttaca tatgggaagt cctcataata
      421 tattacttta taacgcataa attcaagcgc ccttccaata ctattcacaa aaacatgatc
      481 aacatggtca ccaagtgaaa gcggacaata tacgacacat ttgtcgtcta aatgcattaa
      541 cagctctttt atgatatcat tctttaatgt gtcctcattt tttaattcac tatagatatg
      601 acggtataga aaattgccat ttctatcttt cctatagaga cattcatagt acgataagtg
      661 tctaaaatca cactgtagac gttcacaagc taacctgtct tctttcttcc tttcttcaat
      721 cggatatttc ccaaggttac acaacttatg aaattgctta gcagagggct gtagctgttg
      781 gctcaaaggg taaccagaaa atatagtaat aacaagtaca atttctcctt ctgaagttaa
      841 ttttgaaata taatcaccac aggaaaaaat tgcgtcatct aaatgtggag ataaaaagat
      901 atacttagta ttgttactca taaccattcc ctctacaatt tatctaaaaa ctcactaagt
      961 gtctgattaa attccacatc atcaaaaaaa ttcaccttat tcttaataat gaatatttcg
     1021 ttaaataaac atatatataa atatttcaat atcctttcaa tatcatcctc taaattctcc
     1081 tcaatatttt gtat
//
LOCUS       DAVLAQ010000131         1075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000131 DAVLAQ010000000
VERSION     DAVLAQ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.131"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            119..>1075
                     /gene="pavB"
                     /locus_tag="VXB71_002079"
     CDS             119..>1075
                     /gene="pavB"
                     /locus_tag="VXB71_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0452104.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAY"
BASE COUNT          365 a          197 c          223 g          290 t
ORIGIN      
        1 taatataagt gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt
       61 taatttcagg agattatact agagtcatca aataaagaaa gactctaagg agaatcctat
      121 gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt
      181 tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg
      241 tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa
      301 agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg
      361 cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga
      421 aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc aagaaaatcc
      481 agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg ggacacaagc
      541 aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga
      601 cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc
      661 tggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct
      721 attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc
      781 tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg
      841 caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta atggtactca
      901 aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa
      961 tctagttgct actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt
     1021 cgaaaaagct gttaaagata acgttaaaga cagtatcgat gttccagcag cctac
//
LOCUS       DAVLAQ010000132         1059 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000132 DAVLAQ010000000
VERSION     DAVLAQ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.132"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..151
                     /locus_tag="VXB71_002080"
     CDS             <1..151
                     /locus_tag="VXB71_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0452105.1"
                     /translation="LTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYME
                     RYRDR"
     gene            117..431
                     /locus_tag="VXB71_002081"
     CDS             117..431
                     /locus_tag="VXB71_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452106.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
BASE COUNT          442 a          135 c          195 g          287 t
ORIGIN      
        1 tttaacttca attattaggc aagctttaaa aaatactgaa tataaagatc aaatatctag
       61 cacagtattg ccagatatca aaattaaatt accgatagac agtagaggta ctccagattg
      121 gaattacatg gaaagatata gagatagata aagagagaga gggagagata gataaaaagt
      181 ccacccccat tttttatgga gaattcaaaa atgtaaggtt aagcaaagaa gaatataaaa
      241 atctaaaaga aaaattaaac tcacacacag atataatgat aaataaacta tccagataca
      301 tggaaagcag tggtaagacc tatcaaaacc actatgtgac aatcttaaaa tggtatgaag
      361 aagataaaga caaactaaga cagaaaggtt taaataaaaa aatgaattat gatgtaggag
      421 aatctttata gataaaaaga ggtggaaagg cactattaaa gactttaagt ctaaaaaggt
      481 atcaaagtat gccagagata aaaaaatata aatatgacac tttaaaggcg attagaaaat
      541 taaagaaatg ctagaagact tttagatgac agttaccaag agggtctaat tttcactgct
      601 acttatgcag tgggaattgg acctttttat ataagcaaat tctatttcaa aattggttac
      661 caagaaagac ttcttttcac tgttaagtat aagagggtaa tttatagaat tttgttacat
      721 caagataaat attttctgat ggtcaaattt taaaaagatt aataactttc gataaatttt
      781 gaaccttaac aattgaatag accaagacaa gacgttaatt atttttggag cgtaataacc
      841 tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa agttctgcta aacaaaaaga
      901 aagtgagcga taagtaagag tttgaatata gggagggata ccctatccgc tatgaagaaa
      961 atgaggataa tgatacttct aaggttgaag ccggctcatc cggaatagag gcggaggtga
     1021 gattcctatg ttgctaatcc aaagcacttg tcaatgtca
//
LOCUS       DAVLAQ010000133         1030 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000133 DAVLAQ010000000
VERSION     DAVLAQ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.133"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            56..970
                     /locus_tag="VXB71_002082"
     CDS             56..970
                     /locus_tag="VXB71_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEV0452107.1"
                     /translation="MYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKT
                     TFGLTGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLP
                     LINTLVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKN
                     IYKVTRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTF
                     CHGSMAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGV
                     TGIAYTFLRYIALNQNDKKIVIPSLLEI"
BASE COUNT          359 a          127 c          191 g          353 t
ORIGIN      
        1 tatacctgtt aattttaaag gttctaaatg gtgtcttgaa caaacgggta atgatatgta
       61 taggggtaga gctggaatat tactgtttat gtactatgta aaattattga aagataaatc
      121 atcatatact caactgtaca ataaaatgtt atctgcaatt ccgccatctg tttctttatc
      181 taagaccaca tttggtttaa ctggggatat aggatatttc attgttctat ccattataga
      241 ggattacgat acaaatactc tcgcatgctt aaattatata aagagtgttt taactgagct
      301 tgaaaagact gattttgcaa gtgtttcaaa caagtctgac tatattaatg gtcttctacc
      361 tttaattaat acactggtaa gatattatag gagaggaata gagaaggaac gtgttctaag
      421 gctagtatta agtttaggtg atacgctata taatgatgta agcgagagag ataatagtaa
      481 ttttggatat agttttggcc atggactatc aggtgtaatt tttacattaa aaaatattta
      541 taaagtgaca agacttaaaa aatataaaga attaatttta caactagttc ctagggagaa
      601 aatcaaaatt cattctttga agtggtgtag tggagaattt gggacattag ttaatcatcc
      661 ccaaagtgtt ccagagggaa ttgtagctag tttagataat gatacatttt gccatggaag
      721 tatggccata ataaattttt acatcgacta catgaaagaa atggatacta gtatggaatt
      781 ggagtcttta ttgtgtagtg ttgtaatgaa taaatcaaaa gaaggagagt atcgtatcgt
      841 ccaaacaagc aatttcccag atttttcttt gtatacaggt gtgactggta ttgcttatac
      901 ttttttaagg tatatcgcac tgaatcagaa tgacaaaaag atagttatcc cctcattact
      961 tgaaatctag cttaatttat agttttgttt ctaaaataga ggtgtccact cattaagcaa
     1021 tataaaaata
//
LOCUS       DAVLAQ010000134         1019 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000134 DAVLAQ010000000
VERSION     DAVLAQ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.134"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(78..140)
                     /locus_tag="VXB71_002083"
     CDS             complement(78..140)
                     /locus_tag="VXB71_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEV0452108.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            220..>1019
                     /locus_tag="VXB71_002084"
     CDS             220..>1019
                     /locus_tag="VXB71_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV0452109.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKIEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGE"
BASE COUNT          367 a          165 c          138 g          349 t
ORIGIN      
        1 tactccagaa taaccgtgtg ctaaacctgt tactgttata ttatctaatt gtgaaataca
       61 ataattaata cactttttta aatgatgata atatccatca ccaaaaccaa aatcggtaaa
      121 aattttgaaa ttttcttcat acttggactt cctttccgtt tttatttatt gtacaataaa
      181 taaaaacgga tttaattttt gttgggaaaa tgggaaatta tgaaatcaaa acttggcatc
      241 acacttagaa aagttcgtaa aggaaaacaa attagtctat gctctgtagc agatgaacat
      301 ctttcaaaat cacaaatatc tcgttttgaa cgtggggagt cagagatatc ttgtattcga
      361 ctaatcaata ttttagacaa attacatatt actttggatg agttccttgt tttacacaat
      421 gacgactata ccagttccga atcatttgct aatctagtac agtacattcg taagcaatat
      481 tcatcacaaa gtatcaataa tatagcatgt ctactttctg atacttctga ttacactcta
      541 aattcttttg agaaaacaat ggtaaaatct attttacaca caatggattc gaacatcatt
      601 ccatcagatg aagagcttct tcatctgaca gactatcttt tcaaaattga aaaatggggc
      661 tattatgaaa tcattttatt aggtaactgt gtacgcacaa ttaactacaa ctcctacttc
      721 ttattaacta aagagatgtt aaataactat atttactcat ctctgaataa aactaataag
      781 cagattgtct ctcagcttgc tattaattgc ttcattctaa gcattgataa ggaagaattt
      841 tctaattgct cctatttaat tagtaagata aagacattgt tggataatga actaaacttt
      901 tatgaacaaa cagtttttct ctatgcaact ggttactttg aatttaaacg ttgccaatca
      961 accagtggaa ttgaaaaaat gaaacaagcc atacaagtct tcgatatttt aggagaaaa
//
LOCUS       DAVLAQ010000135         1011 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000135 DAVLAQ010000000
VERSION     DAVLAQ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.135"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>1011
                     /locus_tag="VXB71_002085"
     CDS             <1..>1011
                     /locus_tag="VXB71_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEV0452110.1"
                     /translation="KGEKGDQGERGLTGAQGAKGEKGDQGEQGLQGRDGEQGPKGEDG
                     KNPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTVIFY
                     YDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITI
                     TQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQ
                     TTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTWEPA
                     GNIKGPKGDKGADGAKGEKGAQGERGLTGAQGAKGADGAAGRDGRDGRDGKDVLNGKV
                     NPE"
BASE COUNT          415 a          166 c          259 g          171 t
ORIGIN      
        1 aaaggtgaaa aaggggacca aggtgaacgc ggtctaaccg gagcacaagg tgctaaaggt
       61 gaaaaagggg accaaggtga acaaggtctt caagggcgtg atggtgaaca aggaccaaaa
      121 ggagaagatg ggaaaaaccc aacagttaaa gtaactgatg gtcaagatgg aacgcataca
      181 attacaatta acgatggtaa aggtggtata actactacag tagtaagaga tggatttgat
      241 ggtgcaagcc ctcttgtttc tactcataga aatgaagcag ataaaacaac aactgttatt
      301 ttctattatg atctaaatga taataatcaa tttgatgaag gagatacaaa acttaaagaa
      361 gttgttatcg cagatggaaa acaaggacca aaaggtgaca aaggtgataa cggaaaagat
      421 ggattcacac cagaagtaac agttacagat aacaataacg gaacacacac catcacaatc
      481 acacaaccag acaacagacc atcattaaca acaatcgtta aaaacggtga agatggaaaa
      541 acaccaaaag tcaaagcaga acgagatgat gcgaagaaac aaacaacatt aacattctac
      601 attgacaaag atggagatgg aagttacaca gcaggaaaag acgagttagt tcaaacaaca
      661 gtagttaaag acggacaaga cggagctgca ggagcatctg gacgtgatgg aaaagaagta
      721 ttaaacggaa aagtagaccc aacaacagaa ggtaaagatg gagacacatt cgtaaataca
      781 caaacaggag atgtattcgt taagaaaggt aacacttggg aaccagcagg aaacatcaaa
      841 ggaccgaaag gtgacaaagg tgcagatggt gccaagggtg aaaaaggagc ccaaggagaa
      901 cgcggcctga ctggagcgca aggagctaaa ggtgcggatg gagcagcagg tcgtgacgga
      961 cgtgatggac gtgacggtaa agacgtgttg aacggcaaag ttaacccaga a
//
LOCUS       DAVLAQ010000136          999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000136 DAVLAQ010000000
VERSION     DAVLAQ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.136"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            238..837
                     /locus_tag="VXB71_002086"
     CDS             238..837
                     /locus_tag="VXB71_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452111.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVLSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     VGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
BASE COUNT          364 a          144 c          190 g          301 t
ORIGIN      
        1 ttaatatttg gagaagagga tggccatctt ctccattttt atgtgcagag ttatagtgac
       61 ttgatgctgg gaaagtacac tgtgactgct aatactcaat gaaaatcaaa gtgcaaacta
      121 ggaagctagc cgcaggctgt acttgagtac gtcaaggtga agctgacgtg gtttgaattt
      181 gattttcgaa gagtataaaa cattcctaga agttgctttg atttccctaa tctatttatg
      241 caaattttat gttattttac tataacagtt gttgctaagc caaataatag tggggaagtt
      301 catttagacg taagcattga agataatcag ggaggtagtg ggcataattt cagttctgtt
      361 tcaagtagct cacaaacagc taaatatgaa gaaactggtt ataataacaa tttatcatta
      421 tatacaacga ttgataaaac gtctgatgca acagctcttt tgaaattaaa gttgaataat
      481 gttgataatc aacctgctac tgaagttctt agttcaggaa ttactgtaaa attaaatgct
      541 aaagataatg ctggaaactg gacaagtgct tcgaataaaa aagaaataac agtaaaaatt
      601 gtttctgcta aaccgacata tccagacaaa atcttagtga aaaatcctga taatataaaa
      661 gatacagaaa aaaatgccat tattgaaaaa ttgaaagagg caaataaaaa ttatccagta
      721 ggagctccaa cctttgctaa aggtgaagga gagcatgcaa atgatattgt agcaacttat
      781 tcagatggta caacttatta tgtaccgtta aatgatgtga caaaatatgc gaggtagtgg
      841 ctgtaccact cacttattca cctccccgtg atttgtagta gtgataggct ttctaactat
      901 tattataaaa caaaataaag agcacaacac tttttcattc tgtgttgtgc cttgagtgaa
      961 acgaaaggaa tgaattataa atatgaaaag tatagtcac
//
LOCUS       DAVLAQ010000137          981 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000137 DAVLAQ010000000
VERSION     DAVLAQ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.137"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            56..967
                     /locus_tag="VXB71_002087"
                     /pseudo
     CDS             56..967
                     /locus_tag="VXB71_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          318 a          171 c          210 g          282 t
ORIGIN      
        1 taatttatag aaatatttta gcagctaagg tgtactgtta tagattcaat acactataga
       61 ctgtaatcaa acaacgattt ggcgaaatgt aaaaaaatat gaggagttcg aactcgactc
      121 tctccttcaa gaaacacgtg gtggccgtaa ccatgcatat atgacgattg aggaaaagaa
      181 agtctttctt gcccgccatt tgaaggctac agaggcagga gaatttgtta caattgatgc
      241 cttatttcag gcttataaaa aggagttagg tcgttcctac acacgtgatg ccttctatca
      301 actgttgaag caccatggtt ggcgaaatat tatgccacgt ccagaacatc ctaggaaagc
      361 agacgctcaa accattgtcg cgtctaaaaa taaaatctca attcaagaag aaaagaaagc
      421 gctttaaaag cagtagacgt tttcgtaagg ttcgcttgat gtaccaagat gaggctggtt
      481 tcggtagaat cagtaaactg ggatcttgtt gggctccaat aggagtaggt ccacatgtcc
      541 atagtcacta tatacgagaa tttcactatt gttatggagc tgttgatgcc catacaggcg
      601 aatcattttt cttaatagct ggtggatgta atactgagtg gatgaacgcc tttttagaag
      661 agctttcaca agcttatcca gatgattatc ttttactcgt tatggacaat gctatatggc
      721 ataaatcaag taccttaaag attccgacta atattggttt tacctttatt cctccataca
      781 caccagagat gaacccattg aacaagtgtg gaaagagatt cgtaaacgtg gatttaagaa
      841 taaggccttt cgaactttgg aagatgtcat gaatcaactt caagatgtca tacaaggact
      901 ggagaaggag gtgataaagt ccatcgttaa tcggagatgg actagaatgc tttttgaaag
      961 cagatgagta ttatatgcaa t
//
LOCUS       DAVLAQ010000138          939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000138 DAVLAQ010000000
VERSION     DAVLAQ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.138"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            390..614
                     /gene="pneA1"
                     /locus_tag="VXB71_002088"
     CDS             390..614
                     /gene="pneA1"
                     /locus_tag="VXB71_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEV0452112.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            621..809
                     /gene="pneA2"
                     /locus_tag="VXB71_002089"
     CDS             621..809
                     /gene="pneA2"
                     /locus_tag="VXB71_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEV0452113.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
BASE COUNT          351 a          108 c          176 g          304 t
ORIGIN      
        1 aataattctt tatggtaata aacaaaaaaa aaagttaaaa attacataaa aatacttgac
       61 taaataaaat atatctgtta gaataaaaac aaggaaaaag aaaggggttt cattgcatga
      121 gaaaaaaacg tggaattaaa aaattagtta catttgcatt gctaggtgtt tttatgttta
      181 gtaatacaat tccttaccaa cagtttattc agaagaataa acaattggag attcgagtgt
      241 aatcgcaaaa gaagtccaat ggtcttgatg ttgggaaggc tgattaaaac ccgatatttt
      301 gcacgagaat gagagaatta taatttatct gaaaaaacga aaaatataga gcaacttatt
      361 taacttttta taaggaggag ttattactta tgaccaactt taattcaaac gaaaaatttt
      421 gtggaaaaag tttaaaatca ttgtctgctg atgaaatgag tttaatttat ggtgcatctg
      481 atggtgcaga gccacgttgg acgcctactc ctattatttt gaaatcagct gcagctagct
      541 cgaaagtatg cattagtgca gctgtttctg gtattggggg gctagttagc tacaataatg
      601 attgtttggg gtaaattaaa atgaaaaatg attttgtaat cggaaagagt ttgaaagaat
      661 tatctcttga agaaatgcaa ttggtttatg gtggcacaga tggtgctgac cctagatcaa
      721 caattatatg ttctgctaca ttaagtttta ttgcatcata tttggggtca gctcagactc
      781 gttgtggcaa agacaacaag aaaaaataaa atattcaatt ttaaaaataa aagttgctct
      841 ttattttcct ctctcgtaac taataatttt gagagaggtt tttttttaaa acaatagtaa
      901 gtcgtatagg tttgaggtaa gtaaatgaaa tataaaatt
//
LOCUS       DAVLAQ010000139          899 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000139 DAVLAQ010000000
VERSION     DAVLAQ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.139"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            96..585
                     /locus_tag="VXB71_002090"
                     /pseudo
     CDS             96..585
                     /locus_tag="VXB71_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536889.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            601..>899
                     /locus_tag="VXB71_002091"
     CDS             601..>899
                     /locus_tag="VXB71_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452114.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNT"
BASE COUNT          309 a          105 c          156 g          329 t
ORIGIN      
        1 tatatggtgt tgactacaat caagaaagat ttagaagttt gatccaagag ttagatttga
       61 ctcagtctat taataaaaaa gtaaagacct attctttggg tacaaaacaa aaattagctt
      121 tgcttctaac tctcgttacg gaacctgata tattgatttt agatgaaccg actaatggtt
      181 tagatattga atcatcacaa atagttttag cggttctaaa aaaaattagc tttaaatgaa
      241 aacgtgggaa ttttaatatc gagtcataaa ttagaagaca ttgaagaaat ttgtgagagg
      301 gttcttttct tggagagcgg gcttttgaca tttcaaaaag taggaaaaga tagtcataat
      361 ttcttgtttg agatagcttt ttcatcagct acagatagag acattttcat taccaaacaa
      421 gaatttgggg atattgttca ggaagaggga ttgagaatta ctatgtctgg gaatattcaa
      481 aatagtgagc tttttaaatt ttttaacgaa aactctatta aagtagttga ttttgaaact
      541 aaaaaagaga cgcttaaaga tatttaccta aatcgttcaa aataaaggaa ggttataatc
      601 atgaaattaa ataaacagaa gaatcggatg atttacgtct tgtctaattt tctatatgcc
      661 atctcagttt ccattattta tgctttgaat ggcattgtgt tactagtcat agtaagtaaa
      721 ttgggtattc caggtgattt aggattagat tttatagtag ctattgtagt caatacaatt
      781 ttgttagtcc tgttttattt tctattatct tacatttttt atttatacaa attgaaaagt
      841 ggcttggtat ttggtatttt agtagcttta ctactcttta tccctaatat attaaatac
//
LOCUS       DAVLAQ010000140          897 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000140 DAVLAQ010000000
VERSION     DAVLAQ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.140"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..803
                     /locus_tag="VXB71_002092"
                     /pseudo
     CDS             1..803
                     /locus_tag="VXB71_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            796..>897
                     /locus_tag="VXB71_002093"
     CDS             796..>897
                     /locus_tag="VXB71_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0452115.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQS"
BASE COUNT          326 a           81 c          190 g          300 t
ORIGIN      
        1 gacagtgata acatgccatg gatgggttga atataactta aaaaagaaat tcttgactta
       61 ttttgatttt tggacatatt ctatgggaga tgcttttatt tgtgtatctg aaactatgaa
      121 aaaaagattg gagagtataa taaaaaaata agaagatagt tgtaataaat aacggaatta
      181 atgtatcaaa tagcgattta gatgtagtag gtgttcaaga ctttaaaaaa gaattttgta
      241 ttccaaataa caaaaaaatc atttgttatg ttggaaggtt ggatccagaa aaaaggccgg
      301 atagattcct tgaatttgca gaaaaattat ttttagtcag agaagatgtg atttttatta
      361 tggctggaaa tggtagtatg tgggctgctt tgaaagaaaa aatttgccat ttgaaatgta
      421 gagataattt caggttactt ggtgaaatct atccagctac tatagtttac caaatatcgg
      481 atttattgta tattccttct gatacagaag gaatacctat gtgtgtttta gagtcaatgt
      541 cacaaggaac tccggtttta gctagtaatg ttggcgggtt aagtgaaatt attgaacata
      601 gggttgatgg atttttattt gagaaggaag atgttgaggg agtgtgtgct tgtgctaatt
      661 ttttactcaa tgattctgag tatttgaaat atataggtga gaatagtaaa tcaaaaataa
      721 gaaaacattt ttctgtgcaa aaaatgtttg tagaaaccat gagagtatat gatgaattat
      781 tagagaagag tagtcatgga taggaatata gatcaagaat tagtaagtat tataatacca
      841 acacataata ggtatgaatc tctgattaga gctgtgaaaa gttgtttaca tcaaagt
//
LOCUS       DAVLAQ010000141          862 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000141 DAVLAQ010000000
VERSION     DAVLAQ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.141"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(38..853)
                     /locus_tag="VXB71_002094"
     CDS             complement(38..853)
                     /locus_tag="VXB71_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0452116.1"
                     /translation="MFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGASLSVVIG
                     LSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSMALSSFV
                     SFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNALAMGD
                     EMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDIRTMT
                     ISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVNN"
BASE COUNT          304 a          168 c          129 g          261 t
ORIGIN      
        1 ttttttcttt tttgaatacc tataattaaa ttttgcatta gttattaacc cctctatttt
       61 tcatagttac ataaataagt actggacccc cgattattgc agtaattatc cctacttcaa
      121 tttcacctgg tttacctaac atacggccga ttatatcaca tataagcaag agctctgcac
      181 ctataaaaga tgaagaaatg gtcattgtgc gtatatcttt gcttataaat aagccacaaa
      241 agtgaggaac tataagacct acgaagccaa taggtccacc aattgcagta atacttgaac
      301 ataaaagcac acttgcaatt attgcaagtg atcttatcct attaacatta actccaagac
      361 caacagccat ttcatcaccc atagctaaag cgtttaaatc tgatgaaata aatatagcta
      421 tcaagtgacc taaaattata aaaggtagta gtgtagatat agaagataat gtagctgctc
      481 caaggctacc tatttgccaa aatctaaatt tgtctaagac gttattattc ggtaaaatta
      541 aaaaacttac aaaactgctt aaagccatac taacacaagt tcctgataag gcaagtttta
      601 taggggtaag gcctgctttt ccgcttacag caatcgcgta tacaaaaatt gcacttacta
      661 agccaccaat gattgcaaaa cttatatggc ttatgcttga tgaaattcct aaaaaagaaa
      721 gaccaattac tacactaaga cttgctcctg tgtttatacc gagtatacct ggatcagcta
      781 ttgggtttct agtaactgat tgcatcaata caccgcttat ggcaagacta gaacctgcta
      841 aaattgcaaa aatagttcta gg
//
LOCUS       DAVLAQ010000142          855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000142 DAVLAQ010000000
VERSION     DAVLAQ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.142"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..366
                     /locus_tag="VXB71_002095"
     CDS             <1..366
                     /locus_tag="VXB71_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0452117.1"
                     /translation="SLIDNKTVYDNLSLITKDKKTITDVLEKVGLSSDYLHQKIYELS
                     GGQAQRVAIARMLMKPRKIILADEPTGALDGEIGKEIIRLLLNETAEDKYVIIATHDP
                     AVYNEVDVIIDMKDIGYKV"
     gene            363..>855
                     /locus_tag="VXB71_002096"
     CDS             363..>855
                     /locus_tag="VXB71_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452118.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEK"
BASE COUNT          339 a          108 c          168 g          240 t
ORIGIN      
        1 tctttaatag ataacaaaac agtgtatgat aatctgagcc ttatcactaa agacaaaaaa
       61 acaataactg acgtacttga aaaagtagga ctgtcaagtg actatttaca ccaaaaaata
      121 tatgaattgt ctggagggca ggctcaacgt gtagctattg ccagaatgtt aatgaaacca
      181 cgtaaaatta tcttagcaga tgaacctaca ggagctttag atggtgagat tggaaaagaa
      241 attattcgtt tactattgaa tgaaacagct gaagataaat atgtcattat agcgacacat
      301 gatccagctg tctataacga agttgatgtg ataattgaca tgaaagatat agggtataag
      361 gtatgaaaaa gaaaatttat attgctttga tctttgtaac tggggtactc gccattttct
      421 tttttggaaa acaaatgatt acaaaagaaa atatcaataa gccaacggta gagttaacaa
      481 tctatacgct ttcttctagt gatacagaaa aatggaataa agtgagacaa gtagaaacgg
      541 aagaagctat atacttcata actgtgaaag aagtatcatc ttcagaagaa gtattttcaa
      601 acatcattgc aaatggagct gctacggggt tcggagttcg tgaagaagaa gtgaagaaat
      661 tcaataatgg tttaggagac accatagagg actctaagca taataaacta attgaaatag
      721 aattttttac tttttctgat gatggcgcgg gatttgtggt agcaaacttt gactacggta
      781 aagaagagtt gaattctcag aaaaaagata taaaagaatt atataaaaaa atatatgaat
      841 cttttaaaga aaaga
//
LOCUS       DAVLAQ010000143          848 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000143 DAVLAQ010000000
VERSION     DAVLAQ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.143"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..591)
                     /locus_tag="VXB71_002097"
     CDS             complement(<1..591)
                     /locus_tag="VXB71_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0452119.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISI"
     gene            751..>848
                     /locus_tag="VXB71_002098"
     CDS             751..>848
                     /locus_tag="VXB71_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452120.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTV"
BASE COUNT          301 a          134 c          110 g          303 t
ORIGIN      
        1 tatacttatc cattcatttg cctttgcttt aaagaaaaaa tcagcggcag gagcgtccat
       61 cttacaattt aatatttcca ttgccactct ttctaaggcc tttgtaagta ttatttgatt
      121 cggttgaagc aaggttgaat aaaaagattc tggattaatg ttaatagatg ctaaatgttt
      181 ttctattagc tcttttttaa aaccaatgga aacagcaaga taacaacaat tctcgtgtaa
      241 taaaaaaaca aaatcatctt ttatattatc aaaatcaaaa gtacataaag agtttgcggt
      301 aatagtttga tacggattaa acttttctcc gtttgcactg acaatgtaac ttgaataaat
      361 tgaaacatag tctgacatac tataagtgct attttgaact acttcctctt tgatataaaa
      421 atcatgtata tcgataatga agctgcctcc ttcataaaac caatataggc cttctgcata
      481 agttgaattc tcttttttcc aacaaaatgt atgacctgca cttgaatact tctcattgtt
      541 tttacattca tctactttca tataatcttt tacaaaatca taatatgaca taacacacta
      601 tcccttttag acaatattcc aattagcctt attaattcaa aactattgta ttagtaatta
      661 taacagatgt ataatagaaa agcaatgata gatattatca attaagcgaa tttatatcta
      721 aaagggatat taaagaaagg agatatgctt atgaagattt acaaaaaact atttgcttat
      781 gtccaagata agaaatatct tggggttttg gccataattt tttctgctat atctgctcta
      841 cttacagt
//
LOCUS       DAVLAQ010000144          789 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000144 DAVLAQ010000000
VERSION     DAVLAQ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.144"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            23..>789
                     /locus_tag="VXB71_002099"
     CDS             23..>789
                     /locus_tag="VXB71_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV0452121.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQF"
BASE COUNT          249 a          166 c          130 g          244 t
ORIGIN      
        1 acaactcatt agaaagaatc atatggaaca attacatttt atcacaaaac tgctcgatat
       61 taaagaccca aacatcaaga ttctagatat catcaatatg gatacccaca aagaaattat
      121 cgctaagctg gattatgagg ctccatcttg ccctgattgt ggaagtctaa tgaagaaata
      181 tgactttcaa aaaccgtcta agatccctta cctcgaaaca actggtatgc cttctagaat
      241 tctccttaga aaacgccgtt tcaagtgcta tcactgttca aaaatgatgg ttgctgagac
      301 tcccctggta aagaaaaatc accaaatccc tcgtatcatc aaccaaaaaa ttgctcaaaa
      361 gttaattgaa aaaatttcta tgactgatat tgcccatcag ctggccattt caacttcaac
      421 tgtcattcgc aagctcaatg actttcactt tgagcatgat ttttctcggc ttccaaagat
      481 tatgtcttgg gatgagtatg ccttcactaa gggaaagatg agtttcattg cgcaagattt
      541 tgataatctt aatattatca ctgttcttga aggcagaaca caagctgtca tccgaaatca
      601 ctttcttcgc tacgatagag ccgttcgttg tcaagtgaaa atcattacga tggatatgtt
      661 tagtccttac tatgacttgg ctaaacagct ttttccgtgt gctaaaatcg ttctagatcg
      721 tttccatatt atccaacatc tcagccgtgc catgagtcgt tttcgtgttc aaattatgaa
      781 tcagtttga
//
LOCUS       DAVLAQ010000145          772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000145 DAVLAQ010000000
VERSION     DAVLAQ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.145"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..218
                     /locus_tag="VXB71_002100"
     CDS             <1..218
                     /locus_tag="VXB71_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452122.1"
                     /translation="DEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVS
                     GVVYEISRKQDDRLLNVLLLELRGHDD"
     gene            211..>772
                     /locus_tag="VXB71_002101"
     CDS             211..>772
                     /locus_tag="VXB71_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452123.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLITFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFIN"
BASE COUNT          284 a           93 c          127 g          268 t
ORIGIN      
        1 aagatgaaga aaacctatta ataaaagaat ctatagattt ttattttgat aatgtcgttt
       61 ctcaggtcat caaaccagaa ttaagtacgg atttgaatac tatgaataca ttttctttta
      121 tgctaggagt atctggagtt gtctatgaaa tatctcgaaa acaagatgat agattactta
      181 atgttttatt actggagtta agaggacatg atgactagaa aagtacctaa tattgagcaa
      241 atgtctcaaa tagaatgtgg tttatgttgc tgcttgtcca tactacattt ctataaaagc
      301 aaagagacat tactagattt aagacgtgat atagaaaaag ggagagatgg ttatagtata
      361 ggtgacttga aacagttatt gaataaacga aattttgata ctggctcata tcaagttaaa
      421 gatgtaaata aaattagtga acttccgtta ccattaataa cattctggga taatcaacat
      481 tatgtagtta tttacaaagt aaaaaagaat aaggtctata taatggatcc ttctaaagga
      541 tatataaatt atgagtttaa ggagttttca aaacatttta gtaatatagt actgctatca
      601 tttcctaacg aaaattatca atctttgaag tcgcagtttc cttctccatg gataagagta
      661 ttctctagtt tttcaaaggt aaaaggtcga ttgattttga cgttactatt ttcaataata
      721 agttacttaa taatactttc cgtaccagta atgacttcaa agtttattaa tt
//
LOCUS       DAVLAQ010000146          769 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000146 DAVLAQ010000000
VERSION     DAVLAQ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.146"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..409)
                     /locus_tag="VXB71_002102"
     CDS             complement(<1..409)
                     /locus_tag="VXB71_002102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452124.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIK"
BASE COUNT          322 a          121 c           91 g          235 t
ORIGIN      
        1 tttttatata aataagtata tttttaattc ccctatcctt caataatcgg tataaaagat
       61 actgactcat accttgatac caaataaaat tcggtatttc aataagagca tgaggtaata
      121 ttccttttat tgtagctact attccaatca tctgaccaga tatacccaat tgtattccta
      181 aagatagcaa atcaaaaagt tgcaataagg gcgaaatcgg aaaacagaat agatatagca
      241 aaaaatttgt agaatttgcc tgtaaaactg tcaatgtaaa ttgtaattcc agtttcggag
      301 gtatagtagc aaaagtctca ttttttaata taaagcttaa aagtaaacct agtaaaaaac
      361 agactataca aaataacaca tagtaaatca gaaaaccact ttttctcatc taatgccccc
      421 tactaaaatt acaaatatta tcagaaaaca atataaaacc agaaaactcc atctcaataa
      481 actaactgta cctttaatta aaaatagagc tttcttataa tagacatagg ctataaaata
      541 attgaatgga atcaataaca aattcaacaa aatacttttt atatcattac tataacttgt
      601 caccggaatc aaacataaca acaatgaaaa ttgtaagaaa gagattaaat gcgtcaacat
      661 cattagttgt gcattcttaa aaaagaaatt cattttagaa tgattaagag cagataattg
      721 aagtaaagct agatctaccc caattgagga tttatgattc cctattatt
//
LOCUS       DAVLAQ010000147          766 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000147 DAVLAQ010000000
VERSION     DAVLAQ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.147"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>766
                     /locus_tag="VXB71_002103"
     CDS             <1..>766
                     /locus_tag="VXB71_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452125.1"
                     /translation="TQEIDVPYDIPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDG
                     INWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGA
                     IHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLP
                     PLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDP
                     NDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          291 a          107 c          133 g          235 t
ORIGIN      
        1 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggttttct
       61 acattggttg aaattgtcag aggtggctct ccacgaccaa tcaaagatta tcttacttct
      121 gaagtagatg gaataaattg gataaaaata ggtgatactg aaaagggtga aaagtatata
      181 aataatgtta aagaaaaaat caaaaaatca gggcttaaca aaactagatt tgtaaaaaaa
      241 ggtacatttt tgttaactaa ttctatgagt tttggtagac cttatatttt gaatgttgat
      301 ggtgcaatac acgatggatg gttggctatt tcgaactatg aaaactcatt aaataaagat
      361 tacctattct atattctttc atcaaatgta gtttattctc aatttctatc tctaattagt
      421 ggagctgttg tgaaaaactt gaatagtgat aaagttgctt ctattcttat ccctctcccc
      481 ccactatccg aacaacaacg cataatagaa gcaatcgaat cagctttaga aaaagtagat
      541 gaatatgctg aaagttataa tagactagaa cagctagata aagaatttcc agataaacta
      601 aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag ttgaacaaga cccaaatgat
      661 gaatcagtcg aagttttact tgaaaaaata cgagcagaaa aacaaaaact ctttgaagaa
      721 ggcaagatta aaaagaaaga tttggacatt tctattgttt cccaag
//
LOCUS       DAVLAQ010000148          714 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000148 DAVLAQ010000000
VERSION     DAVLAQ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.148"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>714
                     /locus_tag="VXB71_002104"
     CDS             <1..>714
                     /locus_tag="VXB71_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="catalyzes the formation of UDP-glucuronate from
                     UDP-glucose; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0452126.1"
                     /translation="PTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPFGFSN
                     KLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTA
                     NIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPRI
                     GNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKP
                     KIVGIYKLGMKYNSDNYKES"
BASE COUNT          264 a           87 c          130 g          233 t
ORIGIN      
        1 ccgacagatt atgatgagaa aattggtagt tttaatacat atgaaatcga acaaacggta
       61 tcgaagattc tgagggtaaa acctaatgga aagattattt taaagtcaac agttccgttc
      121 ggcttttcaa acaaattaaa aaggctgttt gatacaaaaa atatcatttt tgtccctgaa
      181 tttttgagag aaggttgttc tatatatgat aatttatatc caagtcgcat agttgttgga
      241 gatgagacag ttgaaggaag aaaaattgca gagttgttcc tttcgattag tactcatagt
      301 actgccaata ttaaaaatgt tatgttagtt tctcctactg aagcagaagc aattaagctt
      361 ttttctaaca cattcttagc tctccgtgtt gcttttttta atgaactaga ttcttttgct
      421 gagaggagaa gtttaaatgc tgaagttgta ataaaaggtg tttgtttaga tccaagaatt
      481 ggaaattttt ataataatct ttcttttgga tttggaggat attgtcttcc caaagatact
      541 aaacaattaa aaaaagaatt tatagaaata aatgccccag tgatagaagc gattgatatt
      601 tcaaacacaa atagaaaaca gttcatagtt aaacaaatat tggaacgaaa gccaaagata
      661 gtaggaatat ataaattggg gatgaaatat aattcagata attacaaaga gtca
//
LOCUS       DAVLAQ010000149          652 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000149 DAVLAQ010000000
VERSION     DAVLAQ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.149"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>652
                     /locus_tag="VXB71_002105"
     CDS             <1..>652
                     /locus_tag="VXB71_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0452127.1"
                     /translation="LSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGG
                     LVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNA
                     TQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRL
                     SNVLSDVNVTNGNAIAGYNFNSIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGE"
BASE COUNT          234 a           88 c          142 g          188 t
ORIGIN      
        1 actttcacta aaagatgtta atatttccgc aaaggacgat actgcaacac ttgcgaaaga
       61 agcaaataac aatactcata ttgataacgt tcatgctgat ggagcgatag ctggggaacg
      121 tagcatagga ggattagtat cacaagttaa taattctact atttctaaca gtagctatac
      181 aggtagaata actaatacat ataaaacagt tgctagttat caaatcggag gtttagtagg
      241 caaactttct ggtccgaggg gattaataga taagtcgttc gcatcaatcg atttatcttc
      301 aaatgcaaca caaggagacc agtctattgg tggaatagtt ggtgcagtag aaaatagtgc
      361 gcttattagt aatagttatg ctgaaggaaa tctaaataat gttcaacgtt ttgcaaacgt
      421 tggtggagta gttggtaatc tttgggatcc ggttggagga ttagaaaaat ccggtcgact
      481 ttctaatgta ctaagcgatg ttaatgtaac gaatggtaat gctattgcag gttataattt
      541 taatagtata aaagcaaatg gcacatacag taataaaaat aataaggttg tgaacgtagt
      601 acaagaagat gatgaaatct taactaagga ttctactgtt caaagaggag aa
//
LOCUS       DAVLAQ010000150          629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000150 DAVLAQ010000000
VERSION     DAVLAQ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.150"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>629
                     /gene="phtB"
                     /locus_tag="VXB71_002106"
     CDS             <1..>629
                     /gene="phtB"
                     /locus_tag="VXB71_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV0452128.1"
                     /translation="LKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPH
                     YDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          200 a          129 c          139 g          161 t
ORIGIN      
        1 actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg ccttcttagc
       61 tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct acactgatga
      121 tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt atatctttga
      181 tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata tgacccatag
      241 ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc aggcttatgc
      301 taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa atactgaggc
      361 aaaaggagca gaagctatct acaaccgcgt gaaagcagct aagaaggtgc cacttgatcg
      421 tatgccttac aatcttcaat atactgtaga agtcaaaaac ggtagtttaa tcatacctca
      481 ttatgaccat taccataaca tcaaatttga gtggtttgac gaaggccttt atgaggcacc
      541 taaggggtat actcttgagg atcttttggc gactgtcaag tactatgtcg aacatccaaa
      601 cgaacgtccg cattcagata atggttttg
//
LOCUS       DAVLAQ010000151          607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000151 DAVLAQ010000000
VERSION     DAVLAQ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.151"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>607)
                     /locus_tag="VXB71_002107"
     CDS             complement(<1..>607)
                     /locus_tag="VXB71_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0452129.1"
                     /translation="KNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDF
                     HFKHDFSRLPEIMSWDEYAFTKGKMSFIAQDFEKLDIITVLEGRTQAIIRNHFLRYDR
                     VVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDR
                     KSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEIF"
BASE COUNT          197 a          107 c          122 g          181 t
ORIGIN      
        1 aaaaatctct ttattggtta aatgcatacg aaaagtaggg cgataaaaat gtttatcgct
       61 gagtttacga ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      121 agactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      181 atgttgtaca atgtgaaagc gatccaacac gattttagca cacgggaaaa gttgtctagc
      241 taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac atcggacaac
      301 tctatcgtag cgaagaaagt gatttcgaat gatagcttgt gttctaccct caagaacagt
      361 gatgatatcg agcttttcaa aatcttgcgc aatgaagctc atctttccct ttgtaaaagc
      421 atactcatcc caagacataa tctcaggaag acgcgaaaaa tcatgtttaa agtgaaaatc
      481 attgagctta cgaataacag ttgaagttga gatggaaagc tgatgggcaa tatcagtcat
      541 agaaatcttt tcaattaact tttgagcaat cttttggttg atgatacgag ggatttggtg
      601 attcttc
//
LOCUS       DAVLAQ010000152          599 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000152 DAVLAQ010000000
VERSION     DAVLAQ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.152"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(261..431)
                     /locus_tag="VXB71_002108"
     CDS             complement(261..431)
                     /locus_tag="VXB71_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452130.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            complement(444..>599)
                     /locus_tag="VXB71_002109"
     CDS             complement(444..>599)
                     /locus_tag="VXB71_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0452131.1"
                     /translation="CTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGGEYY
                     SLYTKRK"
BASE COUNT          203 a          115 c           75 g          206 t
ORIGIN      
        1 ctaggaagcg agccgcaggc tgtacttgag tacggtaaag caaagctgac gtggtttgaa
       61 gagattttca aagagtatta aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta
      121 atcatgtttt taagctacta ctgtagttgc tctattattt aagtgttatg aataacttca
      181 atatctttaa agctttttgt tagatttata atttcaacta tagccatctc tactccttag
      241 tttacagcaa aaaattatgc ttaattctta ttgtttttgt aaaaaatcag cgaacccaat
      301 actattccat tcaacaaacc taaagaaata gcatattcaa ctggaaaatc taaaaaaatt
      361 gcaaatacta ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt
      421 actttcttca ttttctttac acctcatttc ctttttgtat ataagctgta gtactctcca
      481 ccaagatcca ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca
      541 aaaataatat ccgcatcctt aatcgttgac aatctatgag ctataattat ttgagtaca
//
LOCUS       DAVLAQ010000153          588 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000153 DAVLAQ010000000
VERSION     DAVLAQ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.153"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>588
                     /locus_tag="VXB71_002110"
     CDS             <1..>588
                     /locus_tag="VXB71_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0452132.1"
                     /translation="LKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDD
                     ECLSLKDISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLK
                     NSSLVMQDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQ
                     KQRLAIASVMCKNSPFIFFDEPSSGMDYSNMIKIS"
BASE COUNT          236 a           66 c          111 g          175 t
ORIGIN      
        1 tttaaagcta gataaaaatg aattaaatgc tttaagttta agagataaag aattaagtaa
       61 attaaaagtt ccttatttaa aagaaggtgg agagtatcag ataaaaaatc ttagctacaa
      121 atttactgat gatgagtgtt taagcttaaa agatatttca ttcaagcttg ggaaaattta
      181 tggcataata ggatccaacg gacgaggaaa atcaacgctt ttaagatgtt taataggtct
      241 tgagaaaaaa tcaaaagaag aaatttattt taagggagag aagctatcta aaaaagaaag
      301 actcaaaaac tcttcacttg ttatgcaaga tgtaaatcat caattattca cagatgaagt
      361 attcaacgag cttagattag gagtaaagaa ttttgatgaa gaaaaggcga aaatcatttt
      421 aaaagattta ggcctggacg aatttattga aaggcatccg atgagtttat caggagggca
      481 aaagcaaagg cttgcaatag catctgttat gtgcaagaat tctccattta tcttttttga
      541 cgaaccttca agtggtatgg attattccaa tatgataaaa atatctga
//
LOCUS       DAVLAQ010000154          581 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.154, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000154 DAVLAQ010000000
VERSION     DAVLAQ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.154"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(21..500)
                     /locus_tag="VXB71_002111"
     CDS             complement(21..500)
                     /locus_tag="VXB71_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0452133.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          149 a          136 c           76 g          220 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc acccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgat
      421 aattcccata aatgaaggta atattcattt ctacacttat acacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc c
//
LOCUS       DAVLAQ010000155          560 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.155, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000155 DAVLAQ010000000
VERSION     DAVLAQ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.155"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(176..472)
                     /locus_tag="VXB71_002112"
     CDS             complement(176..472)
                     /locus_tag="VXB71_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV0452134.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
BASE COUNT          203 a          104 c           71 g          182 t
ORIGIN      
        1 aagtagcgta atctactacc aaaaaaagta aaaataattt cccttgaaaa ggaagatagc
       61 ttttaaaata gattgacaaa cttatgataa caaaaaacaa aagggttatc ccaataaaat
      121 taagataacc taaaatactt tcacattctt ttttagaaag tattttcatc tagttctacc
      181 atagagctgc tttagcagca cctttctttt tcaatatata aagaactgtt gctgcaatac
      241 ccgaaccaat agaacctact cctgtgattg cacctacaat tgaaattact gctgtaactg
      301 tactataagc actaatcaaa ttgactacag tagcagcagc ttttgtcgaa attcctaatg
      361 tcccagccaa cataggaaaa gaaacaacac ctaagcttaa ccaactaatg actgctaaca
      421 ttgctgaaac aataagaaat ttattatgaa attccattct tttagatttc attttagtgt
      481 actccttttg tatattatgt atgttttatt gagagttaat tcgcacatgt tgtattccta
      541 actctcttca aatgttcgtc
//
LOCUS       DAVLAQ010000156          486 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.156, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000156 DAVLAQ010000000
VERSION     DAVLAQ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.156"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>486
                     /locus_tag="VXB71_002113"
     CDS             <1..>486
                     /locus_tag="VXB71_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0452135.1"
                     /translation="TQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTSSID
                     RKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIAST
                     AFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQ
                     RI"
BASE COUNT          177 a           75 c           71 g          163 t
ORIGIN      
        1 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggataaaa
       61 tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta tatagatacg
      121 tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata tctttcacct
      181 gaacaagcgc cttcccgtgc tagaaaatta gtttcgcaga atagtgtctt attttcaaca
      241 gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta tttgatagct
      301 agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa atattattta
      361 ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag ttatcctgca
      421 atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc cgaacaacaa
      481 cgaata
//
LOCUS       DAVLAQ010000157          427 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.157, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000157 DAVLAQ010000000
VERSION     DAVLAQ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.157"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>427
                     /locus_tag="VXB71_002114"
     CDS             <1..>427
                     /locus_tag="VXB71_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0452136.1"
                     /translation="IASVQASGRNLFLNSLFKQDISKTGIWTTSTYTAAIDSESKYLG
                     HKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLR
                     SRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTN"
BASE COUNT          149 a           75 c           94 g          109 t
ORIGIN      
        1 ggattgcgag tgtgcaggca tccggtcgaa atctattctt gaactcacta ttcaagcagg
       61 atatttcaaa aacaggaatt tggacaacga gtacatatac ggctgctatc gatagcgaaa
      121 gtaagtatct tggacataag gctcttaaaa ttataggtct gaatccatct ggccgtgatg
      181 gagggaatcc caaggttact tacccagctc tgggtcaatt cgggaaagta attcccggaa
      241 gtacgactaa tcaagatgta accattagtt tttatgctaa ggcaaataaa aatggaataa
      301 tgctaagatc tcgattaggg aatatcggat ataaaactgg aaatgtgaca ttgtcgacag
      361 aaattaaacg atatgttgtc catattccaa aaggttggac aaacgaatcc aagcagacca
      421 caaatga
//
LOCUS       DAVLAQ010000158          420 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036549
            SAMN33606689-rid17946593.denovo.158, whole genome shotgun sequence.
ACCESSION   DAVLAQ010000158 DAVLAQ010000000
VERSION     DAVLAQ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606689
            Sequence Read Archive: SRR23726140
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722017.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722017.1
            Genome Coverage       :: 192x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:35:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,115
            CDSs (total)                      :: 2,070
            Genes (coding)                    :: 1,952
            CDSs (with protein)               :: 1,952
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 59 of 118
            Pseudo Genes (incomplete)         :: 50 of 118
            Pseudo Genes (internal stop)      :: 45 of 118
            Pseudo Genes (multiple problems)  :: 29 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606689-rid17946593.denovo.158"
                     /strain="AUSMDU00036549"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>420)
                     /locus_tag="VXB71_002115"
     CDS             complement(<1..>420)
                     /locus_tag="VXB71_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0452137.1"
                     /translation="IDKGIYRVEGENGSGKSTLLQLLAGLETFDSGLKNCVSKDVLYL
                     DTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINTFFDNKIGDNYMTASTGTKFKL
                     GLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISMK"
BASE COUNT          144 a           79 c           55 g          142 t
ORIGIN      
        1 tttcatggaa attaagcgtt tagcaatcat atcaatactt cttgcatcca ctgttgataa
       61 agtctcatca ataaaaatat aatcccaatt tttagcaaaa attaaggata agcctaattt
      121 gaattttgtt ccagtagatg ctgtcatata gttatctccg attttattat caaaaaaagt
      181 attaatttgt tctttatcct caaatgatag atggatttga aaagaatcac acaacaactg
      241 caaattttct tctatagtaa atggaacaac cccaagctga ttggtatcaa ggtatagtac
      301 atctttggag acacaattct ttaaaccact atcaaaagtc tctagcccag ctaaaagttg
      361 tagaagggtg ctctttcctg aaccattctc tccttcaact ctgtaaattc ccttatcaat
//
